YVFT - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YVFT - Sensor histidine kinase YvfT

UniProt:	Q795K2	Sequences: MKKAISIFPKEFGFFPYIFLVYTIMPFLSLLKESGVKQGIGYGMLLLFVAAYRQLFCSVGKASFTYWLIVQMAVILMYSVFYNITYIYLGFFPANFVGYYKEKTNFNRAFCALIFILLFPCLYQFIANSVSLRELFSVLPFLVIMLISPFGIRSMFRRIELEAKLAQANEQIKELSKREERVRIARDLHDTLGHTLSLLTLKSQLIQRLAASDPERTKLEAKEMETSSRSALKQVRELVSDMRTVTITEELVNIQHILRAGNITFQYEGADDFSVISPVTQNIISMCMREAVTNIIKHSKATHCAITISQFADKMRIVIRDDGKGAPKEKMFGNGLWGMEERLMLIEGGLTVSDHNGTVVALTIPLIKKAE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	371 (325)
Sequences:	30278 (27267)
Seq/√Len:	1512.5

ECOLI - UHPB RCSC TORS BARA RCSD ARCB EVGS BAES NARX GLRK PHOQ ZRAS NARQ DCUS KDPD CUSS DPIB ENVZ CPXA CREC ATOS YEDV RSTB QSEC PHOR YPDA
BACSU - YVFT DESK YFIJ YXJM YDFH GLNK KINB COMP KINE LIAS YCLK KINA BCES DCTS YVRG MALK CSSS KIND YVCQ NATK CITS PHOR YKOH YYCG YRKQ YHCY RESE YCBM YXDK KINC LYTS
HALSA - Q9HQG5 Q9HQ16 Q9HRG1 Q9HQ15 Q9HQE9 O51970 Q9HRE4 Q9HR10 Q9HNM2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
314_K	363_T	4.403	1.00
320_R	359_V	3.782	1.00
203_S	224_M	3.660	1.00
318_V	361_A	3.425	1.00
318_V	359_V	3.326	1.00
351_T	361_A	3.141	1.00
340_E	344_M	3.090	1.00
207_Q	225_E	3.038	1.00
316_R	363_T	2.912	1.00
266_Q	305_A	2.893	1.00
207_Q	222_K	2.861	1.00
200_T	228_S	2.840	1.00
291_A	360_V	2.765	1.00
316_R	361_A	2.725	1.00
295_I	304_C	2.691	1.00
307_T	318_V	2.682	1.00
266_Q	303_H	2.664	1.00
268_E	307_T	2.660	1.00
339_M	350_L	2.622	1.00
303_H	322_D	2.596	1.00
199_L	228_S	2.486	1.00
311_F	316_R	2.474	1.00
299_S	322_D	2.451	1.00
287_C	343_L	2.445	1.00
211_A	218_K	2.392	1.00
268_E	305_A	2.388	1.00
343_L	362_L	2.369	1.00
206_I	221_A	2.336	1.00
343_L	348_G	2.312	1.00
352_V	360_V	2.258	1.00
353_S	359_V	2.248	1.00
349_G	363_T	2.244	1.00
309_S	316_R	2.228	1.00
200_T	229_R	2.194	1.00
204_Q	225_E	2.165	1.00
302_T	322_D	2.106	1.00
255_Q	259_R	2.077	1.00
353_S	361_A	2.067	1.00
169_N	172_I	2.024	1.00
305_A	320_R	2.012	1.00
264_T	303_H	1.978	1.00
287_C	362_L	1.962	1.00
279_V	346_I	1.954	1.00
310_Q	366_L	1.947	1.00
309_S	318_V	1.946	1.00
169_N	173_K	1.944	1.00
321_D	325_G	1.904	1.00
151_G	154_S	1.858	1.00
250_E	253_N	1.842	1.00
326_A	358_T	1.836	1.00
317_I	362_L	1.830	1.00
225_E	229_R	1.794	1.00
213_D	216_R	1.784	1.00
307_T	320_R	1.775	1.00
168_A	171_Q	1.768	1.00
207_Q	218_K	1.765	1.00
288_M	317_I	1.765	1.00
287_C	342_R	1.731	1.00
287_C	339_M	1.721	1.00
354_D	358_T	1.687	1.00
154_S	158_R	1.680	1.00
213_D	217_T	1.658	1.00
199_L	224_M	1.643	1.00
321_D	357_G	1.643	1.00
214_P	217_T	1.637	1.00
202_K	223_E	1.629	1.00
155_M	158_R	1.629	1.00
252_V	255_Q	1.622	1.00
232_L	236_R	1.576	1.00
343_L	350_L	1.573	1.00
202_K	220_E	1.565	1.00
162_E	166_A	1.565	1.00
291_A	319_I	1.560	1.00
351_T	363_T	1.560	1.00
299_S	302_T	1.544	1.00
299_S	304_C	1.537	1.00
161_L	165_L	1.520	1.00
293_T	297_K	1.505	1.00
255_Q	258_L	1.483	1.00
300_K	324_K	1.452	1.00
179_E	183_R	1.440	1.00
344_M	349_G	1.438	1.00
203_S	225_E	1.435	1.00
342_R	346_I	1.432	1.00
168_A	172_I	1.422	1.00
200_T	225_E	1.414	1.00
178_R	182_V	1.407	1.00
286_M	289_R	1.394	1.00
209_L	217_T	1.388	1.00
178_R	181_R	1.382	1.00
315_M	366_L	1.369	1.00
161_L	164_K	1.340	1.00
277_S	280_T	1.322	1.00
206_I	217_T	1.312	1.00
280_T	283_I	1.308	1.00
270_A	309_S	1.304	1.00
198_L	202_K	1.282	1.00
203_S	221_A	1.280	1.00
200_T	232_L	1.273	1.00
218_K	222_K	1.266	1.00
222_K	226_T	1.260	1.00
311_F	363_T	1.254	1.00
306_I	319_I	1.247	1.00
170_E	173_K	1.225	1.00
170_E	174_E	1.222	1.00
160_E	164_K	1.212	1.00
203_S	228_S	1.211	1.00
200_T	204_Q	1.209	1.00
284_I	364_I	1.194	1.00
292_V	304_C	1.184	1.00
269_G	308_I	1.183	1.00
181_R	185_A	1.181	1.00
279_V	284_I	1.168	1.00
158_R	162_E	1.167	1.00
343_L	364_I	1.163	1.00
337_W	341_E	1.160	1.00
352_V	358_T	1.158	1.00
171_Q	174_E	1.140	1.00
96_F	100_Y	1.129	1.00
166_A	169_N	1.123	1.00
285_S	289_R	1.118	1.00
192_L	231_A	1.116	1.00
164_K	168_A	1.108	1.00
290_E	339_M	1.107	1.00
159_I	162_E	1.103	1.00
250_E	254_I	1.099	1.00
305_A	322_D	1.095	1.00
291_A	339_M	1.093	1.00
158_R	161_L	1.087	1.00
192_L	235_V	1.087	1.00
283_I	286_M	1.081	1.00
177_K	181_R	1.078	1.00
145_M	149_P	1.077	1.00
263_I	267_Y	1.073	1.00
48_F	52_Y	1.067	1.00
223_E	227_S	1.061	1.00
154_S	159_I	1.054	1.00
180_E	183_R	1.053	1.00
215_E	218_K	1.052	1.00
203_S	207_Q	1.051	1.00
283_I	342_R	1.044	1.00
314_K	349_G	1.035	1.00
274_S	310_Q	1.028	1.00
165_L	169_N	1.028	1.00
219_L	222_K	1.020	1.00
233_K	237_E	1.017	1.00
228_S	232_L	1.016	1.00
193_G	236_R	1.015	1.00
341_E	345_L	1.013	1.00
152_I	155_M	1.005	1.00
292_V	306_I	1.004	1.00
256_H	259_R	1.004	1.00
162_E	165_L	1.003	1.00
288_M	292_V	0.999	1.00
288_M	319_I	0.999	1.00
281_Q	285_S	0.997	1.00
167_Q	171_Q	0.991	1.00
196_L	231_A	0.988	1.00
311_F	314_K	0.987	1.00
166_A	170_E	0.980	1.00
250_E	257_I	0.980	1.00
152_I	156_F	0.980	1.00
341_E	344_M	0.973	1.00
163_A	167_Q	0.969	1.00
348_G	364_I	0.965	1.00
176_S	180_E	0.961	1.00
253_N	256_H	0.955	1.00
198_L	227_S	0.954	1.00
201_L	205_L	0.954	1.00
219_L	223_E	0.951	1.00
183_R	187_D	0.950	1.00
295_I	299_S	0.944	1.00
165_L	168_A	0.942	1.00
222_K	225_E	0.940	1.00
350_L	360_V	0.930	1.00
159_I	163_A	0.929	1.00
250_E	258_L	0.925	1.00
163_A	166_A	0.923	1.00
154_S	157_R	0.923	1.00
270_A	307_T	0.922	1.00
220_E	223_E	0.922	1.00
214_P	218_K	0.921	1.00
273_F	310_Q	0.921	1.00
254_I	257_I	0.921	1.00
154_S	162_E	0.918	1.00
191_T	286_M	0.914	1.00
38_Q	41_G	0.914	1.00
283_I	346_I	0.911	1.00
92_F	96_F	0.907	1.00
216_R	219_L	0.899	1.00
226_T	230_S	0.896	1.00
176_S	179_E	0.894	1.00
177_K	180_E	0.891	1.00
284_I	315_M	0.889	1.00
284_I	317_I	0.889	1.00
95_N	99_Y	0.886	1.00
221_A	224_M	0.884	1.00
206_I	224_M	0.880	1.00
354_D	357_G	0.878	1.00
280_T	346_I	0.871	1.00
292_V	296_I	0.867	1.00
271_D	310_Q	0.865	1.00
270_A	273_F	0.865	1.00
326_A	354_D	0.860	1.00
326_A	360_V	0.858	1.00
291_A	362_L	0.857	1.00
284_I	346_I	0.856	1.00
260_A	263_I	0.851	1.00
71_Q	75_I	0.847	1.00
161_L	166_A	0.842	1.00
191_T	234_Q	0.840	1.00
67_W	71_Q	0.834	1.00
191_T	195_T	0.834	1.00
205_L	220_E	0.833	1.00
151_G	155_M	0.832	1.00
204_Q	207_Q	0.827	1.00
321_D	358_T	0.826	1.00
184_I	188_L	0.822	1.00
194_H	198_L	0.822	1.00
146_L	150_F	0.817	1.00
298_H	324_K	0.816	1.00
334_N	338_G	0.816	1.00
263_I	299_S	0.812	1.00
202_K	227_S	0.811	1.00
227_S	230_S	0.808	1.00
253_N	257_I	0.804	1.00
288_M	306_I	0.804	1.00
39_G	42_Y	0.803	1.00
236_R	240_S	0.803	1.00
323_G	357_G	0.800	1.00
207_Q	221_A	0.799	1.00
227_S	231_A	0.798	1.00
153_R	157_R	0.796	1.00
71_Q	82_Y	0.795	1.00
261_G	296_I	0.794	1.00
237_E	283_I	0.794	1.00
228_S	231_A	0.793	1.00
350_L	362_L	0.788	1.00
97_V	101_K	0.785	1.00
336_L	339_M	0.784	1.00
41_G	44_M	0.783	1.00
98_G	101_K	0.782	1.00
217_T	221_A	0.781	1.00
71_Q	76_L	0.779	1.00
202_K	224_M	0.779	1.00
223_E	226_T	0.779	1.00
230_S	234_Q	0.775	1.00
283_I	287_C	0.774	1.00
216_R	220_E	0.771	1.00
301_A	322_D	0.766	1.00
348_G	362_L	0.765	1.00
131_S	134_E	0.765	1.00
203_S	206_I	0.763	1.00
188_L	238_L	0.763	1.00
304_C	308_I	0.762	1.00
275_V	310_Q	0.761	1.00
61_K	65_T	0.756	1.00
154_S	161_L	0.755	1.00
151_G	158_R	0.750	1.00
211_A	214_P	0.750	1.00
51_A	55_L	0.746	1.00
47_L	51_A	0.744	1.00
233_K	282_N	0.739	1.00
199_L	203_S	0.739	1.00
192_L	195_T	0.733	1.00
104_T	107_N	0.732	1.00
105_N	109_A	0.728	1.00
40_I	43_G	0.725	1.00
49_V	53_R	0.725	1.00
308_I	315_M	0.722	1.00
190_D	194_H	0.718	1.00
96_F	101_K	0.718	1.00
306_I	317_I	0.717	1.00
62_A	65_T	0.715	1.00
338_G	342_R	0.712	1.00
275_V	315_M	0.712	1.00
168_A	173_K	0.708	1.00
160_E	163_A	0.708	1.00
268_E	309_S	0.707	1.00
202_K	205_L	0.705	1.00
225_E	228_S	0.700	1.00
224_M	228_S	0.699	1.00
52_Y	55_L	0.698	1.00
308_I	317_I	0.695	1.00
217_T	220_E	0.695	1.00
64_F	67_W	0.693	1.00
283_I	345_L	0.691	1.00
325_G	358_T	0.688	1.00
90_G	94_A	0.686	1.00
155_M	159_I	0.685	1.00
137_S	141_F	0.685	1.00
254_I	258_L	0.684	1.00
96_F	99_Y	0.684	1.00
195_T	231_A	0.682	1.00
238_L	242_M	0.682	1.00
167_Q	170_E	0.682	1.00
209_L	220_E	0.680	1.00
86_Y	90_G	0.680	1.00
117_L	120_P	0.677	1.00
209_L	213_D	0.674	1.00
125_F	128_N	0.673	1.00
252_V	256_H	0.669	1.00
235_V	238_L	0.666	1.00
239_V	243_R	0.664	1.00
326_A	352_V	0.662	1.00
313_D	366_L	0.661	1.00
204_Q	208_R	0.658	1.00
145_M	148_S	0.656	1.00
205_L	209_L	0.655	1.00
126_I	130_V	0.655	1.00
193_G	232_L	0.655	1.00
155_M	162_E	0.654	1.00
95_N	100_Y	0.649	1.00
231_A	234_Q	0.647	1.00
304_C	319_I	0.647	1.00
320_R	357_G	0.645	1.00
51_A	54_Q	0.643	1.00
263_I	296_I	0.640	1.00
124_Q	128_N	0.640	1.00
88_Y	92_F	0.640	1.00
94_A	99_Y	0.637	1.00
241_D	337_W	0.635	1.00
52_Y	56_F	0.633	1.00
339_M	343_L	0.632	1.00
63_S	66_Y	0.631	1.00
318_V	353_S	0.628	1.00
183_R	341_E	0.628	1.00
197_S	201_L	0.627	1.00
221_A	225_E	0.627	1.00
263_I	303_H	0.626	1.00
231_A	235_V	0.624	1.00
270_A	308_I	0.624	1.00
204_Q	229_R	0.624	1.00
99_Y	102_E	0.623	1.00
348_G	365_P	0.623	1.00
109_A	113_L	0.623	1.00
314_K	366_L	0.620	1.00
106_F	109_A	0.620	1.00
291_A	343_L	0.620	1.00
244_T	247_I	0.619	1.00
71_Q	80_V	0.618	1.00
266_Q	269_G	0.617	1.00
42_Y	45_L	0.617	1.00
50_A	54_Q	0.616	1.00
193_G	231_A	0.616	1.00
48_F	51_A	0.615	1.00
92_F	95_N	0.614	1.00
95_N	101_K	0.614	1.00
290_E	293_T	0.612	1.00
44_M	47_L	0.612	1.00
294_N	333_G	0.610	1.00
232_L	235_V	0.609	1.00
197_S	200_T	0.607	1.00
289_R	293_T	0.607	1.00
215_E	219_L	0.603	1.00
46_L	50_A	0.601	1.00
127_A	131_S	0.599	1.00
243_R	334_N	0.597	1.00
290_E	297_K	0.596	1.00
265_F	269_G	0.595	1.00
63_S	67_W	0.594	1.00
209_L	212_S	0.594	1.00
141_F	145_M	0.592	1.00
116_I	119_F	0.591	1.00
314_K	365_P	0.590	1.00
231_A	236_R	0.589	1.00
157_R	161_L	0.588	1.00
273_F	277_S	0.587	1.00
198_L	223_E	0.587	1.00
198_L	201_L	0.584	1.00
164_K	167_Q	0.583	1.00
128_N	134_E	0.583	1.00
234_Q	237_E	0.582	1.00
252_V	257_I	0.580	1.00
190_D	290_E	0.580	1.00
108_R	111_C	0.579	1.00
205_L	208_R	0.573	1.00
286_M	342_R	0.572	1.00
353_S	358_T	0.571	1.00
41_G	45_L	0.570	1.00
254_I	289_R	0.570	1.00
110_F	113_L	0.569	1.00
305_A	318_V	0.568	1.00
295_I	319_I	0.568	1.00
113_L	117_L	0.568	1.00
185_A	189_H	0.567	1.00
206_I	220_E	0.566	1.00
63_S	71_Q	0.565	1.00
98_G	102_E	0.565	1.00
85_T	89_L	0.564	1.00
271_D	274_S	0.564	1.00
89_L	93_P	0.563	1.00
138_V	149_P	0.563	1.00
179_E	182_V	0.562	1.00
107_N	111_C	0.562	1.00
209_L	216_R	0.562	1.00
126_I	129_S	0.562	1.00
63_S	70_V	0.562	1.00
94_A	101_K	0.562	1.00
93_P	96_F	0.562	1.00
257_I	260_A	0.561	1.00
252_V	269_G	0.560	1.00
140_P	144_I	0.560	1.00
128_N	132_L	0.559	1.00
78_Y	81_F	0.558	1.00
53_R	56_F	0.558	1.00
70_V	74_V	0.557	1.00
189_H	195_T	0.557	1.00
142_L	146_L	0.557	1.00
265_F	306_I	0.556	1.00
264_T	267_Y	0.555	1.00
250_E	256_H	0.555	1.00
146_L	149_P	0.554	1.00
108_R	112_A	0.554	1.00
263_I	302_T	0.554	1.00
184_I	187_D	0.553	1.00
127_A	134_E	0.553	1.00
39_G	43_G	0.552	1.00
53_R	57_C	0.551	1.00
287_C	346_I	0.549	1.00
145_M	150_F	0.548	1.00
282_N	285_S	0.548	1.00
195_T	234_Q	0.547	1.00
137_S	140_P	0.547	1.00
236_R	239_V	0.546	1.00
68_L	71_Q	0.545	1.00
42_Y	46_L	0.545	1.00
191_T	290_E	0.545	1.00
49_V	52_Y	0.544	1.00
103_K	107_N	0.543	1.00
195_T	227_S	0.543	1.00
246_T	249_E	0.543	1.00
71_Q	74_V	0.543	1.00
229_R	232_L	0.542	1.00
156_F	159_I	0.542	1.00
161_L	168_A	0.542	1.00
61_K	64_F	0.540	1.00
86_Y	91_F	0.538	1.00
130_V	134_E	0.538	1.00
263_I	304_C	0.536	1.00
87_I	94_A	0.534	1.00
206_I	209_L	0.534	1.00
138_V	142_L	0.531	1.00
95_N	98_G	0.529	1.00
105_N	108_R	0.528	1.00
139_L	143_V	0.528	1.00
141_F	144_I	0.525	1.00
138_V	141_F	0.523	1.00
293_T	298_H	0.521	1.00
129_S	132_L	0.521	1.00
316_R	351_T	0.521	1.00
152_I	158_R	0.520	1.00
181_R	186_R	0.519	1.00
62_A	66_Y	0.518	1.00
286_M	338_G	0.517	1.00
65_T	71_Q	0.517	1.00
102_E	105_N	0.516	1.00
182_V	187_D	0.516	1.00
351_T	362_L	0.516	1.00
88_Y	91_F	0.515	1.00
43_G	46_L	0.515	1.00
310_Q	315_M	0.513	1.00
260_A	296_I	0.513	1.00
45_L	48_F	0.513	1.00
91_F	95_N	0.512	1.00
187_D	194_H	0.512	1.00
338_G	341_E	0.511	1.00
78_Y	82_Y	0.509	1.00
229_R	233_K	0.509	1.00
129_S	134_E	0.509	1.00
112_A	119_F	0.509	1.00
211_A	215_E	0.508	1.00
343_L	346_I	0.508	1.00
104_T	108_R	0.507	1.00
65_T	80_V	0.507	1.00
193_G	239_V	0.507	1.00
187_D	286_M	0.505	1.00
250_E	255_Q	0.505	1.00
340_E	349_G	0.504	1.00
44_M	48_F	0.504	1.00
135_L	139_L	0.504	1.00
187_D	298_H	0.503	1.00
180_E	184_I	0.503	1.00
250_E	259_R	0.502	1.00
46_L	49_V	0.502	1.00
185_A	188_L	0.500	1.00
324_K	358_T	0.500	1.00
93_P	97_V	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ehhA	2	0.5229	100	0.441	Contact Map
4i5sA	2	0.6792	100	0.479	Contact Map
4r39A	1	0.5148	100	0.485	Contact Map
4q20A	2	0.5364	100	0.491	Contact Map
2c2aA	2	0.5553	100	0.495	Contact Map
4bixA	2	0.5418	100	0.497	Contact Map
3d36A	2	0.5175	100	0.498	Contact Map
4gczA	2	0.876	100	0.515	Contact Map
3a0rA	2	0.7951	100	0.516	Contact Map
3jz3A	2	0.3881	100	0.518	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0112 seconds.