GREMLIN Database
COMP - Sensor histidine kinase ComP
UniProt: Q99027 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 769 (606)
Sequences: 1011 (943)
Seq/√Len: 38.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
535_H539_L4.2481.00
696_S719_D4.2091.00
539_L542_H3.9521.00
684_I743_R3.8201.00
696_S699_T3.5021.00
532_N535_H3.3121.00
186_S190_Y3.2641.00
756_S759_K3.2451.00
257_L261_K3.1761.00
630_C633_L3.0731.00
574_D582_D3.0391.00
741_K745_R2.8071.00
183_F190_Y2.7751.00
536_I539_L2.7161.00
717_E762_K2.6841.00
699_T719_D2.6561.00
684_I744_V2.6121.00
535_H542_H2.5801.00
650_L689_L2.5621.00
740_I743_R2.5491.00
685_I714_L2.5461.00
740_I751_L2.5421.00
744_V765_I2.5421.00
744_V749_G2.5141.00
743_R747_L2.4641.00
647_L685_I2.4491.00
627_R633_L2.4221.00
580_L584_I2.3991.00
515_E518_W2.3831.00
535_H538_E2.3671.00
183_F186_S2.3231.00
718_D722_G2.2901.00
538_E542_H2.2871.00
564_E567_Q2.2721.00
256_Y260_N2.2661.00
572_A581_Q2.2580.99
660_F664_L2.2530.99
574_D683_R2.2150.99
567_Q695_H2.2020.99
581_Q694_K2.1930.99
642_G645_K2.1720.99
704_M715_H2.1580.99
627_R630_C2.1470.99
687_E695_H2.1200.99
252_F256_Y2.0930.99
711_K766_E2.0690.99
573_R732_S2.0510.99
568_R695_H2.0470.99
384_K388_D2.0440.99
573_R687_E2.0420.99
430_I434_L2.0300.99
619_M683_R2.0300.99
566_K569_S2.0230.99
683_R686_Q2.0230.99
249_L252_F2.0070.99
307_A311_V2.0070.99
581_Q588_R2.0040.99
573_R734_S1.9880.99
125_F129_S1.9770.99
581_Q695_H1.9360.98
567_Q570_G1.9320.98
538_E541_E1.9310.98
179_N182_T1.9270.98
403_Q413_M1.9220.98
564_E572_A1.9120.98
324_N328_D1.8950.98
560_M621_D1.8910.98
570_G574_D1.8790.98
377_M380_V1.8670.98
581_Q584_I1.8620.98
530_M533_V1.8410.98
749_G767_I1.8270.98
523_S528_V1.8250.98
558_K562_A1.8170.98
565_E568_R1.8160.98
530_M539_L1.8140.98
683_R747_L1.8130.98
306_S311_V1.7980.97
564_E568_R1.7790.97
639_Y678_Q1.7770.97
724_D757_E1.7680.97
523_S527_S1.7660.97
304_L311_V1.7580.97
688_F740_I1.7530.97
755_T761_F1.7520.97
588_R683_R1.7480.97
687_E732_S1.7470.97
478_K482_V1.7470.97
532_N539_L1.7460.97
557_K560_M1.7320.97
575_L625_M1.7300.97
572_A694_K1.7270.97
567_Q572_A1.7260.97
580_L588_R1.7210.97
130_I133_I1.7210.97
427_K439_A1.7010.96
568_R581_Q1.6980.96
643_L712_I1.6980.96
372_F380_V1.6910.96
374_F380_V1.6890.96
533_V539_L1.6770.96
564_E581_Q1.6720.96
130_I134_F1.6700.96
303_A306_S1.6680.96
564_E695_H1.6650.96
257_L260_N1.6590.96
684_I740_I1.6540.96
445_T449_K1.6530.96
723_F737_L1.6450.96
692_A701_V1.6400.95
182_T186_S1.6390.95
567_Q581_Q1.6360.95
304_L307_A1.5940.95
254_A258_H1.5920.95
209_I213_Y1.5880.95
715_H764_D1.5800.94
252_F258_H1.5720.94
252_F257_L1.5700.94
248_T256_Y1.5620.94
580_L694_K1.5540.94
521_T528_V1.5440.94
689_L701_V1.5430.94
565_E570_G1.5400.94
372_F376_V1.5370.94
572_A695_H1.5340.94
186_S197_Y1.5210.93
718_D760_G1.5200.93
663_R700_D1.5020.93
334_G341_L1.4970.93
753_I761_F1.4880.92
182_T190_Y1.4840.92
567_Q687_E1.4830.92
452_F455_K1.4790.92
532_N538_E1.4780.92
335_R343_A1.4760.92
179_N190_Y1.4730.92
323_A327_F1.4660.92
735_M739_G1.4560.92
249_L253_S1.4550.92
586_L683_R1.4540.92
477_G480_I1.4390.91
485_G489_K1.4370.91
487_L501_L1.4280.91
688_F765_I1.4260.91
465_Y475_E1.4220.91
574_D618_Q1.4200.91
372_F384_K1.4180.90
565_E581_Q1.4150.90
567_Q683_R1.4110.90
306_S313_I1.4070.90
574_D686_Q1.4070.90
140_N143_R1.3980.90
581_Q585_S1.3980.90
380_V384_K1.3960.90
214_I218_F1.3920.90
427_K430_I1.3910.90
129_S133_I1.3880.90
728_N753_I1.3870.89
753_I763_A1.3780.89
348_L351_V1.3720.89
564_E694_K1.3700.89
567_Q573_R1.3660.89
568_R694_K1.3580.88
625_M632_E1.3580.88
582_D739_G1.3550.88
568_R572_A1.3550.88
687_E739_G1.3550.88
529_S535_H1.3440.88
606_E609_Q1.3430.88
580_L585_S1.3320.87
755_T759_K1.3230.87
754_E762_K1.3220.87
567_Q694_K1.3220.87
724_D727_K1.3210.87
683_R743_R1.3190.87
582_D687_E1.3190.87
534_L538_E1.3170.87
570_G626_T1.3160.87
307_A310_L1.3150.87
752_R764_D1.3110.87
324_N327_F1.3090.87
252_F260_N1.3070.86
580_L591_E1.3070.86
682_Y686_Q1.3040.86
361_D365_N1.2980.86
582_D723_F1.2940.86
643_L714_L1.2920.86
567_Q571_L1.2910.86
564_E570_G1.2890.86
680_N743_R1.2670.85
573_R677_S1.2650.85
567_Q580_L1.2470.84
695_H733_M1.2410.83
248_T258_H1.2380.83
569_S584_I1.2320.83
676_D747_L1.2270.83
127_F133_I1.2260.83
687_E740_I1.2190.82
680_N695_H1.2170.82
325_K328_D1.2150.82
703_I744_V1.2140.82
533_V536_I1.2110.82
321_F324_N1.2110.82
622_V694_K1.2080.82
568_R743_R1.2070.82
303_A307_A1.2060.82
564_E580_L1.1980.81
580_L587_K1.1970.81
427_K440_Y1.1910.81
426_L433_V1.1890.81
334_G343_A1.1860.81
193_F198_L1.1790.80
377_M388_D1.1790.80
532_N536_I1.1780.80
570_G695_H1.1720.80
256_Y261_K1.1720.80
258_H261_K1.1710.80
303_A311_V1.1710.80
703_I716_Y1.1710.80
427_K431_L1.1630.79
248_T252_F1.1600.79
183_F193_F1.1580.79
183_F187_P1.1550.79
348_L355_V1.1510.78
529_S538_E1.1450.78
507_N515_E1.1450.78
187_P190_Y1.1440.78
618_Q625_M1.1390.78
369_Q375_V1.1380.78
324_N332_I1.1320.77
665_N704_M1.1310.77
380_V389_F1.1290.77
574_D581_Q1.1240.77
150_I261_K1.1240.77
521_T527_S1.1230.77
618_Q626_T1.1230.77
565_E683_R1.1230.77
581_Q623_I1.1220.77
571_L695_H1.1210.77
687_E763_A1.1200.77
674_D681_L1.1200.77
755_T758_G1.1160.76
246_T260_N1.1160.76
687_E743_R1.1150.76
168_P171_G1.1140.76
427_K433_V1.1140.76
478_K481_E1.1130.76
623_I627_R1.1120.76
565_E580_L1.1100.76
573_R763_A1.1080.76
304_L308_S1.1030.75
401_N410_T1.1020.75
452_F457_E1.0990.75
713_V766_E1.0990.75
677_S732_S1.0970.75
570_G694_K1.0960.75
751_L763_A1.0940.75
589_Q592_L1.0920.75
322_V327_F1.0920.75
681_L685_I1.0910.75
179_N186_S1.0880.74
121_L133_I1.0770.74
186_S198_L1.0740.73
532_N542_H1.0730.73
154_L162_Y1.0680.73
591_E594_L1.0660.73
179_N183_F1.0650.73
126_Y130_I1.0640.73
566_K570_G1.0620.73
190_Y198_L1.0590.72
565_E571_L1.0580.72
252_F255_I1.0540.72
681_L765_I1.0540.72
573_R695_H1.0530.72
427_K436_V1.0510.72
621_D629_T1.0500.72
749_G768_E1.0480.72
586_L592_L1.0470.72
574_D588_R1.0450.71
453_L456_H1.0440.71
321_F325_K1.0430.71
568_R687_E1.0430.71
402_Y405_S1.0430.71
574_D739_G1.0350.71
574_D622_V1.0340.71
722_G760_G1.0330.70
380_V383_F1.0320.70
587_K619_M1.0300.70
680_N683_R1.0270.70
580_L586_L1.0240.70
476_I490_V1.0220.70
368_R381_F1.0200.69
567_Q743_R1.0190.69
588_R619_M1.0180.69
692_A696_S1.0180.69
179_N193_F1.0180.69
683_R739_G1.0180.69
581_Q589_Q1.0150.69
565_E695_H1.0140.69
574_D586_L1.0100.69
368_R372_F1.0080.69
483_N486_F1.0060.68
687_E737_L1.0040.68
525_Y528_V1.0000.68
627_R632_E1.0000.68
527_S531_E0.9990.68
512_T515_E0.9970.68
308_S311_V0.9950.68
588_R592_L0.9940.67
334_G344_M0.9930.67
427_K434_L0.9890.67
192_Q292_P0.9890.67
328_D332_I0.9890.67
695_H739_G0.9860.67
426_L436_V0.9850.67
580_L739_G0.9850.67
650_L686_Q0.9830.67
614_Q622_V0.9810.66
581_Q586_L0.9810.66
340_A344_M0.9790.66
584_I588_R0.9780.66
580_L695_H0.9780.66
683_R761_F0.9760.66
248_T255_I0.9750.66
333_L341_L0.9730.66
635_P646_A0.9730.66
163_I286_L0.9690.65
480_I489_K0.9680.65
695_H743_R0.9680.65
484_Q488_M0.9660.65
219_N716_Y0.9660.65
426_L434_L0.9650.65
690_S694_K0.9630.65
583_L592_L0.9620.65
584_I591_E0.9590.65
571_L719_D0.9570.65
564_E585_S0.9570.65
403_Q406_I0.9560.64
188_I224_F0.9550.64
569_S696_S0.9540.64
575_L653_Q0.9540.64
622_V625_M0.9520.64
444_V447_D0.9520.64
581_Q592_L0.9520.64
488_M491_G0.9480.64
674_D677_S0.9460.64
182_T189_L0.9450.64
645_K678_Q0.9440.63
125_F128_L0.9440.63
322_V325_K0.9430.63
142_K145_S0.9390.63
414_R427_K0.9380.63
688_F694_K0.9360.63
160_I214_I0.9350.63
190_Y193_F0.9330.63
636_Q684_I0.9320.62
623_I633_L0.9310.62
340_A343_A0.9300.62
596_D599_K0.9290.62
384_K389_F0.9290.62
663_R702_L0.9270.62
630_C695_H0.9260.62
371_V382_Y0.9240.62
402_Y407_F0.9240.62
400_F515_E0.9220.62
530_M542_H0.9210.61
341_L344_M0.9210.61
210_S218_F0.9200.61
222_I265_A0.9190.61
570_G622_V0.9190.61
483_N487_L0.9190.61
131_I136_I0.9190.61
647_L664_L0.9170.61
642_G646_A0.9150.61
398_E409_Y0.9140.61
646_A682_Y0.9100.61
583_L589_Q0.9080.60
689_L703_I0.9070.60
335_R339_Y0.9060.60
308_S315_F0.9050.60
131_I149_Y0.9040.60
431_L439_A0.9040.60
575_L733_M0.9010.60
583_L587_K0.9010.60
570_G580_L0.8980.60
568_R573_R0.8980.60
581_Q619_M0.8970.59
129_S134_F0.8960.59
186_S193_F0.8940.59
308_S312_L0.8940.59
421_Q427_K0.8940.59
570_G733_M0.8930.59
212_L242_V0.8930.59
640_D673_L0.8930.59
336_M343_A0.8920.59
176_R180_L0.8920.59
208_R757_E0.8910.59
657_R660_F0.8910.59
568_R582_D0.8880.59
571_L743_R0.8870.59
502_C505_N0.8870.59
706_I715_H0.8850.58
691_N718_D0.8840.58
360_M363_Q0.8830.58
570_G581_Q0.8830.58
565_E572_A0.8810.58
315_F321_F0.8810.58
580_L589_Q0.8790.58
696_S701_V0.8750.58
393_L402_Y0.8730.57
498_Y502_C0.8700.57
677_S687_E0.8690.57
476_I479_I0.8660.57
644_V705_L0.8640.57
567_Q696_S0.8630.56
676_D681_L0.8620.56
485_G488_M0.8620.56
689_L692_A0.8600.56
400_F403_Q0.8590.56
329_I335_R0.8580.56
687_E723_F0.8570.56
312_L315_F0.8560.56
423_F430_I0.8560.56
723_F734_S0.8560.56
563_I566_K0.8560.56
583_L630_C0.8540.56
355_V359_V0.8530.56
477_G482_V0.8530.56
327_F332_I0.8530.56
586_L589_Q0.8520.55
345_I348_L0.8520.55
256_Y259_L0.8520.55
361_D364_M0.8520.55
381_F385_E0.8500.55
406_I413_M0.8490.55
523_S526_T0.8480.55
405_S408_K0.8470.55
590_C615_M0.8460.55
567_Q625_M0.8460.55
182_T185_S0.8450.55
425_E429_T0.8440.55
732_S763_A0.8430.55
253_S257_L0.8410.55
533_V540_M0.8400.54
255_I271_L0.8400.54
424_K427_K0.8390.54
626_T747_L0.8390.54
734_S768_E0.8370.54
724_D753_I0.8370.54
702_L717_E0.8330.54
427_K437_S0.8320.54
321_F327_F0.8300.54
211_F217_I0.8300.54
567_Q584_I0.8300.54
581_Q587_K0.8290.53
150_I157_D0.8270.53
478_K483_N0.8270.53
158_I161_A0.8260.53
660_F666_T0.8250.53
618_Q683_R0.8240.53
302_P307_A0.8230.53
404_D408_K0.8220.53
627_R635_P0.8190.53
720_G736_G0.8180.52
144_R149_Y0.8170.52
572_A625_M0.8170.52
440_Y453_L0.8150.52
528_V533_V0.8150.52
674_D763_A0.8140.52
188_I192_Q0.8110.52
565_E569_S0.8110.52
509_P515_E0.8100.52
573_R735_M0.8090.52
523_S529_S0.8080.52
530_M535_H0.8080.52
484_Q489_K0.8060.51
585_S588_R0.8040.51
426_L430_I0.8040.51
591_E694_K0.8040.51
517_S520_K0.8040.51
249_L258_H0.8020.51
564_E588_R0.8020.51
635_P638_L0.8010.51
325_K332_I0.8000.51
329_I332_I0.7990.51
685_I701_V0.7980.51
677_S680_N0.7950.50
635_P682_Y0.7950.50
580_L630_C0.7930.50
567_Q732_S0.7910.50
560_M626_T0.7890.50
694_K743_R0.7880.50
687_E734_S0.7880.50
251_S254_A0.7840.49
557_K563_I0.7840.49
565_E747_L0.7820.49
565_E630_C0.7810.49
564_E626_T0.7800.49
572_A632_E0.7790.49
587_K629_T0.7780.49
557_K564_E0.7780.49
398_E406_I0.7770.49
680_N740_I0.7770.49
568_R733_M0.7770.49
571_L690_S0.7770.49
324_N341_L0.7750.49
276_L349_L0.7750.49
584_I623_I0.7730.48
336_M341_L0.7720.48
380_V385_E0.7720.48
405_S409_Y0.7710.48
268_S350_I0.7710.48
723_F735_M0.7700.48
402_Y406_I0.7690.48
688_F763_A0.7690.48
687_E733_M0.7680.48
372_F381_F0.7650.48
570_G687_E0.7640.48
371_V381_F0.7630.48
535_H540_M0.7620.47
688_F743_R0.7600.47
327_F341_L0.7600.47
607_E610_D0.7600.47
692_A732_S0.7580.47
372_F377_M0.7550.47
572_A591_E0.7550.47
127_F135_Y0.7530.47
310_L314_P0.7510.46
528_V535_H0.7500.46
498_Y527_S0.7490.46
573_R582_D0.7490.46
582_D737_L0.7460.46
377_M381_F0.7450.46
371_V380_V0.7430.46
331_F335_R0.7430.46
283_A287_I0.7430.46
484_Q487_L0.7420.46
621_D624_S0.7420.46
529_S533_V0.7420.46
183_F189_L0.7420.46
568_R625_M0.7410.46
206_L209_I0.7410.46
580_L763_A0.7410.46
641_L676_D0.7410.46
615_M621_D0.7400.45
569_S695_H0.7370.45
568_R696_S0.7350.45
570_G743_R0.7350.45
381_F384_K0.7350.45
345_I356_L0.7350.45
211_F218_F0.7340.45
586_L694_K0.7330.45
587_K694_K0.7310.45
659_P665_N0.7310.45
431_L435_L0.7290.44
573_R688_F0.7290.44
368_R380_V0.7280.44
144_R150_I0.7270.44
575_L694_K0.7240.44
515_E525_Y0.7220.44
742_E745_R0.7220.44
336_M340_A0.7220.44
678_Q688_F0.7210.44
557_K565_E0.7210.44
530_M538_E0.7200.44
248_T260_N0.7200.44
426_L445_T0.7190.44
426_L440_Y0.7170.43
422_V427_K0.7170.43
581_Q683_R0.7160.43
148_A151_L0.7150.43
575_L622_V0.7150.43
244_F252_F0.7150.43
573_R723_F0.7140.43
376_V384_K0.7130.43
251_S255_I0.7130.43
692_A755_T0.7120.43
486_F489_K0.7110.43
304_L310_L0.7080.43
409_Y767_I0.7060.42
736_G749_G0.7060.42
571_L696_S0.7050.42
633_L683_R0.7050.42
327_F330_E0.7040.42
632_E683_R0.7020.42
569_S732_S0.7020.42
501_L505_N0.7020.42
426_L438_K0.7010.42
507_N511_L0.7010.42
332_I343_A0.7000.42
611_K622_V0.7000.42
360_M365_N0.6990.42
184_I192_Q0.6970.42
564_E589_Q0.6960.42
335_R350_I0.6940.41
625_M630_C0.6930.41
286_L312_L0.6930.41
477_G481_E0.6920.41
680_N739_G0.6910.41
301_F307_A0.6910.41
335_R341_L0.6900.41
489_K493_R0.6890.41
384_K387_M0.6880.41
345_I357_F0.6880.41
448_H452_F0.6860.41
677_S763_A0.6860.41
408_K411_Q0.6840.41
567_Q761_F0.6830.40
570_G738_S0.6830.40
282_F575_L0.6820.40
505_N515_E0.6820.40
708_I711_K0.6800.40
325_K335_R0.6800.40
479_I487_L0.6790.40
635_P642_G0.6790.40
691_N736_G0.6780.40
557_K567_Q0.6760.40
402_Y410_T0.6760.40
634_R742_E0.6750.40
653_Q695_H0.6750.40
584_I587_K0.6750.40
402_Y409_Y0.6730.40
452_F456_H0.6710.39
211_F256_Y0.6700.39
241_L245_A0.6690.39
542_H557_K0.6690.39
192_Q213_Y0.6680.39
511_L539_L0.6680.39
185_S377_M0.6680.39
438_K503_L0.6670.39
567_Q630_C0.6670.39
131_I139_V0.6670.39
746_A763_A0.6650.39
321_F328_D0.6650.39
569_S586_L0.6640.39
690_S695_H0.6630.39
362_I365_N0.6630.39
750_R766_E0.6620.39
445_T448_H0.6620.39
521_T529_S0.6610.39
646_A685_I0.6600.38
246_T251_S0.6600.38
133_I139_V0.6590.38
691_N720_G0.6580.38
622_V627_R0.6580.38
728_N731_H0.6560.38
219_N422_V0.6550.38
661_H700_D0.6540.38
239_L243_S0.6530.38
505_N511_L0.6530.38
708_I713_V0.6520.38
529_S532_N0.6520.38
732_S761_F0.6490.38
534_L537_E0.6480.37
643_L750_R0.6480.37
306_S315_F0.6470.37
165_A280_L0.6460.37
222_I765_I0.6460.37
533_V542_H0.6460.37
396_F400_F0.6450.37
185_S209_I0.6440.37
498_Y505_N0.6430.37
586_L622_V0.6430.37
127_F130_I0.6420.37
324_N343_A0.6420.37
328_D335_R0.6410.37
206_L278_N0.6410.37
629_T633_L0.6410.37
683_R695_H0.6400.37
453_L457_E0.6390.37
393_L398_E0.6390.37
451_I454_D0.6380.37
311_V315_F0.6370.37
528_V532_N0.6350.36
521_T525_Y0.6350.36
569_S699_T0.6350.36
127_F139_V0.6330.36
582_D588_R0.6330.36
401_N405_S0.6330.36
178_I643_L0.6320.36
186_S189_L0.6320.36
386_V390_K0.6310.36
612_L633_L0.6300.36
700_D719_D0.6300.36
745_R750_R0.6300.36
515_E526_T0.6290.36
521_T524_F0.6290.36
570_G634_R0.6280.36
423_F441_T0.6270.36
137_L262_Y0.6270.36
367_V371_V0.6270.36
695_H746_A0.6260.36
574_D723_F0.6260.36
249_L349_L0.6260.36
428_N432_D0.6250.36
715_H762_K0.6240.35
582_D586_L0.6240.35
581_Q680_N0.6230.35
420_Q427_K0.6220.35
523_S530_M0.6220.35
687_E738_S0.6220.35
500_L503_L0.6220.35
154_L158_I0.6210.35
573_R580_L0.6210.35
350_I384_K0.6200.35
249_L256_Y0.6200.35
249_L257_L0.6190.35
181_F426_L0.6190.35
650_L682_Y0.6180.35
238_T241_L0.6180.35
588_R614_Q0.6170.35
645_K648_S0.6170.35
619_M623_I0.6160.35
210_S219_N0.6150.35
396_F402_Y0.6150.35
644_V648_S0.6150.35
323_A328_D0.6150.35
243_S248_T0.6140.35
184_I194_I0.6130.35
484_Q491_G0.6130.35
167_G170_R0.6110.34
640_D675_L0.6110.34
528_V536_I0.6100.34
348_L357_F0.6090.34
685_I729_T0.6090.34
332_I336_M0.6090.34
709_Q716_Y0.6080.34
323_A343_A0.6070.34
582_D763_A0.6060.34
156_L159_S0.6060.34
752_R766_E0.6060.34
429_T433_V0.6050.34
327_F335_R0.6040.34
582_D732_S0.6040.34
525_Y530_M0.6040.34
433_V440_Y0.6040.34
676_D695_H0.6030.34
573_R581_Q0.6020.34
283_A430_I0.6010.34
563_I629_T0.6010.34
344_M355_V0.6010.34
399_K402_Y0.6010.34
180_L184_I0.6000.34
582_D695_H0.5990.33
570_G741_K0.5980.33
450_V455_K0.5980.33
429_T529_S0.5970.33
413_M426_L0.5960.33
128_L136_I0.5960.33
402_Y413_M0.5960.33
324_N334_G0.5940.33
688_F722_G0.5940.33
567_Q763_A0.5930.33
570_G633_L0.5910.33
705_L712_I0.5910.33
628_E742_E0.5910.33
339_Y343_A0.5910.33
239_L712_I0.5890.33
572_A623_I0.5890.33
174_I367_V0.5880.33
643_L674_D0.5870.32
253_S368_R0.5860.32
149_Y748_D0.5850.32
514_D525_Y0.5840.32
167_G172_H0.5830.32
126_Y137_L0.5820.32
475_E481_E0.5810.32
559_L562_A0.5810.32
589_Q694_K0.5800.32
368_R376_V0.5800.32
584_I696_S0.5800.32
682_Y739_G0.5790.32
625_M633_L0.5780.32
718_D736_G0.5780.32
427_K519_L0.5770.32
566_K587_K0.5760.32
399_K406_I0.5760.32
147_A432_D0.5760.32
305_A319_Y0.5750.32
694_K739_G0.5730.31
516_I519_L0.5730.31
618_Q753_I0.5730.31
674_D687_E0.5720.31
179_N189_L0.5720.31
426_L441_T0.5710.31
369_Q376_V0.5710.31
413_M433_V0.5710.31
519_L525_Y0.5710.31
567_Q589_Q0.5710.31
312_L317_L0.5710.31
125_F135_Y0.5700.31
563_I622_V0.5700.31
573_R674_D0.5700.31
403_Q412_L0.5690.31
395_R400_F0.5670.31
522_L528_V0.5660.31
695_H732_S0.5650.31
399_K410_T0.5650.31
269_F373_F0.5640.31
301_F308_S0.5640.31
408_K425_E0.5620.31
497_S716_Y0.5620.31
328_D341_L0.5610.30
306_S328_D0.5610.30
157_D161_A0.5590.30
632_E653_Q0.5580.30
149_Y153_L0.5570.30
568_R626_T0.5560.30
303_A325_K0.5550.30
589_Q625_M0.5550.30
657_R661_H0.5550.30
237_A241_L0.5550.30
739_G763_A0.5540.30
568_R584_I0.5540.30
169_F173_I0.5530.30
570_G582_D0.5530.30
524_F528_V0.5530.30
301_F311_V0.5520.30
285_F288_F0.5520.30
134_F372_F0.5520.30
676_D749_G0.5510.30
437_S444_V0.5500.30
572_A583_L0.5500.30
242_V744_V0.5500.30
245_A260_N0.5490.30
572_A580_L0.5490.30
245_A276_L0.5490.30
564_E584_I0.5490.30
327_F343_A0.5470.29
314_P328_D0.5460.29
141_K144_R0.5460.29
695_H740_I0.5460.29
425_E444_V0.5450.29
573_R740_I0.5440.29
301_F306_S0.5430.29
494_G501_L0.5420.29
192_Q714_L0.5420.29
381_F388_D0.5420.29
319_Y424_K0.5410.29
250_F757_E0.5410.29
374_F379_A0.5410.29
694_K740_I0.5410.29
145_S148_A0.5400.29
332_I335_R0.5380.29
572_A582_D0.5380.29
332_I341_L0.5370.29
352_G355_V0.5370.29
606_E610_D0.5370.29
565_E633_L0.5360.29
571_L667_G0.5350.29
594_L607_E0.5350.29
413_M440_Y0.5350.29
119_F206_L0.5350.29
570_G583_L0.5350.29
181_F188_I0.5340.28
345_I710_N0.5320.28
613_V765_I0.5320.28
306_S309_L0.5300.28
328_D334_G0.5300.28
408_K412_L0.5300.28
373_F376_V0.5290.28
580_L687_E0.5290.28
525_Y529_S0.5290.28
281_S645_K0.5280.28
584_I633_L0.5280.28
390_K393_L0.5280.28
487_L490_V0.5270.28
185_S212_L0.5260.28
122_P135_Y0.5250.28
217_I345_I0.5250.28
633_L646_A0.5250.28
573_R593_F0.5250.28
565_E694_K0.5240.28
205_F716_Y0.5240.28
564_E746_A0.5220.28
575_L629_T0.5210.28
632_E733_M0.5210.28
720_G749_G0.5200.27
448_H453_L0.5200.27
581_Q739_G0.5180.27
437_S440_Y0.5180.27
565_E742_E0.5180.27
177_Y180_L0.5180.27
142_K225_F0.5180.27
569_S585_S0.5180.27
156_L756_S0.5150.27
611_K615_M0.5150.27
632_E687_E0.5140.27
143_R153_L0.5130.27
391_F399_K0.5130.27
224_F685_I0.5130.27
281_S488_M0.5120.27
369_Q388_D0.5120.27
329_I336_M0.5100.27
688_F735_M0.5090.27
584_I695_H0.5080.27
567_Q677_S0.5080.27
345_I353_A0.5080.27
608_V611_K0.5060.26
190_Y194_I0.5050.26
682_Y743_R0.5040.26
189_L197_Y0.5040.26
522_L525_Y0.5030.26
318_V332_I0.5020.26
528_V740_I0.5020.26
421_Q424_K0.5020.26
302_P310_L0.5010.26
592_L611_K0.5000.26
245_A254_A0.5000.26
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4i5sA 2 0.4616 100 0.717 Contact Map
4gczA 2 0.4525 100 0.727 Contact Map
3a0rA 2 0.4083 100 0.727 Contact Map
3ehhA 2 0.2549 100 0.739 Contact Map
4r39A 1 0.2562 100 0.742 Contact Map
4q20A 2 0.2718 100 0.743 Contact Map
4bixA 2 0.2731 100 0.746 Contact Map
2c2aA 2 0.2822 100 0.749 Contact Map
4mpcA 2 0.3563 100 0.752 Contact Map
3jz3A 2 0.1964 100 0.752 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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