GREMLIN Database
SPSL - Spore coat polysaccharide biosynthesis protein SpsL
UniProt: Q7WY56 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 151 (143)
Sequences: 4233 (2574)
Seq/√Len: 215.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
26_D33_H3.4161.00
66_H88_Y3.3471.00
111_G115_L2.9921.00
9_K95_M2.8021.00
126_N131_D2.7531.00
54_E133_K2.6761.00
67_A117_I2.6741.00
47_I108_R2.4281.00
50_F104_A2.4081.00
57_D98_L2.3791.00
68_Q86_V2.3351.00
37_A120_F2.3311.00
40_S107_Y2.2991.00
27_D124_S2.2571.00
57_D122_T2.1331.00
64_T91_E2.0811.00
44_P113_T2.0651.00
101_K122_T1.9901.00
63_P118_I1.9761.00
64_T116_T1.9141.00
64_T114_P1.9101.00
7_V95_M1.9051.00
41_K116_T1.8381.00
39_W116_T1.7971.00
52_Y133_K1.7551.00
66_H111_G1.7551.00
90_G93_N1.6991.00
74_L104_A1.6851.00
57_D101_K1.6841.00
68_Q147_N1.6781.00
5_V71_L1.6781.00
39_W61_F1.6291.00
7_V87_Y1.6291.00
66_H90_G1.6021.00
50_F106_G1.5581.00
5_V85_D1.4931.00
12_K94_P1.4731.00
25_R28_E1.4681.00
32_E98_L1.4431.00
19_F41_K1.3981.00
67_A115_L1.3821.00
109_V115_L1.3621.00
108_R148_T1.3361.00
128_D131_D1.3231.00
135_I142_I1.2771.00
71_L85_D1.2771.00
101_K123_M1.2521.00
100_P103_V1.2401.00
32_E101_K1.2341.00
22_E25_R1.2271.00
55_K131_D1.1891.00
70_V146_W1.1791.00
104_A135_I1.1571.00
87_Y97_L1.1351.00
52_Y104_A1.1321.00
111_G114_P1.0951.00
108_R147_N1.0901.00
50_F72_Y1.0891.00
25_R124_S1.0831.00
69_V105_H1.0781.00
20_F40_S1.0731.00
41_K114_P1.0721.00
54_E131_D1.0691.00
44_P111_G1.0471.00
39_W118_I1.0381.00
87_Y95_M1.0261.00
38_S121_T1.0041.00
82_G141_T1.0041.00
19_F39_W0.9971.00
22_E36_Q0.9891.00
75_R103_V0.9851.00
23_L37_A0.9801.00
52_Y74_L0.9661.00
22_E56_Q0.9641.00
8_K28_E0.9581.00
11_M28_E0.9531.00
35_G124_S0.9451.00
71_L103_V0.9360.99
50_F144_F0.9270.99
74_L135_I0.9250.99
19_F94_P0.9240.99
4_G80_T0.9160.99
68_Q84_T0.9120.99
89_M97_L0.9040.99
63_P116_T0.9020.99
34_F37_A0.8900.99
88_Y110_L0.8850.99
19_F116_T0.8850.99
70_V144_F0.8760.99
109_V114_P0.8730.99
84_T142_I0.8640.99
7_V97_L0.8430.99
5_V97_L0.8370.99
3_D79_K0.8310.99
71_L99_I0.8230.99
7_V85_D0.8140.99
30_L101_K0.8120.99
12_K21_A0.8040.98
3_D80_T0.8040.98
20_F38_S0.8030.98
39_W63_P0.8010.98
43_Y114_P0.7960.98
118_I121_T0.7890.98
8_K59_L0.7780.98
98_L122_T0.7600.98
86_V147_N0.7580.98
43_Y113_T0.7580.98
110_L147_N0.7550.98
80_T83_E0.7520.98
62_F115_L0.7480.98
34_F122_T0.7470.97
55_K126_N0.7430.97
30_L98_L0.7380.97
71_L97_L0.7320.97
23_L39_W0.7250.97
7_V93_N0.7220.97
26_D31_L0.7200.97
14_S94_P0.7190.97
66_H115_L0.7170.97
58_D69_V0.7160.97
32_E122_T0.7110.97
62_F67_A0.7050.96
52_Y135_I0.6990.96
21_A94_P0.6910.96
30_L33_H0.6910.96
61_F118_I0.6890.96
91_E94_P0.6860.96
85_D97_L0.6840.96
23_L61_F0.6840.96
42_S48_K0.6800.96
43_Y46_V0.6790.96
22_E38_S0.6760.96
94_P116_T0.6720.95
50_F142_I0.6690.95
42_S46_V0.6670.95
12_K19_F0.6620.95
47_I146_W0.6600.95
23_L118_I0.6520.95
125_Y132_E0.6500.94
15_D18_G0.6490.94
47_I137_W0.6480.94
20_F119_Y0.6380.94
68_Q110_L0.6310.94
72_Y104_A0.6300.93
76_E79_K0.6270.93
11_M14_S0.6230.93
56_Q121_T0.6170.93
35_G123_M0.6160.93
38_S119_Y0.6160.93
50_F135_I0.6140.93
3_D6_K0.6120.92
34_F120_F0.6110.92
41_K64_T0.6090.92
67_A107_Y0.6070.92
14_S43_Y0.6070.92
70_V86_V0.6040.92
123_M131_D0.6030.92
90_G94_P0.5970.92
91_E116_T0.5960.91
23_L120_F0.5950.91
60_W117_I0.5950.91
9_K93_N0.5940.91
66_H110_L0.5910.91
6_K100_P0.5900.91
59_L98_L0.5890.91
142_I145_N0.5870.91
61_F116_T0.5870.91
72_Y135_I0.5860.91
59_L96_L0.5820.91
26_D124_S0.5800.90
98_L101_K0.5760.90
5_V103_V0.5740.90
10_L96_L0.5720.90
88_Y147_N0.5710.90
88_Y93_N0.5710.90
72_Y142_I0.5700.90
91_E111_G0.5660.89
85_D88_Y0.5640.89
68_Q88_Y0.5630.89
76_E82_G0.5620.89
60_W69_V0.5590.89
121_T133_K0.5580.89
55_K123_M0.5560.88
8_K30_L0.5550.88
67_A109_V0.5540.88
10_L21_A0.5510.88
71_L87_Y0.5490.88
73_D80_T0.5450.87
68_Q145_N0.5430.87
20_F36_Q0.5420.87
105_H132_E0.5420.87
6_K29_N0.5420.87
56_Q105_H0.5400.87
6_K98_L0.5400.87
140_E143_G0.5380.87
21_A39_W0.5370.87
59_L142_I0.5360.87
26_D145_N0.5350.86
106_G146_W0.5340.86
29_N32_E0.5300.86
66_H91_E0.5290.86
44_P109_V0.5230.85
20_F121_T0.5230.85
75_R102_G0.5220.85
47_I147_N0.5180.85
47_I148_T0.5140.84
21_A61_F0.5130.84
61_F96_L0.5120.84
69_V97_L0.5090.84
53_H132_E0.5070.83
60_W67_A0.5060.83
89_M95_M0.5040.83
32_E57_D0.5000.83
62_F117_I0.5000.83
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4hn1A 3 0.9801 100 0.146 Contact Map
2c0zA 2 0.9735 100 0.146 Contact Map
1upiA 2 0.9801 100 0.147 Contact Map
1oi6A 2 0.9801 100 0.15 Contact Map
2ixkA 2 0.9801 100 0.151 Contact Map
1dzrA 2 0.9801 100 0.155 Contact Map
3rykA 2 0.9801 100 0.156 Contact Map
1ep0A 2 0.9801 100 0.159 Contact Map
1nxmA 2 0.9536 100 0.2 Contact Map
5buvA 2 0.9669 100 0.21 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0066 seconds.