COMP - BACSU - GREMLIN Contacts

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COMP - Sensor histidine kinase ComP

UniProt:	Q99027	Sequences: MKNLIKKFTIAVIVLSILYISYTTYISMNGIIIGTKIHKNDKSQFMIEEISESSYGQFVGLRQGDIILKINKEKPSDKHLKWGYLSHINSLDILRSGKKIHLKDFDLVTLNRPYSFFLFVLPLFFYFLSIICIFYILKVNKKRRSFAAYILILLLLDISIAYISAGGPFRGHIINRYINLFTFISSPILYLQFIQRYLGEIGKTFLNRISFLYIIPIFNLGIEFFQDYLQVDIDFLATLNLVSFATLTLFSFSAIYLHLNKYKYAEHSFILKLLILTNTLSFAPFLIFFVLPIIFTGNYIFPALASASLLVLIPFGLVYQFVANKMFDIEFILGRMRYYALLAMIPTLLIVGALVLFDVMDIQMNPVRQTVFFFVVMFAVFYFKEVMDFKFRLKRFSEKFNYQDSIFKYTQLMRGVTSLQQVFKELKNTILDVLLVSKAYTFEVTPDHKVIFLDKHEVGPDWNFYQEEFENVTSEIGKIIEVNQGFLMKVGERGGSSYVLLCLSNINTPRLTRDEISWLKTLSFYTSVSMENVLHIEELMEHLKDLKQEGTNPIWLKKLMFAIEEKQRSGLARDLHDSVLQDLISLKRQCELFLGDFKKDDNPCREEVQDKLVQMNEQMSDVISMTRETCHELRPQLLYDLGLVKALSKLVAQQQERVPFHIRLNTGRFTASLDLDSQLNLYRIIQEFLSNAVKHSQATDVLIMLISIQNKIVLHYEDDGVGFDQEKNTEHSMSMGLSGIKERVRALDGRLRIETSEGKGFKADIEIEL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	769 (606)
Sequences:	1011 (943)
Seq/√Len:	38.3

BACSU - COMP

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
535_H	539_L	4.248	1.00
696_S	719_D	4.209	1.00
539_L	542_H	3.952	1.00
684_I	743_R	3.820	1.00
696_S	699_T	3.502	1.00
532_N	535_H	3.312	1.00
186_S	190_Y	3.264	1.00
756_S	759_K	3.245	1.00
257_L	261_K	3.176	1.00
630_C	633_L	3.073	1.00
574_D	582_D	3.039	1.00
741_K	745_R	2.807	1.00
183_F	190_Y	2.775	1.00
536_I	539_L	2.716	1.00
717_E	762_K	2.684	1.00
699_T	719_D	2.656	1.00
684_I	744_V	2.612	1.00
535_H	542_H	2.580	1.00
650_L	689_L	2.562	1.00
740_I	743_R	2.549	1.00
685_I	714_L	2.546	1.00
740_I	751_L	2.542	1.00
744_V	765_I	2.542	1.00
744_V	749_G	2.514	1.00
743_R	747_L	2.464	1.00
647_L	685_I	2.449	1.00
627_R	633_L	2.422	1.00
580_L	584_I	2.399	1.00
515_E	518_W	2.383	1.00
535_H	538_E	2.367	1.00
183_F	186_S	2.323	1.00
718_D	722_G	2.290	1.00
538_E	542_H	2.287	1.00
564_E	567_Q	2.272	1.00
256_Y	260_N	2.266	1.00
572_A	581_Q	2.258	0.99
660_F	664_L	2.253	0.99
574_D	683_R	2.215	0.99
567_Q	695_H	2.202	0.99
581_Q	694_K	2.193	0.99
642_G	645_K	2.172	0.99
704_M	715_H	2.158	0.99
627_R	630_C	2.147	0.99
687_E	695_H	2.120	0.99
252_F	256_Y	2.093	0.99
711_K	766_E	2.069	0.99
573_R	732_S	2.051	0.99
568_R	695_H	2.047	0.99
384_K	388_D	2.044	0.99
573_R	687_E	2.042	0.99
430_I	434_L	2.030	0.99
619_M	683_R	2.030	0.99
566_K	569_S	2.023	0.99
683_R	686_Q	2.023	0.99
249_L	252_F	2.007	0.99
307_A	311_V	2.007	0.99
581_Q	588_R	2.004	0.99
573_R	734_S	1.988	0.99
125_F	129_S	1.977	0.99
581_Q	695_H	1.936	0.98
567_Q	570_G	1.932	0.98
538_E	541_E	1.931	0.98
179_N	182_T	1.927	0.98
403_Q	413_M	1.922	0.98
564_E	572_A	1.912	0.98
324_N	328_D	1.895	0.98
560_M	621_D	1.891	0.98
570_G	574_D	1.879	0.98
377_M	380_V	1.867	0.98
581_Q	584_I	1.862	0.98
530_M	533_V	1.841	0.98
749_G	767_I	1.827	0.98
523_S	528_V	1.825	0.98
558_K	562_A	1.817	0.98
565_E	568_R	1.816	0.98
530_M	539_L	1.814	0.98
683_R	747_L	1.813	0.98
306_S	311_V	1.798	0.97
564_E	568_R	1.779	0.97
639_Y	678_Q	1.777	0.97
724_D	757_E	1.768	0.97
523_S	527_S	1.766	0.97
304_L	311_V	1.758	0.97
688_F	740_I	1.753	0.97
755_T	761_F	1.752	0.97
588_R	683_R	1.748	0.97
687_E	732_S	1.747	0.97
478_K	482_V	1.747	0.97
532_N	539_L	1.746	0.97
557_K	560_M	1.732	0.97
575_L	625_M	1.730	0.97
572_A	694_K	1.727	0.97
567_Q	572_A	1.726	0.97
580_L	588_R	1.721	0.97
130_I	133_I	1.721	0.97
427_K	439_A	1.701	0.96
568_R	581_Q	1.698	0.96
643_L	712_I	1.698	0.96
372_F	380_V	1.691	0.96
374_F	380_V	1.689	0.96
533_V	539_L	1.677	0.96
564_E	581_Q	1.672	0.96
130_I	134_F	1.670	0.96
303_A	306_S	1.668	0.96
564_E	695_H	1.665	0.96
257_L	260_N	1.659	0.96
684_I	740_I	1.654	0.96
445_T	449_K	1.653	0.96
723_F	737_L	1.645	0.96
692_A	701_V	1.640	0.95
182_T	186_S	1.639	0.95
567_Q	581_Q	1.636	0.95
304_L	307_A	1.594	0.95
254_A	258_H	1.592	0.95
209_I	213_Y	1.588	0.95
715_H	764_D	1.580	0.94
252_F	258_H	1.572	0.94
252_F	257_L	1.570	0.94
248_T	256_Y	1.562	0.94
580_L	694_K	1.554	0.94
521_T	528_V	1.544	0.94
689_L	701_V	1.543	0.94
565_E	570_G	1.540	0.94
372_F	376_V	1.537	0.94
572_A	695_H	1.534	0.94
186_S	197_Y	1.521	0.93
718_D	760_G	1.520	0.93
663_R	700_D	1.502	0.93
334_G	341_L	1.497	0.93
753_I	761_F	1.488	0.92
182_T	190_Y	1.484	0.92
567_Q	687_E	1.483	0.92
452_F	455_K	1.479	0.92
532_N	538_E	1.478	0.92
335_R	343_A	1.476	0.92
179_N	190_Y	1.473	0.92
323_A	327_F	1.466	0.92
735_M	739_G	1.456	0.92
249_L	253_S	1.455	0.92
586_L	683_R	1.454	0.92
477_G	480_I	1.439	0.91
485_G	489_K	1.437	0.91
487_L	501_L	1.428	0.91
688_F	765_I	1.426	0.91
465_Y	475_E	1.422	0.91
574_D	618_Q	1.420	0.91
372_F	384_K	1.418	0.90
565_E	581_Q	1.415	0.90
567_Q	683_R	1.411	0.90
306_S	313_I	1.407	0.90
574_D	686_Q	1.407	0.90
140_N	143_R	1.398	0.90
581_Q	585_S	1.398	0.90
380_V	384_K	1.396	0.90
214_I	218_F	1.392	0.90
427_K	430_I	1.391	0.90
129_S	133_I	1.388	0.90
728_N	753_I	1.387	0.89
753_I	763_A	1.378	0.89
348_L	351_V	1.372	0.89
564_E	694_K	1.370	0.89
567_Q	573_R	1.366	0.89
568_R	694_K	1.358	0.88
625_M	632_E	1.358	0.88
582_D	739_G	1.355	0.88
568_R	572_A	1.355	0.88
687_E	739_G	1.355	0.88
529_S	535_H	1.344	0.88
606_E	609_Q	1.343	0.88
580_L	585_S	1.332	0.87
755_T	759_K	1.323	0.87
754_E	762_K	1.322	0.87
567_Q	694_K	1.322	0.87
724_D	727_K	1.321	0.87
683_R	743_R	1.319	0.87
582_D	687_E	1.319	0.87
534_L	538_E	1.317	0.87
570_G	626_T	1.316	0.87
307_A	310_L	1.315	0.87
752_R	764_D	1.311	0.87
324_N	327_F	1.309	0.87
252_F	260_N	1.307	0.86
580_L	591_E	1.307	0.86
682_Y	686_Q	1.304	0.86
361_D	365_N	1.298	0.86
582_D	723_F	1.294	0.86
643_L	714_L	1.292	0.86
567_Q	571_L	1.291	0.86
564_E	570_G	1.289	0.86
680_N	743_R	1.267	0.85
573_R	677_S	1.265	0.85
567_Q	580_L	1.247	0.84
695_H	733_M	1.241	0.83
248_T	258_H	1.238	0.83
569_S	584_I	1.232	0.83
676_D	747_L	1.227	0.83
127_F	133_I	1.226	0.83
687_E	740_I	1.219	0.82
680_N	695_H	1.217	0.82
325_K	328_D	1.215	0.82
703_I	744_V	1.214	0.82
533_V	536_I	1.211	0.82
321_F	324_N	1.211	0.82
622_V	694_K	1.208	0.82
568_R	743_R	1.207	0.82
303_A	307_A	1.206	0.82
564_E	580_L	1.198	0.81
580_L	587_K	1.197	0.81
427_K	440_Y	1.191	0.81
426_L	433_V	1.189	0.81
334_G	343_A	1.186	0.81
193_F	198_L	1.179	0.80
377_M	388_D	1.179	0.80
532_N	536_I	1.178	0.80
570_G	695_H	1.172	0.80
256_Y	261_K	1.172	0.80
258_H	261_K	1.171	0.80
303_A	311_V	1.171	0.80
703_I	716_Y	1.171	0.80
427_K	431_L	1.163	0.79
248_T	252_F	1.160	0.79
183_F	193_F	1.158	0.79
183_F	187_P	1.155	0.79
348_L	355_V	1.151	0.78
529_S	538_E	1.145	0.78
507_N	515_E	1.145	0.78
187_P	190_Y	1.144	0.78
618_Q	625_M	1.139	0.78
369_Q	375_V	1.138	0.78
324_N	332_I	1.132	0.77
665_N	704_M	1.131	0.77
380_V	389_F	1.129	0.77
574_D	581_Q	1.124	0.77
150_I	261_K	1.124	0.77
521_T	527_S	1.123	0.77
618_Q	626_T	1.123	0.77
565_E	683_R	1.123	0.77
581_Q	623_I	1.122	0.77
571_L	695_H	1.121	0.77
687_E	763_A	1.120	0.77
674_D	681_L	1.120	0.77
755_T	758_G	1.116	0.76
246_T	260_N	1.116	0.76
687_E	743_R	1.115	0.76
168_P	171_G	1.114	0.76
427_K	433_V	1.114	0.76
478_K	481_E	1.113	0.76
623_I	627_R	1.112	0.76
565_E	580_L	1.110	0.76
573_R	763_A	1.108	0.76
304_L	308_S	1.103	0.75
401_N	410_T	1.102	0.75
452_F	457_E	1.099	0.75
713_V	766_E	1.099	0.75
677_S	732_S	1.097	0.75
570_G	694_K	1.096	0.75
751_L	763_A	1.094	0.75
589_Q	592_L	1.092	0.75
322_V	327_F	1.092	0.75
681_L	685_I	1.091	0.75
179_N	186_S	1.088	0.74
121_L	133_I	1.077	0.74
186_S	198_L	1.074	0.73
532_N	542_H	1.073	0.73
154_L	162_Y	1.068	0.73
591_E	594_L	1.066	0.73
179_N	183_F	1.065	0.73
126_Y	130_I	1.064	0.73
566_K	570_G	1.062	0.73
190_Y	198_L	1.059	0.72
565_E	571_L	1.058	0.72
252_F	255_I	1.054	0.72
681_L	765_I	1.054	0.72
573_R	695_H	1.053	0.72
427_K	436_V	1.051	0.72
621_D	629_T	1.050	0.72
749_G	768_E	1.048	0.72
586_L	592_L	1.047	0.72
574_D	588_R	1.045	0.71
453_L	456_H	1.044	0.71
321_F	325_K	1.043	0.71
568_R	687_E	1.043	0.71
402_Y	405_S	1.043	0.71
574_D	739_G	1.035	0.71
574_D	622_V	1.034	0.71
722_G	760_G	1.033	0.70
380_V	383_F	1.032	0.70
587_K	619_M	1.030	0.70
680_N	683_R	1.027	0.70
580_L	586_L	1.024	0.70
476_I	490_V	1.022	0.70
368_R	381_F	1.020	0.69
567_Q	743_R	1.019	0.69
588_R	619_M	1.018	0.69
692_A	696_S	1.018	0.69
179_N	193_F	1.018	0.69
683_R	739_G	1.018	0.69
581_Q	589_Q	1.015	0.69
565_E	695_H	1.014	0.69
574_D	586_L	1.010	0.69
368_R	372_F	1.008	0.69
483_N	486_F	1.006	0.68
687_E	737_L	1.004	0.68
525_Y	528_V	1.000	0.68
627_R	632_E	1.000	0.68
527_S	531_E	0.999	0.68
512_T	515_E	0.997	0.68
308_S	311_V	0.995	0.68
588_R	592_L	0.994	0.67
334_G	344_M	0.993	0.67
427_K	434_L	0.989	0.67
192_Q	292_P	0.989	0.67
328_D	332_I	0.989	0.67
695_H	739_G	0.986	0.67
426_L	436_V	0.985	0.67
580_L	739_G	0.985	0.67
650_L	686_Q	0.983	0.67
614_Q	622_V	0.981	0.66
581_Q	586_L	0.981	0.66
340_A	344_M	0.979	0.66
584_I	588_R	0.978	0.66
580_L	695_H	0.978	0.66
683_R	761_F	0.976	0.66
248_T	255_I	0.975	0.66
333_L	341_L	0.973	0.66
635_P	646_A	0.973	0.66
163_I	286_L	0.969	0.65
480_I	489_K	0.968	0.65
695_H	743_R	0.968	0.65
484_Q	488_M	0.966	0.65
219_N	716_Y	0.966	0.65
426_L	434_L	0.965	0.65
690_S	694_K	0.963	0.65
583_L	592_L	0.962	0.65
584_I	591_E	0.959	0.65
571_L	719_D	0.957	0.65
564_E	585_S	0.957	0.65
403_Q	406_I	0.956	0.64
188_I	224_F	0.955	0.64
569_S	696_S	0.954	0.64
575_L	653_Q	0.954	0.64
622_V	625_M	0.952	0.64
444_V	447_D	0.952	0.64
581_Q	592_L	0.952	0.64
488_M	491_G	0.948	0.64
674_D	677_S	0.946	0.64
182_T	189_L	0.945	0.64
645_K	678_Q	0.944	0.63
125_F	128_L	0.944	0.63
322_V	325_K	0.943	0.63
142_K	145_S	0.939	0.63
414_R	427_K	0.938	0.63
688_F	694_K	0.936	0.63
160_I	214_I	0.935	0.63
190_Y	193_F	0.933	0.63
636_Q	684_I	0.932	0.62
623_I	633_L	0.931	0.62
340_A	343_A	0.930	0.62
596_D	599_K	0.929	0.62
384_K	389_F	0.929	0.62
663_R	702_L	0.927	0.62
630_C	695_H	0.926	0.62
371_V	382_Y	0.924	0.62
402_Y	407_F	0.924	0.62
400_F	515_E	0.922	0.62
530_M	542_H	0.921	0.61
341_L	344_M	0.921	0.61
210_S	218_F	0.920	0.61
222_I	265_A	0.919	0.61
570_G	622_V	0.919	0.61
483_N	487_L	0.919	0.61
131_I	136_I	0.919	0.61
647_L	664_L	0.917	0.61
642_G	646_A	0.915	0.61
398_E	409_Y	0.914	0.61
646_A	682_Y	0.910	0.61
583_L	589_Q	0.908	0.60
689_L	703_I	0.907	0.60
335_R	339_Y	0.906	0.60
308_S	315_F	0.905	0.60
131_I	149_Y	0.904	0.60
431_L	439_A	0.904	0.60
575_L	733_M	0.901	0.60
583_L	587_K	0.901	0.60
570_G	580_L	0.898	0.60
568_R	573_R	0.898	0.60
581_Q	619_M	0.897	0.59
129_S	134_F	0.896	0.59
186_S	193_F	0.894	0.59
308_S	312_L	0.894	0.59
421_Q	427_K	0.894	0.59
570_G	733_M	0.893	0.59
212_L	242_V	0.893	0.59
640_D	673_L	0.893	0.59
336_M	343_A	0.892	0.59
176_R	180_L	0.892	0.59
208_R	757_E	0.891	0.59
657_R	660_F	0.891	0.59
568_R	582_D	0.888	0.59
571_L	743_R	0.887	0.59
502_C	505_N	0.887	0.59
706_I	715_H	0.885	0.58
691_N	718_D	0.884	0.58
360_M	363_Q	0.883	0.58
570_G	581_Q	0.883	0.58
565_E	572_A	0.881	0.58
315_F	321_F	0.881	0.58
580_L	589_Q	0.879	0.58
696_S	701_V	0.875	0.58
393_L	402_Y	0.873	0.57
498_Y	502_C	0.870	0.57
677_S	687_E	0.869	0.57
476_I	479_I	0.866	0.57
644_V	705_L	0.864	0.57
567_Q	696_S	0.863	0.56
676_D	681_L	0.862	0.56
485_G	488_M	0.862	0.56
689_L	692_A	0.860	0.56
400_F	403_Q	0.859	0.56
329_I	335_R	0.858	0.56
687_E	723_F	0.857	0.56
312_L	315_F	0.856	0.56
423_F	430_I	0.856	0.56
723_F	734_S	0.856	0.56
563_I	566_K	0.856	0.56
583_L	630_C	0.854	0.56
355_V	359_V	0.853	0.56
477_G	482_V	0.853	0.56
327_F	332_I	0.853	0.56
586_L	589_Q	0.852	0.55
345_I	348_L	0.852	0.55
256_Y	259_L	0.852	0.55
361_D	364_M	0.852	0.55
381_F	385_E	0.850	0.55
406_I	413_M	0.849	0.55
523_S	526_T	0.848	0.55
405_S	408_K	0.847	0.55
590_C	615_M	0.846	0.55
567_Q	625_M	0.846	0.55
182_T	185_S	0.845	0.55
425_E	429_T	0.844	0.55
732_S	763_A	0.843	0.55
253_S	257_L	0.841	0.55
533_V	540_M	0.840	0.54
255_I	271_L	0.840	0.54
424_K	427_K	0.839	0.54
626_T	747_L	0.839	0.54
734_S	768_E	0.837	0.54
724_D	753_I	0.837	0.54
702_L	717_E	0.833	0.54
427_K	437_S	0.832	0.54
321_F	327_F	0.830	0.54
211_F	217_I	0.830	0.54
567_Q	584_I	0.830	0.54
581_Q	587_K	0.829	0.53
150_I	157_D	0.827	0.53
478_K	483_N	0.827	0.53
158_I	161_A	0.826	0.53
660_F	666_T	0.825	0.53
618_Q	683_R	0.824	0.53
302_P	307_A	0.823	0.53
404_D	408_K	0.822	0.53
627_R	635_P	0.819	0.53
720_G	736_G	0.818	0.52
144_R	149_Y	0.817	0.52
572_A	625_M	0.817	0.52
440_Y	453_L	0.815	0.52
528_V	533_V	0.815	0.52
674_D	763_A	0.814	0.52
188_I	192_Q	0.811	0.52
565_E	569_S	0.811	0.52
509_P	515_E	0.810	0.52
573_R	735_M	0.809	0.52
523_S	529_S	0.808	0.52
530_M	535_H	0.808	0.52
484_Q	489_K	0.806	0.51
585_S	588_R	0.804	0.51
426_L	430_I	0.804	0.51
591_E	694_K	0.804	0.51
517_S	520_K	0.804	0.51
249_L	258_H	0.802	0.51
564_E	588_R	0.802	0.51
635_P	638_L	0.801	0.51
325_K	332_I	0.800	0.51
329_I	332_I	0.799	0.51
685_I	701_V	0.798	0.51
677_S	680_N	0.795	0.50
635_P	682_Y	0.795	0.50
580_L	630_C	0.793	0.50
567_Q	732_S	0.791	0.50
560_M	626_T	0.789	0.50
694_K	743_R	0.788	0.50
687_E	734_S	0.788	0.50
251_S	254_A	0.784	0.49
557_K	563_I	0.784	0.49
565_E	747_L	0.782	0.49
565_E	630_C	0.781	0.49
564_E	626_T	0.780	0.49
572_A	632_E	0.779	0.49
587_K	629_T	0.778	0.49
557_K	564_E	0.778	0.49
398_E	406_I	0.777	0.49
680_N	740_I	0.777	0.49
568_R	733_M	0.777	0.49
571_L	690_S	0.777	0.49
324_N	341_L	0.775	0.49
276_L	349_L	0.775	0.49
584_I	623_I	0.773	0.48
336_M	341_L	0.772	0.48
380_V	385_E	0.772	0.48
405_S	409_Y	0.771	0.48
268_S	350_I	0.771	0.48
723_F	735_M	0.770	0.48
402_Y	406_I	0.769	0.48
688_F	763_A	0.769	0.48
687_E	733_M	0.768	0.48
372_F	381_F	0.765	0.48
570_G	687_E	0.764	0.48
371_V	381_F	0.763	0.48
535_H	540_M	0.762	0.47
688_F	743_R	0.760	0.47
327_F	341_L	0.760	0.47
607_E	610_D	0.760	0.47
692_A	732_S	0.758	0.47
372_F	377_M	0.755	0.47
572_A	591_E	0.755	0.47
127_F	135_Y	0.753	0.47
310_L	314_P	0.751	0.46
528_V	535_H	0.750	0.46
498_Y	527_S	0.749	0.46
573_R	582_D	0.749	0.46
582_D	737_L	0.746	0.46
377_M	381_F	0.745	0.46
371_V	380_V	0.743	0.46
331_F	335_R	0.743	0.46
283_A	287_I	0.743	0.46
484_Q	487_L	0.742	0.46
621_D	624_S	0.742	0.46
529_S	533_V	0.742	0.46
183_F	189_L	0.742	0.46
568_R	625_M	0.741	0.46
206_L	209_I	0.741	0.46
580_L	763_A	0.741	0.46
641_L	676_D	0.741	0.46
615_M	621_D	0.740	0.45
569_S	695_H	0.737	0.45
568_R	696_S	0.735	0.45
570_G	743_R	0.735	0.45
381_F	384_K	0.735	0.45
345_I	356_L	0.735	0.45
211_F	218_F	0.734	0.45
586_L	694_K	0.733	0.45
587_K	694_K	0.731	0.45
659_P	665_N	0.731	0.45
431_L	435_L	0.729	0.44
573_R	688_F	0.729	0.44
368_R	380_V	0.728	0.44
144_R	150_I	0.727	0.44
575_L	694_K	0.724	0.44
515_E	525_Y	0.722	0.44
742_E	745_R	0.722	0.44
336_M	340_A	0.722	0.44
678_Q	688_F	0.721	0.44
557_K	565_E	0.721	0.44
530_M	538_E	0.720	0.44
248_T	260_N	0.720	0.44
426_L	445_T	0.719	0.44
426_L	440_Y	0.717	0.43
422_V	427_K	0.717	0.43
581_Q	683_R	0.716	0.43
148_A	151_L	0.715	0.43
575_L	622_V	0.715	0.43
244_F	252_F	0.715	0.43
573_R	723_F	0.714	0.43
376_V	384_K	0.713	0.43
251_S	255_I	0.713	0.43
692_A	755_T	0.712	0.43
486_F	489_K	0.711	0.43
304_L	310_L	0.708	0.43
409_Y	767_I	0.706	0.42
736_G	749_G	0.706	0.42
571_L	696_S	0.705	0.42
633_L	683_R	0.705	0.42
327_F	330_E	0.704	0.42
632_E	683_R	0.702	0.42
569_S	732_S	0.702	0.42
501_L	505_N	0.702	0.42
426_L	438_K	0.701	0.42
507_N	511_L	0.701	0.42
332_I	343_A	0.700	0.42
611_K	622_V	0.700	0.42
360_M	365_N	0.699	0.42
184_I	192_Q	0.697	0.42
564_E	589_Q	0.696	0.42
335_R	350_I	0.694	0.41
625_M	630_C	0.693	0.41
286_L	312_L	0.693	0.41
477_G	481_E	0.692	0.41
680_N	739_G	0.691	0.41
301_F	307_A	0.691	0.41
335_R	341_L	0.690	0.41
489_K	493_R	0.689	0.41
384_K	387_M	0.688	0.41
345_I	357_F	0.688	0.41
448_H	452_F	0.686	0.41
677_S	763_A	0.686	0.41
408_K	411_Q	0.684	0.41
567_Q	761_F	0.683	0.40
570_G	738_S	0.683	0.40
282_F	575_L	0.682	0.40
505_N	515_E	0.682	0.40
708_I	711_K	0.680	0.40
325_K	335_R	0.680	0.40
479_I	487_L	0.679	0.40
635_P	642_G	0.679	0.40
691_N	736_G	0.678	0.40
557_K	567_Q	0.676	0.40
402_Y	410_T	0.676	0.40
634_R	742_E	0.675	0.40
653_Q	695_H	0.675	0.40
584_I	587_K	0.675	0.40
402_Y	409_Y	0.673	0.40
452_F	456_H	0.671	0.39
211_F	256_Y	0.670	0.39
241_L	245_A	0.669	0.39
542_H	557_K	0.669	0.39
192_Q	213_Y	0.668	0.39
511_L	539_L	0.668	0.39
185_S	377_M	0.668	0.39
438_K	503_L	0.667	0.39
567_Q	630_C	0.667	0.39
131_I	139_V	0.667	0.39
746_A	763_A	0.665	0.39
321_F	328_D	0.665	0.39
569_S	586_L	0.664	0.39
690_S	695_H	0.663	0.39
362_I	365_N	0.663	0.39
750_R	766_E	0.662	0.39
445_T	448_H	0.662	0.39
521_T	529_S	0.661	0.39
646_A	685_I	0.660	0.38
246_T	251_S	0.660	0.38
133_I	139_V	0.659	0.38
691_N	720_G	0.658	0.38
622_V	627_R	0.658	0.38
728_N	731_H	0.656	0.38
219_N	422_V	0.655	0.38
661_H	700_D	0.654	0.38
239_L	243_S	0.653	0.38
505_N	511_L	0.653	0.38
708_I	713_V	0.652	0.38
529_S	532_N	0.652	0.38
732_S	761_F	0.649	0.38
534_L	537_E	0.648	0.37
643_L	750_R	0.648	0.37
306_S	315_F	0.647	0.37
165_A	280_L	0.646	0.37
222_I	765_I	0.646	0.37
533_V	542_H	0.646	0.37
396_F	400_F	0.645	0.37
185_S	209_I	0.644	0.37
498_Y	505_N	0.643	0.37
586_L	622_V	0.643	0.37
127_F	130_I	0.642	0.37
324_N	343_A	0.642	0.37
328_D	335_R	0.641	0.37
206_L	278_N	0.641	0.37
629_T	633_L	0.641	0.37
683_R	695_H	0.640	0.37
453_L	457_E	0.639	0.37
393_L	398_E	0.639	0.37
451_I	454_D	0.638	0.37
311_V	315_F	0.637	0.37
528_V	532_N	0.635	0.36
521_T	525_Y	0.635	0.36
569_S	699_T	0.635	0.36
127_F	139_V	0.633	0.36
582_D	588_R	0.633	0.36
401_N	405_S	0.633	0.36
178_I	643_L	0.632	0.36
186_S	189_L	0.632	0.36
386_V	390_K	0.631	0.36
612_L	633_L	0.630	0.36
700_D	719_D	0.630	0.36
745_R	750_R	0.630	0.36
515_E	526_T	0.629	0.36
521_T	524_F	0.629	0.36
570_G	634_R	0.628	0.36
423_F	441_T	0.627	0.36
137_L	262_Y	0.627	0.36
367_V	371_V	0.627	0.36
695_H	746_A	0.626	0.36
574_D	723_F	0.626	0.36
249_L	349_L	0.626	0.36
428_N	432_D	0.625	0.36
715_H	762_K	0.624	0.35
582_D	586_L	0.624	0.35
581_Q	680_N	0.623	0.35
420_Q	427_K	0.622	0.35
523_S	530_M	0.622	0.35
687_E	738_S	0.622	0.35
500_L	503_L	0.622	0.35
154_L	158_I	0.621	0.35
573_R	580_L	0.621	0.35
350_I	384_K	0.620	0.35
249_L	256_Y	0.620	0.35
249_L	257_L	0.619	0.35
181_F	426_L	0.619	0.35
650_L	682_Y	0.618	0.35
238_T	241_L	0.618	0.35
588_R	614_Q	0.617	0.35
645_K	648_S	0.617	0.35
619_M	623_I	0.616	0.35
210_S	219_N	0.615	0.35
396_F	402_Y	0.615	0.35
644_V	648_S	0.615	0.35
323_A	328_D	0.615	0.35
243_S	248_T	0.614	0.35
184_I	194_I	0.613	0.35
484_Q	491_G	0.613	0.35
167_G	170_R	0.611	0.34
640_D	675_L	0.611	0.34
528_V	536_I	0.610	0.34
348_L	357_F	0.609	0.34
685_I	729_T	0.609	0.34
332_I	336_M	0.609	0.34
709_Q	716_Y	0.608	0.34
323_A	343_A	0.607	0.34
582_D	763_A	0.606	0.34
156_L	159_S	0.606	0.34
752_R	766_E	0.606	0.34
429_T	433_V	0.605	0.34
327_F	335_R	0.604	0.34
582_D	732_S	0.604	0.34
525_Y	530_M	0.604	0.34
433_V	440_Y	0.604	0.34
676_D	695_H	0.603	0.34
573_R	581_Q	0.602	0.34
283_A	430_I	0.601	0.34
563_I	629_T	0.601	0.34
344_M	355_V	0.601	0.34
399_K	402_Y	0.601	0.34
180_L	184_I	0.600	0.34
582_D	695_H	0.599	0.33
570_G	741_K	0.598	0.33
450_V	455_K	0.598	0.33
429_T	529_S	0.597	0.33
413_M	426_L	0.596	0.33
128_L	136_I	0.596	0.33
402_Y	413_M	0.596	0.33
324_N	334_G	0.594	0.33
688_F	722_G	0.594	0.33
567_Q	763_A	0.593	0.33
570_G	633_L	0.591	0.33
705_L	712_I	0.591	0.33
628_E	742_E	0.591	0.33
339_Y	343_A	0.591	0.33
239_L	712_I	0.589	0.33
572_A	623_I	0.589	0.33
174_I	367_V	0.588	0.33
643_L	674_D	0.587	0.32
253_S	368_R	0.586	0.32
149_Y	748_D	0.585	0.32
514_D	525_Y	0.584	0.32
167_G	172_H	0.583	0.32
126_Y	137_L	0.582	0.32
475_E	481_E	0.581	0.32
559_L	562_A	0.581	0.32
589_Q	694_K	0.580	0.32
368_R	376_V	0.580	0.32
584_I	696_S	0.580	0.32
682_Y	739_G	0.579	0.32
625_M	633_L	0.578	0.32
718_D	736_G	0.578	0.32
427_K	519_L	0.577	0.32
566_K	587_K	0.576	0.32
399_K	406_I	0.576	0.32
147_A	432_D	0.576	0.32
305_A	319_Y	0.575	0.32
694_K	739_G	0.573	0.31
516_I	519_L	0.573	0.31
618_Q	753_I	0.573	0.31
674_D	687_E	0.572	0.31
179_N	189_L	0.572	0.31
426_L	441_T	0.571	0.31
369_Q	376_V	0.571	0.31
413_M	433_V	0.571	0.31
519_L	525_Y	0.571	0.31
567_Q	589_Q	0.571	0.31
312_L	317_L	0.571	0.31
125_F	135_Y	0.570	0.31
563_I	622_V	0.570	0.31
573_R	674_D	0.570	0.31
403_Q	412_L	0.569	0.31
395_R	400_F	0.567	0.31
522_L	528_V	0.566	0.31
695_H	732_S	0.565	0.31
399_K	410_T	0.565	0.31
269_F	373_F	0.564	0.31
301_F	308_S	0.564	0.31
408_K	425_E	0.562	0.31
497_S	716_Y	0.562	0.31
328_D	341_L	0.561	0.30
306_S	328_D	0.561	0.30
157_D	161_A	0.559	0.30
632_E	653_Q	0.558	0.30
149_Y	153_L	0.557	0.30
568_R	626_T	0.556	0.30
303_A	325_K	0.555	0.30
589_Q	625_M	0.555	0.30
657_R	661_H	0.555	0.30
237_A	241_L	0.555	0.30
739_G	763_A	0.554	0.30
568_R	584_I	0.554	0.30
169_F	173_I	0.553	0.30
570_G	582_D	0.553	0.30
524_F	528_V	0.553	0.30
301_F	311_V	0.552	0.30
285_F	288_F	0.552	0.30
134_F	372_F	0.552	0.30
676_D	749_G	0.551	0.30
437_S	444_V	0.550	0.30
572_A	583_L	0.550	0.30
242_V	744_V	0.550	0.30
245_A	260_N	0.549	0.30
572_A	580_L	0.549	0.30
245_A	276_L	0.549	0.30
564_E	584_I	0.549	0.30
327_F	343_A	0.547	0.29
314_P	328_D	0.546	0.29
141_K	144_R	0.546	0.29
695_H	740_I	0.546	0.29
425_E	444_V	0.545	0.29
573_R	740_I	0.544	0.29
301_F	306_S	0.543	0.29
494_G	501_L	0.542	0.29
192_Q	714_L	0.542	0.29
381_F	388_D	0.542	0.29
319_Y	424_K	0.541	0.29
250_F	757_E	0.541	0.29
374_F	379_A	0.541	0.29
694_K	740_I	0.541	0.29
145_S	148_A	0.540	0.29
332_I	335_R	0.538	0.29
572_A	582_D	0.538	0.29
332_I	341_L	0.537	0.29
352_G	355_V	0.537	0.29
606_E	610_D	0.537	0.29
565_E	633_L	0.536	0.29
571_L	667_G	0.535	0.29
594_L	607_E	0.535	0.29
413_M	440_Y	0.535	0.29
119_F	206_L	0.535	0.29
570_G	583_L	0.535	0.29
181_F	188_I	0.534	0.28
345_I	710_N	0.532	0.28
613_V	765_I	0.532	0.28
306_S	309_L	0.530	0.28
328_D	334_G	0.530	0.28
408_K	412_L	0.530	0.28
373_F	376_V	0.529	0.28
580_L	687_E	0.529	0.28
525_Y	529_S	0.529	0.28
281_S	645_K	0.528	0.28
584_I	633_L	0.528	0.28
390_K	393_L	0.528	0.28
487_L	490_V	0.527	0.28
185_S	212_L	0.526	0.28
122_P	135_Y	0.525	0.28
217_I	345_I	0.525	0.28
633_L	646_A	0.525	0.28
573_R	593_F	0.525	0.28
565_E	694_K	0.524	0.28
205_F	716_Y	0.524	0.28
564_E	746_A	0.522	0.28
575_L	629_T	0.521	0.28
632_E	733_M	0.521	0.28
720_G	749_G	0.520	0.27
448_H	453_L	0.520	0.27
581_Q	739_G	0.518	0.27
437_S	440_Y	0.518	0.27
565_E	742_E	0.518	0.27
177_Y	180_L	0.518	0.27
142_K	225_F	0.518	0.27
569_S	585_S	0.518	0.27
156_L	756_S	0.515	0.27
611_K	615_M	0.515	0.27
632_E	687_E	0.514	0.27
143_R	153_L	0.513	0.27
391_F	399_K	0.513	0.27
224_F	685_I	0.513	0.27
281_S	488_M	0.512	0.27
369_Q	388_D	0.512	0.27
329_I	336_M	0.510	0.27
688_F	735_M	0.509	0.27
584_I	695_H	0.508	0.27
567_Q	677_S	0.508	0.27
345_I	353_A	0.508	0.27
608_V	611_K	0.506	0.26
190_Y	194_I	0.505	0.26
682_Y	743_R	0.504	0.26
189_L	197_Y	0.504	0.26
522_L	525_Y	0.503	0.26
318_V	332_I	0.502	0.26
528_V	740_I	0.502	0.26
421_Q	424_K	0.502	0.26
302_P	310_L	0.501	0.26
592_L	611_K	0.500	0.26
245_A	254_A	0.500	0.26

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.4616	100	0.717	Contact Map
4gczA	2	0.4525	100	0.727	Contact Map
3a0rA	2	0.4083	100	0.727	Contact Map
3ehhA	2	0.2549	100	0.739	Contact Map
4r39A	1	0.2562	100	0.742	Contact Map
4q20A	2	0.2718	100	0.743	Contact Map
4bixA	2	0.2731	100	0.746	Contact Map
2c2aA	2	0.2822	100	0.749	Contact Map
4mpcA	2	0.3563	100	0.752	Contact Map
3jz3A	2	0.1964	100	0.752	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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