SYA - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

SYA - Alanine--tRNA ligase

UniProt:	P00957	Sequences: MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGMNQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDNKGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDLSNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKLVGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDGETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMIRVDSASEFKGYDHLELNGKVTALFVDGKAVDAINAGQEAVVVLDQTPFYAESGGQVGDKGELKGANFSFAVEDTQKYGQAIGHIGKLAAGSLKVGDAVQADVDEARRARIRLNHSATHLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNTQIRRNLPIETNIMDLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRIISESGTAAGVRRIEAVTGEGAIATVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTRQLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLGSTIIVLATVVEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTDAAALPAALASVKGWVSAKLQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10034
Length:	876 (854)
Sequences:	3998 (2372)
Seq/√Len:	81.2

ECOLI - SYA
BACSU - SYA
HALSA - SYA
SULSO - SYA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
483_I	489_A	5.772	1.00
114_L	121_F	4.891	1.00
464_L	552_V	4.386	1.00
468_G	494_D	4.137	1.00
519_F	535_G	4.087	1.00
14_D	17_H	4.009	1.00
105_H	146_E	3.989	1.00
10_Q	14_D	3.904	1.00
766_I	868_K	3.893	1.00
565_S	658_M	3.854	1.00
623_N	673_R	3.789	1.00
827_K	830_E	3.779	1.00
266_A	269_K	3.749	1.00
563_N	699_T	3.622	1.00
777_E	861_P	3.564	1.00
493_L	550_A	3.442	1.00
141_E	145_K	3.399	1.00
280_S	320_H	3.339	1.00
604_M	612_V	3.275	1.00
632_D	635_A	3.256	1.00
799_S	821_D	3.252	1.00
507_G	524_T	3.195	1.00
556_R	560_I	3.142	1.00
604_M	609_I	3.032	1.00
520_A	538_A	3.031	1.00
336_G	357_E	2.964	1.00
475_V	487_Q	2.939	1.00
430_E	434_R	2.885	1.00
421_D	424_G	2.876	1.00
805_A	860_L	2.869	1.00
410_A	422_E	2.866	1.00
457_E	495_Q	2.817	1.00
459_K	466_L	2.773	1.00
428_A	431_E	2.773	1.00
144_E	151_R	2.728	1.00
717_V	732_V	2.704	1.00
619_Q	622_R	2.675	1.00
859_A	862_A	2.642	1.00
395_A	406_V	2.634	1.00
222_Q	226_T	2.596	1.00
767_D	770_G	2.588	1.00
19_K	113_E	2.584	1.00
576_Q	615_L	2.583	1.00
395_A	420_V	2.565	1.00
739_T	742_L	2.558	1.00
422_E	426_E	2.530	1.00
467_N	547_A	2.520	1.00
10_Q	23_V	2.463	1.00
261_R	265_Q	2.463	1.00
488_E	536_K	2.457	1.00
11_A	114_L	2.435	1.00
790_V	817_G	2.394	1.00
767_D	772_K	2.388	1.00
469_K	547_A	2.383	1.00
294_L	299_V	2.352	1.00
343_G	350_K	2.345	1.00
222_Q	228_E	2.332	1.00
630_I	652_R	2.304	1.00
514_G	517_F	2.303	1.00
465_E	551_D	2.301	1.00
602_E	608_E	2.271	1.00
378_L	412_V	2.259	1.00
388_D	419_K	2.256	1.00
635_A	638_A	2.252	1.00
13_L	23_V	2.246	1.00
302_S	307_G	2.233	1.00
520_A	536_K	2.230	1.00
623_N	675_G	2.214	1.00
130_V	149_I	2.202	1.00
671_A	677_I	2.199	1.00
856_D	859_A	2.185	1.00
577_V	615_L	2.185	1.00
117_S	125_K	2.185	1.00
512_L	548_V	2.173	1.00
611_A	614_D	2.173	1.00
616_V	680_F	2.118	1.00
717_V	728_L	2.117	1.00
390_L	413_C	2.115	1.00
581_H	600_H	2.114	1.00
746_L	749_L	2.095	1.00
572_A	576_Q	2.085	1.00
117_S	120_W	2.065	1.00
137_D	156_R	2.062	1.00
782_E	785_M	2.060	1.00
328_E	333_K	2.048	1.00
389_T	419_K	2.035	1.00
221_R	227_M	2.033	1.00
332_Y	361_K	2.027	1.00
430_E	433_R	2.020	1.00
27_S	46_Q	2.019	1.00
469_K	494_D	2.012	1.00
113_E	117_S	2.002	1.00
509_K	556_R	1.996	1.00
633_L	637_K	1.987	1.00
431_E	435_R	1.983	1.00
17_H	23_V	1.973	1.00
88_H	254_N	1.962	1.00
518_S	539_A	1.931	1.00
605_K	608_E	1.923	1.00
513_K	551_D	1.919	1.00
866_S	869_G	1.914	1.00
737_E	741_Q	1.903	1.00
836_A	852_A	1.899	1.00
456_S	531_I	1.881	1.00
406_V	422_E	1.875	1.00
608_E	611_A	1.871	1.00
391_D	394_T	1.868	1.00
366_Q	369_R	1.864	1.00
211_I	247_V	1.846	1.00
137_D	141_E	1.839	1.00
838_Q	859_A	1.835	1.00
141_E	144_E	1.824	1.00
15_F	19_K	1.818	1.00
381_E	390_L	1.804	1.00
803_V	816_A	1.801	1.00
491_V	542_L	1.801	1.00
111_A	214_I	1.795	1.00
128_L	185_I	1.788	1.00
195_G	203_E	1.778	1.00
423_A	426_E	1.771	1.00
121_F	248_L	1.764	1.00
296_A	356_V	1.763	1.00
271_T	326_A	1.763	1.00
115_L	211_I	1.751	1.00
760_N	763_S	1.750	1.00
610_R	614_D	1.747	1.00
321_G	330_F	1.744	1.00
268_A	281_L	1.736	1.00
556_R	591_D	1.736	1.00
820_K	824_D	1.734	1.00
818_V	822_V	1.732	1.00
353_Q	357_E	1.728	1.00
861_P	865_A	1.727	1.00
194_W	202_E	1.723	1.00
381_E	394_T	1.716	1.00
339_I	353_Q	1.708	1.00
489_A	519_F	1.697	1.00
265_Q	268_A	1.697	1.00
42_A	45_N	1.696	1.00
629_N	639_K	1.687	1.00
764_K	776_S	1.687	1.00
106_D	109_Q	1.683	1.00
13_L	63_T	1.680	1.00
144_E	154_I	1.676	1.00
742_L	746_L	1.675	1.00
105_H	109_Q	1.671	1.00
482_A	543_K	1.669	1.00
562_L	621_R	1.666	1.00
491_V	512_L	1.661	1.00
803_V	867_V	1.655	1.00
15_F	110_F	1.653	1.00
790_V	815_I	1.650	1.00
140_Y	156_R	1.644	1.00
195_G	205_G	1.639	1.00
109_Q	146_E	1.632	1.00
473_L	491_V	1.629	1.00
18_S	120_W	1.629	1.00
467_N	549_Q	1.620	1.00
634_E	638_A	1.619	1.00
400_D	432_Q	1.612	1.00
838_Q	866_S	1.607	1.00
361_K	365_E	1.605	1.00
575_R	583_S	1.600	1.00
543_K	546_D	1.592	1.00
267_V	281_L	1.592	1.00
382_L	418_I	1.583	1.00
262_T	341_V	1.583	1.00
291_C	314_I	1.581	1.00
50_V	57_R	1.571	1.00
23_V	63_T	1.563	1.00
229_P	233_P	1.562	1.00
497_P	550_A	1.553	1.00
519_F	542_L	1.552	1.00
434_R	438_E	1.547	1.00
129_W	155_I	1.536	0.99
631_M	639_K	1.522	0.99
251_V	256_D	1.514	0.99
117_S	122_A	1.506	0.99
489_A	535_G	1.505	0.99
105_H	145_K	1.504	0.99
814_L	839_V	1.500	0.99
427_A	431_E	1.498	0.99
639_K	663_T	1.495	0.99
336_G	353_Q	1.492	0.99
266_A	337_P	1.486	0.99
464_L	554_E	1.484	0.99
468_G	495_Q	1.482	0.99
626_I	658_M	1.467	0.99
423_A	427_A	1.466	0.99
493_L	512_L	1.466	0.99
273_A	277_S	1.458	0.99
797_L	800_T	1.456	0.99
378_L	382_L	1.450	0.99
479_A	544_V	1.448	0.99
482_A	541_S	1.441	0.99
521_V	535_G	1.439	0.99
83_Y	414_R	1.438	0.99
490_V	532_G	1.436	0.99
745_E	750_K	1.434	0.99
542_L	548_V	1.433	0.99
614_D	618_T	1.430	0.99
132_V	156_R	1.429	0.99
61_R	101_D	1.427	0.99
488_E	522_E	1.424	0.99
17_H	22_Q	1.423	0.99
140_Y	144_E	1.419	0.99
502_S	526_K	1.418	0.99
522_E	535_G	1.416	0.99
575_R	642_M	1.412	0.99
672_S	676_D	1.404	0.99
195_G	200_S	1.398	0.99
11_A	120_W	1.397	0.99
518_S	538_A	1.396	0.99
657_S	663_T	1.394	0.99
314_I	360_L	1.393	0.99
114_L	248_L	1.390	0.99
513_K	518_S	1.384	0.99
140_Y	151_R	1.384	0.99
837_Q	842_K	1.381	0.99
468_G	550_A	1.380	0.99
627_E	657_S	1.375	0.99
393_E	428_A	1.373	0.99
701_E	705_A	1.368	0.99
134_E	158_G	1.365	0.99
106_D	110_F	1.364	0.99
610_R	712_D	1.364	0.99
8_I	245_A	1.356	0.99
569_L	616_V	1.355	0.99
720_L	733_R	1.355	0.99
493_L	548_V	1.350	0.99
19_K	110_F	1.349	0.99
209_I	246_A	1.344	0.99
832_I	852_A	1.343	0.99
738_R	743_E	1.343	0.99
807_V	810_G	1.339	0.99
142_I	147_V	1.338	0.99
124_P	127_R	1.338	0.99
15_F	113_E	1.336	0.99
632_D	652_R	1.335	0.99
512_L	550_A	1.334	0.99
292_A	335_V	1.333	0.99
14_D	23_V	1.328	0.98
506_V	560_I	1.328	0.98
11_A	121_F	1.323	0.98
689_A	692_V	1.323	0.98
519_F	537_L	1.322	0.98
124_P	187_Y	1.320	0.98
465_E	549_Q	1.318	0.98
65_S	346_G	1.318	0.98
197_P	200_S	1.317	0.98
727_N	730_D	1.314	0.98
517_F	542_L	1.314	0.98
777_E	807_V	1.312	0.98
865_A	868_K	1.311	0.98
801_I	826_V	1.310	0.98
838_Q	862_A	1.303	0.98
40_T	45_N	1.297	0.98
354_A	357_E	1.290	0.98
842_K	855_T	1.290	0.98
6_A	344_S	1.286	0.98
37_L	41_N	1.284	0.98
183_T	235_V	1.283	0.98
358_Q	602_E	1.282	0.98
129_W	153_R	1.282	0.98
14_D	18_S	1.282	0.98
522_E	536_K	1.275	0.98
350_K	353_Q	1.267	0.98
121_F	244_I	1.265	0.98
514_G	548_V	1.264	0.98
623_N	676_D	1.263	0.98
266_A	270_V	1.262	0.98
559_R	700_G	1.261	0.98
812_V	857_A	1.256	0.98
525_Q	534_I	1.256	0.98
386_S	416_R	1.255	0.98
600_H	608_E	1.253	0.98
571_H	642_M	1.252	0.98
830_E	833_G	1.250	0.98
620_I	680_F	1.248	0.98
590_N	593_V	1.247	0.98
773_L	871_V	1.246	0.98
628_T	656_L	1.246	0.98
679_L	707_V	1.238	0.98
834_M	866_S	1.236	0.98
840_G	856_D	1.232	0.97
615_L	661_F	1.231	0.97
470_V	491_V	1.231	0.97
702_G	705_A	1.229	0.97
105_H	142_I	1.223	0.97
560_I	591_D	1.222	0.97
865_A	869_G	1.222	0.97
183_T	214_I	1.219	0.97
139_A	183_T	1.214	0.97
765_A	774_L	1.214	0.97
459_K	495_Q	1.212	0.97
558_A	561_R	1.210	0.97
40_T	46_Q	1.209	0.97
839_V	859_A	1.209	0.97
625_P	673_R	1.208	0.97
142_I	146_E	1.207	0.97
826_V	871_V	1.207	0.97
127_R	187_Y	1.205	0.97
470_V	542_L	1.205	0.97
800_T	819_S	1.205	0.97
485_A	539_A	1.204	0.97
619_Q	624_L	1.204	0.97
484_N	487_Q	1.203	0.97
631_M	635_A	1.202	0.97
268_A	271_T	1.198	0.97
827_K	847_P	1.195	0.97
406_V	420_V	1.195	0.97
820_K	848_D	1.193	0.97
407_D	411_D	1.192	0.97
559_R	701_E	1.191	0.97
792_D	795_N	1.188	0.97
22_Q	59_Y	1.184	0.97
10_Q	17_H	1.183	0.97
132_V	140_Y	1.181	0.97
634_E	637_K	1.177	0.97
833_G	837_Q	1.173	0.97
424_G	428_A	1.173	0.97
200_S	205_G	1.172	0.97
594_L	697_A	1.171	0.97
429_M	432_Q	1.171	0.97
774_L	793_L	1.170	0.97
862_A	865_A	1.170	0.97
762_S	765_A	1.168	0.97
585_K	599_S	1.165	0.96
200_S	203_E	1.162	0.96
619_Q	661_F	1.161	0.96
818_V	828_A	1.158	0.96
799_S	819_S	1.155	0.96
512_L	521_V	1.150	0.96
833_G	842_K	1.149	0.96
682_I	695_I	1.148	0.96
511_E	518_S	1.147	0.96
681_R	711_S	1.147	0.96
463_H	552_V	1.141	0.96
123_L	247_V	1.140	0.96
607_E	611_A	1.140	0.96
24_V	64_T	1.139	0.96
799_S	822_V	1.133	0.96
517_F	548_V	1.130	0.96
28_S	32_H	1.128	0.96
41_N	173_M	1.126	0.96
862_A	866_S	1.123	0.96
790_V	802_I	1.122	0.96
64_T	97_F	1.122	0.96
483_I	519_F	1.121	0.96
115_L	128_L	1.120	0.96
220_N	228_E	1.120	0.96
822_V	826_V	1.119	0.96
500_A	531_I	1.118	0.96
56_K	60_S	1.116	0.96
614_D	708_H	1.115	0.95
431_E	434_R	1.110	0.95
491_V	535_G	1.100	0.95
22_Q	62_A	1.096	0.95
268_A	274_T	1.095	0.95
432_Q	435_R	1.094	0.95
288_I	334_L	1.090	0.95
24_V	62_A	1.088	0.95
146_E	149_I	1.086	0.95
7_E	11_A	1.082	0.95
217_M	234_S	1.077	0.95
470_V	548_V	1.077	0.95
239_M	244_I	1.073	0.94
658_M	674_T	1.072	0.94
264_I	268_A	1.072	0.94
314_I	318_V	1.070	0.94
389_T	421_D	1.070	0.94
257_I	262_T	1.067	0.94
736_L	739_T	1.059	0.94
335_V	339_I	1.059	0.94
778_L	781_V	1.057	0.94
33_N	55_D	1.053	0.94
807_V	860_L	1.051	0.94
65_S	94_L	1.051	0.94
788_T	792_D	1.050	0.94
391_D	395_A	1.050	0.94
10_Q	344_S	1.048	0.94
573_A	615_L	1.047	0.94
379_D	416_R	1.047	0.94
724_D	727_N	1.043	0.94
379_D	383_A	1.042	0.94
413_C	420_V	1.042	0.94
511_E	551_D	1.035	0.93
657_S	660_D	1.033	0.93
488_E	534_I	1.033	0.93
189_H	209_I	1.030	0.93
626_I	671_A	1.029	0.93
629_N	635_A	1.028	0.93
339_I	350_K	1.026	0.93
506_V	591_D	1.022	0.93
814_L	832_I	1.020	0.93
189_H	246_A	1.018	0.93
115_L	185_I	1.016	0.93
741_Q	745_E	1.016	0.93
744_K	747_Q	1.016	0.93
381_E	384_K	1.016	0.93
537_L	542_L	1.015	0.93
110_F	113_E	1.011	0.92
567_T	594_L	1.011	0.92
71_A	78_L	1.010	0.92
266_A	333_K	1.010	0.92
732_V	735_V	1.008	0.92
22_Q	58_N	1.007	0.92
783_P	813_S	1.007	0.92
434_R	437_R	1.007	0.92
816_A	835_V	1.006	0.92
765_A	772_K	1.005	0.92
189_H	252_N	1.003	0.92
292_A	338_L	1.003	0.92
685_E	693_R	1.002	0.92
576_Q	661_F	1.001	0.92
470_V	493_L	0.999	0.92
196_G	199_G	0.999	0.92
141_E	146_E	0.998	0.92
484_N	541_S	0.997	0.92
698_V	706_T	0.997	0.92
717_V	721_L	0.996	0.92
834_M	837_Q	0.995	0.92
442_F	445_D	0.993	0.92
78_L	313_I	0.993	0.92
61_R	110_F	0.993	0.92
172_Q	221_R	0.991	0.92
794_K	817_G	0.989	0.92
507_G	523_D	0.988	0.92
413_C	418_I	0.987	0.92
705_A	709_A	0.987	0.92
576_Q	611_A	0.986	0.92
604_M	608_E	0.986	0.92
188_D	207_R	0.984	0.91
4_S	7_E	0.983	0.91
611_A	615_L	0.982	0.91
426_E	430_E	0.980	0.91
745_E	748_Q	0.980	0.91
352_Q	355_Q	0.979	0.91
359_V	601_N	0.976	0.91
295_I	359_V	0.974	0.91
748_Q	751_E	0.974	0.91
509_K	560_I	0.971	0.91
572_A	642_M	0.968	0.91
728_L	732_V	0.967	0.91
483_I	487_Q	0.966	0.91
698_V	703_A	0.966	0.91
49_D	54_L	0.966	0.91
428_A	435_R	0.965	0.91
385_L	391_D	0.965	0.91
778_L	789_M	0.962	0.90
725_S	729_A	0.961	0.90
563_N	702_G	0.961	0.90
404_F	409_T	0.959	0.90
465_E	554_E	0.957	0.90
429_M	436_A	0.957	0.90
818_V	823_T	0.956	0.90
5_T	257_I	0.955	0.90
673_R	676_D	0.955	0.90
814_L	835_V	0.954	0.90
513_K	549_Q	0.952	0.90
490_V	534_I	0.950	0.90
777_E	864_L	0.949	0.90
805_A	864_L	0.949	0.90
271_T	281_L	0.948	0.90
498_F	550_A	0.948	0.90
468_G	548_V	0.944	0.90
129_W	208_Y	0.944	0.90
69_V	290_S	0.944	0.90
335_V	357_E	0.941	0.89
384_K	394_T	0.941	0.89
319_R	415_E	0.941	0.89
775_V	864_L	0.941	0.89
505_Q	669_T	0.940	0.89
509_K	522_E	0.937	0.89
618_T	622_R	0.936	0.89
867_V	871_V	0.936	0.89
137_D	140_Y	0.936	0.89
59_Y	62_A	0.936	0.89
29_L	294_L	0.934	0.89
709_A	712_D	0.930	0.89
109_Q	147_V	0.927	0.89
463_H	466_L	0.924	0.89
273_A	281_L	0.916	0.88
502_S	565_S	0.915	0.88
835_V	867_V	0.913	0.88
831_L	870_W	0.912	0.88
834_M	838_Q	0.910	0.88
322_N	372_E	0.909	0.88
629_N	657_S	0.907	0.88
27_S	40_T	0.905	0.88
42_A	68_C	0.905	0.88
8_I	121_F	0.905	0.88
773_L	868_K	0.903	0.87
555_A	701_E	0.899	0.87
733_R	737_E	0.899	0.87
464_L	561_R	0.894	0.87
15_F	117_S	0.894	0.87
19_K	120_W	0.892	0.87
784_K	842_K	0.892	0.87
737_E	740_R	0.889	0.87
452_V	479_A	0.889	0.87
123_L	127_R	0.888	0.87
109_Q	113_E	0.888	0.87
732_V	736_L	0.886	0.86
218_Q	229_P	0.886	0.86
814_L	852_A	0.882	0.86
13_L	17_H	0.882	0.86
614_D	705_A	0.881	0.86
553_D	556_R	0.879	0.86
710_D	714_L	0.878	0.86
570_M	594_L	0.878	0.86
182_C	186_F	0.877	0.86
491_V	519_F	0.877	0.86
263_L	338_L	0.876	0.86
730_D	733_R	0.875	0.86
706_T	710_D	0.875	0.86
839_V	854_G	0.874	0.86
466_L	495_Q	0.873	0.86
391_D	424_G	0.872	0.86
567_T	587_S	0.872	0.86
266_A	334_L	0.871	0.86
69_V	294_L	0.871	0.86
475_V	480_V	0.870	0.85
111_A	185_I	0.868	0.85
445_D	449_M	0.867	0.85
189_H	193_I	0.866	0.85
489_A	537_L	0.866	0.85
198_P	201_P	0.864	0.85
712_D	716_E	0.864	0.85
842_K	852_A	0.861	0.85
195_G	199_G	0.860	0.85
292_A	349_L	0.860	0.85
50_V	58_N	0.859	0.85
812_V	855_T	0.857	0.85
270_V	326_A	0.856	0.85
716_E	719_H	0.855	0.84
830_E	847_P	0.854	0.84
393_E	431_E	0.854	0.84
803_V	835_V	0.854	0.84
265_Q	269_K	0.853	0.84
249_Q	258_D	0.852	0.84
389_T	423_A	0.851	0.84
211_I	244_I	0.851	0.84
339_I	356_V	0.849	0.84
759_A	792_D	0.848	0.84
88_H	260_F	0.847	0.84
221_R	224_D	0.846	0.84
157_I	167_S	0.846	0.84
812_V	839_V	0.846	0.84
561_R	669_T	0.843	0.84
572_A	661_F	0.842	0.84
144_E	147_V	0.841	0.83
750_K	782_E	0.841	0.83
835_V	863_A	0.840	0.83
337_P	340_D	0.840	0.83
393_E	424_G	0.838	0.83
729_A	732_V	0.835	0.83
502_S	531_I	0.834	0.83
716_E	729_A	0.834	0.83
780_G	806_T	0.832	0.83
671_A	676_D	0.831	0.83
779_S	807_V	0.830	0.83
23_V	64_T	0.829	0.83
430_E	437_R	0.829	0.83
251_V	261_R	0.828	0.83
716_E	733_R	0.828	0.83
711_S	715_S	0.827	0.82
112_W	116_T	0.826	0.82
606_P	715_S	0.826	0.82
145_K	151_R	0.826	0.82
327_K	372_E	0.825	0.82
786_L	804_L	0.822	0.82
791_D	794_K	0.821	0.82
133_Y	167_S	0.819	0.82
624_L	659_G	0.818	0.82
288_I	338_L	0.816	0.82
818_V	826_V	0.815	0.82
839_V	852_A	0.815	0.82
71_A	313_I	0.815	0.82
354_A	358_Q	0.812	0.81
581_H	601_N	0.812	0.81
583_S	642_M	0.812	0.81
537_L	540_G	0.811	0.81
805_A	814_L	0.810	0.81
107_A	111_A	0.809	0.81
185_I	211_I	0.809	0.81
483_I	542_L	0.807	0.81
713_R	729_A	0.806	0.81
194_W	200_S	0.805	0.81
151_R	154_I	0.803	0.81
62_A	99_F	0.802	0.80
472_A	544_V	0.801	0.80
801_I	871_V	0.800	0.80
86_R	206_D	0.800	0.80
80_N	84_T	0.800	0.80
745_E	749_L	0.799	0.80
86_R	97_F	0.798	0.80
852_A	855_T	0.797	0.80
336_G	340_D	0.796	0.80
194_W	199_G	0.795	0.80
470_V	546_D	0.794	0.80
771_V	822_V	0.794	0.80
559_R	562_L	0.794	0.80
57_R	62_A	0.793	0.80
566_A	680_F	0.792	0.80
84_T	97_F	0.792	0.80
382_L	412_V	0.792	0.80
815_I	851_Q	0.790	0.79
108_I	214_I	0.789	0.79
186_F	202_E	0.787	0.79
455_A	529_Q	0.786	0.79
133_Y	158_G	0.786	0.79
473_L	544_V	0.784	0.79
241_L	259_L	0.784	0.79
110_F	217_M	0.784	0.79
140_Y	154_I	0.783	0.79
834_M	870_W	0.782	0.79
113_E	120_W	0.779	0.78
5_T	259_L	0.778	0.78
270_V	333_K	0.777	0.78
481_D	544_V	0.776	0.78
475_V	489_A	0.776	0.78
114_L	120_W	0.776	0.78
483_I	535_G	0.776	0.78
829_G	847_P	0.776	0.78
621_R	704_I	0.775	0.78
17_H	63_T	0.775	0.78
67_R	347_E	0.775	0.78
115_L	247_V	0.774	0.78
786_L	815_I	0.774	0.78
404_F	408_L	0.773	0.78
621_R	701_E	0.772	0.78
301_P	359_V	0.772	0.78
34_D	48_K	0.771	0.78
565_S	626_I	0.770	0.78
747_Q	751_E	0.769	0.78
110_F	234_S	0.768	0.78
67_R	348_D	0.767	0.77
720_L	736_L	0.765	0.77
576_Q	619_Q	0.764	0.77
88_H	255_Y	0.763	0.77
294_L	310_L	0.763	0.77
500_A	507_G	0.763	0.77
378_L	413_C	0.762	0.77
526_K	531_I	0.761	0.77
489_A	521_V	0.761	0.77
291_C	360_L	0.761	0.77
293_F	342_M	0.761	0.77
501_E	525_Q	0.761	0.77
470_V	517_F	0.760	0.77
457_E	460_G	0.760	0.77
283_V	320_H	0.759	0.77
134_E	137_D	0.759	0.77
388_D	418_I	0.758	0.77
150_P	154_I	0.757	0.76
388_D	417_N	0.756	0.76
444_A	449_M	0.756	0.76
196_G	200_S	0.756	0.76
812_V	854_G	0.755	0.76
679_L	704_I	0.755	0.76
60_S	232_K	0.754	0.76
190_G	208_Y	0.754	0.76
410_A	414_R	0.754	0.76
424_G	427_A	0.754	0.76
757_E	760_N	0.752	0.76
76_N	254_N	0.752	0.76
633_L	650_D	0.752	0.76
592_K	702_G	0.751	0.76
714_L	717_V	0.751	0.76
515_A	546_D	0.751	0.76
209_I	252_N	0.749	0.76
24_V	59_Y	0.749	0.76
798_G	821_D	0.749	0.76
866_S	870_W	0.748	0.76
480_V	483_I	0.748	0.76
322_N	327_K	0.748	0.76
291_C	331_F	0.747	0.76
108_I	139_A	0.746	0.75
197_P	201_P	0.746	0.75
79_E	83_Y	0.746	0.75
615_L	618_T	0.745	0.75
577_V	608_E	0.745	0.75
801_I	818_V	0.745	0.75
558_A	676_D	0.744	0.75
214_I	235_V	0.743	0.75
726_N	729_A	0.743	0.75
246_A	254_N	0.742	0.75
471_T	475_V	0.742	0.75
768_V	773_L	0.742	0.75
14_D	63_T	0.741	0.75
344_S	350_K	0.740	0.75
523_D	534_I	0.737	0.75
516_N	546_D	0.736	0.74
615_L	619_Q	0.736	0.74
836_A	839_V	0.736	0.74
385_L	418_I	0.735	0.74
107_A	214_I	0.735	0.74
751_E	788_T	0.734	0.74
721_L	732_V	0.734	0.74
725_S	728_L	0.733	0.74
392_G	428_A	0.733	0.74
29_L	69_V	0.731	0.74
791_D	846_R	0.731	0.74
39_F	173_M	0.730	0.74
108_I	147_V	0.730	0.74
642_M	665_L	0.730	0.74
12_F	239_M	0.730	0.74
470_V	512_L	0.729	0.74
196_G	203_E	0.728	0.74
681_R	706_T	0.728	0.74
5_T	245_A	0.727	0.74
639_K	657_S	0.726	0.73
506_V	590_N	0.726	0.73
158_G	167_S	0.726	0.73
609_I	682_I	0.726	0.73
578_L	604_M	0.725	0.73
399_Y	425_F	0.724	0.73
380_E	384_K	0.723	0.73
46_Q	64_T	0.722	0.73
340_D	343_G	0.721	0.73
486_G	537_L	0.721	0.73
801_I	822_V	0.721	0.73
192_H	250_H	0.721	0.73
748_Q	752_Q	0.721	0.73
464_L	669_T	0.720	0.73
589_V	594_L	0.719	0.73
471_T	494_D	0.719	0.73
52_L	220_N	0.718	0.73
45_N	52_L	0.717	0.73
328_E	332_Y	0.716	0.72
179_C	221_R	0.716	0.72
681_R	707_V	0.716	0.72
115_L	244_I	0.715	0.72
385_L	388_D	0.714	0.72
397_R	400_D	0.714	0.72
150_P	153_R	0.714	0.72
775_V	871_V	0.714	0.72
816_A	832_I	0.713	0.72
295_I	301_P	0.712	0.72
644_L	665_L	0.712	0.72
638_A	665_L	0.712	0.72
791_D	849_M	0.711	0.72
202_E	205_G	0.710	0.72
195_G	198_P	0.710	0.72
426_E	429_M	0.709	0.72
37_L	45_N	0.708	0.72
613_E	681_R	0.706	0.71
577_V	611_A	0.706	0.71
12_F	15_F	0.706	0.71
459_K	468_G	0.705	0.71
271_T	324_L	0.704	0.71
764_K	774_L	0.704	0.71
157_I	205_G	0.703	0.71
395_A	413_C	0.701	0.71
406_V	410_A	0.701	0.71
777_E	860_L	0.701	0.71
469_K	545_G	0.699	0.71
132_V	154_I	0.699	0.71
400_D	429_M	0.699	0.71
322_N	368_A	0.698	0.71
610_R	708_H	0.698	0.71
41_N	48_K	0.698	0.71
810_G	858_A	0.698	0.71
47_F	62_A	0.697	0.70
193_I	252_N	0.697	0.70
67_R	296_A	0.697	0.70
561_R	628_T	0.696	0.70
476_D	488_E	0.696	0.70
442_F	449_M	0.696	0.70
520_A	553_D	0.696	0.70
157_I	202_E	0.695	0.70
368_A	371_L	0.695	0.70
842_K	854_G	0.695	0.70
128_L	211_I	0.695	0.70
475_V	478_K	0.695	0.70
222_Q	227_M	0.695	0.70
63_T	97_F	0.694	0.70
174_G	234_S	0.693	0.70
267_V	285_A	0.693	0.70
805_A	812_V	0.693	0.70
52_L	227_M	0.692	0.70
436_A	439_A	0.692	0.70
406_V	429_M	0.692	0.70
199_G	202_E	0.691	0.70
18_S	113_E	0.689	0.70
474_F	479_A	0.688	0.69
61_R	106_D	0.686	0.69
442_F	446_Y	0.686	0.69
294_L	356_V	0.686	0.69
195_G	201_P	0.685	0.69
558_A	562_L	0.684	0.69
399_Y	429_M	0.684	0.69
471_T	492_V	0.683	0.69
473_L	483_I	0.683	0.69
80_N	97_F	0.683	0.69
858_A	861_P	0.683	0.69
512_L	519_F	0.683	0.69
473_L	489_A	0.682	0.69
78_L	173_M	0.681	0.69
44_M	68_C	0.681	0.69
507_G	525_Q	0.681	0.69
376_A	380_E	0.681	0.69
217_M	233_P	0.678	0.68
190_G	207_R	0.678	0.68
572_A	615_L	0.677	0.68
83_Y	279_K	0.677	0.68
88_H	259_L	0.677	0.68
196_G	204_D	0.674	0.68
554_E	558_A	0.674	0.68
189_H	250_H	0.674	0.68
193_I	208_Y	0.672	0.68
512_L	517_F	0.672	0.68
517_F	540_G	0.672	0.68
47_F	99_F	0.671	0.67
292_A	339_I	0.671	0.67
427_A	430_E	0.671	0.67
565_S	671_A	0.670	0.67
502_S	561_R	0.670	0.67
25_A	28_S	0.670	0.67
201_P	205_G	0.670	0.67
194_W	201_P	0.670	0.67
473_L	479_A	0.669	0.67
746_L	750_K	0.669	0.67
50_V	55_D	0.669	0.67
123_L	187_Y	0.668	0.67
496_T	533_H	0.667	0.67
762_S	793_L	0.667	0.67
456_S	459_K	0.667	0.67
245_A	251_V	0.666	0.67
500_A	524_T	0.665	0.67
805_A	863_A	0.665	0.67
378_L	390_L	0.664	0.67
759_A	796_Q	0.664	0.67
772_K	798_G	0.664	0.67
793_L	804_L	0.664	0.67
19_K	109_Q	0.663	0.67
569_L	680_F	0.663	0.67
446_Y	449_M	0.662	0.66
186_F	208_Y	0.662	0.66
374_G	404_F	0.661	0.66
511_E	520_A	0.661	0.66
454_S	530_A	0.661	0.66
756_Q	759_A	0.660	0.66
830_E	837_Q	0.660	0.66
522_E	534_I	0.659	0.66
172_Q	227_M	0.658	0.66
517_F	539_A	0.658	0.66
128_L	247_V	0.657	0.66
256_D	264_I	0.657	0.66
577_V	612_V	0.656	0.66
46_Q	62_A	0.654	0.66
483_I	537_L	0.654	0.66
683_I	698_V	0.654	0.66
32_H	45_N	0.653	0.65
731_K	734_S	0.653	0.65
40_T	69_V	0.653	0.65
631_M	655_V	0.652	0.65
40_T	47_F	0.652	0.65
257_I	260_F	0.652	0.65
263_L	337_P	0.651	0.65
784_K	788_T	0.651	0.65
854_G	857_A	0.651	0.65
459_K	463_H	0.650	0.65
296_A	348_D	0.649	0.65
409_T	420_V	0.648	0.65
139_A	156_R	0.647	0.65
135_S	158_G	0.647	0.65
569_L	619_Q	0.647	0.65
835_V	838_Q	0.647	0.65
339_I	349_L	0.647	0.65
762_S	800_T	0.646	0.65
771_V	825_R	0.645	0.64
836_A	854_G	0.644	0.64
794_K	819_S	0.644	0.64
630_I	663_T	0.644	0.64
78_L	175_D	0.643	0.64
11_A	248_L	0.642	0.64
221_R	225_G	0.641	0.64
491_V	521_V	0.640	0.64
618_T	701_E	0.639	0.64
395_A	409_T	0.639	0.64
587_S	594_L	0.639	0.64
775_V	867_V	0.638	0.64
578_L	581_H	0.638	0.64
458_F	557_R	0.638	0.64
444_A	447_N	0.637	0.63
713_R	728_L	0.637	0.63
462_D	552_V	0.636	0.63
566_A	594_L	0.636	0.63
815_I	849_M	0.635	0.63
132_V	144_E	0.635	0.63
569_L	573_A	0.635	0.63
71_A	173_M	0.635	0.63
245_A	249_Q	0.635	0.63
187_Y	211_I	0.634	0.63
565_S	659_G	0.633	0.63
33_N	49_D	0.633	0.63
448_A	452_V	0.632	0.63
222_Q	225_G	0.632	0.63
468_G	493_L	0.632	0.63
502_S	628_T	0.631	0.63
506_V	588_L	0.631	0.63
572_A	619_Q	0.631	0.63
708_H	711_S	0.629	0.63
268_A	273_A	0.629	0.63
50_V	59_Y	0.628	0.62
517_F	546_D	0.627	0.62
723_G	727_N	0.627	0.62
176_T	223_A	0.626	0.62
716_E	720_L	0.626	0.62
71_A	234_S	0.626	0.62
207_R	252_N	0.625	0.62
246_A	252_N	0.625	0.62
633_L	665_L	0.622	0.62
569_L	674_T	0.622	0.62
276_L	279_K	0.621	0.62
126_E	153_R	0.620	0.61
464_L	556_R	0.620	0.61
642_M	663_T	0.620	0.61
133_Y	182_C	0.620	0.61
798_G	819_S	0.618	0.61
40_T	227_M	0.618	0.61
629_N	632_D	0.617	0.61
199_G	208_Y	0.617	0.61
76_N	80_N	0.616	0.61
155_I	167_S	0.616	0.61
729_A	733_R	0.615	0.61
78_L	234_S	0.615	0.61
453_D	456_S	0.614	0.61
80_N	83_Y	0.613	0.61
573_A	577_V	0.613	0.61
115_L	147_V	0.612	0.60
283_V	288_I	0.612	0.60
710_D	713_R	0.611	0.60
262_T	265_Q	0.611	0.60
622_R	625_P	0.611	0.60
822_V	825_R	0.610	0.60
493_L	519_F	0.609	0.60
140_Y	145_K	0.608	0.60
27_S	64_T	0.607	0.60
795_N	820_K	0.607	0.60
704_I	708_H	0.606	0.60
852_A	857_A	0.606	0.60
81_V	283_V	0.606	0.60
132_V	139_A	0.606	0.60
144_E	150_P	0.605	0.60
739_T	743_E	0.604	0.59
738_R	741_Q	0.604	0.59
593_V	696_E	0.604	0.59
816_A	839_V	0.604	0.59
129_W	152_E	0.604	0.59
41_N	170_F	0.604	0.59
773_L	867_V	0.603	0.59
108_I	142_I	0.602	0.59
247_V	259_L	0.601	0.59
575_R	580_T	0.601	0.59
12_F	42_A	0.600	0.59
572_A	624_L	0.600	0.59
578_L	582_V	0.599	0.59
571_H	582_V	0.599	0.59
49_D	55_D	0.598	0.59
514_G	546_D	0.598	0.59
179_C	225_G	0.598	0.59
105_H	141_E	0.597	0.59
293_F	348_D	0.597	0.59
131_T	201_P	0.597	0.59
292_A	356_V	0.597	0.59
828_A	850_A	0.597	0.59
179_C	227_M	0.597	0.59
772_K	799_S	0.597	0.59
107_A	110_F	0.595	0.58
46_Q	68_C	0.595	0.58
191_D	208_Y	0.595	0.58
577_V	604_M	0.594	0.58
224_D	228_E	0.594	0.58
300_M	355_Q	0.594	0.58
390_L	424_G	0.593	0.58
854_G	863_A	0.593	0.58
71_A	175_D	0.593	0.58
377_L	381_E	0.593	0.58
644_L	647_E	0.592	0.58
569_L	588_L	0.592	0.58
475_V	483_I	0.592	0.58
344_S	347_E	0.591	0.58
94_L	239_M	0.591	0.58
640_G	643_A	0.591	0.58
5_T	260_F	0.590	0.58
435_R	439_A	0.590	0.58
109_Q	142_I	0.590	0.58
390_L	418_I	0.589	0.57
172_Q	217_M	0.589	0.57
566_A	677_I	0.589	0.57
189_H	247_V	0.589	0.57
329_T	332_Y	0.589	0.57
579_G	600_H	0.588	0.57
80_N	85_A	0.588	0.57
5_T	241_L	0.588	0.57
223_A	226_T	0.588	0.57
516_N	539_A	0.587	0.57
76_N	88_H	0.586	0.57
45_N	59_Y	0.586	0.57
619_Q	659_G	0.585	0.57
339_I	357_E	0.585	0.57
42_A	217_M	0.585	0.57
80_N	86_R	0.584	0.57
842_K	857_A	0.584	0.57
785_M	789_M	0.584	0.57
280_S	323_M	0.582	0.57
394_T	397_R	0.582	0.57
821_D	824_D	0.581	0.56
197_P	203_E	0.581	0.56
459_K	497_P	0.580	0.56
131_T	183_T	0.579	0.56
138_E	187_Y	0.579	0.56
781_V	806_T	0.579	0.56
624_L	674_T	0.579	0.56
628_T	669_T	0.578	0.56
31_P	40_T	0.578	0.56
840_G	859_A	0.578	0.56
738_R	742_L	0.577	0.56
56_K	232_K	0.576	0.56
256_D	261_R	0.576	0.56
173_M	313_I	0.576	0.56
578_L	608_E	0.575	0.56
28_S	40_T	0.575	0.56
157_I	201_P	0.574	0.56
45_N	220_N	0.574	0.56
263_L	341_V	0.574	0.56
426_E	433_R	0.574	0.56
201_P	204_D	0.574	0.56
762_S	774_L	0.573	0.55
559_R	702_G	0.572	0.55
105_H	110_F	0.572	0.55
346_G	356_V	0.572	0.55
90_F	310_L	0.572	0.55
170_F	179_C	0.572	0.55
134_E	156_R	0.571	0.55
829_G	833_G	0.571	0.55
582_V	599_S	0.571	0.55
797_L	819_S	0.571	0.55
811_K	853_G	0.571	0.55
8_I	114_L	0.571	0.55
393_E	397_R	0.570	0.55
47_F	173_M	0.569	0.55
199_G	203_E	0.569	0.55
606_P	610_R	0.569	0.55
377_L	397_R	0.569	0.55
186_F	201_P	0.568	0.55
771_V	775_V	0.568	0.55
535_G	540_G	0.568	0.55
437_R	440_S	0.568	0.55
168_D	186_F	0.568	0.55
24_V	27_S	0.568	0.55
221_R	226_T	0.568	0.55
309_V	313_I	0.568	0.55
843_G	850_A	0.568	0.55
45_N	62_A	0.567	0.55
264_I	285_A	0.567	0.55
125_K	150_P	0.567	0.55
821_D	825_R	0.567	0.55
42_A	46_Q	0.566	0.55
551_D	554_E	0.566	0.55
41_N	407_D	0.566	0.55
570_M	680_F	0.565	0.54
774_L	797_L	0.565	0.54
175_D	234_S	0.564	0.54
125_K	187_Y	0.564	0.54
830_E	834_M	0.564	0.54
219_F	229_P	0.564	0.54
846_R	851_Q	0.564	0.54
37_L	48_K	0.564	0.54
254_N	260_F	0.564	0.54
410_A	420_V	0.564	0.54
190_G	206_D	0.563	0.54
138_E	142_I	0.563	0.54
575_R	663_T	0.563	0.54
158_G	168_D	0.562	0.54
133_Y	181_P	0.562	0.54
139_A	235_V	0.562	0.54
173_M	227_M	0.562	0.54
335_V	360_L	0.562	0.54
34_D	37_L	0.562	0.54
443_G	449_M	0.561	0.54
39_F	294_L	0.561	0.54
50_V	62_A	0.561	0.54
768_V	771_V	0.560	0.54
449_M	452_V	0.560	0.54
137_D	151_R	0.560	0.54
714_L	728_L	0.560	0.54
260_F	285_A	0.559	0.54
131_T	155_I	0.559	0.54
789_M	792_D	0.559	0.54
835_V	870_W	0.559	0.54
209_I	248_L	0.559	0.54
97_F	235_V	0.558	0.53
513_K	517_F	0.558	0.53
288_I	331_F	0.558	0.53
42_A	278_N	0.558	0.53
824_D	847_P	0.557	0.53
194_W	203_E	0.557	0.53
635_A	639_K	0.556	0.53
643_A	647_E	0.556	0.53
795_N	798_G	0.556	0.53
382_L	390_L	0.555	0.53
116_T	128_L	0.555	0.53
9_R	92_E	0.555	0.53
31_P	41_N	0.554	0.53
832_I	851_Q	0.554	0.53
842_K	853_G	0.554	0.53
181_P	218_Q	0.554	0.53
612_V	695_I	0.554	0.53
145_K	148_G	0.553	0.53
603_A	687_G	0.553	0.53
280_S	283_V	0.553	0.53
202_E	206_D	0.552	0.53
400_D	435_R	0.552	0.53
191_D	194_W	0.552	0.53
137_D	142_I	0.552	0.53
199_G	209_I	0.549	0.52
617_N	679_L	0.549	0.52
262_T	337_P	0.549	0.52
193_I	250_H	0.548	0.52
259_L	262_T	0.547	0.52
134_E	167_S	0.547	0.52
761_L	776_S	0.547	0.52
374_G	409_T	0.547	0.52
85_A	206_D	0.546	0.52
720_L	732_V	0.545	0.52
194_W	209_I	0.544	0.52
328_E	361_K	0.544	0.52
115_L	121_F	0.544	0.52
202_E	208_Y	0.544	0.52
698_V	702_G	0.544	0.52
27_S	47_F	0.544	0.52
483_I	521_V	0.543	0.52
500_A	526_K	0.543	0.52
338_L	360_L	0.543	0.52
380_E	383_A	0.543	0.52
332_Y	357_E	0.542	0.51
340_D	353_Q	0.542	0.51
831_L	867_V	0.542	0.51
390_L	406_V	0.541	0.51
129_W	157_I	0.541	0.51
173_M	407_D	0.540	0.51
721_L	735_V	0.540	0.51
443_G	446_Y	0.540	0.51
608_E	612_V	0.539	0.51
803_V	870_W	0.539	0.51
48_K	173_M	0.539	0.51
750_K	785_M	0.539	0.51
196_G	201_P	0.538	0.51
476_D	487_Q	0.538	0.51
393_E	427_A	0.537	0.51
131_T	147_V	0.537	0.51
155_I	203_E	0.537	0.51
709_A	726_N	0.537	0.51
407_D	692_V	0.537	0.51
448_A	451_R	0.536	0.51
147_V	151_R	0.536	0.51
201_P	208_Y	0.536	0.51
312_R	404_F	0.536	0.51
321_G	325_G	0.536	0.51
5_T	246_A	0.536	0.51
744_K	748_Q	0.536	0.51
42_A	65_S	0.535	0.50
199_G	205_G	0.534	0.50
11_A	18_S	0.534	0.50
447_N	451_R	0.533	0.50
45_N	173_M	0.533	0.50
318_V	372_E	0.533	0.50
456_S	460_G	0.533	0.50
195_G	202_E	0.532	0.50
197_P	205_G	0.532	0.50
455_A	460_G	0.532	0.50
112_W	130_V	0.531	0.50
257_I	261_R	0.531	0.50
552_V	561_R	0.530	0.50
735_V	739_T	0.530	0.50
743_E	747_Q	0.530	0.50
189_H	206_D	0.530	0.50
832_I	839_V	0.529	0.50
511_E	538_A	0.529	0.50
406_V	426_E	0.529	0.50
381_E	391_D	0.529	0.50
566_A	697_A	0.529	0.50
293_F	346_G	0.528	0.50
603_A	606_P	0.528	0.50
12_F	36_T	0.528	0.50
709_A	713_R	0.527	0.49
69_V	310_L	0.527	0.49
575_R	582_V	0.527	0.49
79_E	279_K	0.527	0.49
509_K	524_T	0.527	0.49
192_H	252_N	0.527	0.49
816_A	867_V	0.527	0.49
40_T	173_M	0.525	0.49
746_L	753_A	0.525	0.49
807_V	812_V	0.525	0.49
578_L	600_H	0.525	0.49
47_F	59_Y	0.524	0.49
761_L	793_L	0.523	0.49
203_E	206_D	0.523	0.49
354_A	580_T	0.523	0.49
770_G	825_R	0.523	0.49
679_L	703_A	0.522	0.49
492_V	532_G	0.522	0.49
190_G	193_I	0.522	0.49
425_F	429_M	0.521	0.49
85_A	253_S	0.521	0.49
559_R	563_N	0.521	0.49
41_N	45_N	0.521	0.49
121_F	211_I	0.521	0.49
598_F	604_M	0.521	0.49
513_K	552_V	0.520	0.49
819_S	822_V	0.519	0.48
130_V	154_I	0.519	0.48
452_V	530_A	0.519	0.48
758_S	762_S	0.518	0.48
358_Q	601_N	0.518	0.48
686_S	696_E	0.518	0.48
713_R	717_V	0.518	0.48
412_V	415_E	0.518	0.48
628_T	654_R	0.516	0.48
593_V	683_I	0.516	0.48
704_I	707_V	0.516	0.48
217_M	221_R	0.516	0.48
572_A	575_R	0.515	0.48
432_Q	439_A	0.515	0.48
867_V	870_W	0.515	0.48
251_V	265_Q	0.515	0.48
52_L	173_M	0.515	0.48
517_F	541_S	0.515	0.48
123_L	248_L	0.515	0.48
736_L	740_R	0.514	0.48
189_H	235_V	0.514	0.48
202_E	209_I	0.514	0.48
713_R	716_E	0.513	0.48
490_V	535_G	0.513	0.48
681_R	698_V	0.513	0.48
157_I	203_E	0.513	0.48
19_K	117_S	0.512	0.47
275_D	278_N	0.512	0.47
176_T	221_R	0.512	0.47
512_L	547_A	0.511	0.47
125_K	131_T	0.511	0.47
457_E	630_I	0.511	0.47
561_R	672_S	0.510	0.47
65_S	345_A	0.510	0.47
131_T	186_F	0.510	0.47
194_W	197_P	0.509	0.47
45_N	227_M	0.509	0.47
464_L	560_I	0.509	0.47
97_F	110_F	0.508	0.47
30_V	299_V	0.508	0.47
555_A	618_T	0.507	0.47
48_K	175_D	0.507	0.47
135_S	156_R	0.507	0.47
47_F	64_T	0.507	0.47
765_A	797_L	0.507	0.47
157_I	186_F	0.506	0.47
529_Q	650_D	0.506	0.47
140_Y	167_S	0.505	0.47
11_A	122_A	0.505	0.47
855_T	859_A	0.504	0.46
770_G	799_S	0.504	0.46
20_G	59_Y	0.504	0.46
179_C	224_D	0.503	0.46
33_N	437_R	0.503	0.46
445_D	452_V	0.502	0.46
330_F	368_A	0.502	0.46
47_F	189_H	0.502	0.46
45_N	67_R	0.501	0.46
173_M	176_T	0.501	0.46
571_H	644_L	0.501	0.46
39_F	227_M	0.501	0.46
521_V	531_I	0.501	0.46
803_V	814_L	0.501	0.46
560_I	590_N	0.500	0.46
637_K	643_A	0.500	0.46
274_T	277_S	0.500	0.46
621_R	703_A	0.500	0.46

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3wqyA	2	0.8847	100	0.257	Contact Map
2zzeA	1	0.6644	100	0.351	Contact Map
2ztgA	1	0.6986	100	0.357	Contact Map
3hy0A	1	0.5034	100	0.427	Contact Map
1yfsA	1	0.5034	100	0.43	Contact Map
3kewA	1	0.258	100	0.825	Contact Map
2e1bA	1	0.2409	100	0.836	Contact Map
1nyrA	2	0.4121	100	0.908	Contact Map
4ce4c	1	0.2603	100	0.91	Contact Map
1tkeA	1	0.2363	100	0.91	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0197 seconds.