GREMLIN Database
YERC - Uncharacterized protein YerC
UniProt: Q7BVT7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 104 (93)
Sequences: 636 (394)
Seq/√Len: 40.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
16_N24_L6.5191.00
18_I31_F3.2161.00
15_F31_F2.9521.00
54_R88_E2.9121.00
35_C43_L2.5921.00
79_C91_L2.2991.00
12_D28_Y2.1250.99
14_L34_L2.0870.99
27_C31_F2.0830.99
19_L27_C1.9440.99
26_E93_R1.9210.99
58_T63_E1.8990.99
13_Q48_E1.8740.98
63_E70_T1.7960.98
8_G11_L1.7350.97
13_Q51_R1.7140.97
20_S90_A1.7120.97
49_V68_A1.6980.97
15_F27_C1.6660.97
22_K93_R1.6280.96
15_F18_I1.3890.91
55_E95_K1.3750.91
60_H77_K1.3290.89
45_Q68_A1.3190.89
60_H63_E1.3070.88
26_E89_M1.2690.87
16_N20_S1.2390.85
32_D82_Y1.1950.83
34_L43_L1.1870.83
9_K65_E1.1610.81
54_R95_K1.1580.81
61_K65_E1.1550.81
17_S47_L1.1540.81
11_L60_H1.1520.81
13_Q47_L1.1470.81
88_E92_D1.1460.80
10_E38_N1.0890.77
38_N43_L1.0830.77
37_I82_Y1.0630.75
10_E48_E1.0570.75
17_S30_F1.0350.73
57_N65_E1.0340.73
9_K97_T1.0160.72
29_R89_M0.9990.71
89_M93_R0.9990.71
21_L30_F0.9910.70
32_D84_N0.9850.69
18_I27_C0.9720.68
74_S78_R0.9690.68
36_T86_A0.9640.68
11_L48_E0.9520.67
45_Q49_V0.9480.66
20_S24_L0.9370.66
16_N97_T0.9340.65
37_I80_L0.9230.64
79_C84_N0.9090.63
26_E30_F0.9080.63
40_I79_C0.9000.62
68_A76_V0.8940.62
54_R80_L0.8810.61
68_A74_S0.8510.58
40_I61_K0.8440.57
50_A70_T0.8410.57
51_R55_E0.8170.55
20_S94_V0.8160.55
45_Q74_S0.8120.54
35_C71_A0.7890.52
7_R11_L0.7840.52
14_L61_K0.7760.51
8_G32_D0.7730.51
10_E44_A0.7680.50
48_E65_E0.7560.49
21_L27_C0.7560.49
36_T87_Y0.7450.48
6_L78_R0.7440.48
76_V80_L0.7430.48
45_Q50_A0.7350.47
16_N25_E0.7270.47
34_L37_I0.7260.46
29_R85_D0.7250.46
38_N61_K0.7070.45
57_N61_K0.7060.45
35_C40_I0.7050.45
22_K97_T0.7000.44
19_L22_K0.6960.44
47_L50_A0.6870.43
63_E76_V0.6780.42
17_S20_S0.6630.41
89_M92_D0.6590.40
13_Q52_M0.6550.40
55_E96_E0.6520.40
69_S72_T0.6460.39
37_I71_A0.6450.39
41_Q47_L0.6430.39
17_S89_M0.6430.39
44_A94_V0.6360.38
63_E77_K0.6340.38
17_S90_A0.6260.37
49_V81_N0.6260.37
11_L44_A0.6160.37
18_I93_R0.6110.36
66_T71_A0.6110.36
47_L51_R0.6050.36
13_Q16_N0.5970.35
20_S23_D0.5920.35
8_G77_K0.5910.34
71_A74_S0.5840.34
9_K13_Q0.5830.34
76_V85_D0.5830.34
44_A58_T0.5710.33
42_S68_A0.5710.33
47_L77_K0.5700.33
77_K81_N0.5680.33
72_T87_Y0.5610.32
45_Q83_G0.5560.32
47_L94_V0.5470.31
50_A74_S0.5420.31
25_E34_L0.5410.30
79_C88_E0.5400.30
20_S54_R0.5330.30
43_L76_V0.5310.30
13_Q77_K0.5300.30
29_R79_C0.5260.29
32_D79_C0.5260.29
84_N91_L0.5240.29
34_L90_A0.5210.29
14_L35_C0.5190.29
22_K88_E0.5140.28
34_L81_N0.5140.28
34_L60_H0.5140.28
56_G62_I0.5120.28
64_T78_R0.5120.28
79_C87_Y0.5120.28
20_S97_T0.5100.28
40_I44_A0.5100.28
18_I30_F0.5080.28
49_V66_T0.5070.28
15_F44_A0.5040.28
50_A63_E0.5040.28
38_N58_T0.5000.27
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3frwA 2 0.9423 99.9 0.407 Contact Map
3korA 2 0.9519 99.4 0.674 Contact Map
1jhgA 2 0.9519 98.8 0.747 Contact Map
1tc3C 1 0.4808 94.8 0.863 Contact Map
1u78A 1 0.6538 92 0.876 Contact Map
3iwfA 2 0.7212 91.3 0.879 Contact Map
4ivnA 2 0.6731 91.1 0.879 Contact Map
2m8eA 1 0.5481 90.8 0.88 Contact Map
1u2wA 2 0.8462 89.2 0.884 Contact Map
4fcyA 4 0.6923 88.7 0.885 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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