SYI - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

SYI - Isoleucine--tRNA ligase

UniProt:	P00956	Sequences: MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVDQDALKAKFAVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKDLVESVMQRIGVTDYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAWWDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMVVLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKADSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGLADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPELSAKLTALGDELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKVAEHAEICGRCVSNVAGDGEKRKFA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10492
Length:	938 (861)
Sequences:	4888 (2829)
Seq/√Len:	96.4

ECOLI - SYI SYV
BACSU - SYI SYV SYL
HALSA - SYI SYV SYL
SULSO - SYI SYV SYL2 SYL1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
36_D	39_G	5.664	1.00
265_Q	291_T	5.587	1.00
260_D	297_K	5.234	1.00
30_A	34_D	5.058	1.00
275_K	295_T	4.937	1.00
82_K	87_Y	4.660	1.00
33_T	142_I	4.094	1.00
262_A	275_K	3.855	1.00
374_V	382_I	3.807	1.00
439_K	449_Q	3.791	1.00
135_D	138_R	3.759	1.00
371_L	386_L	3.729	1.00
171_K	174_G	3.612	1.00
40_I	784_K	3.568	1.00
346_G	351_L	3.378	1.00
260_D	275_K	3.370	1.00
85_S	700_L	3.345	1.00
237_L	317_A	3.210	1.00
302_E	319_L	3.122	1.00
213_A	269_Q	3.083	1.00
259_F	325_L	3.071	1.00
601_R	607_I	2.929	1.00
260_D	295_T	2.924	1.00
757_E	761_R	2.865	1.00
125_K	128_E	2.822	1.00
105_K	108_Q	2.807	1.00
188_C	409_H	2.794	1.00
517_L	520_E	2.791	1.00
253_I	331_A	2.790	1.00
686_R	800_D	2.756	1.00
557_D	587_R	2.750	1.00
43_A	46_K	2.720	1.00
619_K	642_D	2.707	1.00
45_K	48_K	2.646	1.00
442_Q	588_Q	2.631	1.00
322_H	345_I	2.626	1.00
598_G	643_E	2.612	1.00
31_R	35_D	2.584	1.00
763_M	771_A	2.571	1.00
698_D	714_R	2.539	1.00
370_T	386_L	2.527	1.00
277_L	280_S	2.501	1.00
31_R	776_G	2.497	1.00
262_A	278_V	2.496	1.00
677_K	680_E	2.468	1.00
437_E	440_G	2.464	1.00
659_A	774_V	2.450	1.00
118_T	121_E	2.443	1.00
302_E	349_Y	2.415	1.00
432_A	436_K	2.414	1.00
322_H	334_T	2.392	1.00
80_K	768_S	2.384	1.00
318_I	345_I	2.316	1.00
29_L	769_F	2.306	1.00
839_A	869_T	2.282	1.00
270_A	293_L	2.280	1.00
433_Q	582_G	2.278	1.00
138_R	151_S	2.259	1.00
206_T	400_Q	2.258	1.00
138_R	142_I	2.253	1.00
134_V	155_L	2.244	1.00
237_L	331_A	2.242	1.00
386_L	390_K	2.202	1.00
51_F	706_Y	2.198	1.00
20_D	23_K	2.195	1.00
149_D	152_H	2.189	1.00
167_R	501_E	2.166	1.00
188_C	191_C	2.163	1.00
385_A	389_E	2.158	1.00
204_D	402_S	2.152	1.00
276_D	325_L	2.152	1.00
124_A	128_E	2.149	1.00
701_K	705_A	2.123	1.00
424_S	427_Q	2.118	1.00
343_Y	347_Q	2.108	1.00
49_K	87_Y	2.095	1.00
42_R	88_D	2.082	1.00
688_A	755_I	2.077	1.00
480_K	525_V	2.066	1.00
700_L	791_W	2.065	1.00
265_Q	270_A	2.062	1.00
253_I	306_F	2.056	1.00
281_V	285_I	2.054	1.00
558_M	590_L	2.044	1.00
204_D	400_Q	2.039	1.00
40_I	43_A	2.035	1.00
615_D	619_K	2.018	1.00
375_N	378_K	2.016	1.00
63_S	136_G	1.996	1.00
174_G	490_L	1.986	1.00
358_G	362_T	1.981	1.00
341_D	344_V	1.974	1.00
320_G	345_I	1.970	1.00
436_K	439_K	1.961	1.00
167_R	497_A	1.958	1.00
47_G	88_D	1.958	1.00
479_H	520_E	1.951	1.00
77_I	630_A	1.946	1.00
215_Q	392_A	1.937	1.00
81_S	704_E	1.933	1.00
382_I	385_A	1.932	1.00
558_M	588_Q	1.932	1.00
263_L	294_G	1.929	1.00
191_C	409_H	1.915	1.00
846_P	850_A	1.913	1.00
305_R	314_D	1.912	1.00
697_E	701_K	1.910	1.00
695_A	714_R	1.902	1.00
237_L	253_I	1.881	1.00
254_S	334_T	1.869	1.00
81_S	85_S	1.867	1.00
692_A	758_A	1.854	1.00
433_Q	436_K	1.851	1.00
63_S	140_D	1.841	1.00
294_G	300_E	1.840	1.00
279_E	283_Q	1.838	1.00
84_L	764_A	1.836	1.00
254_S	345_I	1.836	1.00
214_F	250_N	1.836	1.00
217_V	305_R	1.832	1.00
479_H	482_T	1.827	1.00
252_A	318_I	1.826	1.00
479_H	517_L	1.823	1.00
297_K	300_E	1.821	1.00
206_T	398_K	1.821	1.00
436_K	440_G	1.820	1.00
697_E	796_F	1.816	1.00
109_E	132_T	1.808	1.00
839_A	867_G	1.799	1.00
236_S	269_Q	1.790	1.00
443_W	589_V	1.787	1.00
64_I	144_L	1.782	1.00
161_T	540_T	1.781	1.00
365_P	372_D	1.779	1.00
265_Q	268_G	1.772	1.00
511_L	515_E	1.770	1.00
57_P	161_T	1.755	1.00
50_T	88_D	1.748	1.00
385_A	388_Q	1.748	1.00
264_V	278_V	1.745	1.00
170_G	174_G	1.741	1.00
494_E	498_K	1.740	1.00
263_L	270_A	1.734	1.00
109_E	125_K	1.733	1.00
239_I	253_I	1.732	1.00
82_K	704_E	1.729	1.00
266_I	269_Q	1.707	1.00
27_G	30_A	1.700	1.00
262_A	295_T	1.698	1.00
39_G	43_A	1.698	1.00
256_A	259_F	1.694	1.00
215_Q	236_S	1.693	1.00
700_L	704_E	1.691	1.00
262_A	292_I	1.685	1.00
247_L	310_F	1.672	1.00
504_G	507_A	1.668	1.00
598_G	641_S	1.668	1.00
79_V	89_S	1.667	1.00
688_A	723_M	1.661	1.00
166_I	500_V	1.661	1.00
23_K	26_P	1.657	1.00
131_A	157_M	1.644	1.00
180_K	478_V	1.641	1.00
217_V	307_T	1.638	1.00
282_M	290_Y	1.634	1.00
171_K	175_N	1.627	1.00
853_T	856_G	1.612	1.00
97_C	157_M	1.609	1.00
273_L	281_V	1.607	1.00
233_G	265_Q	1.606	1.00
215_Q	307_T	1.606	1.00
491_E	495_E	1.600	1.00
615_D	618_N	1.587	1.00
30_A	33_T	1.586	1.00
849_S	853_T	1.586	1.00
170_G	493_M	1.586	1.00
696_Q	758_A	1.584	1.00
489_T	492_L	1.579	1.00
785_Y	788_T	1.577	1.00
121_E	124_A	1.570	1.00
823_I	863_L	1.568	1.00
172_I	579_A	1.545	1.00
703_Y	711_V	1.541	1.00
255_I	331_A	1.536	1.00
374_V	379_A	1.536	1.00
437_E	578_T	1.535	1.00
155_L	158_D	1.532	1.00
546_D	581_K	1.531	1.00
82_K	85_S	1.528	1.00
23_K	27_G	1.528	1.00
31_R	772_D	1.527	1.00
761_R	789_G	1.526	1.00
482_T	517_L	1.526	1.00
234_P	270_A	1.524	1.00
255_I	317_A	1.518	1.00
210_I	247_L	1.515	1.00
24_R	27_G	1.507	1.00
263_L	296_V	1.502	1.00
143_R	618_N	1.499	1.00
439_K	453_E	1.495	1.00
800_D	803_A	1.495	1.00
238_V	271_V	1.493	1.00
254_S	320_G	1.489	1.00
364_L	367_T	1.488	1.00
284_R	397_E	1.477	1.00
213_A	236_S	1.476	1.00
438_I	456_V	1.474	1.00
696_Q	762_W	1.469	1.00
760_V	774_V	1.469	1.00
35_D	784_K	1.466	1.00
738_A	744_A	1.465	1.00
386_L	389_E	1.463	1.00
488_R	491_E	1.461	1.00
257_P	319_L	1.454	1.00
37_L	147_L	1.453	1.00
410_K	606_S	1.451	1.00
443_W	452_I	1.443	1.00
238_V	394_L	1.440	1.00
235_I	263_L	1.438	1.00
191_C	406_C	1.434	1.00
66_I	610_T	1.434	1.00
841_T	871_A	1.431	1.00
865_T	868_A	1.430	1.00
310_F	386_L	1.421	1.00
783_E	789_G	1.419	1.00
703_Y	766_I	1.413	0.99
145_G	769_F	1.412	0.99
337_G	356_P	1.409	0.99
319_L	349_Y	1.406	0.99
91_Y	148_G	1.399	0.99
662_L	665_N	1.399	0.99
482_T	520_E	1.398	0.99
216_A	304_L	1.391	0.99
548_R	551_F	1.385	0.99
480_K	523_Q	1.378	0.99
190_D	409_H	1.368	0.99
503_D	507_A	1.365	0.99
74_L	560_L	1.365	0.99
488_R	492_L	1.359	0.99
707_D	710_E	1.357	0.99
362_T	378_K	1.354	0.99
772_D	785_Y	1.353	0.99
615_D	642_D	1.352	0.99
301_L	304_L	1.346	0.99
374_V	378_K	1.344	0.99
258_D	297_K	1.342	0.99
320_G	344_V	1.336	0.99
264_V	292_I	1.330	0.99
208_P	379_A	1.326	0.99
161_T	543_S	1.325	0.99
172_I	576_I	1.323	0.99
444_I	588_Q	1.312	0.99
368_Y	371_L	1.311	0.99
507_A	511_L	1.305	0.99
254_S	318_I	1.292	0.99
554_H	583_K	1.291	0.99
826_A	831_K	1.290	0.99
850_A	853_T	1.286	0.99
849_S	872_D	1.285	0.99
334_T	346_G	1.283	0.99
85_S	704_E	1.281	0.99
503_D	510_D	1.279	0.99
45_K	83_G	1.269	0.99
756_A	778_L	1.266	0.99
595_T	638_M	1.265	0.99
186_H	415_F	1.252	0.99
164_N	167_R	1.250	0.99
251_R	354_A	1.249	0.99
554_H	581_K	1.248	0.99
208_P	396_V	1.248	0.99
541_H	576_I	1.246	0.99
434_S	575_M	1.245	0.99
369_P	372_D	1.242	0.99
25_E	622_A	1.239	0.99
616_V	645_L	1.234	0.99
258_D	299_A	1.231	0.99
296_V	300_E	1.230	0.99
256_A	321_D	1.229	0.99
693_K	696_Q	1.227	0.99
39_G	151_S	1.224	0.99
371_L	382_I	1.224	0.99
751_A	755_I	1.224	0.99
377_F	380_N	1.221	0.99
893_L	900_K	1.217	0.98
381_D	396_V	1.216	0.98
28_M	776_G	1.216	0.98
877_P	880_A	1.216	0.98
381_D	385_A	1.215	0.98
66_I	616_V	1.215	0.98
368_Y	372_D	1.211	0.98
188_C	406_C	1.211	0.98
456_V	571_M	1.209	0.98
495_E	498_K	1.204	0.98
571_M	575_M	1.201	0.98
764_A	787_F	1.199	0.98
442_Q	705_A	1.198	0.98
425_M	430_L	1.191	0.98
840_V	843_Y	1.189	0.98
312_G	370_T	1.189	0.98
574_L	585_P	1.188	0.98
503_D	511_L	1.188	0.98
278_V	282_M	1.185	0.98
499_R	507_A	1.181	0.98
306_F	315_V	1.181	0.98
490_L	494_E	1.180	0.98
217_V	314_D	1.179	0.98
539_S	576_I	1.179	0.98
700_L	793_E	1.179	0.98
320_G	334_T	1.175	0.98
235_I	270_A	1.175	0.98
357_V	376_V	1.174	0.98
711_V	766_I	1.174	0.98
614_Q	618_N	1.171	0.98
490_L	493_M	1.161	0.98
121_E	125_K	1.161	0.98
607_I	610_T	1.160	0.98
437_E	584_A	1.157	0.98
72_K	141_F	1.151	0.98
215_Q	234_P	1.145	0.98
388_Q	396_V	1.144	0.98
680_E	743_V	1.144	0.98
760_V	771_A	1.142	0.98
486_H	489_T	1.139	0.98
247_L	390_K	1.138	0.98
255_I	301_L	1.137	0.98
167_R	494_E	1.134	0.98
120_A	124_A	1.131	0.98
690_G	810_D	1.127	0.97
487_P	492_L	1.127	0.97
734_R	748_C	1.126	0.97
340_P	344_V	1.126	0.97
516_I	519_D	1.126	0.97
78_I	708_F	1.120	0.97
533_V	536_D	1.119	0.97
254_S	322_H	1.118	0.97
356_P	364_L	1.118	0.97
684_L	731_I	1.115	0.97
901_C	904_C	1.114	0.97
232_N	235_I	1.113	0.97
46_K	49_K	1.112	0.97
160_K	501_E	1.111	0.97
658_T	728_L	1.110	0.97
296_V	301_L	1.109	0.97
260_D	276_D	1.107	0.97
694_A	810_D	1.106	0.97
183_K	463_C	1.106	0.97
583_K	587_R	1.102	0.97
192_R	360_D	1.101	0.97
337_G	353_T	1.097	0.97
371_L	374_V	1.096	0.97
546_D	549_P	1.095	0.97
266_I	271_V	1.094	0.97
249_A	363_Y	1.093	0.97
54_H	540_T	1.093	0.97
252_A	346_G	1.092	0.97
681_M	689_V	1.091	0.97
200_V	413_I	1.091	0.97
423_V	464_I	1.091	0.97
514_K	523_Q	1.087	0.97
811_E	851_K	1.087	0.97
275_K	292_I	1.086	0.97
344_V	347_Q	1.085	0.97
45_K	790_E	1.085	0.97
44_A	790_E	1.084	0.97
689_V	754_H	1.084	0.97
669_F	750_T	1.083	0.97
676_V	681_M	1.083	0.97
292_I	295_T	1.082	0.97
453_E	457_A	1.081	0.97
681_M	751_A	1.080	0.97
211_D	284_R	1.078	0.97
113_P	116_K	1.077	0.97
497_A	501_E	1.074	0.97
31_R	37_L	1.073	0.97
446_D	449_Q	1.073	0.97
299_A	302_E	1.070	0.97
168_A	580_M	1.070	0.97
376_V	414_I	1.069	0.97
213_A	271_V	1.067	0.96
632_T	638_M	1.067	0.96
452_I	589_V	1.061	0.96
479_H	483_E	1.060	0.96
168_A	535_F	1.056	0.96
498_K	501_E	1.054	0.96
165_I	531_L	1.048	0.96
489_T	493_M	1.041	0.96
135_D	139_K	1.040	0.96
450_A	454_S	1.035	0.96
479_H	524_Y	1.034	0.96
362_T	375_N	1.031	0.96
498_K	502_V	1.031	0.96
499_R	503_D	1.030	0.96
305_R	316_P	1.029	0.96
237_L	272_I	1.028	0.96
255_I	319_L	1.027	0.96
873_Y	876_A	1.026	0.96
839_A	894_S	1.025	0.96
152_H	158_D	1.024	0.96
860_R	868_A	1.022	0.96
64_I	68_H	1.021	0.95
251_R	352_E	1.020	0.95
577_S	581_K	1.020	0.95
85_S	791_W	1.018	0.95
247_L	383_V	1.016	0.95
35_D	785_Y	1.015	0.95
512_D	515_E	1.013	0.95
180_K	419_P	1.013	0.95
210_I	384_V	1.013	0.95
758_A	762_W	1.012	0.95
763_M	767_L	1.010	0.95
695_A	718_F	1.008	0.95
216_A	237_L	1.007	0.95
560_L	592_H	1.007	0.95
334_T	345_I	1.003	0.95
616_V	625_L	1.003	0.95
844_A	852_L	1.003	0.95
696_Q	794_G	1.002	0.95
812_L	862_V	1.001	0.95
678_P	681_M	1.001	0.95
760_V	786_V	1.000	0.95
210_I	393_L	0.999	0.95
495_E	499_R	0.998	0.95
588_Q	706_Y	0.998	0.95
738_A	742_S	0.997	0.95
619_K	646_K	0.996	0.95
384_V	396_V	0.995	0.95
257_P	299_A	0.995	0.95
662_L	666_L	0.994	0.95
404_P	415_F	0.993	0.95
274_A	277_L	0.992	0.95
147_L	787_F	0.991	0.95
859_L	868_A	0.990	0.95
822_V	826_A	0.989	0.95
890_K	894_S	0.984	0.94
674_D	741_D	0.982	0.94
745_R	749_Q	0.981	0.94
66_I	640_V	0.979	0.94
790_E	793_E	0.977	0.94
449_Q	453_E	0.976	0.94
441_V	584_A	0.976	0.94
681_M	747_S	0.975	0.94
131_A	134_V	0.974	0.94
545_V	556_A	0.974	0.94
825_Q	829_D	0.971	0.94
631_S	712_V	0.966	0.94
172_I	423_V	0.963	0.94
250_N	315_V	0.963	0.94
352_E	357_V	0.962	0.94
643_E	647_R	0.960	0.94
696_Q	792_Y	0.960	0.94
500_V	505_I	0.960	0.94
173_I	178_L	0.958	0.94
661_F	665_N	0.956	0.94
37_L	788_T	0.956	0.94
823_I	832_V	0.953	0.94
452_I	456_V	0.953	0.94
699_I	762_W	0.953	0.94
900_K	903_R	0.953	0.94
612_S	615_D	0.952	0.93
66_I	595_T	0.950	0.93
692_A	755_I	0.950	0.93
265_Q	293_L	0.949	0.93
856_G	860_R	0.949	0.93
663_L	667_N	0.948	0.93
492_L	497_A	0.946	0.93
690_G	799_A	0.946	0.93
84_L	787_F	0.945	0.93
878_A	881_Q	0.941	0.93
492_L	500_V	0.940	0.93
356_P	363_Y	0.939	0.93
193_S	409_H	0.938	0.93
284_R	395_H	0.938	0.93
516_I	520_E	0.937	0.93
640_V	645_L	0.937	0.93
303_L	349_Y	0.936	0.93
670_D	674_D	0.934	0.93
169_L	178_L	0.932	0.93
758_A	761_R	0.932	0.93
681_M	750_T	0.929	0.93
492_L	496_V	0.929	0.93
208_P	398_K	0.928	0.93
303_L	316_P	0.924	0.92
40_I	788_T	0.921	0.92
216_A	235_I	0.919	0.92
321_D	348_K	0.917	0.92
688_A	718_F	0.916	0.92
84_L	761_R	0.915	0.92
46_K	88_D	0.914	0.92
382_I	386_L	0.913	0.92
833_G	836_L	0.913	0.92
702_A	710_E	0.913	0.92
406_C	409_H	0.912	0.92
287_V	290_Y	0.912	0.92
203_Y	410_K	0.912	0.92
698_D	710_E	0.912	0.92
41_I	83_G	0.911	0.92
177_H	430_L	0.911	0.92
467_Q	529_D	0.910	0.92
659_A	777_Y	0.910	0.92
693_K	798_L	0.910	0.92
80_K	787_F	0.907	0.92
715_L	763_M	0.907	0.92
697_E	794_G	0.905	0.92
435_L	457_A	0.902	0.91
338_H	355_N	0.899	0.91
410_K	607_I	0.899	0.91
324_T	327_A	0.896	0.91
84_L	791_W	0.892	0.91
249_A	356_P	0.891	0.91
219_Q	304_L	0.889	0.91
819_V	840_V	0.888	0.91
754_H	792_Y	0.887	0.91
643_E	646_K	0.885	0.91
492_L	498_K	0.885	0.91
894_S	897_E	0.883	0.91
889_L	892_A	0.882	0.91
168_A	542_S	0.881	0.91
691_C	694_A	0.880	0.90
27_G	773_E	0.879	0.90
694_A	801_S	0.878	0.90
764_A	786_V	0.878	0.90
306_F	317_A	0.877	0.90
80_K	147_L	0.876	0.90
378_K	381_D	0.876	0.90
494_E	500_V	0.875	0.90
281_V	394_L	0.875	0.90
282_M	287_V	0.875	0.90
188_C	479_H	0.874	0.90
562_G	592_H	0.873	0.90
352_E	355_N	0.872	0.90
664_A	667_N	0.870	0.90
876_A	879_D	0.870	0.90
136_G	140_D	0.869	0.90
574_L	584_A	0.869	0.90
236_S	271_V	0.868	0.90
139_K	142_I	0.867	0.90
846_P	872_D	0.866	0.90
263_L	272_I	0.864	0.90
252_A	316_P	0.864	0.90
190_D	411_T	0.864	0.90
128_E	132_T	0.862	0.90
55_D	72_K	0.860	0.89
373_G	376_V	0.859	0.89
841_T	869_T	0.859	0.89
760_V	778_L	0.859	0.89
443_W	449_Q	0.858	0.89
494_E	497_A	0.858	0.89
435_L	453_E	0.855	0.89
52_I	553_G	0.855	0.89
257_P	302_E	0.854	0.89
237_L	306_F	0.854	0.89
517_L	521_A	0.854	0.89
50_T	553_G	0.849	0.89
218_D	305_R	0.848	0.89
481_D	523_Q	0.846	0.89
358_G	364_L	0.844	0.89
272_I	296_V	0.840	0.88
775_W	789_G	0.840	0.88
477_F	513_A	0.839	0.88
764_A	771_A	0.839	0.88
726_F	813_L	0.838	0.88
131_A	135_D	0.836	0.88
664_A	668_G	0.832	0.88
859_L	863_L	0.832	0.88
239_I	331_A	0.832	0.88
239_I	309_P	0.829	0.88
107_E	122_F	0.829	0.88
690_G	694_A	0.829	0.88
838_A	865_T	0.828	0.88
554_H	577_S	0.828	0.88
666_L	669_F	0.826	0.87
676_V	750_T	0.826	0.87
364_L	372_D	0.826	0.87
559_Y	573_S	0.826	0.87
503_D	506_Q	0.825	0.87
272_I	317_A	0.824	0.87
566_H	591_T	0.823	0.87
595_T	610_T	0.822	0.87
690_G	798_L	0.822	0.87
318_I	351_L	0.820	0.87
438_I	443_W	0.820	0.87
896_A	899_E	0.819	0.87
81_S	700_L	0.818	0.87
598_G	642_D	0.817	0.87
863_L	868_A	0.817	0.87
768_S	787_F	0.816	0.87
264_V	282_M	0.815	0.87
440_G	583_K	0.815	0.87
754_H	757_E	0.813	0.87
214_F	253_I	0.812	0.87
251_R	351_L	0.811	0.87
132_T	136_G	0.811	0.87
701_K	704_E	0.811	0.87
678_P	686_R	0.811	0.87
702_A	714_R	0.809	0.86
175_N	433_Q	0.809	0.86
140_D	612_S	0.809	0.86
508_W	511_L	0.807	0.86
477_F	496_V	0.807	0.86
252_A	351_L	0.806	0.86
259_F	274_A	0.804	0.86
479_H	523_Q	0.803	0.86
251_R	313_F	0.802	0.86
514_K	522_D	0.802	0.86
480_K	521_A	0.801	0.86
433_Q	437_E	0.801	0.86
492_L	501_E	0.799	0.86
237_L	255_I	0.798	0.86
219_Q	235_I	0.798	0.86
169_L	531_L	0.797	0.86
354_A	357_V	0.796	0.85
822_V	825_Q	0.795	0.85
194_A	467_Q	0.795	0.85
702_A	711_V	0.794	0.85
120_A	510_D	0.793	0.85
129_Y	133_Q	0.793	0.85
425_M	459_R	0.793	0.85
816_R	820_N	0.792	0.85
274_A	325_L	0.792	0.85
665_N	668_G	0.791	0.85
887_K	891_V	0.790	0.85
119_A	122_F	0.787	0.85
845_E	848_L	0.787	0.85
890_K	893_L	0.784	0.85
363_Y	379_A	0.784	0.85
856_G	870_V	0.783	0.85
318_I	322_H	0.783	0.85
48_K	790_E	0.783	0.85
663_L	666_L	0.782	0.84
795_L	798_L	0.781	0.84
318_I	349_Y	0.779	0.84
188_C	520_E	0.778	0.84
337_G	355_N	0.778	0.84
663_L	669_F	0.777	0.84
665_N	669_F	0.776	0.84
353_T	356_P	0.776	0.84
345_I	349_Y	0.776	0.84
264_V	290_Y	0.774	0.84
696_Q	700_L	0.774	0.84
435_L	439_K	0.774	0.84
209_S	399_M	0.773	0.84
665_N	752_L	0.773	0.84
485_L	488_R	0.773	0.84
434_S	571_M	0.773	0.84
818_E	822_V	0.771	0.84
302_E	348_K	0.770	0.84
848_L	851_K	0.770	0.84
66_I	612_S	0.770	0.84
40_I	785_Y	0.768	0.83
95_W	138_R	0.768	0.83
189_V	375_N	0.768	0.83
731_I	748_C	0.766	0.83
847_E	850_A	0.766	0.83
796_F	799_A	0.766	0.83
208_P	380_N	0.765	0.83
454_S	457_A	0.765	0.83
205_K	405_C	0.765	0.83
432_A	435_L	0.765	0.83
693_K	697_E	0.765	0.83
188_C	482_T	0.764	0.83
249_A	338_H	0.764	0.83
127_R	131_A	0.764	0.83
37_L	784_K	0.764	0.83
42_R	83_G	0.762	0.83
26_P	618_N	0.761	0.83
280_S	283_Q	0.761	0.83
357_V	414_I	0.761	0.83
83_G	89_S	0.761	0.83
164_N	547_V	0.760	0.83
318_I	346_G	0.759	0.83
493_M	497_A	0.759	0.83
479_H	485_L	0.758	0.83
668_G	671_P	0.757	0.82
572_S	586_Y	0.757	0.82
135_D	142_I	0.757	0.82
681_M	754_H	0.756	0.82
694_A	698_D	0.755	0.82
775_W	783_E	0.753	0.82
26_P	30_A	0.751	0.82
140_D	614_Q	0.750	0.82
384_V	398_K	0.750	0.82
206_T	399_M	0.749	0.82
890_K	900_K	0.749	0.82
663_L	668_G	0.749	0.82
747_S	751_A	0.747	0.82
517_L	524_Y	0.747	0.82
713_Q	717_R	0.747	0.82
611_V	616_V	0.746	0.82
175_N	582_G	0.746	0.82
123_R	509_W	0.746	0.82
259_F	276_D	0.744	0.81
839_A	843_Y	0.743	0.81
115_E	469_T	0.743	0.81
216_A	306_F	0.742	0.81
676_V	743_V	0.742	0.81
369_P	386_L	0.741	0.81
841_T	894_S	0.741	0.81
43_A	47_G	0.740	0.81
117_F	125_K	0.739	0.81
630_A	766_I	0.738	0.81
438_I	452_I	0.738	0.81
409_H	479_H	0.736	0.81
138_R	150_W	0.736	0.81
675_M	750_T	0.735	0.81
642_D	646_K	0.735	0.81
316_P	349_Y	0.735	0.81
235_I	272_I	0.734	0.81
363_Y	371_L	0.734	0.81
264_V	273_L	0.734	0.81
857_D	860_R	0.733	0.80
441_V	574_L	0.733	0.80
285_I	394_L	0.733	0.80
74_L	592_H	0.731	0.80
627_L	712_V	0.729	0.80
220_D	234_P	0.729	0.80
563_S	566_H	0.729	0.80
827_R	833_G	0.727	0.80
441_V	585_P	0.726	0.80
836_L	866_S	0.726	0.80
514_K	525_V	0.726	0.80
876_A	880_A	0.726	0.80
873_Y	877_P	0.724	0.80
253_I	317_A	0.724	0.80
281_V	284_R	0.724	0.80
675_M	754_H	0.723	0.80
662_L	667_N	0.721	0.79
263_L	293_L	0.720	0.79
871_A	874_N	0.719	0.79
255_I	302_E	0.719	0.79
29_L	143_R	0.717	0.79
764_A	785_Y	0.716	0.79
820_N	824_E	0.716	0.79
837_E	895_K	0.715	0.79
364_L	368_Y	0.713	0.79
737_T	742_S	0.713	0.79
676_V	680_E	0.713	0.79
236_S	392_A	0.712	0.78
133_Q	136_G	0.711	0.78
603_M	609_N	0.711	0.78
510_D	513_A	0.710	0.78
165_I	168_A	0.710	0.78
172_I	178_L	0.709	0.78
452_I	566_H	0.709	0.78
459_R	575_M	0.708	0.78
748_C	751_A	0.708	0.78
431_R	457_A	0.707	0.78
303_L	319_L	0.707	0.78
482_T	485_L	0.706	0.78
381_D	384_V	0.706	0.78
308_H	311_M	0.705	0.78
72_K	93_P	0.705	0.78
655_I	763_M	0.705	0.78
888_G	891_V	0.705	0.78
876_A	890_K	0.705	0.78
682_V	748_C	0.704	0.78
890_K	897_E	0.704	0.78
136_G	139_K	0.702	0.78
692_A	696_Q	0.702	0.78
362_T	376_V	0.701	0.77
780_G	783_E	0.700	0.77
814_K	818_E	0.699	0.77
425_M	460_P	0.699	0.77
493_M	496_V	0.699	0.77
480_K	522_D	0.697	0.77
824_E	827_R	0.696	0.77
409_H	520_E	0.696	0.77
119_A	123_R	0.695	0.77
275_K	278_V	0.695	0.77
367_T	372_D	0.694	0.77
613_P	616_V	0.694	0.77
840_V	869_T	0.694	0.77
563_S	594_F	0.694	0.77
730_I	861_F	0.690	0.76
434_S	437_E	0.688	0.76
872_D	875_D	0.688	0.76
61_N	68_H	0.688	0.76
87_Y	704_E	0.687	0.76
134_V	138_R	0.687	0.76
668_G	749_Q	0.687	0.76
424_S	461_D	0.687	0.76
188_C	517_L	0.686	0.76
676_V	679_E	0.686	0.76
393_L	396_V	0.685	0.76
24_R	28_M	0.685	0.76
307_T	312_G	0.684	0.76
170_G	488_R	0.684	0.76
161_T	539_S	0.684	0.76
896_A	900_K	0.684	0.76
93_P	150_W	0.683	0.76
486_H	492_L	0.683	0.76
116_K	121_E	0.682	0.75
650_D	653_R	0.682	0.75
48_K	88_D	0.681	0.75
628_W	644_I	0.681	0.75
41_I	147_L	0.681	0.75
483_E	525_V	0.681	0.75
482_T	524_Y	0.681	0.75
216_A	317_A	0.680	0.75
420_Q	463_C	0.680	0.75
730_I	813_L	0.680	0.75
188_C	411_T	0.680	0.75
49_K	82_K	0.678	0.75
209_S	397_E	0.677	0.75
124_A	506_Q	0.676	0.75
835_S	864_L	0.676	0.75
385_A	396_V	0.676	0.75
191_C	411_T	0.676	0.75
320_G	324_T	0.676	0.75
441_V	589_V	0.675	0.75
754_H	795_L	0.674	0.75
214_F	315_V	0.673	0.74
542_S	581_K	0.673	0.74
746_R	750_T	0.673	0.74
757_E	760_V	0.670	0.74
610_T	616_V	0.670	0.74
693_K	799_A	0.669	0.74
811_E	847_E	0.669	0.74
262_A	273_L	0.668	0.74
84_L	790_E	0.668	0.74
306_F	331_A	0.666	0.74
47_G	50_T	0.665	0.74
36_D	43_A	0.663	0.73
105_K	133_Q	0.663	0.73
124_A	510_D	0.663	0.73
784_K	788_T	0.663	0.73
478_V	527_V	0.661	0.73
691_C	814_K	0.661	0.73
816_R	824_E	0.661	0.73
206_T	396_V	0.660	0.73
60_A	97_C	0.660	0.73
843_Y	871_A	0.660	0.73
683_V	686_R	0.660	0.73
132_T	135_D	0.659	0.73
603_M	610_T	0.659	0.73
59_Y	72_K	0.659	0.73
66_I	611_V	0.658	0.73
511_L	516_I	0.658	0.73
689_V	751_A	0.657	0.73
426_D	431_R	0.657	0.73
496_V	500_V	0.656	0.73
556_A	573_S	0.656	0.73
598_G	639_A	0.655	0.72
322_H	327_A	0.654	0.72
250_N	333_H	0.653	0.72
117_F	121_E	0.652	0.72
542_S	546_D	0.652	0.72
493_M	498_K	0.652	0.72
735_Q	752_L	0.652	0.72
698_D	701_K	0.651	0.72
832_V	838_A	0.651	0.72
456_V	575_M	0.651	0.72
81_S	791_W	0.651	0.72
798_L	801_S	0.650	0.72
772_D	776_G	0.647	0.72
811_E	815_V	0.647	0.72
279_E	282_M	0.647	0.72
561_E	565_Q	0.646	0.71
786_V	789_G	0.646	0.71
33_T	139_K	0.646	0.71
355_N	359_P	0.646	0.71
611_V	642_D	0.646	0.71
481_D	522_D	0.646	0.71
813_L	816_R	0.646	0.71
596_V	637_E	0.645	0.71
255_I	298_G	0.645	0.71
117_F	122_F	0.644	0.71
518_G	521_A	0.644	0.71
900_K	904_C	0.644	0.71
70_V	638_M	0.643	0.71
871_A	875_D	0.643	0.71
54_H	556_A	0.642	0.71
754_H	758_A	0.642	0.71
138_R	153_P	0.640	0.71
430_L	579_A	0.640	0.71
166_I	475_S	0.640	0.71
684_L	730_I	0.639	0.71
127_R	157_M	0.639	0.71
93_P	141_F	0.638	0.71
31_R	34_D	0.637	0.70
437_E	583_K	0.637	0.70
842_L	868_A	0.637	0.70
218_D	304_L	0.637	0.70
131_A	155_L	0.636	0.70
818_E	821_K	0.635	0.70
685_D	734_R	0.635	0.70
821_K	825_Q	0.634	0.70
490_L	497_A	0.633	0.70
511_L	514_K	0.632	0.70
311_M	370_T	0.631	0.70
839_A	897_E	0.631	0.70
743_V	747_S	0.631	0.70
142_I	151_S	0.630	0.70
487_P	496_V	0.630	0.70
28_M	772_D	0.630	0.70
594_F	602_K	0.629	0.69
269_Q	391_G	0.628	0.69
214_F	239_I	0.628	0.69
104_L	122_F	0.627	0.69
849_S	870_V	0.627	0.69
251_R	315_V	0.626	0.69
22_A	618_N	0.626	0.69
363_Y	368_Y	0.626	0.69
69_S	73_I	0.626	0.69
310_F	387_L	0.625	0.69
682_V	744_A	0.624	0.69
159_F	162_E	0.624	0.69
271_V	394_L	0.624	0.69
509_W	512_D	0.624	0.69
37_L	785_Y	0.623	0.69
141_F	150_W	0.623	0.69
141_F	146_V	0.622	0.69
693_K	754_H	0.621	0.68
278_V	292_I	0.621	0.68
678_P	797_G	0.621	0.68
431_R	435_L	0.621	0.68
82_K	700_L	0.621	0.68
630_A	703_Y	0.620	0.68
562_G	594_F	0.620	0.68
843_Y	890_K	0.620	0.68
512_D	516_I	0.620	0.68
662_L	669_F	0.619	0.68
211_D	238_V	0.618	0.68
262_A	296_V	0.618	0.68
212_V	239_I	0.618	0.68
368_Y	383_V	0.616	0.68
307_T	314_D	0.616	0.68
104_L	108_Q	0.613	0.67
547_V	550_E	0.613	0.67
35_D	776_G	0.612	0.67
520_E	524_Y	0.612	0.67
592_H	634_Y	0.610	0.67
257_P	322_H	0.610	0.67
259_F	324_T	0.610	0.67
671_P	753_Y	0.609	0.67
867_G	896_A	0.609	0.67
856_G	867_G	0.609	0.67
50_T	90_P	0.609	0.67
654_R	658_T	0.608	0.67
44_A	788_T	0.607	0.67
892_A	895_K	0.607	0.67
247_L	308_H	0.607	0.67
898_G	902_P	0.606	0.67
488_R	493_M	0.606	0.67
234_P	269_Q	0.606	0.67
692_A	718_F	0.606	0.67
186_H	413_I	0.606	0.67
343_Y	417_A	0.605	0.66
611_V	638_M	0.604	0.66
203_Y	405_C	0.604	0.66
220_D	304_L	0.604	0.66
659_A	760_V	0.604	0.66
492_L	495_E	0.604	0.66
682_V	743_V	0.603	0.66
771_A	786_V	0.603	0.66
237_L	301_L	0.602	0.66
207_S	403_Y	0.602	0.66
703_Y	708_F	0.602	0.66
851_K	854_A	0.602	0.66
212_V	247_L	0.601	0.66
678_P	798_L	0.600	0.66
855_L	863_L	0.600	0.66
371_L	389_E	0.600	0.66
115_E	118_T	0.600	0.66
793_E	796_F	0.599	0.66
481_D	484_E	0.599	0.66
365_P	781_E	0.598	0.66
484_E	519_D	0.598	0.66
64_I	612_S	0.598	0.66
409_H	517_L	0.597	0.65
497_A	513_A	0.597	0.65
105_K	109_E	0.596	0.65
823_I	838_A	0.596	0.65
41_I	787_F	0.596	0.65
676_V	747_S	0.595	0.65
620_L	645_L	0.594	0.65
322_H	341_D	0.594	0.65
217_V	234_P	0.594	0.65
819_V	863_L	0.594	0.65
371_L	383_V	0.593	0.65
164_N	501_E	0.593	0.65
172_I	580_M	0.593	0.65
24_R	773_E	0.593	0.65
215_Q	218_D	0.593	0.65
379_A	383_V	0.593	0.65
211_D	281_V	0.593	0.65
387_L	392_A	0.592	0.65
899_E	902_P	0.592	0.65
898_G	901_C	0.592	0.65
315_V	354_A	0.591	0.65
409_H	482_T	0.590	0.65
35_D	39_G	0.589	0.64
67_G	71_N	0.589	0.64
72_K	146_V	0.588	0.64
875_D	892_A	0.588	0.64
277_L	281_V	0.588	0.64
340_P	415_F	0.588	0.64
893_L	896_A	0.588	0.64
253_I	309_P	0.587	0.64
49_K	88_D	0.587	0.64
146_V	150_W	0.586	0.64
280_S	326_D	0.586	0.64
62_G	68_H	0.586	0.64
77_I	703_Y	0.586	0.64
51_F	78_I	0.585	0.64
476_L	485_L	0.585	0.64
688_A	751_A	0.585	0.64
77_I	766_I	0.585	0.64
587_R	607_I	0.584	0.64
689_V	798_L	0.583	0.64
93_P	153_P	0.583	0.64
481_D	485_L	0.583	0.64
59_Y	102_I	0.582	0.63
839_A	842_L	0.582	0.63
381_D	398_K	0.582	0.63
56_G	75_K	0.582	0.63
435_L	456_V	0.582	0.63
403_Y	415_F	0.582	0.63
817_G	820_N	0.582	0.63
372_D	376_V	0.581	0.63
839_A	898_G	0.581	0.63
459_R	571_M	0.579	0.63
163_A	501_E	0.579	0.63
16_P	777_Y	0.579	0.63
365_P	369_P	0.579	0.63
677_K	681_M	0.578	0.63
208_P	381_D	0.578	0.63
692_A	762_W	0.578	0.63
60_A	68_H	0.578	0.63
318_I	348_K	0.577	0.63
731_I	734_R	0.577	0.63
356_P	379_A	0.577	0.63
693_K	794_G	0.577	0.63
540_T	544_V	0.576	0.63
703_Y	791_W	0.576	0.63
234_P	268_G	0.576	0.63
66_I	73_I	0.575	0.63
840_V	867_G	0.575	0.63
19_G	22_A	0.574	0.62
338_H	356_P	0.574	0.62
826_A	893_L	0.574	0.62
610_T	613_P	0.574	0.62
63_S	133_Q	0.574	0.62
251_R	346_G	0.573	0.62
812_L	824_E	0.573	0.62
177_H	427_Q	0.573	0.62
213_A	394_L	0.573	0.62
655_I	719_C	0.572	0.62
799_A	803_A	0.572	0.62
796_F	800_D	0.572	0.62
650_D	654_R	0.570	0.62
699_I	715_L	0.570	0.62
171_K	580_M	0.570	0.62
669_F	749_Q	0.570	0.62
437_E	441_V	0.569	0.62
681_M	686_R	0.569	0.62
68_H	596_V	0.569	0.62
867_G	897_E	0.569	0.62
710_E	714_R	0.569	0.62
513_A	526_K	0.568	0.62
450_A	453_E	0.568	0.62
831_K	893_L	0.568	0.62
845_E	888_G	0.568	0.62
79_V	83_G	0.568	0.62
168_A	172_I	0.568	0.62
50_T	87_Y	0.567	0.61
65_H	71_N	0.566	0.61
258_D	321_D	0.565	0.61
477_F	517_L	0.565	0.61
889_L	899_E	0.563	0.61
776_G	779_P	0.563	0.61
715_L	762_W	0.563	0.61
87_Y	90_P	0.562	0.61
490_L	496_V	0.562	0.61
341_D	345_I	0.562	0.61
688_A	747_S	0.561	0.61
756_A	774_V	0.561	0.61
352_E	356_P	0.560	0.61
674_D	740_A	0.560	0.61
128_E	131_A	0.559	0.60
438_I	449_Q	0.559	0.60
52_I	90_P	0.559	0.60
170_G	497_A	0.558	0.60
500_V	503_D	0.558	0.60
682_V	747_S	0.558	0.60
162_E	459_R	0.558	0.60
844_A	849_S	0.558	0.60
16_P	19_G	0.557	0.60
185_V	194_A	0.557	0.60
546_D	550_E	0.557	0.60
734_R	738_A	0.557	0.60
687_W	691_C	0.557	0.60
353_T	357_V	0.556	0.60
123_R	506_Q	0.556	0.60
42_R	47_G	0.556	0.60
690_G	693_K	0.556	0.60
734_R	744_A	0.556	0.60
79_V	84_L	0.555	0.60
55_D	59_Y	0.554	0.60
887_K	890_K	0.554	0.60
818_E	891_V	0.554	0.60
143_R	622_A	0.554	0.60
698_D	702_A	0.554	0.60
811_E	848_L	0.553	0.60
139_K	618_N	0.553	0.60
560_L	590_L	0.552	0.59
26_P	143_R	0.552	0.59
216_A	219_Q	0.552	0.59
435_L	438_I	0.552	0.59
690_G	800_D	0.551	0.59
144_L	625_L	0.551	0.59
273_L	285_I	0.551	0.59
767_L	770_T	0.550	0.59
502_V	507_A	0.550	0.59
563_S	637_E	0.550	0.59
553_G	587_R	0.550	0.59
324_T	334_T	0.550	0.59
273_L	400_Q	0.549	0.59
746_R	749_Q	0.549	0.59
830_K	833_G	0.549	0.59
719_C	759_L	0.549	0.59
617_M	622_A	0.549	0.59
27_G	31_R	0.548	0.59
542_S	548_R	0.548	0.59
401_H	404_P	0.548	0.59
843_Y	873_Y	0.547	0.59
895_K	898_G	0.547	0.59
839_A	896_A	0.547	0.59
42_R	45_K	0.547	0.59
104_L	117_F	0.547	0.59
58_P	62_G	0.547	0.59
711_V	721_V	0.547	0.59
336_P	346_G	0.546	0.59
482_T	487_P	0.546	0.59
717_R	720_S	0.546	0.59
21_L	652_Y	0.546	0.59
841_T	892_A	0.545	0.58
425_M	575_M	0.545	0.58
165_I	472_V	0.544	0.58
487_P	491_E	0.544	0.58
876_A	881_Q	0.544	0.58
74_L	78_I	0.544	0.58
667_N	749_Q	0.544	0.58
736_Y	749_Q	0.544	0.58
160_K	164_N	0.544	0.58
736_Y	745_R	0.543	0.58
507_A	510_D	0.543	0.58
716_M	720_S	0.542	0.58
652_Y	767_L	0.542	0.58
62_G	95_W	0.542	0.58
15_F	777_Y	0.542	0.58
767_L	771_A	0.542	0.58
733_D	737_T	0.542	0.58
256_A	325_L	0.542	0.58
529_D	533_V	0.542	0.58
270_A	291_T	0.541	0.58
603_M	611_V	0.541	0.58
231_V	235_I	0.540	0.58
187_W	594_F	0.540	0.58
479_H	521_A	0.540	0.58
682_V	731_I	0.540	0.58
695_A	699_I	0.539	0.58
492_L	499_R	0.539	0.58
247_L	386_L	0.539	0.58
343_Y	353_T	0.539	0.58
104_L	190_D	0.539	0.58
251_R	336_P	0.539	0.58
826_A	830_K	0.538	0.58
702_A	707_D	0.538	0.58
730_I	862_V	0.538	0.58
564_D	594_F	0.537	0.57
69_S	144_L	0.537	0.57
558_M	706_Y	0.537	0.57
891_V	895_K	0.537	0.57
278_V	290_Y	0.537	0.57
877_P	890_K	0.537	0.57
48_K	85_S	0.536	0.57
475_S	493_M	0.536	0.57
685_D	747_S	0.536	0.57
846_P	849_S	0.536	0.57
295_T	298_G	0.535	0.57
28_M	31_R	0.534	0.57
845_E	852_L	0.534	0.57
142_I	150_W	0.534	0.57
610_T	640_V	0.533	0.57
875_D	879_D	0.532	0.57
64_I	137_Q	0.532	0.57
877_P	881_Q	0.532	0.57
84_L	789_G	0.532	0.57
773_E	777_Y	0.531	0.57
286_G	395_H	0.530	0.56
307_T	311_M	0.530	0.56
661_F	728_L	0.529	0.56
699_I	711_V	0.529	0.56
891_V	894_S	0.528	0.56
238_V	281_V	0.528	0.56
355_N	363_Y	0.528	0.56
506_Q	510_D	0.527	0.56
438_I	441_V	0.527	0.56
753_Y	757_E	0.527	0.56
702_A	705_A	0.527	0.56
656_R	770_T	0.526	0.56
37_L	40_I	0.526	0.56
595_T	640_V	0.526	0.56
826_A	829_D	0.526	0.56
361_G	365_P	0.526	0.56
434_S	459_R	0.525	0.56
179_H	424_S	0.525	0.56
252_A	334_T	0.524	0.56
715_L	759_L	0.524	0.56
102_I	130_A	0.523	0.55
275_K	279_E	0.523	0.55
834_G	837_E	0.522	0.55
64_I	610_T	0.522	0.55
797_G	800_D	0.521	0.55
499_R	502_V	0.521	0.55
71_N	562_G	0.520	0.55
563_S	590_L	0.520	0.55
216_A	220_D	0.520	0.55
54_H	573_S	0.520	0.55
482_T	522_D	0.520	0.55
106_V	129_Y	0.520	0.55
726_F	730_I	0.520	0.55
444_I	452_I	0.519	0.55
194_A	463_C	0.519	0.55
337_G	354_A	0.519	0.55
653_R	661_F	0.519	0.55
161_T	165_I	0.519	0.55
207_S	401_H	0.518	0.55
85_S	793_E	0.518	0.55
510_D	515_E	0.517	0.55
285_I	395_H	0.517	0.55
678_P	682_V	0.517	0.55
311_M	315_V	0.517	0.55
309_P	315_V	0.516	0.54
64_I	140_D	0.516	0.54
494_E	501_E	0.515	0.54
617_M	623_D	0.515	0.54
821_K	828_A	0.515	0.54
198_A	201_E	0.515	0.54
54_H	559_Y	0.514	0.54
479_H	516_I	0.514	0.54
641_S	644_I	0.513	0.54
39_G	44_A	0.513	0.54
606_S	610_T	0.513	0.54
758_A	794_G	0.512	0.54
77_I	708_F	0.512	0.54
718_F	723_M	0.512	0.54
149_D	551_F	0.511	0.54
699_I	714_R	0.511	0.54
669_F	746_R	0.510	0.54
45_K	49_K	0.510	0.54
370_T	389_E	0.510	0.54
172_I	586_Y	0.510	0.54
731_I	735_Q	0.510	0.54
855_L	858_E	0.509	0.53
170_G	494_E	0.509	0.53
311_M	369_P	0.509	0.53
890_K	895_K	0.509	0.53
662_L	668_G	0.508	0.53
319_L	322_H	0.508	0.53
157_M	165_I	0.508	0.53
420_Q	594_F	0.507	0.53
812_L	816_R	0.507	0.53
402_S	405_C	0.507	0.53
232_N	270_A	0.506	0.53
842_L	876_A	0.506	0.53
203_Y	400_Q	0.506	0.53
273_L	278_V	0.506	0.53
853_T	870_V	0.506	0.53
867_G	870_V	0.505	0.53
210_I	322_H	0.505	0.53
771_A	774_V	0.505	0.53
497_A	500_V	0.505	0.53
867_G	898_G	0.504	0.53
819_V	823_I	0.504	0.53
616_V	620_L	0.504	0.53
104_L	191_C	0.503	0.53
68_H	134_V	0.503	0.53
212_V	393_L	0.502	0.52
487_P	493_M	0.502	0.52
815_V	848_L	0.502	0.52
64_I	613_P	0.502	0.52
479_H	484_E	0.502	0.52
542_S	580_M	0.502	0.52
112_K	116_K	0.502	0.52
748_C	752_L	0.502	0.52
286_G	289_D	0.501	0.52
697_E	799_A	0.501	0.52
66_I	69_S	0.501	0.52
741_D	746_R	0.500	0.52
118_T	510_D	0.500	0.52
73_I	629_V	0.500	0.52

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ffyA	1	0.9659	100	0.141	Contact Map
1gaxA	1	0.8795	100	0.316	Contact Map
1ileA	1	0.8475	100	0.331	Contact Map
1wz2A	1	0.8955	100	0.355	Contact Map
1wkbA	1	0.7591	100	0.417	Contact Map
2v0cA	1	0.7239	100	0.452	Contact Map
4arcA	1	0.7377	100	0.469	Contact Map
3ziuA	1	0.6183	100	0.581	Contact Map
1rqgA	2	0.5693	100	0.676	Contact Map
4qreA	1	0.5352	100	0.68	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.02 seconds.