T0912_1_624 - CASP12 - GREMLIN Contacts

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T0912_1_624 - T0912 1-624

ID:	75	Sequences: MGSSHHHHHHSSGPQQGLRHLLSAGEIWISPQGNDLNDGTRPSPKATLTSALRQAREWRRTDDERVRGGITICMEGGTYALYEPVFIRPEDSGTEDSPTVIRPVADEKVVLSGGIRIGGWKKQGKLWVADVPMFNGRPLDFRQLWVNGKKAVRARDVEDFEKMNRICSVDEKNEILYVPAVAIRRLVDGKGALKAKYAEMVLHQMWCVANLRIRSVELAGDSAAIRFHQPESRIQFEHPWPRPMVTTDGHNSAFYLTNARELLDVAGEWYHDIDARKVYYYPREGEKLQDAGTEVIVPAIETLIQVKGTFDRPVSHIRFEKITFSHTTWMRPSEKGHVPLQAGMYLTDGYRIDPKMERDYLNHPLDNQGWLGRPAAAVSVAAANQIDFERCRFDHLGSTGLDYEEAVQGGVVRGCLFRDIAGNGLVVGSFSPAAHETHLPYDPTDLREVCAHQQISNCYFTEVGNEDWGCLAILAGYVKDINIEHNEICEVPYSGISLGWGWTQTVNCMRNNRVHANLIHHYAKHMYDVAGVYTLGSQPKSYVTENCVHSIYKPGYVHDPNHWFYLYTDEGSSFITVRDNWTEGEKYLQNANGPGNVWENNGPQVDTVIRERAGLEAEYRDLKK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	624 (527)
Sequences:	1267 (1077)
Seq/√Len:	46.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
75_E	107_E	5.094	1.00
75_E	104_V	4.139	1.00
158_E	264_D	4.044	1.00
45_K	54_Q	3.888	1.00
76_G	107_E	3.874	1.00
27_I	45_K	3.519	1.00
128_V	277_K	3.511	1.00
515_H	544_T	3.428	1.00
264_D	268_E	3.424	1.00
103_P	109_V	3.404	1.00
56_R	91_D	3.325	1.00
102_R	320_E	3.215	1.00
45_K	50_S	3.177	1.00
104_V	107_E	3.034	1.00
417_F	420_I	3.030	1.00
31_P	74_M	3.030	1.00
458_C	486_N	2.895	1.00
87_I	317_I	2.833	1.00
523_A	529_V	2.829	1.00
272_D	275_A	2.792	1.00
518_L	549_H	2.781	1.00
37_N	43_S	2.772	1.00
568_T	577_V	2.770	1.00
52_L	101_I	2.663	1.00
103_P	321_K	2.595	1.00
393_F	396_L	2.571	1.00
393_F	417_F	2.519	1.00
415_C	458_C	2.516	1.00
391_C	415_C	2.469	1.00
380_V	383_A	2.454	1.00
316_H	385_Q	2.430	1.00
72_I	101_I	2.414	1.00
49_T	83_E	2.335	1.00
117_I	129_A	2.328	1.00
410_G	453_Q	2.327	1.00
485_H	516_A	2.315	1.00
38_D	43_S	2.313	1.00
456_S	484_E	2.306	1.00
385_Q	409_G	2.305	1.00
486_N	517_N	2.253	1.00
484_E	515_H	2.249	1.00
550_S	584_G	2.235	1.00
392_R	418_R	2.231	1.00
52_L	87_I	2.207	1.00
409_G	452_H	2.190	1.00
462_E	490_E	2.185	1.00
320_E	389_E	2.155	1.00
74_M	322_I	2.139	1.00
73_C	104_V	2.123	1.00
463_V	491_V	2.117	1.00
578_R	599_E	2.094	1.00
319_F	388_F	2.044	1.00
38_D	42_P	2.029	0.99
416_L	461_T	1.989	0.99
417_F	424_G	1.984	0.99
39_G	44_P	1.953	0.99
519_I	548_V	1.931	0.99
87_I	91_D	1.915	0.99
395_H	419_D	1.901	0.99
121_K	128_V	1.897	0.99
114_G	296_I	1.887	0.99
498_L	514_V	1.886	0.99
50_S	54_Q	1.874	0.99
487_E	520_H	1.862	0.99
158_E	268_E	1.818	0.99
475_A	478_V	1.815	0.99
40_T	43_S	1.803	0.99
541_S	575_I	1.776	0.99
545_E	579_D	1.768	0.99
48_L	87_I	1.766	0.99
475_A	483_I	1.760	0.98
74_M	111_L	1.750	0.98
52_L	91_D	1.734	0.98
315_S	384_N	1.731	0.98
566_L	577_V	1.727	0.98
94_T	98_P	1.725	0.98
480_D	511_N	1.717	0.98
76_G	109_V	1.709	0.98
378_V	393_F	1.709	0.98
81_L	300_I	1.708	0.98
78_T	112_S	1.706	0.98
35_D	47_T	1.690	0.98
383_A	410_G	1.682	0.98
287_K	291_A	1.680	0.98
98_P	316_H	1.671	0.98
28_W	75_E	1.665	0.98
27_I	54_Q	1.663	0.98
411_V	454_Q	1.657	0.98
566_L	582_T	1.653	0.98
85_V	304_I	1.650	0.98
198_A	213_I	1.640	0.98
35_D	44_P	1.635	0.98
48_L	85_V	1.635	0.98
141_F	271_H	1.632	0.97
80_A	296_I	1.631	0.97
91_D	101_I	1.619	0.97
35_D	39_G	1.612	0.97
112_S	326_H	1.610	0.97
35_D	46_A	1.602	0.97
35_D	50_S	1.599	0.97
52_L	56_R	1.593	0.97
69_G	98_P	1.589	0.97
459_Y	489_C	1.586	0.97
325_S	394_D	1.573	0.97
197_Y	273_I	1.568	0.97
427_V	455_I	1.554	0.97
26_E	73_C	1.553	0.97
516_A	545_E	1.552	0.97
487_E	518_L	1.546	0.97
37_N	42_P	1.543	0.96
37_N	40_T	1.542	0.96
84_P	300_I	1.538	0.96
109_V	321_K	1.535	0.96
453_Q	481_I	1.531	0.96
116_R	294_E	1.521	0.96
401_L	417_F	1.519	0.96
306_V	380_V	1.516	0.96
403_Y	410_G	1.492	0.96
103_P	107_E	1.479	0.95
380_V	386_I	1.478	0.95
324_F	393_F	1.477	0.95
495_G	519_I	1.471	0.95
473_I	488_I	1.469	0.95
283_R	286_E	1.462	0.95
52_L	72_I	1.456	0.95
280_Y	286_E	1.451	0.95
478_V	481_I	1.450	0.95
71_T	102_R	1.439	0.95
49_T	52_L	1.435	0.95
146_V	151_A	1.434	0.95
378_V	401_L	1.433	0.95
72_I	87_I	1.427	0.95
48_L	74_M	1.424	0.94
460_F	488_I	1.423	0.94
389_E	414_G	1.418	0.94
271_H	276_R	1.417	0.94
544_T	578_R	1.417	0.94
76_G	103_P	1.414	0.94
488_I	491_V	1.412	0.94
87_I	101_I	1.412	0.94
155_R	255_Y	1.399	0.94
458_C	517_N	1.397	0.94
399_T	423_N	1.394	0.94
288_L	291_A	1.393	0.94
377_A	396_L	1.389	0.94
414_G	457_N	1.388	0.94
425_L	473_I	1.385	0.94
473_I	496_I	1.383	0.94
154_A	264_D	1.382	0.94
259_A	262_L	1.379	0.93
130_D	277_K	1.375	0.93
260_R	279_Y	1.370	0.93
302_T	305_Q	1.369	0.93
287_K	290_D	1.363	0.93
314_V	317_I	1.362	0.93
52_L	99_T	1.361	0.93
280_Y	283_R	1.360	0.93
407_V	410_G	1.357	0.93
85_V	101_I	1.355	0.93
417_F	460_F	1.353	0.93
521_H	524_K	1.351	0.93
115_I	299_A	1.342	0.92
490_E	521_H	1.338	0.92
403_Y	453_Q	1.337	0.92
101_I	319_F	1.336	0.92
54_Q	57_E	1.326	0.92
151_A	280_Y	1.324	0.92
142_R	199_E	1.319	0.92
304_I	412_V	1.302	0.91
288_L	295_V	1.296	0.91
140_D	273_I	1.292	0.91
66_V	70_I	1.290	0.91
153_R	257_T	1.289	0.91
73_C	102_R	1.288	0.91
531_G	548_V	1.280	0.91
114_G	326_H	1.280	0.91
318_R	387_D	1.276	0.90
99_T	319_F	1.270	0.90
123_Q	126_L	1.263	0.90
150_K	419_D	1.260	0.90
93_G	316_H	1.249	0.89
100_V	318_R	1.246	0.89
154_A	268_E	1.235	0.89
76_G	104_V	1.232	0.89
543_V	577_V	1.222	0.88
576_T	599_E	1.222	0.88
95_E	98_P	1.222	0.88
323_T	392_R	1.219	0.88
266_A	281_Y	1.218	0.88
383_A	386_I	1.205	0.88
38_D	41_R	1.202	0.88
541_S	572_S	1.200	0.87
532_V	543_V	1.192	0.87
128_V	279_Y	1.190	0.87
502_W	535_L	1.181	0.87
306_V	314_V	1.180	0.87
452_H	480_D	1.177	0.86
139_L	297_V	1.175	0.86
392_R	416_L	1.170	0.86
381_A	404_E	1.169	0.86
37_N	41_R	1.169	0.86
513_R	544_T	1.169	0.86
533_Y	567_Y	1.165	0.86
76_G	108_K	1.160	0.86
198_A	256_L	1.159	0.86
521_H	550_S	1.159	0.86
30_S	33_G	1.158	0.86
413_R	456_S	1.157	0.85
55_A	72_I	1.151	0.85
412_V	415_C	1.140	0.85
49_T	85_V	1.140	0.85
425_L	455_I	1.137	0.84
93_G	98_P	1.137	0.84
33_G	37_N	1.128	0.84
387_D	411_V	1.127	0.84
464_G	492_P	1.127	0.84
489_C	520_H	1.123	0.84
141_F	297_V	1.123	0.84
493_Y	526_M	1.121	0.84
493_Y	533_Y	1.120	0.84
111_L	303_L	1.119	0.84
547_C	581_W	1.114	0.83
198_A	259_A	1.112	0.83
388_F	401_L	1.111	0.83
27_I	50_S	1.110	0.83
109_V	323_T	1.108	0.83
154_A	263_L	1.107	0.83
380_V	388_F	1.104	0.83
147_N	291_A	1.104	0.83
291_A	295_V	1.096	0.82
500_W	535_L	1.094	0.82
34_N	37_N	1.091	0.82
80_A	114_G	1.085	0.82
380_V	410_G	1.080	0.81
149_K	283_R	1.079	0.81
29_I	39_G	1.077	0.81
323_T	394_D	1.075	0.81
393_F	400_G	1.068	0.81
194_K	261_E	1.065	0.80
324_F	378_V	1.063	0.80
155_R	158_E	1.061	0.80
69_G	97_S	1.061	0.80
117_I	297_V	1.055	0.80
48_L	111_L	1.051	0.79
378_V	388_F	1.048	0.79
227_F	231_E	1.047	0.79
408_Q	451_A	1.043	0.79
201_V	210_N	1.041	0.79
215_S	226_R	1.041	0.79
35_D	38_D	1.040	0.79
69_G	96_D	1.036	0.78
52_L	85_V	1.035	0.78
59_R	66_V	1.035	0.78
44_P	47_T	1.032	0.78
427_V	453_Q	1.029	0.78
488_I	519_I	1.028	0.78
520_H	549_H	1.027	0.78
144_L	297_V	1.023	0.78
59_R	99_T	1.022	0.78
150_K	465_N	1.017	0.77
146_V	280_Y	1.017	0.77
73_C	107_E	1.013	0.77
30_S	44_P	1.013	0.77
390_R	414_G	1.009	0.77
227_F	232_S	1.008	0.77
86_F	305_Q	1.008	0.77
518_L	547_C	1.007	0.76
341_Q	369_G	1.007	0.76
55_A	101_I	1.005	0.76
28_W	104_V	1.005	0.76
388_F	393_F	1.004	0.76
52_L	55_A	1.004	0.76
420_I	423_N	1.003	0.76
35_D	45_K	1.002	0.76
195_A	198_A	1.000	0.76
572_S	575_I	0.999	0.76
461_T	489_C	0.999	0.76
153_R	258_N	0.999	0.76
66_V	69_G	0.998	0.76
457_N	485_H	0.996	0.76
33_G	50_S	0.994	0.76
493_Y	529_V	0.991	0.75
304_I	324_F	0.990	0.75
41_R	75_E	0.988	0.75
81_L	85_V	0.988	0.75
396_L	420_I	0.985	0.75
109_V	322_I	0.982	0.75
455_I	458_C	0.979	0.74
388_F	391_C	0.978	0.74
146_V	295_V	0.978	0.74
459_Y	487_E	0.975	0.74
267_G	282_P	0.970	0.74
72_I	99_T	0.969	0.74
122_K	127_W	0.966	0.73
131_V	278_V	0.966	0.73
421_A	466_E	0.965	0.73
192_A	256_L	0.965	0.73
210_N	257_T	0.965	0.73
319_F	322_I	0.963	0.73
95_E	316_H	0.956	0.73
303_L	377_A	0.944	0.72
304_I	319_F	0.943	0.72
534_T	572_S	0.943	0.72
472_A	491_V	0.942	0.72
195_A	261_E	0.940	0.71
154_A	158_E	0.939	0.71
141_F	278_V	0.937	0.71
106_D	109_V	0.930	0.71
487_E	521_H	0.923	0.70
84_P	299_A	0.918	0.70
454_Q	484_E	0.918	0.70
151_A	283_R	0.916	0.69
471_L	493_Y	0.911	0.69
320_E	390_R	0.910	0.69
307_K	381_A	0.908	0.69
158_E	265_V	0.907	0.69
228_H	231_E	0.904	0.68
396_L	417_F	0.901	0.68
517_N	546_N	0.899	0.68
39_G	45_K	0.897	0.68
55_A	99_T	0.896	0.68
110_V	325_S	0.896	0.68
384_N	408_Q	0.894	0.67
180_A	183_I	0.892	0.67
192_A	261_E	0.892	0.67
549_H	583_E	0.892	0.67
153_R	199_E	0.884	0.67
155_R	264_D	0.882	0.66
125_K	281_Y	0.882	0.66
496_I	532_V	0.876	0.66
490_E	524_K	0.876	0.66
78_T	378_V	0.870	0.65
303_L	327_T	0.863	0.65
56_R	87_I	0.863	0.65
76_G	106_D	0.861	0.65
475_A	481_I	0.860	0.64
454_Q	482_N	0.856	0.64
73_C	103_P	0.854	0.64
37_N	45_K	0.853	0.64
30_S	75_E	0.847	0.63
33_G	46_A	0.846	0.63
50_S	53_R	0.845	0.63
386_I	410_G	0.845	0.63
41_R	104_V	0.845	0.63
26_E	71_T	0.844	0.63
256_L	262_L	0.841	0.63
127_W	288_L	0.840	0.63
267_G	286_E	0.838	0.62
543_V	568_T	0.836	0.62
309_T	313_P	0.831	0.62
28_W	68_G	0.829	0.62
84_P	302_T	0.826	0.61
201_V	255_Y	0.825	0.61
83_E	86_F	0.824	0.61
152_V	264_D	0.822	0.61
535_L	570_E	0.822	0.61
534_T	575_I	0.820	0.61
376_A	402_D	0.820	0.61
327_T	396_L	0.820	0.61
144_L	280_Y	0.820	0.61
400_G	423_N	0.820	0.61
403_Y	415_C	0.820	0.61
66_V	95_E	0.816	0.60
425_L	460_F	0.814	0.60
59_R	64_E	0.812	0.60
131_V	139_L	0.811	0.60
418_R	461_T	0.810	0.60
380_V	407_V	0.809	0.60
497_S	502_W	0.809	0.60
156_D	264_D	0.808	0.60
521_H	549_H	0.807	0.59
472_A	495_G	0.806	0.59
568_T	590_N	0.803	0.59
462_E	465_N	0.801	0.59
24_A	68_G	0.795	0.58
313_P	382_A	0.795	0.58
151_A	286_E	0.793	0.58
123_Q	260_R	0.793	0.58
74_M	85_V	0.791	0.58
111_L	324_F	0.791	0.58
217_E	223_A	0.790	0.58
240_W	246_T	0.786	0.57
148_G	294_E	0.786	0.57
47_T	50_S	0.786	0.57
482_N	515_H	0.783	0.57
227_F	230_P	0.782	0.57
44_P	51_A	0.782	0.57
112_S	296_I	0.782	0.57
150_K	395_H	0.780	0.57
496_I	514_V	0.780	0.57
399_T	422_G	0.779	0.57
258_N	303_L	0.778	0.57
211_L	231_E	0.778	0.57
397_G	421_A	0.777	0.57
35_D	40_T	0.775	0.56
540_K	546_N	0.774	0.56
29_I	45_K	0.774	0.56
547_C	583_E	0.772	0.56
477_Y	501_G	0.768	0.56
59_R	65_R	0.767	0.56
126_L	260_R	0.764	0.55
303_L	324_F	0.763	0.55
152_V	268_E	0.761	0.55
476_G	500_W	0.760	0.55
80_A	116_R	0.760	0.55
326_H	395_H	0.758	0.55
117_I	271_H	0.757	0.55
482_N	513_R	0.756	0.55
548_V	551_I	0.754	0.54
74_M	79_Y	0.753	0.54
296_I	326_H	0.752	0.54
123_Q	128_V	0.751	0.54
513_R	542_Y	0.748	0.54
133_M	139_L	0.748	0.54
534_T	538_Q	0.748	0.54
126_L	281_Y	0.746	0.54
141_F	298_P	0.745	0.53
260_R	281_Y	0.744	0.53
499_G	533_Y	0.743	0.53
394_D	418_R	0.742	0.53
261_E	270_Y	0.741	0.53
325_S	392_R	0.740	0.53
316_H	409_G	0.740	0.53
120_W	278_V	0.740	0.53
532_V	548_V	0.739	0.53
232_S	235_Q	0.738	0.53
102_R	321_K	0.738	0.53
389_E	413_R	0.737	0.53
309_T	314_V	0.736	0.53
111_L	319_F	0.734	0.52
481_I	512_N	0.731	0.52
178_V	181_V	0.731	0.52
461_T	490_E	0.731	0.52
131_V	271_H	0.728	0.52
460_F	472_A	0.728	0.52
416_L	459_Y	0.727	0.52
515_H	542_Y	0.726	0.52
479_K	510_R	0.725	0.51
565_Y	582_T	0.725	0.51
428_G	533_Y	0.723	0.51
56_R	101_I	0.722	0.51
499_G	570_E	0.721	0.51
121_K	130_D	0.719	0.51
194_K	197_Y	0.718	0.51
502_W	570_E	0.716	0.51
92_S	99_T	0.713	0.50
52_L	319_F	0.712	0.50
86_F	307_K	0.711	0.50
400_G	417_F	0.709	0.50
315_S	385_Q	0.709	0.50
134_F	276_R	0.708	0.50
156_D	268_E	0.707	0.50
540_K	551_I	0.703	0.49
108_K	321_K	0.702	0.49
89_P	314_V	0.702	0.49
499_G	571_G	0.701	0.49
581_W	602_G	0.701	0.49
460_F	463_V	0.699	0.49
79_Y	111_L	0.698	0.49
499_G	535_L	0.698	0.49
393_F	401_L	0.697	0.49
310_F	382_A	0.696	0.49
427_V	483_I	0.696	0.49
87_I	306_V	0.695	0.48
141_F	328_T	0.694	0.48
577_V	598_W	0.694	0.48
256_L	259_A	0.692	0.48
152_V	265_V	0.691	0.48
231_E	235_Q	0.690	0.48
543_V	546_N	0.690	0.48
85_V	300_I	0.687	0.48
145_W	326_H	0.686	0.48
42_P	45_K	0.685	0.47
92_S	98_P	0.682	0.47
111_L	322_I	0.682	0.47
543_V	566_L	0.682	0.47
407_V	453_Q	0.680	0.47
290_D	460_F	0.679	0.47
200_M	256_L	0.678	0.47
125_K	282_P	0.677	0.47
198_A	202_L	0.676	0.47
499_G	502_W	0.676	0.47
544_T	547_C	0.675	0.46
143_Q	332_P	0.674	0.46
132_P	276_R	0.673	0.46
497_S	500_W	0.672	0.46
69_G	100_V	0.671	0.46
534_T	543_V	0.670	0.46
152_V	155_R	0.670	0.46
131_V	134_F	0.669	0.46
464_G	470_C	0.669	0.46
83_E	111_L	0.668	0.46
403_Y	412_V	0.668	0.46
69_G	95_E	0.667	0.46
155_R	492_P	0.666	0.46
538_Q	575_I	0.665	0.46
254_F	514_V	0.665	0.46
58_W	70_I	0.664	0.45
476_G	499_G	0.663	0.45
403_Y	407_V	0.662	0.45
388_F	417_F	0.661	0.45
543_V	548_V	0.660	0.45
497_S	535_L	0.660	0.45
147_N	290_D	0.660	0.45
73_C	105_A	0.659	0.45
513_R	545_E	0.659	0.45
541_S	570_E	0.659	0.45
209_A	232_S	0.659	0.45
280_Y	298_P	0.658	0.45
486_N	546_N	0.658	0.45
512_N	541_S	0.657	0.45
306_V	319_F	0.656	0.45
66_V	96_D	0.655	0.45
378_V	386_I	0.654	0.44
255_Y	468_W	0.653	0.44
193_L	272_D	0.653	0.44
498_L	512_N	0.653	0.44
37_N	44_P	0.653	0.44
178_V	182_A	0.652	0.44
542_Y	548_V	0.651	0.44
502_W	541_S	0.650	0.44
484_E	544_T	0.649	0.44
130_D	275_A	0.648	0.44
228_H	234_I	0.644	0.43
523_A	564_F	0.644	0.43
381_A	405_E	0.641	0.43
120_W	288_L	0.640	0.43
475_A	498_L	0.639	0.43
72_I	91_D	0.639	0.43
488_I	567_Y	0.638	0.43
522_Y	529_V	0.636	0.43
471_L	494_S	0.635	0.43
129_A	278_V	0.634	0.42
96_D	99_T	0.634	0.42
139_L	276_R	0.634	0.42
213_I	565_Y	0.633	0.42
522_Y	551_I	0.632	0.42
399_T	426_V	0.630	0.42
39_G	46_A	0.629	0.42
453_Q	540_K	0.628	0.42
329_W	467_D	0.626	0.42
141_F	153_R	0.625	0.42
401_L	415_C	0.624	0.42
48_L	101_I	0.624	0.42
33_G	44_P	0.624	0.42
93_G	99_T	0.624	0.42
40_T	44_P	0.623	0.41
130_D	276_R	0.623	0.41
204_Q	209_A	0.622	0.41
376_A	379_S	0.621	0.41
484_E	542_Y	0.618	0.41
415_C	486_N	0.617	0.41
565_Y	585_E	0.617	0.41
157_V	160_F	0.617	0.41
535_L	571_G	0.616	0.41
419_D	462_E	0.616	0.41
469_G	493_Y	0.615	0.41
488_I	495_G	0.614	0.41
455_I	483_I	0.613	0.40
56_R	322_I	0.612	0.40
545_E	578_R	0.612	0.40
477_Y	508_C	0.611	0.40
200_M	301_E	0.609	0.40
561_N	564_F	0.609	0.40
31_P	75_E	0.606	0.40
419_D	465_N	0.606	0.40
34_N	67_R	0.606	0.40
180_A	184_R	0.606	0.40
311_D	447_R	0.606	0.40
534_T	541_S	0.605	0.40
412_V	417_F	0.604	0.40
546_N	580_N	0.604	0.40
394_D	514_V	0.604	0.40
472_A	488_I	0.604	0.40
156_D	262_L	0.604	0.40
413_R	457_N	0.600	0.39
121_K	320_E	0.600	0.39
310_F	448_E	0.600	0.39
132_P	455_I	0.599	0.39
34_N	39_G	0.595	0.39
453_Q	458_C	0.595	0.39
421_A	467_D	0.594	0.39
75_E	103_P	0.594	0.39
515_H	545_E	0.593	0.39
134_F	425_L	0.592	0.38
91_D	114_G	0.591	0.38
32_Q	75_E	0.591	0.38
485_H	600_N	0.589	0.38
501_G	592_N	0.588	0.38
79_Y	109_V	0.587	0.38
109_V	464_G	0.586	0.38
401_L	425_L	0.586	0.38
24_A	225_I	0.585	0.38
593_G	601_N	0.584	0.38
494_S	533_Y	0.582	0.38
102_R	389_E	0.582	0.38
103_P	108_K	0.581	0.37
176_L	182_A	0.581	0.37
33_G	47_T	0.581	0.37
115_I	139_L	0.581	0.37
421_A	596_N	0.581	0.37
70_I	99_T	0.579	0.37
265_V	281_Y	0.577	0.37
59_R	101_I	0.577	0.37
538_Q	541_S	0.575	0.37
591_A	596_N	0.575	0.37
111_L	304_I	0.575	0.37
521_H	552_Y	0.575	0.37
93_G	96_D	0.575	0.37
46_A	74_M	0.574	0.37
423_N	426_V	0.573	0.37
271_H	297_V	0.572	0.37
175_I	179_P	0.572	0.37
59_R	97_S	0.571	0.37
80_A	326_H	0.571	0.37
420_I	424_G	0.571	0.37
37_N	46_A	0.569	0.36
34_N	452_H	0.569	0.36
401_L	412_V	0.568	0.36
131_V	279_Y	0.568	0.36
24_A	400_G	0.568	0.36
460_F	473_I	0.568	0.36
252_S	531_G	0.567	0.36
324_F	425_L	0.567	0.36
519_I	588_L	0.567	0.36
542_Y	578_R	0.566	0.36
300_I	304_I	0.566	0.36
484_E	513_R	0.566	0.36
145_W	253_A	0.566	0.36
91_D	319_F	0.565	0.36
494_S	497_S	0.565	0.36
488_I	497_S	0.564	0.36
327_T	377_A	0.564	0.36
337_H	340_L	0.564	0.36
570_E	591_A	0.563	0.36
468_W	526_M	0.563	0.36
66_V	99_T	0.562	0.36
386_I	453_Q	0.562	0.36
85_V	513_R	0.561	0.36
570_E	592_N	0.561	0.36
56_R	92_S	0.561	0.36
535_L	541_S	0.560	0.35
425_L	496_I	0.560	0.35
155_R	268_E	0.560	0.35
194_K	274_D	0.559	0.35
131_V	437_T	0.559	0.35
117_I	125_K	0.558	0.35
55_A	417_F	0.558	0.35
29_I	44_P	0.558	0.35
143_Q	328_T	0.557	0.35
205_M	253_A	0.557	0.35
110_V	220_G	0.557	0.35
231_E	234_I	0.556	0.35
56_R	90_E	0.556	0.35
405_E	429_S	0.555	0.35
75_E	102_R	0.554	0.35
568_T	596_N	0.554	0.35
89_P	124_G	0.553	0.35
203_H	255_Y	0.553	0.35
514_V	532_V	0.553	0.35
93_G	100_V	0.552	0.35
30_S	35_D	0.552	0.35
42_P	75_E	0.552	0.35
535_L	572_S	0.550	0.35
267_G	280_Y	0.550	0.35
391_C	458_C	0.549	0.35
110_V	129_A	0.549	0.35
593_G	596_N	0.548	0.34
376_A	412_V	0.548	0.34
25_G	34_N	0.548	0.34
310_F	313_P	0.548	0.34
94_T	97_S	0.548	0.34
143_Q	269_W	0.548	0.34
126_L	279_Y	0.547	0.34
48_L	52_L	0.546	0.34
553_K	563_W	0.546	0.34
121_K	277_K	0.545	0.34
199_E	210_N	0.545	0.34
143_Q	150_K	0.545	0.34
116_R	129_A	0.544	0.34
546_N	549_H	0.544	0.34
517_N	580_N	0.543	0.34
500_W	512_N	0.543	0.34
24_A	27_I	0.543	0.34
102_R	200_M	0.542	0.34
47_T	393_F	0.542	0.34
42_P	54_Q	0.542	0.34
529_V	592_N	0.542	0.34
128_V	275_A	0.542	0.34
27_I	75_E	0.541	0.34
493_Y	567_Y	0.540	0.34
113_G	327_T	0.540	0.34
194_K	198_A	0.539	0.34
155_R	257_T	0.539	0.34
475_A	499_G	0.539	0.34
263_L	270_Y	0.539	0.34
571_G	592_N	0.538	0.34
51_A	79_Y	0.538	0.34
117_I	215_S	0.538	0.34
375_A	398_S	0.537	0.33
496_I	518_L	0.537	0.33
529_V	564_F	0.536	0.33
544_T	579_D	0.536	0.33
378_V	460_F	0.536	0.33
163_M	166_I	0.534	0.33
324_F	396_L	0.534	0.33
267_G	283_R	0.534	0.33
579_D	600_N	0.533	0.33
36_L	452_H	0.533	0.33
168_S	171_E	0.532	0.33
422_G	573_S	0.532	0.33
197_Y	203_H	0.532	0.33
27_I	30_S	0.531	0.33
27_I	73_C	0.531	0.33
266_A	282_P	0.530	0.33
471_L	497_S	0.530	0.33
39_G	51_A	0.530	0.33
164_N	167_C	0.530	0.33
403_Y	427_V	0.529	0.33
428_G	474_L	0.529	0.33
602_G	605_V	0.528	0.33
114_G	395_H	0.528	0.33
256_L	534_T	0.527	0.33
123_Q	279_Y	0.527	0.33
527_Y	564_F	0.527	0.33
81_L	303_L	0.526	0.32
127_W	289_Q	0.526	0.32
193_L	198_A	0.526	0.32
469_G	497_S	0.525	0.32
306_V	322_I	0.525	0.32
255_Y	268_E	0.524	0.32
532_V	575_I	0.524	0.32
495_G	561_N	0.524	0.32
134_F	140_D	0.523	0.32
142_R	153_R	0.521	0.32
146_V	291_A	0.521	0.32
146_V	285_G	0.521	0.32
145_W	509_M	0.521	0.32
179_P	182_A	0.520	0.32
111_L	305_Q	0.520	0.32
124_G	281_Y	0.520	0.32
478_V	509_M	0.520	0.32
47_T	72_I	0.520	0.32
317_I	474_L	0.520	0.32
32_Q	43_S	0.519	0.32
603_P	606_D	0.519	0.32
124_G	295_V	0.518	0.32
319_F	531_G	0.518	0.32
529_V	571_G	0.517	0.32
30_S	322_I	0.517	0.32
493_Y	538_Q	0.517	0.32
528_D	567_Y	0.516	0.32
374_P	398_S	0.516	0.32
262_L	522_Y	0.516	0.32
205_M	527_Y	0.516	0.32
454_Q	495_G	0.515	0.32
512_N	538_Q	0.515	0.32
30_S	54_Q	0.515	0.32
393_F	483_I	0.515	0.32
425_L	458_C	0.514	0.31
568_T	571_G	0.514	0.31
258_N	480_D	0.514	0.31
192_A	259_A	0.514	0.31
493_Y	570_E	0.514	0.31
86_F	488_I	0.514	0.31
209_A	233_R	0.512	0.31
214_R	228_H	0.511	0.31
516_A	600_N	0.511	0.31
576_T	597_V	0.510	0.31
428_G	499_G	0.510	0.31
34_N	72_I	0.509	0.31
215_S	424_G	0.508	0.31
473_I	483_I	0.507	0.31
111_L	224_A	0.507	0.31
131_V	141_F	0.506	0.31
504_Q	592_N	0.506	0.31
267_G	462_E	0.505	0.31
429_S	433_A	0.504	0.31
306_V	317_I	0.504	0.31
530_A	563_W	0.504	0.31
533_Y	571_G	0.503	0.31
423_N	465_N	0.503	0.31
38_D	44_P	0.503	0.31
140_D	452_H	0.502	0.30
598_W	603_P	0.502	0.30
280_Y	288_L	0.501	0.30
553_K	586_K	0.501	0.30
113_G	530_A	0.501	0.30
502_W	571_G	0.500	0.30
431_S	477_Y	0.500	0.30

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3vsv_A	1	0.6891	100	0.614	Contact Map
1ru4_A	1	0.516	99.9	0.831	Contact Map
1dbg_A	1	0.5369	99.9	0.856	Contact Map
4nk6_A	1	0.0529	99.7	0.879	Contact Map
2pyg_A	1	0.5321	99.7	0.887	Contact Map
2inu_A	1	0.5	99.4	0.902	Contact Map
3jur_A	1	0.6843	99.4	0.904	Contact Map
4mr0_A	1	0.6026	99.3	0.908	Contact Map
4ru5_A	1	0.7003	99	0.92	Contact Map
3gq8_A	1	0.6635	98.8	0.927	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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