GREMLIN Database
YGZB - UPF0295 protein YgzB
UniProt: Q7WY74 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 117 (111)
Sequences: 160 (83)
Seq/√Len: 7.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
25_I49_S4.5260.99
29_G58_F2.8590.84
10_K13_T2.3990.71
24_I42_F2.2660.67
24_I40_S2.2280.66
87_M93_E2.1350.62
5_S10_K2.0220.58
14_F56_V1.9740.56
17_S21_V1.9380.54
21_V49_S1.9210.54
78_E90_H1.8710.52
67_A113_K1.8170.49
51_G63_L1.8110.49
55_V74_G1.8080.49
44_I112_K1.7690.47
76_D99_K1.7450.46
87_M107_D1.5940.40
35_S38_L1.5690.39
62_M66_K1.5670.39
48_L70_V1.5590.39
19_V50_I1.5140.37
3_K58_F1.4910.36
47_L70_V1.4590.35
25_I66_K1.4530.35
104_K110_Y1.4430.35
24_I35_S1.4390.35
58_F65_T1.4170.34
108_E112_K1.4110.34
28_I56_V1.3990.33
24_I28_I1.3600.32
71_I76_D1.3380.31
81_V99_K1.3300.31
23_F50_I1.3240.30
10_K74_G1.3240.30
26_M95_L1.3110.30
55_V65_T1.2970.30
8_I96_T1.2960.29
96_T101_L1.2850.29
15_A20_F1.2840.29
23_F56_V1.2520.28
14_F23_F1.2340.27
67_A77_K1.2240.27
41_L44_I1.2170.27
76_D90_H1.2020.26
74_G93_E1.1900.26
69_R78_E1.1740.26
81_V108_E1.1690.25
8_I101_L1.1650.25
13_T17_S1.1530.25
25_I51_G1.1530.25
15_A27_Y1.1460.25
39_S67_A1.1440.25
54_T78_E1.1270.24
84_V107_D1.1140.24
52_L90_H1.0990.23
17_S93_E1.0900.23
49_S93_E1.0900.23
21_V37_L1.0530.22
48_L51_G1.0530.22
33_K77_K1.0490.22
28_I51_G1.0360.22
59_W68_V1.0340.21
30_I47_L1.0310.21
84_V103_G1.0310.21
102_E106_F1.0250.21
14_F60_I1.0250.21
9_N60_I0.9790.20
23_F47_L0.9630.20
15_A66_K0.9480.19
22_G98_D0.9240.19
94_P103_G0.9230.19
6_S63_L0.9110.18
21_V45_L0.9070.18
40_S44_I0.9060.18
47_L54_T0.8900.18
17_S81_V0.8890.18
11_I32_F0.8720.17
63_L81_V0.8450.17
4_Y89_M0.8430.17
37_L112_K0.8410.17
11_I14_F0.8350.17
44_I93_E0.8310.16
36_V109_S0.8160.16
6_S90_H0.8110.16
30_I43_M0.8020.16
25_I100_G0.8010.16
24_I32_F0.7970.16
87_M92_R0.7950.16
38_L112_K0.7940.16
28_I81_V0.7930.16
29_G39_S0.7930.16
6_S69_R0.7840.15
5_S108_E0.7800.15
24_I37_L0.7600.15
54_T105_E0.7540.15
41_L78_E0.7530.15
76_D100_G0.7510.15
21_V30_I0.7490.15
41_L81_V0.7300.14
37_L41_L0.7240.14
96_T103_G0.7230.14
27_Y94_P0.7180.14
76_D92_R0.7180.14
21_V56_V0.7090.14
23_F87_M0.7090.14
68_V97_L0.7040.14
47_L78_E0.6970.14
42_F45_L0.6940.14
34_E43_M0.6880.13
45_L82_L0.6850.13
36_V112_K0.6840.13
13_T52_L0.6800.13
8_I11_I0.6770.13
59_W99_K0.6770.13
4_Y108_E0.6760.13
35_S40_S0.6740.13
103_G111_N0.6660.13
103_G106_F0.6610.13
17_S56_V0.6590.13
28_I37_L0.6530.13
5_S60_I0.6510.13
85_V93_E0.6470.13
5_S9_N0.6450.13
106_F111_N0.6370.13
37_L52_L0.6300.12
34_E38_L0.6180.12
82_L96_T0.6170.12
48_L69_R0.6060.12
30_I78_E0.6060.12
42_F47_L0.6050.12
37_L100_G0.6050.12
48_L56_V0.6050.12
6_S30_I0.5980.12
67_A95_L0.5970.12
30_I56_V0.5940.12
50_I66_K0.5940.12
23_F76_D0.5920.12
21_V25_I0.5910.12
50_I77_K0.5750.11
28_I45_L0.5730.11
81_V112_K0.5690.11
5_S49_S0.5660.11
78_E109_S0.5650.11
85_V96_T0.5560.11
38_L52_L0.5540.11
45_L92_R0.5530.11
62_M113_K0.5530.11
29_G38_L0.5510.11
6_S99_K0.5510.11
30_I41_L0.5450.11
11_I60_I0.5410.11
68_V105_E0.5390.11
44_I76_D0.5370.11
19_V47_L0.5340.11
94_P106_F0.5340.11
31_F93_E0.5300.11
56_V71_I0.5260.11
32_F68_V0.5230.11
22_G67_A0.5220.11
31_F70_V0.5180.11
43_M107_D0.5160.11
5_S89_M0.5150.11
36_V40_S0.5120.10
109_S113_K0.5090.10
31_F35_S0.5040.10
69_R97_L0.5000.10
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4bbrM 1 0.4103 81.1 0.924 Contact Map
4qiwP 1 0.3248 79.9 0.925 Contact Map
3k1fM 1 0.4103 76.7 0.927 Contact Map
3wwlA 1 0.3504 74.8 0.929 Contact Map
3o9xA 2 0.4188 64.8 0.933 Contact Map
2apoB 1 0.4017 55.1 0.937 Contact Map
1pftA 1 0.3761 48.1 0.94 Contact Map
4aybP 1 0.3333 47.6 0.94 Contact Map
4e2xA 1 0.4103 44.6 0.941 Contact Map
3ga8A 1 0.4017 37.4 0.944 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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