GREMLIN Database
T0922_1_96 - T0922 1-96
ID: 87 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 96 (75)
Sequences: 917 (802)
Seq/√Len: 92.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
68_T71_S3.1471.00
46_M83_Q2.7541.00
84_S89_L2.3671.00
51_N88_G2.3021.00
43_V80_Q2.2981.00
40_S77_L2.1981.00
47_Q84_S2.0701.00
81_F94_P2.0681.00
39_I76_V2.0241.00
68_T72_D1.9531.00
39_I43_V1.8351.00
37_V85_Y1.8341.00
68_T81_F1.6941.00
52_P89_L1.6251.00
50_A87_L1.6171.00
28_P95_V1.6161.00
45_I82_I1.4711.00
42_A86_C1.4681.00
58_T61_G1.4260.99
26_K64_N1.3610.99
46_M87_L1.3570.99
42_A79_A1.2720.99
27_F35_G1.2690.99
42_A83_Q1.2400.98
55_Y61_G1.2300.98
65_A74_V1.2180.98
48_T74_V1.2060.98
69_G93_P1.1800.98
49_M79_A1.1670.98
34_D38_D1.1300.97
28_P69_G1.1060.97
24_V63_I1.0990.97
60_K64_N1.0850.96
38_D87_L1.0820.96
45_I74_V1.0770.96
31_A45_I1.0660.96
67_V82_I1.0640.96
68_T75_T1.0510.96
45_I79_A1.0200.95
69_G72_D1.0130.95
67_V85_Y0.9940.94
31_A74_V0.9910.94
25_Q60_K0.9740.94
79_A83_Q0.9580.93
38_D75_T0.9570.93
33_C61_G0.9490.93
27_F37_V0.9490.93
59_D62_R0.9360.92
80_Q83_Q0.8920.90
81_F84_S0.8830.90
82_I86_C0.8770.89
48_T53_S0.8770.89
81_F93_P0.8720.89
37_V82_I0.8480.88
63_I95_V0.8440.88
26_K63_I0.8400.87
76_V87_L0.8330.87
51_N83_Q0.8310.87
53_S56_Q0.8010.85
42_A88_G0.7860.84
33_C64_N0.7800.83
42_A46_M0.7660.82
42_A80_Q0.7590.81
37_V93_P0.7550.81
84_S90_V0.7420.80
54_K91_E0.7370.79
31_A62_R0.7190.78
66_D78_D0.7180.78
32_N38_D0.7140.77
36_I73_G0.7080.77
48_T56_Q0.7040.76
25_Q63_I0.6970.76
49_M86_C0.6920.75
24_V27_F0.6830.74
28_P67_V0.6620.72
36_I53_S0.6560.71
90_V93_P0.6390.69
43_V79_A0.6380.69
60_K63_I0.6360.69
71_S75_T0.6310.68
56_Q61_G0.6310.68
57_M74_V0.6230.67
88_G91_E0.6230.67
57_M61_G0.6120.66
46_M79_A0.6070.65
45_I86_C0.6060.65
46_M50_A0.6050.65
62_R74_V0.6000.64
50_A77_L0.5990.64
46_M88_G0.5950.64
47_Q52_P0.5840.62
48_T62_R0.5820.62
41_D78_D0.5790.61
49_M80_Q0.5750.61
31_A65_A0.5690.60
49_M88_G0.5650.60
48_T55_Y0.5640.59
66_D72_D0.5640.59
66_D69_G0.5620.59
30_D41_D0.5470.57
50_A75_T0.5460.57
67_V81_F0.5400.56
77_L80_Q0.5300.55
26_K59_D0.5210.54
28_P74_V0.5200.53
29_G41_D0.5170.53
46_M80_Q0.5140.53
56_Q65_A0.5100.52
36_I64_N0.5080.52
40_S88_G0.5060.51
41_D66_D0.5030.51
29_G78_D0.5000.51
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4uyp_B 1 0.7396 99.7 0.102 Contact Map
4fl4_A 1 0.7083 99.7 0.107 Contact Map
4cj0_A 1 0.2083 99.7 0.111 Contact Map
2yik_A 1 0.1875 99.7 0.115 Contact Map
4dh2_B 1 0.7292 99.7 0.133 Contact Map
1daq_A 1 0.7188 99.6 0.171 Contact Map
2y3n_B 1 0.625 99.6 0.191 Contact Map
2ccl_B 1 0.6458 99.5 0.249 Contact Map
2vn6_B 1 0.6667 99.4 0.259 Contact Map
3ul4_B 1 0.6562 99.4 0.266 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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