GREMLIN Database
SYI - Isoleucine--tRNA ligase
UniProt: P00956 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10492
Length: 938 (861)
Sequences: 4888 (2829)
Seq/√Len: 96.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
36_D39_G5.6641.00
265_Q291_T5.5871.00
260_D297_K5.2341.00
30_A34_D5.0581.00
275_K295_T4.9371.00
82_K87_Y4.6601.00
33_T142_I4.0941.00
262_A275_K3.8551.00
374_V382_I3.8071.00
439_K449_Q3.7911.00
135_D138_R3.7591.00
371_L386_L3.7291.00
171_K174_G3.6121.00
40_I784_K3.5681.00
346_G351_L3.3781.00
260_D275_K3.3701.00
85_S700_L3.3451.00
237_L317_A3.2101.00
302_E319_L3.1221.00
213_A269_Q3.0831.00
259_F325_L3.0711.00
601_R607_I2.9291.00
260_D295_T2.9241.00
757_E761_R2.8651.00
125_K128_E2.8221.00
105_K108_Q2.8071.00
188_C409_H2.7941.00
517_L520_E2.7911.00
253_I331_A2.7901.00
686_R800_D2.7561.00
557_D587_R2.7501.00
43_A46_K2.7201.00
619_K642_D2.7071.00
45_K48_K2.6461.00
442_Q588_Q2.6311.00
322_H345_I2.6261.00
598_G643_E2.6121.00
31_R35_D2.5841.00
763_M771_A2.5711.00
698_D714_R2.5391.00
370_T386_L2.5271.00
277_L280_S2.5011.00
31_R776_G2.4971.00
262_A278_V2.4961.00
677_K680_E2.4681.00
437_E440_G2.4641.00
659_A774_V2.4501.00
118_T121_E2.4431.00
302_E349_Y2.4151.00
432_A436_K2.4141.00
322_H334_T2.3921.00
80_K768_S2.3841.00
318_I345_I2.3161.00
29_L769_F2.3061.00
839_A869_T2.2821.00
270_A293_L2.2801.00
433_Q582_G2.2781.00
138_R151_S2.2591.00
206_T400_Q2.2581.00
138_R142_I2.2531.00
134_V155_L2.2441.00
237_L331_A2.2421.00
386_L390_K2.2021.00
51_F706_Y2.1981.00
20_D23_K2.1951.00
149_D152_H2.1891.00
167_R501_E2.1661.00
188_C191_C2.1631.00
385_A389_E2.1581.00
204_D402_S2.1521.00
276_D325_L2.1521.00
124_A128_E2.1491.00
701_K705_A2.1231.00
424_S427_Q2.1181.00
343_Y347_Q2.1081.00
49_K87_Y2.0951.00
42_R88_D2.0821.00
688_A755_I2.0771.00
480_K525_V2.0661.00
700_L791_W2.0651.00
265_Q270_A2.0621.00
253_I306_F2.0561.00
281_V285_I2.0541.00
558_M590_L2.0441.00
204_D400_Q2.0391.00
40_I43_A2.0351.00
615_D619_K2.0181.00
375_N378_K2.0161.00
63_S136_G1.9961.00
174_G490_L1.9861.00
358_G362_T1.9811.00
341_D344_V1.9741.00
320_G345_I1.9701.00
436_K439_K1.9611.00
167_R497_A1.9581.00
47_G88_D1.9581.00
479_H520_E1.9511.00
77_I630_A1.9461.00
215_Q392_A1.9371.00
81_S704_E1.9331.00
382_I385_A1.9321.00
558_M588_Q1.9321.00
263_L294_G1.9291.00
191_C409_H1.9151.00
846_P850_A1.9131.00
305_R314_D1.9121.00
697_E701_K1.9101.00
695_A714_R1.9021.00
237_L253_I1.8811.00
254_S334_T1.8691.00
81_S85_S1.8671.00
692_A758_A1.8541.00
433_Q436_K1.8511.00
63_S140_D1.8411.00
294_G300_E1.8401.00
279_E283_Q1.8381.00
84_L764_A1.8361.00
254_S345_I1.8361.00
214_F250_N1.8361.00
217_V305_R1.8321.00
479_H482_T1.8271.00
252_A318_I1.8261.00
479_H517_L1.8231.00
297_K300_E1.8211.00
206_T398_K1.8211.00
436_K440_G1.8201.00
697_E796_F1.8161.00
109_E132_T1.8081.00
839_A867_G1.7991.00
236_S269_Q1.7901.00
443_W589_V1.7871.00
64_I144_L1.7821.00
161_T540_T1.7811.00
365_P372_D1.7791.00
265_Q268_G1.7721.00
511_L515_E1.7701.00
57_P161_T1.7551.00
50_T88_D1.7481.00
385_A388_Q1.7481.00
264_V278_V1.7451.00
170_G174_G1.7411.00
494_E498_K1.7401.00
263_L270_A1.7341.00
109_E125_K1.7331.00
239_I253_I1.7321.00
82_K704_E1.7291.00
266_I269_Q1.7071.00
27_G30_A1.7001.00
262_A295_T1.6981.00
39_G43_A1.6981.00
256_A259_F1.6941.00
215_Q236_S1.6931.00
700_L704_E1.6911.00
262_A292_I1.6851.00
247_L310_F1.6721.00
504_G507_A1.6681.00
598_G641_S1.6681.00
79_V89_S1.6671.00
688_A723_M1.6611.00
166_I500_V1.6611.00
23_K26_P1.6571.00
131_A157_M1.6441.00
180_K478_V1.6411.00
217_V307_T1.6381.00
282_M290_Y1.6341.00
171_K175_N1.6271.00
853_T856_G1.6121.00
97_C157_M1.6091.00
273_L281_V1.6071.00
233_G265_Q1.6061.00
215_Q307_T1.6061.00
491_E495_E1.6001.00
615_D618_N1.5871.00
30_A33_T1.5861.00
849_S853_T1.5861.00
170_G493_M1.5861.00
696_Q758_A1.5841.00
489_T492_L1.5791.00
785_Y788_T1.5771.00
121_E124_A1.5701.00
823_I863_L1.5681.00
172_I579_A1.5451.00
703_Y711_V1.5411.00
255_I331_A1.5361.00
374_V379_A1.5361.00
437_E578_T1.5351.00
155_L158_D1.5321.00
546_D581_K1.5311.00
82_K85_S1.5281.00
23_K27_G1.5281.00
31_R772_D1.5271.00
761_R789_G1.5261.00
482_T517_L1.5261.00
234_P270_A1.5241.00
255_I317_A1.5181.00
210_I247_L1.5151.00
24_R27_G1.5071.00
263_L296_V1.5021.00
143_R618_N1.4991.00
439_K453_E1.4951.00
800_D803_A1.4951.00
238_V271_V1.4931.00
254_S320_G1.4891.00
364_L367_T1.4881.00
284_R397_E1.4771.00
213_A236_S1.4761.00
438_I456_V1.4741.00
696_Q762_W1.4691.00
760_V774_V1.4691.00
35_D784_K1.4661.00
738_A744_A1.4651.00
386_L389_E1.4631.00
488_R491_E1.4611.00
257_P319_L1.4541.00
37_L147_L1.4531.00
410_K606_S1.4511.00
443_W452_I1.4431.00
238_V394_L1.4401.00
235_I263_L1.4381.00
191_C406_C1.4341.00
66_I610_T1.4341.00
841_T871_A1.4311.00
865_T868_A1.4301.00
310_F386_L1.4211.00
783_E789_G1.4191.00
703_Y766_I1.4130.99
145_G769_F1.4120.99
337_G356_P1.4090.99
319_L349_Y1.4060.99
91_Y148_G1.3990.99
662_L665_N1.3990.99
482_T520_E1.3980.99
216_A304_L1.3910.99
548_R551_F1.3850.99
480_K523_Q1.3780.99
190_D409_H1.3680.99
503_D507_A1.3650.99
74_L560_L1.3650.99
488_R492_L1.3590.99
707_D710_E1.3570.99
362_T378_K1.3540.99
772_D785_Y1.3530.99
615_D642_D1.3520.99
301_L304_L1.3460.99
374_V378_K1.3440.99
258_D297_K1.3420.99
320_G344_V1.3360.99
264_V292_I1.3300.99
208_P379_A1.3260.99
161_T543_S1.3250.99
172_I576_I1.3230.99
444_I588_Q1.3120.99
368_Y371_L1.3110.99
507_A511_L1.3050.99
254_S318_I1.2920.99
554_H583_K1.2910.99
826_A831_K1.2900.99
850_A853_T1.2860.99
849_S872_D1.2850.99
334_T346_G1.2830.99
85_S704_E1.2810.99
503_D510_D1.2790.99
45_K83_G1.2690.99
756_A778_L1.2660.99
595_T638_M1.2650.99
186_H415_F1.2520.99
164_N167_R1.2500.99
251_R354_A1.2490.99
554_H581_K1.2480.99
208_P396_V1.2480.99
541_H576_I1.2460.99
434_S575_M1.2450.99
369_P372_D1.2420.99
25_E622_A1.2390.99
616_V645_L1.2340.99
258_D299_A1.2310.99
296_V300_E1.2300.99
256_A321_D1.2290.99
693_K696_Q1.2270.99
39_G151_S1.2240.99
371_L382_I1.2240.99
751_A755_I1.2240.99
377_F380_N1.2210.99
893_L900_K1.2170.98
381_D396_V1.2160.98
28_M776_G1.2160.98
877_P880_A1.2160.98
381_D385_A1.2150.98
66_I616_V1.2150.98
368_Y372_D1.2110.98
188_C406_C1.2110.98
456_V571_M1.2090.98
495_E498_K1.2040.98
571_M575_M1.2010.98
764_A787_F1.1990.98
442_Q705_A1.1980.98
425_M430_L1.1910.98
840_V843_Y1.1890.98
312_G370_T1.1890.98
574_L585_P1.1880.98
503_D511_L1.1880.98
278_V282_M1.1850.98
499_R507_A1.1810.98
306_F315_V1.1810.98
490_L494_E1.1800.98
217_V314_D1.1790.98
539_S576_I1.1790.98
700_L793_E1.1790.98
320_G334_T1.1750.98
235_I270_A1.1750.98
357_V376_V1.1740.98
711_V766_I1.1740.98
614_Q618_N1.1710.98
490_L493_M1.1610.98
121_E125_K1.1610.98
607_I610_T1.1600.98
437_E584_A1.1570.98
72_K141_F1.1510.98
215_Q234_P1.1450.98
388_Q396_V1.1440.98
680_E743_V1.1440.98
760_V771_A1.1420.98
486_H489_T1.1390.98
247_L390_K1.1380.98
255_I301_L1.1370.98
167_R494_E1.1340.98
120_A124_A1.1310.98
690_G810_D1.1270.97
487_P492_L1.1270.97
734_R748_C1.1260.97
340_P344_V1.1260.97
516_I519_D1.1260.97
78_I708_F1.1200.97
533_V536_D1.1190.97
254_S322_H1.1180.97
356_P364_L1.1180.97
684_L731_I1.1150.97
901_C904_C1.1140.97
232_N235_I1.1130.97
46_K49_K1.1120.97
160_K501_E1.1110.97
658_T728_L1.1100.97
296_V301_L1.1090.97
260_D276_D1.1070.97
694_A810_D1.1060.97
183_K463_C1.1060.97
583_K587_R1.1020.97
192_R360_D1.1010.97
337_G353_T1.0970.97
371_L374_V1.0960.97
546_D549_P1.0950.97
266_I271_V1.0940.97
249_A363_Y1.0930.97
54_H540_T1.0930.97
252_A346_G1.0920.97
681_M689_V1.0910.97
200_V413_I1.0910.97
423_V464_I1.0910.97
514_K523_Q1.0870.97
811_E851_K1.0870.97
275_K292_I1.0860.97
344_V347_Q1.0850.97
45_K790_E1.0850.97
44_A790_E1.0840.97
689_V754_H1.0840.97
669_F750_T1.0830.97
676_V681_M1.0830.97
292_I295_T1.0820.97
453_E457_A1.0810.97
681_M751_A1.0800.97
211_D284_R1.0780.97
113_P116_K1.0770.97
497_A501_E1.0740.97
31_R37_L1.0730.97
446_D449_Q1.0730.97
299_A302_E1.0700.97
168_A580_M1.0700.97
376_V414_I1.0690.97
213_A271_V1.0670.96
632_T638_M1.0670.96
452_I589_V1.0610.96
479_H483_E1.0600.96
168_A535_F1.0560.96
498_K501_E1.0540.96
165_I531_L1.0480.96
489_T493_M1.0410.96
135_D139_K1.0400.96
450_A454_S1.0350.96
479_H524_Y1.0340.96
362_T375_N1.0310.96
498_K502_V1.0310.96
499_R503_D1.0300.96
305_R316_P1.0290.96
237_L272_I1.0280.96
255_I319_L1.0270.96
873_Y876_A1.0260.96
839_A894_S1.0250.96
152_H158_D1.0240.96
860_R868_A1.0220.96
64_I68_H1.0210.95
251_R352_E1.0200.95
577_S581_K1.0200.95
85_S791_W1.0180.95
247_L383_V1.0160.95
35_D785_Y1.0150.95
512_D515_E1.0130.95
180_K419_P1.0130.95
210_I384_V1.0130.95
758_A762_W1.0120.95
763_M767_L1.0100.95
695_A718_F1.0080.95
216_A237_L1.0070.95
560_L592_H1.0070.95
334_T345_I1.0030.95
616_V625_L1.0030.95
844_A852_L1.0030.95
696_Q794_G1.0020.95
812_L862_V1.0010.95
678_P681_M1.0010.95
760_V786_V1.0000.95
210_I393_L0.9990.95
495_E499_R0.9980.95
588_Q706_Y0.9980.95
738_A742_S0.9970.95
619_K646_K0.9960.95
384_V396_V0.9950.95
257_P299_A0.9950.95
662_L666_L0.9940.95
404_P415_F0.9930.95
274_A277_L0.9920.95
147_L787_F0.9910.95
859_L868_A0.9900.95
822_V826_A0.9890.95
890_K894_S0.9840.94
674_D741_D0.9820.94
745_R749_Q0.9810.94
66_I640_V0.9790.94
790_E793_E0.9770.94
449_Q453_E0.9760.94
441_V584_A0.9760.94
681_M747_S0.9750.94
131_A134_V0.9740.94
545_V556_A0.9740.94
825_Q829_D0.9710.94
631_S712_V0.9660.94
172_I423_V0.9630.94
250_N315_V0.9630.94
352_E357_V0.9620.94
643_E647_R0.9600.94
696_Q792_Y0.9600.94
500_V505_I0.9600.94
173_I178_L0.9580.94
661_F665_N0.9560.94
37_L788_T0.9560.94
823_I832_V0.9530.94
452_I456_V0.9530.94
699_I762_W0.9530.94
900_K903_R0.9530.94
612_S615_D0.9520.93
66_I595_T0.9500.93
692_A755_I0.9500.93
265_Q293_L0.9490.93
856_G860_R0.9490.93
663_L667_N0.9480.93
492_L497_A0.9460.93
690_G799_A0.9460.93
84_L787_F0.9450.93
878_A881_Q0.9410.93
492_L500_V0.9400.93
356_P363_Y0.9390.93
193_S409_H0.9380.93
284_R395_H0.9380.93
516_I520_E0.9370.93
640_V645_L0.9370.93
303_L349_Y0.9360.93
670_D674_D0.9340.93
169_L178_L0.9320.93
758_A761_R0.9320.93
681_M750_T0.9290.93
492_L496_V0.9290.93
208_P398_K0.9280.93
303_L316_P0.9240.92
40_I788_T0.9210.92
216_A235_I0.9190.92
321_D348_K0.9170.92
688_A718_F0.9160.92
84_L761_R0.9150.92
46_K88_D0.9140.92
382_I386_L0.9130.92
833_G836_L0.9130.92
702_A710_E0.9130.92
406_C409_H0.9120.92
287_V290_Y0.9120.92
203_Y410_K0.9120.92
698_D710_E0.9120.92
41_I83_G0.9110.92
177_H430_L0.9110.92
467_Q529_D0.9100.92
659_A777_Y0.9100.92
693_K798_L0.9100.92
80_K787_F0.9070.92
715_L763_M0.9070.92
697_E794_G0.9050.92
435_L457_A0.9020.91
338_H355_N0.8990.91
410_K607_I0.8990.91
324_T327_A0.8960.91
84_L791_W0.8920.91
249_A356_P0.8910.91
219_Q304_L0.8890.91
819_V840_V0.8880.91
754_H792_Y0.8870.91
643_E646_K0.8850.91
492_L498_K0.8850.91
894_S897_E0.8830.91
889_L892_A0.8820.91
168_A542_S0.8810.91
691_C694_A0.8800.90
27_G773_E0.8790.90
694_A801_S0.8780.90
764_A786_V0.8780.90
306_F317_A0.8770.90
80_K147_L0.8760.90
378_K381_D0.8760.90
494_E500_V0.8750.90
281_V394_L0.8750.90
282_M287_V0.8750.90
188_C479_H0.8740.90
562_G592_H0.8730.90
352_E355_N0.8720.90
664_A667_N0.8700.90
876_A879_D0.8700.90
136_G140_D0.8690.90
574_L584_A0.8690.90
236_S271_V0.8680.90
139_K142_I0.8670.90
846_P872_D0.8660.90
263_L272_I0.8640.90
252_A316_P0.8640.90
190_D411_T0.8640.90
128_E132_T0.8620.90
55_D72_K0.8600.89
373_G376_V0.8590.89
841_T869_T0.8590.89
760_V778_L0.8590.89
443_W449_Q0.8580.89
494_E497_A0.8580.89
435_L453_E0.8550.89
52_I553_G0.8550.89
257_P302_E0.8540.89
237_L306_F0.8540.89
517_L521_A0.8540.89
50_T553_G0.8490.89
218_D305_R0.8480.89
481_D523_Q0.8460.89
358_G364_L0.8440.89
272_I296_V0.8400.88
775_W789_G0.8400.88
477_F513_A0.8390.88
764_A771_A0.8390.88
726_F813_L0.8380.88
131_A135_D0.8360.88
664_A668_G0.8320.88
859_L863_L0.8320.88
239_I331_A0.8320.88
239_I309_P0.8290.88
107_E122_F0.8290.88
690_G694_A0.8290.88
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736_Y745_R0.5430.58
507_A510_D0.5430.58
716_M720_S0.5420.58
652_Y767_L0.5420.58
62_G95_W0.5420.58
15_F777_Y0.5420.58
767_L771_A0.5420.58
733_D737_T0.5420.58
256_A325_L0.5420.58
529_D533_V0.5420.58
270_A291_T0.5410.58
603_M611_V0.5410.58
231_V235_I0.5400.58
187_W594_F0.5400.58
479_H521_A0.5400.58
682_V731_I0.5400.58
695_A699_I0.5390.58
492_L499_R0.5390.58
247_L386_L0.5390.58
343_Y353_T0.5390.58
104_L190_D0.5390.58
251_R336_P0.5390.58
826_A830_K0.5380.58
702_A707_D0.5380.58
730_I862_V0.5380.58
564_D594_F0.5370.57
69_S144_L0.5370.57
558_M706_Y0.5370.57
891_V895_K0.5370.57
278_V290_Y0.5370.57
877_P890_K0.5370.57
48_K85_S0.5360.57
475_S493_M0.5360.57
685_D747_S0.5360.57
846_P849_S0.5360.57
295_T298_G0.5350.57
28_M31_R0.5340.57
845_E852_L0.5340.57
142_I150_W0.5340.57
610_T640_V0.5330.57
875_D879_D0.5320.57
64_I137_Q0.5320.57
877_P881_Q0.5320.57
84_L789_G0.5320.57
773_E777_Y0.5310.57
286_G395_H0.5300.56
307_T311_M0.5300.56
661_F728_L0.5290.56
699_I711_V0.5290.56
891_V894_S0.5280.56
238_V281_V0.5280.56
355_N363_Y0.5280.56
506_Q510_D0.5270.56
438_I441_V0.5270.56
753_Y757_E0.5270.56
702_A705_A0.5270.56
656_R770_T0.5260.56
37_L40_I0.5260.56
595_T640_V0.5260.56
826_A829_D0.5260.56
361_G365_P0.5260.56
434_S459_R0.5250.56
179_H424_S0.5250.56
252_A334_T0.5240.56
715_L759_L0.5240.56
102_I130_A0.5230.55
275_K279_E0.5230.55
834_G837_E0.5220.55
64_I610_T0.5220.55
797_G800_D0.5210.55
499_R502_V0.5210.55
71_N562_G0.5200.55
563_S590_L0.5200.55
216_A220_D0.5200.55
54_H573_S0.5200.55
482_T522_D0.5200.55
106_V129_Y0.5200.55
726_F730_I0.5200.55
444_I452_I0.5190.55
194_A463_C0.5190.55
337_G354_A0.5190.55
653_R661_F0.5190.55
161_T165_I0.5190.55
207_S401_H0.5180.55
85_S793_E0.5180.55
510_D515_E0.5170.55
285_I395_H0.5170.55
678_P682_V0.5170.55
311_M315_V0.5170.55
309_P315_V0.5160.54
64_I140_D0.5160.54
494_E501_E0.5150.54
617_M623_D0.5150.54
821_K828_A0.5150.54
198_A201_E0.5150.54
54_H559_Y0.5140.54
479_H516_I0.5140.54
641_S644_I0.5130.54
39_G44_A0.5130.54
606_S610_T0.5130.54
758_A794_G0.5120.54
77_I708_F0.5120.54
718_F723_M0.5120.54
149_D551_F0.5110.54
699_I714_R0.5110.54
669_F746_R0.5100.54
45_K49_K0.5100.54
370_T389_E0.5100.54
172_I586_Y0.5100.54
731_I735_Q0.5100.54
855_L858_E0.5090.53
170_G494_E0.5090.53
311_M369_P0.5090.53
890_K895_K0.5090.53
662_L668_G0.5080.53
319_L322_H0.5080.53
157_M165_I0.5080.53
420_Q594_F0.5070.53
812_L816_R0.5070.53
402_S405_C0.5070.53
232_N270_A0.5060.53
842_L876_A0.5060.53
203_Y400_Q0.5060.53
273_L278_V0.5060.53
853_T870_V0.5060.53
867_G870_V0.5050.53
210_I322_H0.5050.53
771_A774_V0.5050.53
497_A500_V0.5050.53
867_G898_G0.5040.53
819_V823_I0.5040.53
616_V620_L0.5040.53
104_L191_C0.5030.53
68_H134_V0.5030.53
212_V393_L0.5020.52
487_P493_M0.5020.52
815_V848_L0.5020.52
64_I613_P0.5020.52
479_H484_E0.5020.52
542_S580_M0.5020.52
112_K116_K0.5020.52
748_C752_L0.5020.52
286_G289_D0.5010.52
697_E799_A0.5010.52
66_I69_S0.5010.52
741_D746_R0.5000.52
118_T510_D0.5000.52
73_I629_V0.5000.52
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1ffyA 1 0.9659 100 0.141 Contact Map
1gaxA 1 0.8795 100 0.316 Contact Map
1ileA 1 0.8475 100 0.331 Contact Map
1wz2A 1 0.8955 100 0.355 Contact Map
1wkbA 1 0.7591 100 0.417 Contact Map
2v0cA 1 0.7239 100 0.452 Contact Map
4arcA 1 0.7377 100 0.469 Contact Map
3ziuA 1 0.6183 100 0.581 Contact Map
1rqgA 2 0.5693 100 0.676 Contact Map
4qreA 1 0.5352 100 0.68 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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