PARE - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

PARE - DNA topoisomerase 4 subunit B

UniProt:	Q59192	Sequences: MARKQQFDYNEDAIQVLEGLEAVRKRPGMYIGSTDARGLHHLVYEIVDNSVDEVLAGHGDHIIVKIHKDNSISVQDRGRGMPTGMHKLGKPTPEVILTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLTVTIERDGFVYQQRFENGGKPVTSLEKIGKTKKTGTLTHFKPDPTMFSTTTYNFETLSERLRESAFLLKGLKIELIDERNDQREVFYYENGIEAFVAYLNEEKDVLSEVVSFEGEHHSIEVDFAFQFNDGYSENILSFVNNVRTKDGGTHESGAKTAMTRAFNEYARKVALLKEKDKNLEGTDIREGLSAIISVRIPEELLQFEGQTKGKLGTSEARSAVDAIVSEQLAYFLEENRDTATLLVKKAIKASQAREAARKAREEARSGKKRKKSEATLSGKLTPAGSRNPAKNELYLVEGDSAGGSAKQGRDRRFQAVLPLRGKVINTEKAKLADIFKNEEINTIIHAIGGGVGADFSIDDINYDKIIIMTDADTDGAHIQVLLLTFFYRYMKPLIEHGKVFIALPPLYKVSKGSGKKEIIEYAWSDEEMGDVLKKVGKGYTIQRYKGLGEMNADQLWETTMNPESRTLVRVKIDDAARVERRVTTLMGDKVEPRRKWIEKNVAFGLDEESNILENENLSVAEEV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	655 (623)
Sequences:	4782 (2007)
Seq/√Len:	80.4

ECOLI - GYRB PARE
BACSU - PARE GYRB
HALSA - Q9HR30

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
60_D	77_R	6.562	1.00
141_F	159_K	4.610	1.00
46_I	122_A	4.309	1.00
208_I	215_R	4.051	1.00
130_E	173_K	4.032	1.00
67_H	73_S	3.790	1.00
174_P	184_Y	3.699	1.00
133_T	146_R	3.691	1.00
554_A	563_V	3.421	1.00
131_W	173_K	3.268	1.00
75_Q	169_L	3.232	1.00
417_S	422_K	3.122	1.00
148_E	154_V	3.115	1.00
593_N	596_S	3.043	1.00
204_K	217_V	2.987	1.00
137_E	165_K	2.979	1.00
61_H	204_K	2.975	1.00
495_D	530_K	2.948	1.00
11_E	84_G	2.908	1.00
93_P	134_V	2.896	1.00
133_T	144_Q	2.893	1.00
144_Q	158_E	2.871	1.00
97_L	170_T	2.801	1.00
93_P	157_L	2.797	1.00
67_H	210_E	2.704	1.00
88_L	95_V	2.690	1.00
43_V	189_L	2.687	1.00
107_G	110_G	2.668	1.00
131_W	146_R	2.665	1.00
63_I	206_E	2.622	1.00
419_N	422_K	2.593	1.00
492_I	530_K	2.590	1.00
135_T	169_L	2.578	1.00
67_H	171_H	2.576	1.00
197_A	220_Y	2.575	1.00
73_S	171_H	2.556	1.00
68_K	210_E	2.512	1.00
134_V	170_T	2.511	1.00
299_R	310_N	2.511	1.00
61_H	77_R	2.502	1.00
201_K	245_E	2.489	1.00
64_V	193_L	2.401	1.00
539_Y	557_D	2.396	1.00
83_T	143_Y	2.370	1.00
155_T	158_E	2.369	1.00
425_L	479_I	2.369	1.00
93_P	136_I	2.354	1.00
63_I	75_Q	2.335	1.00
135_T	144_Q	2.324	1.00
143_Y	159_K	2.287	1.00
43_V	72_I	2.263	1.00
66_I	72_I	2.246	1.00
535_L	600_V	2.239	1.00
632_N	635_F	2.232	1.00
130_E	176_P	2.211	1.00
90_K	94_E	2.204	1.00
135_T	142_V	2.196	1.00
255_F	324_I	2.194	1.00
420_P	495_D	2.187	1.00
186_F	216_E	2.185	1.00
51_V	203_L	2.178	1.00
498_I	599_L	2.171	1.00
141_F	162_K	2.167	1.00
11_E	92_T	2.144	1.00
475_I	479_I	2.105	1.00
523_K	527_E	2.092	1.00
59_G	77_R	2.090	1.00
133_T	171_H	2.083	1.00
18_E	87_K	2.073	1.00
627_K	631_K	2.071	1.00
186_F	207_L	2.060	1.00
137_E	142_V	2.055	1.00
524_P	527_E	2.051	1.00
278_D	341_G	2.045	1.00
296_E	300_K	2.029	1.00
149_N	177_T	2.021	1.00
293_A	357_S	2.021	1.00
73_S	169_L	2.017	1.00
204_K	219_Y	2.011	1.00
416_G	443_R	1.974	1.00
159_K	162_K	1.963	1.00
67_H	71_S	1.950	1.00
135_T	171_H	1.947	1.00
243_S	254_D	1.931	1.00
542_S	551_I	1.920	1.00
436_S	584_A	1.917	1.00
81_M	96_I	1.904	1.00
413_T	438_K	1.886	1.00
269_S	283_E	1.876	1.00
399_K	402_K	1.855	1.00
543_K	570_G	1.849	1.00
142_V	163_T	1.844	1.00
271_V	328_I	1.843	1.00
63_I	208_I	1.842	1.00
246_G	355_I	1.823	1.00
427_L	451_L	1.818	1.00
294_F	364_L	1.818	1.00
479_I	497_I	1.817	1.00
427_L	475_I	1.816	1.00
22_A	101_H	1.814	1.00
145_Q	153_P	1.809	1.00
146_R	155_T	1.790	1.00
194_R	230_Y	1.779	1.00
137_E	169_L	1.778	1.00
525_L	531_V	1.774	1.00
311_L	378_A	1.767	1.00
61_H	206_E	1.765	1.00
90_K	99_V	1.758	1.00
251_I	351_A	1.738	1.00
146_R	154_V	1.729	1.00
349_R	353_D	1.719	1.00
65_K	210_E	1.713	1.00
84_G	139_D	1.704	1.00
97_L	122_A	1.702	1.00
65_K	75_Q	1.700	1.00
269_S	276_T	1.699	1.00
247_E	252_E	1.688	1.00
226_A	229_A	1.685	1.00
236_D	261_D	1.684	1.00
44_Y	189_L	1.679	1.00
609_R	612_R	1.674	1.00
515_L	531_V	1.653	1.00
533_I	602_V	1.651	1.00
556_S	559_E	1.648	1.00
363_F	367_N	1.647	1.00
479_I	492_I	1.642	1.00
247_E	250_S	1.624	1.00
367_N	370_T	1.619	1.00
18_E	88_L	1.604	1.00
142_V	161_G	1.582	1.00
546_G	552_E	1.569	1.00
65_K	208_I	1.568	1.00
144_Q	160_I	1.568	1.00
298_A	304_L	1.565	1.00
488_S	491_D	1.559	1.00
286_A	322_A	1.557	1.00
190_S	216_E	1.556	1.00
10_N	13_A	1.546	0.99
186_F	218_F	1.544	0.99
251_I	348_A	1.541	0.99
72_I	184_Y	1.534	0.99
206_E	217_V	1.517	0.99
232_N	258_Q	1.511	0.99
297_Y	371_A	1.510	0.99
122_A	132_L	1.508	0.99
560_M	564_L	1.488	0.99
245_E	254_D	1.487	0.99
198_F	230_Y	1.487	0.99
97_L	132_L	1.486	0.99
621_K	624_P	1.477	0.99
47_V	74_V	1.472	0.99
360_L	364_L	1.460	0.99
257_F	320_L	1.451	0.99
286_A	324_I	1.448	0.99
222_N	225_E	1.446	0.99
417_S	423_N	1.445	0.99
131_W	148_E	1.440	0.99
35_D	346_S	1.437	0.99
348_A	351_A	1.434	0.99
421_A	495_D	1.426	0.99
84_G	92_T	1.422	0.99
15_Q	107_G	1.418	0.99
84_G	138_R	1.415	0.99
313_G	317_R	1.403	0.99
541_V	563_V	1.403	0.99
607_A	610_V	1.381	0.99
524_P	528_H	1.379	0.99
452_R	471_E	1.379	0.99
71_S	173_K	1.377	0.99
481_G	487_F	1.373	0.99
423_N	495_D	1.367	0.99
75_Q	165_K	1.366	0.99
225_E	229_A	1.359	0.99
464_A	468_K	1.356	0.99
147_F	153_P	1.346	0.99
552_E	566_K	1.331	0.98
103_G	106_F	1.322	0.98
142_V	160_I	1.308	0.98
95_V	99_V	1.299	0.98
153_P	156_S	1.299	0.98
224_I	243_S	1.298	0.98
201_K	254_D	1.282	0.98
318_E	381_A	1.279	0.98
425_L	475_I	1.278	0.98
132_L	170_T	1.272	0.98
271_V	276_T	1.262	0.98
51_V	196_S	1.257	0.98
65_K	73_S	1.257	0.98
470_E	474_T	1.257	0.98
97_L	134_V	1.254	0.98
263_Y	396_R	1.247	0.98
455_V	472_I	1.242	0.98
420_P	423_N	1.236	0.97
306_E	310_N	1.235	0.97
497_I	518_F	1.232	0.97
85_M	89_G	1.231	0.97
574_Q	586_Q	1.229	0.97
115_G	274_V	1.225	0.97
514_L	518_F	1.217	0.97
50_S	170_T	1.216	0.97
452_R	455_V	1.213	0.97
225_E	243_S	1.212	0.97
541_V	560_M	1.207	0.97
299_R	308_D	1.205	0.97
71_S	174_P	1.204	0.97
70_N	183_T	1.203	0.97
552_E	563_V	1.201	0.97
147_F	157_L	1.201	0.97
54_V	203_L	1.201	0.97
471_E	474_T	1.200	0.97
244_F	255_F	1.199	0.97
15_Q	25_K	1.198	0.97
31_I	38_G	1.194	0.97
559_E	562_D	1.193	0.97
242_V	257_F	1.189	0.97
206_E	215_R	1.188	0.97
489_I	528_H	1.184	0.97
626_R	630_E	1.177	0.97
59_G	62_I	1.174	0.97
422_K	445_F	1.174	0.97
141_F	161_G	1.174	0.97
232_N	321_S	1.169	0.96
173_K	176_P	1.168	0.96
422_K	444_R	1.166	0.96
439_Q	584_A	1.165	0.96
71_S	171_H	1.162	0.96
8_D	13_A	1.162	0.96
588_W	594_P	1.162	0.96
540_K	551_I	1.155	0.96
541_V	554_A	1.155	0.96
267_I	287_K	1.154	0.96
518_F	531_V	1.153	0.96
359_Q	362_Y	1.143	0.96
328_I	348_A	1.141	0.96
294_F	316_I	1.140	0.96
277_K	341_G	1.137	0.96
267_I	322_A	1.136	0.96
43_V	47_V	1.132	0.96
337_G	344_G	1.132	0.96
253_V	355_I	1.131	0.96
75_Q	137_E	1.130	0.96
186_F	214_Q	1.130	0.96
137_E	166_T	1.128	0.96
554_A	560_M	1.126	0.96
66_I	70_N	1.124	0.96
278_D	337_G	1.123	0.96
424_E	498_I	1.123	0.96
251_I	328_I	1.119	0.95
47_V	193_L	1.119	0.95
252_E	327_R	1.117	0.95
58_H	79_R	1.111	0.95
145_Q	155_T	1.109	0.95
463_L	467_F	1.107	0.95
136_I	157_L	1.106	0.95
139_D	143_Y	1.106	0.95
185_N	188_T	1.105	0.95
455_V	501_T	1.104	0.95
25_K	330_E	1.102	0.95
288_T	353_D	1.100	0.95
362_Y	366_E	1.098	0.95
299_R	306_E	1.097	0.95
481_G	489_I	1.095	0.95
291_T	313_G	1.093	0.95
190_S	218_F	1.093	0.95
481_G	492_I	1.090	0.95
70_N	173_K	1.089	0.95
233_E	612_R	1.086	0.95
298_A	375_V	1.085	0.95
253_V	351_A	1.082	0.95
299_R	304_L	1.071	0.94
364_L	371_A	1.069	0.94
551_I	554_A	1.067	0.94
230_Y	612_R	1.067	0.94
138_R	166_T	1.066	0.94
337_G	341_G	1.066	0.94
67_H	70_N	1.064	0.94
193_L	207_L	1.059	0.94
427_L	471_E	1.059	0.94
562_D	566_K	1.057	0.94
373_L	376_K	1.055	0.94
71_S	131_W	1.053	0.94
23_V	100_L	1.053	0.94
356_V	360_L	1.050	0.94
561_G	565_K	1.049	0.94
14_I	92_T	1.049	0.94
146_R	158_E	1.047	0.94
147_F	155_T	1.045	0.93
511_Q	533_I	1.043	0.93
552_E	559_E	1.038	0.93
416_G	444_R	1.029	0.93
289_A	293_A	1.029	0.93
336_E	344_G	1.024	0.93
606_D	609_R	1.022	0.93
194_R	220_Y	1.022	0.93
222_N	226_A	1.016	0.92
395_A	399_K	1.016	0.92
186_F	190_S	1.010	0.92
336_E	341_G	1.009	0.92
296_E	299_R	1.007	0.92
589_E	593_N	1.004	0.92
50_S	97_L	1.002	0.92
144_Q	155_T	1.001	0.92
452_R	470_E	0.999	0.92
445_F	594_P	0.998	0.92
554_A	559_E	0.998	0.92
241_V	256_A	0.997	0.92
130_E	177_T	0.995	0.92
304_L	310_N	0.994	0.92
271_V	326_V	0.993	0.92
176_P	182_T	0.990	0.91
377_K	396_R	0.988	0.91
560_M	571_Y	0.986	0.91
86_H	92_T	0.985	0.91
399_K	414_P	0.981	0.91
137_E	163_T	0.981	0.91
564_L	573_I	0.981	0.91
334_Q	344_G	0.976	0.91
492_I	528_H	0.975	0.91
91_P	95_V	0.974	0.91
276_T	344_G	0.973	0.91
284_S	288_T	0.972	0.91
142_V	165_K	0.971	0.91
326_V	348_A	0.969	0.91
259_F	316_I	0.967	0.90
13_A	110_G	0.966	0.90
149_N	175_D	0.965	0.90
499_I	518_F	0.961	0.90
276_T	337_G	0.956	0.90
353_D	357_S	0.955	0.90
190_S	207_L	0.953	0.90
263_Y	377_K	0.952	0.90
455_V	471_E	0.951	0.90
239_S	370_T	0.951	0.90
189_L	193_L	0.949	0.90
85_M	88_L	0.949	0.90
358_E	362_Y	0.940	0.89
473_N	477_H	0.940	0.89
42_L	125_V	0.939	0.89
122_A	134_V	0.938	0.89
455_V	474_T	0.937	0.89
612_R	616_T	0.932	0.89
413_T	443_R	0.932	0.89
623_E	627_K	0.930	0.89
61_H	217_V	0.927	0.89
15_Q	87_K	0.927	0.89
54_V	59_G	0.926	0.88
81_M	97_L	0.925	0.88
83_T	138_R	0.925	0.88
384_A	388_A	0.924	0.88
284_S	353_D	0.924	0.88
60_D	204_K	0.923	0.88
350_S	354_A	0.921	0.88
8_D	11_E	0.920	0.88
455_V	469_N	0.919	0.88
136_I	168_T	0.913	0.88
46_I	97_L	0.912	0.88
108_Q	330_E	0.909	0.88
81_M	170_T	0.908	0.88
145_Q	157_L	0.908	0.88
316_I	378_A	0.906	0.87
90_K	95_V	0.904	0.87
222_N	229_A	0.903	0.87
198_F	220_Y	0.897	0.87
86_H	90_K	0.897	0.87
469_N	474_T	0.890	0.86
55_L	59_G	0.889	0.86
414_P	493_N	0.886	0.86
459_E	520_R	0.886	0.86
423_N	530_K	0.886	0.86
576_Y	586_Q	0.874	0.85
588_W	593_N	0.870	0.85
51_V	205_I	0.870	0.85
315_D	385_R	0.869	0.85
568_G	571_Y	0.869	0.85
92_T	95_V	0.868	0.85
122_A	170_T	0.867	0.85
284_S	349_R	0.867	0.85
476_I	517_F	0.866	0.85
85_M	90_K	0.865	0.85
298_A	311_L	0.864	0.85
229_A	241_V	0.862	0.85
540_K	586_Q	0.862	0.85
271_V	344_G	0.859	0.84
66_I	207_L	0.857	0.84
36_A	185_N	0.857	0.84
345_T	348_A	0.856	0.84
10_N	84_G	0.855	0.84
442_D	445_F	0.855	0.84
613_R	616_T	0.854	0.84
77_R	165_K	0.853	0.84
149_N	152_K	0.851	0.84
64_V	207_L	0.850	0.84
376_K	380_K	0.848	0.84
278_D	342_K	0.846	0.84
475_I	501_T	0.840	0.83
389_R	393_E	0.839	0.83
585_D	593_N	0.837	0.83
471_E	501_T	0.837	0.83
64_V	205_I	0.833	0.83
292_R	353_D	0.830	0.82
269_S	337_G	0.828	0.82
603_K	607_A	0.827	0.82
91_P	157_L	0.827	0.82
142_V	159_K	0.824	0.82
557_D	561_G	0.824	0.82
245_E	252_E	0.823	0.82
240_E	370_T	0.823	0.82
426_Y	599_L	0.820	0.82
614_V	618_M	0.819	0.82
439_Q	583_N	0.817	0.81
615_T	621_K	0.817	0.81
467_F	472_I	0.816	0.81
426_Y	445_F	0.816	0.81
17_L	25_K	0.815	0.81
22_A	28_G	0.812	0.81
91_P	153_P	0.811	0.81
148_E	155_T	0.809	0.81
438_K	586_Q	0.806	0.80
458_T	466_I	0.805	0.80
163_T	166_T	0.805	0.80
369_D	373_L	0.804	0.80
267_I	283_E	0.802	0.80
141_F	160_I	0.802	0.80
16_V	88_L	0.802	0.80
304_L	308_D	0.802	0.80
402_K	405_E	0.801	0.80
627_K	630_E	0.800	0.80
196_S	200_L	0.797	0.80
255_F	286_A	0.795	0.80
58_H	152_K	0.795	0.80
311_L	375_V	0.794	0.79
409_S	414_P	0.790	0.79
214_Q	631_K	0.788	0.79
357_S	361_A	0.788	0.79
521_Y	555_W	0.787	0.79
90_K	153_P	0.784	0.79
561_G	564_L	0.782	0.78
60_D	64_V	0.781	0.78
137_E	164_K	0.781	0.78
160_I	163_T	0.779	0.78
271_V	335_F	0.777	0.78
511_Q	535_L	0.776	0.78
20_L	100_L	0.776	0.78
276_T	336_E	0.775	0.78
604_I	610_V	0.774	0.78
543_K	567_V	0.773	0.78
551_I	589_E	0.772	0.78
149_N	178_M	0.772	0.78
194_R	198_F	0.772	0.78
295_N	299_R	0.770	0.77
70_N	184_Y	0.770	0.77
255_F	356_V	0.769	0.77
399_K	403_K	0.766	0.77
11_E	139_D	0.765	0.77
19_G	23_V	0.765	0.77
269_S	344_G	0.765	0.77
500_M	534_A	0.762	0.77
475_I	517_F	0.762	0.77
55_L	207_L	0.762	0.77
543_K	569_K	0.761	0.77
372_T	376_K	0.761	0.77
481_G	522_M	0.758	0.76
302_A	306_E	0.753	0.76
278_D	346_S	0.749	0.75
490_D	528_H	0.749	0.75
22_A	100_L	0.749	0.75
371_A	375_V	0.748	0.75
250_S	329_P	0.747	0.75
69_D	171_H	0.744	0.75
417_S	444_R	0.743	0.75
139_D	159_K	0.743	0.75
519_Y	610_V	0.742	0.75
172_F	184_Y	0.742	0.75
288_T	349_R	0.739	0.74
293_A	361_A	0.737	0.74
130_E	149_N	0.736	0.74
624_P	627_K	0.735	0.74
286_A	356_V	0.735	0.74
526_I	604_I	0.733	0.74
132_L	145_Q	0.733	0.74
18_E	152_K	0.732	0.74
130_E	175_D	0.729	0.73
363_F	370_T	0.729	0.73
384_A	395_A	0.727	0.73
484_G	521_Y	0.725	0.73
142_V	162_K	0.725	0.73
65_K	71_S	0.725	0.73
251_I	329_P	0.724	0.73
426_Y	588_W	0.724	0.73
269_S	334_Q	0.724	0.73
94_E	145_Q	0.722	0.73
88_L	99_V	0.722	0.73
18_E	22_A	0.722	0.73
83_T	93_P	0.721	0.73
526_I	531_V	0.721	0.73
458_T	472_I	0.719	0.72
44_Y	188_T	0.719	0.72
175_D	178_M	0.719	0.72
208_I	213_D	0.718	0.72
257_F	290_M	0.718	0.72
20_L	101_H	0.717	0.72
497_I	531_V	0.716	0.72
15_Q	18_E	0.716	0.72
16_V	95_V	0.715	0.72
437_A	448_V	0.715	0.72
384_A	391_A	0.714	0.72
293_A	360_L	0.712	0.72
84_G	143_Y	0.712	0.72
195_E	227_F	0.712	0.72
176_P	183_T	0.711	0.72
292_R	357_S	0.711	0.72
500_M	592_M	0.710	0.71
563_V	566_K	0.709	0.71
33_S	38_G	0.709	0.71
394_E	399_K	0.709	0.71
512_V	614_V	0.707	0.71
567_V	570_G	0.707	0.71
558_E	561_G	0.707	0.71
474_T	477_H	0.704	0.71
479_I	531_V	0.704	0.71
410_G	478_A	0.703	0.71
69_D	173_K	0.703	0.71
22_A	25_K	0.703	0.71
420_P	530_K	0.703	0.71
399_K	423_N	0.702	0.71
276_T	334_Q	0.702	0.71
334_Q	345_T	0.702	0.71
190_S	214_Q	0.702	0.71
253_V	352_V	0.701	0.70
33_S	344_G	0.701	0.70
415_A	493_N	0.701	0.70
470_E	473_N	0.699	0.70
633_V	636_G	0.699	0.70
567_V	571_Y	0.698	0.70
423_N	492_I	0.696	0.70
244_F	475_I	0.696	0.70
452_R	472_I	0.695	0.70
20_L	23_V	0.695	0.70
226_A	474_T	0.695	0.70
287_K	317_R	0.695	0.70
156_S	159_K	0.694	0.70
586_Q	589_E	0.694	0.70
421_A	530_K	0.694	0.70
50_S	62_I	0.692	0.69
87_K	152_K	0.690	0.69
283_E	405_E	0.689	0.69
143_Y	166_T	0.686	0.69
380_K	396_R	0.686	0.69
142_V	164_K	0.684	0.69
131_W	171_H	0.683	0.68
628_W	632_N	0.683	0.68
479_I	495_D	0.683	0.68
269_S	324_I	0.683	0.68
278_D	336_E	0.682	0.68
520_R	611_E	0.678	0.68
405_E	477_H	0.678	0.68
409_S	493_N	0.678	0.68
524_P	604_I	0.678	0.68
9_Y	14_I	0.674	0.67
97_L	145_Q	0.674	0.67
275_R	283_E	0.674	0.67
390_K	393_E	0.673	0.67
544_G	570_G	0.673	0.67
489_I	492_I	0.672	0.67
237_V	258_Q	0.672	0.67
133_T	148_E	0.670	0.67
202_G	219_Y	0.669	0.67
33_S	37_R	0.669	0.67
234_E	615_T	0.668	0.67
614_V	619_G	0.668	0.67
102_A	123_S	0.667	0.67
316_I	468_K	0.667	0.67
298_A	306_E	0.666	0.67
552_E	567_V	0.666	0.67
380_K	383_Q	0.666	0.67
560_M	570_G	0.665	0.66
283_E	293_A	0.664	0.66
628_W	633_V	0.663	0.66
402_K	409_S	0.663	0.66
102_A	106_F	0.659	0.66
302_A	305_K	0.658	0.66
605_D	609_R	0.658	0.66
425_L	497_I	0.658	0.66
442_D	594_P	0.657	0.65
93_P	145_Q	0.656	0.65
600_V	636_G	0.656	0.65
92_T	110_G	0.656	0.65
228_V	323_I	0.655	0.65
311_L	379_I	0.652	0.65
492_I	525_L	0.652	0.65
246_G	359_Q	0.651	0.65
410_G	438_K	0.650	0.65
302_A	307_K	0.650	0.65
201_K	243_S	0.650	0.65
146_R	173_K	0.650	0.65
318_E	377_K	0.649	0.65
557_D	560_M	0.649	0.65
12_D	86_H	0.647	0.64
165_K	169_L	0.647	0.64
23_V	123_S	0.647	0.64
26_R	117_L	0.645	0.64
541_V	567_V	0.645	0.64
173_K	184_Y	0.645	0.64
13_A	109_G	0.645	0.64
244_F	356_V	0.644	0.64
456_I	466_I	0.644	0.64
99_V	147_F	0.643	0.64
476_I	483_V	0.643	0.64
303_L	375_V	0.641	0.64
387_A	391_A	0.641	0.64
448_V	592_M	0.640	0.63
386_E	390_K	0.640	0.63
61_H	75_Q	0.639	0.63
175_D	276_T	0.639	0.63
36_A	188_T	0.638	0.63
189_L	205_I	0.638	0.63
326_V	352_V	0.638	0.63
207_L	216_E	0.638	0.63
399_K	404_S	0.637	0.63
609_R	613_R	0.637	0.63
424_E	496_K	0.636	0.63
73_S	131_W	0.636	0.63
240_E	367_N	0.634	0.63
379_I	389_R	0.633	0.63
517_F	522_M	0.633	0.63
618_M	622_V	0.633	0.63
106_F	118_H	0.631	0.62
130_E	146_R	0.631	0.62
268_L	608_A	0.630	0.62
73_S	210_E	0.630	0.62
379_I	383_Q	0.630	0.62
463_L	466_I	0.629	0.62
341_G	345_T	0.629	0.62
309_K	386_E	0.629	0.62
508_A	586_Q	0.627	0.62
426_Y	496_K	0.626	0.62
13_A	107_G	0.626	0.62
553_Y	586_Q	0.625	0.62
25_K	141_F	0.623	0.61
576_Y	589_E	0.623	0.61
16_V	22_A	0.622	0.61
97_L	168_T	0.622	0.61
42_L	276_T	0.621	0.61
237_V	241_V	0.621	0.61
225_E	241_V	0.620	0.61
135_T	207_L	0.620	0.61
236_D	621_K	0.619	0.61
265_E	317_R	0.618	0.61
408_L	443_R	0.618	0.61
232_N	235_K	0.617	0.61
299_R	307_K	0.617	0.61
239_S	258_Q	0.615	0.60
47_V	64_V	0.615	0.60
574_Q	588_W	0.615	0.60
85_M	93_P	0.614	0.60
140_G	164_K	0.613	0.60
94_E	156_S	0.611	0.60
96_I	170_T	0.611	0.60
331_E	458_T	0.611	0.60
452_R	501_T	0.610	0.60
46_I	124_V	0.610	0.60
91_P	156_S	0.610	0.60
145_Q	156_S	0.608	0.60
452_R	475_I	0.607	0.59
12_D	87_K	0.607	0.59
281_T	346_S	0.607	0.59
143_Y	147_F	0.606	0.59
86_H	95_V	0.605	0.59
196_S	273_N	0.605	0.59
417_S	420_P	0.604	0.59
153_P	158_E	0.604	0.59
558_E	562_D	0.603	0.59
253_V	364_L	0.602	0.59
95_V	227_F	0.601	0.59
289_A	360_L	0.601	0.59
8_D	12_D	0.600	0.59
370_T	373_L	0.600	0.59
196_S	203_L	0.600	0.59
394_E	476_I	0.600	0.59
623_E	626_R	0.598	0.58
590_T	597_R	0.598	0.58
271_V	337_G	0.597	0.58
368_R	371_A	0.597	0.58
232_N	260_N	0.594	0.58
476_I	482_G	0.593	0.58
143_Y	163_T	0.593	0.58
67_H	208_I	0.592	0.58
410_G	443_R	0.592	0.58
304_L	379_I	0.592	0.58
85_M	91_P	0.591	0.57
131_W	154_V	0.590	0.57
70_N	182_T	0.589	0.57
298_A	302_A	0.589	0.57
70_N	174_P	0.589	0.57
88_L	91_P	0.587	0.57
63_I	73_S	0.587	0.57
241_V	370_T	0.586	0.57
111_Y	329_P	0.585	0.57
89_G	152_K	0.584	0.56
369_D	372_T	0.584	0.56
13_A	108_Q	0.584	0.56
535_L	598_T	0.584	0.56
456_I	469_N	0.583	0.56
190_S	270_F	0.582	0.56
614_V	621_K	0.582	0.56
235_K	615_T	0.582	0.56
399_K	407_T	0.582	0.56
423_N	444_R	0.582	0.56
37_R	336_E	0.581	0.56
135_T	160_I	0.581	0.56
527_E	604_I	0.581	0.56
438_K	443_R	0.581	0.56
560_M	573_I	0.581	0.56
19_G	101_H	0.580	0.56
238_L	241_V	0.580	0.56
388_A	391_A	0.580	0.56
416_G	423_N	0.580	0.56
422_K	495_D	0.579	0.56
466_I	472_I	0.578	0.56
542_S	572_T	0.578	0.56
306_E	309_K	0.578	0.56
413_T	448_V	0.577	0.56
555_W	598_T	0.577	0.56
97_L	153_P	0.576	0.55
287_K	313_G	0.576	0.55
544_G	569_K	0.576	0.55
399_K	409_S	0.576	0.55
559_E	598_T	0.575	0.55
278_D	345_T	0.575	0.55
68_K	213_D	0.574	0.55
451_L	514_L	0.573	0.55
425_L	481_G	0.573	0.55
619_G	629_I	0.572	0.55
515_L	614_V	0.572	0.55
200_L	273_N	0.572	0.55
35_D	341_G	0.571	0.55
231_L	321_S	0.570	0.55
541_V	564_L	0.570	0.55
388_A	395_A	0.570	0.55
386_E	389_R	0.570	0.55
391_A	395_A	0.570	0.55
456_I	461_A	0.570	0.55
611_E	614_V	0.570	0.55
535_L	636_G	0.569	0.55
84_G	95_V	0.569	0.55
440_G	588_W	0.569	0.55
437_A	500_M	0.569	0.55
409_S	474_T	0.569	0.55
261_D	393_E	0.568	0.54
244_F	359_Q	0.567	0.54
452_R	474_T	0.567	0.54
452_R	467_F	0.567	0.54
409_S	478_A	0.567	0.54
545_S	551_I	0.567	0.54
308_D	555_W	0.565	0.54
271_V	329_P	0.563	0.54
250_S	328_I	0.563	0.54
239_S	259_F	0.563	0.54
508_A	511_Q	0.562	0.54
413_T	586_Q	0.561	0.54
555_W	563_V	0.561	0.54
83_T	141_F	0.561	0.54
90_K	156_S	0.561	0.54
70_N	131_W	0.561	0.54
402_K	407_T	0.560	0.53
555_W	560_M	0.560	0.53
50_S	168_T	0.560	0.53
427_L	431_D	0.559	0.53
16_V	194_R	0.559	0.53
37_R	277_K	0.559	0.53
555_W	559_E	0.558	0.53
490_D	495_D	0.558	0.53
406_A	409_S	0.558	0.53
408_L	411_K	0.557	0.53
501_T	511_Q	0.556	0.53
331_E	493_N	0.556	0.53
248_H	354_A	0.554	0.53
415_A	628_W	0.553	0.52
133_T	154_V	0.553	0.52
291_T	295_N	0.553	0.52
61_H	208_I	0.553	0.52
511_Q	600_V	0.553	0.52
75_Q	135_T	0.552	0.52
43_V	66_I	0.552	0.52
234_E	316_I	0.552	0.52
440_G	455_V	0.552	0.52
440_G	508_A	0.552	0.52
15_Q	108_Q	0.551	0.52
414_P	419_N	0.551	0.52
218_F	501_T	0.551	0.52
63_I	215_R	0.551	0.52
319_G	377_K	0.550	0.52
94_E	147_F	0.550	0.52
86_H	97_L	0.549	0.52
7_F	10_N	0.549	0.52
142_V	147_F	0.549	0.52
419_N	423_N	0.547	0.52
83_T	86_H	0.547	0.52
96_I	275_R	0.546	0.52
294_F	360_L	0.545	0.51
426_Y	511_Q	0.544	0.51
192_R	196_S	0.544	0.51
204_K	221_E	0.543	0.51
592_M	630_E	0.542	0.51
439_Q	443_R	0.542	0.51
37_R	345_T	0.542	0.51
564_L	571_Y	0.542	0.51
383_Q	462_K	0.541	0.51
313_G	319_G	0.541	0.51
38_G	339_T	0.540	0.51
72_I	207_L	0.540	0.51
472_I	517_F	0.540	0.51
328_I	469_N	0.539	0.51
441_R	446_Q	0.538	0.51
455_V	470_E	0.537	0.50
533_I	620_D	0.537	0.50
543_K	571_Y	0.537	0.50
227_F	452_R	0.537	0.50
187_E	190_S	0.537	0.50
409_S	415_A	0.537	0.50
307_K	310_N	0.537	0.50
138_R	253_V	0.537	0.50
582_M	587_L	0.536	0.50
526_I	602_V	0.536	0.50
411_K	431_D	0.535	0.50
519_Y	604_I	0.535	0.50
377_K	388_A	0.534	0.50
463_L	483_V	0.534	0.50
66_I	211_R	0.534	0.50
278_D	344_G	0.534	0.50
162_K	166_T	0.533	0.50
133_T	169_L	0.532	0.50
51_V	350_S	0.532	0.50
35_D	623_E	0.532	0.50
423_N	493_N	0.532	0.50
414_P	445_F	0.531	0.50
336_E	342_K	0.531	0.50
562_D	565_K	0.531	0.50
91_P	94_E	0.531	0.50
607_A	613_R	0.530	0.50
93_P	132_L	0.530	0.50
539_Y	574_Q	0.530	0.50
395_A	400_K	0.530	0.50
523_K	626_R	0.529	0.49
62_I	316_I	0.529	0.49
50_S	383_Q	0.528	0.49
393_E	400_K	0.527	0.49
303_L	379_I	0.526	0.49
53_E	57_G	0.526	0.49
466_I	501_T	0.526	0.49
63_I	204_K	0.525	0.49
354_A	358_E	0.525	0.49
585_D	589_E	0.524	0.49
65_K	207_L	0.524	0.49
46_I	274_V	0.523	0.49
60_D	164_K	0.522	0.48
64_V	212_N	0.522	0.48
19_G	25_K	0.522	0.48
396_R	486_D	0.521	0.48
186_F	211_R	0.521	0.48
53_E	79_R	0.520	0.48
59_G	78_G	0.520	0.48
90_K	508_A	0.520	0.48
190_S	227_F	0.519	0.48
28_G	499_I	0.519	0.48
94_E	114_S	0.519	0.48
501_T	508_A	0.519	0.48
425_L	492_I	0.519	0.48
606_D	610_V	0.519	0.48
63_I	74_V	0.518	0.48
17_L	28_G	0.518	0.48
399_K	493_N	0.518	0.48
382_S	386_E	0.518	0.48
417_S	421_A	0.518	0.48
516_T	618_M	0.517	0.48
269_S	612_R	0.517	0.48
312_E	392_R	0.516	0.48
620_D	624_P	0.516	0.48
16_V	19_G	0.516	0.48
329_P	351_A	0.516	0.48
197_A	221_E	0.515	0.48
283_E	362_Y	0.515	0.48
341_G	344_G	0.515	0.48
149_N	153_P	0.515	0.48
275_R	341_G	0.514	0.47
35_D	337_G	0.514	0.47
316_I	567_V	0.514	0.47
370_T	378_A	0.513	0.47
184_Y	210_E	0.513	0.47
16_V	99_V	0.513	0.47
20_L	127_A	0.512	0.47
584_A	588_W	0.512	0.47
226_A	316_I	0.511	0.47
255_F	290_M	0.511	0.47
614_V	624_P	0.511	0.47
179_F	182_T	0.511	0.47
405_E	456_I	0.511	0.47
45_E	49_N	0.510	0.47
618_M	629_I	0.510	0.47
83_T	210_E	0.510	0.47
283_E	287_K	0.508	0.47
260_N	319_G	0.508	0.47
437_A	587_L	0.508	0.47
408_L	438_K	0.508	0.47
451_L	517_F	0.507	0.47
611_E	615_T	0.507	0.47
461_A	466_I	0.507	0.47
288_T	350_S	0.507	0.47
93_P	276_T	0.507	0.47
147_F	154_V	0.507	0.47
86_H	439_Q	0.506	0.46
546_G	566_K	0.506	0.46
476_I	522_M	0.506	0.46
44_Y	205_I	0.505	0.46
164_K	240_E	0.505	0.46
19_G	22_A	0.505	0.46
104_G	114_S	0.504	0.46
482_G	487_F	0.504	0.46
16_V	544_G	0.504	0.46
408_L	413_T	0.504	0.46
81_M	93_P	0.504	0.46
316_I	382_S	0.504	0.46
239_S	242_V	0.503	0.46
88_L	508_A	0.503	0.46
47_V	519_Y	0.503	0.46
16_V	101_H	0.503	0.46
108_Q	271_V	0.503	0.46
291_T	317_R	0.502	0.46
28_G	108_Q	0.502	0.46
426_Y	594_P	0.501	0.46
302_A	310_N	0.501	0.46
289_A	356_V	0.501	0.46
400_K	403_K	0.500	0.46
544_G	551_I	0.500	0.46

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i3hA	2	0.8809	100	0.09	Contact Map
4gfhA	2	0.913	100	0.159	Contact Map
3zkbA	5	0.5878	100	0.534	Contact Map
4urlA	1	0.5557	100	0.551	Contact Map
4wubA	2	0.5802	100	0.562	Contact Map
1pvgA	2	0.5298	100	0.564	Contact Map
1zxmA	2	0.5313	100	0.57	Contact Map
3lnuA	1	0.5191	100	0.572	Contact Map
1kijA	2	0.5802	100	0.585	Contact Map
1s16A	2	0.5725	100	0.587	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0164 seconds.