HEMZ - BACSU - GREMLIN Contacts

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HEMZ - Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ

UniProt:	Q796V8	Sequences: MQIKIEGIHDDRLHRPLQNIANLFYEECELAYGGEEPADFVISLALSQTDEHVTVSGEVKGTGIKEQHTKFFSPDMTEKEAFKQVKNTISYVYLNLLQAHTGITQKWGILTGIRPTKLLHKKLQSGMSKEQAHAELKKDYLIHDEKIMLMQEIVDRQLAAVPDLYRVKDEVSIYIGIPFCPTKCAYCTFPAYAIQGQAGRVGSFLWGLHYEMQKIGEWLKEHDVKVTTIYFGGGTPTSITAEEMDLLYEEMVRSFPDVKNIREITVEAGRPDTITEEKLAVLNKYDIDRISINPQSYENETLKAIGRHHTVEETIEKYHLSRQHGMNNINMDLIIGLPGEGVKEFRHSLSETEKLMPESLTVHTLSFKRASEMTRNKHKYKVAGREEVSQMMEDAVAWTKEHGYVPYYLYRQKNILGNLENVGYSLPGQESIYNIMIMEEVQTIIGIGCGAASKFIDRDTGKITHFANPKDPKSYNERFEHYTDEKIKYLEQIFEKTTKQH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	501 (463)
Sequences:	557 (456)
Seq/√Len:	21.2

BACSU - HEMZ

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
299_N	303_K	6.148	1.00
351_E	354_K	5.153	1.00
312_E	316_E	4.382	1.00
341_G	344_E	4.194	1.00
137_K	144_D	4.157	1.00
299_N	312_E	4.008	1.00
353_E	401_E	3.612	1.00
205_L	247_L	3.588	1.00
276_E	323_Q	3.476	1.00
471_D	474_S	3.455	1.00
245_D	285_Y	3.404	1.00
134_A	138_K	3.356	1.00
213_Q	250_E	3.331	1.00
202_G	243_E	3.309	1.00
356_M	426_L	3.301	1.00
328_N	359_S	3.225	1.00
175_I	251_M	3.223	1.00
245_D	284_K	3.157	1.00
313_E	316_E	3.097	1.00
437_I	444_I	2.914	0.99
206_W	246_L	2.905	0.99
282_L	287_I	2.895	0.99
335_I	345_F	2.821	0.99
299_N	311_V	2.788	0.99
360_L	399_T	2.781	0.99
298_E	347_H	2.754	0.99
152_E	400_K	2.700	0.99
237_T	266_V	2.679	0.99
210_Y	480_E	2.649	0.98
128_S	131_Q	2.629	0.98
301_T	340_E	2.617	0.98
358_E	429_Q	2.549	0.98
298_E	344_E	2.548	0.98
210_Y	483_T	2.513	0.98
276_E	280_A	2.494	0.98
346_R	350_S	2.483	0.98
212_M	447_I	2.452	0.97
119_L	132_A	2.445	0.97
322_R	358_E	2.425	0.97
315_I	351_E	2.421	0.97
469_P	482_Y	2.403	0.97
129_K	155_D	2.346	0.97
456_I	463_I	2.320	0.96
95_N	141_L	2.279	0.96
171_V	226_V	2.262	0.96
437_I	452_A	2.232	0.96
215_I	447_I	2.223	0.95
204_F	449_C	2.221	0.95
183_K	190_P	2.206	0.95
248_Y	264_I	2.171	0.95
403_G	427_P	2.140	0.94
457_D	462_K	2.139	0.94
314_T	331_M	2.086	0.94
133_H	148_M	2.083	0.94
200_R	203_S	2.077	0.93
273_T	472_P	2.041	0.93
481_H	485_E	2.008	0.92
124_Q	158_L	1.997	0.92
252_V	285_Y	1.985	0.92
347_H	351_E	1.984	0.92
241_A	281_V	1.952	0.91
266_V	282_L	1.940	0.91
292_I	321_S	1.910	0.90
207_G	476_N	1.908	0.90
457_D	460_T	1.889	0.90
405_V	427_P	1.884	0.89
479_F	483_T	1.882	0.89
119_L	136_L	1.881	0.89
482_Y	485_E	1.875	0.89
249_E	285_Y	1.856	0.89
241_A	277_E	1.824	0.88
457_D	464_T	1.818	0.88
133_H	147_I	1.800	0.87
172_S	442_Q	1.797	0.87
152_E	405_V	1.789	0.87
231_F	247_L	1.772	0.86
207_G	479_F	1.763	0.86
478_R	481_H	1.752	0.86
288_D	327_N	1.750	0.86
333_L	348_S	1.740	0.85
364_T	388_V	1.729	0.85
227_T	262_R	1.713	0.84
15_R	19_N	1.693	0.84
290_I	321_S	1.690	0.83
212_M	254_S	1.663	0.82
469_P	478_R	1.657	0.82
210_Y	214_K	1.648	0.82
252_V	264_I	1.634	0.81
364_T	392_M	1.633	0.81
280_A	284_K	1.623	0.81
446_G	451_A	1.622	0.81
209_H	246_L	1.619	0.81
301_T	344_E	1.616	0.81
335_I	395_A	1.615	0.81
377_K	380_Y	1.599	0.80
321_S	329_I	1.595	0.80
153_I	156_R	1.588	0.79
172_S	228_T	1.586	0.79
137_K	147_I	1.576	0.79
300_E	303_K	1.570	0.79
258_V	261_I	1.564	0.78
214_K	217_E	1.562	0.78
91_Y	141_L	1.558	0.78
452_A	467_A	1.556	0.78
466_F	489_Y	1.552	0.78
22_N	27_E	1.537	0.77
144_D	147_I	1.517	0.76
194_I	451_A	1.515	0.76
455_F	489_Y	1.515	0.76
245_D	281_V	1.493	0.75
343_K	346_R	1.477	0.74
171_V	219_L	1.461	0.73
227_T	442_Q	1.440	0.72
399_T	404_Y	1.439	0.72
208_L	447_I	1.438	0.72
94_L	105_Q	1.425	0.71
333_L	352_T	1.390	0.69
348_S	352_T	1.390	0.69
342_V	394_D	1.390	0.69
297_Y	352_T	1.385	0.69
473_K	477_E	1.380	0.69
455_F	490_L	1.354	0.67
480_E	483_T	1.350	0.67
176_G	207_G	1.347	0.67
14_H	18_Q	1.343	0.67
345_F	404_Y	1.337	0.66
15_R	22_N	1.330	0.66
397_A	401_E	1.325	0.66
297_Y	314_T	1.325	0.66
446_G	482_Y	1.324	0.66
333_L	349_L	1.319	0.65
244_M	281_V	1.306	0.64
431_S	449_C	1.304	0.64
245_D	249_E	1.303	0.64
468_N	486_K	1.287	0.63
211_E	486_K	1.273	0.62
455_F	466_F	1.272	0.62
127_M	131_Q	1.271	0.62
347_H	350_S	1.262	0.62
170_E	227_T	1.250	0.61
271_P	309_H	1.224	0.59
203_S	206_W	1.223	0.59
53_V	57_G	1.221	0.59
15_R	18_Q	1.214	0.59
160_A	432_I	1.212	0.59
205_L	209_H	1.197	0.58
360_L	404_Y	1.176	0.56
155_D	223_D	1.164	0.55
136_L	142_I	1.163	0.55
248_Y	252_V	1.159	0.55
182_T	185_A	1.158	0.55
350_S	353_E	1.158	0.55
315_I	319_H	1.152	0.55
90_S	118_L	1.148	0.54
136_L	140_Y	1.141	0.54
94_L	98_Q	1.135	0.53
190_P	193_A	1.131	0.53
248_Y	251_M	1.129	0.53
484_D	487_I	1.120	0.52
387_E	391_M	1.115	0.52
14_H	19_N	1.113	0.52
213_Q	253_R	1.104	0.51
352_T	360_L	1.099	0.51
353_E	360_L	1.096	0.51
431_S	442_Q	1.096	0.51
119_L	151_Q	1.094	0.51
119_L	154_V	1.094	0.51
366_S	415_I	1.094	0.51
193_A	273_T	1.092	0.51
392_M	419_L	1.087	0.50
315_I	355_L	1.081	0.50
99_A	125_S	1.081	0.50
292_I	309_H	1.073	0.49
372_E	376_N	1.068	0.49
22_N	30_L	1.068	0.49
281_V	285_Y	1.063	0.49
300_E	401_E	1.062	0.49
157_Q	409_L	1.060	0.48
204_F	469_P	1.059	0.48
241_A	244_M	1.051	0.48
349_L	398_W	1.049	0.48
409_L	437_I	1.044	0.47
171_V	224_V	1.040	0.47
136_L	150_M	1.035	0.47
261_I	414_N	1.034	0.47
297_Y	331_M	1.031	0.47
306_G	309_H	1.031	0.47
220_K	260_N	1.028	0.46
133_H	151_Q	1.009	0.45
206_W	209_H	1.008	0.45
136_L	147_I	1.005	0.45
303_K	308_H	1.002	0.45
364_T	416_L	0.999	0.44
154_V	348_S	0.995	0.44
217_E	221_E	0.983	0.43
371_S	374_T	0.983	0.43
227_T	436_M	0.975	0.43
122_K	135_E	0.973	0.43
209_H	250_E	0.971	0.43
18_Q	32_Y	0.971	0.43
119_L	348_S	0.968	0.42
292_I	358_E	0.964	0.42
150_M	238_S	0.964	0.42
238_S	449_C	0.963	0.42
476_N	480_E	0.954	0.41
393_E	397_A	0.952	0.41
237_T	391_M	0.948	0.41
135_E	139_D	0.943	0.41
19_N	30_L	0.942	0.41
398_W	402_H	0.940	0.41
242_E	275_T	0.939	0.41
359_S	476_N	0.938	0.40
12_R	21_A	0.938	0.40
359_S	414_N	0.936	0.40
114_R	338_P	0.933	0.40
364_T	438_M	0.932	0.40
399_T	402_H	0.932	0.40
349_L	394_D	0.931	0.40
42_I	54_T	0.931	0.40
11_D	14_H	0.926	0.40
425_S	430_E	0.926	0.40
438_M	467_A	0.923	0.40
147_I	159_A	0.923	0.40
241_A	245_D	0.921	0.39
48_Q	51_E	0.920	0.39
201_V	243_E	0.918	0.39
224_V	467_A	0.917	0.39
132_A	151_Q	0.917	0.39
116_T	349_L	0.914	0.39
156_R	405_V	0.909	0.39
148_M	152_E	0.907	0.38
292_I	374_T	0.902	0.38
26_E	239_I	0.901	0.38
19_N	22_N	0.901	0.38
300_E	344_E	0.900	0.38
350_S	394_D	0.895	0.38
109_I	273_T	0.893	0.38
277_E	280_A	0.891	0.37
133_H	137_K	0.886	0.37
248_Y	285_Y	0.886	0.37
144_D	148_M	0.886	0.37
225_K	260_N	0.884	0.37
466_F	490_L	0.883	0.37
88_T	96_L	0.880	0.37
23_L	105_Q	0.878	0.37
37_P	57_G	0.877	0.37
335_I	391_M	0.877	0.37
316_E	397_A	0.876	0.37
244_M	282_L	0.874	0.36
99_A	148_M	0.873	0.36
369_R	414_N	0.872	0.36
335_I	435_I	0.871	0.36
301_T	471_D	0.869	0.36
209_H	213_Q	0.867	0.36
194_I	437_I	0.866	0.36
47_S	53_V	0.866	0.36
279_L	321_S	0.864	0.36
113_I	147_I	0.863	0.36
172_S	444_I	0.863	0.36
183_K	192_Y	0.863	0.36
353_E	399_T	0.859	0.36
171_V	445_I	0.857	0.35
86_K	113_I	0.855	0.35
176_G	469_P	0.854	0.35
297_Y	351_E	0.852	0.35
147_I	258_V	0.851	0.35
340_E	344_E	0.850	0.35
19_N	32_Y	0.848	0.35
52_H	56_S	0.846	0.35
452_A	455_F	0.844	0.35
120_H	430_E	0.843	0.35
266_V	391_M	0.842	0.34
129_K	151_Q	0.841	0.34
185_A	373_M	0.839	0.34
113_I	478_R	0.839	0.34
181_P	211_E	0.835	0.34
371_S	416_L	0.834	0.34
35_E	45_A	0.834	0.34
424_Y	432_I	0.834	0.34
14_H	30_L	0.834	0.34
20_I	32_Y	0.832	0.34
202_G	246_L	0.828	0.34
132_A	154_V	0.828	0.34
97_L	211_E	0.824	0.33
322_R	329_I	0.823	0.33
348_S	362_V	0.823	0.33
157_Q	296_S	0.822	0.33
449_C	482_Y	0.821	0.33
467_A	485_E	0.818	0.33
18_Q	22_N	0.817	0.33
194_I	201_V	0.816	0.33
279_L	326_M	0.815	0.33
271_P	306_G	0.813	0.33
197_Q	200_R	0.813	0.33
327_N	429_Q	0.813	0.33
213_Q	254_S	0.809	0.33
156_R	427_P	0.808	0.32
173_I	243_E	0.807	0.32
223_D	243_E	0.803	0.32
14_H	22_N	0.803	0.32
42_I	47_S	0.802	0.32
37_P	46_L	0.801	0.32
153_I	292_I	0.801	0.32
173_I	419_L	0.800	0.32
171_V	436_M	0.798	0.32
35_E	49_T	0.798	0.32
243_E	271_P	0.793	0.32
228_T	436_M	0.790	0.31
146_K	420_E	0.789	0.31
13_L	93_Y	0.788	0.31
90_S	110_L	0.786	0.31
20_I	23_L	0.785	0.31
97_L	264_I	0.784	0.31
220_K	315_I	0.780	0.31
393_E	396_V	0.780	0.31
219_L	226_V	0.778	0.31
340_E	471_D	0.777	0.31
86_K	147_I	0.777	0.31
439_E	456_I	0.776	0.31
130_E	134_A	0.776	0.31
229_I	260_N	0.773	0.30
148_M	280_A	0.771	0.30
274_I	281_V	0.771	0.30
247_L	296_S	0.771	0.30
318_Y	464_T	0.770	0.30
280_A	324_H	0.768	0.30
367_F	374_T	0.768	0.30
123_L	154_V	0.767	0.30
120_H	190_P	0.765	0.30
193_A	379_K	0.761	0.30
350_S	398_W	0.759	0.30
474_S	478_R	0.759	0.30
243_E	419_L	0.756	0.29
39_D	49_T	0.755	0.29
118_L	142_I	0.753	0.29
315_I	359_S	0.752	0.29
248_Y	281_V	0.751	0.29
257_D	260_N	0.751	0.29
437_I	467_A	0.751	0.29
116_T	153_I	0.749	0.29
158_L	162_P	0.748	0.29
176_G	192_Y	0.745	0.29
174_Y	336_G	0.744	0.29
304_A	339_G	0.743	0.29
157_Q	446_G	0.742	0.29
27_E	69_T	0.741	0.29
177_I	438_M	0.741	0.29
42_I	53_V	0.741	0.29
219_L	224_V	0.740	0.29
18_Q	27_E	0.739	0.29
192_Y	445_I	0.737	0.28
177_I	364_T	0.737	0.28
98_Q	104_T	0.736	0.28
315_I	318_Y	0.732	0.28
273_T	364_T	0.732	0.28
322_R	357_P	0.731	0.28
50_D	53_V	0.731	0.28
362_V	395_A	0.730	0.28
41_V	46_L	0.730	0.28
183_K	436_M	0.730	0.28
335_I	453_S	0.728	0.28
130_E	354_K	0.727	0.28
30_L	48_Q	0.725	0.28
168_K	397_A	0.724	0.28
268_A	349_L	0.722	0.28
476_N	483_T	0.721	0.28
183_K	373_M	0.719	0.27
47_S	51_E	0.718	0.27
252_V	258_V	0.717	0.27
335_I	392_M	0.717	0.27
86_K	344_E	0.717	0.27
46_L	56_S	0.717	0.27
116_T	439_E	0.716	0.27
248_Y	287_I	0.715	0.27
128_S	132_A	0.715	0.27
130_E	138_K	0.715	0.27
200_R	473_K	0.713	0.27
33_G	52_H	0.713	0.27
241_A	268_A	0.712	0.27
320_L	324_H	0.711	0.27
171_V	273_T	0.711	0.27
172_S	431_S	0.710	0.27
118_L	297_Y	0.709	0.27
238_S	446_G	0.708	0.27
18_Q	29_E	0.708	0.27
276_E	324_H	0.708	0.27
210_Y	479_F	0.707	0.27
268_A	438_M	0.705	0.27
12_R	42_I	0.704	0.27
395_A	443_T	0.703	0.27
240_T	243_E	0.703	0.27
347_H	451_A	0.702	0.27
150_M	453_S	0.702	0.27
447_I	453_S	0.702	0.27
238_S	317_K	0.702	0.27
358_E	426_L	0.701	0.27
94_L	204_F	0.695	0.26
346_R	426_L	0.695	0.26
226_V	255_F	0.694	0.26
443_T	490_L	0.694	0.26
216_G	415_I	0.693	0.26
169_D	327_N	0.690	0.26
150_M	364_T	0.688	0.26
116_T	409_L	0.688	0.26
19_N	90_S	0.687	0.26
395_A	419_L	0.685	0.26
101_T	409_L	0.685	0.26
457_D	461_G	0.684	0.26
392_M	438_M	0.684	0.26
156_R	159_A	0.684	0.26
52_H	55_V	0.683	0.26
341_G	359_S	0.682	0.26
148_M	277_E	0.678	0.25
173_I	447_I	0.676	0.25
437_I	456_I	0.675	0.25
340_E	424_Y	0.675	0.25
100_H	425_S	0.674	0.25
116_T	288_D	0.672	0.25
57_G	132_A	0.672	0.25
50_D	55_V	0.672	0.25
297_Y	322_R	0.671	0.25
461_G	464_T	0.670	0.25
207_G	210_Y	0.670	0.25
103_I	273_T	0.668	0.25
238_S	437_I	0.668	0.25
346_R	394_D	0.667	0.25
251_M	264_I	0.667	0.25
178_P	422_V	0.666	0.25
25_Y	101_T	0.665	0.25
31_A	39_D	0.664	0.25
446_G	449_C	0.663	0.25
93_Y	96_L	0.663	0.25
223_D	372_E	0.662	0.25
358_E	431_S	0.661	0.24
53_V	56_S	0.660	0.24
452_A	465_H	0.658	0.24
147_I	317_K	0.658	0.24
147_I	151_Q	0.657	0.24
449_C	469_P	0.656	0.24
154_V	470_K	0.655	0.24
204_F	367_F	0.654	0.24
229_I	266_V	0.654	0.24
335_I	394_D	0.653	0.24
179_F	291_S	0.651	0.24
42_I	57_G	0.650	0.24
271_P	452_A	0.649	0.24
129_K	133_H	0.649	0.24
212_M	238_S	0.649	0.24
74_P	77_T	0.648	0.24
33_G	38_A	0.648	0.24
57_G	100_H	0.648	0.24
239_I	364_T	0.646	0.24
216_G	220_K	0.645	0.24
211_E	468_N	0.644	0.24
87_N	139_D	0.644	0.24
120_H	416_L	0.640	0.23
466_F	485_E	0.640	0.23
359_S	370_A	0.640	0.23
50_D	71_F	0.639	0.23
478_R	482_Y	0.639	0.23
314_T	318_Y	0.638	0.23
129_K	286_D	0.638	0.23
394_D	398_W	0.638	0.23
248_Y	300_E	0.637	0.23
252_V	261_I	0.636	0.23
109_I	141_L	0.635	0.23
245_D	287_I	0.635	0.23
350_S	390_Q	0.635	0.23
124_Q	441_V	0.635	0.23
19_N	23_L	0.632	0.23
370_A	414_N	0.631	0.23
435_I	439_E	0.630	0.23
182_T	199_G	0.629	0.23
41_V	71_F	0.629	0.23
345_F	366_S	0.628	0.23
373_M	415_I	0.626	0.23
160_A	164_L	0.626	0.23
204_F	431_S	0.625	0.23
48_Q	55_V	0.625	0.23
478_R	485_E	0.625	0.23
409_L	415_I	0.623	0.23
22_N	34_G	0.622	0.23
469_P	481_H	0.621	0.23
318_Y	327_N	0.621	0.23
292_I	416_L	0.621	0.23
16_P	23_L	0.620	0.23
458_R	461_G	0.620	0.23
340_E	360_L	0.618	0.22
46_L	53_V	0.617	0.22
122_K	132_A	0.617	0.22
175_I	459_D	0.617	0.22
224_V	474_S	0.616	0.22
13_L	82_F	0.615	0.22
275_T	281_V	0.615	0.22
172_S	443_T	0.614	0.22
305_I	317_K	0.614	0.22
150_M	297_Y	0.614	0.22
388_V	391_M	0.612	0.22
290_I	359_S	0.612	0.22
182_T	194_I	0.610	0.22
73_S	99_A	0.610	0.22
185_A	338_P	0.609	0.22
227_T	430_E	0.608	0.22
39_D	74_P	0.607	0.22
433_Y	444_I	0.607	0.22
173_I	226_V	0.604	0.22
117_K	440_E	0.602	0.22
192_Y	472_P	0.602	0.22
35_E	39_D	0.601	0.22
93_Y	352_T	0.601	0.22
46_L	50_D	0.600	0.22
415_I	436_M	0.600	0.22
111_T	362_V	0.598	0.22
38_A	50_D	0.598	0.22
178_P	475_Y	0.597	0.21
203_S	284_K	0.597	0.21
201_V	482_Y	0.596	0.21
204_F	482_Y	0.596	0.21
101_T	251_M	0.595	0.21
168_K	378_H	0.594	0.21
333_L	345_F	0.593	0.21
193_A	296_S	0.593	0.21
240_T	281_V	0.591	0.21
33_G	41_V	0.588	0.21
435_I	488_K	0.588	0.21
204_F	279_L	0.588	0.21
205_L	390_Q	0.586	0.21
469_P	472_P	0.586	0.21
34_G	42_I	0.585	0.21
176_G	201_V	0.585	0.21
268_A	437_I	0.584	0.21
41_V	57_G	0.584	0.21
160_A	175_I	0.584	0.21
245_D	252_V	0.583	0.21
36_E	42_I	0.583	0.21
29_E	53_V	0.583	0.21
30_L	41_V	0.582	0.21
27_E	42_I	0.581	0.21
296_S	445_I	0.580	0.21
71_F	134_A	0.580	0.21
192_Y	301_T	0.580	0.21
195_Q	212_M	0.579	0.21
35_E	48_Q	0.579	0.21
168_K	488_K	0.577	0.21
51_E	54_T	0.577	0.21
145_E	393_E	0.576	0.21
378_H	382_V	0.576	0.21
42_I	51_E	0.576	0.21
396_V	424_Y	0.575	0.21
38_A	41_V	0.575	0.21
191_A	326_M	0.575	0.21
157_Q	160_A	0.574	0.20
320_L	323_Q	0.574	0.20
35_E	99_A	0.573	0.20
148_M	284_K	0.573	0.20
305_I	309_H	0.573	0.20
36_E	73_S	0.572	0.20
204_F	321_S	0.571	0.20
291_S	439_E	0.570	0.20
362_V	399_T	0.569	0.20
182_T	462_K	0.569	0.20
313_E	490_L	0.569	0.20
31_A	52_H	0.568	0.20
241_A	275_T	0.566	0.20
14_H	32_Y	0.566	0.20
176_G	447_I	0.564	0.20
179_F	321_S	0.563	0.20
323_Q	397_A	0.563	0.20
105_Q	273_T	0.562	0.20
18_Q	30_L	0.562	0.20
46_L	220_K	0.561	0.20
150_M	298_E	0.561	0.20
441_V	461_G	0.560	0.20
118_L	132_A	0.560	0.20
177_I	450_G	0.560	0.20
172_S	227_T	0.560	0.20
144_D	253_R	0.560	0.20
469_P	485_E	0.559	0.20
195_Q	202_G	0.559	0.20
188_T	204_F	0.559	0.20
31_A	42_I	0.559	0.20
202_G	428_G	0.558	0.20
175_I	447_I	0.557	0.20
438_M	450_G	0.556	0.20
49_T	89_I	0.556	0.20
328_N	414_N	0.556	0.20
413_K	439_E	0.555	0.20
345_F	399_T	0.555	0.20
146_K	418_N	0.555	0.20
449_C	472_P	0.555	0.20
40_F	51_E	0.554	0.20
16_P	22_N	0.554	0.20
72_F	484_D	0.553	0.20
49_T	52_H	0.552	0.20
341_G	378_H	0.552	0.20
309_H	391_M	0.550	0.19
271_P	391_M	0.550	0.19
394_D	397_A	0.549	0.19
239_I	450_G	0.549	0.19
465_H	468_N	0.548	0.19
128_S	323_Q	0.547	0.19
207_G	244_M	0.547	0.19
191_A	446_G	0.546	0.19
352_T	367_F	0.544	0.19
292_I	478_R	0.544	0.19
359_S	425_S	0.543	0.19
48_Q	53_V	0.543	0.19
211_E	447_I	0.543	0.19
153_I	340_E	0.543	0.19
183_K	431_S	0.542	0.19
111_T	273_T	0.542	0.19
118_L	290_I	0.541	0.19
356_M	403_G	0.541	0.19
471_D	482_Y	0.540	0.19
21_A	37_P	0.539	0.19
29_E	40_F	0.539	0.19
150_M	157_Q	0.539	0.19
177_I	239_I	0.539	0.19
280_A	445_I	0.537	0.19
271_P	292_I	0.536	0.19
111_T	418_N	0.536	0.19
157_Q	193_A	0.536	0.19
243_E	246_L	0.535	0.19
371_S	377_K	0.535	0.19
300_E	304_A	0.535	0.19
415_I	418_N	0.534	0.19
12_R	49_T	0.533	0.19
87_N	116_T	0.533	0.19
94_L	143_H	0.533	0.19
172_S	436_M	0.533	0.19
239_I	366_S	0.533	0.19
346_R	453_S	0.532	0.19
171_V	255_F	0.532	0.19
31_A	50_D	0.532	0.19
35_E	47_S	0.532	0.19
205_L	250_E	0.532	0.19
150_M	344_E	0.531	0.19
317_K	324_H	0.530	0.19
120_H	469_P	0.529	0.19
281_V	367_F	0.529	0.19
33_G	56_S	0.528	0.19
12_R	39_D	0.527	0.18
370_A	441_V	0.527	0.18
214_K	483_T	0.527	0.18
387_E	390_Q	0.525	0.18
30_L	339_G	0.525	0.18
349_L	399_T	0.523	0.18
467_A	478_R	0.522	0.18
466_F	473_K	0.522	0.18
40_F	47_S	0.522	0.18
42_I	49_T	0.521	0.18
371_S	375_R	0.519	0.18
374_T	377_K	0.518	0.18
82_F	409_L	0.518	0.18
297_Y	479_F	0.517	0.18
21_A	33_G	0.517	0.18
49_T	56_S	0.517	0.18
89_I	259_K	0.516	0.18
292_I	306_G	0.516	0.18
319_H	354_K	0.516	0.18
36_E	45_A	0.515	0.18
93_Y	101_T	0.515	0.18
34_G	45_A	0.512	0.18
299_N	422_V	0.512	0.18
474_S	489_Y	0.511	0.18
211_E	449_C	0.510	0.18
53_V	69_T	0.510	0.18
149_L	422_V	0.509	0.18
116_T	231_F	0.509	0.18
355_L	418_N	0.508	0.18
432_I	436_M	0.508	0.18
335_I	474_S	0.508	0.18
194_I	452_A	0.507	0.18
22_N	29_E	0.506	0.18
370_A	450_G	0.505	0.18
31_A	48_Q	0.505	0.18
287_I	297_Y	0.505	0.18
183_K	474_S	0.504	0.18
210_Y	213_Q	0.504	0.18
188_T	367_F	0.503	0.18
349_L	360_L	0.503	0.18
449_C	465_H	0.503	0.18
51_E	73_S	0.503	0.18
86_K	185_A	0.502	0.18
198_A	296_S	0.502	0.18
238_S	243_E	0.502	0.18
89_I	140_Y	0.502	0.18
264_I	326_M	0.502	0.18
113_I	392_M	0.501	0.17
485_E	488_K	0.501	0.17
219_L	445_I	0.501	0.17
402_H	419_L	0.501	0.17
301_T	360_L	0.500	0.17
47_S	56_S	0.500	0.17

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1oltA	1	0.6846	100	0.74	Contact Map
4r33A	2	0.6766	100	0.839	Contact Map
1r30A	2	0.6088	100	0.864	Contact Map
2yx0A	1	0.5749	99.9	0.875	Contact Map
4rtbA	2	0.7305	99.9	0.876	Contact Map
4wcxA	1	0.7006	99.9	0.876	Contact Map
4u0oB	1	0.517	99.9	0.877	Contact Map
3t7vA	1	0.6208	99.9	0.88	Contact Map
2qgqA	1	0.499	99.9	0.881	Contact Map
4jc0A	1	0.8044	99.9	0.885	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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