GREMLIN Database
T0884_1_75 - T0884 1-75
ID: 31 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 75 (65)
Sequences: 202 (138)
Seq/√Len: 17.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
35_V49_R4.5081.00
3_P46_G2.8930.98
7_Q13_S2.8460.98
13_S58_M2.8200.98
47_H60_N2.4560.95
21_P28_P2.2510.92
6_G9_V1.8500.82
69_D73_N1.5860.71
50_A56_S1.5710.70
4_S46_G1.4740.65
10_L60_N1.4630.65
59_Q68_V1.4210.62
51_W68_V1.3630.59
37_D47_H1.3160.56
24_V37_D1.3130.56
7_Q58_M1.2850.54
36_F60_N1.2700.53
23_R27_D1.2440.52
54_L74_P1.2200.50
70_R75_K1.2110.50
11_E73_N1.2000.49
62_L65_G1.1540.46
52_K59_Q1.1420.46
61_A68_V1.1210.45
70_R73_N1.1100.44
15_Q23_R1.0850.42
5_N46_G1.0420.40
28_P31_G1.0230.39
4_S15_Q1.0220.39
17_K53_D1.0120.38
52_K68_V0.9850.37
31_G69_D0.9850.37
18_E34_V0.9840.37
10_L35_V0.9820.37
26_V52_K0.9810.36
18_E31_G0.9620.35
18_E29_Q0.9580.35
34_V67_Y0.9540.35
30_T56_S0.9420.34
47_H65_G0.9380.34
50_A59_Q0.9150.33
30_T59_Q0.8820.31
46_G67_Y0.8800.31
33_F52_K0.8720.31
9_V57_D0.8690.30
10_L15_Q0.8650.30
31_G60_N0.8550.30
29_Q58_M0.8290.28
23_R46_G0.8200.28
15_Q18_E0.8100.28
28_P65_G0.8080.27
36_F63_V0.8000.27
23_R53_D0.7800.26
50_A61_A0.7800.26
71_K74_P0.7770.26
23_R47_H0.7510.25
33_F50_A0.7480.25
30_T68_V0.7450.25
51_W59_Q0.7440.25
54_L67_Y0.7430.24
16_V54_L0.7240.24
10_L47_H0.7180.23
50_A68_V0.7150.23
28_P33_F0.7040.23
15_Q20_S0.7030.23
2_G46_G0.6940.22
21_P29_Q0.6770.22
20_S61_A0.6720.21
19_T61_A0.6720.21
32_E71_K0.6690.21
16_V70_R0.6670.21
11_E35_V0.6620.21
7_Q11_E0.6530.21
33_F59_Q0.6510.21
33_F68_V0.6430.20
26_V32_E0.6380.20
30_T33_F0.6320.20
68_V71_K0.6320.20
17_K24_V0.6280.20
7_Q10_L0.6200.19
53_D58_M0.6190.19
23_R37_D0.6150.19
31_G47_H0.6110.19
18_E37_D0.6080.19
9_V23_R0.6060.19
67_Y70_R0.6040.19
55_T66_G0.6020.19
29_Q48_V0.5940.18
17_K62_L0.5930.18
48_V66_G0.5930.18
55_T68_V0.5880.18
29_Q60_N0.5780.18
27_D36_F0.5700.18
30_T58_M0.5470.17
11_E69_D0.5360.16
51_W72_G0.5290.16
30_T71_K0.5150.16
31_G62_L0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2b5u_A 1 0.88 99.7 0.343 Contact Map
2fhz_B 1 0.84 99.3 0.499 Contact Map
3jb9_S 1 0.5867 5.9 0.914 Contact Map
1vyk_A 1 0.64 3.4 0.924 Contact Map
2o55_A 1 0.8133 3.2 0.924 Contact Map
3mz2_A 1 0.96 3.1 0.925 Contact Map
3luu_A 1 0.5333 3 0.925 Contact Map
3i10_A 1 0.96 3 0.925 Contact Map
2pz0_A 1 0.92 2.9 0.926 Contact Map
3nuh_B 1 0.6 2.9 0.926 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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