YKWB - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YKWB - Uncharacterized N-acetyltransferase YkwB

UniProt:	Q796K9	Sequences: MIILKQMYVHDGRKFEALTIRNYTETDIERLISLQEECFPPPFPQELLWSEDQLASHIKTFPEGALCALINGRIIGSMTALIVQFEPDSPDHTWAQATDNGSIKNHEPHGNTLYVVDISVSPHYRKLGIGKWLMNTMYELTVDKRLERLLGGGRIPLYYKYAHEISAVQYVEDVMEGRKNDPVLSFLLRCGRSPIRVVSNYLEDKESLNYGVLMEWKNVFYKKASC	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	226 (205)
Sequences:	608 (434)
Seq/√Len:	30.3

BACSU - YKWB YHCX

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
173_D	178_R	4.183	1.00
37_E	121_S	3.905	1.00
69_L	72_G	3.763	1.00
29_E	51_E	3.685	1.00
56_S	60_T	3.476	1.00
111_N	147_E	3.390	1.00
68_A	129_I	3.052	1.00
112_T	148_R	2.950	1.00
161_Y	179_K	2.914	1.00
38_C	119_S	2.913	1.00
76_G	120_V	2.749	1.00
134_M	137_M	2.646	1.00
99_D	104_K	2.621	1.00
34_L	74_I	2.612	1.00
171_V	184_L	2.607	1.00
21_R	27_D	2.604	1.00
130_G	186_F	2.602	1.00
180_N	185_S	2.408	0.99
151_G	214_M	2.374	0.99
99_D	105_N	2.267	0.99
21_R	69_L	2.155	0.98
162_A	208_L	2.124	0.98
75_I	124_Y	2.097	0.98
78_M	115_V	2.088	0.98
73_R	123_H	2.078	0.98
30_R	74_I	1.937	0.97
78_M	137_M	1.921	0.96
20_I	68_A	1.887	0.96
155_I	214_M	1.820	0.95
187_L	190_C	1.819	0.95
167_A	197_V	1.706	0.93
142_V	220_F	1.683	0.93
82_I	146_L	1.669	0.92
81_L	105_N	1.653	0.92
98_T	105_N	1.653	0.92
75_I	129_I	1.633	0.91
57_H	79_T	1.607	0.91
51_E	55_A	1.601	0.90
19_T	69_L	1.590	0.90
138_Y	190_C	1.563	0.89
184_L	194_P	1.544	0.89
171_V	212_V	1.537	0.89
83_V	97_A	1.471	0.86
81_L	103_I	1.470	0.86
41_P	206_E	1.465	0.86
115_V	134_M	1.429	0.85
78_M	134_M	1.419	0.84
151_G	212_V	1.415	0.84
115_V	137_M	1.408	0.84
25_E	55_A	1.405	0.84
155_I	184_L	1.378	0.82
149_L	192_R	1.375	0.82
33_S	73_R	1.366	0.82
98_T	116_V	1.355	0.81
23_Y	67_C	1.352	0.81
154_R	207_S	1.319	0.79
85_F	90_P	1.294	0.78
115_V	132_W	1.283	0.77
37_E	123_H	1.272	0.77
82_I	144_K	1.263	0.76
57_H	102_S	1.244	0.75
58_I	74_I	1.243	0.75
158_Y	162_A	1.235	0.75
173_D	179_K	1.220	0.74
203_E	209_N	1.217	0.74
99_D	103_I	1.214	0.73
113_L	146_L	1.199	0.72
109_H	200_N	1.197	0.72
166_S	169_Q	1.175	0.71
95_A	100_N	1.170	0.71
55_A	59_K	1.160	0.70
194_P	212_V	1.129	0.68
145_R	221_Y	1.119	0.67
32_I	35_Q	1.114	0.67
179_K	211_G	1.100	0.66
18_L	68_A	1.092	0.65
66_L	136_T	1.082	0.64
150_L	188_L	1.072	0.64
194_P	214_M	1.069	0.63
115_V	192_R	1.058	0.63
80_A	220_F	1.058	0.63
73_R	124_Y	1.056	0.63
20_I	132_W	1.054	0.62
93_T	96_Q	1.051	0.62
81_L	116_V	1.049	0.62
135_N	138_Y	1.046	0.62
165_I	173_D	1.044	0.62
187_L	192_R	1.039	0.61
93_T	200_N	1.031	0.61
147_E	221_Y	1.026	0.60
78_M	132_W	1.022	0.60
53_Q	209_N	1.022	0.60
28_I	54_L	1.020	0.60
22_N	66_L	1.000	0.58
158_Y	167_A	0.995	0.58
85_F	89_S	0.981	0.57
21_R	101_G	0.974	0.56
152_G	211_G	0.972	0.56
37_E	99_D	0.971	0.56
18_L	80_A	0.968	0.56
50_S	76_G	0.960	0.55
16_E	71_N	0.956	0.55
61_F	144_K	0.955	0.55
70_I	75_I	0.952	0.54
57_H	81_L	0.950	0.54
98_T	102_S	0.950	0.54
76_G	129_I	0.948	0.54
134_M	190_C	0.936	0.53
136_T	185_S	0.935	0.53
57_H	103_I	0.932	0.53
61_F	64_G	0.926	0.52
66_L	140_L	0.924	0.52
139_E	143_D	0.918	0.52
25_E	59_K	0.914	0.51
85_F	88_D	0.911	0.51
128_G	132_W	0.906	0.51
159_Y	206_E	0.906	0.51
76_G	155_I	0.905	0.51
14_K	200_N	0.897	0.50
86_E	147_E	0.887	0.49
35_Q	39_F	0.880	0.49
200_N	217_K	0.878	0.49
21_R	67_C	0.878	0.49
127_L	135_N	0.876	0.48
131_K	185_S	0.866	0.48
31_L	77_S	0.865	0.48
103_I	116_V	0.864	0.47
23_Y	31_L	0.858	0.47
196_R	213_L	0.857	0.47
35_Q	48_L	0.855	0.47
87_P	107_E	0.855	0.47
66_L	74_I	0.854	0.47
84_Q	107_E	0.853	0.47
61_F	149_L	0.850	0.46
149_L	186_F	0.848	0.46
138_Y	184_L	0.844	0.46
148_R	215_E	0.841	0.46
49_W	57_H	0.836	0.45
167_A	210_Y	0.833	0.45
112_T	215_E	0.831	0.45
163_H	179_K	0.820	0.44
120_V	168_V	0.820	0.44
115_V	149_L	0.815	0.44
18_L	70_I	0.811	0.43
75_I	107_E	0.810	0.43
100_N	105_N	0.793	0.42
37_E	206_E	0.790	0.42
63_E	118_I	0.785	0.41
142_V	168_V	0.784	0.41
53_Q	183_V	0.782	0.41
48_L	141_T	0.775	0.40
51_E	179_K	0.775	0.40
87_P	90_P	0.772	0.40
134_M	187_L	0.769	0.40
123_H	147_E	0.754	0.39
109_H	163_H	0.753	0.39
91_D	196_R	0.750	0.39
71_N	100_N	0.749	0.38
25_E	179_K	0.745	0.38
23_Y	79_T	0.742	0.38
132_W	192_R	0.740	0.38
83_V	90_P	0.739	0.38
134_M	138_Y	0.737	0.38
156_P	207_S	0.736	0.38
52_D	107_E	0.729	0.37
58_I	127_L	0.728	0.37
54_L	116_V	0.726	0.37
95_A	157_L	0.724	0.37
59_K	175_M	0.724	0.37
138_Y	192_R	0.724	0.37
131_K	189_R	0.723	0.37
93_T	198_V	0.721	0.36
107_E	144_K	0.717	0.36
57_H	77_S	0.711	0.36
68_A	76_G	0.709	0.36
137_M	149_L	0.707	0.35
104_K	150_L	0.707	0.35
67_C	151_G	0.703	0.35
98_T	101_G	0.703	0.35
101_G	105_N	0.703	0.35
37_E	74_I	0.702	0.35
125_R	188_L	0.700	0.35
95_A	205_K	0.700	0.35
95_A	123_H	0.700	0.35
134_M	192_R	0.699	0.35
15_F	67_C	0.697	0.35
42_P	194_P	0.694	0.34
120_V	157_L	0.691	0.34
86_E	96_Q	0.691	0.34
155_I	167_A	0.690	0.34
34_L	121_S	0.686	0.34
35_Q	141_T	0.684	0.34
151_G	194_P	0.683	0.34
34_L	38_C	0.672	0.33
30_R	72_G	0.671	0.33
65_A	134_M	0.671	0.33
118_I	186_F	0.668	0.33
61_F	114_Y	0.667	0.33
35_Q	47_L	0.664	0.32
39_F	99_D	0.664	0.32
151_G	183_V	0.659	0.32
22_N	136_T	0.656	0.32
27_D	69_L	0.655	0.32
155_I	212_V	0.652	0.31
70_I	98_T	0.650	0.31
48_L	203_E	0.645	0.31
157_L	179_K	0.639	0.31
85_F	147_E	0.639	0.31
58_I	71_N	0.639	0.31
167_A	199_S	0.630	0.30
75_I	194_P	0.629	0.30
26_T	221_Y	0.624	0.30
67_C	72_G	0.624	0.30
33_S	37_E	0.620	0.29
65_A	187_L	0.614	0.29
139_E	211_G	0.614	0.29
82_I	107_E	0.614	0.29
32_I	167_A	0.610	0.29
63_E	140_L	0.609	0.29
175_M	191_G	0.608	0.29
195_I	217_K	0.608	0.29
35_Q	119_S	0.607	0.28
84_Q	87_P	0.606	0.28
185_S	194_P	0.605	0.28
32_I	36_E	0.603	0.28
40_P	148_R	0.603	0.28
19_T	100_N	0.602	0.28
153_G	214_M	0.602	0.28
78_M	187_L	0.601	0.28
183_V	201_Y	0.600	0.28
79_T	103_I	0.598	0.28
85_F	111_N	0.598	0.28
204_D	207_S	0.598	0.28
32_I	48_L	0.597	0.28
25_E	123_H	0.597	0.28
19_T	95_A	0.597	0.28
101_G	120_V	0.595	0.28
123_H	143_D	0.592	0.27
80_A	140_L	0.592	0.27
207_S	218_N	0.585	0.27
50_S	205_K	0.584	0.27
118_I	157_L	0.583	0.27
78_M	140_L	0.581	0.27
16_E	70_I	0.581	0.27
79_T	192_R	0.579	0.27
23_Y	77_S	0.576	0.26
39_F	57_H	0.573	0.26
34_L	193_S	0.572	0.26
188_L	194_P	0.570	0.26
53_Q	117_D	0.569	0.26
184_L	221_Y	0.567	0.26
65_A	103_I	0.567	0.26
185_S	188_L	0.566	0.26
17_A	159_Y	0.562	0.26
67_C	76_G	0.561	0.26
95_A	118_I	0.559	0.25
149_L	190_C	0.558	0.25
184_L	214_M	0.556	0.25
115_V	187_L	0.555	0.25
164_E	205_K	0.555	0.25
31_L	47_L	0.552	0.25
57_H	219_V	0.552	0.25
92_H	216_W	0.551	0.25
132_W	137_M	0.550	0.25
31_L	70_I	0.550	0.25
18_L	164_E	0.548	0.25
174_V	211_G	0.547	0.25
189_R	220_F	0.547	0.25
138_Y	187_L	0.543	0.24
155_I	207_S	0.542	0.24
50_S	164_E	0.539	0.24
81_L	215_E	0.539	0.24
21_R	148_R	0.538	0.24
52_D	143_D	0.537	0.24
35_Q	38_C	0.535	0.24
115_V	138_Y	0.535	0.24
30_R	145_R	0.535	0.24
31_L	67_C	0.534	0.24
50_S	53_Q	0.531	0.24
81_L	166_S	0.530	0.24
161_Y	164_E	0.529	0.24
68_A	180_N	0.529	0.24
128_G	141_T	0.529	0.24
49_W	77_S	0.528	0.24
83_V	89_S	0.528	0.24
201_Y	216_W	0.528	0.24
140_L	144_K	0.525	0.23
113_L	172_E	0.523	0.23
64_G	114_Y	0.522	0.23
69_L	101_G	0.522	0.23
137_M	187_L	0.521	0.23
131_K	190_C	0.521	0.23
115_V	133_L	0.520	0.23
132_W	190_C	0.518	0.23
198_V	211_G	0.518	0.23
180_N	219_V	0.517	0.23
101_G	156_P	0.515	0.23
91_D	123_H	0.513	0.23
149_L	187_L	0.513	0.23
73_R	121_S	0.513	0.23
172_E	176_E	0.510	0.23
107_E	147_E	0.509	0.23
87_P	99_D	0.509	0.23
167_A	212_V	0.507	0.22
158_Y	213_L	0.506	0.22
153_G	192_R	0.501	0.22
81_L	104_K	0.500	0.22
41_P	109_H	0.500	0.22

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2reeA	1	0.8673	100	0.612	Contact Map
1cjwA	1	0.7301	99.7	0.798	Contact Map
1kuxA	1	0.7301	99.6	0.803	Contact Map
4r3lA	1	0.6903	99.6	0.806	Contact Map
4kvxA	1	0.6593	99.6	0.808	Contact Map
4pv6C	3	0.6814	99.6	0.813	Contact Map
1n71A	4	0.7522	99.5	0.817	Contact Map
2q0yA	2	0.646	99.5	0.818	Contact Map
2cntA	1	0.6681	99.5	0.818	Contact Map
2ob0A	1	0.6991	99.5	0.819	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0079 seconds.