T0942_c90_1_487 - CASP12 - GREMLIN Contacts

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T0942_c90_1_487 - T0942_c90 1-487

ID:	116	Sequences: MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTLSIGQEMQMGDYYVRQLRGSAPLINDPLLTQYINSLGMRLVSHANSVKTPFHFFLINNDEINAFAFFGGNVVLHSALFRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRSAPLTWVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFDPQAMPTFLEKLLDQARYSSRPPEILLTHPLPESRLADARNRANQMRPMVVQSSEDFYLAKARTLGMYNSGRNQLTSDLLDEWAKGNVRQQRAAQYGRALQAMEANKYDEARKTLQPLLAAEPGNAWYLDLATDIDLGQNKANEAINRLKNARDLRTNPVLQLNLANAYLQGGQPQEAANILNRYTFNNKDDSNGWDLLAQAEAALNNRDQELAARAEGYALAGRLDQAISLLSSASSQVKLGSLQQARYDARIDQLRQLQERFKPYTKM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	487 (469)
Sequences:	1681 (1202)
Seq/√Len:	55.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
391_Q	394_E	5.196	1.00
324_K	327_E	5.031	1.00
434_A	450_L	4.931	1.00
194_I	197_T	4.805	1.00
125_D	228_K	4.764	1.00
272_E	276_L	4.750	1.00
358_K	361_E	4.430	1.00
382_L	386_Y	3.825	1.00
293_T	297_L	3.624	1.00
435_E	470_R	3.586	1.00
191_Q	195_S	3.398	1.00
103_E	117_H	3.356	1.00
276_L	279_A	3.344	1.00
223_P	256_A	3.328	1.00
132_S	221_A	3.284	1.00
56_Y	109_F	3.208	1.00
272_E	275_Y	3.155	1.00
447_I	471_I	3.065	1.00
86_H	215_S	2.961	1.00
270_S	274_F	2.955	1.00
294_S	297_L	2.938	1.00
139_S	211_V	2.930	1.00
297_L	301_A	2.884	1.00
76_I	98_L	2.832	1.00
249_P	253_L	2.732	1.00
80_G	96_F	2.707	1.00
329_R	353_D	2.681	1.00
319_A	327_E	2.632	1.00
274_F	279_A	2.584	1.00
461_S	465_A	2.579	1.00
116_L	134_M	2.476	1.00
129_Q	228_K	2.438	1.00
241_E	251_S	2.363	1.00
312_Q	331_T	2.291	1.00
275_Y	279_A	2.282	1.00
72_L	275_Y	2.275	1.00
239_P	244_L	2.262	1.00
353_D	365_R	2.231	1.00
363_I	382_L	2.227	1.00
163_G	185_T	2.219	1.00
79_L	217_F	2.180	1.00
329_R	356_Q	2.169	1.00
135_A	212_L	2.160	1.00
272_E	279_A	2.152	1.00
315_R	319_A	2.084	1.00
190_R	193_M	2.035	1.00
271_S	274_F	1.995	1.00
124_S	272_E	1.975	1.00
24_P	27_A	1.974	1.00
354_L	385_A	1.953	1.00
126_N	129_Q	1.925	1.00
454_S	468_D	1.908	1.00
370_R	378_L	1.904	1.00
50_M	54_D	1.880	1.00
269_Q	272_E	1.845	0.99
167_S	182_L	1.802	0.99
101_N	117_H	1.794	0.99
272_E	277_A	1.793	0.99
97_F	115_V	1.791	0.99
438_A	477_L	1.786	0.99
38_T	41_G	1.785	0.99
196_F	200_N	1.777	0.99
223_P	260_A	1.775	0.99
319_A	331_T	1.774	0.99
392_P	419_A	1.770	0.99
425_N	428_Q	1.765	0.99
129_Q	224_T	1.756	0.99
277_A	280_R	1.755	0.99
369_A	378_L	1.726	0.99
339_E	345_Y	1.722	0.99
54_D	113_N	1.714	0.99
72_L	98_L	1.714	0.99
447_I	474_L	1.712	0.99
430_L	452_S	1.711	0.99
94_F	142_T	1.697	0.99
451_S	475_R	1.681	0.99
309_R	338_A	1.663	0.99
278_K	282_L	1.648	0.99
202_Q	251_S	1.645	0.99
431_A	466_R	1.631	0.99
319_A	324_K	1.627	0.99
139_S	142_T	1.626	0.99
39_S	151_E	1.618	0.98
274_F	283_G	1.616	0.98
67_I	118_S	1.597	0.98
104_I	123_Y	1.592	0.98
294_S	298_D	1.580	0.98
273_D	276_L	1.578	0.98
57_V	113_N	1.573	0.98
163_G	167_S	1.552	0.98
320_M	325_Y	1.551	0.98
128_S	221_A	1.543	0.98
276_L	283_G	1.541	0.98
76_I	96_F	1.512	0.98
274_F	277_A	1.504	0.98
179_M	183_T	1.502	0.98
131_A	212_L	1.499	0.98
159_L	163_G	1.483	0.97
167_S	181_A	1.483	0.97
329_R	333_Q	1.483	0.97
396_A	420_E	1.473	0.97
50_M	113_N	1.469	0.97
290_N	293_T	1.467	0.97
180_A	184_G	1.449	0.97
349_A	353_D	1.442	0.97
227_E	257_R	1.434	0.97
57_V	61_R	1.430	0.97
336_L	349_A	1.402	0.96
276_L	280_R	1.380	0.96
238_R	244_L	1.375	0.96
387_L	419_A	1.371	0.96
197_T	200_N	1.368	0.96
367_K	382_L	1.364	0.96
438_A	474_L	1.358	0.96
162_V	178_G	1.354	0.95
14_I	17_M	1.350	0.95
363_I	385_A	1.349	0.95
186_L	190_R	1.343	0.95
209_I	256_A	1.336	0.95
199_Q	202_Q	1.335	0.95
121_F	130_L	1.330	0.95
406_N	409_D	1.329	0.95
403_T	412_G	1.319	0.95
413_W	432_A	1.316	0.95
114_V	138_I	1.309	0.95
367_K	394_E	1.305	0.94
305_V	308_Q	1.293	0.94
272_E	281_T	1.291	0.94
79_L	130_L	1.288	0.94
98_L	121_F	1.286	0.94
442_R	445_Q	1.284	0.94
350_T	366_L	1.282	0.94
176_Q	179_M	1.277	0.94
83_L	138_I	1.270	0.94
37_G	148_R	1.266	0.93
396_A	416_L	1.264	0.93
156_S	159_L	1.258	0.93
148_R	203_E	1.255	0.93
49_E	144_R	1.254	0.93
430_L	449_L	1.253	0.93
19_I	24_P	1.245	0.93
76_I	116_L	1.244	0.93
444_D	478_Q	1.242	0.93
97_F	113_N	1.241	0.93
353_D	361_E	1.240	0.93
309_R	345_Y	1.238	0.93
202_Q	255_D	1.229	0.92
470_R	474_L	1.227	0.92
271_S	276_L	1.201	0.92
209_I	260_A	1.201	0.92
279_A	283_G	1.198	0.91
72_L	279_A	1.191	0.91
87_A	90_V	1.189	0.91
216_G	248_L	1.180	0.91
124_S	130_L	1.175	0.91
297_L	300_W	1.172	0.91
333_Q	337_A	1.167	0.90
450_L	467_Y	1.166	0.90
460_G	465_A	1.162	0.90
152_D	155_R	1.160	0.90
83_L	211_V	1.158	0.90
62_G	221_A	1.156	0.90
276_L	281_T	1.155	0.90
149_A	200_N	1.153	0.90
138_I	141_V	1.152	0.90
290_N	294_S	1.152	0.90
80_G	225_F	1.148	0.90
56_Y	60_L	1.148	0.90
209_I	213_Q	1.148	0.90
57_V	97_F	1.146	0.90
71_L	351_D	1.146	0.90
109_F	146_L	1.137	0.89
420_E	425_N	1.136	0.89
349_A	352_I	1.135	0.89
23_A	26_F	1.134	0.89
351_D	381_N	1.132	0.89
385_A	389_G	1.132	0.89
382_L	398_I	1.127	0.89
276_L	290_N	1.118	0.88
392_P	422_A	1.118	0.88
317_L	348_L	1.116	0.88
13_L	17_M	1.115	0.88
363_I	389_G	1.112	0.88
331_T	334_P	1.106	0.88
475_R	478_Q	1.104	0.88
403_T	416_L	1.104	0.88
339_E	342_N	1.098	0.87
275_Y	344_W	1.098	0.87
387_L	392_P	1.097	0.87
220_Q	261_N	1.097	0.87
56_Y	64_A	1.093	0.87
366_L	381_N	1.085	0.87
289_R	293_T	1.084	0.87
269_Q	275_Y	1.082	0.87
313_Y	317_L	1.076	0.86
213_Q	263_M	1.075	0.86
329_R	352_I	1.065	0.86
333_Q	349_A	1.064	0.86
12_T	15_A	1.063	0.86
386_Y	394_E	1.059	0.85
421_A	429_E	1.055	0.85
107_F	115_V	1.054	0.85
166_G	170_L	1.050	0.85
79_L	83_L	1.043	0.85
50_M	93_P	1.042	0.84
256_A	260_A	1.041	0.84
332_L	348_L	1.040	0.84
191_Q	197_T	1.033	0.84
272_E	283_G	1.033	0.84
384_N	415_L	1.031	0.84
348_L	352_I	1.025	0.84
191_Q	194_I	1.023	0.83
273_D	279_A	1.023	0.83
293_T	296_L	1.019	0.83
27_A	30_A	1.012	0.83
175_P	178_G	1.012	0.83
248_L	256_A	1.012	0.83
96_F	225_F	1.011	0.83
171_A	177_A	1.005	0.82
376_P	409_D	1.005	0.82
298_D	302_K	1.003	0.82
274_F	345_Y	1.003	0.82
318_Q	322_A	1.003	0.82
174_S	177_A	1.002	0.82
320_M	355_G	0.996	0.82
188_G	229_L	0.994	0.82
383_A	399_L	0.991	0.81
320_M	352_I	0.987	0.81
325_Y	352_I	0.979	0.81
167_S	171_A	0.977	0.80
72_L	277_A	0.973	0.80
213_Q	219_P	0.972	0.80
271_S	275_Y	0.969	0.80
276_L	285_Y	0.967	0.80
206_R	255_D	0.963	0.79
281_T	284_M	0.963	0.79
135_A	215_S	0.962	0.79
400_N	420_E	0.962	0.79
132_S	222_M	0.958	0.79
276_L	287_S	0.957	0.79
147_A	432_A	0.956	0.79
229_L	233_A	0.949	0.78
158_P	161_W	0.946	0.78
13_L	16_A	0.944	0.78
460_G	463_Q	0.940	0.78
453_A	467_Y	0.939	0.78
276_L	284_M	0.939	0.78
96_F	138_I	0.936	0.78
175_P	183_T	0.932	0.77
415_L	419_A	0.931	0.77
125_D	129_Q	0.929	0.77
150_M	153_Q	0.926	0.77
167_S	185_T	0.923	0.77
346_L	369_A	0.921	0.76
316_A	320_M	0.920	0.76
109_F	113_N	0.919	0.76
470_R	473_Q	0.918	0.76
177_A	181_A	0.917	0.76
238_R	250_E	0.916	0.76
274_F	280_R	0.913	0.76
314_G	318_Q	0.911	0.76
296_L	300_W	0.911	0.76
162_V	254_A	0.909	0.75
15_A	18_T	0.907	0.75
115_V	226_L	0.907	0.75
360_N	391_Q	0.907	0.75
224_T	229_L	0.906	0.75
447_I	478_Q	0.903	0.75
116_L	249_P	0.898	0.75
353_D	356_Q	0.895	0.74
169_L	194_I	0.893	0.74
384_N	388_Q	0.893	0.74
329_R	349_A	0.891	0.74
124_S	196_F	0.889	0.74
387_L	415_L	0.888	0.74
223_P	255_D	0.883	0.73
133_V	259_R	0.883	0.73
80_G	138_I	0.880	0.73
230_L	253_L	0.880	0.73
312_Q	334_P	0.873	0.72
289_R	294_S	0.872	0.72
403_T	413_W	0.860	0.71
39_S	163_G	0.856	0.71
478_Q	482_K	0.854	0.71
471_I	475_R	0.853	0.71
342_N	345_Y	0.850	0.70
48_Q	51_Q	0.848	0.70
297_L	314_G	0.848	0.70
320_M	348_L	0.847	0.70
230_L	249_P	0.846	0.70
52_M	55_Y	0.846	0.70
170_L	185_T	0.845	0.70
273_D	277_A	0.845	0.70
74_Q	207_I	0.842	0.70
398_I	402_Y	0.841	0.70
349_A	365_R	0.841	0.70
57_V	60_L	0.838	0.69
153_Q	157_A	0.836	0.69
478_Q	481_F	0.835	0.69
84_V	94_F	0.833	0.69
241_E	244_L	0.830	0.69
167_S	178_G	0.828	0.68
353_D	358_K	0.828	0.68
430_L	453_A	0.827	0.68
71_L	377_V	0.827	0.68
248_L	253_L	0.827	0.68
275_Y	281_T	0.827	0.68
272_E	285_Y	0.827	0.68
379_Q	398_I	0.825	0.68
99_I	207_I	0.821	0.68
58_R	62_G	0.819	0.68
379_Q	402_Y	0.815	0.67
359_A	385_A	0.814	0.67
434_A	441_G	0.812	0.67
287_S	291_Q	0.812	0.67
270_S	275_Y	0.812	0.67
185_T	382_L	0.810	0.67
291_Q	294_S	0.809	0.67
449_L	452_S	0.809	0.67
471_I	474_L	0.809	0.67
463_Q	466_R	0.808	0.66
308_Q	311_A	0.807	0.66
316_A	348_L	0.807	0.66
417_A	471_I	0.802	0.66
194_I	200_N	0.802	0.66
89_S	142_T	0.800	0.66
274_F	285_Y	0.799	0.66
363_I	386_Y	0.796	0.65
281_T	304_N	0.796	0.65
126_N	228_K	0.795	0.65
466_R	471_I	0.793	0.65
414_D	418_Q	0.791	0.65
80_G	94_F	0.791	0.65
465_A	472_D	0.791	0.65
287_S	290_N	0.787	0.64
334_P	337_A	0.786	0.64
139_S	200_N	0.783	0.64
88_N	214_R	0.781	0.64
74_Q	375_N	0.780	0.64
469_A	473_Q	0.780	0.64
53_G	113_N	0.777	0.63
186_L	189_T	0.776	0.63
263_M	357_N	0.776	0.63
450_L	454_S	0.775	0.63
237_S	244_L	0.774	0.63
304_N	308_Q	0.772	0.63
277_A	281_T	0.771	0.63
183_T	186_L	0.770	0.63
351_D	354_L	0.768	0.63
100_N	215_S	0.764	0.62
17_M	190_R	0.764	0.62
276_L	286_N	0.763	0.62
427_D	467_Y	0.762	0.62
245_T	390_G	0.760	0.62
14_I	26_F	0.757	0.61
160_T	189_T	0.754	0.61
71_L	278_K	0.754	0.61
135_A	222_M	0.750	0.61
75_Y	79_L	0.748	0.60
279_A	285_Y	0.748	0.60
312_Q	338_A	0.747	0.60
382_L	458_K	0.747	0.60
361_E	364_N	0.746	0.60
215_S	230_L	0.742	0.60
131_A	259_R	0.741	0.60
54_D	93_P	0.740	0.60
86_H	211_V	0.740	0.60
95_H	113_N	0.740	0.60
420_E	432_A	0.735	0.59
134_M	211_V	0.734	0.59
113_N	146_L	0.734	0.59
326_D	330_K	0.733	0.59
376_P	402_Y	0.733	0.59
270_S	276_L	0.732	0.59
352_I	356_Q	0.732	0.59
400_N	416_L	0.731	0.59
141_V	146_L	0.729	0.58
364_N	371_D	0.725	0.58
132_S	223_P	0.725	0.58
226_L	256_A	0.725	0.58
310_A	314_G	0.724	0.58
476_Q	480_R	0.723	0.58
368_N	371_D	0.723	0.58
79_L	134_M	0.721	0.58
75_Y	417_A	0.720	0.58
50_M	95_H	0.719	0.57
128_S	225_F	0.719	0.57
80_G	114_V	0.719	0.57
420_E	428_Q	0.714	0.57
67_I	98_L	0.713	0.57
146_L	196_F	0.710	0.56
376_P	406_N	0.710	0.56
97_F	109_F	0.710	0.56
90_V	188_G	0.709	0.56
275_Y	290_N	0.706	0.56
215_S	221_A	0.706	0.56
473_Q	477_L	0.705	0.56
94_F	212_L	0.704	0.56
209_I	263_M	0.703	0.56
347_D	381_N	0.702	0.56
89_S	375_N	0.701	0.56
185_T	189_T	0.701	0.56
300_W	303_G	0.700	0.55
160_T	188_G	0.698	0.55
111_G	144_R	0.697	0.55
298_D	301_A	0.695	0.55
165_L	168_I	0.693	0.55
73_T	76_I	0.693	0.55
184_G	188_G	0.691	0.54
312_Q	335_L	0.691	0.54
52_M	478_Q	0.690	0.54
291_Q	297_L	0.689	0.54
465_A	470_R	0.687	0.54
132_S	170_L	0.686	0.54
335_L	345_Y	0.685	0.54
209_I	242_I	0.685	0.54
359_A	363_I	0.685	0.54
279_A	286_N	0.685	0.54
74_Q	86_H	0.684	0.54
438_A	447_I	0.684	0.54
277_A	290_N	0.682	0.53
12_T	16_A	0.682	0.53
386_Y	391_Q	0.681	0.53
380_L	412_G	0.681	0.53
387_L	395_A	0.681	0.53
215_S	337_A	0.680	0.53
101_N	206_R	0.680	0.53
36_M	172_M	0.680	0.53
195_S	242_I	0.679	0.53
372_L	392_P	0.676	0.53
42_S	114_V	0.675	0.53
220_Q	260_A	0.675	0.53
211_V	256_A	0.674	0.53
431_A	467_Y	0.674	0.53
116_L	150_M	0.673	0.53
90_V	366_L	0.668	0.52
60_L	113_N	0.664	0.52
161_W	165_L	0.664	0.52
360_N	371_D	0.663	0.51
250_E	419_A	0.663	0.51
242_I	256_A	0.662	0.51
292_L	295_D	0.661	0.51
450_L	474_L	0.661	0.51
418_Q	422_A	0.660	0.51
325_Y	356_Q	0.659	0.51
269_Q	276_L	0.658	0.51
80_G	413_W	0.658	0.51
16_A	23_A	0.658	0.51
364_N	367_K	0.657	0.51
129_Q	244_L	0.657	0.51
139_S	256_A	0.655	0.51
367_K	391_Q	0.652	0.50
56_Y	146_L	0.651	0.50
377_V	417_A	0.651	0.50
240_P	244_L	0.651	0.50
99_I	109_F	0.651	0.50
279_A	290_N	0.650	0.50
197_T	202_Q	0.649	0.50
427_D	459_L	0.648	0.50
163_G	187_A	0.648	0.50
272_E	284_M	0.647	0.50
101_N	445_Q	0.646	0.50
315_R	461_S	0.645	0.49
156_S	219_P	0.645	0.49
57_V	109_F	0.645	0.49
413_W	416_L	0.645	0.49
80_G	97_F	0.644	0.49
197_T	413_W	0.643	0.49
71_L	153_Q	0.643	0.49
240_P	251_S	0.642	0.49
233_A	236_S	0.642	0.49
245_T	329_R	0.640	0.49
36_M	306_R	0.639	0.49
161_W	460_G	0.639	0.49
80_G	146_L	0.638	0.49
251_S	448_S	0.637	0.49
163_G	377_V	0.636	0.49
295_D	299_E	0.636	0.49
55_Y	164_A	0.636	0.49
386_Y	398_I	0.635	0.48
41_G	44_L	0.634	0.48
96_F	217_F	0.633	0.48
212_L	343_A	0.633	0.48
433_R	436_G	0.632	0.48
196_F	443_L	0.632	0.48
277_A	294_S	0.631	0.48
454_S	467_Y	0.631	0.48
402_Y	412_G	0.630	0.48
164_A	480_R	0.629	0.48
60_L	64_A	0.627	0.48
32_T	354_L	0.627	0.48
181_A	346_L	0.625	0.47
170_L	231_D	0.625	0.47
277_A	313_Y	0.623	0.47
120_L	243_L	0.623	0.47
417_A	433_R	0.623	0.47
118_S	281_T	0.622	0.47
80_G	141_V	0.622	0.47
350_T	365_R	0.621	0.47
94_F	138_I	0.621	0.47
207_I	210_Q	0.621	0.47
222_M	441_G	0.621	0.47
96_F	127_E	0.620	0.47
80_G	127_E	0.618	0.47
128_S	271_S	0.617	0.46
286_N	290_N	0.616	0.46
416_L	432_A	0.616	0.46
72_L	320_M	0.616	0.46
162_V	222_M	0.616	0.46
271_S	277_A	0.615	0.46
60_L	99_I	0.615	0.46
420_E	423_L	0.614	0.46
460_G	471_I	0.614	0.46
118_S	279_A	0.613	0.46
356_Q	386_Y	0.613	0.46
52_M	109_F	0.613	0.46
122_R	279_A	0.612	0.46
360_N	389_G	0.612	0.46
262_Q	367_K	0.612	0.46
59_Q	62_G	0.612	0.46
146_L	150_M	0.611	0.46
35_D	188_G	0.611	0.46
256_A	441_G	0.611	0.46
51_Q	480_R	0.610	0.46
117_H	142_T	0.608	0.46
234_R	243_L	0.608	0.46
335_L	340_P	0.608	0.46
118_S	332_L	0.607	0.45
170_L	206_R	0.606	0.45
176_Q	434_A	0.606	0.45
53_G	61_R	0.606	0.45
292_L	296_L	0.605	0.45
115_V	465_A	0.602	0.45
222_M	256_A	0.602	0.45
294_S	301_A	0.601	0.45
193_M	229_L	0.601	0.45
290_N	297_L	0.600	0.45
60_L	141_V	0.600	0.45
464_Q	468_D	0.600	0.45
200_N	259_R	0.598	0.44
58_R	435_E	0.597	0.44
116_L	395_A	0.597	0.44
160_T	229_L	0.594	0.44
191_Q	242_I	0.593	0.44
187_A	200_N	0.592	0.44
61_R	441_G	0.591	0.44
111_G	242_I	0.591	0.44
65_P	100_N	0.591	0.44
281_T	317_L	0.591	0.44
86_H	214_R	0.589	0.43
42_S	45_S	0.588	0.43
460_G	467_Y	0.588	0.43
164_A	182_L	0.587	0.43
44_L	138_I	0.587	0.43
138_I	225_F	0.586	0.43
35_D	398_I	0.585	0.43
414_D	436_G	0.583	0.43
413_W	438_A	0.583	0.43
394_E	464_Q	0.582	0.43
468_D	472_D	0.580	0.43
317_L	320_M	0.579	0.42
38_T	44_L	0.579	0.42
53_G	132_S	0.579	0.42
157_A	166_G	0.578	0.42
141_V	274_F	0.578	0.42
77_N	406_N	0.578	0.42
292_L	297_L	0.577	0.42
394_E	397_N	0.577	0.42
84_V	138_I	0.577	0.42
52_M	110_F	0.576	0.42
132_S	248_L	0.576	0.42
431_A	445_Q	0.574	0.42
147_A	248_L	0.573	0.42
244_L	250_E	0.572	0.42
99_I	162_V	0.571	0.42
69_D	278_K	0.570	0.41
89_S	94_F	0.570	0.41
121_F	382_L	0.569	0.41
344_W	347_D	0.567	0.41
332_L	349_A	0.567	0.41
280_R	283_G	0.567	0.41
227_E	231_D	0.565	0.41
80_G	130_L	0.565	0.41
196_F	248_L	0.565	0.41
418_Q	437_Y	0.564	0.41
124_S	153_Q	0.564	0.41
274_F	289_R	0.563	0.41
16_A	24_P	0.563	0.41
118_S	130_L	0.561	0.41
109_F	217_F	0.561	0.41
104_I	222_M	0.561	0.41
242_I	432_A	0.560	0.40
77_N	408_D	0.559	0.40
290_N	296_L	0.558	0.40
107_F	110_F	0.558	0.40
192_G	413_W	0.558	0.40
14_I	371_D	0.557	0.40
110_F	429_E	0.556	0.40
96_F	141_V	0.556	0.40
40_A	144_R	0.555	0.40
194_I	256_A	0.555	0.40
342_N	347_D	0.555	0.40
43_T	182_L	0.554	0.40
99_I	115_V	0.554	0.40
56_Y	187_A	0.554	0.40
165_L	406_N	0.553	0.40
130_L	225_F	0.553	0.40
419_A	424_N	0.553	0.40
183_T	188_G	0.553	0.40
466_R	470_R	0.553	0.40
59_Q	466_R	0.551	0.39
276_L	314_G	0.551	0.39
403_T	469_A	0.551	0.39
350_T	386_Y	0.551	0.39
123_Y	232_Q	0.550	0.39
85_S	138_I	0.550	0.39
300_W	305_V	0.549	0.39
176_Q	211_V	0.548	0.39
114_V	192_G	0.548	0.39
280_R	284_M	0.547	0.39
253_L	383_A	0.547	0.39
366_L	433_R	0.546	0.39
40_A	115_V	0.545	0.39
279_A	284_M	0.544	0.39
24_P	337_A	0.544	0.39
436_G	440_A	0.543	0.39
60_L	173_A	0.543	0.39
431_A	435_E	0.543	0.39
221_A	248_L	0.542	0.39
396_A	419_A	0.542	0.39
467_Y	474_L	0.542	0.39
85_S	314_G	0.540	0.38
396_A	423_L	0.540	0.38
12_T	22_V	0.540	0.38
117_H	224_T	0.539	0.38
41_G	144_R	0.538	0.38
160_T	185_T	0.538	0.38
24_P	182_L	0.537	0.38
293_T	301_A	0.537	0.38
87_A	234_R	0.535	0.38
409_D	413_W	0.535	0.38
354_L	359_A	0.534	0.38
56_Y	257_R	0.531	0.37
357_N	385_A	0.531	0.37
231_D	234_R	0.530	0.37
139_S	207_I	0.530	0.37
414_D	437_Y	0.529	0.37
426_R	429_E	0.529	0.37
272_E	280_R	0.528	0.37
124_S	226_L	0.528	0.37
80_G	131_A	0.527	0.37
225_F	396_A	0.526	0.37
293_T	298_D	0.525	0.37
32_T	473_Q	0.525	0.37
43_T	150_M	0.523	0.37
448_S	452_S	0.522	0.37
218_D	224_T	0.522	0.37
310_A	469_A	0.522	0.37
158_P	450_L	0.522	0.37
443_L	478_Q	0.521	0.36
167_S	196_F	0.520	0.36
160_T	420_E	0.520	0.36
80_G	134_M	0.519	0.36
283_G	286_N	0.518	0.36
279_A	282_L	0.518	0.36
329_R	371_D	0.518	0.36
418_Q	443_L	0.516	0.36
143_Q	259_R	0.515	0.36
44_L	254_A	0.514	0.36
124_S	212_L	0.514	0.36
414_D	433_R	0.514	0.36
63_S	66_L	0.514	0.36
49_E	147_A	0.514	0.36
369_A	373_R	0.513	0.36
331_T	335_L	0.512	0.36
211_V	471_I	0.512	0.36
76_I	79_L	0.511	0.35
330_K	333_Q	0.511	0.35
115_V	196_F	0.511	0.35
211_V	215_S	0.510	0.35
71_L	128_S	0.509	0.35
149_A	195_S	0.509	0.35
110_F	166_G	0.508	0.35
72_L	478_Q	0.507	0.35
332_L	434_A	0.507	0.35
210_Q	254_A	0.507	0.35
395_A	418_Q	0.507	0.35
128_S	217_F	0.506	0.35
343_A	347_D	0.506	0.35
224_T	228_K	0.506	0.35
200_N	277_A	0.505	0.35
158_P	162_V	0.505	0.35
65_P	79_L	0.505	0.35
384_N	418_Q	0.504	0.35
48_Q	452_S	0.503	0.35
187_A	431_A	0.502	0.35
132_S	320_M	0.502	0.35
142_T	175_P	0.502	0.35
187_A	229_L	0.502	0.35
271_S	290_N	0.501	0.34
142_T	146_L	0.501	0.34
82_R	217_F	0.501	0.34
361_E	367_K	0.500	0.34
277_A	293_T	0.500	0.34

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3c37_A	1	0.4559	100	0.714	Contact Map
4aw6_A	1	0.4949	100	0.828	Contact Map
4il3_A	1	0.4805	100	0.828	Contact Map
3as5_A	1	0.3388	99.6	0.894	Contact Map
1xnf_A	1	0.4148	99.6	0.897	Contact Map
3ieg_A	1	0.4415	99.6	0.897	Contact Map
2yhc_A	1	0.3696	99.6	0.898	Contact Map
2pl2_A	1	0.3347	99.5	0.898	Contact Map
3jb9_R	1	0.0246	99.5	0.899	Contact Map
3vtx_A	1	0.3347	99.5	0.9	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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