THRC - ECOLI - GREMLIN Contacts

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THRC - Threonine synthase

UniProt:	P00934	Sequences: MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEIDEMLKLDFVTRSAKILSAFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGPTLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGKISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLAQICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVNDTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDETTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEAILGETLDLPKELAERADLPLLSHNLPADFAALRKLMMNHQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11000
Length:	428 (418)
Sequences:	2567 (1588)
Seq/√Len:	77.7

ECOLI - THRC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
329_A	360_A	4.032	1.00
240_Q	267_K	3.947	1.00
68_P	120_H	3.549	1.00
341_R	344_K	3.522	1.00
332_D	335_T	3.359	1.00
78_A	116_Q	3.356	1.00
227_F	264_L	3.343	1.00
50_D	53_T	3.252	1.00
126_P	152_K	3.186	1.00
359_R	363_D	3.145	1.00
342_E	345_E	3.116	1.00
56_A	73_E	2.957	1.00
298_S	336_T	2.908	1.00
56_A	76_V	2.745	1.00
60_S	69_Q	2.718	1.00
183_D	414_P	2.661	1.00
84_A	109_F	2.607	1.00
159_R	183_D	2.577	1.00
280_P	328_Y	2.556	1.00
68_P	71_I	2.512	1.00
256_G	374_L	2.493	1.00
157_Y	179_T	2.475	1.00
320_I	324_K	2.413	1.00
350_S	358_Y	2.379	1.00
14_S	17_Q	2.331	1.00
39_S	42_E	2.320	1.00
88_N	94_G	2.303	1.00
164_P	167_E	2.288	1.00
125_K	207_G	2.251	1.00
337_Q	388_A	2.218	1.00
297_L	333_D	2.217	1.00
361_L	371_G	2.217	1.00
49_L	57_K	2.208	1.00
71_I	120_H	2.146	1.00
387_E	393_T	2.121	1.00
253_L	271_A	2.090	1.00
243_V	266_V	2.074	1.00
152_K	178_E	2.066	1.00
342_E	362_R	2.061	1.00
56_A	69_Q	2.050	1.00
242_V	267_K	2.045	1.00
12_Q	33_H	2.026	1.00
335_T	363_D	2.026	1.00
244_S	371_G	1.914	1.00
185_D	188_A	1.906	1.00
223_I	258_L	1.888	1.00
275_V	333_D	1.866	1.00
54_R	228_E	1.863	1.00
182_I	189_C	1.844	1.00
8_D	11_E	1.842	1.00
94_G	370_Y	1.834	1.00
192_L	420_L	1.826	1.00
180_V	413_L	1.819	1.00
113_F	117_M	1.816	1.00
49_L	54_R	1.803	1.00
241_L	372_L	1.790	1.00
129_I	145_F	1.783	1.00
2_K	33_H	1.781	1.00
343_L	350_S	1.779	1.00
354_A	375_G	1.778	1.00
315_L	319_K	1.776	1.00
244_S	270_I	1.749	1.00
287_Q	314_E	1.741	1.00
243_V	372_L	1.740	1.00
147_G	175_G	1.729	1.00
268_R	327_G	1.719	1.00
95_C	348_Y	1.716	1.00
228_E	232_Q	1.713	1.00
402_E	406_L	1.711	1.00
260_K	266_V	1.701	1.00
270_I	371_G	1.696	1.00
277_D	281_R	1.688	1.00
79_A	116_Q	1.674	1.00
280_P	284_H	1.672	1.00
67_I	71_I	1.666	1.00
329_A	363_D	1.666	1.00
72_L	76_V	1.646	1.00
297_L	337_Q	1.641	1.00
416_D	419_A	1.636	1.00
297_L	336_T	1.635	1.00
339_T	358_Y	1.633	1.00
54_R	231_A	1.609	1.00
275_V	294_Q	1.601	1.00
191_A	195_Q	1.594	1.00
199_D	421_R	1.593	1.00
56_A	60_S	1.592	1.00
44_D	237_T	1.592	1.00
86_V	372_L	1.586	1.00
94_G	233_L	1.585	1.00
243_V	256_G	1.580	1.00
316_F	319_K	1.577	0.99
173_L	406_L	1.570	0.99
74_E	78_A	1.569	0.99
267_K	369_E	1.562	0.99
67_I	120_H	1.559	0.99
350_S	354_A	1.559	0.99
277_D	330_A	1.554	0.99
184_G	188_A	1.553	0.99
243_V	374_L	1.538	0.99
253_L	269_F	1.538	0.99
21_Q	25_K	1.526	0.99
167_E	408_L	1.523	0.99
331_V	359_R	1.520	0.99
45_E	57_K	1.517	0.99
7_K	310_P	1.490	0.99
21_Q	30_F	1.485	0.99
143_H	146_Y	1.479	0.99
128_T	154_V	1.465	0.99
87_A	348_Y	1.464	0.99
47_L	234_P	1.460	0.99
48_K	235_Q	1.457	0.99
336_T	356_V	1.457	0.99
159_R	412_N	1.447	0.99
42_E	61_A	1.439	0.99
69_Q	73_E	1.426	0.99
42_E	46_M	1.421	0.99
92_D	368_G	1.418	0.99
322_Q	325_E	1.407	0.99
67_I	121_I	1.393	0.99
191_A	305_Q	1.384	0.99
183_D	412_N	1.383	0.99
88_N	91_S	1.379	0.99
97_E	100_H	1.363	0.99
10_N	30_F	1.351	0.98
398_K	402_E	1.351	0.98
16_A	121_I	1.343	0.98
59_L	113_F	1.333	0.98
317_R	321_W	1.325	0.98
96_L	229_A	1.317	0.98
229_A	372_L	1.313	0.98
339_T	362_R	1.298	0.98
333_D	336_T	1.294	0.98
52_V	77_R	1.289	0.98
339_T	359_R	1.286	0.98
86_V	233_L	1.279	0.98
337_Q	389_I	1.279	0.98
334_E	338_Q	1.277	0.98
57_K	61_A	1.273	0.98
343_L	358_Y	1.265	0.98
275_V	296_T	1.260	0.97
398_K	401_A	1.256	0.97
19_V	121_I	1.253	0.97
349_T	390_L	1.252	0.97
273_T	280_P	1.249	0.97
403_R	406_L	1.241	0.97
154_V	180_V	1.238	0.97
57_K	69_Q	1.226	0.97
15_F	63_I	1.221	0.97
335_T	359_R	1.215	0.97
116_Q	148_L	1.215	0.97
17_Q	21_Q	1.213	0.97
42_E	57_K	1.205	0.97
153_V	177_I	1.203	0.97
293_T	304_S	1.199	0.97
52_V	76_V	1.197	0.97
75_R	120_H	1.196	0.97
244_S	252_D	1.183	0.96
232_Q	235_Q	1.181	0.96
242_V	371_G	1.179	0.96
8_D	12_Q	1.176	0.96
93_V	373_F	1.164	0.96
5_N	26_N	1.154	0.96
254_T	258_L	1.153	0.96
230_V	234_P	1.150	0.96
159_R	167_E	1.147	0.96
242_V	369_E	1.138	0.95
122_A	127_V	1.138	0.95
47_L	237_T	1.137	0.95
182_I	413_L	1.135	0.95
419_A	422_K	1.132	0.95
33_H	37_E	1.132	0.95
89_V	95_C	1.132	0.95
196_A	421_R	1.127	0.95
36_P	262_L	1.126	0.95
352_P	385_S	1.123	0.95
201_E	204_V	1.123	0.95
46_M	49_L	1.122	0.95
252_D	374_L	1.120	0.95
357_A	373_F	1.117	0.95
9_H	12_Q	1.117	0.95
126_P	150_N	1.116	0.95
252_D	256_G	1.114	0.95
70_E	74_E	1.113	0.95
90_E	345_E	1.112	0.95
418_A	421_R	1.101	0.95
335_T	338_Q	1.090	0.94
25_K	30_F	1.089	0.94
73_E	77_R	1.078	0.94
164_P	168_K	1.076	0.94
111_G	144_A	1.072	0.94
40_L	44_D	1.067	0.94
290_P	305_Q	1.066	0.94
200_E	203_K	1.061	0.93
146_Y	174_G	1.061	0.93
186_F	190_Q	1.059	0.93
130_L	196_A	1.058	0.93
51_F	224_C	1.057	0.93
13_V	18_A	1.054	0.93
361_L	373_F	1.050	0.93
11_E	30_F	1.047	0.93
364_Q	369_E	1.043	0.93
129_I	209_N	1.041	0.93
281_R	291_K	1.040	0.93
4_Y	33_H	1.036	0.93
44_D	47_L	1.036	0.93
90_E	362_R	1.033	0.92
230_V	264_L	1.026	0.92
414_P	419_A	1.023	0.92
62_F	220_L	1.020	0.92
124_D	150_N	1.020	0.92
38_F	46_M	1.015	0.92
298_S	356_V	1.014	0.92
233_L	372_L	1.013	0.92
43_I	227_F	1.012	0.92
42_E	45_E	1.009	0.92
89_V	343_L	1.005	0.91
62_F	262_L	1.001	0.91
192_L	417_F	0.999	0.91
200_E	204_V	0.997	0.91
257_L	326_L	0.997	0.91
119_T	149_P	0.995	0.91
418_A	422_K	0.995	0.91
145_F	153_V	0.982	0.90
338_Q	341_R	0.981	0.90
402_E	405_D	0.979	0.90
13_V	30_F	0.976	0.90
275_V	332_D	0.976	0.90
3_L	62_F	0.968	0.90
154_V	178_E	0.967	0.90
331_V	356_V	0.965	0.90
55_S	224_C	0.955	0.89
273_T	328_Y	0.955	0.89
131_T	155_I	0.954	0.89
32_P	62_F	0.951	0.89
84_A	96_L	0.950	0.89
277_D	280_P	0.947	0.89
53_T	57_K	0.946	0.89
31_F	258_L	0.946	0.89
88_N	92_D	0.945	0.89
53_T	73_E	0.939	0.88
2_K	14_S	0.937	0.88
364_Q	367_P	0.936	0.88
102_P	112_R	0.934	0.88
35_L	62_F	0.933	0.88
415_A	419_A	0.928	0.88
84_A	228_E	0.923	0.87
95_C	350_S	0.920	0.87
234_P	237_T	0.918	0.87
54_R	58_I	0.913	0.87
35_L	258_L	0.910	0.87
56_A	77_R	0.906	0.86
417_F	421_R	0.904	0.86
57_K	60_S	0.904	0.86
90_E	93_V	0.901	0.86
56_A	72_L	0.900	0.86
37_E	261_S	0.899	0.86
338_Q	342_E	0.898	0.86
2_K	12_Q	0.898	0.86
327_G	364_Q	0.897	0.86
202_L	208_L	0.892	0.86
58_I	227_F	0.888	0.85
4_Y	12_Q	0.887	0.85
25_K	204_V	0.887	0.85
93_V	365_L	0.885	0.85
123_G	150_N	0.883	0.85
38_F	42_E	0.882	0.85
39_S	43_I	0.881	0.85
281_R	285_D	0.878	0.85
194_K	214_I	0.877	0.85
312_V	326_L	0.874	0.84
99_F	375_G	0.874	0.84
53_T	77_R	0.874	0.84
122_A	150_N	0.870	0.84
95_C	358_Y	0.869	0.84
71_I	74_E	0.864	0.84
148_L	151_V	0.862	0.84
234_P	238_R	0.862	0.84
134_S	194_K	0.862	0.84
160_G	167_E	0.860	0.83
32_P	36_P	0.859	0.83
220_L	223_I	0.856	0.83
171_C	408_L	0.849	0.83
286_G	320_I	0.849	0.83
190_Q	225_Y	0.847	0.82
267_K	366_N	0.845	0.82
196_A	208_L	0.844	0.82
366_N	369_E	0.831	0.81
297_L	385_S	0.831	0.81
46_M	54_R	0.830	0.81
74_E	120_H	0.829	0.81
229_A	243_V	0.829	0.81
358_Y	362_R	0.817	0.80
7_K	27_Q	0.816	0.80
53_T	318_R	0.815	0.80
334_E	337_Q	0.813	0.80
167_E	171_C	0.812	0.80
128_T	152_K	0.811	0.80
86_V	96_L	0.809	0.80
37_E	262_L	0.808	0.79
399_E	406_L	0.807	0.79
190_Q	194_K	0.804	0.79
254_T	257_L	0.802	0.79
243_V	252_D	0.802	0.79
3_L	216_I	0.800	0.79
244_S	373_F	0.799	0.79
186_F	249_N	0.799	0.79
133_T	138_G	0.798	0.79
321_W	324_K	0.797	0.78
241_L	266_V	0.797	0.78
167_E	220_L	0.796	0.78
241_L	267_K	0.795	0.78
27_Q	310_P	0.792	0.78
396_L	404_A	0.792	0.78
74_E	77_R	0.789	0.78
146_Y	175_G	0.789	0.78
195_Q	417_F	0.784	0.77
225_Y	249_N	0.781	0.77
401_A	404_A	0.780	0.77
339_T	343_L	0.778	0.77
119_T	148_L	0.777	0.77
161_K	295_A	0.772	0.76
272_A	360_A	0.771	0.76
8_D	13_V	0.770	0.76
249_N	307_N	0.766	0.76
278_T	281_R	0.765	0.76
159_R	181_A	0.763	0.75
242_V	367_P	0.763	0.75
256_G	269_F	0.753	0.74
52_V	94_G	0.751	0.74
199_D	202_L	0.750	0.74
281_R	289_S	0.748	0.74
94_G	372_L	0.741	0.73
11_E	25_K	0.741	0.73
112_R	216_I	0.740	0.73
157_Y	167_E	0.738	0.73
212_N	218_R	0.736	0.73
54_R	232_Q	0.735	0.73
358_Y	373_F	0.734	0.73
92_D	365_L	0.733	0.72
111_G	282_F	0.731	0.72
168_K	408_L	0.731	0.72
190_Q	307_N	0.727	0.72
67_I	72_L	0.723	0.71
272_A	340_M	0.723	0.71
59_L	63_I	0.723	0.71
244_S	361_L	0.722	0.71
185_D	293_T	0.721	0.71
89_V	346_L	0.720	0.71
104_L	400_L	0.719	0.71
411_H	418_A	0.719	0.71
194_K	225_Y	0.718	0.71
334_E	388_A	0.718	0.71
395_D	398_K	0.718	0.71
242_V	270_I	0.714	0.70
180_V	412_N	0.714	0.70
113_F	221_A	0.707	0.70
164_P	384_E	0.705	0.70
52_V	56_A	0.704	0.69
345_E	393_T	0.703	0.69
51_F	55_S	0.701	0.69
283_L	323_L	0.700	0.69
316_F	323_L	0.699	0.69
192_L	195_Q	0.698	0.69
391_G	394_L	0.697	0.69
116_Q	119_T	0.695	0.68
197_F	208_L	0.694	0.68
225_Y	307_N	0.694	0.68
153_V	179_T	0.690	0.68
186_F	225_Y	0.687	0.68
189_C	192_L	0.687	0.68
38_F	227_F	0.687	0.68
318_R	321_W	0.686	0.67
131_T	210_S	0.685	0.67
343_L	346_L	0.684	0.67
190_Q	249_N	0.684	0.67
186_F	194_K	0.681	0.67
97_E	348_Y	0.680	0.67
115_A	145_F	0.680	0.67
13_V	21_Q	0.680	0.67
397_P	406_L	0.679	0.67
244_S	272_A	0.679	0.67
164_P	404_A	0.677	0.66
131_T	216_I	0.677	0.66
5_N	24_G	0.675	0.66
34_D	37_E	0.675	0.66
6_L	310_P	0.674	0.66
42_E	58_I	0.674	0.66
139_A	300_A	0.673	0.66
331_V	336_T	0.673	0.66
134_S	307_N	0.673	0.66
83_P	399_E	0.673	0.66
181_A	410_S	0.672	0.66
349_T	386_V	0.672	0.66
46_M	57_K	0.671	0.66
216_I	219_L	0.671	0.66
73_E	76_V	0.671	0.66
247_S	252_D	0.667	0.65
153_V	157_Y	0.665	0.65
331_V	360_A	0.664	0.65
339_T	350_S	0.664	0.65
401_A	405_D	0.664	0.65
104_L	399_E	0.663	0.65
271_A	279_V	0.662	0.65
141_V	299_N	0.661	0.65
18_A	216_I	0.661	0.65
173_L	409_L	0.660	0.64
245_V	256_G	0.659	0.64
132_A	186_F	0.659	0.64
216_I	228_E	0.657	0.64
89_V	93_V	0.655	0.64
24_G	30_F	0.653	0.64
19_V	67_I	0.652	0.63
187_D	194_K	0.651	0.63
392_E	395_D	0.650	0.63
227_F	231_A	0.650	0.63
8_D	24_G	0.649	0.63
111_G	210_S	0.644	0.63
268_R	369_E	0.642	0.62
75_R	78_A	0.642	0.62
8_D	26_N	0.641	0.62
47_L	54_R	0.639	0.62
25_K	200_E	0.637	0.62
96_L	374_L	0.637	0.62
228_E	231_A	0.637	0.62
385_S	389_I	0.635	0.61
283_L	324_K	0.635	0.61
387_E	391_G	0.635	0.61
47_L	231_A	0.634	0.61
350_S	375_G	0.633	0.61
50_D	73_E	0.632	0.61
186_F	189_C	0.632	0.61
19_V	144_A	0.631	0.61
132_A	190_Q	0.629	0.61
144_A	162_I	0.628	0.61
324_K	342_E	0.627	0.60
122_A	216_I	0.627	0.60
45_E	48_K	0.627	0.60
417_F	420_L	0.626	0.60
74_E	205_A	0.625	0.60
76_V	79_A	0.622	0.60
278_T	304_S	0.620	0.60
273_T	306_P	0.619	0.60
93_V	362_R	0.619	0.60
84_A	229_A	0.618	0.59
59_L	220_L	0.616	0.59
242_V	361_L	0.614	0.59
223_I	300_A	0.614	0.59
244_S	360_A	0.614	0.59
118_L	127_V	0.614	0.59
38_F	61_A	0.613	0.59
339_T	342_E	0.613	0.59
75_R	79_A	0.612	0.59
146_Y	173_L	0.610	0.58
227_F	256_G	0.609	0.58
266_V	370_Y	0.609	0.58
245_V	269_F	0.609	0.58
353_H	377_A	0.608	0.58
187_D	190_Q	0.607	0.58
57_K	73_E	0.607	0.58
407_P	411_H	0.606	0.58
307_N	310_P	0.605	0.58
166_Q	382_F	0.604	0.58
253_L	326_L	0.603	0.58
194_K	307_N	0.603	0.58
250_F	273_T	0.602	0.57
23_L	198_D	0.602	0.57
411_H	415_A	0.602	0.57
137_T	213_S	0.599	0.57
105_A	134_S	0.599	0.57
143_H	149_P	0.598	0.57
165_L	383_K	0.597	0.57
338_Q	392_E	0.596	0.57
218_R	249_N	0.596	0.57
106_F	251_G	0.595	0.57
53_T	56_A	0.594	0.56
99_F	378_H	0.594	0.56
182_I	192_L	0.593	0.56
377_A	382_F	0.589	0.56
211_A	221_A	0.589	0.56
196_A	417_F	0.589	0.56
407_P	410_S	0.588	0.56
183_D	415_A	0.588	0.56
331_V	363_D	0.587	0.56
175_G	409_L	0.587	0.56
157_Y	171_C	0.586	0.55
122_A	151_V	0.586	0.55
30_F	52_V	0.586	0.55
262_L	265_P	0.586	0.55
315_L	320_I	0.585	0.55
343_L	362_R	0.585	0.55
6_L	31_F	0.584	0.55
285_D	289_S	0.584	0.55
269_F	328_Y	0.583	0.55
351_E	375_G	0.582	0.55
75_R	113_F	0.581	0.55
142_A	177_I	0.580	0.55
134_S	137_T	0.578	0.54
54_R	227_F	0.577	0.54
20_T	122_A	0.576	0.54
323_L	410_S	0.576	0.54
105_A	301_M	0.575	0.54
166_Q	353_H	0.573	0.54
134_S	190_Q	0.573	0.54
340_M	386_V	0.571	0.53
188_A	415_A	0.570	0.53
121_I	219_L	0.570	0.53
175_G	325_E	0.570	0.53
114_M	351_E	0.569	0.53
129_I	151_V	0.569	0.53
299_N	303_V	0.568	0.53
252_D	288_W	0.567	0.53
241_L	370_Y	0.566	0.53
57_K	347_G	0.566	0.53
194_K	249_N	0.565	0.53
194_K	301_M	0.563	0.52
137_T	187_D	0.563	0.52
321_W	325_E	0.562	0.52
59_L	224_C	0.561	0.52
242_V	364_Q	0.558	0.52
106_F	134_S	0.557	0.52
253_L	300_A	0.557	0.52
257_L	260_K	0.556	0.52
342_E	358_Y	0.556	0.52
139_A	143_H	0.556	0.52
113_F	189_C	0.554	0.51
163_S	225_Y	0.553	0.51
119_T	122_A	0.553	0.51
257_L	312_V	0.552	0.51
233_L	237_T	0.552	0.51
109_F	273_T	0.552	0.51
387_E	392_E	0.549	0.51
40_L	43_I	0.549	0.51
214_I	307_N	0.548	0.51
36_P	61_A	0.547	0.50
415_A	418_A	0.547	0.50
93_V	361_L	0.546	0.50
346_L	349_T	0.546	0.50
229_A	232_Q	0.545	0.50
139_A	179_T	0.545	0.50
3_L	109_F	0.544	0.50
3_L	25_K	0.543	0.50
275_V	297_L	0.543	0.50
314_E	317_R	0.543	0.50
363_D	421_R	0.540	0.50
173_L	407_P	0.540	0.50
201_E	205_A	0.539	0.49
214_I	225_Y	0.539	0.49
70_E	73_E	0.538	0.49
134_S	382_F	0.538	0.49
127_V	209_N	0.538	0.49
364_Q	371_G	0.537	0.49
168_K	172_T	0.536	0.49
124_D	406_L	0.536	0.49
37_E	123_G	0.535	0.49
144_A	148_L	0.535	0.49
147_G	174_G	0.534	0.49
299_N	306_P	0.534	0.49
250_F	272_A	0.534	0.49
106_F	187_D	0.533	0.49
122_A	389_I	0.533	0.49
111_G	145_F	0.532	0.49
4_Y	8_D	0.532	0.49
95_C	354_A	0.532	0.49
276_N	353_H	0.532	0.49
398_K	405_D	0.531	0.48
281_R	293_T	0.531	0.48
35_L	262_L	0.530	0.48
113_F	121_I	0.530	0.48
136_D	166_Q	0.528	0.48
75_R	116_Q	0.528	0.48
170_F	303_V	0.527	0.48
190_Q	193_V	0.527	0.48
212_N	249_N	0.527	0.48
132_A	225_Y	0.527	0.48
87_A	198_D	0.526	0.48
121_I	300_A	0.526	0.48
144_A	348_Y	0.526	0.48
99_F	349_T	0.525	0.48
67_I	117_M	0.525	0.48
278_T	306_P	0.525	0.48
114_M	217_S	0.522	0.47
304_S	390_L	0.522	0.47
134_S	225_Y	0.522	0.47
204_V	407_P	0.521	0.47
115_A	139_A	0.520	0.47
112_R	131_T	0.520	0.47
411_H	414_P	0.520	0.47
4_Y	25_K	0.520	0.47
214_I	226_Y	0.519	0.47
325_E	407_P	0.518	0.47
396_L	399_E	0.518	0.47
15_F	67_I	0.517	0.47
136_D	301_M	0.517	0.47
320_I	323_L	0.517	0.47
134_S	377_A	0.516	0.46
254_T	306_P	0.516	0.46
123_G	149_P	0.516	0.46
84_A	231_A	0.515	0.46
106_F	225_Y	0.514	0.46
204_V	207_G	0.514	0.46
270_I	364_Q	0.512	0.46
282_F	315_L	0.512	0.46
209_N	221_A	0.512	0.46
88_N	370_Y	0.511	0.46
413_L	419_A	0.511	0.46
74_E	116_Q	0.511	0.46
240_Q	370_Y	0.510	0.46
187_D	212_N	0.510	0.46
71_I	123_G	0.510	0.46
214_I	249_N	0.509	0.46
254_T	279_V	0.509	0.46
163_S	214_I	0.508	0.45
134_S	214_I	0.508	0.45
357_A	375_G	0.506	0.45
120_H	123_G	0.506	0.45
186_F	193_V	0.505	0.45
87_A	99_F	0.505	0.45
10_N	123_G	0.505	0.45
284_H	324_K	0.505	0.45
34_D	314_E	0.504	0.45
413_L	420_L	0.504	0.45
77_R	368_G	0.502	0.45
43_I	237_T	0.501	0.45
387_E	390_L	0.501	0.45
384_E	393_T	0.501	0.45
51_F	109_F	0.501	0.45
288_W	376_T	0.500	0.44

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1kl7A	1	0.9953	100	0.216	Contact Map
3v7nA	1	0.9603	100	0.232	Contact Map
1vb3A	1	1	100	0.235	Contact Map
4f4fA	1	0.9977	100	0.238	Contact Map
1e5xA	2	0.8808	100	0.472	Contact Map
4qysB	2	0.8364	100	0.541	Contact Map
3iauA	1	0.8154	100	0.551	Contact Map
2o2eA	2	0.6916	100	0.553	Contact Map
1x1qA	2	0.8201	100	0.556	Contact Map
4negA	2	0.7126	100	0.562	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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