YGAK - BACSU - GREMLIN Contacts

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YGAK - Uncharacterized FAD-linked oxidoreductase YgaK

UniProt:	Q796Y5	Sequences: MEKTKLTGRIVTRDDPDYNEARTNINLSLERYPDIIVFCQNKQDALNALKWARENRVPFRIRGGRHSYENFSLLNNGLVIDLSEMKKITVNQDKKLAYIEAGAELGEVYRTLWQYGLTLPAGTIANVGLTGLTLGGGIGLLTRAAGLTCDSLVQLEMIVADEKEGADLITVSCSNHPDLFWASQGGGGGNFGIVTSMTFKAVPISQVSIFSITWGWDDFEEVYNTWQNWAPYTDDRLTSSIEFWPKEVNRIEALGQFVGPKTELKKLLKPLLKAGSPTSGMVKTTPFIEAVTFFNSPGGNQPQKMKRSGSFIEKPLSERAISTIKHFLEHAPNQNASVWQQALGGAAGRVAPDQTAFYYRDAIIAQEYLTNWTSPGEKRQNVRWIEGLRTSLSKETMGDYVNWPDIEIRNWPRTYYGENVERLRRVKTTYDPENVFRFEQSIPPLRRSLFF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	451 (410)
Sequences:	18620 (14045)
Seq/√Len:	693.6

ECOLI - GLCD YGCU YDIJ GLCE
BACSU - YGAK YVDP GLCD YITY
HALSA - Q9HMR2
SULSO - Q97U60 Q97Y18 Q7LX43 Q97U59 Q97ZB9 Q7LXI5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
161_D	167_D	4.805	1.00
156_E	196_S	4.059	1.00
42_K	156_E	3.931	1.00
53_R	433_E	3.791	1.00
133_T	197_M	3.458	1.00
87_K	100_E	3.310	1.00
153_V	200_K	3.186	1.00
56_R	433_E	3.051	1.00
91_N	94_K	3.021	1.00
86_K	107_E	2.967	1.00
98_Y	196_S	2.868	1.00
156_E	170_T	2.867	1.00
111_T	114_Q	2.830	1.00
98_Y	198_T	2.807	1.00
117_L	201_A	2.716	1.00
37_V	48_A	2.692	1.00
157_M	183_S	2.672	1.00
45_A	195_T	2.498	1.00
218_D	221_E	2.488	1.00
46_L	168_L	2.409	1.00
100_E	196_S	2.398	1.00
40_Q	84_E	2.348	1.00
49_L	59_F	2.300	1.00
154_Q	170_T	2.292	1.00
92_Q	115_Y	2.291	1.00
159_V	167_D	2.284	1.00
103_A	108_V	2.272	1.00
154_Q	198_T	2.248	1.00
335_N	338_V	2.199	1.00
160_A	436_F	2.185	1.00
106_G	110_R	2.135	1.00
51_W	55_N	2.113	1.00
113_W	204_I	2.086	1.00
88_I	103_A	1.997	1.00
43_Q	46_L	1.991	1.00
97_A	108_V	1.974	1.00
390_T	394_K	1.973	1.00
112_L	201_A	1.946	1.00
38_F	84_E	1.938	1.00
95_K	117_L	1.933	1.00
156_E	168_L	1.932	1.00
62_R	65_R	1.929	1.00
104_E	107_E	1.928	1.00
42_K	46_L	1.921	1.00
43_Q	47_N	1.913	1.00
269_K	273_K	1.899	1.00
159_V	169_I	1.882	1.00
40_Q	44_D	1.867	1.00
157_M	192_G	1.864	1.00
391_S	394_K	1.856	1.00
42_K	195_T	1.853	1.00
42_K	168_L	1.847	1.00
85_M	100_E	1.832	1.00
80_I	193_I	1.827	1.00
45_A	193_I	1.815	1.00
89_T	98_Y	1.812	1.00
96_L	198_T	1.807	1.00
182_A	426_V	1.792	1.00
96_L	153_V	1.785	1.00
155_L	183_S	1.784	1.00
99_I	129_L	1.749	1.00
172_S	175_N	1.738	1.00
46_L	50_K	1.733	1.00
47_N	50_K	1.723	1.00
49_L	436_F	1.720	1.00
425_R	429_T	1.717	1.00
342_A	394_K	1.708	1.00
82_L	193_I	1.699	1.00
383_R	387_G	1.699	1.00
379_R	383_R	1.669	1.00
61_I	193_I	1.663	1.00
90_V	111_T	1.639	1.00
107_E	110_R	1.638	1.00
97_A	199_F	1.637	1.00
95_K	203_P	1.634	1.00
134_L	186_G	1.622	1.00
41_N	44_D	1.609	1.00
261_K	265_K	1.606	1.00
156_E	195_T	1.602	1.00
421_E	424_R	1.588	1.00
133_T	152_L	1.574	1.00
134_L	194_V	1.566	1.00
50_K	53_R	1.563	1.00
52_A	78_L	1.563	1.00
428_T	434_N	1.549	1.00
111_T	115_Y	1.525	1.00
390_T	414_T	1.524	1.00
82_L	85_M	1.519	1.00
407_E	440_Q	1.517	1.00
151_S	202_V	1.508	1.00
154_Q	172_S	1.505	1.00
91_N	96_L	1.503	1.00
421_E	425_R	1.463	1.00
45_A	158_I	1.459	1.00
51_W	57_V	1.453	1.00
158_I	195_T	1.451	1.00
183_S	192_G	1.435	1.00
132_L	148_T	1.428	1.00
88_I	111_T	1.425	1.00
306_K	310_S	1.424	1.00
422_R	425_R	1.418	1.00
100_E	103_A	1.417	1.00
345_G	349_R	1.417	1.00
49_L	53_R	1.414	1.00
133_T	199_F	1.399	1.00
171_V	176_H	1.396	1.00
37_V	78_L	1.381	1.00
386_E	390_T	1.373	1.00
424_R	428_T	1.372	1.00
346_A	349_R	1.356	1.00
99_I	199_F	1.350	1.00
152_L	155_L	1.349	1.00
171_V	180_F	1.346	1.00
168_L	195_T	1.342	1.00
160_A	430_Y	1.340	1.00
427_K	434_N	1.322	1.00
227_Q	230_A	1.321	1.00
342_A	345_G	1.316	1.00
240_S	244_W	1.314	1.00
374_S	377_E	1.314	1.00
225_T	228_N	1.307	1.00
49_L	193_I	1.306	1.00
419_N	422_R	1.303	1.00
231_P	234_D	1.299	1.00
220_E	224_N	1.296	1.00
127_V	132_L	1.287	1.00
382_V	386_E	1.287	1.00
49_L	158_I	1.287	1.00
338_V	342_A	1.286	1.00
172_S	176_H	1.283	1.00
50_K	54_E	1.282	1.00
232_Y	235_D	1.277	1.00
38_F	81_D	1.277	1.00
412_P	416_Y	1.276	1.00
110_R	114_Q	1.272	1.00
86_K	100_E	1.246	1.00
221_E	224_N	1.236	1.00
45_A	80_I	1.233	1.00
260_P	263_E	1.230	1.00
87_K	103_A	1.226	1.00
99_I	108_V	1.221	1.00
39_C	48_A	1.221	1.00
90_V	97_A	1.196	1.00
380_Q	383_R	1.189	1.00
286_P	289_E	1.183	1.00
22_R	25_I	1.181	1.00
226_W	229_W	1.180	1.00
224_N	228_N	1.175	1.00
39_C	44_D	1.174	1.00
158_I	168_L	1.174	1.00
263_E	266_K	1.170	1.00
52_A	59_F	1.167	1.00
270_P	273_K	1.163	1.00
169_I	176_H	1.158	1.00
420_V	424_R	1.157	1.00
152_L	184_Q	1.153	1.00
342_A	395_E	1.146	1.00
46_L	158_I	1.144	1.00
44_D	47_N	1.144	1.00
97_A	201_A	1.144	1.00
146_G	150_D	1.144	1.00
239_S	243_F	1.143	1.00
90_V	117_L	1.142	1.00
265_K	269_K	1.139	1.00
305_M	308_S	1.139	1.00
349_R	387_G	1.128	1.00
341_Q	345_G	1.125	1.00
245_P	248_V	1.123	1.00
220_E	341_Q	1.112	1.00
183_S	194_V	1.110	1.00
350_V	387_G	1.110	1.00
159_V	430_Y	1.104	1.00
21_A	24_N	1.103	1.00
97_A	112_L	1.102	1.00
325_K	329_E	1.101	1.00
235_D	349_R	1.095	1.00
172_S	177_P	1.092	1.00
48_A	78_L	1.091	1.00
236_R	242_E	1.090	1.00
56_R	435_V	1.087	1.00
272_L	276_S	1.083	1.00
48_A	80_I	1.083	1.00
425_R	428_T	1.080	1.00
391_S	395_E	1.077	1.00
59_F	80_I	1.073	1.00
53_R	435_V	1.073	1.00
241_I	244_W	1.062	1.00
376_G	379_R	1.056	1.00
411_W	415_Y	1.043	1.00
63_G	128_G	1.034	1.00
117_L	203_P	1.030	1.00
412_P	415_Y	1.021	1.00
133_T	148_T	1.017	1.00
287_F	290_A	1.016	1.00
387_G	390_T	1.015	1.00
26_N	29_L	1.008	1.00
285_T	289_E	1.007	1.00
62_R	79_V	1.002	1.00
289_E	292_T	1.001	1.00
38_F	83_S	1.000	1.00
327_F	330_H	0.996	1.00
341_Q	344_G	0.995	1.00
155_L	180_F	0.987	1.00
240_S	243_F	0.984	1.00
107_E	111_T	0.977	1.00
59_F	435_V	0.973	1.00
157_M	169_I	0.970	1.00
35_I	78_L	0.970	1.00
308_S	311_F	0.969	1.00
181_W	422_R	0.969	1.00
135_G	402_N	0.965	1.00
130_T	197_M	0.965	1.00
383_R	386_E	0.965	1.00
231_P	235_D	0.964	1.00
377_E	380_Q	0.959	1.00
236_R	239_S	0.959	1.00
82_L	101_A	0.957	1.00
109_Y	121_A	0.957	1.00
42_K	158_I	0.956	1.00
186_G	191_F	0.953	1.00
58_P	77_G	0.952	1.00
324_I	327_F	0.951	1.00
228_N	232_Y	0.950	1.00
255_G	258_V	0.949	1.00
323_T	327_F	0.948	1.00
177_P	190_N	0.947	1.00
269_K	272_L	0.944	1.00
320_A	323_T	0.944	1.00
310_S	313_E	0.944	1.00
375_P	378_K	0.942	1.00
286_P	290_A	0.941	1.00
106_G	125_A	0.940	1.00
34_D	76_N	0.938	1.00
284_T	290_A	0.937	1.00
171_V	183_S	0.936	1.00
42_K	100_E	0.933	1.00
266_K	269_K	0.932	1.00
155_L	197_M	0.929	1.00
294_F	297_P	0.928	1.00
342_A	391_S	0.926	1.00
326_H	329_E	0.918	1.00
239_S	244_W	0.909	1.00
170_T	198_T	0.908	1.00
411_W	416_Y	0.908	1.00
63_G	82_L	0.905	1.00
251_I	255_G	0.904	1.00
239_S	242_E	0.901	1.00
105_L	121_A	0.900	1.00
313_E	317_S	0.897	1.00
182_A	191_F	0.897	1.00
263_E	267_L	0.895	1.00
400_Y	405_D	0.894	1.00
325_K	328_L	0.893	1.00
410_N	413_R	0.890	1.00
344_G	348_G	0.888	1.00
57_V	78_L	0.887	1.00
346_A	391_S	0.885	1.00
129_L	199_F	0.884	1.00
105_L	132_L	0.884	1.00
45_A	82_L	0.883	1.00
21_A	25_I	0.877	1.00
317_S	320_A	0.873	1.00
223_Y	227_Q	0.870	1.00
178_D	181_W	0.869	1.00
152_L	197_M	0.864	1.00
262_T	266_K	0.859	1.00
345_G	348_G	0.857	1.00
151_S	200_K	0.852	1.00
284_T	288_I	0.851	1.00
64_G	128_G	0.851	1.00
226_W	230_A	0.850	1.00
103_A	107_E	0.849	1.00
67_S	71_F	0.846	1.00
106_G	126_N	0.846	1.00
324_I	328_L	0.843	1.00
292_T	295_N	0.842	1.00
284_T	287_F	0.842	1.00
306_K	309_G	0.841	1.00
62_R	81_D	0.840	1.00
322_S	326_H	0.839	1.00
291_V	295_N	0.837	1.00
129_L	197_M	0.837	1.00
236_R	243_F	0.835	1.00
309_G	313_E	0.835	1.00
83_S	128_G	0.834	1.00
50_K	167_D	0.834	1.00
288_I	291_V	0.831	1.00
236_R	240_S	0.831	1.00
222_V	226_W	0.829	1.00
101_A	197_M	0.827	1.00
173_C	177_P	0.824	1.00
194_V	197_M	0.821	1.00
45_A	85_M	0.820	1.00
307_R	310_S	0.820	1.00
303_Q	307_R	0.817	1.00
238_T	241_I	0.816	1.00
392_L	396_T	0.815	1.00
237_L	241_I	0.812	1.00
161_D	169_I	0.811	1.00
86_K	103_A	0.809	1.00
399_D	402_N	0.807	1.00
63_G	101_A	0.804	1.00
321_I	324_I	0.801	1.00
237_L	242_E	0.800	1.00
304_K	308_S	0.799	1.00
47_N	51_W	0.798	1.00
97_A	111_T	0.796	1.00
351_A	354_Q	0.793	1.00
39_C	82_L	0.793	1.00
34_D	77_G	0.791	1.00
219_F	223_Y	0.790	1.00
74_L	77_G	0.789	1.00
236_R	241_I	0.787	1.00
96_L	200_K	0.787	1.00
342_A	346_A	0.785	1.00
170_T	196_S	0.785	1.00
328_L	331_A	0.785	1.00
238_T	242_E	0.785	1.00
326_H	330_H	0.784	1.00
238_T	243_F	0.780	1.00
321_I	328_L	0.778	1.00
390_T	393_S	0.778	1.00
323_T	326_H	0.777	1.00
254_L	258_V	0.776	1.00
393_S	414_T	0.775	1.00
91_N	98_Y	0.775	1.00
290_A	293_F	0.772	1.00
215_G	218_D	0.772	1.00
116_G	204_I	0.769	1.00
273_K	276_S	0.768	1.00
39_C	84_E	0.765	1.00
245_P	249_N	0.765	1.00
160_A	435_V	0.764	1.00
58_P	437_R	0.762	1.00
155_L	194_V	0.762	1.00
288_I	292_T	0.762	1.00
174_S	177_P	0.761	1.00
359_Y	362_A	0.761	1.00
321_I	325_K	0.760	1.00
36_I	79_V	0.759	1.00
240_S	250_R	0.757	1.00
42_K	85_M	0.756	1.00
178_D	429_T	0.754	1.00
283_K	287_F	0.754	1.00
285_T	290_A	0.751	1.00
153_V	198_T	0.750	1.00
222_V	225_T	0.750	1.00
105_L	127_V	0.750	1.00
289_E	293_F	0.750	1.00
412_P	420_V	0.747	1.00
302_P	306_K	0.747	1.00
293_F	297_P	0.745	1.00
339_W	342_A	0.743	1.00
307_R	312_I	0.742	1.00
379_R	382_V	0.742	1.00
427_K	437_R	0.742	1.00
421_E	428_T	0.741	1.00
385_I	389_R	0.739	1.00
85_M	195_T	0.739	1.00
43_Q	168_L	0.738	1.00
375_P	379_R	0.737	1.00
400_Y	403_W	0.736	1.00
130_T	134_L	0.733	1.00
61_I	82_L	0.732	1.00
105_L	108_V	0.731	1.00
438_F	441_S	0.731	1.00
317_S	321_I	0.731	1.00
133_T	194_V	0.727	1.00
224_N	227_Q	0.721	1.00
285_T	288_I	0.720	1.00
53_R	161_D	0.720	1.00
23_T	27_L	0.718	1.00
180_F	184_Q	0.717	1.00
222_V	229_W	0.716	1.00
70_N	74_L	0.712	1.00
83_S	104_E	0.710	1.00
42_K	45_A	0.708	1.00
154_Q	196_S	0.707	1.00
319_R	323_T	0.706	1.00
338_V	341_Q	0.706	1.00
271_L	275_G	0.699	1.00
49_L	160_A	0.699	1.00
346_A	350_V	0.697	1.00
155_L	171_V	0.695	1.00
302_P	309_G	0.694	1.00
136_G	147_L	0.692	1.00
228_N	231_P	0.690	1.00
147_L	150_D	0.690	1.00
178_D	426_V	0.688	1.00
267_L	270_P	0.688	1.00
227_Q	231_P	0.688	1.00
426_V	430_Y	0.687	1.00
251_I	256_Q	0.683	1.00
337_S	341_Q	0.683	1.00
273_K	277_P	0.683	1.00
118_T	204_I	0.683	1.00
411_W	414_T	0.682	1.00
39_C	45_A	0.681	1.00
292_T	296_S	0.678	1.00
303_Q	308_S	0.676	1.00
95_K	200_K	0.676	1.00
110_R	113_W	0.676	1.00
398_G	401_V	0.674	1.00
170_T	175_N	0.674	1.00
307_R	311_F	0.673	1.00
287_F	294_F	0.673	1.00
253_A	258_V	0.673	1.00
23_T	30_E	0.673	1.00
27_L	30_E	0.671	1.00
262_T	265_K	0.669	1.00
119_L	201_A	0.668	1.00
124_I	127_V	0.667	1.00
162_E	167_D	0.665	1.00
108_V	129_L	0.665	1.00
223_Y	226_W	0.664	1.00
350_V	383_R	0.662	1.00
112_L	115_Y	0.662	1.00
272_L	275_G	0.661	1.00
318_E	322_S	0.661	1.00
285_T	293_F	0.658	1.00
283_K	289_E	0.657	1.00
304_K	307_R	0.657	1.00
302_P	310_S	0.656	1.00
210_F	255_G	0.655	1.00
387_G	391_S	0.655	1.00
378_K	382_V	0.654	1.00
318_E	324_I	0.654	1.00
237_L	240_S	0.654	1.00
90_V	115_Y	0.652	1.00
302_P	307_R	0.651	1.00
302_P	308_S	0.650	1.00
249_N	252_E	0.649	1.00
317_S	322_S	0.649	1.00
313_E	316_L	0.648	1.00
33_P	79_V	0.648	1.00
46_L	49_L	0.647	1.00
252_E	255_G	0.646	1.00
223_Y	229_W	0.645	1.00
90_V	201_A	0.644	1.00
109_Y	118_T	0.643	1.00
302_P	305_M	0.642	1.00
122_G	132_L	0.641	1.00
88_I	99_I	0.641	1.00
376_G	380_Q	0.639	1.00
108_V	119_L	0.639	1.00
281_M	284_T	0.638	1.00
305_M	311_F	0.637	1.00
339_W	343_L	0.636	1.00
303_Q	306_K	0.635	1.00
25_I	29_L	0.635	1.00
253_A	256_Q	0.635	1.00
67_S	72_S	0.634	1.00
176_H	430_Y	0.633	1.00
251_I	258_V	0.633	1.00
286_P	293_F	0.632	1.00
372_W	378_K	0.632	1.00
225_T	229_W	0.632	1.00
91_N	95_K	0.630	1.00
374_S	378_K	0.630	1.00
291_V	294_F	0.628	1.00
290_A	297_P	0.628	1.00
268_L	272_L	0.627	1.00
318_E	321_I	0.627	1.00
21_A	38_F	0.626	1.00
336_A	341_Q	0.625	1.00
434_N	437_R	0.622	1.00
219_F	222_V	0.621	1.00
401_V	404_P	0.621	1.00
416_Y	419_N	0.620	1.00
282_V	285_T	0.620	1.00
219_F	230_A	0.619	1.00
301_Q	307_R	0.619	1.00
220_E	322_S	0.619	1.00
157_M	171_V	0.618	1.00
399_D	403_W	0.618	1.00
338_V	395_E	0.618	1.00
321_I	327_F	0.617	1.00
230_A	234_D	0.616	1.00
305_M	310_S	0.616	1.00
386_E	389_R	0.614	1.00
208_S	265_K	0.614	1.00
44_D	48_A	0.609	1.00
60_R	77_G	0.608	1.00
218_D	229_W	0.606	1.00
389_R	393_S	0.604	1.00
356_A	359_Y	0.604	1.00
292_T	297_P	0.603	1.00
301_Q	304_K	0.602	1.00
191_F	426_V	0.602	1.00
323_T	328_L	0.601	1.00
223_Y	230_A	0.600	1.00
104_E	128_G	0.600	1.00
109_Y	112_L	0.599	1.00
237_L	243_F	0.598	1.00
105_L	129_L	0.597	1.00
398_G	403_W	0.595	1.00
39_C	85_M	0.595	1.00
264_L	268_L	0.595	1.00
309_G	312_I	0.594	1.00
155_L	184_Q	0.594	1.00
144_A	236_R	0.593	1.00
181_W	184_Q	0.593	1.00
218_D	222_V	0.593	1.00
304_K	310_S	0.592	1.00
409_R	413_R	0.591	1.00
230_A	233_T	0.590	1.00
228_N	278_T	0.589	1.00
92_Q	95_K	0.587	1.00
358_Y	361_D	0.587	1.00
264_L	267_L	0.585	1.00
291_V	297_P	0.585	1.00
301_Q	305_M	0.584	1.00
156_E	198_T	0.581	1.00
89_T	96_L	0.581	1.00
385_I	388_L	0.579	1.00
20_E	23_T	0.579	1.00
208_S	264_L	0.579	1.00
405_D	412_P	0.578	1.00
22_R	30_E	0.577	1.00
220_E	223_Y	0.576	1.00
281_M	285_T	0.574	1.00
427_K	431_D	0.574	1.00
283_K	288_I	0.571	1.00
257_F	264_L	0.571	1.00
336_A	339_W	0.570	1.00
64_G	104_E	0.568	1.00
42_K	196_S	0.568	1.00
70_N	73_L	0.567	1.00
287_F	291_V	0.566	1.00
381_N	385_I	0.566	1.00
320_A	328_L	0.565	1.00
250_R	257_F	0.564	1.00
270_P	274_A	0.564	1.00
213_T	252_E	0.564	1.00
89_T	92_Q	0.564	1.00
179_L	430_Y	0.562	1.00
389_R	392_L	0.562	1.00
210_F	213_T	0.561	1.00
142_T	147_L	0.561	1.00
51_W	78_L	0.560	1.00
266_K	270_P	0.559	1.00
109_Y	204_I	0.559	1.00
303_Q	309_G	0.557	1.00
222_V	227_Q	0.554	1.00
290_A	296_S	0.553	1.00
319_R	322_S	0.552	1.00
24_N	27_L	0.550	1.00
340_Q	344_G	0.549	1.00
35_I	57_V	0.548	1.00
346_A	387_G	0.546	1.00
71_F	74_L	0.546	1.00
31_R	75_N	0.546	1.00
283_K	286_P	0.546	1.00
400_Y	404_P	0.546	1.00
22_R	36_I	0.546	1.00
109_Y	113_W	0.542	1.00
284_T	293_F	0.542	1.00
251_I	257_F	0.540	1.00
399_D	404_P	0.539	1.00
251_I	254_L	0.537	1.00
260_P	266_K	0.537	1.00
106_G	124_I	0.536	1.00
412_P	417_G	0.535	1.00
398_G	404_P	0.534	1.00
294_F	305_M	0.533	1.00
221_E	225_T	0.533	1.00
236_R	244_W	0.531	1.00
393_S	396_T	0.531	1.00
283_K	293_F	0.530	1.00
58_P	438_F	0.530	1.00
253_A	257_F	0.530	1.00
386_E	410_N	0.528	1.00
269_K	276_S	0.528	1.00
229_W	233_T	0.528	1.00
304_K	311_F	0.527	1.00
41_N	85_M	0.526	1.00
99_I	103_A	0.526	1.00
286_P	291_V	0.525	1.00
397_M	404_P	0.524	1.00
422_R	429_T	0.524	1.00
413_R	420_V	0.521	1.00
381_N	384_W	0.521	1.00
392_L	395_E	0.519	1.00
139_G	142_T	0.519	1.00
363_I	367_E	0.519	1.00
304_K	309_G	0.518	1.00
210_F	214_W	0.518	1.00
316_L	320_A	0.517	1.00
59_F	78_L	0.517	1.00
274_A	277_P	0.516	0.99
175_N	400_Y	0.515	0.99
99_I	197_M	0.515	0.99
287_F	293_F	0.514	0.99
46_L	159_V	0.512	0.99
169_I	422_R	0.511	0.99
305_M	309_G	0.511	0.99
94_K	334_Q	0.510	0.99
92_Q	117_L	0.509	0.99
31_R	73_L	0.509	0.99
173_C	184_Q	0.508	0.99
284_T	291_V	0.507	0.99
88_I	100_E	0.507	0.99
22_R	26_N	0.507	0.99
307_R	313_E	0.506	0.99
186_G	189_G	0.504	0.99
145_A	202_V	0.503	0.99
353_D	356_A	0.502	0.99
259_G	263_E	0.502	0.99
418_E	421_E	0.502	0.99
309_G	315_P	0.502	0.99
315_P	318_E	0.502	0.99
398_G	402_N	0.502	0.99
25_I	28_S	0.502	0.99
57_V	77_G	0.501	0.99
252_E	256_Q	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4xloA	2	0.969	100	0.276	Contact Map
3vteA	1	0.9734	100	0.32	Contact Map
2bvfA	1	0.9512	100	0.32	Contact Map
4pvkA	1	0.9712	100	0.327	Contact Map
3popA	2	0.9623	100	0.328	Contact Map
4ud8A	1	0.9756	100	0.328	Contact Map
2ipiA	1	0.9623	100	0.331	Contact Map
2y3sA	2	0.969	100	0.332	Contact Map
4k3tA	4	0.9623	100	0.338	Contact Map
3rjaA	1	0.9712	100	0.341	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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