GREMLIN Database
T0937_230-369_1_140 - T0937_230-369 1-140
ID: 127 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 140 (125)
Sequences: 640 (409)
Seq/√Len: 36.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
44_D89_T3.8381.00
83_N87_G3.6911.00
39_E132_K3.6181.00
83_N89_T3.1701.00
38_D95_T2.9431.00
38_D132_K2.8751.00
44_D129_R2.8081.00
36_A39_E2.7871.00
60_N64_E2.6831.00
36_A109_R2.1690.99
23_D26_I2.0660.99
43_I92_V2.0130.99
58_L92_V1.9770.98
40_A91_I1.9510.98
34_S110_T1.9490.98
75_V79_S1.9390.98
40_A131_V1.9190.98
97_P102_W1.8930.98
40_A93_A1.8380.97
44_D87_G1.7390.96
35_L130_V1.6380.95
50_D121_A1.5200.92
33_W66_L1.5070.92
98_G102_W1.5000.92
26_I118_V1.4970.92
22_G57_Q1.4660.91
72_D75_V1.3880.88
41_L111_G1.3870.88
74_C79_S1.3670.88
57_Q65_S1.3600.87
33_W111_G1.3340.86
30_H55_N1.3250.86
37_A109_R1.3240.86
58_L104_D1.3160.86
20_V23_D1.2880.84
56_V113_I1.2740.84
37_A95_T1.2400.82
90_V103_L1.2310.81
31_S92_V1.2240.81
128_T133_L1.2180.81
82_P88_V1.1710.78
40_A99_S1.1640.78
91_I101_N1.1630.78
91_I99_S1.1410.76
27_Y93_A1.1370.76
94_A105_T1.1350.76
39_E94_A1.1320.76
46_D87_G1.1300.75
93_A129_R1.0900.73
97_P107_G1.0850.72
95_T133_L1.0800.72
44_D47_T1.0780.72
67_D114_C1.0590.71
96_R102_W1.0480.70
94_A133_L1.0450.70
47_T62_W1.0340.69
28_Y118_V1.0340.69
80_A90_V1.0290.68
37_A94_A1.0140.67
45_V80_A0.9880.65
52_D119_G0.9670.63
23_D118_V0.9560.63
25_N65_S0.9420.61
36_A95_T0.9410.61
34_S93_A0.9230.60
8_A128_T0.9210.60
41_L130_V0.9090.59
26_I64_E0.9060.58
7_N41_L0.9040.58
28_Y64_E0.9030.58
27_Y63_M0.8950.57
75_V101_N0.8830.56
55_N58_L0.8820.56
96_R124_V0.8800.56
91_I97_P0.8700.55
17_C20_V0.8670.55
9_L22_G0.8670.55
75_V90_V0.8660.55
17_C23_D0.8630.55
76_N79_S0.8630.55
34_S109_R0.8610.54
74_C113_I0.8590.54
40_A133_L0.8450.53
53_F119_G0.8380.52
26_I30_H0.8370.52
65_S114_C0.8350.52
112_T117_W0.8340.52
52_D110_T0.8270.51
89_T99_S0.8230.51
25_N118_V0.8220.51
25_N28_Y0.8210.51
6_V32_C0.8190.51
32_C61_Y0.8180.51
39_E130_V0.8170.51
10_P92_V0.7870.48
54_W80_A0.7820.48
126_P129_R0.7810.47
56_V75_V0.7800.47
92_V122_Q0.7700.46
33_W79_S0.7690.46
56_V92_V0.7640.46
26_I62_W0.7510.45
17_C21_G0.7480.45
60_N108_H0.7460.44
42_V131_V0.7450.44
55_N114_C0.7430.44
9_L31_S0.7410.44
56_V103_L0.7400.44
38_D85_D0.7390.44
43_I56_V0.7390.44
63_M73_I0.7360.44
5_H8_A0.7130.42
20_V55_N0.7100.41
84_A95_T0.7090.41
84_A87_G0.7060.41
51_C73_I0.7040.41
7_N105_T0.7010.41
81_R132_K0.6980.40
42_V91_I0.6900.40
46_D95_T0.6860.39
73_I85_D0.6820.39
21_G57_Q0.6820.39
82_P118_V0.6810.39
94_A107_G0.6790.39
51_C63_M0.6770.39
18_Q21_G0.6750.38
61_Y65_S0.6750.38
19_S103_L0.6730.38
14_Q73_I0.6640.37
93_A133_L0.6640.37
24_P51_C0.6600.37
24_P69_R0.6580.37
32_C110_T0.6570.37
122_Q129_R0.6550.37
45_V88_V0.6530.37
26_I57_Q0.6470.36
75_V81_R0.6450.36
65_S73_I0.6410.36
33_W56_V0.6400.36
60_N63_M0.6380.35
129_R132_K0.6370.35
26_I66_L0.6310.35
73_I103_L0.6270.34
67_D101_N0.6250.34
40_A78_H0.6200.34
39_E105_T0.6150.34
22_G68_Y0.6140.33
67_D84_A0.6140.33
77_K110_T0.6120.33
12_A17_C0.6110.33
55_N59_N0.6080.33
14_Q43_I0.6080.33
91_I131_V0.6050.33
72_D90_V0.6010.32
123_P127_R0.5850.31
81_R95_T0.5810.31
94_A129_R0.5770.31
27_Y74_C0.5770.31
10_P13_D0.5660.30
78_H132_K0.5630.30
63_M76_N0.5630.30
28_Y54_W0.5570.29
106_A119_G0.5570.29
67_D70_H0.5560.29
44_D127_R0.5500.29
91_I117_W0.5490.29
28_Y55_N0.5480.29
104_D114_C0.5460.28
35_L128_T0.5390.28
41_L113_I0.5380.28
30_H62_W0.5380.28
76_N115_W0.5370.28
84_A131_V0.5350.28
61_Y110_T0.5320.27
33_W77_K0.5290.27
18_Q23_D0.5230.27
38_D94_A0.5220.27
21_G26_I0.5210.27
35_L105_T0.5170.26
45_V115_W0.5140.26
110_T127_R0.5130.26
74_C103_L0.5060.26
24_P113_I0.5050.26
29_Y115_W0.5050.26
47_T88_V0.5040.25
57_Q60_N0.5020.25
24_P84_A0.5010.25
95_T132_K0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2p3y_A 1 0.9214 98.9 0.75 Contact Map
3u07_A 1 0.9214 97.9 0.817 Contact Map
1u5x_A 1 0.3929 10.6 0.944 Contact Map
1osg_A 1 0.4 6.6 0.949 Contact Map
1tnr_A 1 0.4071 5.1 0.951 Contact Map
4zch_A 1 0.4 5 0.952 Contact Map
1kxg_A 1 0.4 5 0.952 Contact Map
4tq2_A 1 0.55 4.5 0.953 Contact Map
4e0e_A 1 0.4071 4 0.954 Contact Map
3bdr_A 1 0.5429 3.9 0.954 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0054 seconds.