T0905_30-353_1_324 - CASP12 - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

T0905_30-353_1_324 - T0905_30-353 1-324

ID:	90	Sequences: SLLNDAEDYKQQAVFIPKQIDILWVIDNSGSMKTSQDNLAANFQSFISRFQQYNYDFHMAVTTTEAWEKQFNSASEKARIKDGAVLQTNPKIETHSGVFIMDKNTANLGDVFSTNAKQGTLGNGDERAFSSFKEALLEPQNAGFRRSEAFLAVIIVSDEEDFSSSSAAFNESYNNANLHTVQSYVDFLDGYVGSRNYSVSTITVPDDACKTSLSTDGFARKISTRLPELATLTAGVKGSLCSNFGSTLELISDSIIQLSSVFKLNREPQEDTIVITVNGVSVPNDAVNGWTYDASNLTITFHGSSVPAADANITIDFYPKSIKL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	324 (279)
Sequences:	437 (383)
Seq/√Len:	22.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
247_T	251_I	7.464	1.00
244_F	251_I	5.115	1.00
244_F	247_T	4.946	1.00
121_L	126_E	4.748	1.00
182_Q	186_D	4.329	1.00
291_T	302_H	4.126	1.00
24_W	154_I	3.893	1.00
279_G	315_I	3.386	1.00
132_F	153_V	2.679	0.99
35_S	202_I	2.509	0.98
21_D	151_L	2.455	0.98
161_D	225_R	2.326	0.97
21_D	149_A	2.301	0.97
226_L	233_T	2.277	0.97
305_S	308_A	2.267	0.97
155_I	199_V	2.208	0.96
201_T	230_A	2.196	0.96
153_V	191_Y	2.184	0.96
230_A	233_T	2.099	0.95
244_F	248_L	2.066	0.95
247_T	254_S	2.038	0.94
305_S	309_A	2.034	0.94
128_A	155_I	2.028	0.94
39_L	154_I	1.994	0.93
208_A	220_R	1.993	0.93
39_L	156_V	1.941	0.92
101_M	104_N	1.930	0.92
157_S	226_L	1.895	0.92
245_G	248_L	1.878	0.91
313_I	317_F	1.876	0.91
247_T	250_L	1.830	0.90
126_E	159_E	1.808	0.89
24_W	63_T	1.806	0.89
27_D	31_S	1.805	0.89
9_Y	317_F	1.748	0.88
223_S	226_L	1.731	0.87
248_L	264_L	1.730	0.87
22_I	288_N	1.717	0.87
286_A	291_T	1.714	0.87
268_P	275_I	1.705	0.86
21_D	146_R	1.651	0.85
32_M	158_D	1.649	0.84
43_F	47_I	1.635	0.84
63_T	111_V	1.600	0.83
36_Q	64_T	1.586	0.82
28_N	64_T	1.571	0.81
184_Y	187_F	1.566	0.81
284_N	291_T	1.557	0.81
23_L	153_V	1.526	0.79
305_S	319_P	1.506	0.79
59_M	64_T	1.505	0.78
26_I	39_L	1.472	0.77
247_T	252_S	1.465	0.77
129_F	161_D	1.452	0.76
230_A	234_A	1.451	0.76
228_E	232_L	1.444	0.75
293_D	300_T	1.443	0.75
52_Q	154_I	1.443	0.75
230_A	235_G	1.439	0.75
265_N	278_N	1.428	0.75
127_R	260_S	1.408	0.74
66_A	131_S	1.407	0.74
146_R	149_A	1.394	0.73
194_S	251_I	1.376	0.72
45_S	153_V	1.364	0.71
315_I	318_Y	1.363	0.71
60_A	153_V	1.352	0.70
19_Q	148_E	1.348	0.70
234_A	289_G	1.334	0.69
6_A	305_S	1.330	0.69
30_G	228_E	1.324	0.69
166_S	296_N	1.291	0.67
264_L	317_F	1.285	0.66
64_T	128_A	1.256	0.65
28_N	36_Q	1.250	0.64
65_E	161_D	1.250	0.64
128_A	226_L	1.248	0.64
248_L	251_I	1.225	0.63
25_V	135_A	1.222	0.62
84_A	273_I	1.221	0.62
20_I	57_F	1.219	0.62
314_T	318_Y	1.218	0.62
284_N	302_H	1.217	0.62
61_V	304_S	1.208	0.62
203_T	317_F	1.207	0.61
268_P	301_F	1.205	0.61
209_C	241_C	1.191	0.60
131_S	184_Y	1.179	0.60
29_S	157_S	1.175	0.59
25_V	146_R	1.173	0.59
128_A	159_E	1.165	0.59
6_A	9_Y	1.158	0.58
127_R	159_E	1.157	0.58
299_I	302_H	1.153	0.58
56_D	146_R	1.152	0.58
264_L	268_P	1.149	0.58
260_S	319_P	1.142	0.57
34_T	255_I	1.136	0.57
120_T	126_E	1.132	0.56
60_A	197_Y	1.132	0.56
84_A	100_I	1.129	0.56
42_N	146_R	1.125	0.56
184_Y	296_N	1.124	0.56
191_Y	277_V	1.117	0.55
101_M	108_L	1.117	0.55
288_N	302_H	1.107	0.55
43_F	46_F	1.107	0.55
180_T	269_Q	1.107	0.55
251_I	254_S	1.105	0.55
301_F	317_F	1.082	0.53
227_P	230_A	1.082	0.53
16_I	186_D	1.078	0.53
46_F	59_M	1.078	0.53
235_G	239_S	1.077	0.53
22_I	152_A	1.074	0.52
148_E	252_S	1.073	0.52
29_S	204_V	1.066	0.52
58_H	141_N	1.065	0.52
129_F	225_R	1.065	0.52
25_V	28_N	1.063	0.52
21_D	301_F	1.050	0.51
152_A	197_Y	1.046	0.51
285_D	288_N	1.036	0.50
24_W	59_M	1.031	0.49
198_S	202_I	1.029	0.49
208_A	289_G	1.017	0.48
37_D	106_A	1.011	0.48
25_V	62_T	1.006	0.48
244_F	252_S	1.006	0.48
274_V	281_S	1.005	0.48
238_G	249_E	1.002	0.47
15_F	254_S	0.999	0.47
26_I	160_E	0.998	0.47
23_L	151_L	0.992	0.47
84_A	134_E	0.979	0.46
50_F	62_T	0.979	0.46
135_A	153_V	0.977	0.46
247_T	253_D	0.976	0.46
153_V	254_S	0.970	0.45
291_T	303_G	0.968	0.45
60_A	142_A	0.965	0.45
132_F	188_L	0.965	0.45
110_D	114_T	0.956	0.44
280_V	316_D	0.952	0.44
299_I	303_G	0.948	0.44
58_H	227_P	0.947	0.44
247_T	257_Q	0.944	0.43
28_N	162_F	0.942	0.43
53_Y	253_D	0.940	0.43
103_K	280_V	0.934	0.43
29_S	125_D	0.934	0.43
297_L	315_I	0.932	0.43
53_Y	200_S	0.928	0.42
186_D	242_S	0.927	0.42
60_A	303_G	0.924	0.42
225_R	229_L	0.922	0.42
194_S	199_V	0.921	0.42
36_Q	63_T	0.916	0.42
131_S	160_E	0.914	0.41
31_S	158_D	0.913	0.41
127_R	161_D	0.912	0.41
149_A	301_F	0.911	0.41
260_S	305_S	0.908	0.41
259_S	292_Y	0.907	0.41
226_L	230_A	0.907	0.41
81_K	154_I	0.906	0.41
23_L	63_T	0.904	0.41
60_A	231_T	0.901	0.41
231_T	267_E	0.898	0.40
43_F	112_F	0.894	0.40
51_Q	246_S	0.893	0.40
204_V	244_F	0.893	0.40
280_V	285_D	0.889	0.40
157_S	201_T	0.880	0.39
186_D	195_R	0.879	0.39
33_K	117_K	0.879	0.39
288_N	315_I	0.874	0.39
273_I	283_P	0.869	0.38
159_E	260_S	0.865	0.38
49_R	52_Q	0.864	0.38
135_A	204_V	0.863	0.38
132_F	239_S	0.859	0.38
41_A	313_I	0.859	0.38
112_F	116_A	0.859	0.38
59_M	303_G	0.843	0.37
202_I	238_G	0.831	0.36
268_P	315_I	0.830	0.36
16_I	22_I	0.828	0.36
147_S	229_L	0.827	0.36
17_P	299_I	0.825	0.36
109_G	263_K	0.825	0.36
149_A	307_P	0.824	0.36
150_F	299_I	0.823	0.35
227_P	233_T	0.823	0.35
201_T	246_S	0.811	0.35
68_E	312_N	0.810	0.35
129_F	149_A	0.809	0.35
128_A	161_D	0.809	0.35
134_E	302_H	0.807	0.34
64_T	159_E	0.806	0.34
72_N	75_S	0.805	0.34
25_V	47_I	0.805	0.34
164_S	180_T	0.802	0.34
291_T	296_N	0.800	0.34
265_N	311_A	0.800	0.34
128_A	157_S	0.798	0.34
102_D	106_A	0.796	0.34
157_S	313_I	0.790	0.33
58_H	82_D	0.790	0.33
280_V	310_D	0.788	0.33
25_V	161_D	0.788	0.33
251_I	269_Q	0.784	0.33
18_K	196_N	0.783	0.33
26_I	235_G	0.782	0.33
201_T	232_L	0.778	0.33
129_F	184_Y	0.777	0.33
149_A	292_Y	0.777	0.33
200_S	205_P	0.777	0.33
276_T	281_S	0.769	0.32
23_L	135_A	0.769	0.32
204_V	319_P	0.766	0.32
159_E	202_I	0.766	0.32
64_T	292_Y	0.764	0.32
137_L	196_N	0.764	0.32
119_G	240_L	0.763	0.32
121_L	124_G	0.763	0.32
22_I	163_S	0.760	0.32
63_T	240_L	0.760	0.32
136_L	187_F	0.756	0.31
63_T	301_F	0.755	0.31
130_S	162_F	0.755	0.31
243_N	252_S	0.754	0.31
30_G	162_F	0.753	0.31
22_I	246_S	0.750	0.31
200_S	233_T	0.746	0.31
67_W	296_N	0.743	0.31
27_D	157_S	0.743	0.31
107_N	229_L	0.741	0.30
235_G	272_T	0.740	0.30
42_N	179_H	0.739	0.30
269_Q	272_T	0.737	0.30
299_I	311_A	0.737	0.30
185_V	193_G	0.732	0.30
51_Q	300_T	0.729	0.30
121_L	125_D	0.727	0.30
36_Q	159_E	0.725	0.30
29_S	158_D	0.724	0.29
132_F	270_E	0.724	0.29
29_S	233_T	0.719	0.29
27_D	158_D	0.717	0.29
25_V	131_S	0.712	0.29
151_L	229_L	0.711	0.29
226_L	235_G	0.711	0.29
164_S	225_R	0.710	0.29
110_D	179_H	0.710	0.29
312_N	315_I	0.707	0.28
292_Y	299_I	0.706	0.28
167_A	278_N	0.705	0.28
156_V	161_D	0.703	0.28
65_E	159_E	0.700	0.28
26_I	131_S	0.697	0.28
23_L	146_R	0.697	0.28
153_V	271_D	0.695	0.28
198_S	305_S	0.694	0.28
45_S	116_A	0.692	0.28
49_R	249_E	0.685	0.27
203_T	314_T	0.684	0.27
306_V	309_A	0.683	0.27
206_D	299_I	0.681	0.27
253_D	311_A	0.680	0.27
18_K	131_S	0.679	0.27
112_F	272_T	0.679	0.27
154_I	197_Y	0.678	0.27
251_I	255_I	0.677	0.27
263_K	298_T	0.677	0.27
30_G	63_T	0.676	0.27
148_E	165_S	0.674	0.27
156_V	291_T	0.673	0.27
46_F	151_L	0.671	0.26
269_Q	320_K	0.671	0.26
45_S	119_G	0.670	0.26
39_L	205_P	0.668	0.26
83_G	110_D	0.667	0.26
152_A	229_L	0.666	0.26
19_Q	39_L	0.666	0.26
193_G	315_I	0.665	0.26
159_E	226_L	0.662	0.26
24_W	107_N	0.659	0.26
69_K	112_F	0.656	0.26
200_S	319_P	0.655	0.26
280_V	298_T	0.654	0.26
25_V	245_G	0.654	0.26
247_T	256_I	0.653	0.26
66_A	261_V	0.653	0.26
78_A	285_D	0.650	0.25
24_W	48_S	0.648	0.25
282_V	309_A	0.647	0.25
28_N	72_N	0.646	0.25
116_A	206_D	0.645	0.25
53_Y	201_T	0.644	0.25
25_V	264_L	0.644	0.25
293_D	296_N	0.644	0.25
23_L	64_T	0.642	0.25
255_I	262_F	0.640	0.25
14_V	255_I	0.639	0.25
76_E	235_G	0.638	0.25
232_L	246_S	0.638	0.25
155_I	260_S	0.637	0.25
106_A	249_E	0.637	0.25
28_N	308_A	0.636	0.25
57_F	196_N	0.636	0.25
104_N	282_V	0.636	0.25
15_F	238_G	0.635	0.25
155_I	159_E	0.632	0.24
14_V	263_K	0.632	0.24
18_K	22_I	0.632	0.24
61_V	141_N	0.630	0.24
103_K	256_I	0.630	0.24
157_S	204_V	0.627	0.24
23_L	144_F	0.626	0.24
13_A	105_T	0.626	0.24
84_A	118_Q	0.625	0.24
104_N	108_L	0.623	0.24
47_I	65_E	0.622	0.24
22_I	310_D	0.621	0.24
263_K	295_S	0.620	0.24
28_N	151_L	0.619	0.24
261_V	298_T	0.618	0.24
27_D	126_E	0.617	0.24
245_G	252_S	0.617	0.24
111_V	131_S	0.612	0.23
188_L	202_I	0.610	0.23
25_V	148_E	0.609	0.23
139_P	252_S	0.608	0.23
203_T	276_T	0.607	0.23
37_D	207_D	0.607	0.23
152_A	293_D	0.606	0.23
235_G	241_C	0.604	0.23
8_D	12_Q	0.603	0.23
64_T	248_L	0.601	0.23
110_D	182_Q	0.599	0.23
50_F	136_L	0.599	0.23
300_T	303_G	0.599	0.23
159_E	233_T	0.598	0.23
101_M	264_L	0.596	0.23
50_F	239_S	0.595	0.23
24_W	66_A	0.595	0.23
184_Y	191_Y	0.594	0.23
36_Q	240_L	0.594	0.23
43_F	108_L	0.593	0.22
26_I	240_L	0.592	0.22
204_V	248_L	0.591	0.22
109_G	113_S	0.584	0.22
61_V	154_I	0.581	0.22
101_M	285_D	0.580	0.22
40_A	113_S	0.580	0.22
53_Y	127_R	0.580	0.22
200_S	203_T	0.580	0.22
233_T	260_S	0.580	0.22
116_A	145_R	0.577	0.22
199_V	204_V	0.576	0.22
72_N	76_E	0.576	0.22
285_D	289_G	0.576	0.22
142_A	187_F	0.575	0.22
127_R	155_I	0.575	0.22
15_F	293_D	0.572	0.21
32_M	36_Q	0.571	0.21
84_A	280_V	0.569	0.21
48_S	281_S	0.569	0.21
184_Y	209_C	0.565	0.21
245_G	299_I	0.564	0.21
68_E	250_L	0.564	0.21
151_L	301_F	0.563	0.21
131_S	134_E	0.563	0.21
19_Q	292_Y	0.561	0.21
14_V	52_Q	0.559	0.21
133_K	300_T	0.557	0.21
248_L	254_S	0.556	0.21
182_Q	245_G	0.555	0.21
307_P	317_F	0.555	0.21
147_S	294_A	0.554	0.21
206_D	227_P	0.554	0.21
12_Q	246_S	0.553	0.21
155_I	319_P	0.548	0.20
316_D	319_P	0.547	0.20
42_N	247_T	0.544	0.20
25_V	188_L	0.544	0.20
26_I	75_S	0.541	0.20
21_D	223_S	0.538	0.20
20_I	129_F	0.536	0.20
307_P	310_D	0.536	0.20
312_N	316_D	0.535	0.20
273_I	287_V	0.534	0.20
14_V	312_N	0.533	0.20
25_V	63_T	0.533	0.20
27_D	32_M	0.532	0.20
41_A	57_F	0.530	0.20
135_A	267_E	0.529	0.20
35_S	157_S	0.529	0.20
37_D	221_K	0.528	0.20
186_D	297_L	0.527	0.19
104_N	253_D	0.524	0.19
192_V	301_F	0.524	0.19
112_F	229_L	0.524	0.19
196_N	199_V	0.520	0.19
44_Q	269_Q	0.518	0.19
50_F	285_D	0.517	0.19
74_A	233_T	0.515	0.19
245_G	254_S	0.515	0.19
115_N	280_V	0.515	0.19
76_E	277_V	0.514	0.19
153_V	228_E	0.506	0.19
45_S	157_S	0.506	0.19
19_Q	35_S	0.505	0.19
68_E	308_A	0.504	0.18
156_V	303_G	0.502	0.18
220_R	261_V	0.501	0.18
20_I	46_F	0.500	0.18

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3fcs_B	1	0.9043	99.7	0.748	Contact Map
4um9_B	1	0.8858	99.7	0.754	Contact Map
4neh_B	1	0.9136	99.7	0.755	Contact Map
4wk0_B	1	0.9012	99.7	0.759	Contact Map
4um8_B	1	0.8951	99.7	0.759	Contact Map
3t3p_B	1	0.9012	99.6	0.762	Contact Map
2b2x_A	1	0.571	99.6	0.764	Contact Map
5bv8_A	1	0.6142	99.6	0.765	Contact Map
1q0p_A	1	0.5432	99.6	0.767	Contact Map
1v7p_C	1	0.5648	99.6	0.767	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0088 seconds.