SYM - ECOLI - GREMLIN Contacts

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SYM - Methionine--tRNA ligase

UniProt:	P00959	Sequences: MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSVSFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPSNLFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLASELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLNTELTWDGIQQPLLGHKVNPFKALYNRIDMRQVEALVEASKEEVKAAAAPVTGPLADDPIQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10586
Length:	677 (553)
Sequences:	13197 (6586)
Seq/√Len:	280.1

ECOLI - SYM SYV SYI SYL
BACSU - SYM SYV SYI SYL
HALSA - SYM SYI SYV SYL
SULSO - SYM SYV SYI SYL2 SYL1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
39_Q	44_H	5.900	1.00
332_A	338_R	3.847	1.00
200_E	204_A	3.782	1.00
428_V	444_E	3.666	1.00
117_N	312_G	3.643	1.00
69_T	72_Q	3.558	1.00
113_R	116_E	3.554	1.00
42_R	430_G	3.504	1.00
130_D	179_S	3.387	1.00
486_R	490_T	3.170	1.00
34_V	361_T	3.142	1.00
204_A	208_S	3.136	1.00
62_K	65_Q	3.022	1.00
194_D	197_S	2.929	1.00
431_E	435_S	2.928	1.00
207_R	220_Q	2.846	1.00
6_K	44_H	2.795	1.00
282_W	310_L	2.784	1.00
122_N	189_E	2.769	1.00
124_T	187_D	2.756	1.00
109_L	113_R	2.749	1.00
350_H	375_L	2.718	1.00
124_T	189_E	2.680	1.00
207_R	216_A	2.653	1.00
133_K	179_S	2.637	1.00
130_D	176_S	2.562	1.00
427_E	431_E	2.532	1.00
430_G	513_W	2.529	1.00
112_S	116_E	2.487	1.00
422_F	487_V	2.487	1.00
87_G	349_N	2.479	1.00
176_S	179_S	2.464	1.00
157_D	161_V	2.447	1.00
82_Q	86_A	2.429	1.00
130_D	133_K	2.421	1.00
158_N	162_C	2.384	1.00
39_Q	42_R	2.374	1.00
66_L	76_E	2.362	1.00
433_W	495_V	2.317	1.00
45_E	280_E	2.289	1.00
204_A	207_R	2.286	1.00
20_S	80_E	2.285	1.00
157_D	160_E	2.224	1.00
201_M	314_N	2.223	1.00
103_N	263_G	2.210	1.00
38_Y	42_R	2.209	1.00
36_V	46_V	2.202	1.00
132_E	181_A	2.183	1.00
207_R	224_E	2.144	1.00
421_T	450_D	2.137	1.00
430_G	434_E	2.130	1.00
89_N	498_K	2.114	1.00
203_Q	224_E	2.113	1.00
329_V	374_N	2.073	1.00
45_E	281_Y	2.069	1.00
213_E	216_A	2.063	1.00
285_D	319_S	2.060	1.00
158_N	161_V	2.048	1.00
113_R	117_N	2.047	1.00
154_Q	157_D	2.045	1.00
274_D	279_D	2.040	1.00
40_R	91_S	2.028	1.00
437_E	440_K	2.023	1.00
196_P	200_E	2.017	1.00
203_Q	220_Q	2.009	1.00
38_Y	430_G	2.007	1.00
492_L	500_T	1.993	1.00
275_S	279_D	1.989	1.00
426_A	491_Y	1.985	1.00
10_V	36_V	1.963	1.00
7_K	45_E	1.949	1.00
133_K	176_S	1.928	1.00
320_N	436_R	1.908	1.00
387_V	496_L	1.908	1.00
242_E	246_A	1.887	1.00
394_A	503_A	1.875	1.00
394_A	485_F	1.873	1.00
329_V	376_E	1.843	1.00
132_E	179_S	1.815	1.00
420_K	522_G	1.813	1.00
418_L	484_L	1.810	1.00
79_Q	82_Q	1.797	1.00
441_A	495_V	1.790	1.00
41_M	490_T	1.790	1.00
546_A	549_E	1.770	1.00
80_E	83_T	1.768	1.00
276_V	279_D	1.738	1.00
126_S	187_D	1.736	1.00
201_M	204_A	1.719	1.00
205_W	208_S	1.718	1.00
347_W	356_L	1.715	1.00
419_Y	483_N	1.714	1.00
39_Q	434_E	1.709	1.00
38_Y	434_E	1.704	1.00
346_T	349_N	1.695	1.00
536_D	540_V	1.689	1.00
205_W	311_E	1.682	1.00
432_A	444_E	1.660	1.00
194_D	229_Q	1.659	1.00
68_I	72_Q	1.657	1.00
415_D	455_Y	1.656	1.00
449_A	488_L	1.649	1.00
490_T	511_L	1.648	1.00
427_E	516_I	1.637	1.00
512_T	515_G	1.627	1.00
266_K	269_C	1.624	1.00
426_A	487_V	1.624	1.00
425_A	448_L	1.622	1.00
72_Q	76_E	1.598	1.00
54_A	99_H	1.596	1.00
345_S	349_N	1.591	1.00
421_T	424_D	1.586	1.00
572_T	575_D	1.581	1.00
444_E	447_A	1.579	1.00
420_K	424_D	1.569	1.00
217_N	221_E	1.562	1.00
37_R	497_P	1.536	1.00
216_A	220_Q	1.517	1.00
421_T	425_A	1.489	1.00
71_E	75_G	1.472	1.00
299_V	323_V	1.469	1.00
532_Y	536_D	1.455	1.00
432_A	440_K	1.454	1.00
422_F	426_A	1.454	1.00
424_D	428_V	1.448	1.00
422_F	484_L	1.446	1.00
146_C	170_E	1.445	1.00
387_V	499_L	1.432	1.00
114_L	312_G	1.424	1.00
423_T	426_A	1.412	1.00
175_K	182_T	1.410	1.00
131_P	181_A	1.408	1.00
452_A	484_L	1.401	1.00
517_Q	520_L	1.401	1.00
489_M	503_A	1.401	1.00
82_Q	95_Y	1.401	1.00
487_V	490_T	1.399	1.00
153_D	157_D	1.388	1.00
346_T	350_H	1.385	1.00
79_Q	83_T	1.377	1.00
110_I	313_S	1.375	1.00
154_Q	158_N	1.373	1.00
29_H	85_F	1.372	1.00
427_E	518_Q	1.351	1.00
42_R	434_E	1.348	1.00
487_V	491_Y	1.347	1.00
29_H	90_I	1.345	1.00
350_H	379_V	1.342	1.00
405_F	408_V	1.333	1.00
32_A	293_F	1.321	1.00
376_E	379_V	1.320	1.00
547_S	551_V	1.316	1.00
101_E	105_Q	1.314	1.00
96_H	102_E	1.312	1.00
433_W	441_A	1.310	1.00
424_D	522_G	1.307	1.00
201_M	311_E	1.305	1.00
72_Q	75_G	1.303	1.00
105_Q	270_D	1.299	1.00
176_S	181_A	1.297	1.00
143_K	177_V	1.296	1.00
220_Q	224_E	1.291	1.00
60_M	64_Q	1.290	1.00
128_L	185_M	1.288	1.00
117_N	314_N	1.287	1.00
412_E	415_D	1.271	1.00
460_A	463_V	1.269	1.00
41_M	493_K	1.269	1.00
245_N	248_G	1.264	1.00
146_C	172_I	1.264	1.00
401_I	482_I	1.263	1.00
197_S	200_E	1.263	1.00
558_V	561_P	1.260	1.00
119_F	198_F	1.258	1.00
66_L	69_T	1.252	1.00
428_V	431_E	1.250	1.00
462_W	477_I	1.248	1.00
486_R	509_T	1.246	1.00
52_D	82_Q	1.243	1.00
331_G	339_G	1.230	1.00
492_L	496_L	1.221	1.00
83_T	86_A	1.220	1.00
75_G	79_Q	1.217	1.00
210_A	320_N	1.216	1.00
5_A	45_E	1.212	1.00
426_A	430_G	1.211	1.00
425_A	444_E	1.208	1.00
126_S	185_M	1.200	1.00
120_I	232_I	1.200	1.00
561_P	564_D	1.198	1.00
199_S	203_Q	1.195	1.00
343_K	346_T	1.195	1.00
35_W	39_Q	1.187	1.00
501_E	505_A	1.183	1.00
540_V	544_V	1.179	1.00
274_D	277_S	1.174	1.00
28_E	324_H	1.171	1.00
83_T	87_G	1.170	1.00
119_F	197_S	1.162	1.00
78_S	97_S	1.159	1.00
144_G	175_K	1.154	1.00
489_M	500_T	1.153	1.00
130_D	181_A	1.145	1.00
429_I	491_Y	1.143	1.00
316_R	319_S	1.136	1.00
428_V	432_A	1.136	1.00
8_I	291_Y	1.133	1.00
564_D	569_E	1.130	1.00
97_S	100_S	1.126	1.00
36_V	91_S	1.126	1.00
422_F	448_L	1.123	1.00
49_I	264_S	1.123	1.00
564_D	567_I	1.119	1.00
114_L	309_M	1.119	1.00
291_Y	320_N	1.119	1.00
560_G	563_A	1.115	1.00
35_W	291_Y	1.115	1.00
465_A	468_E	1.112	1.00
525_V	528_F	1.112	1.00
537_M	557_P	1.111	1.00
539_Q	544_V	1.107	1.00
442_V	495_V	1.101	1.00
193_F	232_I	1.096	1.00
429_I	441_A	1.096	1.00
147_P	175_K	1.090	1.00
76_E	79_Q	1.083	1.00
87_G	345_S	1.082	1.00
562_L	565_D	1.078	1.00
413_L	416_P	1.076	1.00
107_S	251_F	1.073	1.00
405_F	475_Q	1.064	1.00
8_I	35_W	1.063	1.00
561_P	565_D	1.063	1.00
476_A	480_M	1.062	1.00
459_Q	477_I	1.060	1.00
150_K	154_Q	1.052	1.00
474_L	478_C	1.050	1.00
445_I	492_L	1.049	1.00
21_I	25_H	1.049	1.00
241_F	256_D	1.049	1.00
564_D	568_Q	1.049	1.00
573_F	576_F	1.044	1.00
425_A	429_I	1.043	1.00
416_P	522_G	1.043	1.00
125_I	192_F	1.039	1.00
103_N	260_G	1.038	1.00
203_Q	207_R	1.036	1.00
132_E	176_S	1.035	1.00
303_S	321_L	1.031	1.00
423_T	427_E	1.029	1.00
539_Q	543_L	1.026	1.00
34_V	433_W	1.024	1.00
565_D	568_Q	1.024	1.00
358_Y	442_V	1.021	1.00
536_D	544_V	1.020	1.00
425_A	491_Y	1.019	1.00
419_Y	520_L	1.018	1.00
393_L	452_A	1.016	1.00
421_T	451_L	1.013	1.00
12_C	48_F	1.013	1.00
62_K	66_L	1.013	1.00
432_A	435_S	1.012	1.00
85_F	90_I	1.011	1.00
232_I	251_F	1.009	1.00
7_K	280_E	1.006	1.00
78_S	82_Q	1.000	1.00
358_Y	496_L	0.992	1.00
466_K	473_D	0.990	1.00
327_V	371_I	0.989	1.00
131_P	184_V	0.983	1.00
106_L	109_L	0.982	1.00
128_L	142_V	0.982	1.00
101_E	104_R	0.981	1.00
359_Y	381_R	0.980	1.00
524_K	540_V	0.977	1.00
536_D	539_Q	0.977	1.00
215_V	323_V	0.976	1.00
261_Y	310_L	0.970	1.00
30_I	34_V	0.970	1.00
568_Q	572_T	0.967	1.00
150_K	153_D	0.966	1.00
121_K	194_D	0.965	1.00
105_Q	108_E	0.963	1.00
496_L	499_L	0.962	1.00
559_T	562_L	0.961	1.00
258_P	309_M	0.959	1.00
536_D	543_L	0.959	1.00
294_I	303_S	0.958	1.00
483_N	487_V	0.957	1.00
133_K	181_A	0.956	1.00
418_L	451_L	0.956	1.00
429_I	445_I	0.952	1.00
200_E	203_Q	0.951	1.00
235_D	249_K	0.949	1.00
415_D	476_A	0.947	1.00
76_E	80_E	0.946	1.00
480_M	484_L	0.945	1.00
42_R	515_G	0.941	1.00
493_K	500_T	0.941	1.00
544_V	547_S	0.940	1.00
42_R	513_W	0.939	1.00
261_Y	282_W	0.939	1.00
565_D	572_T	0.938	1.00
416_P	420_K	0.934	1.00
568_Q	571_I	0.932	1.00
144_G	172_I	0.931	1.00
8_I	39_Q	0.931	1.00
557_P	560_G	0.931	1.00
412_E	473_D	0.925	1.00
144_G	174_P	0.922	1.00
12_C	32_A	0.917	1.00
571_I	575_D	0.917	1.00
557_P	561_P	0.916	1.00
559_T	563_A	0.915	1.00
175_K	180_G	0.915	1.00
531_L	534_R	0.913	1.00
362_A	442_V	0.911	1.00
107_S	241_F	0.909	1.00
418_L	448_L	0.909	1.00
73_M	77_M	0.908	1.00
75_G	99_H	0.906	1.00
23_L	327_V	0.906	1.00
432_A	441_A	0.905	1.00
193_F	255_L	0.903	1.00
522_G	526_N	0.902	1.00
208_S	315_F	0.900	1.00
67_G	70_P	0.895	1.00
221_E	224_E	0.895	1.00
524_K	528_F	0.895	1.00
23_L	341_F	0.895	1.00
35_W	438_F	0.893	1.00
531_L	536_D	0.890	1.00
217_N	220_Q	0.890	1.00
277_S	280_E	0.890	1.00
430_G	515_G	0.890	1.00
516_I	521_L	0.887	1.00
269_C	275_S	0.886	1.00
169_T	173_E	0.886	1.00
20_S	84_D	0.882	1.00
12_C	29_H	0.881	1.00
443_R	447_A	0.878	1.00
429_I	444_E	0.876	1.00
12_C	92_Y	0.874	1.00
4_V	45_E	0.874	1.00
482_I	486_R	0.873	1.00
223_F	307_P	0.873	1.00
419_Y	480_M	0.872	1.00
26_M	88_F	0.871	1.00
151_S	155_Y	0.867	1.00
77_M	80_E	0.866	1.00
396_R	459_Q	0.861	1.00
529_K	539_Q	0.860	1.00
560_G	564_D	0.860	1.00
545_E	548_K	0.859	1.00
533_N	536_D	0.858	1.00
529_K	536_D	0.858	1.00
564_D	575_D	0.857	1.00
160_E	165_T	0.855	1.00
38_Y	433_W	0.853	1.00
473_D	476_A	0.852	1.00
516_I	519_P	0.850	1.00
223_F	304_L	0.849	1.00
291_Y	322_F	0.848	1.00
528_F	536_D	0.847	1.00
36_V	40_R	0.845	1.00
211_L	219_M	0.844	1.00
145_T	175_K	0.842	1.00
465_A	474_L	0.841	1.00
390_V	489_M	0.840	1.00
52_D	95_Y	0.837	1.00
334_M	341_F	0.836	1.00
121_K	229_Q	0.836	1.00
108_E	112_S	0.833	1.00
426_A	514_D	0.830	1.00
428_V	440_K	0.830	1.00
570_T	573_F	0.829	1.00
111_Y	251_F	0.827	1.00
85_F	92_Y	0.827	1.00
404_R	478_C	0.826	1.00
297_D	326_Y	0.824	1.00
530_A	534_R	0.823	1.00
203_Q	223_F	0.819	0.99
83_T	345_S	0.817	0.99
518_Q	521_L	0.816	0.99
14_L	103_N	0.815	0.99
528_F	532_Y	0.814	0.99
457_D	460_A	0.810	0.99
537_M	540_V	0.809	0.99
537_M	541_E	0.806	0.99
87_G	348_L	0.805	0.99
35_W	436_R	0.804	0.99
423_T	521_L	0.804	0.99
196_P	229_Q	0.800	0.99
545_E	549_E	0.800	0.99
527_P	531_L	0.800	0.99
532_Y	535_I	0.798	0.99
567_I	570_T	0.797	0.99
489_M	504_E	0.797	0.99
473_D	477_I	0.796	0.99
275_S	278_F	0.796	0.99
536_D	548_K	0.795	0.99
565_D	573_F	0.795	0.99
548_K	551_V	0.793	0.99
565_D	570_T	0.792	0.99
390_V	488_L	0.790	0.99
523_H	526_N	0.790	0.99
279_D	283_K	0.787	0.99
30_I	361_T	0.786	0.99
96_H	103_N	0.785	0.99
291_Y	436_R	0.785	0.99
348_L	353_A	0.785	0.99
557_P	562_L	0.779	0.99
269_C	274_D	0.779	0.99
94_N	102_E	0.779	0.99
541_E	544_V	0.779	0.99
395_S	398_A	0.779	0.99
563_A	568_Q	0.778	0.99
31_Q	293_F	0.778	0.99
560_G	565_D	0.776	0.99
106_L	266_K	0.774	0.99
541_E	550_E	0.774	0.99
180_G	338_R	0.772	0.99
390_V	503_A	0.772	0.99
40_R	46_V	0.771	0.99
27_L	371_I	0.770	0.99
522_G	525_V	0.768	0.99
551_V	572_T	0.767	0.99
334_M	340_T	0.766	0.99
522_G	536_D	0.764	0.99
529_K	533_N	0.763	0.99
150_K	172_I	0.763	0.99
48_F	92_Y	0.762	0.99
11_T	260_G	0.762	0.99
504_E	511_L	0.761	0.99
542_A	546_A	0.761	0.99
417_Q	421_T	0.760	0.99
190_H	231_D	0.759	0.99
423_T	518_Q	0.759	0.99
552_K	557_P	0.756	0.99
56_G	60_M	0.754	0.99
201_M	205_W	0.753	0.99
63_A	70_P	0.752	0.99
102_E	270_D	0.752	0.99
125_I	231_D	0.751	0.99
454_R	458_E	0.750	0.99
180_G	337_S	0.749	0.99
462_W	473_D	0.748	0.99
547_S	576_F	0.748	0.99
431_E	434_E	0.747	0.99
242_E	248_G	0.746	0.99
465_A	473_D	0.746	0.99
391_V	499_L	0.746	0.99
362_A	381_R	0.746	0.99
127_Q	136_F	0.745	0.99
424_D	427_E	0.745	0.99
396_R	400_F	0.744	0.99
467_Q	473_D	0.743	0.99
393_L	456_V	0.742	0.99
421_T	526_N	0.742	0.99
107_S	256_D	0.741	0.99
535_I	538_R	0.740	0.99
502_R	505_A	0.740	0.99
145_T	180_G	0.738	0.99
6_K	39_Q	0.738	0.99
328_T	372_D	0.737	0.99
423_T	520_L	0.736	0.99
529_K	532_Y	0.735	0.99
68_I	76_E	0.734	0.99
110_I	255_L	0.732	0.99
160_E	163_G	0.731	0.99
562_L	566_P	0.731	0.99
34_V	495_V	0.729	0.99
393_L	449_A	0.728	0.99
511_L	514_D	0.727	0.99
373_L	378_F	0.726	0.99
558_V	564_D	0.725	0.99
5_A	44_H	0.725	0.99
112_S	115_K	0.725	0.99
498_K	502_R	0.725	0.99
569_E	573_F	0.724	0.99
110_I	259_I	0.723	0.99
541_E	545_E	0.721	0.99
569_E	572_T	0.721	0.99
552_K	558_V	0.719	0.99
202_L	308_A	0.717	0.99
564_D	572_T	0.717	0.99
375_L	379_V	0.717	0.99
419_Y	423_T	0.717	0.99
561_P	568_Q	0.717	0.99
545_E	550_E	0.717	0.99
282_W	315_F	0.715	0.99
306_W	318_P	0.715	0.99
346_T	375_L	0.715	0.99
522_G	528_F	0.714	0.99
12_C	85_F	0.714	0.99
205_W	316_R	0.713	0.99
426_A	516_I	0.710	0.99
276_V	280_E	0.709	0.99
397_N	481_G	0.709	0.99
155_Y	158_N	0.708	0.99
536_D	541_E	0.707	0.99
118_G	194_D	0.705	0.98
572_T	576_F	0.702	0.98
136_F	231_D	0.701	0.98
549_E	552_K	0.698	0.98
41_M	512_T	0.698	0.98
493_K	504_E	0.698	0.98
31_Q	361_T	0.698	0.98
493_K	501_E	0.698	0.98
205_W	209_G	0.697	0.98
425_A	428_V	0.697	0.98
540_V	543_L	0.697	0.98
565_D	575_D	0.696	0.98
420_K	423_T	0.693	0.98
445_I	491_Y	0.692	0.98
8_I	436_R	0.692	0.98
445_I	488_L	0.691	0.98
538_R	542_A	0.691	0.98
160_E	168_P	0.690	0.98
75_G	97_S	0.689	0.98
544_V	549_E	0.688	0.98
206_T	220_Q	0.688	0.98
533_N	539_Q	0.687	0.98
398_A	402_N	0.685	0.98
111_Y	120_I	0.684	0.98
571_I	576_F	0.684	0.98
475_Q	478_C	0.682	0.98
142_V	183_P	0.682	0.98
133_K	180_G	0.680	0.98
420_K	521_L	0.678	0.98
7_K	285_D	0.677	0.98
32_A	48_F	0.676	0.98
561_P	572_T	0.676	0.98
423_T	517_Q	0.676	0.98
9_L	265_F	0.676	0.98
557_P	564_D	0.676	0.98
566_P	573_F	0.675	0.98
526_N	530_A	0.675	0.98
528_F	540_V	0.675	0.98
423_T	516_I	0.675	0.98
7_K	281_Y	0.675	0.98
105_Q	109_L	0.672	0.98
415_D	480_M	0.671	0.98
311_E	316_R	0.671	0.98
253_V	256_D	0.670	0.98
331_G	372_D	0.669	0.98
571_I	574_D	0.669	0.98
539_Q	550_E	0.667	0.98
364_L	371_I	0.667	0.98
145_T	173_E	0.667	0.98
419_Y	484_L	0.666	0.98
338_R	341_F	0.665	0.98
464_V	474_L	0.665	0.98
94_N	100_S	0.664	0.98
296_K	326_Y	0.663	0.98
564_D	571_I	0.663	0.98
9_L	285_D	0.662	0.98
544_V	548_K	0.662	0.98
570_T	574_D	0.661	0.98
557_P	576_F	0.660	0.98
209_G	316_R	0.659	0.98
304_L	308_A	0.658	0.98
422_F	480_M	0.658	0.98
432_A	437_E	0.658	0.98
559_T	564_D	0.657	0.98
440_K	444_E	0.657	0.98
218_K	221_E	0.656	0.98
429_I	433_W	0.656	0.98
566_P	569_E	0.655	0.98
384_A	388_N	0.654	0.98
559_T	569_E	0.652	0.97
526_N	529_K	0.652	0.97
135_M	179_S	0.651	0.97
415_D	462_W	0.651	0.97
420_K	526_N	0.651	0.97
561_P	573_F	0.649	0.97
11_T	284_K	0.649	0.97
543_L	546_A	0.649	0.97
418_L	480_M	0.648	0.97
115_K	120_I	0.647	0.97
259_I	309_M	0.647	0.97
47_N	281_Y	0.647	0.97
377_D	380_Q	0.646	0.97
202_L	205_W	0.645	0.97
84_D	343_K	0.643	0.97
68_I	73_M	0.641	0.97
361_T	495_V	0.641	0.97
329_V	375_L	0.640	0.97
413_L	528_F	0.640	0.97
123_R	192_F	0.639	0.97
543_L	548_K	0.639	0.97
198_F	312_G	0.639	0.97
477_I	480_M	0.639	0.97
464_V	477_I	0.637	0.97
96_H	260_G	0.636	0.97
390_V	499_L	0.636	0.97
394_A	398_A	0.636	0.97
502_R	506_F	0.636	0.97
54_A	97_S	0.635	0.97
533_N	537_M	0.634	0.97
129_Y	134_G	0.632	0.97
485_F	507_L	0.632	0.97
41_M	494_P	0.632	0.97
504_E	508_N	0.632	0.97
58_P	178_V	0.631	0.97
20_S	343_K	0.628	0.97
414_A	459_Q	0.627	0.97
516_I	520_L	0.626	0.97
403_K	478_C	0.626	0.97
465_A	469_G	0.626	0.97
215_V	218_K	0.624	0.97
328_T	370_D	0.623	0.97
560_G	566_P	0.623	0.97
562_L	567_I	0.620	0.97
533_N	540_V	0.619	0.97
535_I	539_Q	0.616	0.96
329_V	332_A	0.616	0.96
563_A	566_P	0.615	0.96
168_P	171_L	0.615	0.96
149_C	152_P	0.614	0.96
412_E	476_A	0.613	0.96
558_V	566_P	0.612	0.96
195_L	198_F	0.612	0.96
61_L	65_Q	0.612	0.96
427_E	521_L	0.612	0.96
527_P	530_A	0.611	0.96
406_D	409_L	0.610	0.96
361_T	442_V	0.609	0.96
130_D	137_L	0.609	0.96
211_L	320_N	0.609	0.96
114_L	117_N	0.607	0.96
393_L	485_F	0.607	0.96
486_R	508_N	0.607	0.96
484_L	487_V	0.607	0.96
440_K	443_R	0.606	0.96
153_D	160_E	0.606	0.96
358_Y	381_R	0.606	0.96
94_N	267_N	0.605	0.96
27_L	327_V	0.605	0.96
412_E	462_W	0.605	0.96
424_D	526_N	0.604	0.96
408_V	411_S	0.603	0.96
486_R	504_E	0.602	0.96
543_L	547_S	0.601	0.96
568_Q	573_F	0.600	0.96
29_H	92_Y	0.599	0.96
211_L	321_L	0.599	0.96
562_L	568_Q	0.599	0.96
202_L	307_P	0.599	0.96
28_E	32_A	0.598	0.96
526_N	538_R	0.598	0.96
390_V	492_L	0.598	0.96
359_Y	377_D	0.598	0.96
529_K	543_L	0.597	0.96
523_H	527_P	0.596	0.96
459_Q	473_D	0.595	0.96
529_K	544_V	0.594	0.96
148_K	151_S	0.594	0.96
50_C	94_N	0.592	0.96
390_V	449_A	0.592	0.96
542_A	545_E	0.592	0.96
37_R	91_S	0.591	0.96
195_L	227_L	0.590	0.95
262_M	282_W	0.590	0.95
31_Q	438_F	0.588	0.95
251_F	255_L	0.587	0.95
524_K	527_P	0.587	0.95
214_Q	296_K	0.586	0.95
210_A	216_A	0.586	0.95
213_E	217_N	0.584	0.95
406_D	410_A	0.583	0.95
525_V	529_K	0.583	0.95
137_L	183_P	0.580	0.95
322_F	436_R	0.579	0.95
538_R	541_E	0.578	0.95
563_A	569_E	0.577	0.95
315_F	319_S	0.577	0.95
513_W	516_I	0.577	0.95
265_F	282_W	0.576	0.95
504_E	509_T	0.576	0.95
206_T	223_F	0.575	0.95
307_P	316_R	0.575	0.95
158_N	164_A	0.575	0.95
6_K	45_E	0.574	0.95
39_Q	46_V	0.574	0.95
534_R	538_R	0.574	0.95
196_P	199_S	0.573	0.95
564_D	570_T	0.573	0.95
84_D	345_S	0.572	0.95
544_V	550_E	0.572	0.95
539_Q	542_A	0.572	0.95
416_P	419_Y	0.571	0.95
64_Q	70_P	0.571	0.95
145_T	174_P	0.571	0.95
138_P	141_F	0.570	0.95
389_K	449_A	0.570	0.95
266_K	277_S	0.569	0.95
128_L	183_P	0.568	0.94
123_R	229_Q	0.568	0.94
266_K	270_D	0.568	0.94
280_E	283_K	0.568	0.94
261_Y	309_M	0.567	0.94
195_L	308_A	0.567	0.94
198_F	314_N	0.566	0.94
65_Q	339_G	0.566	0.94
202_L	304_L	0.566	0.94
550_E	574_D	0.566	0.94
168_P	173_E	0.566	0.94
104_R	242_E	0.565	0.94
418_L	455_Y	0.565	0.94
557_P	563_A	0.565	0.94
530_A	533_N	0.564	0.94
569_E	575_D	0.564	0.94
19_G	25_H	0.563	0.94
52_D	78_S	0.563	0.94
311_E	314_N	0.563	0.94
127_Q	137_L	0.563	0.94
110_I	114_L	0.563	0.94
137_L	176_S	0.561	0.94
120_I	193_F	0.559	0.94
422_F	425_A	0.557	0.94
395_S	506_F	0.557	0.94
559_T	565_D	0.556	0.94
278_F	282_W	0.556	0.94
347_W	373_L	0.555	0.94
421_T	448_L	0.555	0.94
560_G	573_F	0.554	0.94
56_G	70_P	0.554	0.94
557_P	575_D	0.554	0.94
565_D	569_E	0.553	0.94
9_L	281_Y	0.553	0.94
377_D	381_R	0.552	0.94
341_F	344_A	0.550	0.93
172_I	175_K	0.550	0.93
62_K	73_M	0.549	0.93
466_K	474_L	0.549	0.93
475_Q	479_S	0.549	0.93
96_H	264_S	0.548	0.93
426_A	429_I	0.546	0.93
559_T	566_P	0.546	0.93
156_G	163_G	0.546	0.93
479_S	483_N	0.545	0.93
565_D	576_F	0.545	0.93
347_W	375_L	0.545	0.93
75_G	100_S	0.544	0.93
566_P	570_T	0.544	0.93
526_N	540_V	0.544	0.93
21_I	81_H	0.544	0.93
499_L	502_R	0.544	0.93
400_F	478_C	0.544	0.93
563_A	567_I	0.544	0.93
407_G	410_A	0.544	0.93
62_K	337_S	0.543	0.93
534_R	537_M	0.543	0.93
568_Q	576_F	0.543	0.93
300_Y	304_L	0.542	0.93
558_V	565_D	0.541	0.93
563_A	570_T	0.540	0.93
156_G	160_E	0.540	0.93
74_I	78_S	0.539	0.93
414_A	417_Q	0.539	0.93
546_A	551_V	0.539	0.93
292_H	306_W	0.538	0.93
562_L	569_E	0.537	0.93
219_M	321_L	0.536	0.93
528_F	539_Q	0.535	0.93
517_Q	521_L	0.534	0.92
113_R	313_S	0.534	0.92
564_D	576_F	0.533	0.92
179_S	182_T	0.533	0.92
267_N	270_D	0.532	0.92
417_Q	451_L	0.532	0.92
190_H	235_D	0.530	0.92
412_E	459_Q	0.528	0.92
334_M	339_G	0.528	0.92
106_L	263_G	0.528	0.92
448_L	491_Y	0.528	0.92
564_D	573_F	0.527	0.92
496_L	500_T	0.527	0.92
206_T	209_G	0.527	0.92
192_F	231_D	0.527	0.92
293_F	324_H	0.526	0.92
417_Q	420_K	0.526	0.92
484_L	488_L	0.526	0.92
96_H	100_S	0.526	0.92
415_D	477_I	0.525	0.92
114_L	193_F	0.525	0.92
71_E	100_S	0.525	0.92
191_F	246_A	0.524	0.92
209_G	216_A	0.524	0.92
115_K	245_N	0.523	0.92
89_N	353_A	0.522	0.92
532_Y	539_Q	0.522	0.92
120_I	251_F	0.521	0.92
560_G	567_I	0.521	0.92
28_E	293_F	0.520	0.91
232_I	243_I	0.519	0.91
407_G	411_S	0.519	0.91
451_L	454_R	0.518	0.91
376_E	380_Q	0.517	0.91
459_Q	462_W	0.517	0.91
536_D	542_A	0.517	0.91
423_T	487_V	0.516	0.91
159_C	164_A	0.515	0.91
561_P	567_I	0.514	0.91
558_V	563_A	0.514	0.91
66_L	73_M	0.513	0.91
513_W	517_Q	0.512	0.91
262_M	310_L	0.512	0.91
401_I	478_C	0.512	0.91
295_G	326_Y	0.511	0.91
5_A	512_T	0.510	0.91
497_P	500_T	0.507	0.90
546_A	550_E	0.506	0.90
560_G	569_E	0.506	0.90
505_A	509_T	0.505	0.90
295_G	324_H	0.505	0.90
558_V	572_T	0.504	0.90
125_I	188_S	0.504	0.90
215_V	296_K	0.504	0.90
104_R	108_E	0.504	0.90
148_K	164_A	0.503	0.90
392_N	396_R	0.503	0.90
394_A	397_N	0.503	0.90
456_V	481_G	0.502	0.90
21_I	84_D	0.501	0.90
563_A	572_T	0.501	0.90
570_T	575_D	0.501	0.90
265_F	277_S	0.500	0.90
536_D	547_S	0.500	0.90

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1rqgA	2	0.8139	100	0.187	Contact Map
1gaxA	1	0.9306	100	0.282	Contact Map
1ffyA	1	0.9069	100	0.305	Contact Map
1ileA	1	0.7888	100	0.326	Contact Map
3h99A	1	0.8021	100	0.357	Contact Map
1wz2A	1	0.9247	100	0.36	Contact Map
3kflA	1	0.7459	100	0.369	Contact Map
3ziuA	1	0.7489	100	0.382	Contact Map
4qreA	1	0.74	100	0.388	Contact Map
4arcA	1	0.7386	100	0.394	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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