DHE4 - ECOLI - GREMLIN Contacts

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DHE4 - NADP-specific glutamate dehydrogenase

UniProt:	P00370	Sequences: MDQTYSLESFLNHVQKRDPNQTEFAQAVREVMTTLWPFLEQNPKYRQMSLLERLVEPERVIQFRVVWVDDRNQIQVNRAWRVQFSSAIGPYKGGMRFHPSVNLSILKFLGFEQTFKNALTTLPMGGGKGGSDFDPKGKSEGEVMRFCQALMTELYRHLGADTDVPAGDIGVGGREVGFMAGMMKKLSNNTACVFTGKGLSFGGSLIRPEATGYGLVYFTEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTKEKLARLIEIKASRDGRVADYAKEFGLVYLEGQQPWSLPVDIALPCATQNELDVDAAHQLIANGVKAVAEGANMPTTIEATELFQQAGVLFAPGKAANAGGVATSGLEMAQNAARLGWKAEKVDARLHHIMLDIHHACVEHGGEGEQTNYVQGANIAGFVKVADAMLAQGVI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10372
Length:	447 (403)
Sequences:	4726 (2276)
Seq/√Len:	113.4

ECOLI - DHE4
BACSU - DHE2 GUDB DHLE
HALSA - DHEB DHE4 DHE
SULSO - Q97X22 DHE2 Q97Y81 Q97WS2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
251_A	256_A	4.439	1.00
236_S	315_V	3.641	1.00
336_I	358_L	3.352	1.00
58_E	86_S	3.243	1.00
219_T	344_A	3.222	1.00
237_V	248_I	2.926	1.00
275_T	278_K	2.924	1.00
124_M	381_G	2.917	1.00
312_S	334_Q	2.749	1.00
281_R	289_R	2.743	1.00
248_I	261_A	2.685	1.00
228_M	233_M	2.653	1.00
359_F	364_V	2.620	1.00
141_G	145_R	2.580	1.00
221_A	224_K	2.573	1.00
360_Q	424_N	2.463	1.00
234_R	255_G	2.449	1.00
357_E	361_Q	2.412	1.00
221_A	407_L	2.408	1.00
152_T	182_M	2.336	1.00
327_L	351_T	2.331	1.00
234_R	257_R	2.322	1.00
62_Q	103_L	2.316	1.00
69_D	75_Q	2.291	1.00
217_Y	220_E	2.261	1.00
235_V	256_A	2.258	1.00
225_R	414_V	2.234	1.00
235_V	251_A	2.192	1.00
206_I	395_A	2.172	1.00
84_F	110_G	2.167	1.00
260_T	310_P	2.162	1.00
220_E	403_H	2.146	1.00
66_V	149_A	2.141	1.00
329_V	354_E	2.137	1.00
410_H	414_V	2.129	1.00
172_G	175_E	2.126	1.00
134_D	137_G	2.116	1.00
397_K	401_R	2.026	1.00
200_S	439_D	2.020	1.00
351_T	359_F	2.003	1.00
424_N	427_Q	1.990	1.00
133_F	138_K	1.944	1.00
314_P	336_I	1.919	1.00
225_R	410_H	1.901	1.00
95_M	179_M	1.873	1.00
306_E	309_Q	1.865	1.00
230_F	256_A	1.853	1.00
152_T	186_L	1.835	1.00
215_L	346_G	1.815	1.00
221_A	411_H	1.814	1.00
320_P	347_A	1.780	1.00
229_G	232_G	1.780	1.00
169_I	323_T	1.778	1.00
260_T	313_L	1.765	1.00
332_A	358_L	1.764	1.00
151_M	179_M	1.764	1.00
155_Y	187_S	1.740	1.00
70_D	139_S	1.737	1.00
271_E	303_V	1.732	1.00
79_A	150_L	1.729	1.00
249_E	253_E	1.725	1.00
152_T	185_K	1.672	1.00
236_S	260_T	1.670	1.00
418_G	422_Q	1.656	1.00
133_F	146_F	1.655	1.00
102_N	105_I	1.651	1.00
278_K	281_R	1.648	1.00
37_P	40_E	1.645	1.00
39_L	43_P	1.630	1.00
403_H	407_L	1.615	1.00
344_A	372_A	1.608	1.00
327_L	335_L	1.585	1.00
276_K	280_A	1.564	1.00
217_Y	399_D	1.548	1.00
136_K	139_S	1.548	1.00
265_S	292_R	1.540	1.00
411_H	415_E	1.540	1.00
328_D	331_A	1.539	1.00
267_T	305_L	1.533	1.00
215_L	344_A	1.531	1.00
367_A	372_A	1.520	1.00
49_S	73_Q	1.509	1.00
235_V	319_L	1.501	1.00
344_A	367_A	1.498	1.00
60_V	107_K	1.498	1.00
261_A	279_L	1.496	1.00
173_G	208_P	1.495	1.00
144_M	148_Q	1.492	1.00
182_M	185_K	1.486	1.00
347_A	350_P	1.482	1.00
358_L	362_A	1.481	1.00
274_F	279_L	1.479	1.00
278_K	296_Y	1.463	1.00
247_A	321_C	1.458	1.00
329_V	358_L	1.436	1.00
435_V	439_D	1.435	1.00
82_V	110_G	1.431	1.00
68_V	141_G	1.425	1.00
249_E	280_A	1.421	1.00
155_Y	186_L	1.420	1.00
140_E	174_R	1.413	1.00
148_Q	182_M	1.412	1.00
259_I	315_V	1.411	1.00
38_F	42_N	1.406	1.00
42_N	45_Y	1.401	1.00
394_K	397_K	1.400	1.00
421_E	427_Q	1.394	1.00
243_V	346_G	1.394	1.00
228_M	341_K	1.391	1.00
86_S	91_Y	1.376	1.00
95_M	150_L	1.352	1.00
220_E	224_K	1.347	1.00
251_A	258_V	1.334	1.00
139_S	142_E	1.331	1.00
333_H	358_L	1.317	1.00
410_H	425_Y	1.316	1.00
225_R	418_G	1.315	1.00
48_M	442_L	1.312	1.00
216_V	251_A	1.310	1.00
88_I	121_T	1.307	1.00
267_T	307_G	1.301	0.99
259_I	269_V	1.299	0.99
294_A	298_K	1.299	0.99
60_V	103_L	1.296	0.99
200_S	443_A	1.294	0.99
264_S	283_I	1.286	0.99
236_S	259_I	1.281	0.99
247_A	319_L	1.274	0.99
56_E	78_R	1.269	0.99
237_V	256_A	1.263	0.99
327_L	359_F	1.261	0.99
222_M	367_A	1.257	0.99
387_N	392_G	1.254	0.99
329_V	333_H	1.254	0.99
394_K	404_H	1.239	0.99
65_V	149_A	1.235	0.99
304_Y	307_G	1.235	0.99
45_Y	439_D	1.233	0.99
80_W	132_D	1.228	0.99
39_L	42_N	1.227	0.99
138_K	146_F	1.225	0.99
219_T	317_I	1.225	0.99
149_A	152_T	1.222	0.99
114_T	437_V	1.221	0.99
278_K	300_F	1.213	0.99
235_V	258_V	1.209	0.99
414_V	418_G	1.205	0.99
270_D	296_Y	1.199	0.99
234_R	316_D	1.198	0.99
423_T	431_I	1.198	0.99
97_F	171_V	1.197	0.99
215_L	319_L	1.180	0.99
37_P	41_Q	1.180	0.99
82_V	103_L	1.179	0.99
235_V	317_I	1.174	0.99
63_F	154_L	1.170	0.99
236_S	313_L	1.161	0.99
149_A	153_E	1.157	0.99
208_P	246_Y	1.148	0.99
85_S	441_M	1.146	0.99
234_R	271_E	1.146	0.99
115_F	437_V	1.146	0.99
220_E	254_F	1.139	0.99
35_L	38_F	1.132	0.99
225_R	411_H	1.132	0.99
252_M	277_E	1.130	0.99
215_L	321_C	1.130	0.99
226_H	365_L	1.128	0.99
282_L	290_D	1.127	0.99
378_A	382_L	1.125	0.99
41_Q	44_K	1.121	0.98
291_G	295_D	1.121	0.98
40_E	44_K	1.111	0.98
215_L	219_T	1.111	0.98
279_L	282_L	1.108	0.98
220_E	230_F	1.105	0.98
217_Y	403_H	1.102	0.98
356_T	360_Q	1.098	0.98
252_M	276_K	1.098	0.98
257_R	272_S	1.096	0.98
351_T	355_A	1.094	0.98
270_D	278_K	1.093	0.98
279_L	283_I	1.088	0.98
38_F	41_Q	1.085	0.98
308_Q	311_W	1.081	0.98
219_T	319_L	1.080	0.98
162_T	188_N	1.074	0.98
416_H	432_A	1.072	0.98
282_L	296_Y	1.072	0.98
282_L	291_G	1.068	0.98
222_M	344_A	1.061	0.98
318_A	335_L	1.060	0.98
120_T	374_A	1.058	0.98
52_E	55_V	1.054	0.98
278_K	282_L	1.051	0.98
245_Q	280_A	1.049	0.98
439_D	442_L	1.048	0.98
40_E	43_P	1.046	0.98
319_L	344_A	1.045	0.98
139_S	143_V	1.043	0.98
356_T	426_V	1.043	0.98
104_S	107_K	1.037	0.97
115_F	370_K	1.036	0.97
399_D	403_H	1.035	0.97
179_M	182_M	1.032	0.97
182_M	186_L	1.028	0.97
97_F	147_C	1.026	0.97
35_L	39_L	1.026	0.97
263_D	292_R	1.024	0.97
37_P	42_N	1.023	0.97
61_I	157_H	1.022	0.97
415_E	420_G	1.020	0.97
408_D	412_A	1.019	0.97
342_A	365_L	1.012	0.97
40_E	45_Y	0.997	0.97
91_Y	127_G	0.996	0.97
371_A	413_C	0.995	0.97
420_G	423_T	0.989	0.97
213_Y	249_E	0.985	0.97
63_F	79_A	0.980	0.96
99_P	134_D	0.977	0.96
140_E	143_V	0.976	0.96
288_S	291_G	0.976	0.96
266_G	294_A	0.974	0.96
144_M	179_M	0.973	0.96
98_H	323_T	0.971	0.96
201_F	443_A	0.967	0.96
100_S	105_I	0.961	0.96
120_T	378_A	0.961	0.96
78_R	132_D	0.955	0.96
66_V	76_V	0.954	0.96
336_I	362_A	0.953	0.96
147_C	151_M	0.952	0.96
416_H	431_I	0.951	0.96
415_E	418_G	0.946	0.96
416_H	421_E	0.946	0.96
297_A	302_L	0.939	0.95
180_A	190_T	0.939	0.95
136_K	143_V	0.938	0.95
149_A	185_K	0.936	0.95
268_V	293_V	0.936	0.95
154_L	157_H	0.933	0.95
251_A	319_L	0.924	0.95
290_D	293_V	0.923	0.95
333_H	337_A	0.919	0.95
290_D	295_D	0.916	0.95
218_F	413_C	0.914	0.95
421_E	424_N	0.914	0.95
378_A	406_M	0.913	0.95
49_S	52_E	0.912	0.95
282_L	295_D	0.910	0.95
128_K	348_N	0.910	0.95
309_Q	312_S	0.908	0.95
308_Q	312_S	0.908	0.95
215_L	247_A	0.906	0.95
52_E	75_Q	0.905	0.94
88_I	125_G	0.901	0.94
311_W	318_A	0.899	0.94
404_H	408_D	0.898	0.94
434_F	437_V	0.898	0.94
75_Q	137_G	0.897	0.94
38_F	44_K	0.897	0.94
269_V	313_L	0.896	0.94
60_V	82_V	0.895	0.94
337_A	352_T	0.893	0.94
400_A	403_H	0.891	0.94
37_P	45_Y	0.890	0.94
257_R	275_T	0.890	0.94
136_K	140_E	0.888	0.94
343_V	355_A	0.882	0.94
247_A	251_A	0.878	0.94
153_E	156_R	0.877	0.94
216_V	254_F	0.874	0.93
136_K	264_S	0.872	0.93
68_V	75_Q	0.869	0.93
252_M	275_T	0.865	0.93
351_T	366_F	0.865	0.93
38_F	43_P	0.864	0.93
400_A	404_H	0.864	0.93
374_A	378_A	0.862	0.93
269_V	303_V	0.859	0.93
416_H	435_V	0.856	0.93
40_E	46_R	0.852	0.93
62_Q	78_R	0.851	0.92
60_V	106_L	0.850	0.92
213_Y	399_D	0.849	0.92
69_D	77_N	0.847	0.92
327_L	369_G	0.847	0.92
292_R	295_D	0.846	0.92
346_G	372_A	0.845	0.92
79_A	142_E	0.843	0.92
226_H	341_K	0.840	0.92
263_D	266_G	0.838	0.92
218_F	372_A	0.836	0.92
319_L	346_G	0.834	0.92
244_A	263_D	0.833	0.92
50_L	442_L	0.832	0.92
391_L	397_K	0.831	0.92
273_G	282_L	0.831	0.92
391_L	394_K	0.831	0.92
234_R	314_P	0.830	0.92
151_M	194_F	0.828	0.91
54_L	115_F	0.826	0.91
407_L	411_H	0.822	0.91
359_F	366_F	0.821	0.91
321_C	346_G	0.817	0.91
316_D	341_K	0.817	0.91
121_T	405_I	0.816	0.91
223_L	230_F	0.815	0.91
149_A	182_M	0.815	0.91
312_S	331_A	0.814	0.91
273_G	279_L	0.814	0.91
275_T	283_I	0.813	0.91
34_T	38_F	0.812	0.91
237_V	261_A	0.812	0.91
110_G	114_T	0.808	0.90
39_L	45_Y	0.804	0.90
282_L	297_A	0.802	0.90
328_D	352_T	0.800	0.90
213_Y	250_K	0.800	0.90
222_M	365_L	0.797	0.90
177_G	198_G	0.792	0.90
222_M	342_A	0.792	0.90
330_D	333_H	0.789	0.89
278_K	283_I	0.788	0.89
176_V	201_F	0.787	0.89
156_R	188_N	0.786	0.89
396_E	400_A	0.783	0.89
198_G	201_F	0.782	0.89
36_W	40_E	0.781	0.89
422_Q	427_Q	0.779	0.89
98_H	169_I	0.774	0.88
377_V	380_S	0.772	0.88
240_S	347_A	0.771	0.88
276_K	279_L	0.769	0.88
408_D	411_H	0.769	0.88
219_T	342_A	0.767	0.88
343_V	351_T	0.767	0.88
414_V	417_G	0.765	0.88
273_G	278_K	0.765	0.88
215_L	372_A	0.763	0.88
385_A	391_L	0.763	0.88
251_A	317_I	0.760	0.87
309_Q	331_A	0.754	0.87
248_I	279_L	0.751	0.87
138_K	143_V	0.747	0.87
223_L	342_A	0.743	0.86
300_F	305_L	0.740	0.86
279_L	296_Y	0.738	0.86
386_Q	393_W	0.738	0.86
240_S	276_K	0.736	0.86
267_T	312_S	0.736	0.86
84_F	114_T	0.734	0.86
70_D	145_R	0.731	0.85
273_G	281_R	0.731	0.85
246_Y	249_E	0.731	0.85
218_F	371_A	0.730	0.85
300_F	303_V	0.729	0.85
147_C	175_E	0.727	0.85
336_I	364_V	0.726	0.85
272_S	301_G	0.726	0.85
353_I	356_T	0.725	0.85
308_Q	330_D	0.722	0.85
366_F	369_G	0.721	0.85
275_T	279_L	0.721	0.85
88_I	118_A	0.721	0.85
174_R	177_G	0.719	0.84
223_L	317_I	0.718	0.84
250_K	399_D	0.716	0.84
61_I	154_L	0.716	0.84
97_F	131_S	0.715	0.84
160_A	190_T	0.714	0.84
39_L	46_R	0.713	0.84
209_E	246_Y	0.712	0.84
43_P	46_R	0.711	0.84
276_K	283_I	0.710	0.84
158_L	179_M	0.710	0.84
65_V	146_F	0.708	0.84
439_D	443_A	0.708	0.84
248_I	276_K	0.708	0.84
59_R	83_Q	0.705	0.83
160_A	189_N	0.703	0.83
39_L	44_K	0.701	0.83
38_F	45_Y	0.700	0.83
274_F	282_L	0.699	0.83
267_T	313_L	0.698	0.83
335_L	359_F	0.695	0.82
395_A	399_D	0.695	0.82
265_S	304_Y	0.694	0.82
116_K	348_N	0.691	0.82
106_L	110_G	0.682	0.81
195_T	380_S	0.681	0.81
230_F	235_V	0.679	0.81
62_Q	80_W	0.679	0.81
351_T	356_T	0.679	0.81
213_Y	411_H	0.678	0.81
261_A	293_V	0.676	0.81
166_A	377_V	0.675	0.81
366_F	426_V	0.674	0.80
121_T	408_D	0.674	0.80
409_I	413_C	0.673	0.80
67_W	77_N	0.673	0.80
268_V	279_L	0.670	0.80
75_Q	138_K	0.669	0.80
35_L	41_Q	0.669	0.80
343_V	359_F	0.668	0.80
34_T	39_L	0.668	0.80
170_G	243_V	0.667	0.80
254_F	279_L	0.667	0.80
249_E	277_E	0.666	0.80
161_D	388_A	0.666	0.80
260_T	267_T	0.665	0.80
135_P	143_V	0.661	0.79
314_P	337_A	0.661	0.79
356_T	359_F	0.657	0.79
357_E	360_Q	0.656	0.79
79_A	145_R	0.656	0.79
246_Y	250_K	0.656	0.79
417_G	423_T	0.654	0.78
138_K	142_E	0.653	0.78
95_M	165_P	0.653	0.78
184_K	444_Q	0.652	0.78
82_V	127_G	0.652	0.78
63_F	67_W	0.652	0.78
129_G	150_L	0.652	0.78
36_W	39_L	0.651	0.78
385_A	389_A	0.650	0.78
143_V	290_D	0.650	0.78
236_S	267_T	0.648	0.78
417_G	425_Y	0.646	0.78
160_A	191_A	0.643	0.77
306_E	310_P	0.639	0.77
112_E	349_M	0.639	0.77
281_R	288_S	0.636	0.76
328_D	334_Q	0.635	0.76
234_R	269_V	0.633	0.76
80_W	150_L	0.633	0.76
295_D	304_Y	0.632	0.76
243_V	264_S	0.632	0.76
88_I	436_K	0.632	0.76
328_D	351_T	0.629	0.76
240_S	320_P	0.628	0.76
416_H	423_T	0.628	0.76
422_Q	426_V	0.627	0.75
333_H	362_A	0.626	0.75
68_V	74_I	0.626	0.75
423_T	427_Q	0.626	0.75
379_T	398_V	0.625	0.75
212_G	247_A	0.625	0.75
148_Q	181_G	0.622	0.75
412_A	415_E	0.622	0.75
145_R	148_Q	0.620	0.75
185_K	192_C	0.619	0.75
250_K	256_A	0.618	0.74
69_D	89_G	0.618	0.74
122_L	437_V	0.617	0.74
211_T	242_N	0.617	0.74
212_G	243_V	0.615	0.74
42_N	46_R	0.615	0.74
80_W	149_A	0.615	0.74
45_Y	431_I	0.615	0.74
274_F	278_K	0.615	0.74
262_S	310_P	0.613	0.74
317_I	342_A	0.610	0.73
211_T	373_N	0.610	0.73
204_S	398_V	0.609	0.73
216_V	219_T	0.607	0.73
119_L	412_A	0.607	0.73
108_F	349_M	0.606	0.73
176_V	194_F	0.605	0.73
400_A	407_L	0.605	0.73
87_A	437_V	0.604	0.73
296_Y	302_L	0.604	0.73
433_G	437_V	0.602	0.73
229_G	233_M	0.602	0.73
221_A	225_R	0.602	0.73
34_T	37_P	0.602	0.73
225_R	365_L	0.601	0.72
124_M	384_M	0.599	0.72
365_L	425_Y	0.599	0.72
375_G	379_T	0.599	0.72
327_L	366_F	0.599	0.72
318_A	343_V	0.597	0.72
52_E	153_E	0.594	0.72
233_M	316_D	0.592	0.71
276_K	282_L	0.592	0.71
224_K	407_L	0.592	0.71
120_T	409_I	0.591	0.71
289_R	295_D	0.587	0.71
37_P	44_K	0.587	0.71
83_Q	162_T	0.587	0.71
302_L	306_E	0.584	0.70
360_Q	366_F	0.583	0.70
86_S	184_K	0.583	0.70
40_E	55_V	0.582	0.70
44_K	51_L	0.582	0.70
128_K	166_A	0.581	0.70
204_S	386_Q	0.581	0.70
45_Y	435_V	0.580	0.70
367_A	425_Y	0.580	0.70
323_T	326_E	0.580	0.70
247_A	346_G	0.578	0.69
198_G	443_A	0.576	0.69
327_L	343_V	0.576	0.69
226_H	342_A	0.574	0.69
277_E	280_A	0.572	0.69
43_P	51_L	0.571	0.69
270_D	301_G	0.570	0.68
133_F	139_S	0.569	0.68
267_T	310_P	0.569	0.68
412_A	416_H	0.567	0.68
331_A	358_L	0.566	0.68
302_L	305_L	0.564	0.68
271_E	297_A	0.563	0.67
83_Q	91_Y	0.561	0.67
153_E	187_S	0.561	0.67
121_T	412_A	0.560	0.67
434_F	438_A	0.559	0.67
118_A	433_G	0.559	0.67
128_K	211_T	0.559	0.67
266_G	307_G	0.558	0.67
137_G	140_E	0.558	0.67
307_G	310_P	0.558	0.67
303_V	306_E	0.557	0.67
378_A	405_I	0.557	0.67
237_V	251_A	0.556	0.67
343_V	364_V	0.556	0.67
335_L	343_V	0.556	0.67
228_M	342_A	0.555	0.66
147_C	179_M	0.554	0.66
363_G	422_Q	0.551	0.66
220_E	231_E	0.550	0.66
356_T	366_F	0.549	0.66
116_K	128_K	0.549	0.66
180_A	194_F	0.548	0.65
87_A	441_M	0.548	0.65
179_M	194_F	0.547	0.65
402_L	406_M	0.547	0.65
373_N	377_V	0.542	0.65
101_V	130_G	0.542	0.65
92_K	380_S	0.542	0.65
245_Q	276_K	0.541	0.64
180_A	184_K	0.541	0.64
320_P	327_L	0.540	0.64
216_V	250_K	0.540	0.64
128_K	373_N	0.539	0.64
297_A	301_G	0.538	0.64
79_A	149_A	0.537	0.64
111_F	115_F	0.536	0.64
80_W	133_F	0.536	0.64
206_I	379_T	0.536	0.64
261_A	282_L	0.536	0.64
200_S	440_A	0.536	0.64
270_D	274_F	0.536	0.64
417_G	421_E	0.534	0.63
270_D	302_L	0.532	0.63
69_D	73_Q	0.531	0.63
99_P	136_K	0.531	0.63
305_L	313_L	0.530	0.63
295_D	298_K	0.530	0.63
125_G	375_G	0.530	0.63
128_K	242_N	0.530	0.63
222_M	410_H	0.529	0.63
236_S	310_P	0.529	0.63
195_T	207_R	0.528	0.63
398_V	403_H	0.528	0.63
50_L	438_A	0.526	0.62
212_G	346_G	0.526	0.62
89_G	158_L	0.525	0.62
314_P	341_K	0.525	0.62
40_E	47_Q	0.525	0.62
220_E	407_L	0.524	0.62
411_H	414_V	0.522	0.62
291_G	294_A	0.522	0.62
410_H	413_C	0.521	0.62
380_S	383_E	0.520	0.61
92_K	207_R	0.520	0.61
161_D	390_R	0.520	0.61
145_R	152_T	0.518	0.61
327_L	331_A	0.517	0.61
423_T	428_G	0.517	0.61
248_I	252_M	0.516	0.61
68_V	144_M	0.513	0.60
213_Y	253_E	0.513	0.60
280_A	283_I	0.513	0.60
266_G	293_V	0.511	0.60
236_S	314_P	0.511	0.60
64_R	68_V	0.510	0.60
421_E	425_Y	0.509	0.60
157_H	162_T	0.509	0.60
435_V	442_L	0.507	0.59
273_G	283_I	0.507	0.59
183_M	187_S	0.507	0.59
290_D	294_A	0.506	0.59
117_N	377_V	0.506	0.59
151_M	183_M	0.506	0.59
230_F	233_M	0.506	0.59
240_S	293_V	0.505	0.59
170_G	212_G	0.505	0.59
312_S	335_L	0.505	0.59
150_L	401_R	0.504	0.59
106_L	130_G	0.501	0.59
246_Y	288_S	0.501	0.59
433_G	440_A	0.500	0.58

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3r3jA	5	0.9933	100	0.093	Contact Map
4fccA	5	0.9799	100	0.093	Contact Map
2bmaA	5	0.9933	100	0.096	Contact Map
1bgvA	5	0.9843	100	0.1	Contact Map
3mw9A	5	0.9396	100	0.139	Contact Map
4xgiA	6	0.9217	100	0.14	Contact Map
2yfqA	5	0.868	100	0.141	Contact Map
3aoeE	3	0.9284	100	0.144	Contact Map
2tmgA	5	0.9083	100	0.144	Contact Map
1v9lA	4	0.9195	100	0.155	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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