SYQ - ECOLI - GREMLIN Contacts

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SYQ - Glutamine--tRNA ligase

UniProt:	P00962	Sequences: MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10390
Length:	554 (533)
Sequences:	2516 (1263)
Seq/√Len:	54.7

ECOLI - SYQ SYE
HALSA - SYE
SULSO - SYE

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
143_N	148_D	5.475	1.00
112_I	159_E	4.437	1.00
167_E	170_K	4.135	1.00
156_A	160_K	4.032	1.00
150_S	154_N	4.026	1.00
124_E	171_A	3.920	1.00
160_K	165_G	3.911	1.00
76_I	80_E	3.835	1.00
395_E	425_K	3.799	1.00
467_P	503_F	3.748	1.00
105_D	205_K	3.624	1.00
365_T	379_Q	3.258	1.00
424_E	433_T	3.256	1.00
355_E	435_F	3.228	1.00
125_L	133_Y	3.152	1.00
468_V	504_A	3.100	1.00
119_L	247_N	3.067	1.00
348_D	390_R	3.064	1.00
426_D	430_N	2.992	1.00
353_V	435_F	2.946	1.00
105_D	109_A	2.926	1.00
366_M	414_N	2.865	1.00
512_V	515_K	2.785	1.00
168_E	196_F	2.714	1.00
352_L	418_I	2.660	1.00
275_N	279_T	2.649	1.00
113_E	117_K	2.641	1.00
487_D	490_S	2.621	1.00
198_E	204_N	2.619	1.00
87_E	92_H	2.580	1.00
107_L	219_S	2.535	1.00
17_D	58_Y	2.522	1.00
39_Y	77_E	2.514	1.00
126_T	129_Q	2.501	1.00
363_M	379_Q	2.485	1.00
303_T	335_D	2.475	1.00
359_G	384_G	2.453	1.00
160_K	166_F	2.435	1.00
405_V	408_K	2.405	1.00
159_E	163_A	2.329	1.00
167_E	196_F	2.260	1.00
461_S	464_H	2.245	1.00
470_I	502_G	2.236	1.00
350_V	434_I	2.198	1.00
115_I	158_F	2.198	1.00
345_A	504_A	2.156	1.00
47_S	231_T	2.130	1.00
409_E	451_R	2.129	1.00
383_S	461_S	2.115	1.00
112_I	116_N	2.099	1.00
105_D	162_R	2.098	1.00
246_D	253_H	2.090	1.00
467_P	501_Q	2.059	1.00
422_R	435_F	2.056	1.00
276_L	280_D	2.028	1.00
18_E	21_A	2.013	1.00
191_L	244_V	2.002	1.00
156_A	165_G	2.001	1.00
143_N	179_M	1.989	1.00
348_D	498_V	1.961	1.00
495_E	498_V	1.955	1.00
305_A	339_N	1.919	1.00
49_C	91_F	1.903	1.00
129_Q	132_E	1.895	1.00
309_E	313_R	1.889	1.00
372_K	375_M	1.886	0.99
335_D	339_N	1.873	0.99
63_N	96_N	1.870	0.99
162_R	208_I	1.869	0.99
13_R	57_D	1.865	0.99
365_T	377_S	1.861	0.99
100_S	215_T	1.856	0.99
421_E	437_T	1.853	0.99
157_L	166_F	1.841	0.99
111_A	173_L	1.837	0.99
83_K	97_V	1.831	0.99
133_Y	142_K	1.819	0.99
113_E	249_T	1.817	0.99
465_A	503_F	1.799	0.99
439_D	451_R	1.789	0.99
106_Q	110_Y	1.785	0.99
413_R	520_E	1.785	0.99
351_K	385_E	1.781	0.99
337_N	371_N	1.745	0.99
541_R	544_G	1.724	0.99
136_T	139_Q	1.720	0.99
469_E	499_I	1.713	0.99
519_F	539_F	1.706	0.99
64_L	83_K	1.701	0.99
29_H	61_Q	1.696	0.99
353_V	433_T	1.692	0.99
29_H	225_I	1.691	0.99
389_D	522_E	1.677	0.99
355_E	422_R	1.677	0.99
18_E	22_S	1.665	0.99
213_D	237_N	1.663	0.99
27_T	61_Q	1.662	0.99
102_D	201_Q	1.658	0.99
381_P	506_P	1.657	0.99
52_F	62_C	1.654	0.99
355_E	433_T	1.645	0.99
345_A	468_V	1.644	0.99
156_A	166_F	1.644	0.99
511_A	517_F	1.626	0.98
185_V	237_N	1.625	0.98
360_E	463_A	1.618	0.98
117_K	249_T	1.617	0.98
422_R	434_I	1.615	0.98
424_E	435_F	1.607	0.98
124_E	149_R	1.593	0.98
79_V	200_H	1.590	0.98
284_E	497_L	1.586	0.98
478_S	491_V	1.576	0.98
305_A	335_D	1.570	0.98
465_A	506_P	1.569	0.98
108_H	159_E	1.559	0.98
29_H	63_N	1.556	0.98
106_Q	222_L	1.536	0.98
477_F	482_P	1.535	0.98
47_S	229_L	1.530	0.98
527_L	532_S	1.523	0.98
47_S	51_N	1.520	0.98
80_E	83_K	1.518	0.98
106_Q	109_A	1.514	0.98
409_E	439_D	1.510	0.98
116_N	155_L	1.509	0.98
117_K	247_N	1.508	0.97
47_S	50_L	1.485	0.97
353_V	385_E	1.481	0.97
110_Y	218_I	1.472	0.97
419_K	437_T	1.468	0.97
83_K	87_E	1.466	0.97
125_L	142_K	1.461	0.97
269_M	275_N	1.455	0.97
221_A	251_P	1.450	0.97
130_I	172_C	1.450	0.97
151_V	154_N	1.445	0.97
302_Y	328_L	1.434	0.97
284_E	531_H	1.432	0.97
107_L	215_T	1.407	0.96
472_L	541_R	1.394	0.96
282_H	489_L	1.394	0.96
533_T	536_K	1.393	0.96
479_V	491_V	1.383	0.96
276_L	488_F	1.380	0.96
348_D	391_A	1.378	0.96
367_P	413_R	1.372	0.96
110_Y	222_L	1.370	0.96
381_P	464_H	1.369	0.96
116_N	152_E	1.359	0.95
369_H	375_M	1.352	0.95
266_Y	480_P	1.351	0.95
80_E	84_N	1.350	0.95
185_V	236_D	1.341	0.95
123_D	130_I	1.327	0.95
109_A	116_N	1.320	0.95
260_S	317_T	1.307	0.94
414_N	520_E	1.306	0.94
303_T	306_S	1.303	0.94
196_F	207_C	1.301	0.94
409_E	419_K	1.293	0.94
122_V	173_L	1.287	0.94
352_L	386_I	1.280	0.94
116_N	159_E	1.279	0.94
25_H	28_V	1.278	0.94
514_G	529_S	1.278	0.94
78_Y	275_N	1.277	0.94
424_E	434_I	1.276	0.93
218_I	248_I	1.267	0.93
357_Y	383_S	1.262	0.93
244_V	248_I	1.255	0.93
260_S	321_N	1.254	0.93
274_L	292_P	1.252	0.93
469_E	536_K	1.251	0.93
46_K	262_L	1.247	0.93
343_A	507_S	1.246	0.93
218_I	222_L	1.246	0.93
332_I	542_T	1.244	0.93
417_V	449_D	1.238	0.92
354_I	438_Y	1.234	0.92
343_A	368_N	1.228	0.92
61_Q	96_N	1.225	0.92
361_G	463_A	1.224	0.92
472_L	525_F	1.219	0.92
100_S	219_S	1.211	0.92
217_C	244_V	1.204	0.91
404_L	418_I	1.202	0.91
363_M	381_P	1.199	0.91
303_T	332_I	1.193	0.91
276_L	489_L	1.184	0.91
516_A	542_T	1.179	0.90
24_K	27_T	1.175	0.90
95_G	98_R	1.174	0.90
390_R	430_N	1.173	0.90
313_R	331_C	1.170	0.90
394_R	398_N	1.167	0.90
109_A	112_I	1.166	0.90
124_E	150_S	1.163	0.90
273_K	483_G	1.157	0.90
17_D	57_D	1.141	0.89
479_V	485_A	1.135	0.89
466_L	504_A	1.133	0.89
471_R	531_H	1.124	0.88
108_H	208_I	1.122	0.88
124_E	170_K	1.120	0.88
10_N	54_I	1.119	0.88
347_I	470_I	1.117	0.88
420_A	434_I	1.114	0.88
185_V	239_R	1.113	0.88
483_G	491_V	1.112	0.88
350_V	390_R	1.112	0.88
23_G	26_T	1.105	0.87
355_E	421_E	1.100	0.87
52_F	91_F	1.098	0.87
10_N	57_D	1.095	0.87
309_E	331_C	1.091	0.87
394_R	397_A	1.090	0.87
110_Y	217_C	1.088	0.87
149_R	153_E	1.083	0.86
172_C	190_V	1.081	0.86
338_E	371_N	1.076	0.86
351_K	433_T	1.075	0.86
402_K	405_V	1.072	0.86
367_P	520_E	1.070	0.86
141_G	184_I	1.067	0.85
84_N	87_E	1.067	0.85
352_L	434_I	1.065	0.85
221_A	250_I	1.063	0.85
265_E	324_E	1.063	0.85
297_L	306_S	1.058	0.85
417_V	448_A	1.057	0.85
418_I	436_C	1.057	0.85
361_G	464_H	1.051	0.85
125_L	144_S	1.049	0.84
344_M	460_V	1.045	0.84
229_L	257_Y	1.044	0.84
420_A	436_C	1.042	0.84
113_E	116_N	1.042	0.84
92_H	96_N	1.041	0.84
406_L	420_A	1.041	0.84
513_A	527_L	1.036	0.84
346_V	460_V	1.034	0.84
213_D	240_L	1.026	0.83
426_D	432_T	1.026	0.83
20_L	25_H	1.025	0.83
118_G	154_N	1.025	0.83
229_L	316_V	1.024	0.83
297_L	332_I	1.020	0.83
17_D	21_A	1.017	0.83
9_T	13_R	1.015	0.82
323_I	327_S	1.009	0.82
383_S	463_A	1.005	0.82
299_R	528_D	1.005	0.82
22_S	25_H	1.005	0.82
251_P	254_P	1.000	0.81
261_R	270_S	0.993	0.81
160_K	171_A	0.992	0.81
186_M	239_R	0.992	0.81
380_V	460_V	0.989	0.81
237_N	240_L	0.983	0.80
131_R	137_L	0.980	0.80
311_C	314_I	0.979	0.80
218_I	250_I	0.977	0.80
280_D	488_F	0.977	0.80
54_I	229_L	0.975	0.80
50_L	231_T	0.968	0.79
62_C	91_F	0.963	0.79
92_H	98_R	0.961	0.79
383_S	465_A	0.959	0.79
215_T	219_S	0.955	0.78
410_V	457_I	0.952	0.78
511_A	527_L	0.949	0.78
421_E	436_C	0.948	0.78
324_E	480_P	0.943	0.78
245_L	248_I	0.942	0.77
276_L	282_H	0.938	0.77
63_N	98_R	0.937	0.77
86_V	231_T	0.935	0.77
84_N	295_S	0.935	0.77
479_V	484_A	0.935	0.77
416_Y	438_Y	0.926	0.76
423_V	434_I	0.926	0.76
63_N	95_G	0.923	0.76
486_D	490_S	0.921	0.76
166_F	170_K	0.917	0.76
471_R	538_V	0.916	0.75
529_S	532_S	0.913	0.75
422_R	433_T	0.911	0.75
137_L	236_D	0.908	0.75
72_V	195_K	0.908	0.75
128_E	132_E	0.908	0.75
506_P	509_K	0.908	0.75
313_R	327_S	0.904	0.74
302_Y	332_I	0.902	0.74
47_S	311_C	0.902	0.74
218_I	244_V	0.899	0.74
245_L	253_H	0.898	0.74
341_P	515_K	0.898	0.74
331_C	334_E	0.898	0.74
408_K	457_I	0.896	0.74
29_H	96_N	0.894	0.74
526_C	529_S	0.886	0.73
72_V	75_D	0.886	0.73
112_I	163_A	0.885	0.73
481_N	484_A	0.883	0.73
124_E	154_N	0.882	0.73
369_H	376_G	0.879	0.72
127_P	131_R	0.878	0.72
217_C	237_N	0.878	0.72
383_S	464_H	0.876	0.72
302_Y	329_E	0.874	0.72
504_A	537_P	0.874	0.72
94_S	98_R	0.873	0.72
395_E	423_V	0.872	0.72
357_Y	362_E	0.872	0.72
266_Y	475_R	0.871	0.72
107_L	218_I	0.865	0.71
110_Y	113_E	0.864	0.71
302_Y	306_S	0.863	0.71
160_K	163_A	0.862	0.71
527_L	537_P	0.861	0.71
122_V	154_N	0.858	0.71
354_I	436_C	0.858	0.71
350_V	356_N	0.857	0.70
63_N	94_S	0.856	0.70
178_D	181_S	0.853	0.70
45_A	307_I	0.844	0.69
514_G	527_L	0.843	0.69
385_E	462_A	0.843	0.69
353_V	424_E	0.842	0.69
504_A	508_L	0.841	0.69
397_A	406_L	0.840	0.69
49_C	53_G	0.838	0.69
396_E	399_K	0.837	0.69
327_S	330_S	0.835	0.68
214_F	244_V	0.835	0.68
235_Q	257_Y	0.835	0.68
398_N	408_K	0.832	0.68
330_S	334_E	0.831	0.68
47_S	86_V	0.830	0.68
123_D	133_Y	0.830	0.68
380_V	414_N	0.829	0.68
13_R	54_I	0.828	0.68
103_Y	219_S	0.827	0.68
130_I	190_V	0.823	0.67
181_S	186_M	0.820	0.67
352_L	436_C	0.819	0.67
366_M	380_V	0.818	0.67
534_A	537_P	0.817	0.67
170_K	196_F	0.817	0.67
385_E	463_A	0.815	0.67
49_C	308_R	0.815	0.67
83_K	93_W	0.813	0.66
389_D	458_H	0.811	0.66
149_R	157_L	0.807	0.66
361_G	461_S	0.807	0.66
338_E	372_K	0.804	0.65
441_D	448_A	0.804	0.65
10_N	13_R	0.804	0.65
419_K	439_D	0.801	0.65
448_A	451_R	0.798	0.65
409_E	453_V	0.797	0.65
394_R	401_Y	0.791	0.64
474_D	549_W	0.790	0.64
116_N	151_V	0.789	0.64
260_S	319_Q	0.789	0.64
469_E	538_V	0.787	0.64
355_E	424_E	0.786	0.64
404_L	457_I	0.786	0.64
424_E	432_T	0.786	0.64
341_P	368_N	0.783	0.63
242_D	246_D	0.780	0.63
398_N	406_L	0.779	0.63
181_S	239_R	0.778	0.63
132_E	140_P	0.778	0.63
129_Q	133_Y	0.777	0.63
417_V	456_V	0.775	0.63
513_A	526_C	0.774	0.63
119_L	123_D	0.774	0.63
274_L	291_M	0.773	0.62
397_A	405_V	0.773	0.62
191_L	214_F	0.773	0.62
391_A	522_E	0.772	0.62
17_D	20_L	0.771	0.62
464_H	506_P	0.770	0.62
394_R	405_V	0.769	0.62
76_I	79_V	0.769	0.62
303_T	516_A	0.769	0.62
150_S	153_E	0.767	0.62
369_H	372_K	0.766	0.62
116_N	205_K	0.764	0.62
79_V	99_Y	0.764	0.62
394_R	399_K	0.763	0.61
402_K	454_K	0.763	0.61
61_Q	94_S	0.762	0.61
421_E	434_I	0.759	0.61
122_V	171_A	0.758	0.61
103_Y	106_Q	0.756	0.61
397_A	400_Q	0.756	0.61
85_D	295_S	0.756	0.61
516_A	526_C	0.755	0.61
112_I	155_L	0.755	0.61
501_Q	536_K	0.755	0.61
9_T	14_Q	0.754	0.61
93_W	97_V	0.754	0.61
482_P	491_V	0.751	0.60
313_R	334_E	0.750	0.60
116_N	119_L	0.749	0.60
306_S	332_I	0.748	0.60
486_D	491_V	0.748	0.60
100_S	107_L	0.748	0.60
51_N	231_T	0.747	0.60
10_N	17_D	0.746	0.60
362_E	438_Y	0.746	0.60
242_D	255_R	0.743	0.59
150_S	171_A	0.742	0.59
13_R	520_E	0.741	0.59
50_L	294_I	0.740	0.59
132_E	142_K	0.740	0.59
471_R	499_I	0.737	0.59
357_Y	361_G	0.734	0.58
221_A	254_P	0.734	0.58
479_V	483_G	0.732	0.58
343_A	508_L	0.732	0.58
338_E	369_H	0.732	0.58
221_A	249_T	0.731	0.58
184_I	190_V	0.729	0.58
217_C	240_L	0.729	0.58
15_I	257_Y	0.728	0.58
16_I	58_Y	0.727	0.58
264_L	314_I	0.727	0.58
156_A	159_E	0.726	0.58
190_V	211_M	0.725	0.57
427_A	432_T	0.724	0.57
403_R	410_V	0.724	0.57
48_I	91_F	0.723	0.57
388_I	393_F	0.722	0.57
86_V	91_F	0.721	0.57
341_P	375_M	0.721	0.57
355_E	437_T	0.720	0.57
123_D	144_S	0.719	0.57
112_I	151_V	0.719	0.57
367_P	414_N	0.718	0.57
177_I	189_P	0.718	0.57
42_I	297_L	0.718	0.57
357_Y	384_G	0.716	0.57
508_L	511_A	0.714	0.56
92_H	97_V	0.714	0.56
29_H	224_G	0.713	0.56
464_H	468_V	0.713	0.56
358_Q	384_G	0.712	0.56
118_G	148_D	0.712	0.56
451_R	456_V	0.712	0.56
304_A	516_A	0.712	0.56
354_I	382_F	0.708	0.56
351_K	462_A	0.708	0.56
218_I	245_L	0.705	0.55
106_Q	218_I	0.704	0.55
395_E	431_I	0.704	0.55
15_I	24_K	0.703	0.55
50_L	314_I	0.703	0.55
266_Y	477_F	0.702	0.55
159_E	162_R	0.701	0.55
124_E	146_Y	0.700	0.55
125_L	146_Y	0.699	0.55
238_R	258_E	0.699	0.55
467_P	502_G	0.697	0.55
146_Y	154_N	0.697	0.55
166_F	171_A	0.696	0.54
137_L	184_I	0.696	0.54
278_V	291_M	0.695	0.54
513_A	529_S	0.693	0.54
397_A	408_K	0.693	0.54
485_A	491_V	0.693	0.54
12_I	229_L	0.693	0.54
418_I	434_I	0.691	0.54
51_N	54_I	0.688	0.54
394_R	420_A	0.687	0.53
486_D	511_A	0.686	0.53
282_H	492_I	0.686	0.53
425_K	431_I	0.686	0.53
107_L	217_C	0.685	0.53
61_Q	95_G	0.685	0.53
405_V	457_I	0.684	0.53
517_F	527_L	0.681	0.53
474_D	498_V	0.677	0.52
381_P	461_S	0.676	0.52
137_L	185_V	0.672	0.52
141_G	182_P	0.671	0.52
196_F	204_N	0.670	0.52
185_V	235_Q	0.669	0.52
108_H	206_W	0.668	0.51
25_H	255_R	0.668	0.51
20_L	255_R	0.667	0.51
266_Y	482_P	0.667	0.51
466_L	509_K	0.666	0.51
348_D	430_N	0.665	0.51
469_E	500_K	0.665	0.51
507_S	510_D	0.664	0.51
20_L	24_K	0.663	0.51
356_N	438_Y	0.662	0.51
401_Y	457_I	0.661	0.51
356_N	437_T	0.660	0.51
317_T	327_S	0.659	0.50
183_F	239_R	0.659	0.50
305_A	309_E	0.658	0.50
267_T	325_M	0.658	0.50
468_V	537_P	0.656	0.50
9_T	17_D	0.656	0.50
217_C	245_L	0.655	0.50
19_D	24_K	0.654	0.50
245_L	254_P	0.652	0.50
514_G	526_C	0.650	0.50
242_D	253_H	0.650	0.50
338_E	542_T	0.648	0.49
22_S	26_T	0.647	0.49
191_L	217_C	0.644	0.49
372_K	380_V	0.644	0.49
358_Q	362_E	0.642	0.49
107_L	213_D	0.642	0.49
143_N	180_A	0.642	0.49
483_G	489_L	0.641	0.49
212_Y	271_K	0.641	0.49
358_Q	438_Y	0.640	0.48
106_Q	113_E	0.638	0.48
33_P	231_T	0.638	0.48
72_V	197_A	0.637	0.48
413_R	457_I	0.636	0.48
92_H	95_G	0.635	0.48
110_Y	248_I	0.635	0.48
125_L	130_I	0.634	0.48
66_F	231_T	0.633	0.48
221_A	248_I	0.633	0.48
368_N	380_V	0.632	0.48
14_Q	18_E	0.631	0.47
61_Q	98_R	0.631	0.47
55_A	60_G	0.631	0.47
246_D	249_T	0.629	0.47
99_Y	201_Q	0.627	0.47
423_V	431_I	0.626	0.47
500_K	503_F	0.625	0.47
108_H	162_R	0.625	0.47
114_L	191_L	0.624	0.47
66_F	97_V	0.623	0.47
261_R	273_K	0.623	0.47
29_H	226_T	0.622	0.47
229_L	311_C	0.622	0.47
385_E	435_F	0.621	0.46
361_G	381_P	0.619	0.46
55_A	62_C	0.619	0.46
144_S	179_M	0.619	0.46
152_E	156_A	0.619	0.46
499_I	536_K	0.618	0.46
62_C	86_V	0.618	0.46
81_S	295_S	0.618	0.46
533_T	537_P	0.618	0.46
503_F	512_V	0.618	0.46
94_S	97_V	0.617	0.46
221_A	247_N	0.617	0.46
485_A	490_S	0.617	0.46
175_A	191_L	0.617	0.46
303_T	328_L	0.615	0.46
123_D	184_I	0.615	0.46
354_I	386_I	0.614	0.46
110_Y	250_I	0.614	0.46
29_H	95_G	0.614	0.46
478_S	483_G	0.614	0.46
110_Y	244_V	0.613	0.46
479_V	486_D	0.612	0.45
470_I	501_Q	0.612	0.45
317_T	321_N	0.611	0.45
357_Y	438_Y	0.610	0.45
527_L	539_F	0.610	0.45
52_F	308_R	0.609	0.45
368_N	507_S	0.608	0.45
466_L	537_P	0.604	0.45
396_E	408_K	0.604	0.45
110_Y	249_T	0.604	0.45
112_I	158_F	0.604	0.45
118_G	151_V	0.603	0.44
185_V	217_C	0.603	0.44
500_K	536_K	0.603	0.44
426_D	429_G	0.603	0.44
484_A	491_V	0.602	0.44
402_K	406_L	0.602	0.44
30_T	33_P	0.600	0.44
268_V	320_D	0.600	0.44
469_E	531_H	0.600	0.44
467_P	504_A	0.599	0.44
248_I	251_P	0.599	0.44
135_G	141_G	0.599	0.44
234_F	241_Y	0.597	0.44
408_K	419_K	0.597	0.44
481_N	486_D	0.597	0.44
15_I	255_R	0.596	0.44
109_A	113_E	0.595	0.44
381_P	465_A	0.595	0.44
371_N	457_I	0.595	0.44
422_R	432_T	0.594	0.44
29_H	94_S	0.594	0.44
514_G	542_T	0.593	0.43
357_Y	416_Y	0.593	0.43
326_A	330_S	0.590	0.43
108_H	112_I	0.589	0.43
526_C	542_T	0.589	0.43
87_E	116_N	0.587	0.43
477_F	481_N	0.587	0.43
270_S	273_K	0.587	0.43
504_A	519_F	0.586	0.43
297_L	307_I	0.585	0.43
149_R	154_N	0.585	0.43
348_D	501_Q	0.584	0.42
149_R	171_A	0.583	0.42
235_Q	239_R	0.582	0.42
345_A	519_F	0.580	0.42
478_S	494_P	0.580	0.42
213_D	234_F	0.578	0.42
276_L	487_D	0.578	0.42
23_G	224_G	0.577	0.42
24_K	255_R	0.576	0.42
475_R	479_V	0.576	0.42
52_F	56_Q	0.576	0.42
175_A	244_V	0.576	0.42
191_L	218_I	0.575	0.42
20_L	58_Y	0.575	0.42
368_N	377_S	0.575	0.42
309_E	312_K	0.574	0.41
16_I	54_I	0.574	0.41
413_R	458_H	0.573	0.41
348_D	500_K	0.573	0.41
48_I	86_V	0.573	0.41
181_S	184_I	0.572	0.41
396_E	407_G	0.572	0.41
204_N	207_C	0.572	0.41
417_V	451_R	0.571	0.41
39_Y	81_S	0.571	0.41
461_S	465_A	0.571	0.41
16_I	20_L	0.571	0.41
111_A	192_Y	0.570	0.41
355_E	384_G	0.569	0.41
115_I	173_L	0.569	0.41
60_G	226_T	0.568	0.41
122_V	157_L	0.568	0.41
327_S	544_G	0.568	0.41
107_L	110_Y	0.567	0.41
352_L	424_E	0.567	0.41
325_M	329_E	0.567	0.41
20_L	26_T	0.566	0.41
16_I	19_D	0.565	0.41
340_A	516_A	0.564	0.40
168_E	195_K	0.564	0.40
479_V	490_S	0.564	0.40
280_D	489_L	0.564	0.40
354_I	418_I	0.563	0.40
72_V	76_I	0.562	0.40
466_L	536_K	0.562	0.40
474_D	547_D	0.561	0.40
187_R	193_R	0.561	0.40
394_R	402_K	0.560	0.40
124_E	157_L	0.559	0.40
527_L	533_T	0.559	0.40
113_E	248_I	0.559	0.40
217_C	542_T	0.558	0.40
311_C	317_T	0.558	0.40
25_H	257_Y	0.558	0.40
13_R	17_D	0.556	0.40
362_E	382_F	0.556	0.40
51_N	225_I	0.556	0.40
348_D	495_E	0.555	0.39
372_K	376_G	0.555	0.39
302_Y	307_I	0.554	0.39
303_T	339_N	0.554	0.39
21_A	24_K	0.553	0.39
361_G	365_T	0.553	0.39
512_V	517_F	0.552	0.39
154_N	171_A	0.552	0.39
357_Y	382_F	0.552	0.39
297_L	543_V	0.552	0.39
11_F	15_I	0.552	0.39
99_Y	102_D	0.551	0.39
269_M	297_L	0.551	0.39
134_R	185_V	0.551	0.39
215_T	222_L	0.550	0.39
135_G	140_P	0.550	0.39
353_V	434_I	0.549	0.39
273_K	482_P	0.549	0.39
481_N	485_A	0.549	0.39
498_V	503_F	0.549	0.39
351_K	356_N	0.548	0.39
127_P	190_V	0.548	0.39
185_V	319_Q	0.548	0.39
337_N	368_N	0.547	0.39
478_S	490_S	0.547	0.39
261_R	274_L	0.547	0.39
156_A	171_A	0.547	0.39
262_L	269_M	0.547	0.39
160_K	168_E	0.546	0.39
211_M	244_V	0.545	0.38
211_M	217_C	0.545	0.38
434_I	437_T	0.545	0.38
49_C	52_F	0.545	0.38
323_I	326_A	0.543	0.38
274_L	296_G	0.543	0.38
31_R	34_P	0.542	0.38
256_Q	403_R	0.542	0.38
344_M	380_V	0.542	0.38
156_A	163_A	0.541	0.38
237_N	244_V	0.541	0.38
431_I	434_I	0.541	0.38
23_G	27_T	0.540	0.38
79_V	201_Q	0.539	0.38
199_H	203_G	0.539	0.38
368_N	376_G	0.538	0.38
245_L	250_I	0.538	0.38
15_I	20_L	0.536	0.38
537_P	541_R	0.536	0.38
513_A	532_S	0.535	0.37
327_S	331_C	0.535	0.37
341_P	367_P	0.534	0.37
113_E	247_N	0.534	0.37
143_N	147_R	0.534	0.37
244_V	247_N	0.533	0.37
427_A	466_L	0.532	0.37
483_G	490_S	0.532	0.37
470_I	503_F	0.532	0.37
473_Y	497_L	0.532	0.37
471_R	497_L	0.532	0.37
401_Y	408_K	0.531	0.37
219_S	237_N	0.531	0.37
337_N	369_H	0.531	0.37
72_V	80_E	0.531	0.37
48_I	51_N	0.531	0.37
339_N	372_K	0.531	0.37
408_K	449_D	0.531	0.37
129_Q	146_Y	0.530	0.37
131_R	134_R	0.529	0.37
250_I	253_H	0.529	0.37
309_E	330_S	0.529	0.37
141_G	179_M	0.528	0.37
148_D	179_M	0.528	0.37
409_E	448_A	0.527	0.37
507_S	517_F	0.527	0.37
475_R	482_P	0.527	0.37
499_I	531_H	0.527	0.37
510_D	535_E	0.526	0.37
157_L	171_A	0.525	0.36
419_K	449_D	0.525	0.36
402_K	453_V	0.525	0.36
175_A	243_W	0.524	0.36
409_E	417_V	0.524	0.36
347_I	502_G	0.523	0.36
396_E	434_I	0.523	0.36
34_P	43_G	0.522	0.36
38_G	43_G	0.522	0.36
179_M	184_I	0.522	0.36
531_H	534_A	0.522	0.36
275_N	327_S	0.521	0.36
495_E	534_A	0.521	0.36
498_V	501_Q	0.520	0.36
20_L	481_N	0.520	0.36
184_I	237_N	0.519	0.36
17_D	54_I	0.518	0.36
11_F	19_D	0.518	0.36
113_E	119_L	0.518	0.36
99_Y	107_L	0.518	0.36
319_Q	327_S	0.517	0.36
402_K	456_V	0.516	0.36
190_V	195_K	0.516	0.36
309_E	335_D	0.515	0.35
419_K	451_R	0.513	0.35
263_N	270_S	0.511	0.35
378_R	507_S	0.509	0.35
240_L	244_V	0.509	0.35
99_Y	200_H	0.508	0.35
402_K	420_A	0.508	0.35
425_K	432_T	0.508	0.35
270_S	274_L	0.507	0.35
483_G	486_D	0.507	0.35
302_Y	543_V	0.505	0.34
511_A	537_P	0.505	0.34
544_G	547_D	0.505	0.34
528_D	540_N	0.505	0.34
15_I	19_D	0.504	0.34
343_A	511_A	0.504	0.34
183_F	235_Q	0.504	0.34
269_M	449_D	0.504	0.34
110_Y	214_F	0.503	0.34
478_S	485_A	0.503	0.34
168_E	207_C	0.503	0.34
249_T	253_H	0.502	0.34
99_Y	219_S	0.502	0.34
193_R	301_G	0.502	0.34
36_P	43_G	0.502	0.34
124_E	160_K	0.502	0.34
484_A	490_S	0.502	0.34
139_Q	142_K	0.502	0.34
479_V	482_P	0.501	0.34
532_S	536_K	0.501	0.34
483_G	488_F	0.501	0.34
474_D	541_R	0.500	0.34

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2hz7A	1	0.9567	100	0.177	Contact Map
1qtqA	1	0.9549	100	0.182	Contact Map
5bnzA	1	0.9801	100	0.196	Contact Map
4p2bA	2	0.9007	100	0.218	Contact Map
4r3zC	1	0.9278	100	0.23	Contact Map
4h3sA	1	0.9585	100	0.242	Contact Map
3aiiA	1	0.8195	100	0.355	Contact Map
2cfoA	1	0.8267	100	0.6	Contact Map
4griA	1	0.8213	100	0.609	Contact Map
3al0C	1	0.7834	100	0.616	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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