GREMLIN Database
YYCG - Sensor histidine kinase YycG
UniProt: Q45614 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 611 (572)
Sequences: 5771 (5098)
Seq/√Len: 213.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
587_I590_K5.3831.00
532_K593_T4.7591.00
219_E224_N4.6691.00
399_L420_T4.6271.00
235_D238_G4.1031.00
371_E374_D3.9831.00
508_S534_E3.9341.00
274_D365_Y3.8691.00
543_V584_A3.6701.00
280_N284_A3.6291.00
478_N517_S3.5701.00
496_V574_M3.3731.00
584_A594_I3.3261.00
529_I596_F3.2471.00
496_V575_V3.1821.00
233_G238_G3.1131.00
583_W595_T3.0571.00
476_I513_H3.0231.00
452_I488_I2.9971.00
575_V596_F2.9951.00
371_E375_Q2.9591.00
572_K576_Q2.9321.00
515_T532_K2.9121.00
517_S530_S2.9071.00
262_R266_A2.8681.00
571_A582_I2.8201.00
13_K235_D2.8001.00
513_H534_E2.7981.00
488_I578_H2.6961.00
476_I515_T2.5991.00
453_Q456_R2.5901.00
517_S532_K2.5811.00
575_V580_G2.5801.00
530_S593_T2.5361.00
228_K245_N2.5271.00
526_L597_T2.4831.00
306_M310_S2.4551.00
403_A418_M2.4451.00
574_M578_H2.4201.00
488_I493_I2.4171.00
586_S592_T2.3871.00
228_K252_E2.3861.00
585_D593_T2.3541.00
538_I542_D2.3541.00
261_E264_K2.3331.00
220_L248_T2.3231.00
277_I292_A2.2831.00
586_S589_G2.2731.00
508_S512_G2.2731.00
455_V518_I2.2721.00
530_S595_T2.2671.00
450_E490_Q2.2631.00
507_Y552_R2.2571.00
586_S590_K2.1991.00
474_E513_H2.1801.00
528_Y597_T2.1671.00
533_D537_G2.1631.00
217_A247_L2.1361.00
478_N515_T2.0741.00
466_E469_K2.0731.00
451_W487_E2.0721.00
244_F247_L2.0691.00
97_D101_E2.0591.00
226_S252_E2.0361.00
373_M376_E2.0281.00
275_G295_L1.9851.00
290_S294_E1.9741.00
228_K248_T1.9391.00
492_K495_Q1.9271.00
277_I285_I1.9191.00
502_S506_K1.8771.00
580_G598_L1.8611.00
277_I362_A1.8531.00
259_E262_R1.8511.00
528_Y595_T1.8471.00
497_L529_I1.8371.00
527_L600_Y1.8201.00
382_A387_E1.8201.00
403_A414_P1.8091.00
213_M244_F1.7971.00
199_G203_A1.7841.00
539_P542_D1.7771.00
162_G169_S1.7671.00
322_D326_Q1.7491.00
581_D597_T1.7471.00
220_L247_L1.7431.00
547_F582_I1.7371.00
508_S514_V1.7331.00
403_A421_Q1.7221.00
369_E372_K1.7201.00
479_L518_I1.7131.00
396_R425_E1.7061.00
489_D492_K1.6981.00
275_G364_I1.6961.00
515_T534_E1.6921.00
496_V571_A1.6891.00
372_K376_E1.6791.00
460_L494_T1.6661.00
247_L251_L1.6641.00
540_K587_I1.6621.00
370_Q374_D1.6621.00
576_Q581_D1.6581.00
291_P294_E1.6581.00
272_M276_V1.6511.00
465_F498_D1.6491.00
545_K548_D1.6451.00
262_R265_L1.6331.00
504_A514_V1.6241.00
492_K574_M1.6121.00
396_R424_T1.5981.00
372_K375_Q1.5971.00
539_P588_E1.5931.00
538_I546_V1.5841.00
429_R491_D1.5821.00
543_V586_S1.5751.00
402_L413_A1.5471.00
217_A244_F1.5411.00
266_A270_A1.5371.00
497_L531_V1.5351.00
546_V584_A1.5331.00
228_K249_R1.5081.00
453_Q483_D1.5081.00
585_D595_T1.5061.00
344_R370_Q1.4771.00
398_Y416_F1.4701.00
395_M420_T1.4691.00
387_E390_T1.4481.00
526_L581_D1.4471.00
234_H238_G1.4421.00
455_V479_L1.4421.00
453_Q485_Y1.4391.00
493_I578_H1.4311.00
152_P162_G1.4311.00
248_T251_L1.4281.00
352_R356_K1.4171.00
458_M497_L1.4111.00
49_L53_I1.4041.00
454_I529_I1.3921.00
217_A240_L1.3871.00
451_W485_Y1.3861.00
496_V578_H1.3821.00
538_I592_T1.3711.00
206_I209_P1.3641.00
523_E528_Y1.3611.00
313_G316_E1.3591.00
455_V459_S1.3571.00
387_E391_P1.3511.00
394_T423_E1.3491.00
265_L269_I1.3471.00
584_A592_T1.3451.00
583_W597_T1.3441.00
399_L417_L1.3441.00
307_P310_S1.3401.00
497_L501_I1.3391.00
468_T514_V1.3341.00
547_F594_I1.3301.00
377_R381_V1.3261.00
458_M518_I1.3231.00
92_E105_S1.3201.00
269_I289_N1.3121.00
125_R129_T1.2881.00
96_V102_V1.2871.00
344_R365_Y1.2851.00
461_I494_T1.2851.00
410_K413_A1.2791.00
245_N248_T1.2721.00
278_A359_G1.2691.00
261_E265_L1.2681.00
575_V598_L1.2671.00
288_L292_A1.2661.00
500_I531_V1.2611.00
399_L424_T1.2601.00
500_I571_A1.2591.00
540_K543_V1.2541.00
217_A243_T1.2521.00
117_Q120_D1.2511.00
116_K120_D1.2451.00
387_E570_I1.2401.00
465_F505_L1.2391.00
495_Q574_M1.2241.00
216_Q229_V1.2191.00
9_S12_F1.2191.00
298_V302_T1.2191.00
548_D551_Y1.2151.00
512_G534_E1.2151.00
269_I287_L1.2151.00
251_L254_A1.2131.00
460_L490_Q1.2041.00
506_K554_D1.2001.00
371_E376_E1.1991.00
461_I501_I1.1951.00
497_L596_F1.1951.00
385_S390_T1.1901.00
380_F383_N1.1891.00
423_E426_R1.1861.00
122_I126_I1.1861.00
148_I151_K1.1791.00
459_S477_R1.1781.00
299_S302_T1.1781.00
397_S401_A1.1691.00
117_Q122_I1.1611.00
389_R427_M1.1591.00
547_F584_A1.1591.00
398_Y419_V1.1581.00
554_D562_G1.1571.00
546_V594_I1.1561.00
454_I527_L1.1531.00
254_A258_T1.1481.00
462_I477_R1.1471.00
458_M516_F1.1431.00
275_G289_N1.1401.00
449_R487_E1.1361.00
29_I33_F1.1331.00
384_V434_L1.1291.00
522_E600_Y1.1291.00
518_I529_I1.1191.00
418_M422_N1.1161.00
218_M239_Q1.1081.00
123_F126_I1.1071.00
500_I594_I1.1051.00
390_T397_S1.1031.00
162_G166_V1.1031.00
449_R578_H1.0931.00
434_L438_S1.0931.00
279_T285_I1.0931.00
388_L391_P1.0901.00
542_D553_V1.0881.00
399_L421_Q1.0881.00
139_D142_S1.0881.00
428_I432_N1.0851.00
402_L417_L1.0831.00
383_N549_R1.0781.00
538_I568_L1.0751.00
468_T505_L1.0741.00
288_L293_L1.0691.00
293_L300_R1.0661.00
298_V336_R1.0621.00
500_I596_F1.0611.00
253_D257_M1.0581.00
277_I289_N1.0571.00
165_Y169_S1.0541.00
214_R239_Q1.0501.00
327_Q333_E1.0501.00
57_S61_E1.0491.00
229_V241_A1.0431.00
321_E325_E1.0421.00
458_M477_R1.0411.00
406_A413_A1.0381.00
204_R208_H1.0381.00
213_M217_A1.0361.00
388_L427_M1.0361.00
225_F251_L1.0301.00
496_V596_F1.0241.00
250_E253_D1.0231.00
486_V598_L1.0221.00
119_T122_I1.0211.00
380_F385_S1.0211.00
433_D564_T1.0201.00
259_E263_R1.0181.00
121_L125_R1.0181.00
293_L299_S1.0151.00
218_M222_K1.0141.00
457_F461_I1.0071.00
552_R561_L1.0071.00
514_V518_I1.0061.00
464_R498_D1.0051.00
475_F514_V1.0041.00
583_W596_F1.0041.00
290_S293_L1.0011.00
575_V582_I0.9961.00
381_V390_T0.9961.00
53_I57_S0.9941.00
293_L303_A0.9931.00
386_H390_T0.9921.00
10_I206_I0.9891.00
269_I276_V0.9881.00
116_K119_T0.9871.00
289_N368_T0.9831.00
521_N528_Y0.9801.00
435_L564_T0.9791.00
390_T394_T0.9791.00
260_G264_K0.9781.00
493_I596_F0.9771.00
538_I543_V0.9751.00
255_Q259_E0.9741.00
421_Q425_E0.9721.00
508_S511_G0.9701.00
506_K552_R0.9701.00
229_V245_N0.9691.00
333_E371_E0.9691.00
46_E50_N0.9681.00
258_T261_E0.9681.00
387_E495_Q0.9671.00
383_N389_R0.9601.00
216_Q244_F0.9591.00
349_V359_G0.9531.00
447_F578_H0.9521.00
216_Q227_R0.9521.00
65_K68_N0.9491.00
251_L255_Q0.9461.00
50_N54_D0.9430.99
377_R383_N0.9430.99
45_Y49_L0.9380.99
435_L439_K0.9330.99
261_E266_A0.9290.99
388_L431_V0.9280.99
542_D551_Y0.9280.99
124_K127_F0.9240.99
447_F492_K0.9240.99
382_A385_S0.9230.99
203_A207_T0.9190.99
289_N366_D0.9190.99
521_N524_E0.9150.99
394_T398_Y0.9090.99
102_V107_K0.9070.99
278_A287_L0.9060.99
394_T419_V0.9060.99
278_A289_N0.9050.99
452_I493_I0.9040.99
398_Y552_R0.9020.99
279_T362_A0.9010.99
381_V393_T0.9000.99
457_F488_I0.8970.99
391_P427_M0.8970.99
278_A361_I0.8940.99
84_F88_D0.8930.99
419_V423_E0.8920.99
472_H510_E0.8890.99
149_S152_P0.8880.99
159_E162_G0.8870.99
398_Y420_T0.8860.99
213_M241_A0.8860.99
501_I516_F0.8820.99
386_H391_P0.8800.99
345_V364_I0.8740.99
393_T396_R0.8730.99
217_A221_A0.8710.99
390_T393_T0.8710.99
176_Q180_I0.8700.99
382_A388_L0.8680.99
423_E435_L0.8660.99
319_T322_D0.8650.99
258_T262_R0.8640.99
385_S389_R0.8640.99
396_R428_I0.8640.99
566_L570_I0.8630.99
378_R382_A0.8620.99
41_L44_S0.8620.99
379_E383_N0.8610.99
224_N227_R0.8600.99
79_R82_N0.8590.99
129_T132_S0.8590.99
456_R490_Q0.8560.99
525_E600_Y0.8560.99
459_S463_D0.8560.99
154_M162_G0.8540.99
183_I186_S0.8540.99
530_S585_D0.8510.99
447_F489_D0.8490.99
399_L403_A0.8460.99
383_N437_L0.8450.99
389_R428_I0.8430.99
149_S154_M0.8430.99
92_E167_V0.8420.99
445_Y492_K0.8400.99
377_R385_S0.8370.99
380_F435_L0.8350.99
387_E430_L0.8340.99
545_K551_Y0.8330.99
164_I169_S0.8330.99
420_T424_T0.8310.99
383_N387_E0.8300.99
435_L438_S0.8290.99
483_D518_I0.8280.99
330_M333_E0.8270.99
35_N38_E0.8260.99
414_P418_M0.8260.99
388_L398_Y0.8220.99
53_I56_L0.8190.99
536_I592_T0.8170.99
536_I561_L0.8160.99
269_I275_G0.8150.99
380_F390_T0.8140.99
508_S552_R0.8130.99
63_E67_D0.8100.98
447_F577_A0.8090.98
84_F87_S0.8060.98
31_V35_N0.8040.98
538_I594_I0.8030.98
424_T427_M0.8010.98
521_N530_S0.8000.98
385_S507_Y0.7980.98
472_H511_G0.7970.98
142_S146_V0.7960.98
58_Y61_E0.7950.98
383_N390_T0.7950.98
426_R430_L0.7940.98
506_K553_V0.7940.98
320_F324_V0.7930.98
285_I288_L0.7930.98
178_K181_N0.7890.98
94_S102_V0.7890.98
342_V367_V0.7830.98
33_F37_V0.7810.98
184_L187_G0.7800.98
169_S172_D0.7780.98
407_W413_A0.7780.98
162_G170_M0.7770.98
490_Q494_T0.7760.98
297_N338_D0.7760.98
507_Y554_D0.7750.98
284_A307_P0.7750.98
580_G599_P0.7740.98
380_F384_V0.7730.98
195_T199_G0.7730.98
395_M424_T0.7730.98
495_Q570_I0.7710.98
389_R435_L0.7690.98
396_R399_L0.7680.98
302_T336_R0.7680.98
264_K268_V0.7670.98
77_V84_F0.7660.98
236_E247_L0.7650.98
64_Y68_N0.7630.98
378_R441_D0.7610.98
275_G292_A0.7600.98
323_L326_Q0.7600.98
77_V104_G0.7590.98
586_S593_T0.7570.98
162_G165_Y0.7560.98
51_Q54_D0.7550.98
341_T366_D0.7540.98
379_E387_E0.7540.98
347_F360_L0.7500.97
377_R390_T0.7490.97
549_R554_D0.7490.97
119_T123_F0.7490.97
257_M261_E0.7480.97
506_K561_L0.7460.97
449_R488_I0.7450.97
139_D146_V0.7450.97
162_G168_A0.7450.97
465_F501_I0.7450.97
536_I586_S0.7420.97
185_A189_G0.7410.97
550_F566_L0.7410.97
393_T397_S0.7410.97
214_R218_M0.7400.97
240_L247_L0.7400.97
468_T475_F0.7380.97
389_R432_N0.7380.97
386_H499_N0.7370.97
398_Y423_E0.7360.97
94_S105_S0.7360.97
382_A391_P0.7360.97
147_L151_K0.7330.97
269_I278_A0.7330.97
115_G119_T0.7330.97
275_G296_L0.7310.97
381_V384_V0.7310.97
422_N460_L0.7290.97
439_K445_Y0.7290.97
367_V371_E0.7270.97
437_L441_D0.7260.97
264_K287_L0.7260.97
214_R243_T0.7260.97
385_S506_K0.7260.97
377_R389_R0.7230.97
285_I292_A0.7230.97
501_I514_V0.7200.97
507_Y536_I0.7200.97
384_V393_T0.7190.97
377_R384_V0.7190.97
423_E434_L0.7190.97
508_S536_I0.7170.97
225_F247_L0.7160.97
279_T308_I0.7160.97
139_D148_I0.7160.97
434_L439_K0.7150.97
288_L303_A0.7150.97
283_G289_N0.7150.97
289_N292_A0.7150.97
209_P235_D0.7140.97
146_V149_S0.7120.97
387_E571_A0.7110.97
516_F531_V0.7100.96
218_M246_H0.7090.96
435_L506_K0.7090.96
390_T570_I0.7080.96
220_L223_G0.7070.96
265_L268_V0.7070.96
255_Q262_R0.7050.96
231_K245_N0.7050.96
507_Y561_L0.7050.96
367_V370_Q0.7040.96
286_I359_G0.7030.96
390_T507_Y0.7000.96
182_T186_S0.7000.96
494_T498_D0.7000.96
383_N388_L0.6980.96
377_R441_D0.6970.96
278_A350_I0.6970.96
408_E413_A0.6960.96
150_A163_A0.6960.96
377_R506_K0.6950.96
523_E597_T0.6940.96
389_R495_Q0.6930.96
264_K278_A0.6930.96
341_T368_T0.6930.96
380_F502_S0.6920.96
149_S153_V0.6910.96
538_I586_S0.6900.96
48_S51_Q0.6900.96
507_Y553_V0.6890.96
377_R552_R0.6890.96
473_V505_L0.6890.96
246_H250_E0.6890.96
80_I83_D0.6880.96
57_S60_I0.6880.96
351_Q357_I0.6880.96
77_V81_L0.6860.96
382_A566_L0.6860.96
55_N59_Y0.6860.96
388_L430_L0.6830.96
387_E393_T0.6820.96
499_N564_T0.6820.96
480_P483_D0.6820.96
492_K496_V0.6790.95
148_I167_V0.6790.95
151_K154_M0.6790.95
131_Q135_R0.6790.95
493_I497_L0.6790.95
54_D58_Y0.6780.95
268_V289_N0.6780.95
507_Y551_Y0.6770.95
468_T473_V0.6770.95
382_A389_R0.6760.95
76_D80_I0.6760.95
114_A117_Q0.6750.95
143_K152_P0.6720.95
220_L225_F0.6720.95
219_E227_R0.6710.95
437_L507_Y0.6700.95
312_L317_N0.6690.95
97_D100_Y0.6690.95
92_E106_S0.6680.95
452_I457_F0.6680.95
415_R463_D0.6680.95
60_I63_E0.6670.95
427_M436_Q0.6660.95
502_S564_T0.6650.95
209_P236_E0.6640.95
387_E427_M0.6640.95
163_A169_S0.6630.95
381_V392_L0.6610.95
216_Q223_G0.6600.95
387_E423_E0.6600.95
146_V167_V0.6590.95
484_L527_L0.6580.95
449_R579_G0.6570.95
539_P553_V0.6570.95
389_R433_D0.6560.95
252_E256_A0.6550.95
382_A390_T0.6550.95
484_L518_I0.6550.95
493_I575_V0.6550.95
377_R380_F0.6540.94
121_L124_K0.6530.94
383_N554_D0.6530.94
416_F549_R0.6520.94
393_T566_L0.6510.94
56_L59_Y0.6510.94
405_G413_A0.6500.94
256_A260_G0.6500.94
383_N572_K0.6490.94
486_V527_L0.6480.94
123_F127_F0.6480.94
393_T423_E0.6470.94
424_T428_I0.6470.94
32_Y36_Q0.6460.94
324_V327_Q0.6460.94
150_A153_V0.6460.94
467_M470_E0.6450.94
377_R507_Y0.6430.94
220_L244_F0.6420.94
254_A257_M0.6410.94
437_L573_E0.6410.94
378_R385_S0.6400.94
44_S48_S0.6400.94
51_Q55_N0.6400.94
462_I466_E0.6370.94
244_F248_T0.6360.94
47_Q50_N0.6350.94
307_P311_L0.6340.94
347_F362_A0.6340.94
268_V278_A0.6330.93
382_A393_T0.6330.93
415_R418_M0.6320.93
19_V22_I0.6320.93
79_R83_D0.6320.93
402_L420_T0.6310.93
427_M434_L0.6310.93
458_M529_I0.6310.93
62_Q66_S0.6300.93
382_A430_L0.6300.93
381_V387_E0.6300.93
384_V394_T0.6290.93
523_E526_L0.6290.93
116_K123_F0.6290.93
115_G118_T0.6290.93
27_Q31_V0.6280.93
30_G34_V0.6270.93
377_R387_E0.6270.93
504_A531_V0.6260.93
270_A290_S0.6250.93
386_H389_R0.6250.93
549_R552_R0.6230.93
323_L360_L0.6230.93
380_F388_L0.6210.93
285_I362_A0.6200.93
210_L237_I0.6200.93
236_E240_L0.6200.93
392_L424_T0.6190.93
22_I25_A0.6190.93
397_S424_T0.6180.93
349_V357_I0.6170.93
63_E66_S0.6150.92
78_S82_N0.6140.92
278_A292_A0.6140.92
400_E421_Q0.6140.92
507_Y549_R0.6140.92
392_L401_A0.6140.92
509_P512_G0.6130.92
52_R57_S0.6120.92
396_R400_E0.6110.92
267_S272_M0.6100.92
308_I314_L0.6090.92
393_T428_I0.6080.92
147_L150_A0.6080.92
383_N427_M0.6080.92
279_T347_F0.6050.92
381_V507_Y0.6050.92
314_L318_Y0.6040.92
178_K182_T0.6030.92
390_T395_M0.6030.92
456_R460_L0.6020.92
412_I416_F0.6010.92
152_P160_V0.6000.92
400_E404_E0.6000.92
542_D545_K0.6000.92
435_L550_F0.6000.92
390_T401_A0.6000.92
380_F389_R0.5970.91
385_S435_L0.5960.91
181_N185_A0.5960.91
35_N39_K0.5960.91
34_V38_E0.5960.91
416_F420_T0.5950.91
163_A166_V0.5950.91
467_M502_S0.5940.91
492_K577_A0.5940.91
29_I32_Y0.5940.91
231_K242_T0.5920.91
268_V271_Y0.5920.91
122_I127_F0.5920.91
243_T247_L0.5900.91
542_D554_D0.5890.91
144_I169_S0.5880.91
13_K234_H0.5870.91
309_T313_G0.5870.91
241_A245_N0.5860.91
44_S47_Q0.5850.91
383_N398_Y0.5840.90
275_G361_I0.5830.90
596_F599_P0.5820.90
447_F574_M0.5820.90
313_G335_E0.5820.90
390_T564_T0.5800.90
391_P570_I0.5790.90
336_R339_E0.5790.90
415_R419_V0.5780.90
427_M435_L0.5780.90
437_L549_R0.5780.90
400_E403_A0.5780.90
47_Q51_Q0.5780.90
549_R553_V0.5770.90
389_R423_E0.5760.90
117_Q126_I0.5760.90
383_N401_A0.5760.90
459_S462_I0.5750.90
390_T435_L0.5750.90
308_I315_Q0.5750.90
168_A171_E0.5750.90
434_L550_F0.5750.90
410_K414_P0.5740.90
120_D123_F0.5730.90
52_R55_N0.5730.90
378_R383_N0.5720.90
120_D124_K0.5720.90
499_N571_A0.5720.90
268_V276_V0.5710.89
381_V389_R0.5700.89
377_R549_R0.5700.89
160_V164_I0.5700.89
117_Q121_L0.5690.89
455_V483_D0.5690.89
461_I465_F0.5690.89
230_K245_N0.5690.89
394_T416_F0.5670.89
11_Q204_R0.5660.89
116_K122_I0.5660.89
276_V289_N0.5660.89
387_E566_L0.5660.89
554_D561_L0.5660.89
397_S402_L0.5650.89
213_M237_I0.5650.89
335_E342_V0.5650.89
320_F323_L0.5650.89
255_Q258_T0.5640.89
384_V388_L0.5640.89
13_K205_T0.5640.89
55_N60_I0.5640.89
182_T185_A0.5640.89
210_L236_E0.5630.89
139_D150_A0.5630.89
388_L424_T0.5630.89
81_L93_I0.5620.89
549_R573_E0.5620.89
153_V160_V0.5620.89
42_I46_E0.5610.89
538_I584_A0.5600.89
124_K128_S0.5590.88
389_R437_L0.5590.88
377_R393_T0.5590.88
401_A435_L0.5590.88
543_V594_I0.5590.88
257_M260_G0.5580.88
550_F569_A0.5580.88
206_I237_I0.5570.88
473_V534_E0.5570.88
384_V549_R0.5550.88
85_T88_D0.5550.88
295_L343_L0.5550.88
380_F552_R0.5540.88
52_R56_L0.5530.88
146_V151_K0.5530.88
390_T566_L0.5520.88
394_T437_L0.5520.88
58_Y62_Q0.5510.88
170_M174_F0.5510.88
374_D377_R0.5500.88
462_I475_F0.5500.88
342_V350_I0.5490.88
479_L483_D0.5480.87
430_L434_L0.5480.87
152_P163_A0.5480.87
122_I130_K0.5480.87
177_M180_I0.5470.87
389_R506_K0.5460.87
240_L244_F0.5460.87
377_R382_A0.5440.87
278_A362_A0.5440.87
280_N305_E0.5430.87
277_I308_I0.5430.87
272_M423_E0.5420.87
378_R384_V0.5420.87
94_S100_Y0.5420.87
92_E102_V0.5410.87
342_V368_T0.5410.87
53_I166_V0.5410.87
292_A296_L0.5390.87
141_K148_I0.5390.87
530_S596_F0.5380.87
435_L489_D0.5380.87
389_R393_T0.5380.87
575_V578_H0.5370.86
458_M479_L0.5360.86
38_E42_I0.5360.86
380_F507_Y0.5360.86
327_Q330_M0.5350.86
240_L269_I0.5350.86
378_R549_R0.5340.86
216_Q247_L0.5340.86
101_E104_G0.5330.86
25_A29_I0.5320.86
100_Y104_G0.5320.86
285_I289_N0.5310.86
495_Q564_T0.5310.86
465_F502_S0.5300.86
384_V390_T0.5300.86
102_V105_S0.5290.86
276_V363_V0.5290.86
441_D507_Y0.5280.86
223_G248_T0.5270.85
102_V106_S0.5270.85
380_F386_H0.5270.85
492_K571_A0.5260.85
102_V108_P0.5260.85
162_G167_V0.5250.85
398_Y402_L0.5240.85
389_R398_Y0.5240.85
240_L251_L0.5240.85
396_R423_E0.5230.85
51_Q59_Y0.5230.85
289_N293_L0.5220.85
140_P144_I0.5220.85
540_K544_E0.5220.85
378_R427_M0.5220.85
173_V177_M0.5220.85
348_S361_I0.5210.85
30_G188_T0.5200.85
275_G279_T0.5200.85
40_S43_S0.5190.85
389_R552_R0.5180.84
209_P240_L0.5170.84
209_P225_F0.5170.84
214_R217_A0.5170.84
389_R507_Y0.5160.84
385_S397_S0.5160.84
533_D591_G0.5160.84
502_S552_R0.5160.84
493_I598_L0.5160.84
438_S570_I0.5160.84
329_S333_E0.5160.84
285_I303_A0.5150.84
45_Y48_S0.5140.84
346_N349_V0.5140.84
382_A495_Q0.5140.84
506_K562_G0.5130.84
397_S495_Q0.5130.84
499_N578_H0.5120.84
383_N393_T0.5120.84
383_N550_F0.5120.84
451_W488_I0.5110.84
102_V117_Q0.5110.84
471_Q510_E0.5110.84
268_V275_G0.5100.84
313_G317_N0.5090.83
241_A279_T0.5090.83
383_N400_E0.5080.83
392_L427_M0.5080.83
555_K562_G0.5070.83
426_R494_T0.5070.83
163_A167_V0.5050.83
77_V80_I0.5050.83
374_D378_R0.5050.83
385_S433_D0.5050.83
165_Y170_M0.5050.83
320_F325_E0.5040.83
516_F529_I0.5040.83
378_R495_Q0.5040.83
484_L600_Y0.5030.83
386_H395_M0.5030.83
223_G247_L0.5020.83
455_V481_D0.5020.83
433_D495_Q0.5010.82
562_G570_I0.5010.82
275_G366_D0.5000.82
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4i5sA 2 0.6399 100 0.361 Contact Map
4gczA 2 0.5679 100 0.494 Contact Map
3a0rA 2 0.5254 100 0.495 Contact Map
4r3aA 1 0.5008 100 0.575 Contact Map
4bixA 2 0.3732 100 0.586 Contact Map
4ctiA 2 0.3732 100 0.607 Contact Map
4q20A 2 0.3764 100 0.627 Contact Map
3jz3A 2 0.2635 100 0.627 Contact Map
2c2aA 2 0.3732 100 0.628 Contact Map
4mpcA 2 0.5057 100 0.63 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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