GREMLIN Database
PTM3C - PTS system mannitol-specific EIICBA component
UniProt: P00550 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10615
Length: 637 (618)
Sequences: 265 (167)
Seq/√Len: 6.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
279_T321_A5.1920.99
227_V273_V5.1070.99
289_G315_N5.0820.99
434_T448_S4.9030.99
275_L329_V4.3340.97
284_L318_G3.9940.95
537_D540_K3.8970.95
51_L90_V3.7670.94
625_S628_E3.6390.92
534_A559_A3.5470.91
519_E523_K3.4500.90
304_L316_I3.3150.88
500_N526_Y3.2740.87
357_A361_G3.1320.85
65_G85_T3.1100.84
181_V217_I3.0960.84
566_T603_V3.0180.82
181_V198_F2.9820.82
272_A330_S2.9700.81
578_R581_E2.8710.79
357_A360_K2.7900.77
572_Q579_F2.7550.76
287_L314_A2.6550.73
12_F15_F2.6500.73
588_R621_A2.6010.71
345_I356_K2.5840.71
108_G142_L2.5140.69
275_L330_S2.4730.67
178_S281_V2.4700.67
379_K423_D2.4550.67
287_L317_A2.4220.66
328_V332_I2.3260.62
266_N337_S2.3010.61
186_I273_V2.2910.61
498_A627_D2.2750.61
523_K577_V2.2100.58
113_H116_R2.1850.57
508_A512_E2.1830.57
219_A294_P2.1780.57
271_L275_L2.1760.57
251_F319_V2.1490.56
595_A604_I2.1280.55
25_G187_L2.1250.55
38_I52_V2.1200.55
198_F217_I2.0930.54
45_N48_L2.0690.53
345_I348_A2.0580.53
289_G314_A2.0560.52
114_F118_V2.0520.52
504_G587_A2.0510.52
563_V591_I2.0480.52
162_A197_I2.0350.52
504_G620_L2.0190.51
14_R214_F2.0070.51
283_T321_A2.0020.50
62_L86_M1.9970.50
248_I252_L1.9630.49
121_K438_M1.9450.48
94_M154_V1.9380.48
570_F603_V1.9100.47
180_F197_I1.9050.47
349_T352_M1.8990.47
80_V556_T1.8880.46
380_I537_D1.8820.46
103_A244_G1.8710.46
566_T595_A1.8650.45
528_E562_R1.8520.45
304_L307_T1.8300.44
150_I173_M1.8230.44
322_A326_S1.8210.44
597_N604_I1.8160.44
546_L608_T1.8140.43
287_L311_A1.8130.43
548_E608_T1.7630.42
289_G311_A1.7630.42
580_G621_A1.7610.41
400_K434_T1.7590.41
203_I215_F1.7370.41
284_L597_N1.7370.41
530_E562_R1.7310.40
607_L617_I1.7280.40
597_N626_V1.7260.40
377_V426_L1.7250.40
401_K405_A1.7170.40
25_G132_N1.6990.39
548_E617_I1.6910.39
27_F95_P1.6820.39
513_A573_Y1.6760.38
522_V532_V1.6670.38
46_E50_K1.6630.38
224_G256_H1.6310.37
502_F516_F1.6250.37
352_M355_M1.6240.37
526_Y579_F1.6240.37
557_V611_L1.6210.36
36_L43_L1.6150.36
48_L144_I1.6020.36
568_V587_A1.5990.36
333_L566_T1.5940.36
507_A573_Y1.5940.36
417_I420_L1.5870.35
268_R333_L1.5770.35
300_I319_V1.5700.35
611_L623_T1.5620.34
434_T446_H1.5510.34
458_Y462_T1.5450.34
348_A356_K1.5320.33
528_E564_L1.5290.33
568_V597_N1.5220.33
186_I263_V1.5200.33
114_F138_I1.5190.33
108_G111_I1.5100.33
568_V612_D1.5060.33
334_L458_Y1.4940.32
586_I589_L1.4910.32
206_S381_I1.4820.32
541_L582_E1.4780.32
197_I614_E1.4760.32
27_F57_T1.4730.32
164_G545_Y1.4700.31
265_M302_A1.4680.31
382_V456_G1.4640.31
144_I197_I1.4610.31
27_F33_I1.4580.31
33_I95_P1.4520.31
268_R633_L1.4490.31
268_R566_T1.4440.31
62_L530_E1.4390.30
586_I630_L1.4340.30
214_F396_G1.4290.30
505_R623_T1.4240.30
573_Y590_V1.4220.30
199_S203_I1.4220.30
182_E256_H1.4190.30
498_A564_L1.4170.30
549_S597_N1.4150.30
515_R536_L1.4140.30
563_V586_I1.4100.29
92_A160_M1.4070.29
86_M90_V1.4050.29
545_Y574_P1.3960.29
113_H495_K1.3930.29
201_L214_F1.3920.29
284_L289_G1.3840.29
545_Y572_Q1.3820.29
520_Q523_K1.3750.28
335_K380_I1.3700.28
312_Y316_I1.3690.28
550_I572_Q1.3650.28
546_L633_L1.3580.28
26_A79_V1.3570.28
578_R623_T1.3550.28
546_L556_T1.3540.28
332_I336_T1.3530.28
447_I456_G1.3460.28
533_Q580_G1.3420.27
327_F393_M1.3370.27
163_A625_S1.3350.27
404_D408_S1.3340.27
571_C595_A1.3340.27
519_E529_P1.3310.27
534_A562_R1.3300.27
108_G465_L1.3300.27
239_A398_L1.3190.27
523_K613_D1.3120.27
398_L458_Y1.3120.27
179_I213_I1.3120.27
216_L237_G1.3080.26
217_I382_V1.3080.26
539_E591_I1.3050.26
613_D619_R1.2980.26
550_I611_L1.2980.26
277_G405_A1.2960.26
51_L88_V1.2930.26
289_G316_I1.2900.26
608_T612_D1.2890.26
11_S591_I1.2820.26
80_V135_A1.2810.26
110_C138_I1.2780.26
116_R119_D1.2740.25
603_V629_V1.2660.25
571_C603_V1.2620.25
168_M284_L1.2620.25
627_D631_E1.2610.25
533_Q537_D1.2600.25
201_L454_D1.2550.25
168_M294_P1.2500.25
74_G151_G1.2500.25
577_V627_D1.2480.25
42_W304_L1.2470.25
526_Y567_G1.2380.24
324_A328_V1.2370.24
557_V616_V1.2360.24
445_Q464_R1.2350.24
394_G452_F1.2240.24
328_V499_E1.2130.24
288_G354_D1.2110.24
275_L504_G1.2090.24
144_I149_G1.2080.24
624_T632_L1.2050.24
180_F205_Q1.2040.23
215_F293_S1.2020.23
182_E224_G1.2020.23
122_I131_N1.2000.23
429_T448_S1.1990.23
216_L303_V1.1990.23
505_R620_L1.1980.23
541_L563_V1.1910.23
25_G57_T1.1900.23
185_K218_E1.1820.23
591_I616_V1.1800.23
546_L563_V1.1780.23
132_N187_L1.1760.23
548_E612_D1.1740.23
169_V302_A1.1720.23
579_F589_L1.1650.22
587_A621_A1.1600.22
28_I262_Y1.1600.22
570_F629_V1.1500.22
496_L603_V1.1490.22
627_D633_L1.1490.22
271_L519_E1.1470.22
398_L449_L1.1460.22
572_Q611_L1.1460.22
397_V458_Y1.1440.22
19_M30_W1.1440.22
48_L161_L1.1420.22
156_A180_F1.1420.22
322_A381_I1.1410.22
382_V418_N1.1400.22
603_V630_L1.1390.22
537_D605_T1.1370.22
569_V573_Y1.1370.22
317_A542_T1.1370.22
39_P45_N1.1350.22
10_Q16_L1.1330.22
528_E563_V1.1320.22
21_M56_I1.1290.22
420_L462_T1.1280.21
618_E631_E1.1240.21
33_I60_L1.1230.21
199_S214_F1.1230.21
151_G313_F1.1220.21
548_E595_A1.1210.21
120_G123_K1.1210.21
62_L90_V1.1180.21
186_I330_S1.1150.21
549_S568_V1.1040.21
60_L97_F1.1030.21
582_E612_D1.1010.21
603_V608_T1.1010.21
62_L273_V1.0990.21
548_E611_L1.0980.21
18_N71_L1.0980.21
523_K619_R1.0970.21
103_A146_A1.0910.21
596_R626_V1.0890.21
380_I485_S1.0830.20
62_L186_I1.0800.20
242_S616_V1.0790.20
185_K224_G1.0770.20
598_N605_T1.0760.20
377_V402_I1.0740.20
316_I380_I1.0730.20
182_E185_K1.0730.20
334_L617_I1.0690.20
48_L129_L1.0680.20
504_G605_T1.0680.20
577_V631_E1.0670.20
198_F569_V1.0630.20
546_L603_V1.0610.20
579_F587_A1.0610.20
549_S586_I1.0600.20
185_K256_H1.0590.20
242_S536_L1.0580.20
401_K455_S1.0580.20
493_L523_K1.0580.20
586_I622_H1.0570.20
616_V623_T1.0560.20
453_L541_L1.0560.20
18_N219_A1.0540.20
19_M22_P1.0530.20
401_K458_Y1.0520.20
214_F449_L1.0490.20
550_I590_V1.0470.20
244_G595_A1.0430.19
518_G532_V1.0400.19
73_G250_H1.0400.19
277_G280_G1.0400.19
285_T438_M1.0390.19
461_L541_L1.0380.19
552_V604_I1.0370.19
428_I461_L1.0350.19
155_E605_T1.0340.19
505_R572_Q1.0330.19
197_I358_E1.0280.19
56_I186_I1.0250.19
92_A155_E1.0250.19
595_A608_T1.0250.19
586_I608_T1.0230.19
546_L611_L1.0230.19
182_E221_P1.0220.19
45_N50_K1.0170.19
453_L579_F1.0120.19
227_V330_S1.0110.19
97_F237_G1.0110.19
567_G579_F1.0090.19
130_V275_L1.0090.19
546_L623_T1.0080.19
501_I629_V1.0060.19
137_I141_I1.0040.19
34_T91_G1.0030.18
557_V608_T1.0010.18
280_G429_T1.0000.18
225_M501_I0.9980.18
333_L430_H0.9980.18
573_Y620_L0.9970.18
353_Q360_K0.9970.18
141_I577_V0.9950.18
181_V281_V0.9950.18
18_N568_V0.9940.18
548_E604_I0.9910.18
577_V587_A0.9910.18
526_Y589_L0.9900.18
168_M537_D0.9860.18
572_Q589_L0.9840.18
135_A277_G0.9820.18
611_L616_V0.9820.18
214_F623_T0.9820.18
601_I608_T0.9740.18
524_G568_V0.9740.18
273_V277_G0.9740.18
523_K587_A0.9730.18
580_G612_D0.9720.18
94_M158_S0.9720.18
194_N199_S0.9720.18
59_L85_T0.9710.18
121_K558_E0.9680.18
431_R597_N0.9650.18
219_A303_V0.9630.18
118_V122_I0.9610.18
542_T556_T0.9600.18
328_V599_E0.9600.18
461_L591_I0.9590.18
556_T563_V0.9590.18
310_G316_I0.9570.17
539_E544_T0.9560.17
123_K231_Y0.9520.17
59_L82_A0.9520.17
438_M628_E0.9510.17
168_M199_S0.9510.17
70_K120_G0.9500.17
548_E628_E0.9490.17
572_Q587_A0.9490.17
568_V598_N0.9490.17
618_E622_H0.9480.17
516_F520_Q0.9480.17
333_L403_Q0.9460.17
151_G545_Y0.9460.17
148_L180_F0.9440.17
598_N613_D0.9410.17
53_G302_A0.9360.17
263_V426_L0.9350.17
381_I401_K0.9340.17
401_K448_S0.9330.17
329_V632_L0.9330.17
219_A295_A0.9310.17
514_I518_G0.9290.17
284_L617_I0.9280.17
71_L98_L0.9270.17
539_E590_V0.9270.17
515_R533_Q0.9240.17
277_G446_H0.9230.17
216_L239_A0.9210.17
289_G507_A0.9200.17
542_T616_V0.9160.17
287_L633_L0.9150.17
68_G265_M0.9150.17
107_G154_V0.9140.17
552_V578_R0.9110.17
453_L461_L0.9090.16
514_I535_M0.9090.16
529_P568_V0.9070.16
199_S294_P0.9020.16
44_P76_R0.9010.16
339_V615_S0.9010.16
557_V599_E0.8980.16
296_S306_M0.8980.16
156_A328_V0.8980.16
282_F285_T0.8970.16
245_G251_F0.8960.16
529_P558_E0.8960.16
581_E612_D0.8960.16
220_N395_A0.8920.16
129_L194_N0.8900.16
345_I352_M0.8890.16
88_V178_S0.8860.16
168_M556_T0.8850.16
563_V596_R0.8850.16
549_S603_V0.8840.16
316_I320_C0.8840.16
185_K221_P0.8840.16
233_F329_V0.8830.16
569_V589_L0.8820.16
113_H515_R0.8810.16
84_T382_V0.8800.16
217_I595_A0.8800.16
97_F154_V0.8790.16
280_G446_H0.8770.16
56_I434_T0.8760.16
393_M607_L0.8740.16
599_E616_V0.8730.16
598_N620_L0.8730.16
566_T604_I0.8720.16
550_I589_L0.8710.16
589_L621_A0.8710.16
43_L354_D0.8700.16
278_M282_F0.8690.16
18_N612_D0.8680.16
235_G239_A0.8660.16
284_L307_T0.8650.16
597_N610_A0.8620.16
24_I28_I0.8610.15
199_S579_F0.8610.15
293_S417_I0.8610.15
602_Q609_N0.8600.15
548_E603_V0.8590.15
541_L557_V0.8590.15
273_V283_T0.8580.15
599_E612_D0.8580.15
601_I605_T0.8580.15
182_E218_E0.8580.15
18_N400_K0.8580.15
549_S588_R0.8570.15
588_R612_D0.8560.15
240_K301_L0.8560.15
157_L288_G0.8550.15
557_V604_I0.8540.15
269_L277_G0.8530.15
25_G95_P0.8530.15
610_A623_T0.8520.15
53_G171_H0.8480.15
198_F633_L0.8480.15
32_I137_I0.8470.15
358_E463_E0.8460.15
494_F626_V0.8460.15
431_R598_N0.8450.15
589_L625_S0.8440.15
16_L68_G0.8430.15
177_A307_T0.8430.15
214_F612_D0.8420.15
178_S278_M0.8410.15
56_I417_I0.8410.15
576_G588_R0.8410.15
564_L596_R0.8400.15
571_C623_T0.8390.15
157_L161_L0.8380.15
524_G564_L0.8370.15
548_E571_C0.8360.15
529_P533_Q0.8350.15
310_G465_L0.8310.15
458_Y548_E0.8290.15
239_A294_P0.8270.15
154_V280_G0.8250.15
75_E140_M0.8230.15
581_E621_A0.8230.15
426_L574_P0.8220.15
557_V620_L0.8220.15
591_I610_A0.8220.15
263_V273_V0.8220.15
469_Q563_V0.8200.15
380_I402_I0.8170.15
501_I597_N0.8160.15
523_K627_D0.8160.15
505_R571_C0.8130.15
40_T72_V0.8130.15
136_G165_V0.8110.15
532_V619_R0.8100.15
185_K291_L0.8100.15
541_L572_Q0.8090.14
596_R632_L0.8070.14
91_G146_A0.8050.14
161_L563_V0.8020.14
360_K578_R0.8000.14
455_S458_Y0.8000.14
568_V630_L0.8000.14
401_K434_T0.8000.14
240_K545_Y0.7990.14
51_L78_G0.7970.14
456_G459_T0.7960.14
579_F617_I0.7960.14
523_K570_F0.7950.14
21_M64_I0.7940.14
571_C608_T0.7940.14
121_K607_L0.7930.14
24_I271_L0.7900.14
161_L164_G0.7890.14
358_E361_G0.7880.14
495_K602_Q0.7880.14
545_Y579_F0.7850.14
78_G351_R0.7850.14
529_P633_L0.7840.14
97_F406_G0.7840.14
166_N305_A0.7830.14
300_I330_S0.7830.14
355_M426_L0.7790.14
52_V302_A0.7780.14
536_L580_G0.7780.14
502_F605_T0.7770.14
498_A562_R0.7760.14
12_F25_G0.7750.14
211_K240_K0.7710.14
14_R455_S0.7680.14
148_L590_V0.7670.14
27_F132_N0.7670.14
523_K575_E0.7670.14
303_V318_G0.7650.14
179_I184_A0.7640.14
24_I218_E0.7640.14
571_C612_D0.7630.14
41_G44_P0.7610.14
131_N414_N0.7600.14
586_I602_Q0.7590.14
23_N37_F0.7590.14
153_I479_K0.7580.14
587_A612_D0.7570.14
40_T296_S0.7560.14
344_D537_D0.7530.13
219_A517_A0.7530.13
530_E558_E0.7520.13
505_R569_V0.7510.13
287_L315_N0.7490.13
595_A603_V0.7490.13
221_P256_H0.7480.13
576_G630_L0.7470.13
113_H152_P0.7460.13
549_S611_L0.7440.13
236_R378_R0.7440.13
601_I604_I0.7430.13
241_Q533_Q0.7400.13
552_V608_T0.7400.13
72_V295_A0.7400.13
548_E582_E0.7390.13
123_K396_G0.7380.13
92_A324_A0.7370.13
581_E623_T0.7370.13
610_A628_E0.7350.13
84_T244_G0.7310.13
402_I420_L0.7300.13
252_L492_N0.7300.13
606_S632_L0.7290.13
611_L620_L0.7280.13
343_D511_E0.7280.13
570_F624_T0.7270.13
568_V591_I0.7270.13
549_S557_V0.7270.13
476_E479_K0.7270.13
330_S334_L0.7260.13
161_L179_I0.7260.13
95_P132_N0.7230.13
20_V65_G0.7230.13
340_K533_Q0.7210.13
484_D490_S0.7200.13
349_T625_S0.7180.13
546_L609_N0.7180.13
502_F564_L0.7180.13
13_G16_L0.7180.13
188_F191_N0.7170.13
559_A626_V0.7160.13
147_F328_V0.7150.13
253_G386_A0.7130.13
516_F556_T0.7130.13
338_K530_E0.7130.13
154_V215_F0.7120.13
304_L312_Y0.7110.13
591_I611_L0.7110.13
526_Y613_D0.7100.13
167_F590_V0.7100.13
505_R536_L0.7100.13
610_A625_S0.7090.13
45_N49_A0.7080.13
224_G262_Y0.7070.13
401_K418_N0.7060.13
62_L283_T0.7060.13
552_V557_V0.7060.13
495_K629_V0.7040.13
221_P224_G0.7030.13
123_K564_L0.7010.13
8_K144_I0.7010.13
24_I182_E0.7010.13
550_I612_D0.7000.13
201_L591_I0.6980.13
566_T608_T0.6980.13
270_I273_V0.6970.13
530_E631_E0.6970.13
186_I270_I0.6960.13
446_H544_T0.6950.12
466_V567_G0.6950.12
198_F291_L0.6940.12
295_A301_L0.6940.12
20_V567_G0.6930.12
517_A521_L0.6930.12
65_G97_F0.6930.12
36_L138_I0.6920.12
181_V382_V0.6920.12
329_V344_D0.6910.12
137_I264_L0.6910.12
307_T312_Y0.6910.12
569_V625_S0.6910.12
565_K619_R0.6900.12
587_A597_N0.6900.12
357_A629_V0.6890.12
524_G570_F0.6890.12
307_T315_N0.6890.12
629_V632_L0.6890.12
271_L406_G0.6890.12
55_M62_L0.6880.12
595_A601_I0.6860.12
625_S632_L0.6850.12
203_I292_V0.6840.12
84_T595_A0.6830.12
550_I604_I0.6830.12
249_I261_P0.6830.12
149_G596_R0.6810.12
280_G283_T0.6800.12
311_A315_N0.6800.12
292_V309_K0.6800.12
227_V258_I0.6790.12
56_I318_G0.6780.12
171_H605_T0.6780.12
241_Q582_E0.6760.12
218_E256_H0.6750.12
158_S304_L0.6750.12
67_T276_G0.6750.12
135_A446_H0.6750.12
512_E606_S0.6740.12
83_I242_S0.6740.12
130_V173_M0.6720.12
315_N559_A0.6710.12
376_H523_K0.6700.12
381_I500_N0.6700.12
453_L563_V0.6700.12
548_E557_V0.6690.12
507_A561_D0.6680.12
453_L572_Q0.6680.12
211_K564_L0.6670.12
73_G449_L0.6660.12
147_F247_A0.6650.12
18_N98_L0.6650.12
21_M30_W0.6650.12
559_A599_E0.6650.12
586_I621_A0.6650.12
619_R628_E0.6640.12
520_Q601_I0.6620.12
32_I171_H0.6620.12
109_W361_G0.6610.12
197_I451_N0.6600.12
329_V540_K0.6590.12
22_P81_G0.6590.12
557_V603_V0.6580.12
586_I603_V0.6580.12
10_Q19_M0.6580.12
204_Q353_Q0.6560.12
416_A449_L0.6560.12
70_K209_L0.6550.12
294_P563_V0.6550.12
506_K618_E0.6540.12
351_R371_T0.6540.12
73_G266_N0.6510.12
414_N446_H0.6500.12
13_G37_F0.6470.12
98_L287_L0.6460.12
546_L557_V0.6450.12
540_K629_V0.6450.12
71_L146_A0.6440.12
50_K57_T0.6430.12
552_V595_A0.6420.12
102_I247_A0.6410.12
455_S617_I0.6410.12
250_H256_H0.6410.12
501_I558_E0.6410.12
216_L269_L0.6370.12
27_F36_L0.6370.12
10_Q13_G0.6360.12
96_M200_P0.6360.12
557_V612_D0.6360.12
113_H629_V0.6360.12
498_A630_L0.6350.12
133_F246_A0.6340.12
457_L550_I0.6340.12
548_E629_V0.6340.12
237_G269_L0.6330.12
417_I462_T0.6330.12
396_G466_V0.6330.12
301_L430_H0.6320.11
546_L595_A0.6300.11
14_R505_R0.6280.11
190_N196_G0.6270.11
421_P424_V0.6260.11
566_T571_C0.6250.11
18_N633_L0.6250.11
225_M236_R0.6250.11
546_L552_V0.6240.11
20_V40_T0.6240.11
110_C313_F0.6240.11
40_T463_E0.6230.11
307_T398_L0.6230.11
335_K514_I0.6220.11
579_F588_R0.6210.11
557_V591_I0.6200.11
150_I591_I0.6200.11
56_I431_R0.6200.11
236_R285_T0.6200.11
453_L608_T0.6190.11
608_T617_I0.6190.11
523_K582_E0.6180.11
86_M321_A0.6180.11
91_G545_Y0.6180.11
258_I322_A0.6180.11
150_I566_T0.6180.11
449_L604_I0.6170.11
289_G307_T0.6170.11
611_L630_L0.6170.11
46_E62_L0.6160.11
256_H262_Y0.6150.11
214_F455_S0.6150.11
546_L630_L0.6140.11
118_V121_K0.6130.11
540_K565_K0.6130.11
534_A615_S0.6100.11
530_E613_D0.6090.11
17_S394_G0.6080.11
397_V453_L0.6070.11
350_R526_Y0.6070.11
405_A458_Y0.6070.11
231_Y266_N0.6060.11
605_T626_V0.6050.11
611_L633_L0.6050.11
208_E345_I0.6040.11
560_K620_L0.6040.11
235_G416_A0.6040.11
27_F88_V0.6030.11
515_R564_L0.6020.11
14_R611_L0.6020.11
177_A318_G0.6020.11
495_K601_I0.6010.11
204_Q214_F0.6010.11
34_T154_V0.6010.11
14_R536_L0.6010.11
567_G572_Q0.6000.11
277_G281_V0.6000.11
107_G307_T0.6000.11
476_E570_F0.6000.11
102_I295_A0.5980.11
119_D512_E0.5970.11
13_G17_S0.5960.11
270_I326_S0.5960.11
562_R587_A0.5960.11
62_L402_I0.5950.11
526_Y610_A0.5950.11
52_V120_G0.5950.11
74_G344_D0.5940.11
118_V575_E0.5920.11
541_L579_F0.5910.11
218_E262_Y0.5900.11
232_M247_A0.5890.11
43_L108_G0.5880.11
37_F41_G0.5880.11
214_F587_A0.5880.11
42_W264_L0.5870.11
25_G82_A0.5860.11
33_I313_F0.5860.11
94_M122_I0.5850.11
552_V586_I0.5850.11
68_G221_P0.5840.11
20_V296_S0.5840.11
215_F333_L0.5830.11
167_F311_A0.5800.11
316_I631_E0.5790.11
463_E628_E0.5790.11
72_V156_A0.5770.11
502_F571_C0.5760.11
66_Y351_R0.5750.11
513_A628_E0.5740.11
138_I564_L0.5740.11
114_F526_Y0.5740.11
92_A149_G0.5740.11
247_A334_L0.5730.11
51_L438_M0.5730.11
118_V524_G0.5730.11
516_F573_Y0.5730.11
346_E565_K0.5730.11
529_P627_D0.5710.11
377_V468_A0.5710.11
624_T628_E0.5690.11
65_G151_G0.5680.11
172_D570_F0.5670.11
53_G62_L0.5670.11
573_Y611_L0.5670.11
580_G586_I0.5650.11
523_K530_E0.5630.10
541_L621_A0.5630.10
38_I272_A0.5630.10
520_Q595_A0.5620.10
166_N459_T0.5620.10
339_V562_R0.5620.10
103_A595_A0.5620.10
57_T120_G0.5620.10
310_G317_A0.5600.10
103_A106_L0.5600.10
548_E578_R0.5590.10
354_D447_I0.5590.10
18_N566_T0.5570.10
24_I256_H0.5570.10
546_L612_D0.5570.10
352_M360_K0.5560.10
570_F596_R0.5560.10
34_T49_A0.5560.10
135_A348_A0.5560.10
51_L597_N0.5550.10
415_S620_L0.5540.10
217_I450_T0.5540.10
51_L324_A0.5540.10
14_R441_V0.5540.10
20_V597_N0.5520.10
466_V570_F0.5520.10
66_Y78_G0.5510.10
109_W301_L0.5510.10
361_G570_F0.5510.10
27_F60_L0.5500.10
172_D603_V0.5490.10
281_V356_K0.5490.10
414_N448_S0.5490.10
582_E603_V0.5480.10
18_N603_V0.5470.10
39_P289_G0.5470.10
450_T548_E0.5450.10
449_L595_A0.5440.10
92_A542_T0.5440.10
507_A590_V0.5420.10
463_E467_A0.5410.10
15_F68_G0.5400.10
40_T288_G0.5390.10
251_F327_F0.5390.10
108_G566_T0.5390.10
122_I443_Q0.5390.10
84_T601_I0.5390.10
280_G401_K0.5380.10
552_V601_I0.5380.10
283_T603_V0.5380.10
295_A556_T0.5380.10
443_Q508_A0.5380.10
567_G587_A0.5370.10
25_G151_G0.5370.10
595_A609_N0.5370.10
95_P187_L0.5360.10
612_D623_T0.5340.10
11_S604_I0.5340.10
333_L558_E0.5340.10
541_L605_T0.5330.10
218_E221_P0.5330.10
235_G398_L0.5330.10
546_L586_I0.5330.10
34_T59_L0.5330.10
522_V562_R0.5320.10
505_R612_D0.5310.10
44_P566_T0.5300.10
486_F626_V0.5290.10
347_A591_I0.5290.10
293_S378_R0.5280.10
522_V612_D0.5270.10
332_I462_T0.5270.10
558_E632_L0.5270.10
160_M320_C0.5270.10
116_R470_R0.5260.10
562_R613_D0.5250.10
619_R631_E0.5250.10
114_F335_K0.5240.10
304_L582_E0.5240.10
529_P596_R0.5230.10
40_T164_G0.5220.10
348_A352_M0.5210.10
521_L538_R0.5210.10
309_K580_G0.5200.10
503_L618_E0.5200.10
224_G444_A0.5190.10
489_S528_E0.5190.10
250_H380_I0.5190.10
268_R595_A0.5170.10
616_V633_L0.5170.10
329_V513_A0.5170.10
46_E208_E0.5160.10
403_Q605_T0.5160.10
346_E619_R0.5160.10
108_G380_I0.5160.10
16_L230_A0.5160.10
88_V558_E0.5150.10
597_N603_V0.5150.10
275_L334_L0.5140.10
275_L542_T0.5140.10
121_K401_K0.5140.10
162_A591_I0.5130.10
53_G170_V0.5130.10
182_E250_H0.5130.10
20_V233_F0.5120.10
303_V628_E0.5120.10
294_P352_M0.5110.10
183_P388_M0.5100.10
224_G253_G0.5090.10
126_F195_H0.5090.10
507_A580_G0.5080.10
520_Q611_L0.5080.10
54_P88_V0.5080.10
370_V492_N0.5060.10
338_K416_A0.5060.10
314_A321_A0.5060.10
19_M134_S0.5050.10
484_D627_D0.5050.10
549_S587_A0.5040.10
153_I540_K0.5040.10
411_S523_K0.5040.10
435_E438_M0.5020.10
557_V597_N0.5010.10
227_V570_F0.5010.10
263_V270_I0.5010.10
256_H444_A0.5000.10
294_P546_L0.5000.10
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1a3aA 2 0.2292 100 0.872 Contact Map
3qnqA 2 0.551 100 0.874 Contact Map
3oxpA 2 0.2276 100 0.884 Contact Map
1a6jA 4 0.2402 100 0.884 Contact Map
3bjvA 2 0.2276 100 0.884 Contact Map
2oq3A 1 0.2261 100 0.884 Contact Map
2oqtA 2 0.2292 100 0.885 Contact Map
4m62S 1 0.2292 100 0.887 Contact Map
2a0jA 1 0.2229 100 0.888 Contact Map
3urrA 2 0.2308 100 0.889 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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