GREMLIN Database
FRDA - Fumarate reductase flavoprotein subunit
UniProt: P00363 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10330
Length: 602 (520)
Sequences: 5440 (2809)
Seq/√Len: 123.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
9_A171_L3.9001.00
268_G282_Y3.8701.00
365_D369_E3.8521.00
158_V216_M3.4141.00
84_D88_H3.3061.00
6_A34_A3.2651.00
261_Y266_D3.2151.00
78_C83_V3.1311.00
257_N261_Y3.0701.00
464_C520_A2.9841.00
86_F386_L2.9371.00
20_A190_V2.9021.00
470_P527_K2.8711.00
463_G475_K2.8511.00
484_Q517_E2.8391.00
257_N298_E2.6611.00
175_N178_E2.6281.00
470_P474_Q2.5921.00
244_M248_C2.5621.00
376_F410_Q2.5621.00
265_Q283_M2.5381.00
153_F184_I2.5131.00
477_I520_A2.4521.00
89_H406_L2.4301.00
11_V171_L2.4231.00
262_R284_E2.3981.00
143_T146_Q2.3531.00
527_K540_C2.3521.00
469_T536_L2.3491.00
218_L518_C2.3271.00
455_E479_K2.3271.00
34_A153_F2.3081.00
32_K151_Q2.3031.00
15_G400_L2.2921.00
481_A517_E2.2681.00
474_Q524_M2.2611.00
362_I381_C2.2391.00
5_Q185_R2.2221.00
20_A378_V2.1801.00
464_C476_T2.1331.00
24_A411_A2.1321.00
65_Y122_I2.1221.00
85_Y406_L2.1121.00
369_E410_Q2.1091.00
15_G46_T2.1031.00
469_T472_L2.0371.00
135_H138_H2.0341.00
214_M224_L2.0051.00
377_A381_C2.0051.00
223_P371_R2.0041.00
160_D219_S2.0041.00
36_I173_A1.9971.00
295_F313_V1.9911.00
191_M362_I1.9771.00
7_D187_N1.9731.00
256_V318_R1.9501.00
322_E326_H1.9391.00
256_V348_P1.9391.00
86_F403_F1.9301.00
480_L520_A1.9271.00
236_G354_T1.9261.00
24_A408_G1.9151.00
173_A184_I1.8691.00
464_C473_M1.8641.00
190_V411_A1.8591.00
318_R348_P1.8411.00
459_A476_T1.8361.00
333_C337_K1.8291.00
191_M381_C1.8091.00
34_A184_I1.7801.00
460_M464_C1.7671.00
370_T377_A1.7641.00
455_E486_R1.7561.00
196_A358_T1.7271.00
477_I517_E1.7271.00
248_C253_G1.7191.00
46_T137_L1.7181.00
254_I262_R1.7151.00
75_D543_R1.7091.00
80_Q84_D1.6991.00
175_N182_V1.6901.00
477_I521_H1.6891.00
217_A362_I1.6761.00
93_E96_Q1.6701.00
199_V519_M1.6611.00
219_S511_H1.6611.00
166_G373_K1.6611.00
107_R111_S1.6601.00
297_H301_K1.6571.00
326_H333_C1.6371.00
224_L227_M1.6361.00
67_F84_D1.6341.00
193_T213_G1.6311.00
25_A147_F1.6271.00
167_H374_G1.6161.00
168_V189_V1.6101.00
459_A479_K1.6051.00
74_G78_C1.5991.00
367_N410_Q1.5991.00
56_V63_F1.5891.00
456_M480_L1.5761.00
470_P535_R1.5721.00
82_V366_Q1.5711.00
217_A222_V1.5671.00
447_E486_R1.5441.00
368_C407_A1.5371.00
408_G412_T1.5331.00
223_P363_E1.5251.00
317_L320_L1.5221.00
364_T382_S1.5161.00
463_G476_T1.5081.00
326_H345_V1.5061.00
407_A411_A1.4941.00
8_L24_A1.4941.00
322_E345_V1.4901.00
298_E303_N1.4811.00
38_K508_E1.4801.00
479_K482_E1.4731.00
162_L183_Q1.4701.00
43_R48_A1.4531.00
144_S152_R1.4501.00
484_Q514_N1.4481.00
23_A409_E1.4471.00
63_F67_F1.4471.00
38_K212_D1.4391.00
476_T520_A1.4371.00
186_A189_V1.4311.00
82_V86_F1.4301.00
477_I524_M1.4291.00
167_H373_K1.4271.00
204_T236_G1.4241.00
95_T99_L1.4241.00
63_F88_H1.4201.00
6_A32_K1.4191.00
188_A414_R1.4151.00
67_F71_V1.4131.00
200_Y464_C1.4071.00
38_K210_T1.4041.00
89_H92_T1.4011.00
359_M532_A1.3911.00
98_E112_V1.3901.00
463_G472_L1.3861.00
93_E405_R1.3831.00
161_I168_V1.3771.00
410_Q414_R1.3771.00
53_S136_M1.3741.00
293_Q534_Q1.3641.00
6_A151_Q1.3621.00
517_E521_H1.3611.00
190_V378_V1.3601.00
102_C136_M1.3591.00
46_T400_L1.3571.00
26_Q147_F1.3551.00
470_P524_M1.3511.00
191_M375_L1.3501.00
333_C345_V1.3491.00
245_T248_C1.3411.00
6_A9_A1.3401.00
408_G411_A1.3361.00
11_V191_M1.3341.00
197_G355_A1.3251.00
212_D511_H1.3211.00
153_F156_H1.3111.00
225_R363_E1.3071.00
201_R458_L1.3061.00
6_A153_F1.3051.00
8_L190_V1.3041.00
191_M217_A1.3031.00
196_A230_V1.2951.00
464_C519_M1.2901.00
225_R383_S1.2861.00
245_T332_I1.2821.00
18_L144_S1.2801.00
54_A394_S1.2791.00
458_L462_E1.2681.00
263_Y267_Y1.2661.00
296_W300_R1.2631.00
13_A37_S1.2611.00
474_Q478_D1.2551.00
158_V171_L1.2470.99
156_H173_A1.2400.99
156_H175_N1.2330.99
523_A533_H1.2330.99
410_Q413_E1.2290.99
36_I171_L1.2250.99
22_I144_S1.2170.99
16_A378_V1.2160.99
82_V386_L1.2160.99
35_L152_R1.2150.99
54_A120_M1.2130.99
255_L351_V1.2120.99
63_F87_V1.2110.99
228_E526_R1.2080.99
162_L172_V1.2060.99
158_V173_A1.2030.99
411_A415_A1.2000.99
320_L324_K1.1970.99
144_S150_I1.1970.99
145_L154_D1.1880.99
19_R23_A1.1840.99
89_H93_E1.1790.99
463_G479_K1.1780.99
545_D548_F1.1770.99
376_F414_R1.1770.99
254_I284_E1.1720.99
405_R409_E1.1710.99
262_R265_Q1.1710.99
251_E328_R1.1700.99
219_S514_N1.1700.99
64_E68_H1.1610.99
67_F87_V1.1550.99
66_H395_N1.1520.99
68_H72_A1.1490.99
321_G324_K1.1450.99
90_C398_A1.1400.99
156_H182_V1.1400.99
342_V347_E1.1370.99
470_P540_C1.1350.99
102_C135_H1.1340.99
214_M515_V1.1320.99
64_E84_D1.1290.99
196_A519_M1.1280.99
35_L144_S1.1260.99
9_A36_I1.1260.99
160_D216_M1.1220.99
404_G408_G1.1200.99
487_F513_L1.1150.99
120_M394_S1.1130.99
436_R510_G1.1080.99
474_Q477_I1.0900.99
343_D346_K1.0890.99
85_Y366_Q1.0880.99
323_K327_E1.0870.99
125_T394_S1.0840.99
263_Y266_D1.0830.99
222_V375_L1.0830.99
8_L411_A1.0830.99
475_K479_K1.0800.99
66_H70_T1.0790.99
23_A408_G1.0750.98
20_A407_A1.0750.98
454_D458_L1.0720.98
325_L333_C1.0690.98
364_T377_A1.0590.98
23_A405_R1.0590.98
214_M358_T1.0590.98
20_A411_A1.0570.98
453_R457_G1.0540.98
96_Q405_R1.0520.98
18_L35_L1.0510.98
7_D32_K1.0510.98
85_Y89_H1.0490.98
322_E346_K1.0440.98
116_R123_E1.0440.98
134_F138_H1.0400.98
11_V158_V1.0400.98
85_Y403_F1.0380.98
102_C139_T1.0360.98
83_V87_V1.0300.98
459_A463_G1.0300.98
77_L530_R1.0260.98
143_T147_F1.0250.98
91_P95_T1.0150.98
188_A376_F1.0150.98
67_F80_Q1.0150.98
481_A521_H1.0130.98
164_D169_R1.0050.98
157_F507_I1.0030.98
522_S552_T0.9990.98
131_K331_F0.9980.98
172_V181_L0.9960.98
456_M509_L0.9950.98
112_V126_W0.9950.98
431_A435_Q0.9880.97
302_G310_G0.9850.97
172_V183_Q0.9840.97
362_I377_A0.9830.97
161_I171_L0.9820.97
453_R512_G0.9810.97
546_V549_L0.9780.97
41_P141_F0.9760.97
527_K548_F0.9750.97
266_D298_E0.9750.97
334_E338_A0.9740.97
467_Y536_L0.9690.97
386_L403_F0.9680.97
369_E414_R0.9670.97
105_S127_F0.9610.97
314_Y348_P0.9580.97
298_E301_K0.9530.97
161_I189_V0.9490.97
97_L136_M0.9440.97
9_A186_A0.9400.96
100_W143_T0.9390.96
378_V407_A0.9390.96
286_G290_K0.9370.96
188_A415_A0.9360.96
65_Y121_K0.9360.96
468_R523_A0.9340.96
103_P135_H0.9280.96
222_V371_R0.9270.96
459_A483_L0.9220.96
325_L345_V0.9210.96
23_A26_Q0.9180.96
248_C317_L0.9180.96
364_T403_F0.9160.96
254_I319_H0.9150.96
227_M519_M0.9140.96
364_T384_V0.9140.96
266_D301_K0.9100.96
412_T415_A0.9090.96
120_M125_T0.9070.96
267_Y294_A0.9070.96
157_F508_E0.9050.96
263_Y268_G0.9050.96
222_V372_I0.9040.96
163_V168_V0.9030.96
211_G515_V0.9010.96
70_T395_N0.9010.96
265_Q284_E0.9010.96
22_I100_W0.8990.95
21_A150_I0.8990.95
317_L325_L0.8980.95
215_G515_V0.8970.95
57_A126_W0.8960.95
19_R93_E0.8950.95
264_L267_Y0.8940.95
47_V134_F0.8940.95
326_H337_K0.8910.95
81_D366_Q0.8850.95
256_V316_D0.8850.95
25_A33_I0.8830.95
201_R461_E0.8780.95
286_G291_V0.8770.95
453_R509_L0.8770.95
265_Q268_G0.8770.95
92_T95_T0.8750.95
479_K483_L0.8720.95
23_A96_Q0.8710.95
86_F398_A0.8680.95
477_I481_A0.8640.94
142_Q146_Q0.8630.94
192_A378_V0.8620.94
53_S94_M0.8610.94
96_Q100_W0.8610.94
456_M513_L0.8590.94
336_A344_P0.8580.94
267_Y298_E0.8570.94
262_R283_M0.8550.94
473_M520_A0.8540.94
480_L517_E0.8530.94
223_P555_F0.8530.94
141_F152_R0.8520.94
22_I147_F0.8510.94
210_T508_E0.8480.94
215_G219_S0.8480.94
267_Y297_H0.8470.94
119_G359_M0.8460.94
115_R251_E0.8460.94
187_N415_A0.8390.93
39_V208_I0.8370.93
25_A149_Q0.8330.93
9_A34_A0.8320.93
8_L31_A0.8310.93
456_M483_L0.8300.93
260_G268_G0.8290.93
335_L338_A0.8290.93
82_V85_Y0.8280.93
258_K310_G0.8280.93
123_E251_E0.8280.93
414_R418_A0.8260.93
67_F83_V0.8260.93
452_I509_L0.8260.93
336_A342_V0.8250.93
230_V519_M0.8250.93
71_V83_V0.8240.93
433_V436_R0.8210.93
263_Y269_M0.8200.93
10_I33_I0.8200.93
163_V166_G0.8180.93
460_M516_A0.8150.92
227_M515_V0.8130.92
87_V90_C0.8110.92
521_H525_A0.8070.92
53_S398_A0.8070.92
264_L283_M0.8040.92
342_V349_I0.8030.92
164_D167_H0.8030.92
8_L28_N0.8020.92
223_P553_L0.8010.92
216_M219_S0.8000.92
188_A411_A0.7990.92
9_A189_V0.7970.92
106_R112_V0.7970.92
367_N406_L0.7960.92
299_W312_V0.7950.92
264_L268_G0.7940.91
227_M522_S0.7920.91
451_K455_E0.7920.91
467_Y534_Q0.7880.91
300_R536_L0.7880.91
137_L141_F0.7860.91
253_G317_L0.7860.91
428_A431_A0.7850.91
430_A433_V0.7840.91
118_G282_Y0.7810.91
22_I143_T0.7810.91
333_C344_P0.7810.91
71_V78_C0.7800.91
484_Q513_L0.7760.91
103_P139_T0.7760.91
89_H405_R0.7750.90
297_H467_Y0.7740.90
68_H80_Q0.7730.90
408_G415_A0.7730.90
128_A135_H0.7710.90
218_L556_R0.7710.90
411_A414_R0.7710.90
198_R457_G0.7700.90
200_Y519_M0.7700.90
300_R462_E0.7700.90
187_N419_G0.7620.90
263_Y284_E0.7600.90
45_H209_V0.7590.90
27_A413_E0.7590.90
25_A150_I0.7570.89
5_Q32_K0.7550.89
294_A298_E0.7470.89
409_E413_E0.7420.88
163_V169_R0.7410.88
246_E249_R0.7390.88
71_V80_Q0.7380.88
175_N180_T0.7380.88
244_M349_I0.7360.88
257_N263_Y0.7360.88
24_A28_N0.7350.88
55_A94_M0.7350.88
115_R127_F0.7340.88
263_Y295_F0.7320.88
336_A349_I0.7310.88
190_V407_A0.7300.88
79_E383_S0.7290.88
20_A24_A0.7290.88
249_R252_G0.7280.87
63_F91_P0.7270.87
166_G372_I0.7270.87
471_E475_K0.7260.87
226_D551_H0.7250.87
56_V87_V0.7240.87
364_T368_C0.7240.87
481_A485_E0.7230.87
199_V515_V0.7230.87
96_Q99_L0.7230.87
34_A151_Q0.7230.87
39_V43_R0.7230.87
369_E376_F0.7210.87
35_L41_P0.7210.87
41_P152_R0.7200.87
229_F526_R0.7200.87
9_A184_I0.7200.87
24_A31_A0.7200.87
447_E451_K0.7190.87
197_G203_N0.7180.87
434_E438_K0.7160.87
117_F125_T0.7150.87
413_E417_T0.7140.86
224_L518_C0.7140.86
233_H246_E0.7130.86
198_R512_G0.7080.86
103_P106_R0.7080.86
378_V404_G0.7080.86
167_H414_R0.7070.86
187_N420_N0.7060.86
447_E455_E0.7050.86
337_K345_V0.7050.86
15_G140_L0.7040.86
268_G287_P0.7010.85
529_S534_Q0.7010.85
169_R185_R0.7000.85
463_G520_A0.6980.85
482_E486_R0.6980.85
45_H48_A0.6980.85
196_A214_M0.6960.85
449_W506_T0.6960.85
27_A412_T0.6960.85
230_V358_T0.6950.85
10_I190_V0.6950.85
47_V138_H0.6950.85
530_R541_T0.6940.85
256_V314_Y0.6940.85
204_T354_T0.6930.85
522_S554_A0.6920.85
471_E474_Q0.6910.85
215_G511_H0.6900.85
19_R96_Q0.6880.84
260_G267_Y0.6870.84
53_S401_V0.6860.84
483_L513_L0.6850.84
13_A35_L0.6850.84
41_P154_D0.6840.84
474_Q521_H0.6830.84
213_G381_C0.6820.84
159_L433_V0.6810.84
454_D457_G0.6800.84
289_D293_Q0.6800.84
98_E106_R0.6800.84
432_G435_Q0.6790.84
155_E177_M0.6780.84
156_H184_I0.6770.83
202_Y461_E0.6760.83
482_E485_E0.6760.83
462_E472_L0.6760.83
55_A126_W0.6750.83
248_C325_L0.6720.83
485_E488_K0.6710.83
188_A374_G0.6710.83
117_F394_S0.6690.83
261_Y298_E0.6690.83
530_R540_C0.6690.83
193_T381_C0.6690.83
6_A184_I0.6680.83
518_C554_A0.6680.83
113_N127_F0.6670.83
468_R533_H0.6650.82
168_V372_I0.6650.82
54_A87_V0.6640.82
92_T405_R0.6640.82
160_D220_H0.6640.82
32_K149_Q0.6630.82
10_I20_A0.6630.82
452_I455_E0.6630.82
173_A182_V0.6630.82
288_R292_S0.6620.82
428_A432_G0.6610.82
527_K547_N0.6600.82
380_E391_R0.6600.82
443_Q446_G0.6590.82
325_L344_P0.6570.82
36_I184_I0.6570.82
31_A412_T0.6570.82
141_F145_L0.6540.81
176_M504_L0.6530.81
257_N266_D0.6510.81
258_K302_G0.6500.81
296_W466_I0.6490.81
427_E431_A0.6490.81
159_L181_L0.6480.81
40_Y154_D0.6450.80
218_L514_N0.6450.80
475_K478_D0.6440.80
15_G401_V0.6440.80
187_N421_G0.6430.80
125_T393_G0.6400.80
25_A412_T0.6380.80
225_R384_V0.6370.80
93_E401_V0.6360.79
369_E373_K0.6360.79
296_W467_Y0.6360.79
45_H206_G0.6350.79
58_Q122_I0.6330.79
528_E541_T0.6320.79
160_D433_V0.6310.79
294_A297_H0.6300.79
244_M332_I0.6290.79
480_L513_L0.6280.79
98_E126_W0.6280.79
159_L174_M0.6280.79
215_G514_N0.6280.79
171_L186_A0.6280.79
243_L246_E0.6270.78
233_H249_R0.6260.78
190_V415_A0.6250.78
299_W352_R0.6250.78
7_D34_A0.6240.78
62_S65_Y0.6230.78
378_V400_L0.6230.78
114_V126_W0.6220.78
139_T143_T0.6220.78
426_I430_A0.6200.78
31_A415_A0.6160.77
356_H392_L0.6160.77
310_G313_V0.6140.77
296_W299_W0.6130.77
514_N517_E0.6130.77
103_P138_H0.6120.77
543_R546_V0.6120.77
263_Y298_E0.6110.77
159_L172_V0.6100.77
239_G340_V0.6100.77
357_Y360_G0.6080.76
138_H142_Q0.6080.76
320_L325_L0.6080.76
222_V370_T0.6080.76
197_G205_N0.6080.76
260_G263_Y0.6080.76
262_R267_Y0.6060.76
53_S56_V0.6050.76
196_A199_V0.6050.76
317_L321_G0.6000.75
548_F551_H0.6000.75
453_R508_E0.5980.75
210_T511_H0.5970.75
56_V66_H0.5970.75
54_A66_H0.5960.75
374_G414_R0.5950.75
455_E458_L0.5950.75
455_E482_E0.5950.75
450_A505_Y0.5950.75
353_P356_H0.5950.75
218_L224_L0.5940.75
65_Y68_H0.5930.75
52_G249_R0.5930.75
235_T249_R0.5930.75
54_A125_T0.5930.75
102_C401_V0.5920.74
63_F84_D0.5920.74
313_V351_V0.5920.74
27_A409_E0.5910.74
476_T479_K0.5890.74
183_Q430_A0.5890.74
171_L189_V0.5880.74
44_S137_L0.5880.74
343_D347_E0.5880.74
295_F351_V0.5880.74
472_L476_T0.5870.74
135_H139_T0.5860.74
19_R100_W0.5860.74
246_E250_G0.5850.74
77_L229_F0.5840.73
325_L329_L0.5840.73
48_A206_G0.5830.73
7_D31_A0.5830.73
258_K303_N0.5820.73
162_L185_R0.5810.73
161_I227_M0.5810.73
71_V76_W0.5800.73
508_E512_G0.5790.73
41_P44_S0.5790.73
473_M523_A0.5790.73
356_H359_M0.5780.73
197_G230_V0.5770.73
321_G345_V0.5770.73
199_V516_A0.5760.72
444_D491_R0.5760.72
402_V406_L0.5760.72
136_M401_V0.5750.72
161_I191_M0.5730.72
228_E522_S0.5730.72
82_V384_V0.5720.72
435_Q438_K0.5710.72
322_E343_D0.5710.72
452_I513_L0.5710.72
202_Y352_R0.5700.72
462_E475_K0.5690.72
107_R113_N0.5690.72
543_R549_L0.5680.71
162_L169_R0.5660.71
382_S403_F0.5660.71
258_K312_V0.5660.71
459_A480_L0.5650.71
354_T357_Y0.5630.71
10_I28_N0.5630.71
169_R373_K0.5620.71
248_C332_I0.5620.71
434_E437_L0.5610.70
77_L228_E0.5610.70
242_I332_I0.5610.70
421_G424_A0.5600.70
403_F406_L0.5590.70
324_K327_E0.5590.70
117_F120_M0.5590.70
87_V403_F0.5590.70
548_F552_T0.5570.70
117_F393_G0.5560.70
243_L249_R0.5560.70
296_W352_R0.5560.70
89_H402_V0.5560.70
452_I490_V0.5560.70
38_K512_G0.5540.70
260_G269_M0.5530.69
56_V67_F0.5520.69
84_D87_V0.5520.69
446_G491_R0.5510.69
264_L286_G0.5510.69
53_S104_W0.5510.69
67_F88_H0.5510.69
259_N303_N0.5490.69
442_N482_E0.5480.69
197_G358_T0.5480.69
302_G312_V0.5480.69
521_H524_M0.5480.69
52_G233_H0.5460.68
335_L340_V0.5460.68
26_Q99_L0.5450.68
59_D111_S0.5450.68
289_D292_S0.5440.68
115_R328_R0.5430.68
322_E325_L0.5430.68
261_Y265_Q0.5430.68
185_R421_G0.5420.68
23_A27_A0.5420.68
356_H360_G0.5420.68
20_A404_G0.5420.68
22_I150_I0.5410.68
542_E547_N0.5400.68
36_I153_F0.5400.68
287_P290_K0.5390.67
431_A434_E0.5390.67
460_M463_G0.5390.67
257_N262_R0.5390.67
255_L264_L0.5380.67
19_R404_G0.5380.67
527_K535_R0.5380.67
262_R268_G0.5370.67
100_W139_T0.5370.67
174_M179_G0.5370.67
26_Q96_Q0.5360.67
376_F411_A0.5360.67
478_D481_A0.5360.67
486_R489_R0.5350.67
212_D508_E0.5350.67
235_T246_E0.5350.67
430_A434_E0.5340.67
437_L440_L0.5330.67
429_Q432_G0.5330.67
244_M351_V0.5320.66
481_A484_Q0.5310.66
268_G290_K0.5310.66
95_T98_E0.5300.66
24_A412_T0.5300.66
435_Q439_D0.5290.66
169_R189_V0.5290.66
70_T83_V0.5290.66
366_Q403_F0.5290.66
50_E329_L0.5270.66
409_E412_T0.5270.66
282_Y290_K0.5250.65
23_A404_G0.5250.65
258_K314_Y0.5240.65
352_R461_E0.5240.65
414_R417_T0.5230.65
26_Q143_T0.5230.65
37_S154_D0.5230.65
68_H71_V0.5220.65
254_I283_M0.5210.65
285_L288_R0.5210.65
242_I335_L0.5210.65
525_A552_T0.5200.65
157_F511_H0.5200.65
290_K293_Q0.5200.65
131_K135_H0.5200.65
443_Q495_T0.5180.64
213_G220_H0.5170.64
547_N550_K0.5160.64
453_R456_M0.5160.64
424_A428_A0.5160.64
404_G411_A0.5140.64
58_Q65_Y0.5140.64
492_I506_T0.5140.64
244_M335_L0.5130.64
114_V394_S0.5120.64
51_G246_E0.5110.63
189_V216_M0.5100.63
83_V86_F0.5090.63
462_E479_K0.5090.63
60_H122_I0.5080.63
204_T355_A0.5080.63
52_G235_T0.5080.63
337_K343_D0.5060.63
228_E528_E0.5060.63
525_A550_K0.5050.62
163_V372_I0.5050.62
73_G287_P0.5050.62
472_L475_K0.5050.62
105_S205_N0.5040.62
43_R47_V0.5030.62
268_G286_G0.5030.62
288_R293_Q0.5020.62
128_A139_T0.5010.62
298_E302_G0.5000.62
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1kf6A 1 0.9585 100 0.271 Contact Map
2bs2A 2 0.9734 100 0.272 Contact Map
2h88A 2 0.9352 100 0.288 Contact Map
2wdqA 1 0.9319 100 0.304 Contact Map
1chuA 2 0.7724 100 0.393 Contact Map
3gyxA 2 0.907 100 0.398 Contact Map
2e5vA 1 0.7807 100 0.423 Contact Map
1jnrA 2 0.8887 100 0.429 Contact Map
4c3xA 4 0.6229 100 0.622 Contact Map
1y0pA 1 0.6645 100 0.673 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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