T0918_1_546 - CASP12 - GREMLIN Contacts

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T0918_1_546 - T0918 1-546

ID:	83	Sequences: MESNNGEAKIQKVKNWSPVWIFPIVTALIGAWVLFYHYSHQGPEVTLITANAEGIEGGKTTIKSRSVDVGVVESATLADDLTHVEIKARLNSGMEKLLHKDTVFWVVKPQIGREGISGLGTLLSGVYIELQPGAKGSKMDKYDLLDSPPLAPPDAKGIRVILDSKKAGQLSPGDPVLFRGYRVGSVETSTFDTQKRNISYQLFINAPYDRLVTNNVRFWKDSGIAVDLTSAGMRVEMGSLTTLLSGGVSFDVPEGLDLGQPVAPKTAFVLYDDQKSIQDSLYTDHIDYLMFFKDSVRGLQPGAPVEFRGIRLGTVSKVPFFAPNMRQTFNDDYRIPVLIRIEPERLKMQLGENADVVEHLGELLKRGLRGSLKTGNLVTGALYVDLDFYPNTPAITGIREFNGYQIIPTVSGGLAQIQQRLMEALDKINKLPLNPMIEQATSTLSESQRTMKNLQTTLDSMNKILASQSMQQLPTDMQSTLRELNRSMQGFQPGSAAYNKMVADMQRLDQVLRELQPVLKTLNEKSNALVFEAKDKKDPEPKRAKQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	546 (511)
Sequences:	1583 (1121)
Seq/√Len:	49.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
47_L	88_A	9.649	1.00
62_I	88_A	7.050	1.00
290_M	339_I	6.175	1.00
290_M	409_T	5.071	1.00
273_D	276_S	4.582	1.00
55_I	75_A	4.342	1.00
521_T	525_K	4.159	1.00
73_E	89_R	4.159	1.00
72_V	86_I	3.997	1.00
61_T	68_D	3.951	1.00
481_L	484_L	3.832	1.00
36_Y	40_H	3.559	1.00
100_K	137_S	3.410	1.00
424_A	428_I	3.248	1.00
447_S	450_T	3.200	1.00
78_A	83_H	3.184	1.00
43_P	90_L	2.926	1.00
176_V	202_L	2.913	1.00
423_E	429_N	2.888	1.00
481_L	488_M	2.866	1.00
35_F	39_S	2.838	1.00
47_L	62_I	2.825	1.00
373_K	385_D	2.806	1.00
185_S	205_N	2.785	1.00
49_T	144_L	2.687	1.00
527_N	531_F	2.667	1.00
428_I	431_L	2.600	1.00
484_L	488_M	2.594	1.00
514_E	519_L	2.554	1.00
226_V	235_V	2.528	1.00
101_D	133_G	2.527	1.00
447_S	451_M	2.471	1.00
427_K	434_N	2.458	1.00
291_F	334_R	2.454	1.00
112_G	115_G	2.434	1.00
288_Y	339_I	2.432	1.00
44_E	89_R	2.429	1.00
183_V	250_F	2.390	1.00
464_I	471_Q	2.373	1.00
483_E	488_M	2.364	1.00
339_I	407_I	2.312	1.00
192_D	199_S	2.303	1.00
460_S	469_S	2.292	1.00
435_P	441_T	2.282	1.00
507_R	516_Q	2.253	1.00
90_L	98_L	2.136	1.00
420_R	426_D	2.094	1.00
100_K	139_M	2.027	1.00
361_G	365_K	2.027	1.00
461_M	465_L	2.006	1.00
314_T	340_R	1.995	1.00
431_L	434_N	1.984	0.99
459_D	471_Q	1.937	0.99
523_N	533_A	1.932	0.99
262_V	268_F	1.931	0.99
176_V	248_V	1.925	0.99
48_I	85_E	1.919	0.99
103_V	131_Q	1.901	0.99
170_L	248_V	1.865	0.99
443_T	447_S	1.859	0.99
53_E	120_G	1.849	0.99
431_L	437_I	1.844	0.99
465_L	471_Q	1.818	0.99
480_T	484_L	1.814	0.99
48_I	83_H	1.784	0.99
167_A	189_S	1.746	0.99
155_A	205_N	1.743	0.99
289_L	336_P	1.736	0.99
481_L	485_N	1.736	0.99
297_R	375_G	1.725	0.99
465_L	468_Q	1.725	0.99
206_A	209_D	1.700	0.98
49_T	86_I	1.696	0.98
464_I	468_Q	1.677	0.98
526_S	532_E	1.676	0.98
20_W	23_P	1.649	0.98
373_K	383_Y	1.649	0.98
459_D	469_S	1.649	0.98
518_V	522_L	1.640	0.98
305_V	339_I	1.635	0.98
186_V	202_L	1.592	0.98
465_L	469_S	1.591	0.98
385_D	389_Y	1.572	0.97
479_S	483_E	1.572	0.97
237_M	243_L	1.565	0.97
69_V	97_L	1.563	0.97
430_K	434_N	1.563	0.97
442_S	448_Q	1.557	0.97
504_D	509_D	1.556	0.97
290_M	384_V	1.543	0.97
364_L	396_T	1.541	0.97
291_F	336_P	1.530	0.97
459_D	462_N	1.530	0.97
361_G	400_E	1.526	0.97
508_L	511_V	1.517	0.97
373_K	389_Y	1.514	0.97
297_R	306_E	1.503	0.97
433_L	437_I	1.491	0.96
464_I	469_S	1.489	0.96
460_S	465_L	1.479	0.96
99_H	133_G	1.477	0.96
509_D	512_L	1.476	0.96
102_T	130_L	1.472	0.96
457_T	462_N	1.469	0.96
159_R	187_E	1.453	0.96
459_D	465_L	1.448	0.96
178_F	364_L	1.447	0.96
521_T	533_A	1.440	0.96
372_L	384_V	1.437	0.95
110_Q	148_P	1.425	0.95
101_D	136_G	1.423	0.95
160_V	202_L	1.416	0.95
311_R	314_T	1.408	0.95
439_Q	448_Q	1.404	0.95
56_E	59_K	1.401	0.95
316_S	338_L	1.400	0.95
459_D	464_I	1.400	0.95
399_R	402_N	1.400	0.95
263_A	266_T	1.399	0.95
505_M	528_A	1.394	0.95
424_A	429_N	1.387	0.95
165_K	376_N	1.382	0.94
101_D	135_K	1.381	0.94
301_P	318_V	1.379	0.94
507_R	510_Q	1.372	0.94
375_G	383_Y	1.366	0.94
399_R	404_Y	1.363	0.94
342_E	345_R	1.354	0.94
108_K	144_L	1.354	0.94
27_A	82_T	1.340	0.93
251_D	274_Q	1.333	0.93
446_E	450_T	1.318	0.93
464_I	470_M	1.312	0.93
457_T	465_L	1.312	0.93
481_L	487_S	1.308	0.93
274_Q	278_Q	1.308	0.93
72_V	144_L	1.304	0.92
86_I	144_L	1.301	0.92
158_I	209_D	1.297	0.92
95_E	140_D	1.296	0.92
287_D	340_R	1.293	0.92
214_N	262_V	1.293	0.92
159_R	201_Q	1.291	0.92
310_I	335_I	1.290	0.92
294_D	415_A	1.288	0.92
467_S	471_Q	1.288	0.92
484_L	487_S	1.288	0.92
296_V	335_I	1.282	0.92
389_Y	392_T	1.282	0.92
97_L	130_L	1.273	0.92
221_D	238_G	1.272	0.92
501_M	505_M	1.257	0.91
77_L	97_L	1.256	0.91
461_M	464_I	1.254	0.91
32_W	36_Y	1.251	0.91
230_S	304_P	1.242	0.91
192_D	197_N	1.237	0.90
497_A	501_M	1.236	0.90
208_Y	211_L	1.233	0.90
495_S	511_V	1.232	0.90
525_K	533_A	1.230	0.90
132_P	342_E	1.229	0.90
511_V	514_E	1.227	0.90
392_T	395_I	1.225	0.90
49_T	72_V	1.225	0.90
316_S	340_R	1.214	0.89
495_S	498_Y	1.210	0.89
45_V	142_Y	1.209	0.89
389_Y	410_V	1.206	0.89
308_R	387_D	1.196	0.89
399_R	406_I	1.195	0.89
290_M	370_G	1.188	0.88
229_T	234_R	1.184	0.88
512_L	516_Q	1.183	0.88
520_K	524_E	1.181	0.88
164_S	200_Y	1.179	0.88
466_A	469_S	1.179	0.88
221_D	249_S	1.178	0.88
480_T	483_E	1.173	0.88
74_S	87_K	1.173	0.88
463_K	469_S	1.173	0.88
400_E	405_Q	1.171	0.88
468_Q	471_Q	1.168	0.88
431_L	436_M	1.165	0.87
420_R	425_L	1.165	0.87
102_T	116_I	1.164	0.87
32_W	98_L	1.162	0.87
62_I	90_L	1.154	0.87
439_Q	445_S	1.151	0.87
200_Y	368_L	1.140	0.86
521_T	528_A	1.132	0.86
240_L	244_L	1.130	0.86
371_S	385_D	1.120	0.85
48_I	143_D	1.120	0.85
31_A	36_Y	1.115	0.85
57_G	75_A	1.112	0.85
98_L	130_L	1.110	0.85
61_T	71_V	1.108	0.85
81_L	97_L	1.108	0.85
432_P	437_I	1.107	0.85
480_T	485_N	1.106	0.85
417_I	421_L	1.099	0.84
212_V	216_V	1.096	0.84
272_D	276_S	1.091	0.84
525_K	531_F	1.090	0.84
46_T	85_E	1.089	0.84
213_T	252_V	1.089	0.84
101_D	134_A	1.087	0.84
46_T	141_K	1.083	0.83
524_E	527_N	1.080	0.83
76_T	87_K	1.076	0.83
317_K	338_L	1.074	0.83
303_A	375_G	1.073	0.83
90_L	94_M	1.072	0.83
50_A	146_D	1.069	0.82
438_E	441_T	1.056	0.82
483_E	487_S	1.054	0.82
160_V	212_V	1.053	0.82
141_K	427_K	1.049	0.81
307_F	383_Y	1.048	0.81
62_I	98_L	1.046	0.81
460_S	466_A	1.043	0.81
480_T	488_M	1.039	0.81
491_F	498_Y	1.039	0.81
130_L	154_D	1.037	0.81
21_I	25_V	1.032	0.80
458_L	465_L	1.029	0.80
236_E	274_Q	1.027	0.80
86_I	128_I	1.023	0.80
307_F	363_L	1.016	0.79
150_L	240_L	1.008	0.79
10_I	14_K	1.008	0.79
23_P	26_T	1.005	0.78
202_L	248_V	1.001	0.78
282_Y	342_E	0.993	0.78
51_N	106_V	0.981	0.77
30_G	34_L	0.976	0.76
297_R	383_Y	0.971	0.76
21_I	24_I	0.970	0.76
234_R	273_D	0.968	0.76
25_V	28_L	0.968	0.76
514_E	521_T	0.968	0.76
52_A	75_A	0.967	0.76
458_L	461_M	0.965	0.75
224_I	392_T	0.964	0.75
436_M	440_A	0.963	0.75
369_R	392_T	0.963	0.75
362_E	365_K	0.962	0.75
180_G	211_L	0.959	0.75
427_K	431_L	0.958	0.75
300_Q	500_K	0.957	0.75
522_L	528_A	0.957	0.75
399_R	403_G	0.955	0.75
462_N	466_A	0.951	0.74
423_E	426_D	0.951	0.74
63_K	156_K	0.950	0.74
292_F	372_L	0.950	0.74
299_L	303_A	0.950	0.74
106_V	144_L	0.947	0.74
287_D	316_S	0.947	0.74
457_T	460_S	0.945	0.74
44_E	87_K	0.944	0.74
306_E	311_R	0.942	0.74
69_V	130_L	0.941	0.74
526_S	530_V	0.941	0.74
93_G	240_L	0.938	0.73
166_K	180_G	0.934	0.73
64_S	129_E	0.933	0.73
511_V	515_L	0.932	0.73
22_F	27_A	0.928	0.73
289_L	338_L	0.927	0.73
391_N	487_S	0.921	0.72
22_F	34_L	0.920	0.72
456_T	459_D	0.917	0.72
44_E	73_E	0.913	0.71
190_T	201_Q	0.909	0.71
160_V	170_L	0.902	0.70
498_Y	502_V	0.902	0.70
142_Y	181_Y	0.900	0.70
64_S	174_D	0.898	0.70
285_H	342_E	0.897	0.70
301_P	316_S	0.896	0.70
339_I	384_V	0.894	0.70
56_E	120_G	0.893	0.70
43_P	323_P	0.892	0.70
231_A	300_Q	0.888	0.69
268_F	384_V	0.886	0.69
490_G	498_Y	0.884	0.69
88_A	98_L	0.883	0.69
462_N	465_L	0.882	0.69
108_K	146_D	0.882	0.69
24_I	257_D	0.881	0.69
80_D	83_H	0.880	0.69
138_K	421_L	0.879	0.68
22_F	374_T	0.878	0.68
213_T	412_G	0.875	0.68
66_S	97_L	0.874	0.68
528_A	532_E	0.873	0.68
215_N	256_L	0.870	0.68
259_G	414_L	0.869	0.68
308_R	335_I	0.868	0.67
455_Q	461_M	0.862	0.67
263_A	386_L	0.861	0.67
22_F	26_T	0.859	0.67
124_S	312_L	0.859	0.67
500_K	506_Q	0.856	0.66
53_E	181_Y	0.856	0.66
103_V	145_L	0.855	0.66
357_V	361_G	0.854	0.66
69_V	505_M	0.853	0.66
53_E	108_K	0.850	0.66
13_V	16_W	0.850	0.66
416_Q	419_Q	0.849	0.66
483_E	486_R	0.846	0.65
421_L	425_L	0.834	0.64
41_Q	44_E	0.834	0.64
481_L	486_R	0.833	0.64
511_V	532_E	0.830	0.64
164_S	248_V	0.829	0.64
72_V	128_I	0.829	0.64
291_F	321_F	0.828	0.64
110_Q	303_A	0.826	0.64
67_V	84_V	0.826	0.64
30_G	87_K	0.823	0.63
167_A	200_Y	0.822	0.63
507_R	513_R	0.821	0.63
311_R	342_E	0.820	0.63
55_I	126_V	0.819	0.63
458_L	463_K	0.818	0.63
22_F	502_V	0.818	0.63
485_N	488_M	0.817	0.63
47_L	144_L	0.815	0.63
176_V	204_I	0.815	0.63
465_L	482_R	0.815	0.63
45_V	148_P	0.811	0.62
456_T	462_N	0.807	0.62
370_G	384_V	0.807	0.62
387_D	427_K	0.806	0.62
112_G	245_S	0.805	0.62
69_V	81_L	0.804	0.61
290_M	407_I	0.804	0.61
102_T	109_P	0.800	0.61
515_L	519_L	0.800	0.61
88_A	439_Q	0.799	0.61
425_L	428_I	0.798	0.61
164_S	360_L	0.796	0.61
188_T	200_Y	0.795	0.61
19_V	33_V	0.794	0.61
168_G	369_R	0.793	0.60
371_S	411_S	0.789	0.60
45_V	88_A	0.788	0.60
117_S	215_N	0.787	0.60
291_F	406_I	0.786	0.60
272_D	447_S	0.785	0.60
462_N	469_S	0.783	0.59
392_T	396_T	0.783	0.59
179_R	432_P	0.783	0.59
436_M	445_S	0.782	0.59
526_S	533_A	0.781	0.59
300_Q	381_A	0.778	0.59
131_Q	151_A	0.775	0.59
111_I	426_D	0.775	0.59
73_E	276_S	0.771	0.58
186_V	221_D	0.769	0.58
122_L	213_T	0.768	0.58
460_S	467_S	0.766	0.58
302_G	314_T	0.765	0.58
296_V	308_R	0.764	0.58
160_V	198_I	0.763	0.57
115_G	124_S	0.762	0.57
45_V	62_I	0.762	0.57
109_P	124_S	0.761	0.57
33_V	36_Y	0.761	0.57
110_Q	117_S	0.759	0.57
82_T	154_D	0.758	0.57
323_P	417_I	0.757	0.57
464_I	467_S	0.755	0.57
92_S	95_E	0.755	0.57
62_I	72_V	0.755	0.57
354_A	358_E	0.753	0.56
398_I	407_I	0.752	0.56
28_L	31_A	0.751	0.56
37_H	346_L	0.748	0.56
371_S	389_Y	0.747	0.56
201_Q	265_K	0.746	0.56
484_L	500_K	0.746	0.56
183_V	208_Y	0.744	0.56
511_V	517_P	0.744	0.56
293_K	411_S	0.744	0.56
512_L	517_P	0.742	0.55
98_L	339_I	0.742	0.55
450_T	468_Q	0.741	0.55
83_H	96_K	0.741	0.55
336_P	339_I	0.741	0.55
216_V	350_L	0.741	0.55
420_R	429_N	0.740	0.55
92_S	293_K	0.740	0.55
440_A	443_T	0.740	0.55
51_N	144_L	0.739	0.55
24_I	440_A	0.739	0.55
22_F	485_N	0.738	0.55
253_P	259_G	0.736	0.55
171_S	333_Y	0.735	0.55
99_H	130_L	0.735	0.55
464_I	480_T	0.734	0.55
34_L	181_Y	0.731	0.54
118_G	121_T	0.730	0.54
521_T	527_N	0.730	0.54
207_P	345_R	0.727	0.54
421_L	424_A	0.725	0.54
92_S	382_L	0.724	0.54
240_L	324_N	0.724	0.54
461_M	467_S	0.724	0.54
204_I	241_T	0.723	0.53
106_V	153_P	0.720	0.53
497_A	500_K	0.720	0.53
282_Y	345_R	0.719	0.53
158_I	264_P	0.719	0.53
144_L	174_D	0.717	0.53
8_A	97_L	0.716	0.53
56_E	61_T	0.715	0.53
20_W	26_T	0.715	0.53
142_Y	176_V	0.714	0.52
492_Q	530_V	0.712	0.52
36_Y	39_S	0.711	0.52
436_M	439_Q	0.709	0.52
514_E	517_P	0.709	0.52
213_T	335_I	0.708	0.52
439_Q	495_S	0.707	0.52
358_E	362_E	0.706	0.52
239_S	309_G	0.704	0.51
194_Q	199_S	0.704	0.51
109_P	115_G	0.704	0.51
307_F	346_L	0.702	0.51
273_D	343_P	0.700	0.51
186_V	200_Y	0.698	0.51
62_I	416_Q	0.698	0.51
440_A	444_L	0.696	0.51
491_F	497_A	0.694	0.50
132_P	180_G	0.693	0.50
72_V	75_A	0.691	0.50
101_D	137_S	0.691	0.50
163_D	267_A	0.691	0.50
212_V	217_R	0.691	0.50
248_V	267_A	0.690	0.50
191_F	336_P	0.689	0.50
163_D	197_N	0.689	0.50
512_L	522_L	0.688	0.50
521_T	531_F	0.687	0.50
287_D	341_I	0.687	0.50
248_V	312_L	0.687	0.50
216_V	252_V	0.686	0.50
235_V	495_S	0.684	0.49
304_P	363_L	0.682	0.49
134_A	154_D	0.681	0.49
167_A	440_A	0.678	0.49
22_F	25_V	0.677	0.49
52_A	248_V	0.677	0.49
57_G	376_N	0.677	0.49
225_A	236_E	0.677	0.49
233_M	409_T	0.676	0.49
174_D	292_F	0.675	0.49
170_L	200_Y	0.674	0.48
72_V	88_A	0.674	0.48
377_L	444_L	0.674	0.48
224_I	243_L	0.674	0.48
176_V	442_S	0.672	0.48
505_M	511_V	0.672	0.48
204_I	353_N	0.670	0.48
202_L	271_Y	0.670	0.48
294_D	431_L	0.670	0.48
21_I	286_I	0.670	0.48
97_L	495_S	0.669	0.48
273_D	317_K	0.669	0.48
8_A	14_K	0.668	0.48
224_I	410_V	0.668	0.48
29_I	45_V	0.667	0.48
428_I	447_S	0.666	0.48
450_T	458_L	0.665	0.47
221_D	239_S	0.664	0.47
516_Q	532_E	0.664	0.47
259_G	426_D	0.662	0.47
376_N	379_T	0.661	0.47
332_D	366_R	0.660	0.47
35_F	41_Q	0.659	0.47
159_R	209_D	0.659	0.47
233_M	323_P	0.657	0.47
154_D	361_G	0.657	0.47
201_Q	228_L	0.657	0.47
450_T	467_S	0.657	0.47
154_D	344_E	0.657	0.47
186_V	384_V	0.656	0.47
19_V	39_S	0.654	0.46
223_G	232_G	0.654	0.46
465_L	470_M	0.654	0.46
75_A	490_G	0.653	0.46
285_H	378_V	0.652	0.46
176_V	265_K	0.652	0.46
136_G	243_L	0.652	0.46
85_E	224_I	0.651	0.46
485_N	530_V	0.651	0.46
33_V	40_H	0.651	0.46
130_L	528_A	0.650	0.46
430_K	435_P	0.650	0.46
228_L	233_M	0.649	0.46
10_I	277_I	0.649	0.46
63_K	161_I	0.646	0.46
185_S	420_R	0.646	0.46
281_L	340_R	0.644	0.45
57_G	106_V	0.643	0.45
9_K	24_I	0.642	0.45
290_M	305_V	0.642	0.45
155_A	362_E	0.641	0.45
461_M	466_A	0.641	0.45
363_L	437_I	0.641	0.45
308_R	388_F	0.639	0.45
427_K	432_P	0.639	0.45
516_Q	522_L	0.639	0.45
290_M	388_F	0.639	0.45
401_F	406_I	0.639	0.45
48_I	86_I	0.639	0.45
296_V	384_V	0.637	0.45
491_F	495_S	0.636	0.45
51_N	94_M	0.636	0.45
26_T	230_S	0.636	0.45
45_V	265_K	0.635	0.44
357_V	407_I	0.633	0.44
62_I	412_G	0.631	0.44
41_Q	89_R	0.630	0.44
527_N	530_V	0.628	0.44
293_K	332_D	0.627	0.44
11_Q	83_H	0.626	0.44
238_G	242_T	0.625	0.43
164_S	198_I	0.624	0.43
109_P	182_R	0.623	0.43
220_K	223_G	0.623	0.43
516_Q	528_A	0.619	0.43
89_R	385_D	0.619	0.43
210_R	278_Q	0.619	0.43
507_R	532_E	0.619	0.43
331_D	362_E	0.618	0.43
266_T	493_P	0.618	0.43
11_Q	16_W	0.618	0.43
262_V	266_T	0.617	0.43
306_E	385_D	0.617	0.43
66_S	164_S	0.615	0.42
240_L	428_I	0.614	0.42
161_I	201_Q	0.614	0.42
226_V	499_N	0.613	0.42
83_H	176_V	0.613	0.42
102_T	312_L	0.613	0.42
355_D	358_E	0.612	0.42
457_T	468_Q	0.612	0.42
41_Q	376_N	0.612	0.42
130_L	376_N	0.612	0.42
47_L	128_I	0.611	0.42
303_A	383_Y	0.611	0.42
446_E	451_M	0.610	0.42
84_V	292_F	0.610	0.42
204_I	405_Q	0.609	0.42
83_H	318_V	0.608	0.42
289_L	401_F	0.608	0.42
286_I	341_I	0.607	0.42
218_F	370_G	0.606	0.42
514_E	532_E	0.606	0.42
16_W	460_S	0.605	0.41
75_A	416_Q	0.605	0.41
455_Q	458_L	0.604	0.41
436_M	457_T	0.603	0.41
271_Y	294_D	0.602	0.41
160_V	527_N	0.599	0.41
164_S	259_G	0.599	0.41
368_L	386_L	0.598	0.41
269_V	272_D	0.597	0.41
203_F	206_A	0.597	0.41
526_S	529_L	0.596	0.41
459_D	467_S	0.596	0.41
292_F	409_T	0.595	0.40
21_I	45_V	0.595	0.40
103_V	271_Y	0.594	0.40
92_S	140_D	0.594	0.40
242_T	245_S	0.593	0.40
22_F	318_V	0.593	0.40
346_L	360_L	0.592	0.40
497_A	502_V	0.592	0.40
172_P	188_T	0.592	0.40
371_S	413_G	0.591	0.40
235_V	402_N	0.590	0.40
301_P	304_P	0.588	0.40
504_D	518_V	0.588	0.40
12_K	374_T	0.587	0.40
524_E	532_E	0.587	0.40
491_F	514_E	0.587	0.40
52_A	223_G	0.586	0.40
305_V	384_V	0.586	0.40
170_L	279_D	0.586	0.40
293_K	334_R	0.585	0.39
297_R	382_L	0.585	0.39
492_Q	500_K	0.584	0.39
72_V	194_Q	0.584	0.39
192_D	337_V	0.584	0.39
436_M	441_T	0.583	0.39
19_V	466_A	0.583	0.39
416_Q	420_R	0.582	0.39
120_G	288_Y	0.581	0.39
34_L	159_R	0.581	0.39
32_W	342_E	0.580	0.39
240_L	282_Y	0.579	0.39
64_S	436_M	0.579	0.39
305_V	315_V	0.579	0.39
25_V	240_L	0.579	0.39
510_Q	513_R	0.578	0.39
505_M	508_L	0.576	0.39
231_A	391_N	0.576	0.39
170_L	483_E	0.575	0.39
65_R	131_Q	0.575	0.39
53_E	63_K	0.575	0.39
223_G	298_G	0.575	0.39
16_W	90_L	0.572	0.38
441_T	444_L	0.572	0.38
507_R	511_V	0.571	0.38
69_V	83_H	0.570	0.38
129_E	430_K	0.570	0.38
78_A	85_E	0.570	0.38
217_R	343_P	0.570	0.38
133_G	198_I	0.570	0.38
459_D	463_K	0.568	0.38
123_L	180_G	0.567	0.38
99_H	138_K	0.567	0.38
322_A	333_Y	0.567	0.38
297_R	303_A	0.566	0.38
63_K	66_S	0.566	0.38
383_Y	417_I	0.566	0.38
55_I	68_D	0.566	0.38
323_P	333_Y	0.565	0.38
310_I	402_N	0.565	0.38
87_K	353_N	0.564	0.37
58_G	74_S	0.564	0.37
203_F	207_P	0.562	0.37
75_A	507_R	0.560	0.37
62_I	109_P	0.560	0.37
227_D	303_A	0.559	0.37
319_P	336_P	0.557	0.37
41_Q	310_I	0.557	0.37
212_V	440_A	0.557	0.37
99_H	139_M	0.556	0.37
36_Y	116_I	0.556	0.37
412_G	425_L	0.555	0.37
49_T	364_L	0.554	0.36
455_Q	459_D	0.554	0.36
448_Q	451_M	0.554	0.36
337_V	387_D	0.553	0.36
24_I	251_D	0.552	0.36
333_Y	436_M	0.552	0.36
160_V	262_V	0.552	0.36
134_A	176_V	0.551	0.36
307_F	422_M	0.550	0.36
517_P	521_T	0.550	0.36
94_M	130_L	0.550	0.36
310_I	363_L	0.550	0.36
439_Q	442_S	0.550	0.36
127_Y	208_Y	0.548	0.36
435_P	438_E	0.548	0.36
288_Y	530_V	0.547	0.36
292_F	387_D	0.547	0.36
117_S	270_L	0.546	0.36
151_A	170_L	0.546	0.36
29_I	523_N	0.545	0.36
79_D	360_L	0.544	0.36
188_T	244_L	0.543	0.35
32_W	336_P	0.543	0.35
224_I	266_T	0.543	0.35
204_I	385_D	0.542	0.35
89_R	414_L	0.541	0.35
364_L	407_I	0.540	0.35
182_R	248_V	0.540	0.35
273_D	338_L	0.539	0.35
168_G	222_S	0.539	0.35
172_P	189_S	0.538	0.35
129_E	360_L	0.538	0.35
479_S	485_N	0.537	0.35
86_I	140_D	0.537	0.35
418_Q	510_Q	0.536	0.35
178_F	352_E	0.536	0.35
364_L	369_R	0.536	0.35
166_K	238_G	0.535	0.35
292_F	337_V	0.535	0.35
446_E	462_N	0.535	0.35
528_A	531_F	0.534	0.35
372_L	376_N	0.533	0.35
227_D	420_R	0.533	0.35
67_V	127_Y	0.532	0.34
511_V	516_Q	0.532	0.34
9_K	13_V	0.532	0.34
109_P	191_F	0.532	0.34
364_L	383_Y	0.532	0.34
77_L	245_S	0.531	0.34
325_M	330_N	0.530	0.34
58_G	429_N	0.528	0.34
361_G	398_I	0.527	0.34
74_S	204_I	0.527	0.34
434_N	438_E	0.525	0.34
91_N	428_I	0.524	0.34
291_F	417_I	0.524	0.34
226_V	236_E	0.524	0.34
83_H	275_K	0.524	0.34
459_D	480_T	0.523	0.34
306_E	310_I	0.523	0.34
264_P	303_A	0.521	0.33
261_P	354_A	0.521	0.33
190_T	193_T	0.521	0.33
234_R	514_E	0.520	0.33
121_T	247_G	0.520	0.33
164_S	192_D	0.520	0.33
40_H	236_E	0.519	0.33
222_S	247_G	0.519	0.33
427_K	433_L	0.518	0.33
357_V	400_E	0.518	0.33
230_S	375_G	0.517	0.33
368_L	388_F	0.517	0.33
88_A	142_Y	0.517	0.33
518_V	526_S	0.516	0.33
62_I	276_S	0.516	0.33
516_Q	520_K	0.516	0.33
233_M	336_P	0.516	0.33
308_R	320_F	0.516	0.33
86_I	397_G	0.515	0.33
227_D	396_T	0.515	0.33
381_A	425_L	0.514	0.33
180_G	195_K	0.513	0.33
48_I	81_L	0.512	0.33
126_V	415_A	0.511	0.33
19_V	23_P	0.511	0.33
289_L	404_Y	0.511	0.33
126_V	417_I	0.510	0.32
31_A	465_L	0.510	0.32
211_L	293_K	0.508	0.32
172_P	251_D	0.508	0.32
90_L	159_R	0.508	0.32
69_V	383_Y	0.508	0.32
63_K	382_L	0.507	0.32
45_V	504_D	0.507	0.32
387_D	443_T	0.507	0.32
190_T	492_Q	0.506	0.32
242_T	522_L	0.506	0.32
284_D	344_E	0.506	0.32
99_H	135_K	0.506	0.32
441_T	495_S	0.506	0.32
57_G	74_S	0.506	0.32
466_A	515_L	0.505	0.32
455_Q	464_I	0.505	0.32
139_M	142_Y	0.505	0.32
366_R	372_L	0.505	0.32
90_L	493_P	0.504	0.32
227_D	234_R	0.504	0.32
500_K	509_D	0.503	0.32
24_I	27_A	0.503	0.32
22_F	80_D	0.503	0.32
458_L	467_S	0.502	0.32
230_S	274_Q	0.501	0.32
46_T	87_K	0.501	0.32
309_G	372_L	0.501	0.32
318_V	442_S	0.501	0.32
266_T	519_L	0.500	0.32
222_S	239_S	0.500	0.32
493_P	504_D	0.500	0.32

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i3m_A	1	0.2326	46.8	0.98	Contact Map
2xzr_A	1	0.1905	45.9	0.98	Contact Map
4q4g_X	1	0	45	0.98	Contact Map
3tul_A	1	0.1941	42.7	0.98	Contact Map
1tr2_A	1	0.2051	39.6	0.981	Contact Map
3ghg_C	1	0.2564	38.8	0.981	Contact Map
2kvp_A	1	0.2582	38.7	0.981	Contact Map
2c5k_T	1	0.1447	37.1	0.981	Contact Map
4jkv_A	1	0.2125	37	0.981	Contact Map
2dnx_A	1	0.2106	33.1	0.981	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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