GREMLIN Database
T0895_1_129 - T0895 1-129
ID: 45 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 129 (111)
Sequences: 98 (86)
Seq/√Len: 8.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
69_V116_L3.6770.96
22_Y69_V2.3230.71
16_G112_V2.2990.70
42_K84_I2.2440.68
60_Y85_V2.2280.67
52_C68_G2.1690.65
33_L102_L2.1450.64
109_T112_V2.1420.64
34_D38_N2.1210.63
109_T114_K2.0500.61
54_F76_P2.0440.60
24_D44_S2.0410.60
55_P68_G2.0020.59
62_E84_I1.9910.58
86_S89_T1.9130.55
22_Y76_P1.8220.51
29_E32_F1.8050.51
23_F71_F1.7480.48
48_D74_G1.7180.47
52_C84_I1.6450.44
59_S87_E1.6450.44
55_P65_H1.5900.42
44_S54_F1.5890.42
62_E79_E1.5560.40
64_E99_E1.5330.39
71_F85_V1.4860.38
41_N114_K1.4510.36
32_F42_K1.4120.35
65_H105_H1.4010.34
28_N91_F1.3250.32
36_V119_I1.3140.31
92_E109_T1.2810.30
22_Y35_A1.2690.30
56_D123_G1.2420.29
39_I45_Y1.2370.29
71_F105_H1.1990.27
115_L119_I1.1930.27
39_I112_V1.1830.27
26_M56_D1.1690.26
111_K115_L1.1660.26
80_D84_I1.1600.26
110_E114_K1.1380.25
49_G105_H1.1380.25
19_I38_N1.1300.25
33_L38_N1.1290.25
19_I35_A1.1150.25
102_L106_P1.1130.25
94_V104_L1.1130.25
23_F91_F1.1120.24
19_I118_K1.0950.24
41_N88_E1.0830.24
57_M94_V1.0520.23
13_S96_L1.0190.22
94_V113_N1.0140.22
23_F67_E1.0050.21
13_S69_V1.0040.21
107_E121_S1.0010.21
26_M67_E0.9960.21
12_R16_G0.9830.21
99_E105_H0.9820.21
30_N39_I0.9670.20
80_D105_H0.9630.20
38_N41_N0.9460.20
99_E104_L0.9360.19
88_E92_E0.9320.19
13_S41_N0.9300.19
34_D47_L0.9280.19
17_W103_Q0.9090.19
23_F107_E0.9090.19
66_F97_A0.9090.19
30_N63_S0.9010.19
37_E45_Y0.9000.19
48_D64_E0.8990.19
40_V91_F0.8970.18
28_N63_S0.8890.18
17_W30_N0.8850.18
24_D73_V0.8840.18
102_L108_D0.8800.18
36_V39_I0.8780.18
50_I57_M0.8740.18
33_L67_E0.8740.18
24_D107_E0.8640.18
30_N45_Y0.8560.17
87_E122_A0.8490.17
84_I101_Y0.8380.17
61_D73_V0.8330.17
45_Y54_F0.8230.17
86_S117_S0.8220.17
90_C94_V0.8060.16
12_R117_S0.8040.16
26_M90_C0.7970.16
13_S110_E0.7920.16
19_I44_S0.7860.16
69_V90_C0.7830.16
30_N35_A0.7750.16
96_L120_P0.7730.16
115_L121_S0.7690.16
40_V45_Y0.7690.16
74_G77_P0.7650.15
120_P123_G0.7470.15
36_V114_K0.7430.15
39_I55_P0.7380.15
52_C101_Y0.7370.15
32_F66_F0.7310.15
39_I69_V0.7230.15
18_T77_P0.7190.14
23_F83_V0.7170.14
13_S83_V0.7120.14
15_P90_C0.7070.14
56_D67_E0.7030.14
71_F107_E0.7020.14
36_V70_E0.7020.14
26_M91_F0.7000.14
42_K99_E0.6990.14
68_G84_I0.6940.14
34_D92_E0.6920.14
46_I54_F0.6870.14
24_D61_D0.6870.14
95_R123_G0.6830.14
35_A43_E0.6720.14
36_V45_Y0.6680.13
60_Y106_P0.6660.13
86_S93_Y0.6630.13
30_N83_V0.6590.13
55_P71_F0.6590.13
23_F55_P0.6510.13
111_K119_I0.6440.13
34_D102_L0.6320.13
55_P66_F0.6290.13
39_I71_F0.6280.13
51_Y72_A0.6270.13
100_K121_S0.6140.12
13_S112_V0.6120.12
17_W76_P0.6100.12
14_E20_R0.6070.12
49_G59_S0.6040.12
64_E74_G0.6040.12
50_I76_P0.6030.12
47_L50_I0.6020.12
31_R47_L0.6020.12
68_G87_E0.6010.12
100_K123_G0.5990.12
47_L93_Y0.5920.12
104_L113_N0.5880.12
59_S112_V0.5820.12
97_A106_P0.5800.12
20_R83_V0.5660.12
90_C112_V0.5640.12
76_P86_S0.5570.11
113_N118_K0.5510.11
66_F95_R0.5470.11
42_K88_E0.5470.11
48_D122_A0.5460.11
107_E123_G0.5450.11
32_F71_F0.5410.11
22_Y88_E0.5310.11
88_E93_Y0.5270.11
79_E88_E0.5230.11
102_L113_N0.5230.11
15_P20_R0.5190.11
52_C55_P0.5190.11
84_I119_I0.5170.11
63_S113_N0.5070.11
55_P67_E0.5070.11
43_E47_L0.5050.11
28_N100_K0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4q7o_A 1 0.9147 41.1 0.91 Contact Map
2guk_A 1 0.5736 7.4 0.936 Contact Map
2jul_A 1 0.3333 3.8 0.945 Contact Map
1zvd_A 1 0.2946 3.5 0.945 Contact Map
3dd4_A 1 0.3333 3.3 0.946 Contact Map
1s6c_A 1 0.0155 3 0.947 Contact Map
4b8r_A 1 0.7054 2.5 0.949 Contact Map
4guk_A 1 0.3333 2.5 0.95 Contact Map
1goi_A 1 0.8837 2.5 0.95 Contact Map
1fpw_A 1 0.3333 2.4 0.95 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0047 seconds.