GREMLIN Database
RPOD - RNA polymerase sigma factor RpoD
UniProt: P00579 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10896
Length: 613 (599)
Sequences: 835 (379)
Seq/√Len: 15.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
309_N312_S10.3511.00
149_D225_R6.0011.00
279_R350_E5.8951.00
73_D76_A4.5051.00
470_M474_M4.3071.00
224_L259_F4.1721.00
320_I327_S3.9471.00
230_V247_E3.7771.00
466_I487_M3.6851.00
250_L254_E3.5570.99
476_R482_E3.1400.99
234_T238_K2.9930.98
322_M327_S2.9850.98
149_D153_A2.8790.97
463_L487_M2.8780.97
334_S338_H2.8750.97
76_A80_A2.8130.97
176_P179_T2.7670.97
10_K51_M2.7580.97
283_Q340_A2.6160.95
230_V243_A2.5890.95
435_I439_I2.5140.94
73_D77_A2.4920.94
319_A330_L2.4880.94
80_A84_L2.4520.94
317_N334_S2.4150.93
473_E486_R2.4050.93
122_R378_E2.3950.93
210_N213_D2.3900.93
227_Q248_E2.3820.93
109_E115_G2.3230.92
484_A489_M2.3220.92
414_K558_V2.2600.90
74_E77_A2.2540.90
211_S215_E2.2470.90
150_R155_E2.2330.90
487_M494_I2.2250.90
379_M388_I2.1910.89
192_D196_E2.1850.89
88_E91_I2.1750.89
84_L87_V2.1550.88
13_V79_A2.1470.88
580_F587_I2.1390.88
299_K542_A2.1130.87
134_V261_L2.0900.86
126_G368_G2.0840.86
511_I547_V2.0770.86
12_L16_G2.0730.86
466_I494_I2.0010.84
125_D371_K1.9920.84
420_E558_V1.9920.84
195_D198_E1.9280.81
388_I513_D1.9240.81
476_R497_V1.9100.81
227_Q251_K1.8930.80
580_F593_K1.8830.80
230_V233_D1.8780.80
290_L333_V1.8490.79
479_T482_E1.8390.78
218_R231_T1.8280.78
208_D212_I1.8270.78
595_L610_F1.8230.78
239_G242_H1.8220.78
452_I596_R1.8170.77
108_V595_L1.7940.76
367_I370_A1.7620.75
505_I509_T1.7600.75
476_R481_E1.7580.75
517_S592_A1.7440.74
177_T181_V1.7230.73
333_V337_V1.7190.73
314_T317_N1.7190.73
164_G167_D1.7180.73
10_K604_S1.7160.73
77_A83_V1.7160.73
106_G435_I1.7100.73
188_E192_D1.7040.73
129_Q367_I1.6990.72
48_I51_M1.6960.72
567_M579_Q1.6820.72
269_L611_L1.6770.71
32_P515_E1.6640.71
16_G26_E1.6580.70
81_A380_V1.6420.70
13_V51_M1.6410.70
600_H603_R1.6400.70
88_E92_G1.6360.69
592_A595_L1.6320.69
90_E169_N1.6310.69
40_Q43_D1.6210.69
109_E442_S1.5940.67
248_E352_G1.5940.67
342_Q345_Q1.5800.67
288_M299_K1.5740.66
95_T102_M1.5670.66
85_S515_E1.5640.66
37_D507_M1.5510.65
388_I442_S1.5500.65
238_K244_T1.5410.65
134_V141_I1.5210.63
14_T48_I1.5200.63
181_V193_D1.5120.63
507_M605_E1.5110.63
395_T509_T1.5020.62
149_D152_E1.4980.62
144_L210_N1.4950.62
256_F533_D1.4850.62
301_N319_A1.4830.61
102_M491_E1.4820.61
353_L494_I1.4810.61
517_S522_F1.4710.61
505_I518_H1.4660.61
587_I593_K1.4640.60
213_D218_R1.4620.60
574_E583_T1.4620.60
595_L599_R1.4580.60
312_S318_A1.4580.60
117_I267_D1.4570.60
27_V514_D1.4570.60
263_P266_F1.4550.60
134_V260_R1.4530.60
40_Q48_I1.4500.60
545_H566_D1.4470.59
289_K293_E1.4460.59
193_D199_E1.4450.59
442_S567_M1.4350.59
191_D194_E1.4340.59
142_T146_E1.4280.58
341_L488_L1.4270.58
227_Q231_T1.4260.58
35_I38_S1.4250.58
134_V351_T1.4230.58
274_R369_E1.4170.58
474_M486_R1.4160.58
454_V576_V1.4160.58
43_D608_R1.4030.57
131_Q266_F1.3990.57
471_L513_D1.3950.57
395_T518_H1.3950.57
128_N141_I1.3820.56
102_M507_M1.3770.56
436_R458_E1.3770.56
219_E251_K1.3690.55
344_L556_A1.3650.55
311_T348_E1.3630.55
52_G94_T1.3580.55
366_S374_R1.3530.54
233_D247_E1.3510.54
342_Q346_Q1.3500.54
15_R347_I1.3480.54
467_S569_T1.3460.54
64_D86_S1.3440.54
77_A81_A1.3420.54
16_G29_D1.3410.54
190_L194_E1.3380.53
470_M476_R1.3370.53
24_Y505_I1.3260.53
165_F371_K1.3260.53
148_Y213_D1.3170.52
100_M561_M1.3150.52
274_R362_N1.3130.52
281_R306_F1.3130.52
260_R534_S1.3060.52
583_T593_K1.3040.51
290_L337_V1.3000.51
438_A447_A1.2990.51
135_A147_Q1.2990.51
320_I338_H1.2980.51
368_G522_F1.2970.51
301_N356_E1.2970.51
295_C333_V1.2970.51
174_L177_T1.2920.51
447_A457_I1.2910.51
460_I501_A1.2900.51
257_K530_L1.2880.51
179_T254_E1.2810.50
226_A237_A1.2780.50
242_H245_A1.2720.50
284_E359_K1.2710.50
422_R579_Q1.2660.49
520_G563_F1.2620.49
511_I518_H1.2610.49
359_K533_D1.2590.49
140_A144_L1.2580.49
489_M552_T1.2470.48
136_E277_M1.2470.48
316_F327_S1.2460.48
388_I568_N1.2440.48
535_A569_T1.2440.48
464_N494_I1.2370.48
420_E516_D1.2360.48
118_D478_P1.2350.48
496_K600_H1.2330.47
144_L213_D1.2310.47
561_M567_M1.2300.47
310_E480_P1.2300.47
459_T499_K1.2260.47
119_I602_S1.2220.47
60_P95_T1.2210.47
442_S579_Q1.2200.47
77_A80_A1.2190.47
95_T491_E1.2170.46
148_Y221_F1.2150.46
167_D353_L1.2110.46
457_I461_N1.2100.46
227_Q252_L1.2050.46
13_V260_R1.1980.45
222_A226_A1.1940.45
505_I511_I1.1870.45
63_D160_D1.1870.45
144_L347_I1.1850.45
43_D57_E1.1840.45
16_G374_R1.1800.44
33_E227_Q1.1800.44
401_F448_R1.1760.44
6_Q530_L1.1750.44
65_L69_E1.1670.44
442_S561_M1.1630.43
137_Y212_I1.1620.43
152_E222_A1.1610.43
452_I496_K1.1610.43
336_E339_R1.1590.43
388_I579_Q1.1550.43
85_S90_E1.1540.43
56_M478_P1.1440.42
439_I443_I1.1420.42
316_F337_V1.1360.42
494_I514_D1.1350.42
219_E361_I1.1340.42
395_T496_K1.1330.42
395_T505_I1.1330.42
212_I216_L1.1320.42
319_A322_M1.1310.42
181_V345_Q1.1310.42
399_L425_Y1.1310.42
335_E338_H1.1300.42
295_C349_E1.1280.41
27_V372_A1.1250.41
177_T180_H1.1240.41
188_E193_D1.1200.41
148_Y214_P1.1150.41
273_M289_K1.1120.41
192_D248_E1.1110.41
275_V314_T1.1100.41
240_R248_E1.1070.40
148_Y252_L1.1030.40
175_A178_A1.1010.40
464_N514_D1.1000.40
127_I365_M1.0970.40
316_F334_S1.0930.40
400_Q490_P1.0880.39
377_K381_E1.0820.39
302_F379_M1.0800.39
42_E57_E1.0770.39
299_K569_T1.0760.39
515_E522_F1.0750.39
253_S566_D1.0750.39
227_Q255_V1.0730.38
105_M477_E1.0730.38
482_E497_V1.0730.38
402_L500_I1.0720.38
576_V593_K1.0670.38
478_P511_I1.0670.38
210_N216_L1.0670.38
452_I569_T1.0650.38
388_I567_M1.0600.38
275_V321_A1.0580.38
164_G168_P1.0580.38
9_L287_I1.0550.38
496_K517_S1.0530.37
163_T266_F1.0520.37
535_A579_Q1.0500.37
129_Q371_K1.0500.37
189_D194_E1.0490.37
53_I226_A1.0470.37
189_D193_D1.0440.37
496_K502_K1.0430.37
157_R208_D1.0410.37
68_A72_A1.0390.37
121_K425_Y1.0370.37
522_F558_V1.0360.37
71_T75_D1.0350.36
502_K570_D1.0340.36
93_R104_E1.0330.36
108_V435_I1.0310.36
559_L610_F1.0260.36
129_Q300_K1.0260.36
395_T511_I1.0250.36
246_Q321_A1.0240.36
28_N32_P1.0230.36
574_E584_R1.0210.36
80_A86_S1.0170.36
497_V501_A1.0130.35
194_E202_D1.0120.35
361_I612_D1.0120.35
304_T319_A1.0010.35
537_T540_L0.9940.34
20_G23_T0.9930.34
57_E486_R0.9920.34
452_I518_H0.9920.34
143_Y272_S0.9920.34
131_Q137_Y0.9920.34
249_I266_F0.9910.34
15_R27_V0.9900.34
395_T457_I0.9880.34
505_I547_V0.9860.34
400_Q544_T0.9860.34
237_A243_A0.9820.34
379_M579_Q0.9810.34
395_T563_F0.9810.34
231_T248_E0.9800.34
9_L323_N0.9780.33
596_R601_P0.9770.33
240_R266_F0.9770.33
15_R33_E0.9750.33
26_E53_I0.9750.33
78_E84_L0.9730.33
178_A275_V0.9710.33
159_S556_A0.9650.33
238_K242_H0.9650.33
237_A294_Q0.9650.33
141_I264_K0.9640.33
159_S163_T0.9630.33
283_Q286_L0.9620.33
147_Q277_M0.9610.33
250_L316_F0.9610.33
13_V250_L0.9610.33
29_D45_I0.9600.33
209_D216_L0.9600.33
226_A229_V0.9590.33
142_T259_F0.9580.32
372_A380_V0.9580.32
95_T135_A0.9580.32
578_K581_D0.9560.32
457_I460_I0.9530.32
348_E566_D0.9530.32
483_L494_I0.9530.32
593_K603_R0.9460.32
33_E58_E0.9450.32
224_L255_V0.9450.32
514_D578_K0.9420.32
61_D65_L0.9410.32
507_M581_D0.9390.32
149_D195_D0.9390.32
150_R156_A0.9390.32
22_L344_L0.9360.31
119_I261_L0.9360.31
273_M553_A0.9340.31
439_I503_E0.9340.31
312_S357_Q0.9340.31
318_A492_D0.9310.31
137_Y466_I0.9310.31
500_I503_E0.9290.31
22_L48_I0.9280.31
273_M550_G0.9280.31
446_Q456_M0.9270.31
420_E425_Y0.9270.31
478_P547_V0.9250.31
489_M494_I0.9230.31
280_V340_A0.9230.31
158_L214_P0.9230.31
447_A460_I0.9230.31
290_L295_C0.9220.31
212_I245_A0.9200.31
322_M331_H0.9200.31
226_A233_D0.9190.31
241_S312_S0.9170.30
299_K302_F0.9160.30
94_T365_M0.9130.30
442_S568_N0.9110.30
9_L321_A0.9100.30
23_T119_I0.9090.30
231_T251_K0.9080.30
208_D211_S0.9080.30
42_E266_F0.9080.30
225_R229_V0.9050.30
141_I256_F0.9040.30
468_R504_P0.9040.30
474_M497_V0.9030.30
130_V270_V0.9010.30
459_T508_E0.9010.30
57_E214_P0.9010.30
420_E457_I0.8950.29
501_A582_V0.8950.29
540_L544_T0.8930.29
567_M570_D0.8920.29
15_R19_Q0.8920.29
401_F461_N0.8910.29
140_A278_D0.8900.29
395_T452_I0.8880.29
193_D232_R0.8880.29
75_D169_N0.8880.29
219_E223_E0.8840.29
280_V359_K0.8840.29
208_D216_L0.8830.29
422_R442_S0.8830.29
173_D178_A0.8770.29
219_E308_G0.8770.29
266_F553_A0.8760.29
500_I600_H0.8740.28
446_Q460_I0.8730.28
114_E511_I0.8710.28
173_D236_K0.8710.28
109_E608_R0.8670.28
140_A364_R0.8660.28
223_E227_Q0.8630.28
60_P66_M0.8630.28
174_L350_E0.8620.28
574_E593_K0.8620.28
128_N533_D0.8620.28
171_E179_T0.8610.28
321_A334_S0.8610.28
102_M514_D0.8600.28
360_D370_A0.8590.28
442_S609_S0.8560.28
376_K418_K0.8540.28
290_L317_N0.8530.27
218_R221_F0.8520.27
511_I542_A0.8520.27
192_D195_D0.8490.27
39_D605_E0.8460.27
357_Q542_A0.8440.27
245_A266_F0.8420.27
255_V347_I0.8400.27
305_L318_A0.8340.27
499_K561_M0.8330.27
456_M583_T0.8330.27
109_E302_F0.8310.26
159_S208_D0.8300.26
441_R584_R0.8300.26
460_I499_K0.8300.26
379_M567_M0.8290.26
557_K581_D0.8280.26
495_R552_T0.8280.26
156_A268_Y0.8280.26
307_T359_K0.8270.26
513_D567_M0.8260.26
424_G531_P0.8240.26
248_E251_K0.8230.26
157_R207_D0.8230.26
418_K583_T0.8230.26
572_T584_R0.8220.26
279_R351_T0.8220.26
16_G30_H0.8220.26
144_L289_K0.8210.26
472_Q487_M0.8210.26
143_Y150_R0.8210.26
237_A244_T0.8210.26
261_L270_V0.8200.26
44_I47_M0.8200.26
131_Q606_V0.8190.26
93_R100_M0.8180.26
447_A456_M0.8180.26
457_I468_R0.8180.26
517_S593_K0.8170.26
379_M471_L0.8160.26
362_N366_S0.8150.26
53_I478_P0.8120.26
12_L581_D0.8120.26
447_A468_R0.8080.25
509_T519_L0.8080.25
150_R343_K0.8040.25
60_P344_L0.8010.25
229_V233_D0.8000.25
61_D344_L0.8000.25
107_T538_E0.8000.25
233_D237_A0.7980.25
288_M494_I0.7980.25
235_I240_R0.7980.25
379_M513_D0.7970.25
520_G525_D0.7940.25
148_Y222_A0.7930.25
40_Q44_I0.7920.25
388_I420_E0.7910.25
41_I533_D0.7890.25
216_L220_K0.7870.25
156_A339_R0.7860.25
60_P63_D0.7850.24
560_R612_D0.7840.24
199_E241_S0.7830.24
154_E342_Q0.7830.24
537_T599_R0.7830.24
194_E294_Q0.7790.24
479_T536_T0.7780.24
125_D317_N0.7780.24
495_R609_S0.7770.24
102_M605_E0.7750.24
346_Q350_E0.7740.24
300_K332_D0.7730.24
328_E331_H0.7730.24
95_T464_N0.7720.24
552_T567_M0.7710.24
456_M576_V0.7710.24
420_E435_I0.7710.24
115_G122_R0.7690.24
36_V41_I0.7690.24
460_I509_T0.7670.24
99_R105_M0.7630.24
276_M280_V0.7620.24
9_L528_L0.7620.24
150_R153_A0.7610.23
266_F355_I0.7610.23
141_I228_Y0.7610.23
317_N338_H0.7610.23
161_L323_N0.7590.23
468_R500_I0.7580.23
596_R600_H0.7580.23
152_E219_E0.7580.23
9_L269_L0.7570.23
541_R545_H0.7560.23
482_E571_Y0.7540.23
501_A519_L0.7540.23
102_M464_N0.7530.23
322_M325_P0.7520.23
249_I606_V0.7520.23
162_I265_Q0.7520.23
36_V484_A0.7510.23
400_Q571_Y0.7500.23
581_D605_E0.7490.23
188_E195_D0.7490.23
6_Q566_D0.7470.23
141_I606_V0.7470.23
168_P172_E0.7460.23
42_E49_N0.7450.23
372_A452_I0.7450.23
176_P181_V0.7440.23
84_L88_E0.7440.23
488_L530_L0.7430.23
457_I570_D0.7420.23
501_A576_V0.7420.23
8_Q11_L0.7420.23
238_K245_A0.7410.23
54_Q64_D0.7410.23
239_G245_A0.7390.23
130_V213_D0.7390.23
178_A250_L0.7380.23
513_D522_F0.7370.23
35_I50_D0.7350.22
499_K520_G0.7330.22
106_G558_V0.7310.22
400_Q459_T0.7290.22
496_K511_I0.7290.22
273_M484_A0.7280.22
435_I558_V0.7280.22
401_F438_A0.7280.22
212_I538_E0.7280.22
126_G460_I0.7260.22
570_D575_E0.7260.22
273_M489_M0.7250.22
174_L188_E0.7230.22
131_Q299_K0.7230.22
509_T581_D0.7230.22
180_H190_L0.7220.22
127_I528_L0.7200.22
44_I57_E0.7180.22
302_F489_M0.7180.22
18_E22_L0.7170.22
557_K602_S0.7160.22
368_G372_A0.7150.22
30_H297_M0.7150.22
19_Q26_E0.7140.22
149_D181_V0.7140.22
400_Q570_D0.7140.22
447_A508_E0.7120.22
223_E236_K0.7110.22
109_E561_M0.7110.22
425_Y502_K0.7110.22
121_K570_D0.7100.21
181_V190_L0.7090.21
16_G92_G0.7090.21
558_V590_I0.7080.21
603_R610_F0.7080.21
226_A356_E0.7070.21
580_F583_T0.7040.21
596_R604_S0.7040.21
77_A321_A0.7040.21
159_S606_V0.7010.21
12_L79_A0.7000.21
314_T334_S0.6970.21
20_G26_E0.6970.21
72_A88_E0.6960.21
141_I145_L0.6960.21
146_E152_E0.6940.21
151_V160_D0.6930.21
156_A350_E0.6920.21
529_E532_L0.6910.21
297_M319_A0.6900.21
148_Y261_L0.6900.21
491_E505_I0.6900.21
80_A296_K0.6900.21
148_Y225_R0.6870.21
210_N259_F0.6850.21
339_R533_D0.6850.21
107_T511_I0.6840.20
6_Q210_N0.6840.20
83_V330_L0.6820.20
50_D535_A0.6810.20
526_T605_E0.6800.20
36_V128_N0.6800.20
128_N273_M0.6800.20
71_T200_D0.6790.20
151_V252_L0.6770.20
107_T318_A0.6770.20
339_R343_K0.6770.20
92_G374_R0.6760.20
19_Q300_K0.6750.20
126_G401_F0.6750.20
300_K304_T0.6750.20
140_A566_D0.6750.20
459_T502_K0.6740.20
351_T354_T0.6740.20
499_K502_K0.6730.20
88_E144_L0.6730.20
425_Y473_E0.6730.20
118_D133_S0.6720.20
95_T557_K0.6720.20
515_E600_H0.6710.20
457_I520_G0.6680.20
498_L543_A0.6680.20
286_L336_E0.6680.20
26_E352_G0.6670.20
132_C270_V0.6650.20
133_S488_L0.6650.20
118_D537_T0.6640.20
27_V515_E0.6630.20
499_K524_E0.6630.20
207_D210_N0.6620.20
211_S463_L0.6620.20
125_D611_L0.6600.20
304_T340_A0.6600.20
422_R567_M0.6600.20
496_K596_R0.6590.20
135_A253_S0.6590.20
242_H514_D0.6590.20
70_N223_E0.6580.20
133_S277_M0.6580.20
502_K565_I0.6570.19
299_K379_M0.6560.19
284_E541_R0.6560.19
36_V47_M0.6550.19
250_L380_V0.6540.19
508_E570_D0.6500.19
153_A268_Y0.6500.19
544_T571_Y0.6490.19
167_D172_E0.6480.19
511_I570_D0.6480.19
399_L505_I0.6470.19
154_E305_L0.6470.19
77_A478_P0.6460.19
249_I357_Q0.6460.19
39_D53_I0.6460.19
400_Q518_H0.6460.19
273_M529_E0.6430.19
126_G448_R0.6420.19
444_A459_T0.6410.19
44_I362_N0.6410.19
326_W546_D0.6410.19
60_P102_M0.6390.19
77_A177_T0.6390.19
496_K544_T0.6380.19
24_Y41_I0.6380.19
368_G395_T0.6370.19
489_M543_A0.6370.19
24_Y608_R0.6360.19
517_S596_R0.6350.19
400_Q496_K0.6340.19
145_L256_F0.6330.19
46_Q266_F0.6310.19
368_G517_S0.6300.19
132_C142_T0.6290.19
435_I503_E0.6290.19
114_E503_E0.6290.19
400_Q509_T0.6280.18
127_I277_M0.6270.18
548_L572_T0.6260.18
148_Y272_S0.6260.18
13_V192_D0.6250.18
91_I134_V0.6250.18
94_T579_Q0.6230.18
470_M612_D0.6230.18
400_Q500_I0.6220.18
169_N173_D0.6220.18
48_I300_K0.6200.18
68_A349_E0.6200.18
148_Y156_A0.6190.18
163_T463_L0.6190.18
180_H321_A0.6170.18
227_Q230_V0.6170.18
117_I483_L0.6160.18
395_T447_A0.6160.18
439_I592_A0.6150.18
402_L600_H0.6150.18
459_T522_F0.6150.18
435_I592_A0.6140.18
31_L51_M0.6140.18
512_G574_E0.6140.18
158_L209_D0.6130.18
179_T303_I0.6110.18
452_I460_I0.6100.18
33_E91_I0.6100.18
388_I400_Q0.6100.18
294_Q338_H0.6090.18
303_I310_E0.6080.18
122_R480_P0.6080.18
79_A484_A0.6050.18
41_I371_K0.6050.18
295_C316_F0.6040.18
496_K500_I0.6020.18
172_E175_A0.6020.18
232_R344_L0.6010.18
302_F315_W0.6010.18
299_K357_Q0.6000.18
133_S136_E0.6000.18
58_E244_T0.6000.18
106_G381_E0.6000.18
494_I541_R0.5990.18
259_F486_R0.5990.18
38_S303_I0.5990.18
294_Q342_Q0.5960.17
142_T276_M0.5940.17
100_M103_R0.5920.17
417_D420_E0.5890.17
67_L70_N0.5890.17
402_L413_M0.5880.17
459_T570_D0.5880.17
311_T341_L0.5870.17
14_T85_S0.5870.17
181_V304_T0.5870.17
78_E145_L0.5850.17
363_R367_I0.5840.17
41_I553_A0.5830.17
194_E197_D0.5830.17
561_M602_S0.5820.17
129_Q377_K0.5810.17
439_I517_S0.5810.17
119_I393_K0.5810.17
156_A301_N0.5800.17
504_P525_D0.5790.17
18_E92_G0.5790.17
594_A598_L0.5780.17
312_S360_D0.5780.17
200_D484_A0.5770.17
180_H198_E0.5770.17
52_G55_V0.5750.17
131_Q249_I0.5740.17
28_N515_E0.5740.17
152_E218_R0.5740.17
288_M515_E0.5740.17
522_F547_V0.5740.17
435_I457_I0.5720.17
22_L27_V0.5720.17
159_S209_D0.5720.17
523_I587_I0.5710.17
109_E560_R0.5710.17
108_V395_T0.5710.17
57_E463_L0.5700.17
358_V367_I0.5700.17
499_K558_V0.5690.17
252_L303_I0.5680.17
526_T539_S0.5680.17
9_L492_D0.5680.17
402_L460_I0.5670.16
393_K561_M0.5660.16
487_M523_I0.5660.16
143_Y290_L0.5660.16
466_I578_K0.5620.16
261_L341_L0.5620.16
328_E487_M0.5610.16
418_K441_R0.5610.16
459_T497_V0.5600.16
163_T167_D0.5600.16
162_I355_I0.5590.16
29_D278_D0.5590.16
395_T435_I0.5580.16
73_D83_V0.5570.16
221_F259_F0.5570.16
119_I466_I0.5560.16
15_R35_I0.5560.16
188_E226_A0.5560.16
148_Y210_N0.5560.16
379_M464_N0.5530.16
78_E484_A0.5530.16
435_I516_D0.5530.16
43_D484_A0.5530.16
112_T472_Q0.5510.16
400_Q457_I0.5510.16
459_T582_V0.5500.16
559_L565_I0.5490.16
244_T342_Q0.5480.16
468_R508_E0.5470.16
44_I74_E0.5470.16
163_T339_R0.5460.16
541_R607_L0.5460.16
316_F336_E0.5460.16
115_G511_I0.5450.16
266_F339_R0.5450.16
84_L365_M0.5440.16
378_E552_T0.5430.16
513_D517_S0.5420.16
179_T244_T0.5420.16
147_Q292_V0.5410.16
146_E149_D0.5410.16
495_R535_A0.5400.16
118_D134_V0.5400.16
9_L17_K0.5400.16
402_L446_Q0.5400.16
69_E72_A0.5390.16
381_E596_R0.5390.16
119_I505_I0.5380.16
79_A82_Q0.5380.16
381_E388_I0.5380.16
503_E604_S0.5380.16
130_V358_V0.5370.16
301_N304_T0.5370.16
490_P500_I0.5370.16
568_N579_Q0.5350.15
314_T318_A0.5350.15
220_K223_E0.5340.15
368_G399_L0.5330.15
66_M311_T0.5320.15
94_T99_R0.5310.15
509_T563_F0.5300.15
36_V273_M0.5290.15
70_N73_D0.5290.15
502_K600_H0.5290.15
476_R528_L0.5280.15
425_Y435_I0.5270.15
167_D170_A0.5270.15
467_S480_P0.5270.15
128_N220_K0.5270.15
226_A331_H0.5260.15
556_A566_D0.5260.15
12_L380_V0.5260.15
67_L154_E0.5260.15
38_S515_E0.5250.15
100_M104_E0.5240.15
421_Y425_Y0.5240.15
467_S519_L0.5230.15
48_I334_S0.5210.15
321_A337_V0.5210.15
130_V137_Y0.5210.15
348_E545_H0.5200.15
39_D335_E0.5200.15
395_T399_L0.5200.15
299_K310_E0.5200.15
443_I468_R0.5200.15
233_D356_E0.5200.15
417_D473_E0.5200.15
287_I337_V0.5190.15
273_M488_L0.5180.15
212_I218_R0.5180.15
252_L296_K0.5180.15
396_N418_K0.5180.15
395_T460_I0.5180.15
457_I477_E0.5180.15
448_R457_I0.5170.15
121_K496_K0.5160.15
209_D213_D0.5160.15
245_A267_D0.5150.15
88_E530_L0.5150.15
91_I341_L0.5140.15
438_A468_R0.5140.15
33_E251_K0.5140.15
367_I371_K0.5140.15
195_D331_H0.5140.15
75_D273_M0.5130.15
8_Q128_N0.5130.15
413_M565_I0.5130.15
74_E84_L0.5130.15
171_E174_L0.5130.15
139_E276_M0.5120.15
78_E81_A0.5120.15
501_A509_T0.5110.15
441_R572_T0.5110.15
46_Q88_E0.5100.15
390_I420_E0.5100.15
547_V561_M0.5090.15
511_I605_E0.5090.15
565_I608_R0.5080.15
57_E61_D0.5080.15
496_K522_F0.5080.15
278_D297_M0.5070.15
39_D290_L0.5070.15
464_N561_M0.5070.15
215_E219_E0.5060.15
452_I499_K0.5060.15
469_Q592_A0.5050.15
27_V474_M0.5040.15
41_I59_A0.5040.15
582_V587_I0.5030.15
262_V340_A0.5030.15
229_V322_M0.5030.15
165_F273_M0.5030.15
512_G583_T0.5020.15
131_Q212_I0.5010.15
233_D349_E0.5010.15
476_R479_T0.5000.14
508_E517_S0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4yfkF 1 0.7651 100 0.413 Contact Map
1l9zH 1 0.5155 100 0.703 Contact Map
2a6hF 1 0.5579 100 0.706 Contact Map
1sigA 1 0.4959 100 0.722 Contact Map
3ugoA 1 0.2936 100 0.828 Contact Map
1l0oC 1 0.093 100 0.87 Contact Map
1rp3A 1 0.3736 100 0.874 Contact Map
4x8kA 1 0.199 99.8 0.924 Contact Map
4nqwA 1 0.2414 99.6 0.934 Contact Map
3mzyA 1 0.1958 99.6 0.936 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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