GREMLIN Database
SYM - Methionine--tRNA ligase
UniProt: P00959 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10586
Length: 677 (553)
Sequences: 13197 (6586)
Seq/√Len: 280.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
39_Q44_H5.9001.00
332_A338_R3.8471.00
200_E204_A3.7821.00
428_V444_E3.6661.00
117_N312_G3.6431.00
69_T72_Q3.5581.00
113_R116_E3.5541.00
42_R430_G3.5041.00
130_D179_S3.3871.00
486_R490_T3.1701.00
34_V361_T3.1421.00
204_A208_S3.1361.00
62_K65_Q3.0221.00
194_D197_S2.9291.00
431_E435_S2.9281.00
207_R220_Q2.8461.00
6_K44_H2.7951.00
282_W310_L2.7841.00
122_N189_E2.7691.00
124_T187_D2.7561.00
109_L113_R2.7491.00
350_H375_L2.7181.00
124_T189_E2.6801.00
207_R216_A2.6531.00
133_K179_S2.6371.00
130_D176_S2.5621.00
427_E431_E2.5321.00
430_G513_W2.5291.00
112_S116_E2.4871.00
422_F487_V2.4871.00
87_G349_N2.4791.00
176_S179_S2.4641.00
157_D161_V2.4471.00
82_Q86_A2.4291.00
130_D133_K2.4211.00
158_N162_C2.3841.00
39_Q42_R2.3741.00
66_L76_E2.3621.00
433_W495_V2.3171.00
45_E280_E2.2891.00
204_A207_R2.2861.00
20_S80_E2.2851.00
157_D160_E2.2241.00
201_M314_N2.2231.00
103_N263_G2.2101.00
38_Y42_R2.2091.00
36_V46_V2.2021.00
132_E181_A2.1831.00
207_R224_E2.1441.00
421_T450_D2.1371.00
430_G434_E2.1301.00
89_N498_K2.1141.00
203_Q224_E2.1131.00
329_V374_N2.0731.00
45_E281_Y2.0691.00
213_E216_A2.0631.00
285_D319_S2.0601.00
158_N161_V2.0481.00
113_R117_N2.0471.00
154_Q157_D2.0451.00
274_D279_D2.0401.00
40_R91_S2.0281.00
437_E440_K2.0231.00
196_P200_E2.0171.00
203_Q220_Q2.0091.00
38_Y430_G2.0071.00
492_L500_T1.9931.00
275_S279_D1.9891.00
426_A491_Y1.9851.00
10_V36_V1.9631.00
7_K45_E1.9491.00
133_K176_S1.9281.00
320_N436_R1.9081.00
387_V496_L1.9081.00
242_E246_A1.8871.00
394_A503_A1.8751.00
394_A485_F1.8731.00
329_V376_E1.8431.00
132_E179_S1.8151.00
420_K522_G1.8131.00
418_L484_L1.8101.00
79_Q82_Q1.7971.00
441_A495_V1.7901.00
41_M490_T1.7901.00
546_A549_E1.7701.00
80_E83_T1.7681.00
276_V279_D1.7381.00
126_S187_D1.7361.00
201_M204_A1.7191.00
205_W208_S1.7181.00
347_W356_L1.7151.00
419_Y483_N1.7141.00
39_Q434_E1.7091.00
38_Y434_E1.7041.00
346_T349_N1.6951.00
536_D540_V1.6891.00
205_W311_E1.6821.00
432_A444_E1.6601.00
194_D229_Q1.6591.00
68_I72_Q1.6571.00
415_D455_Y1.6561.00
449_A488_L1.6491.00
490_T511_L1.6481.00
427_E516_I1.6371.00
512_T515_G1.6271.00
266_K269_C1.6241.00
426_A487_V1.6241.00
425_A448_L1.6221.00
72_Q76_E1.5981.00
54_A99_H1.5961.00
345_S349_N1.5911.00
421_T424_D1.5861.00
572_T575_D1.5811.00
444_E447_A1.5791.00
420_K424_D1.5691.00
217_N221_E1.5621.00
37_R497_P1.5361.00
216_A220_Q1.5171.00
421_T425_A1.4891.00
71_E75_G1.4721.00
299_V323_V1.4691.00
532_Y536_D1.4551.00
432_A440_K1.4541.00
422_F426_A1.4541.00
424_D428_V1.4481.00
422_F484_L1.4461.00
146_C170_E1.4451.00
387_V499_L1.4321.00
114_L312_G1.4241.00
423_T426_A1.4121.00
175_K182_T1.4101.00
131_P181_A1.4081.00
452_A484_L1.4011.00
517_Q520_L1.4011.00
489_M503_A1.4011.00
82_Q95_Y1.4011.00
487_V490_T1.3991.00
153_D157_D1.3881.00
346_T350_H1.3851.00
79_Q83_T1.3771.00
110_I313_S1.3751.00
154_Q158_N1.3731.00
29_H85_F1.3721.00
427_E518_Q1.3511.00
42_R434_E1.3481.00
487_V491_Y1.3471.00
29_H90_I1.3451.00
350_H379_V1.3421.00
405_F408_V1.3331.00
32_A293_F1.3211.00
376_E379_V1.3201.00
547_S551_V1.3161.00
101_E105_Q1.3141.00
96_H102_E1.3121.00
433_W441_A1.3101.00
424_D522_G1.3071.00
201_M311_E1.3051.00
72_Q75_G1.3031.00
105_Q270_D1.2991.00
176_S181_A1.2971.00
143_K177_V1.2961.00
220_Q224_E1.2911.00
60_M64_Q1.2901.00
128_L185_M1.2881.00
117_N314_N1.2871.00
412_E415_D1.2711.00
460_A463_V1.2691.00
41_M493_K1.2691.00
245_N248_G1.2641.00
146_C172_I1.2641.00
401_I482_I1.2631.00
197_S200_E1.2631.00
558_V561_P1.2601.00
119_F198_F1.2581.00
66_L69_T1.2521.00
428_V431_E1.2501.00
462_W477_I1.2481.00
486_R509_T1.2461.00
52_D82_Q1.2431.00
331_G339_G1.2301.00
492_L496_L1.2211.00
83_T86_A1.2201.00
75_G79_Q1.2171.00
210_A320_N1.2161.00
5_A45_E1.2121.00
426_A430_G1.2111.00
425_A444_E1.2081.00
126_S185_M1.2001.00
120_I232_I1.2001.00
561_P564_D1.1981.00
199_S203_Q1.1951.00
343_K346_T1.1951.00
35_W39_Q1.1871.00
501_E505_A1.1831.00
540_V544_V1.1791.00
274_D277_S1.1741.00
28_E324_H1.1711.00
83_T87_G1.1701.00
119_F197_S1.1621.00
78_S97_S1.1591.00
144_G175_K1.1541.00
489_M500_T1.1531.00
130_D181_A1.1451.00
429_I491_Y1.1431.00
316_R319_S1.1361.00
428_V432_A1.1361.00
8_I291_Y1.1331.00
564_D569_E1.1301.00
97_S100_S1.1261.00
36_V91_S1.1261.00
422_F448_L1.1231.00
49_I264_S1.1231.00
564_D567_I1.1191.00
114_L309_M1.1191.00
291_Y320_N1.1191.00
560_G563_A1.1151.00
35_W291_Y1.1151.00
465_A468_E1.1121.00
525_V528_F1.1121.00
537_M557_P1.1111.00
539_Q544_V1.1071.00
442_V495_V1.1011.00
193_F232_I1.0961.00
429_I441_A1.0961.00
147_P175_K1.0901.00
76_E79_Q1.0831.00
87_G345_S1.0821.00
562_L565_D1.0781.00
413_L416_P1.0761.00
107_S251_F1.0731.00
405_F475_Q1.0641.00
8_I35_W1.0631.00
561_P565_D1.0631.00
476_A480_M1.0621.00
459_Q477_I1.0601.00
150_K154_Q1.0521.00
474_L478_C1.0501.00
445_I492_L1.0491.00
21_I25_H1.0491.00
241_F256_D1.0491.00
564_D568_Q1.0491.00
573_F576_F1.0441.00
425_A429_I1.0431.00
416_P522_G1.0431.00
125_I192_F1.0391.00
103_N260_G1.0381.00
203_Q207_R1.0361.00
132_E176_S1.0351.00
303_S321_L1.0311.00
423_T427_E1.0291.00
539_Q543_L1.0261.00
34_V433_W1.0241.00
565_D568_Q1.0241.00
358_Y442_V1.0211.00
536_D544_V1.0201.00
425_A491_Y1.0191.00
419_Y520_L1.0181.00
393_L452_A1.0161.00
421_T451_L1.0131.00
12_C48_F1.0131.00
62_K66_L1.0131.00
432_A435_S1.0121.00
85_F90_I1.0111.00
232_I251_F1.0091.00
7_K280_E1.0061.00
78_S82_Q1.0001.00
358_Y496_L0.9921.00
466_K473_D0.9901.00
327_V371_I0.9891.00
131_P184_V0.9831.00
106_L109_L0.9821.00
128_L142_V0.9821.00
101_E104_R0.9811.00
359_Y381_R0.9801.00
524_K540_V0.9771.00
536_D539_Q0.9771.00
215_V323_V0.9761.00
261_Y310_L0.9701.00
30_I34_V0.9701.00
568_Q572_T0.9671.00
150_K153_D0.9661.00
121_K194_D0.9651.00
105_Q108_E0.9631.00
496_L499_L0.9621.00
559_T562_L0.9611.00
258_P309_M0.9591.00
536_D543_L0.9591.00
294_I303_S0.9581.00
483_N487_V0.9571.00
133_K181_A0.9561.00
418_L451_L0.9561.00
429_I445_I0.9521.00
200_E203_Q0.9511.00
235_D249_K0.9491.00
415_D476_A0.9471.00
76_E80_E0.9461.00
480_M484_L0.9451.00
42_R515_G0.9411.00
493_K500_T0.9411.00
544_V547_S0.9401.00
42_R513_W0.9391.00
261_Y282_W0.9391.00
565_D572_T0.9381.00
416_P420_K0.9341.00
568_Q571_I0.9321.00
144_G172_I0.9311.00
8_I39_Q0.9311.00
557_P560_G0.9311.00
412_E473_D0.9251.00
144_G174_P0.9221.00
12_C32_A0.9171.00
571_I575_D0.9171.00
557_P561_P0.9161.00
559_T563_A0.9151.00
175_K180_G0.9151.00
531_L534_R0.9131.00
362_A442_V0.9111.00
107_S241_F0.9091.00
418_L448_L0.9091.00
73_M77_M0.9081.00
75_G99_H0.9061.00
23_L327_V0.9061.00
432_A441_A0.9051.00
193_F255_L0.9031.00
522_G526_N0.9021.00
208_S315_F0.9001.00
67_G70_P0.8951.00
221_E224_E0.8951.00
524_K528_F0.8951.00
23_L341_F0.8951.00
35_W438_F0.8931.00
531_L536_D0.8901.00
217_N220_Q0.8901.00
277_S280_E0.8901.00
430_G515_G0.8901.00
516_I521_L0.8871.00
269_C275_S0.8861.00
169_T173_E0.8861.00
20_S84_D0.8821.00
12_C29_H0.8811.00
443_R447_A0.8781.00
429_I444_E0.8761.00
12_C92_Y0.8741.00
4_V45_E0.8741.00
482_I486_R0.8731.00
223_F307_P0.8731.00
419_Y480_M0.8721.00
26_M88_F0.8711.00
151_S155_Y0.8671.00
77_M80_E0.8661.00
396_R459_Q0.8611.00
529_K539_Q0.8601.00
560_G564_D0.8601.00
545_E548_K0.8591.00
533_N536_D0.8581.00
529_K536_D0.8581.00
564_D575_D0.8571.00
160_E165_T0.8551.00
38_Y433_W0.8531.00
473_D476_A0.8521.00
516_I519_P0.8501.00
223_F304_L0.8491.00
291_Y322_F0.8481.00
528_F536_D0.8471.00
36_V40_R0.8451.00
211_L219_M0.8441.00
145_T175_K0.8421.00
465_A474_L0.8411.00
390_V489_M0.8401.00
52_D95_Y0.8371.00
334_M341_F0.8361.00
121_K229_Q0.8361.00
108_E112_S0.8331.00
426_A514_D0.8301.00
428_V440_K0.8301.00
570_T573_F0.8291.00
111_Y251_F0.8271.00
85_F92_Y0.8271.00
404_R478_C0.8261.00
297_D326_Y0.8241.00
530_A534_R0.8231.00
203_Q223_F0.8190.99
83_T345_S0.8170.99
518_Q521_L0.8160.99
14_L103_N0.8150.99
528_F532_Y0.8140.99
457_D460_A0.8100.99
537_M540_V0.8090.99
537_M541_E0.8060.99
87_G348_L0.8050.99
35_W436_R0.8040.99
423_T521_L0.8040.99
196_P229_Q0.8000.99
545_E549_E0.8000.99
527_P531_L0.8000.99
532_Y535_I0.7980.99
567_I570_T0.7970.99
489_M504_E0.7970.99
473_D477_I0.7960.99
275_S278_F0.7960.99
536_D548_K0.7950.99
565_D573_F0.7950.99
548_K551_V0.7930.99
565_D570_T0.7920.99
390_V488_L0.7900.99
523_H526_N0.7900.99
279_D283_K0.7870.99
30_I361_T0.7860.99
96_H103_N0.7850.99
291_Y436_R0.7850.99
348_L353_A0.7850.99
557_P562_L0.7790.99
269_C274_D0.7790.99
94_N102_E0.7790.99
541_E544_V0.7790.99
395_S398_A0.7790.99
563_A568_Q0.7780.99
31_Q293_F0.7780.99
560_G565_D0.7760.99
106_L266_K0.7740.99
541_E550_E0.7740.99
180_G338_R0.7720.99
390_V503_A0.7720.99
40_R46_V0.7710.99
27_L371_I0.7700.99
522_G525_V0.7680.99
551_V572_T0.7670.99
334_M340_T0.7660.99
522_G536_D0.7640.99
529_K533_N0.7630.99
150_K172_I0.7630.99
48_F92_Y0.7620.99
11_T260_G0.7620.99
504_E511_L0.7610.99
542_A546_A0.7610.99
417_Q421_T0.7600.99
190_H231_D0.7590.99
423_T518_Q0.7590.99
552_K557_P0.7560.99
56_G60_M0.7540.99
201_M205_W0.7530.99
63_A70_P0.7520.99
102_E270_D0.7520.99
125_I231_D0.7510.99
454_R458_E0.7500.99
180_G337_S0.7490.99
462_W473_D0.7480.99
547_S576_F0.7480.99
431_E434_E0.7470.99
242_E248_G0.7460.99
465_A473_D0.7460.99
391_V499_L0.7460.99
362_A381_R0.7460.99
127_Q136_F0.7450.99
424_D427_E0.7450.99
396_R400_F0.7440.99
467_Q473_D0.7430.99
393_L456_V0.7420.99
421_T526_N0.7420.99
107_S256_D0.7410.99
535_I538_R0.7400.99
502_R505_A0.7400.99
145_T180_G0.7380.99
6_K39_Q0.7380.99
328_T372_D0.7370.99
423_T520_L0.7360.99
529_K532_Y0.7350.99
68_I76_E0.7340.99
110_I255_L0.7320.99
160_E163_G0.7310.99
562_L566_P0.7310.99
34_V495_V0.7290.99
393_L449_A0.7280.99
511_L514_D0.7270.99
373_L378_F0.7260.99
558_V564_D0.7250.99
5_A44_H0.7250.99
112_S115_K0.7250.99
498_K502_R0.7250.99
569_E573_F0.7240.99
110_I259_I0.7230.99
541_E545_E0.7210.99
569_E572_T0.7210.99
552_K558_V0.7190.99
202_L308_A0.7170.99
564_D572_T0.7170.99
375_L379_V0.7170.99
419_Y423_T0.7170.99
561_P568_Q0.7170.99
545_E550_E0.7170.99
282_W315_F0.7150.99
306_W318_P0.7150.99
346_T375_L0.7150.99
522_G528_F0.7140.99
12_C85_F0.7140.99
205_W316_R0.7130.99
426_A516_I0.7100.99
276_V280_E0.7090.99
397_N481_G0.7090.99
155_Y158_N0.7080.99
536_D541_E0.7070.99
118_G194_D0.7050.98
572_T576_F0.7020.98
136_F231_D0.7010.98
549_E552_K0.6980.98
41_M512_T0.6980.98
493_K504_E0.6980.98
31_Q361_T0.6980.98
493_K501_E0.6980.98
205_W209_G0.6970.98
425_A428_V0.6970.98
540_V543_L0.6970.98
565_D575_D0.6960.98
420_K423_T0.6930.98
445_I491_Y0.6920.98
8_I436_R0.6920.98
445_I488_L0.6910.98
538_R542_A0.6910.98
160_E168_P0.6900.98
75_G97_S0.6890.98
544_V549_E0.6880.98
206_T220_Q0.6880.98
533_N539_Q0.6870.98
398_A402_N0.6850.98
111_Y120_I0.6840.98
571_I576_F0.6840.98
475_Q478_C0.6820.98
142_V183_P0.6820.98
133_K180_G0.6800.98
420_K521_L0.6780.98
7_K285_D0.6770.98
32_A48_F0.6760.98
561_P572_T0.6760.98
423_T517_Q0.6760.98
9_L265_F0.6760.98
557_P564_D0.6760.98
566_P573_F0.6750.98
526_N530_A0.6750.98
528_F540_V0.6750.98
423_T516_I0.6750.98
7_K281_Y0.6750.98
105_Q109_L0.6720.98
415_D480_M0.6710.98
311_E316_R0.6710.98
253_V256_D0.6700.98
331_G372_D0.6690.98
571_I574_D0.6690.98
539_Q550_E0.6670.98
364_L371_I0.6670.98
145_T173_E0.6670.98
419_Y484_L0.6660.98
338_R341_F0.6650.98
464_V474_L0.6650.98
94_N100_S0.6640.98
296_K326_Y0.6630.98
564_D571_I0.6630.98
9_L285_D0.6620.98
544_V548_K0.6620.98
570_T574_D0.6610.98
557_P576_F0.6600.98
209_G316_R0.6590.98
304_L308_A0.6580.98
422_F480_M0.6580.98
432_A437_E0.6580.98
559_T564_D0.6570.98
440_K444_E0.6570.98
218_K221_E0.6560.98
429_I433_W0.6560.98
566_P569_E0.6550.98
384_A388_N0.6540.98
559_T569_E0.6520.97
526_N529_K0.6520.97
135_M179_S0.6510.97
415_D462_W0.6510.97
420_K526_N0.6510.97
561_P573_F0.6490.97
11_T284_K0.6490.97
543_L546_A0.6490.97
418_L480_M0.6480.97
115_K120_I0.6470.97
259_I309_M0.6470.97
47_N281_Y0.6470.97
377_D380_Q0.6460.97
202_L205_W0.6450.97
84_D343_K0.6430.97
68_I73_M0.6410.97
361_T495_V0.6410.97
329_V375_L0.6400.97
413_L528_F0.6400.97
123_R192_F0.6390.97
543_L548_K0.6390.97
198_F312_G0.6390.97
477_I480_M0.6390.97
464_V477_I0.6370.97
96_H260_G0.6360.97
390_V499_L0.6360.97
394_A398_A0.6360.97
502_R506_F0.6360.97
54_A97_S0.6350.97
533_N537_M0.6340.97
129_Y134_G0.6320.97
485_F507_L0.6320.97
41_M494_P0.6320.97
504_E508_N0.6320.97
58_P178_V0.6310.97
20_S343_K0.6280.97
414_A459_Q0.6270.97
516_I520_L0.6260.97
403_K478_C0.6260.97
465_A469_G0.6260.97
215_V218_K0.6240.97
328_T370_D0.6230.97
560_G566_P0.6230.97
562_L567_I0.6200.97
533_N540_V0.6190.97
535_I539_Q0.6160.96
329_V332_A0.6160.96
563_A566_P0.6150.96
168_P171_L0.6150.96
149_C152_P0.6140.96
412_E476_A0.6130.96
558_V566_P0.6120.96
195_L198_F0.6120.96
61_L65_Q0.6120.96
427_E521_L0.6120.96
527_P530_A0.6110.96
406_D409_L0.6100.96
361_T442_V0.6090.96
130_D137_L0.6090.96
211_L320_N0.6090.96
114_L117_N0.6070.96
393_L485_F0.6070.96
486_R508_N0.6070.96
484_L487_V0.6070.96
440_K443_R0.6060.96
153_D160_E0.6060.96
358_Y381_R0.6060.96
94_N267_N0.6050.96
27_L327_V0.6050.96
412_E462_W0.6050.96
424_D526_N0.6040.96
408_V411_S0.6030.96
486_R504_E0.6020.96
543_L547_S0.6010.96
568_Q573_F0.6000.96
29_H92_Y0.5990.96
211_L321_L0.5990.96
562_L568_Q0.5990.96
202_L307_P0.5990.96
28_E32_A0.5980.96
526_N538_R0.5980.96
390_V492_L0.5980.96
359_Y377_D0.5980.96
529_K543_L0.5970.96
523_H527_P0.5960.96
459_Q473_D0.5950.96
529_K544_V0.5940.96
148_K151_S0.5940.96
50_C94_N0.5920.96
390_V449_A0.5920.96
542_A545_E0.5920.96
37_R91_S0.5910.96
195_L227_L0.5900.95
262_M282_W0.5900.95
31_Q438_F0.5880.95
251_F255_L0.5870.95
524_K527_P0.5870.95
214_Q296_K0.5860.95
210_A216_A0.5860.95
213_E217_N0.5840.95
406_D410_A0.5830.95
525_V529_K0.5830.95
137_L183_P0.5800.95
322_F436_R0.5790.95
538_R541_E0.5780.95
563_A569_E0.5770.95
315_F319_S0.5770.95
513_W516_I0.5770.95
265_F282_W0.5760.95
504_E509_T0.5760.95
206_T223_F0.5750.95
307_P316_R0.5750.95
158_N164_A0.5750.95
6_K45_E0.5740.95
39_Q46_V0.5740.95
534_R538_R0.5740.95
196_P199_S0.5730.95
564_D570_T0.5730.95
84_D345_S0.5720.95
544_V550_E0.5720.95
539_Q542_A0.5720.95
416_P419_Y0.5710.95
64_Q70_P0.5710.95
145_T174_P0.5710.95
138_P141_F0.5700.95
389_K449_A0.5700.95
266_K277_S0.5690.95
128_L183_P0.5680.94
123_R229_Q0.5680.94
266_K270_D0.5680.94
280_E283_K0.5680.94
261_Y309_M0.5670.94
195_L308_A0.5670.94
198_F314_N0.5660.94
65_Q339_G0.5660.94
202_L304_L0.5660.94
550_E574_D0.5660.94
168_P173_E0.5660.94
104_R242_E0.5650.94
418_L455_Y0.5650.94
557_P563_A0.5650.94
530_A533_N0.5640.94
569_E575_D0.5640.94
19_G25_H0.5630.94
52_D78_S0.5630.94
311_E314_N0.5630.94
127_Q137_L0.5630.94
110_I114_L0.5630.94
137_L176_S0.5610.94
120_I193_F0.5590.94
422_F425_A0.5570.94
395_S506_F0.5570.94
559_T565_D0.5560.94
278_F282_W0.5560.94
347_W373_L0.5550.94
421_T448_L0.5550.94
560_G573_F0.5540.94
56_G70_P0.5540.94
557_P575_D0.5540.94
565_D569_E0.5530.94
9_L281_Y0.5530.94
377_D381_R0.5520.94
341_F344_A0.5500.93
172_I175_K0.5500.93
62_K73_M0.5490.93
466_K474_L0.5490.93
475_Q479_S0.5490.93
96_H264_S0.5480.93
426_A429_I0.5460.93
559_T566_P0.5460.93
156_G163_G0.5460.93
479_S483_N0.5450.93
565_D576_F0.5450.93
347_W375_L0.5450.93
75_G100_S0.5440.93
566_P570_T0.5440.93
526_N540_V0.5440.93
21_I81_H0.5440.93
499_L502_R0.5440.93
400_F478_C0.5440.93
563_A567_I0.5440.93
407_G410_A0.5440.93
62_K337_S0.5430.93
534_R537_M0.5430.93
568_Q576_F0.5430.93
300_Y304_L0.5420.93
558_V565_D0.5410.93
563_A570_T0.5400.93
156_G160_E0.5400.93
74_I78_S0.5390.93
414_A417_Q0.5390.93
546_A551_V0.5390.93
292_H306_W0.5380.93
562_L569_E0.5370.93
219_M321_L0.5360.93
528_F539_Q0.5350.93
517_Q521_L0.5340.92
113_R313_S0.5340.92
564_D576_F0.5330.92
179_S182_T0.5330.92
267_N270_D0.5320.92
417_Q451_L0.5320.92
190_H235_D0.5300.92
412_E459_Q0.5280.92
334_M339_G0.5280.92
106_L263_G0.5280.92
448_L491_Y0.5280.92
564_D573_F0.5270.92
496_L500_T0.5270.92
206_T209_G0.5270.92
192_F231_D0.5270.92
293_F324_H0.5260.92
417_Q420_K0.5260.92
484_L488_L0.5260.92
96_H100_S0.5260.92
415_D477_I0.5250.92
114_L193_F0.5250.92
71_E100_S0.5250.92
191_F246_A0.5240.92
209_G216_A0.5240.92
115_K245_N0.5230.92
89_N353_A0.5220.92
532_Y539_Q0.5220.92
120_I251_F0.5210.92
560_G567_I0.5210.92
28_E293_F0.5200.91
232_I243_I0.5190.91
407_G411_S0.5190.91
451_L454_R0.5180.91
376_E380_Q0.5170.91
459_Q462_W0.5170.91
536_D542_A0.5170.91
423_T487_V0.5160.91
159_C164_A0.5150.91
561_P567_I0.5140.91
558_V563_A0.5140.91
66_L73_M0.5130.91
513_W517_Q0.5120.91
262_M310_L0.5120.91
401_I478_C0.5120.91
295_G326_Y0.5110.91
5_A512_T0.5100.91
497_P500_T0.5070.90
546_A550_E0.5060.90
560_G569_E0.5060.90
505_A509_T0.5050.90
295_G324_H0.5050.90
558_V572_T0.5040.90
125_I188_S0.5040.90
215_V296_K0.5040.90
104_R108_E0.5040.90
148_K164_A0.5030.90
392_N396_R0.5030.90
394_A397_N0.5030.90
456_V481_G0.5020.90
21_I84_D0.5010.90
563_A572_T0.5010.90
570_T575_D0.5010.90
265_F277_S0.5000.90
536_D547_S0.5000.90
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1rqgA 2 0.8139 100 0.187 Contact Map
1gaxA 1 0.9306 100 0.282 Contact Map
1ffyA 1 0.9069 100 0.305 Contact Map
1ileA 1 0.7888 100 0.326 Contact Map
3h99A 1 0.8021 100 0.357 Contact Map
1wz2A 1 0.9247 100 0.36 Contact Map
3kflA 1 0.7459 100 0.369 Contact Map
3ziuA 1 0.7489 100 0.382 Contact Map
4qreA 1 0.74 100 0.388 Contact Map
4arcA 1 0.7386 100 0.394 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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