TRPC - ECOLI - GREMLIN Contacts

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TRPC - Tryptophan biosynthesis protein TrpCF

UniProt:	P00909	Sequences: MMQTVLAKIVADKAIWVEARKQQQPLASFQNEVQPSTRHFYDALQGARTAFILECKKASPSKGVIRDDFDPARIAAIYKHYASAISVLTDEKYFQGSFNFLPIVSQIAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMGVLTEVSNEEEQERAIALGAKVVGINNRDLRDLSIDLNRTRELAPKLGHNVTVISESGINTYAQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVCGLTRGQDAKAAYDAGAIYGGLIFVATSPRCVNVEQAQEVMAAAPLQYVGVFRNHDIADVVDKAKVLSLAAVQLHGNEEQLYIDTLREALPAHVAIWKALSVGETLPAREFQHVDKYVLDNGQGGSGQRFDWSLLNGQSLGNVLLAGGLGADNCVEAAQTGCAGLDFNSAVESQPGIKDARLLASVFQTLRAY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11026
Length:	453 (443)
Sequences:	529 (344)
Seq/√Len:	16.3

ECOLI - TRPC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
143_D	146_Q	4.778	1.00
39_H	42_D	4.776	1.00
21_K	120_D	4.496	1.00
121_P	149_Q	4.394	1.00
269_A	300_V	4.379	1.00
144_D	173_R	3.842	1.00
320_V	342_Y	3.756	1.00
265_R	268_D	3.598	1.00
118_I	124_I	3.543	1.00
124_I	135_C	3.376	0.99
213_I	233_G	3.279	0.99
285_V	291_C	3.249	0.99
171_Q	206_L	3.230	0.99
85_I	108_A	3.113	0.99
236_I	253_V	3.087	0.99
182_V	206_L	3.018	0.98
431_V	446_V	2.870	0.98
310_G	329_L	2.857	0.98
315_H	319_D	2.854	0.98
104_V	112_I	2.784	0.97
392_W	417_A	2.775	0.97
409_L	427_F	2.757	0.97
263_L	280_G	2.745	0.97
414_C	427_F	2.511	0.95
314_N	337_N	2.510	0.95
4_T	194_I	2.449	0.94
172_E	205_K	2.418	0.94
175_I	182_V	2.416	0.94
240_L	246_L	2.403	0.94
12_D	16_W	2.381	0.94
404_L	424_G	2.361	0.93
427_F	446_V	2.312	0.92
427_F	450_L	2.311	0.92
200_R	226_E	2.287	0.92
124_I	158_E	2.259	0.92
221_Y	225_R	2.229	0.91
433_S	439_D	2.204	0.90
340_Q	344_D	2.202	0.90
64_V	95_Q	2.173	0.90
160_G	181_V	2.162	0.90
40_F	181_V	2.120	0.89
378_V	404_L	2.096	0.88
70_D	73_R	2.092	0.88
445_S	449_T	2.042	0.87
12_D	92_K	2.040	0.87
265_R	437_I	2.036	0.87
125_Y	153_V	2.031	0.86
280_G	306_L	2.030	0.86
168_E	205_K	2.009	0.86
300_V	303_A	1.926	0.83
431_V	443_L	1.907	0.83
169_E	292_V	1.902	0.82
37_T	105_S	1.894	0.82
17_V	119_I	1.876	0.82
186_N	199_T	1.872	0.81
171_Q	203_A	1.871	0.81
206_L	210_V	1.870	0.81
4_T	190_R	1.853	0.81
258_N	278_I	1.841	0.80
347_R	356_I	1.823	0.80
12_D	93_Y	1.821	0.79
29_F	125_Y	1.816	0.79
128_R	159_M	1.813	0.79
300_V	304_A	1.813	0.79
196_L	212_V	1.808	0.79
293_N	296_Q	1.803	0.79
410_G	430_A	1.796	0.79
339_E	342_Y	1.795	0.78
181_V	211_T	1.786	0.78
14_A	146_Q	1.783	0.78
171_Q	205_K	1.774	0.78
71_P	107_I	1.769	0.77
4_T	118_I	1.745	0.76
13_K	90_D	1.738	0.76
269_A	308_Y	1.732	0.76
320_V	332_V	1.718	0.75
224_V	236_I	1.677	0.73
58_A	62_K	1.663	0.73
409_L	425_L	1.633	0.71
13_K	91_E	1.633	0.71
20_R	24_Q	1.627	0.71
338_E	358_K	1.625	0.71
427_F	431_V	1.623	0.71
300_V	308_Y	1.611	0.70
175_I	210_V	1.605	0.70
75_A	84_A	1.583	0.69
57_K	100_F	1.569	0.68
362_V	394_L	1.559	0.68
72_A	107_I	1.531	0.66
7_A	33_V	1.515	0.65
204_P	233_G	1.499	0.65
151_A	161_V	1.498	0.65
166_S	190_R	1.487	0.64
16_W	92_K	1.466	0.63
178_G	206_L	1.449	0.62
301_M	308_Y	1.447	0.62
418_A	450_L	1.441	0.61
317_I	321_V	1.440	0.61
66_R	69_F	1.392	0.59
146_Q	149_Q	1.385	0.58
294_V	323_K	1.380	0.58
11_A	14_A	1.376	0.58
26_L	29_F	1.375	0.58
411_A	414_C	1.373	0.58
167_N	188_D	1.372	0.58
207_G	210_V	1.369	0.57
282_L	288_S	1.361	0.57
414_C	418_A	1.357	0.57
265_R	300_V	1.351	0.56
47_A	158_E	1.347	0.56
409_L	446_V	1.346	0.56
40_F	160_G	1.341	0.56
314_N	338_E	1.340	0.56
71_P	75_A	1.338	0.56
271_A	275_A	1.329	0.55
272_A	277_A	1.326	0.55
146_Q	419_Q	1.326	0.55
320_V	324_A	1.319	0.54
285_V	313_R	1.289	0.53
40_F	157_L	1.289	0.53
245_D	328_S	1.285	0.52
147_Y	163_T	1.285	0.52
40_F	84_A	1.284	0.52
197_N	200_R	1.281	0.52
199_T	213_I	1.275	0.52
260_V	292_V	1.275	0.52
41_Y	181_V	1.273	0.52
282_L	297_A	1.270	0.52
57_K	69_F	1.270	0.52
52_I	213_I	1.269	0.52
25_P	29_F	1.269	0.52
26_L	125_Y	1.266	0.51
142_L	165_V	1.259	0.51
260_V	391_D	1.257	0.51
19_A	23_Q	1.245	0.50
263_L	438_K	1.244	0.50
145_D	148_R	1.241	0.50
72_A	103_I	1.239	0.50
297_A	334_L	1.231	0.49
125_Y	157_L	1.221	0.49
190_R	240_L	1.218	0.49
312_F	329_L	1.216	0.48
121_P	146_Q	1.214	0.48
214_S	227_L	1.209	0.48
286_A	369_R	1.206	0.48
239_A	381_N	1.198	0.47
70_D	435_P	1.198	0.47
196_L	224_V	1.188	0.47
74_I	241_M	1.186	0.47
412_D	445_S	1.175	0.46
347_R	375_D	1.174	0.46
6_L	9_I	1.169	0.46
271_A	443_L	1.154	0.45
285_V	315_H	1.154	0.45
17_V	450_L	1.146	0.44
246_L	250_V	1.145	0.44
16_W	84_A	1.137	0.44
298_Q	326_V	1.136	0.44
167_N	198_R	1.126	0.43
274_D	416_E	1.124	0.43
312_F	334_L	1.121	0.43
270_K	303_A	1.119	0.43
270_K	299_E	1.118	0.43
221_Y	439_D	1.116	0.43
155_H	180_K	1.112	0.42
151_A	155_H	1.107	0.42
379_L	403_V	1.107	0.42
381_N	414_C	1.099	0.42
30_Q	125_Y	1.096	0.41
178_G	182_V	1.088	0.41
5_V	169_E	1.084	0.41
286_A	315_H	1.076	0.40
286_A	319_D	1.072	0.40
62_K	89_T	1.071	0.40
288_S	438_K	1.068	0.40
414_C	450_L	1.067	0.40
247_H	250_V	1.062	0.40
17_V	231_A	1.058	0.39
362_V	377_Y	1.058	0.39
39_H	155_H	1.058	0.39
81_Y	147_Y	1.058	0.39
316_D	320_V	1.057	0.39
284_F	288_S	1.056	0.39
425_L	428_N	1.056	0.39
152_A	156_S	1.054	0.39
396_N	399_S	1.050	0.39
116_D	438_K	1.046	0.39
228_S	279_Y	1.045	0.39
75_A	113_L	1.044	0.39
283_I	311_V	1.043	0.38
169_E	172_E	1.040	0.38
175_I	206_L	1.033	0.38
101_L	254_L	1.031	0.38
321_V	342_Y	1.024	0.37
310_G	338_E	1.021	0.37
182_V	210_V	1.020	0.37
4_T	439_D	1.018	0.37
171_Q	199_T	1.018	0.37
75_A	181_V	1.018	0.37
81_Y	138_M	1.015	0.37
91_E	214_S	1.012	0.37
135_C	283_I	1.011	0.37
49_T	65_I	1.009	0.37
248_A	278_I	1.008	0.37
50_A	285_V	1.002	0.36
46_G	232_N	1.001	0.36
169_E	332_V	0.999	0.36
138_M	192_L	0.999	0.36
269_A	303_A	0.993	0.36
122_Y	241_M	0.993	0.36
52_I	215_E	0.988	0.35
197_N	226_E	0.986	0.35
138_M	147_Y	0.985	0.35
332_V	346_L	0.985	0.35
263_L	306_L	0.984	0.35
250_V	253_V	0.983	0.35
182_V	254_L	0.982	0.35
172_E	176_A	0.978	0.35
40_F	159_M	0.974	0.35
84_A	198_R	0.974	0.35
10_V	119_I	0.972	0.35
418_A	427_F	0.969	0.34
425_L	446_V	0.968	0.34
97_S	129_Y	0.965	0.34
316_D	319_D	0.958	0.34
182_V	253_V	0.957	0.34
340_Q	411_A	0.955	0.34
199_T	231_A	0.954	0.34
165_V	171_Q	0.952	0.34
366_L	395_L	0.951	0.34
294_V	298_Q	0.947	0.33
284_F	392_W	0.945	0.33
317_I	320_V	0.941	0.33
194_I	242_A	0.937	0.33
367_P	395_L	0.935	0.33
252_R	257_E	0.935	0.33
112_I	239_A	0.931	0.32
193_S	359_A	0.927	0.32
270_K	273_Y	0.926	0.32
184_I	358_K	0.926	0.32
12_D	29_F	0.925	0.32
141_V	177_L	0.921	0.32
50_A	160_G	0.921	0.32
261_C	407_G	0.915	0.32
173_R	280_G	0.910	0.31
307_Q	330_A	0.906	0.31
378_V	398_Q	0.905	0.31
314_N	334_L	0.905	0.31
27_A	292_V	0.905	0.31
184_I	200_R	0.904	0.31
5_V	206_L	0.903	0.31
51_F	255_L	0.902	0.31
273_Y	305_P	0.900	0.31
321_V	346_L	0.891	0.30
16_W	160_G	0.889	0.30
3_Q	194_I	0.888	0.30
411_A	431_V	0.887	0.30
81_Y	163_T	0.886	0.30
188_D	242_A	0.886	0.30
85_I	212_V	0.886	0.30
272_A	276_G	0.885	0.30
11_A	106_Q	0.882	0.30
90_D	214_S	0.882	0.30
147_Y	238_S	0.880	0.30
46_G	411_A	0.880	0.30
412_D	449_T	0.879	0.30
16_W	90_D	0.876	0.30
15_I	92_K	0.869	0.29
138_M	238_S	0.868	0.29
99_N	158_E	0.867	0.29
428_N	446_V	0.865	0.29
297_A	312_F	0.860	0.29
13_K	16_W	0.860	0.29
27_A	445_S	0.860	0.29
153_V	161_V	0.857	0.29
7_A	340_Q	0.857	0.29
49_T	159_M	0.857	0.29
186_N	241_M	0.856	0.29
134_A	215_E	0.856	0.29
121_P	165_V	0.855	0.29
12_D	15_I	0.852	0.29
268_D	437_I	0.852	0.29
3_Q	190_R	0.851	0.29
175_I	379_L	0.851	0.29
319_D	323_K	0.850	0.28
236_I	250_V	0.846	0.28
224_V	320_V	0.844	0.28
16_W	181_V	0.844	0.28
291_C	315_H	0.844	0.28
31_N	211_T	0.842	0.28
160_G	236_I	0.841	0.28
312_F	338_E	0.837	0.28
238_S	428_N	0.837	0.28
186_N	214_S	0.836	0.28
121_P	161_V	0.836	0.28
114_C	127_A	0.834	0.28
163_T	428_N	0.832	0.28
11_A	124_I	0.831	0.28
138_M	234_F	0.830	0.28
273_Y	304_A	0.829	0.27
138_M	163_T	0.827	0.27
33_V	129_Y	0.827	0.27
362_V	379_L	0.825	0.27
382_G	386_S	0.823	0.27
71_P	105_S	0.822	0.27
223_Q	226_E	0.821	0.27
49_T	245_D	0.820	0.27
361_S	383_Q	0.819	0.27
360_L	377_Y	0.819	0.27
150_L	240_L	0.819	0.27
191_D	277_A	0.817	0.27
380_D	387_G	0.815	0.27
360_L	381_N	0.814	0.27
409_L	418_A	0.813	0.27
131_Q	250_V	0.812	0.27
446_V	450_L	0.812	0.27
177_L	202_L	0.809	0.27
17_V	369_R	0.808	0.27
188_D	265_R	0.803	0.26
41_Y	180_K	0.797	0.26
334_L	338_E	0.797	0.26
302_A	318_A	0.795	0.26
104_V	143_D	0.790	0.26
240_L	254_L	0.790	0.26
318_A	345_T	0.788	0.26
153_V	156_S	0.787	0.26
105_S	381_N	0.785	0.25
135_C	154_A	0.782	0.25
7_A	83_S	0.775	0.25
167_N	273_Y	0.773	0.25
20_R	29_F	0.773	0.25
291_C	316_D	0.773	0.25
139_L	234_F	0.772	0.25
194_I	220_T	0.771	0.25
232_N	331_A	0.769	0.25
128_R	133_D	0.766	0.25
39_H	127_A	0.766	0.25
155_H	160_G	0.765	0.25
127_A	181_V	0.764	0.25
340_Q	374_V	0.764	0.25
79_K	105_S	0.764	0.25
186_N	338_E	0.763	0.25
81_Y	247_H	0.761	0.24
25_P	122_Y	0.761	0.24
73_R	386_S	0.760	0.24
331_A	357_W	0.757	0.24
346_L	412_D	0.756	0.24
312_F	320_V	0.756	0.24
16_W	131_Q	0.754	0.24
305_P	309_V	0.754	0.24
116_D	392_W	0.752	0.24
49_T	224_V	0.752	0.24
288_S	359_A	0.750	0.24
293_N	315_H	0.749	0.24
55_C	163_T	0.748	0.24
139_L	147_Y	0.747	0.24
243_H	253_V	0.745	0.24
97_S	112_I	0.745	0.24
363_G	410_G	0.745	0.24
182_V	205_K	0.745	0.24
260_V	447_F	0.743	0.24
147_Y	428_N	0.742	0.24
114_C	126_L	0.740	0.24
174_A	312_F	0.740	0.24
341_L	419_Q	0.740	0.24
172_E	245_D	0.735	0.23
45_Q	232_N	0.732	0.23
278_I	405_L	0.731	0.23
247_H	251_R	0.730	0.23
58_A	309_V	0.730	0.23
118_I	231_A	0.729	0.23
446_V	449_T	0.729	0.23
225_R	255_L	0.727	0.23
199_T	227_L	0.725	0.23
236_I	386_S	0.723	0.23
180_K	224_V	0.723	0.23
163_T	238_S	0.722	0.23
155_H	159_M	0.721	0.23
233_G	414_C	0.720	0.23
244_D	302_A	0.719	0.23
404_L	423_A	0.715	0.22
184_I	199_T	0.713	0.22
391_D	431_V	0.712	0.22
135_C	161_V	0.709	0.22
243_H	252_R	0.709	0.22
148_R	344_D	0.709	0.22
287_T	291_C	0.708	0.22
300_V	445_S	0.707	0.22
145_D	266_G	0.707	0.22
261_C	408_G	0.707	0.22
264_T	356_I	0.707	0.22
414_C	449_T	0.701	0.22
71_P	275_A	0.701	0.22
229_H	448_Q	0.700	0.22
71_P	382_G	0.697	0.22
340_Q	372_Q	0.696	0.22
118_I	253_V	0.695	0.22
45_Q	299_E	0.695	0.22
186_N	312_F	0.694	0.22
114_C	258_N	0.694	0.22
42_D	314_N	0.692	0.22
322_D	388_Q	0.691	0.22
114_C	138_M	0.688	0.21
178_G	425_L	0.686	0.21
163_T	184_I	0.685	0.21
204_P	341_L	0.685	0.21
219_N	239_A	0.683	0.21
144_D	176_A	0.682	0.21
13_K	57_K	0.682	0.21
5_V	278_I	0.680	0.21
170_E	253_V	0.680	0.21
184_I	212_V	0.679	0.21
265_R	299_E	0.678	0.21
80_H	439_D	0.678	0.21
362_V	390_F	0.677	0.21
207_G	429_S	0.677	0.21
138_M	256_G	0.677	0.21
18_E	119_I	0.676	0.21
84_A	181_V	0.675	0.21
122_Y	126_L	0.675	0.21
199_T	241_M	0.675	0.21
73_R	121_P	0.674	0.21
105_S	133_D	0.673	0.21
207_G	271_A	0.672	0.21
287_T	313_R	0.672	0.21
263_L	377_Y	0.672	0.21
176_A	368_A	0.670	0.21
152_A	415_V	0.670	0.21
145_D	195_D	0.670	0.21
123_Q	150_L	0.669	0.21
214_S	231_A	0.668	0.21
362_V	403_V	0.668	0.21
381_N	395_L	0.667	0.21
64_V	67_D	0.665	0.21
113_L	132_A	0.665	0.21
118_I	123_Q	0.664	0.20
186_N	231_A	0.664	0.20
324_A	334_L	0.663	0.20
89_T	336_G	0.663	0.20
192_L	238_S	0.663	0.20
286_A	291_C	0.663	0.20
425_L	450_L	0.662	0.20
227_L	240_L	0.660	0.20
295_E	326_V	0.658	0.20
409_L	430_A	0.657	0.20
90_D	354_V	0.656	0.20
58_A	95_Q	0.655	0.20
65_I	384_G	0.654	0.20
198_R	201_E	0.653	0.20
188_D	381_N	0.653	0.20
291_C	342_Y	0.653	0.20
261_C	406_A	0.652	0.20
55_C	192_L	0.648	0.20
126_L	163_T	0.647	0.20
282_L	287_T	0.645	0.20
201_E	332_V	0.645	0.20
196_L	375_D	0.644	0.20
175_I	208_H	0.643	0.20
220_T	225_R	0.643	0.20
79_K	159_M	0.643	0.20
52_I	84_A	0.643	0.20
171_Q	202_L	0.641	0.20
292_V	318_A	0.638	0.20
163_T	192_L	0.635	0.19
111_P	312_F	0.635	0.19
3_Q	409_L	0.634	0.19
79_K	188_D	0.634	0.19
89_T	329_L	0.633	0.19
241_M	312_F	0.633	0.19
378_V	415_V	0.633	0.19
116_D	140_S	0.632	0.19
55_C	69_F	0.631	0.19
355_A	396_N	0.629	0.19
128_R	199_T	0.629	0.19
182_V	449_T	0.629	0.19
47_A	443_L	0.628	0.19
276_G	306_L	0.628	0.19
100_F	230_F	0.627	0.19
204_P	207_G	0.626	0.19
290_R	407_G	0.624	0.19
265_R	377_Y	0.624	0.19
395_L	400_L	0.623	0.19
443_L	450_L	0.623	0.19
414_C	425_L	0.623	0.19
264_T	435_P	0.621	0.19
10_V	141_V	0.620	0.19
382_G	429_S	0.620	0.19
293_N	439_D	0.620	0.19
138_M	278_I	0.620	0.19
158_E	427_F	0.620	0.19
165_V	443_L	0.620	0.19
201_E	206_L	0.619	0.19
105_S	188_D	0.615	0.19
68_D	222_A	0.614	0.19
3_Q	361_S	0.613	0.19
80_H	293_N	0.613	0.19
165_V	360_L	0.612	0.19
145_D	169_E	0.611	0.19
209_N	251_R	0.611	0.19
139_L	163_T	0.611	0.19
277_A	447_F	0.610	0.18
440_A	445_S	0.609	0.18
322_D	326_V	0.609	0.18
69_F	100_F	0.608	0.18
385_G	407_G	0.607	0.18
44_L	211_T	0.605	0.18
428_N	450_L	0.603	0.18
83_S	100_F	0.603	0.18
224_V	427_F	0.602	0.18
222_A	396_N	0.602	0.18
55_C	138_M	0.601	0.18
62_K	95_Q	0.601	0.18
134_A	154_A	0.600	0.18
188_D	322_D	0.598	0.18
434_Q	437_I	0.598	0.18
221_Y	246_L	0.598	0.18
116_D	288_S	0.596	0.18
155_H	161_V	0.595	0.18
84_A	159_M	0.594	0.18
155_H	443_L	0.594	0.18
114_C	306_L	0.594	0.18
79_K	292_V	0.593	0.18
99_N	156_S	0.593	0.18
124_I	153_V	0.591	0.18
21_K	404_L	0.591	0.18
14_A	18_E	0.591	0.18
365_T	412_D	0.589	0.18
415_V	427_F	0.588	0.18
198_R	276_G	0.588	0.18
53_L	138_M	0.587	0.18
30_Q	45_Q	0.587	0.18
290_R	408_G	0.586	0.18
124_I	295_E	0.585	0.18
21_K	122_Y	0.584	0.18
332_V	410_G	0.583	0.18
270_K	302_A	0.583	0.18
54_E	60_P	0.582	0.18
56_K	60_P	0.582	0.18
84_A	194_I	0.581	0.17
17_V	129_Y	0.580	0.17
195_D	269_A	0.580	0.17
312_F	336_G	0.580	0.17
181_V	313_R	0.579	0.17
16_W	98_F	0.578	0.17
17_V	188_D	0.578	0.17
297_A	329_L	0.578	0.17
167_N	205_K	0.577	0.17
147_Y	234_F	0.575	0.17
364_E	367_P	0.575	0.17
49_T	255_L	0.574	0.17
364_E	449_T	0.574	0.17
102_P	106_Q	0.573	0.17
196_L	424_G	0.570	0.17
148_R	152_A	0.570	0.17
24_Q	210_V	0.570	0.17
298_Q	302_A	0.570	0.17
201_E	443_L	0.569	0.17
233_G	289_P	0.569	0.17
326_V	419_Q	0.568	0.17
263_L	282_L	0.567	0.17
112_I	359_A	0.567	0.17
385_G	408_G	0.567	0.17
393_S	444_A	0.565	0.17
214_S	356_I	0.563	0.17
122_Y	314_N	0.562	0.17
76_A	443_L	0.561	0.17
140_S	395_L	0.560	0.17
270_K	274_D	0.559	0.17
83_S	108_A	0.558	0.17
158_E	366_L	0.557	0.17
147_Y	161_V	0.557	0.17
376_K	404_L	0.557	0.17
29_F	153_V	0.556	0.17
75_A	132_A	0.555	0.17
362_V	395_L	0.554	0.17
139_L	177_L	0.554	0.17
139_L	192_L	0.554	0.17
142_L	167_N	0.553	0.17
324_A	332_V	0.553	0.17
192_L	242_A	0.551	0.17
300_V	360_L	0.550	0.16
99_N	220_T	0.549	0.16
101_L	223_Q	0.549	0.16
66_R	192_L	0.548	0.16
111_P	186_N	0.548	0.16
126_L	129_Y	0.547	0.16
46_G	49_T	0.547	0.16
140_S	282_L	0.543	0.16
168_E	199_T	0.543	0.16
251_R	260_V	0.542	0.16
32_E	35_P	0.542	0.16
318_A	405_L	0.542	0.16
81_Y	192_L	0.542	0.16
138_M	161_V	0.541	0.16
267_Q	273_Y	0.541	0.16
97_S	206_L	0.541	0.16
85_I	275_A	0.541	0.16
447_F	450_L	0.540	0.16
212_V	303_A	0.539	0.16
93_Y	215_E	0.539	0.16
344_D	445_S	0.539	0.16
11_A	101_L	0.539	0.16
72_A	105_S	0.538	0.16
85_I	379_L	0.538	0.16
261_C	385_G	0.537	0.16
323_K	354_V	0.537	0.16
154_A	392_W	0.535	0.16
155_H	386_S	0.534	0.16
406_A	430_A	0.534	0.16
178_G	274_D	0.534	0.16
200_R	230_F	0.533	0.16
13_K	110_Q	0.533	0.16
92_K	241_M	0.533	0.16
117_F	311_V	0.532	0.16
186_N	297_A	0.531	0.16
100_F	253_V	0.530	0.16
234_F	428_N	0.530	0.16
45_Q	152_A	0.530	0.16
90_D	166_S	0.529	0.16
53_L	57_K	0.527	0.16
296_Q	332_V	0.527	0.16
278_I	318_A	0.527	0.16
29_F	130_Y	0.527	0.16
135_C	220_T	0.527	0.16
221_Y	257_E	0.527	0.16
52_I	55_C	0.526	0.16
7_A	11_A	0.525	0.16
143_D	149_Q	0.524	0.16
336_G	358_K	0.524	0.16
112_I	198_R	0.520	0.16
13_K	93_Y	0.520	0.16
244_D	318_A	0.519	0.15
5_V	67_D	0.519	0.15
7_A	14_A	0.518	0.15
182_V	209_N	0.518	0.15
264_T	268_D	0.518	0.15
175_I	220_T	0.517	0.15
114_C	163_T	0.515	0.15
318_A	323_K	0.515	0.15
250_V	254_L	0.514	0.15
97_S	100_F	0.514	0.15
131_Q	160_G	0.512	0.15
84_A	236_I	0.512	0.15
416_E	420_T	0.511	0.15
42_D	343_I	0.511	0.15
16_W	20_R	0.511	0.15
206_L	209_N	0.508	0.15
192_L	278_I	0.507	0.15
93_Y	105_S	0.505	0.15
52_I	447_F	0.505	0.15
4_T	119_I	0.505	0.15
46_G	293_N	0.504	0.15
153_V	157_L	0.504	0.15
261_C	290_R	0.503	0.15
324_A	329_L	0.503	0.15
252_R	378_V	0.502	0.15
163_T	234_F	0.502	0.15
107_I	450_L	0.502	0.15
72_A	172_E	0.501	0.15
29_F	122_Y	0.501	0.15
279_Y	400_L	0.501	0.15
280_G	428_N	0.501	0.15
258_N	424_G	0.500	0.15
13_K	214_S	0.500	0.15

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1piiA	1	0.9978	100	0.298	Contact Map
3tsmA	2	0.5585	100	0.665	Contact Map
1i4nA	1	0.5497	100	0.672	Contact Map
1v5xA	2	0.426	100	0.676	Contact Map
4aajA	1	0.404	100	0.69	Contact Map
3qjaA	1	0.5497	100	0.696	Contact Map
1vc4A	2	0.5519	100	0.697	Contact Map
4a29A	1	0.5342	100	0.7	Contact Map
1nsjA	2	0.4305	100	0.721	Contact Map
4wuiA	1	0.426	100	0.741	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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