YFNA - BACSU - GREMLIN Contacts

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YFNA - Uncharacterized amino acid permease YfnA

UniProt:	Q797A7	Sequences: MSSLFRKKPLETLSAQSKSKSLARTLSAFDLTLLGIGCVIGTGIFVITGTVAATGAGPALIISFILAGLACALAAFCYAEFSSSIPISGSVYSYSYVTLGELLAFLIGWDLMLEYVIALSAVATGWSSYFQSLLAGFNLHIPAALTGAPGSMAGAVFNLPAAVIILLITAIVSRGVKESTRFNNVIVLMKIAIILLFIIVGIGYVKPDNWSPFMPFGMKGVILSAATVFFAYLGFDAVSNASEEVKNPQKNMPVGIISALAVCTVLYIAVSLVLTGMMPYAKLNVGDPVSFALKFVGQDAVAGIISVGAIIGITTVMLALLYAQVRLTFAMSRDGLLPGLFAKVHPSFKTPFRNTWLTGIVAAGIAGFINLGTLAHLVNMGTLAAFTVISIAVIVLRKKHPEIKASFRVPFVPVVPIISAGICLWFMYSLPGVTWLSFVIWIAVGTLVYFLYSRKHSLLNK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	461 (413)
Sequences:	24577 (15666)
Seq/√Len:	770.9

ECOLI - PUUP FRLA PLAP CYCA POTE ANSP PROY AROP PHEP MMUP GABP LYSP ADIC YBAT YIFK YCAM YGJI GADC YJEM CADB ARCD YJEH
BACSU - YFNA YHDG ASPP YBEC STET YDGF YTNA YBGF HUTM AAPA ROCC ARCD GABP YBXG ROCE YECA YVBW YCGH YDAO GERBB GERAB YNDE GERKB
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97XM0 Q97X49 Q97U05 Q97WS3 Q97VA6 Q97Z63 Q97U33 Q97ZB5 Q97VA8 Q7LXI7 Q97VR4 Q97WD4 Q97YN3 Q97Y76 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
169_T	359_G	4.365	1.00
340_L	353_R	4.265	1.00
68_G	264_T	3.198	1.00
395_V	399_K	3.032	1.00
343_K	353_R	3.031	1.00
250_K	254_V	3.018	1.00
27_S	246_K	2.848	1.00
345_H	348_F	2.781	1.00
92_Y	334_D	2.779	1.00
387_T	420_A	2.746	1.00
245_V	251_N	2.744	1.00
108_G	331_M	2.665	1.00
247_N	250_K	2.592	1.00
332_S	342_A	2.552	1.00
201_G	273_V	2.533	1.00
345_H	352_F	2.500	1.00
162_A	363_A	2.475	1.00
32_T	258_S	2.463	1.00
340_L	343_K	2.441	1.00
80_E	397_R	2.423	1.00
243_E	333_R	2.422	1.00
28_A	258_S	2.406	1.00
300_A	304_I	2.384	1.00
199_I	203_G	2.251	1.00
96_Y	104_A	2.248	1.00
356_W	360_I	2.204	1.00
28_A	251_N	2.182	1.00
329_F	333_R	2.150	1.00
244_E	326_R	2.145	1.00
28_A	32_T	2.132	1.00
170_A	174_R	2.130	1.00
169_T	355_T	2.102	1.00
31_L	245_V	2.097	1.00
166_L	363_A	2.095	1.00
417_I	421_G	2.089	1.00
161_A	366_A	2.056	1.00
51_V	60_L	2.026	1.00
177_K	181_R	2.009	1.00
173_S	352_F	2.008	1.00
412_V	416_P	1.986	1.00
77_C	390_S	1.973	1.00
390_S	419_S	1.963	1.00
254_V	258_S	1.962	1.00
96_Y	101_E	1.952	1.00
22_L	344_V	1.949	1.00
112_M	358_T	1.944	1.00
188_L	192_A	1.939	1.00
99_L	395_V	1.937	1.00
27_S	30_D	1.930	1.00
162_A	366_A	1.922	1.00
335_G	339_G	1.902	1.00
341_F	357_L	1.879	1.00
69_L	73_L	1.845	1.00
99_L	391_I	1.825	1.00
447_L	451_L	1.814	1.00
279_P	282_K	1.799	1.00
291_F	294_K	1.779	1.00
421_G	425_W	1.774	1.00
30_D	184_N	1.761	1.00
257_I	261_A	1.757	1.00
123_A	317_M	1.734	1.00
63_S	224_S	1.729	1.00
166_L	359_G	1.717	1.00
172_V	318_L	1.717	1.00
95_S	107_I	1.704	1.00
247_N	251_N	1.701	1.00
282_K	295_F	1.679	1.00
107_I	388_V	1.673	1.00
411_F	415_V	1.663	1.00
285_V	291_F	1.655	1.00
441_W	445_G	1.654	1.00
59_A	221_V	1.650	1.00
35_G	259_A	1.638	1.00
212_P	215_P	1.634	1.00
173_S	356_W	1.618	1.00
119_L	362_A	1.610	1.00
32_T	262_V	1.608	1.00
100_G	103_L	1.596	1.00
165_I	362_A	1.586	1.00
192_A	196_L	1.576	1.00
26_L	30_D	1.572	1.00
130_F	160_P	1.553	1.00
241_A	322_Y	1.538	1.00
395_V	398_K	1.527	1.00
425_W	429_S	1.514	1.00
345_H	350_T	1.481	1.00
109_W	445_G	1.473	1.00
193_I	308_G	1.468	1.00
439_V	443_A	1.467	1.00
414_V	418_I	1.465	1.00
67_A	228_V	1.465	1.00
247_N	254_V	1.460	1.00
261_A	265_V	1.454	1.00
353_R	357_L	1.445	1.00
328_T	354_N	1.435	1.00
191_I	195_L	1.434	1.00
126_W	310_I	1.418	1.00
174_R	348_F	1.417	1.00
287_D	291_F	1.415	1.00
75_A	260_L	1.411	1.00
329_F	344_V	1.407	1.00
169_T	356_W	1.400	1.00
123_A	165_I	1.399	1.00
324_Q	358_T	1.398	1.00
23_A	349_K	1.397	1.00
339_G	343_K	1.396	1.00
162_A	166_L	1.393	1.00
348_F	352_F	1.391	1.00
391_I	395_V	1.384	1.00
30_D	180_T	1.383	1.00
285_V	288_P	1.381	1.00
400_H	403_I	1.378	1.00
22_L	329_F	1.376	1.00
69_L	418_I	1.368	1.00
325_V	355_T	1.366	1.00
95_S	388_V	1.365	1.00
401_P	405_A	1.363	1.00
165_I	359_G	1.362	1.00
88_S	243_E	1.360	1.00
294_K	302_A	1.357	1.00
339_G	342_A	1.356	1.00
126_W	164_I	1.345	1.00
248_P	253_P	1.324	1.00
202_I	273_V	1.324	1.00
99_L	103_L	1.320	1.00
303_G	307_V	1.300	1.00
251_N	254_V	1.297	1.00
445_G	448_V	1.292	1.00
26_L	31_L	1.288	1.00
343_K	352_F	1.282	1.00
26_L	180_T	1.280	1.00
168_I	317_M	1.276	1.00
85_I	97_V	1.273	1.00
413_P	417_I	1.272	1.00
46_V	125_G	1.271	1.00
39_V	263_C	1.271	1.00
75_A	256_I	1.267	1.00
446_T	450_F	1.266	1.00
205_V	276_G	1.262	1.00
73_L	418_I	1.255	1.00
70_A	422_I	1.255	1.00
74_A	390_S	1.254	1.00
28_A	254_V	1.252	1.00
87_I	93_S	1.251	1.00
291_F	295_F	1.249	1.00
265_V	269_A	1.248	1.00
98_T	392_A	1.240	1.00
76_F	257_I	1.240	1.00
59_A	214_M	1.236	1.00
93_S	97_V	1.236	1.00
198_I	269_A	1.229	1.00
391_I	420_A	1.224	1.00
84_S	405_A	1.222	1.00
122_V	316_V	1.220	1.00
328_T	337_L	1.212	1.00
29_F	33_L	1.207	1.00
171_I	182_F	1.206	1.00
61_I	272_L	1.205	1.00
87_I	97_V	1.202	1.00
201_G	277_M	1.200	1.00
416_P	420_A	1.199	1.00
102_L	452_Y	1.195	1.00
280_Y	283_L	1.187	1.00
197_F	201_G	1.186	1.00
411_F	414_V	1.170	1.00
440_I	444_V	1.168	1.00
158_N	162_A	1.160	1.00
203_G	208_D	1.159	1.00
424_L	428_Y	1.155	1.00
77_C	416_P	1.154	1.00
78_Y	91_V	1.142	1.00
435_W	438_F	1.138	1.00
112_M	328_T	1.135	1.00
105_F	109_W	1.131	1.00
419_S	423_C	1.128	1.00
413_P	416_P	1.121	1.00
183_N	318_L	1.114	1.00
436_L	440_I	1.107	1.00
92_Y	330_A	1.106	1.00
423_C	426_F	1.103	1.00
31_L	255_G	1.101	1.00
36_I	262_V	1.098	1.00
246_K	251_N	1.098	1.00
159_L	163_V	1.095	1.00
95_S	103_L	1.094	1.00
433_V	436_L	1.092	1.00
82_S	94_Y	1.085	1.00
353_R	356_W	1.078	1.00
52_A	60_L	1.075	1.00
411_F	416_P	1.070	1.00
205_V	208_D	1.063	1.00
196_L	200_V	1.063	1.00
156_V	159_L	1.057	1.00
25_T	246_K	1.055	1.00
428_Y	432_G	1.055	1.00
35_G	238_V	1.053	1.00
344_V	349_K	1.048	1.00
181_R	185_V	1.047	1.00
163_V	167_L	1.045	1.00
434_T	438_F	1.038	1.00
84_S	403_I	1.037	1.00
420_A	424_L	1.036	1.00
298_Q	301_V	1.036	1.00
416_P	423_C	1.036	1.00
182_F	186_I	1.030	1.00
34_L	241_A	1.029	1.00
433_V	437_S	1.029	1.00
202_I	206_K	1.028	1.00
203_G	207_P	1.027	1.00
360_I	364_G	1.020	1.00
127_S	160_P	1.020	1.00
80_E	83_S	1.017	1.00
36_I	263_C	1.017	1.00
436_L	439_V	1.015	1.00
169_T	173_S	1.007	1.00
333_R	342_A	1.006	1.00
448_V	451_L	1.001	1.00
173_S	350_T	1.001	1.00
102_L	446_T	0.999	1.00
97_V	400_H	0.998	1.00
294_K	299_D	0.996	1.00
166_L	170_A	0.992	1.00
387_T	424_L	0.988	1.00
416_P	429_S	0.986	1.00
130_F	310_I	0.985	1.00
343_K	346_P	0.985	1.00
437_S	440_I	0.982	1.00
195_L	199_I	0.972	1.00
414_V	417_I	0.969	1.00
440_I	443_A	0.969	1.00
191_I	266_L	0.968	1.00
443_A	447_L	0.967	1.00
394_I	417_I	0.966	1.00
448_V	452_Y	0.963	1.00
428_Y	431_P	0.963	1.00
176_V	322_Y	0.962	1.00
435_W	439_V	0.958	1.00
297_G	301_V	0.955	1.00
399_K	403_I	0.952	1.00
425_W	430_L	0.952	1.00
186_I	315_T	0.951	1.00
387_T	391_I	0.948	1.00
419_S	422_I	0.948	1.00
422_I	425_W	0.946	1.00
425_W	428_Y	0.942	1.00
167_L	314_T	0.941	1.00
233_L	382_T	0.939	1.00
289_V	293_L	0.934	1.00
203_G	206_K	0.929	1.00
423_C	427_M	0.927	1.00
65_I	268_I	0.926	1.00
198_I	273_V	0.925	1.00
236_D	240_N	0.921	1.00
242_S	252_M	0.917	1.00
402_E	405_A	0.913	1.00
130_F	134_L	0.913	1.00
258_S	262_V	0.906	1.00
426_F	430_L	0.903	1.00
399_K	402_E	0.901	1.00
380_M	438_F	0.900	1.00
403_I	406_S	0.898	1.00
444_V	447_L	0.897	1.00
352_F	356_W	0.896	1.00
416_P	419_S	0.895	1.00
68_G	232_Y	0.892	1.00
321_L	359_G	0.891	1.00
121_A	230_F	0.891	1.00
210_W	215_P	0.889	1.00
109_W	337_L	0.886	1.00
416_P	422_I	0.886	1.00
299_D	303_G	0.885	1.00
30_D	181_R	0.883	1.00
61_I	275_T	0.882	1.00
415_V	419_S	0.879	1.00
393_V	416_P	0.878	1.00
121_A	375_A	0.878	1.00
22_L	244_E	0.877	1.00
127_S	161_A	0.877	1.00
407_F	410_P	0.874	1.00
412_V	415_V	0.874	1.00
83_S	406_S	0.868	1.00
89_G	92_Y	0.866	1.00
33_L	184_N	0.864	1.00
160_P	163_V	0.863	1.00
168_I	318_L	0.862	1.00
209_N	212_P	0.862	1.00
96_Y	334_D	0.859	1.00
89_G	93_S	0.859	1.00
441_W	448_V	0.858	1.00
419_S	430_L	0.855	1.00
264_T	268_I	0.854	1.00
25_T	177_K	0.851	1.00
272_L	276_G	0.851	1.00
102_L	106_L	0.850	1.00
197_F	293_L	0.850	1.00
198_I	202_I	0.850	1.00
223_L	227_T	0.849	1.00
404_K	408_R	0.842	1.00
214_M	221_V	0.841	1.00
22_L	326_R	0.838	1.00
126_W	313_I	0.828	1.00
127_S	157_F	0.828	1.00
168_I	321_L	0.827	1.00
438_F	442_I	0.826	1.00
217_G	220_G	0.826	1.00
29_F	184_N	0.826	1.00
40_I	43_G	0.822	1.00
84_S	406_S	0.822	1.00
341_F	353_R	0.820	1.00
170_A	173_S	0.820	1.00
377_L	381_G	0.819	1.00
126_W	314_T	0.815	1.00
190_K	312_G	0.815	1.00
72_A	76_F	0.814	1.00
425_W	432_G	0.811	1.00
81_F	393_V	0.811	1.00
28_A	255_G	0.809	1.00
72_A	257_I	0.808	1.00
62_I	221_V	0.806	1.00
237_A	323_A	0.804	1.00
222_I	425_W	0.798	1.00
65_I	69_L	0.797	1.00
434_T	437_S	0.796	1.00
359_G	363_A	0.795	1.00
422_I	429_S	0.794	1.00
103_L	388_V	0.794	1.00
415_V	429_S	0.793	1.00
202_I	269_A	0.792	1.00
416_P	430_L	0.788	1.00
288_P	292_A	0.788	1.00
287_D	290_S	0.786	1.00
173_S	345_H	0.782	1.00
337_L	341_F	0.782	1.00
233_L	386_F	0.780	1.00
95_S	392_A	0.778	1.00
172_V	355_T	0.777	1.00
73_L	77_C	0.777	1.00
288_P	291_F	0.775	1.00
181_R	184_N	0.774	1.00
416_P	432_G	0.774	1.00
165_I	366_A	0.771	1.00
247_N	253_P	0.768	1.00
279_P	295_F	0.763	1.00
444_V	448_V	0.760	1.00
73_L	415_V	0.757	1.00
398_K	413_P	0.754	1.00
394_I	398_K	0.754	1.00
429_S	432_G	0.753	1.00
158_N	366_A	0.751	1.00
284_N	287_D	0.750	1.00
394_I	416_P	0.749	1.00
210_W	275_T	0.748	1.00
412_V	417_I	0.747	1.00
32_T	255_G	0.746	1.00
131_Q	157_F	0.744	1.00
445_G	449_Y	0.742	1.00
413_P	430_L	0.737	1.00
209_N	215_P	0.736	1.00
57_G	275_T	0.735	1.00
210_W	276_G	0.731	1.00
441_W	444_V	0.731	1.00
321_L	325_V	0.729	1.00
346_P	352_F	0.727	1.00
44_I	270_V	0.726	1.00
174_R	178_E	0.726	1.00
447_L	450_F	0.726	1.00
40_I	190_K	0.722	1.00
98_T	395_V	0.721	1.00
419_S	429_S	0.720	1.00
180_T	184_N	0.720	1.00
173_S	348_F	0.720	1.00
39_V	259_A	0.720	1.00
418_I	421_G	0.720	1.00
412_V	429_S	0.718	1.00
81_F	94_Y	0.718	1.00
393_V	397_R	0.715	1.00
284_N	291_F	0.713	1.00
62_I	65_I	0.712	1.00
258_S	261_A	0.712	1.00
124_T	374_L	0.710	1.00
205_V	273_V	0.707	1.00
392_A	396_L	0.707	1.00
120_S	374_L	0.707	1.00
62_I	66_L	0.705	1.00
405_A	408_R	0.702	1.00
84_S	401_P	0.702	1.00
66_L	225_A	0.700	1.00
118_A	122_V	0.697	1.00
449_Y	452_Y	0.697	1.00
162_A	367_G	0.697	1.00
381_G	385_A	0.696	1.00
284_N	288_P	0.695	1.00
37_G	187_V	0.694	1.00
277_M	292_A	0.692	1.00
253_P	256_I	0.691	1.00
218_M	221_V	0.687	1.00
325_V	354_N	0.687	1.00
172_V	322_Y	0.687	1.00
120_S	365_I	0.685	1.00
25_T	176_V	0.684	1.00
418_I	429_S	0.680	1.00
111_L	115_Y	0.679	1.00
61_I	65_I	0.677	1.00
29_F	181_R	0.676	1.00
390_S	420_A	0.676	1.00
78_Y	389_I	0.676	1.00
417_I	420_A	0.676	1.00
442_I	446_T	0.676	1.00
114_E	382_T	0.672	1.00
345_H	349_K	0.672	1.00
168_I	314_T	0.671	1.00
127_S	130_F	0.670	1.00
427_M	430_L	0.669	1.00
92_Y	96_Y	0.667	1.00
360_I	363_A	0.664	1.00
116_V	361_V	0.662	1.00
341_F	354_N	0.662	1.00
118_A	378_V	0.662	1.00
332_S	341_F	0.662	1.00
422_I	426_F	0.661	1.00
326_R	329_F	0.660	1.00
129_Y	309_A	0.659	1.00
351_P	354_N	0.658	1.00
164_I	317_M	0.657	1.00
262_V	266_L	0.657	1.00
180_T	318_L	0.655	1.00
423_C	430_L	0.653	1.00
220_G	223_L	0.653	1.00
328_T	357_L	0.652	1.00
433_V	438_F	0.651	1.00
439_V	442_I	0.650	1.00
40_I	45_F	0.650	1.00
178_E	181_R	0.649	1.00
110_D	385_A	0.649	1.00
243_E	329_F	0.648	1.00
100_G	104_A	0.648	1.00
71_C	235_F	0.648	1.00
239_S	256_I	0.646	1.00
204_Y	207_P	0.644	1.00
412_V	419_S	0.641	1.00
269_A	273_V	0.640	1.00
118_A	121_A	0.640	1.00
166_L	169_T	0.640	1.00
32_T	35_G	0.639	1.00
130_F	164_I	0.639	1.00
200_V	298_Q	0.639	1.00
98_T	396_L	0.638	1.00
58_P	213_F	0.636	1.00
22_L	25_T	0.634	1.00
25_T	29_F	0.633	1.00
300_A	303_G	0.633	1.00
218_M	222_I	0.633	1.00
346_P	349_K	0.632	1.00
173_S	355_T	0.631	1.00
82_S	239_S	0.630	1.00
340_L	357_L	0.628	1.00
244_E	351_P	0.626	1.00
75_A	235_F	0.623	1.00
198_I	270_V	0.623	1.00
176_V	241_A	0.621	1.00
200_V	204_Y	0.621	1.00
88_S	329_F	0.621	1.00
44_I	48_T	0.621	1.00
158_N	161_A	0.620	1.00
80_E	408_R	0.618	1.00
249_Q	404_K	0.617	1.00
270_V	274_L	0.615	1.00
132_S	306_S	0.614	1.00
38_C	319_A	0.614	1.00
413_P	429_S	0.611	1.00
245_V	252_M	0.611	1.00
79_A	83_S	0.610	1.00
435_W	442_I	0.610	1.00
82_S	252_M	0.607	1.00
262_V	265_V	0.607	1.00
175_G	178_E	0.604	1.00
77_C	419_S	0.603	1.00
387_T	423_C	0.602	1.00
252_M	256_I	0.600	1.00
122_V	317_M	0.598	1.00
434_T	441_W	0.597	1.00
415_V	430_L	0.597	1.00
51_V	228_V	0.596	1.00
426_F	429_S	0.596	1.00
205_V	277_M	0.594	1.00
370_N	373_T	0.593	1.00
92_Y	104_A	0.593	1.00
91_V	240_N	0.593	1.00
64_F	231_A	0.593	1.00
91_V	236_D	0.592	1.00
420_A	423_C	0.592	1.00
41_G	267_Y	0.591	1.00
117_I	377_L	0.590	1.00
340_L	344_V	0.589	1.00
59_A	213_F	0.589	1.00
411_F	430_L	0.589	1.00
416_P	431_P	0.588	1.00
80_E	410_P	0.588	1.00
92_Y	108_G	0.586	1.00
233_L	236_D	0.586	1.00
60_L	271_S	0.585	1.00
38_C	320_L	0.585	1.00
115_Y	320_L	0.585	1.00
35_G	39_V	0.585	1.00
312_G	315_T	0.583	1.00
74_A	423_C	0.583	1.00
273_V	276_G	0.582	1.00
120_S	362_A	0.580	1.00
394_I	413_P	0.580	1.00
56_A	59_A	0.579	1.00
216_F	219_K	0.579	1.00
371_L	375_A	0.577	1.00
438_F	443_A	0.575	1.00
442_I	445_G	0.574	1.00
189_M	308_G	0.574	1.00
38_C	237_A	0.574	1.00
47_I	375_A	0.573	1.00
51_V	55_G	0.572	1.00
169_T	321_L	0.570	1.00
416_P	428_Y	0.570	1.00
397_R	401_P	0.570	1.00
307_V	311_I	0.566	1.00
443_A	446_T	0.566	1.00
326_R	351_P	0.566	1.00
116_V	358_T	0.565	1.00
55_G	224_S	0.563	1.00
324_Q	328_T	0.563	1.00
167_L	171_I	0.563	1.00
75_A	79_A	0.563	1.00
420_A	431_P	0.562	1.00
134_L	137_F	0.561	1.00
420_A	430_L	0.560	1.00
133_L	307_V	0.560	1.00
441_W	446_T	0.560	1.00
435_W	448_V	0.559	1.00
270_V	289_V	0.557	1.00
99_L	392_A	0.557	1.00
50_T	372_G	0.556	1.00
40_I	266_L	0.556	1.00
222_I	429_S	0.556	1.00
102_L	449_Y	0.556	1.00
446_T	449_Y	0.556	1.00
262_V	269_A	0.554	1.00
80_E	407_F	0.554	1.00
250_K	253_P	0.553	1.00
214_M	218_M	0.552	1.00
178_E	182_F	0.552	1.00
209_N	276_G	0.552	1.00
122_V	125_G	0.551	1.00
210_W	213_F	0.551	1.00
133_L	306_S	0.550	1.00
61_I	268_I	0.549	1.00
41_G	45_F	0.549	1.00
421_G	424_L	0.549	1.00
48_T	271_S	0.548	1.00
418_I	422_I	0.548	1.00
240_N	323_A	0.547	1.00
184_N	188_L	0.546	1.00
406_S	410_P	0.546	1.00
125_G	129_Y	0.546	1.00
179_S	322_Y	0.544	1.00
44_I	194_I	0.544	1.00
249_Q	406_S	0.544	1.00
165_I	363_A	0.544	1.00
36_I	187_V	0.543	1.00
435_W	440_I	0.539	1.00
48_T	51_V	0.539	1.00
74_A	236_D	0.538	1.00
22_L	88_S	0.538	1.00
440_I	447_L	0.537	1.00
412_V	422_I	0.537	1.00
95_S	104_A	0.535	1.00
110_D	384_A	0.535	1.00
422_I	430_L	0.534	1.00
401_P	404_K	0.534	1.00
189_M	193_I	0.534	1.00
164_I	168_I	0.533	1.00
192_A	195_L	0.532	1.00
67_A	229_F	0.530	1.00
123_A	168_I	0.530	1.00
29_F	32_T	0.530	1.00
185_V	188_L	0.529	1.00
396_L	405_A	0.529	1.00
27_S	177_K	0.529	1.00
114_E	381_G	0.528	1.00
45_F	194_I	0.527	1.00
183_N	315_T	0.527	1.00
80_E	84_S	0.526	1.00
189_M	311_I	0.526	1.00
402_E	408_R	0.525	1.00
372_G	375_A	0.524	1.00
185_V	189_M	0.523	1.00
427_M	435_W	0.521	1.00
183_N	190_K	0.521	1.00
67_A	232_Y	0.520	1.00
236_D	386_F	0.520	1.00
209_N	214_M	0.520	1.00
36_I	39_V	0.518	1.00
164_I	314_T	0.517	1.00
61_I	64_F	0.514	1.00
326_R	344_V	0.513	1.00
436_L	441_W	0.512	1.00
438_F	441_W	0.512	1.00
416_P	427_M	0.512	1.00
81_F	98_T	0.511	1.00
116_V	365_I	0.511	1.00
405_A	409_V	0.511	1.00
245_V	255_G	0.510	1.00
437_S	441_W	0.510	1.00
79_A	256_I	0.509	1.00
382_T	385_A	0.508	1.00
248_P	251_N	0.508	1.00
123_A	127_S	0.507	1.00
412_V	420_A	0.507	1.00
133_L	310_I	0.505	1.00
120_S	123_A	0.503	1.00
278_M	282_K	0.503	1.00
352_F	355_T	0.502	1.00
193_I	304_I	0.502	1.00
357_L	361_V	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.8894	100	0.326	Contact Map
3giaA	1	0.9067	100	0.369	Contact Map
4djkA	2	0.8785	100	0.389	Contact Map
2jlnA	1	0.8872	99	0.854	Contact Map
3dh4A	3	0.872	98.6	0.873	Contact Map
2xq2A	2	0.885	98.3	0.885	Contact Map
4xp4A	1	0.9241	98.1	0.892	Contact Map
2a65A	2	0.9089	98	0.894	Contact Map
4wgvA	2	0.7766	97.6	0.903	Contact Map
4us3A	1	0.8612	97.4	0.906	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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