YYCG - BACSU - GREMLIN Contacts

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YYCG - Sensor histidine kinase YycG

UniProt:	Q45614	Sequences: MNKVGFFRSIQFKITLIYVLLIIIAMQIIGVYFVNQVEKSLISSYEQSLNQRIDNLSYYIEQEYKSDNDSTVIKDDVSRILNDFTKSDEVREISFVDKSYEVVGSSKPYGEEVAGKQTTDLIFKRIFSTKQSYLRKYYDPKSKIRVLISAKPVMTENQEVVGAIYVVASMEDVFNQMKTINTILASGTGLALVLTALLGIFLARTITHPLSDMRKQAMELAKGNFSRKVKKYGHDEIGQLATTFNHLTRELEDAQAMTEGERRKLASVIAYMTDGVIATNRNGAIILLNSPALELLNVSRETALEMPITSLLGLQENYTFEDLVEQQDSMLLEIERDDELTVLRVNFSVIQREHGKIDGLIAVIYDVTEQEKMDQERREFVANVSHELRTPLTTMRSYLEALAEGAWENKDIAPRFLMVTQNETERMIRLVNDLLQLSKFDSKDYQFNREWIQIVRFMSLIIDRFEMTKEQHVEFIRNLPDRDLYVEIDQDKITQVLDNIISNALKYSPEGGHVTFSIDVNEEEELLYISVKDEGIGIPKKDVEKVFDRFYRVDKARTRKLGGTGLGLAIAKEMVQAHGGDIWADSIEGKGTTITFTLPYKEEQEDDWDEA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	611 (572)
Sequences:	5771 (5098)
Seq/√Len:	213.1

ECOLI - ATOS BARA DCUS RCSD NARX DPIB RCSC NARQ ARCB TORS PHOR EVGS CUSS CREC GLRK BAES PHOQ QSEC CPXA YEDV ZRAS ENVZ NTRB RSTB
BACSU - YYCG RESE PHOR DCTS CITS MALK KINE KINC KINA YCLK YVRG YKOH CSSS KIND
HALSA - Q9HQ16 Q9HQG5 O51970 Q9HR10 Q9HRE4 Q9HRG1 Q9HNM2 BAT

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
587_I	590_K	5.383	1.00
532_K	593_T	4.759	1.00
219_E	224_N	4.669	1.00
399_L	420_T	4.627	1.00
235_D	238_G	4.103	1.00
371_E	374_D	3.983	1.00
508_S	534_E	3.934	1.00
274_D	365_Y	3.869	1.00
543_V	584_A	3.670	1.00
280_N	284_A	3.629	1.00
478_N	517_S	3.570	1.00
496_V	574_M	3.373	1.00
584_A	594_I	3.326	1.00
529_I	596_F	3.247	1.00
496_V	575_V	3.182	1.00
233_G	238_G	3.113	1.00
583_W	595_T	3.057	1.00
476_I	513_H	3.023	1.00
452_I	488_I	2.997	1.00
575_V	596_F	2.995	1.00
371_E	375_Q	2.959	1.00
572_K	576_Q	2.932	1.00
515_T	532_K	2.912	1.00
517_S	530_S	2.907	1.00
262_R	266_A	2.868	1.00
571_A	582_I	2.820	1.00
13_K	235_D	2.800	1.00
513_H	534_E	2.798	1.00
488_I	578_H	2.696	1.00
476_I	515_T	2.599	1.00
453_Q	456_R	2.590	1.00
517_S	532_K	2.581	1.00
575_V	580_G	2.580	1.00
530_S	593_T	2.536	1.00
228_K	245_N	2.527	1.00
526_L	597_T	2.483	1.00
306_M	310_S	2.455	1.00
403_A	418_M	2.445	1.00
574_M	578_H	2.420	1.00
488_I	493_I	2.417	1.00
586_S	592_T	2.387	1.00
228_K	252_E	2.386	1.00
585_D	593_T	2.354	1.00
538_I	542_D	2.354	1.00
261_E	264_K	2.333	1.00
220_L	248_T	2.323	1.00
277_I	292_A	2.283	1.00
586_S	589_G	2.273	1.00
508_S	512_G	2.273	1.00
455_V	518_I	2.272	1.00
530_S	595_T	2.267	1.00
450_E	490_Q	2.263	1.00
507_Y	552_R	2.257	1.00
586_S	590_K	2.199	1.00
474_E	513_H	2.180	1.00
528_Y	597_T	2.167	1.00
533_D	537_G	2.163	1.00
217_A	247_L	2.136	1.00
478_N	515_T	2.074	1.00
466_E	469_K	2.073	1.00
451_W	487_E	2.072	1.00
244_F	247_L	2.069	1.00
97_D	101_E	2.059	1.00
226_S	252_E	2.036	1.00
373_M	376_E	2.028	1.00
275_G	295_L	1.985	1.00
290_S	294_E	1.974	1.00
228_K	248_T	1.939	1.00
492_K	495_Q	1.927	1.00
277_I	285_I	1.919	1.00
502_S	506_K	1.877	1.00
580_G	598_L	1.861	1.00
277_I	362_A	1.853	1.00
259_E	262_R	1.851	1.00
528_Y	595_T	1.847	1.00
497_L	529_I	1.837	1.00
527_L	600_Y	1.820	1.00
382_A	387_E	1.820	1.00
403_A	414_P	1.809	1.00
213_M	244_F	1.797	1.00
199_G	203_A	1.784	1.00
539_P	542_D	1.777	1.00
162_G	169_S	1.767	1.00
322_D	326_Q	1.749	1.00
581_D	597_T	1.747	1.00
220_L	247_L	1.743	1.00
547_F	582_I	1.737	1.00
508_S	514_V	1.733	1.00
403_A	421_Q	1.722	1.00
369_E	372_K	1.720	1.00
479_L	518_I	1.713	1.00
396_R	425_E	1.706	1.00
489_D	492_K	1.698	1.00
275_G	364_I	1.696	1.00
515_T	534_E	1.692	1.00
496_V	571_A	1.689	1.00
372_K	376_E	1.679	1.00
460_L	494_T	1.666	1.00
247_L	251_L	1.664	1.00
540_K	587_I	1.662	1.00
370_Q	374_D	1.662	1.00
576_Q	581_D	1.658	1.00
291_P	294_E	1.658	1.00
272_M	276_V	1.651	1.00
465_F	498_D	1.649	1.00
545_K	548_D	1.645	1.00
262_R	265_L	1.633	1.00
504_A	514_V	1.624	1.00
492_K	574_M	1.612	1.00
396_R	424_T	1.598	1.00
372_K	375_Q	1.597	1.00
539_P	588_E	1.593	1.00
538_I	546_V	1.584	1.00
429_R	491_D	1.582	1.00
543_V	586_S	1.575	1.00
402_L	413_A	1.547	1.00
217_A	244_F	1.541	1.00
266_A	270_A	1.537	1.00
497_L	531_V	1.535	1.00
546_V	584_A	1.533	1.00
228_K	249_R	1.508	1.00
453_Q	483_D	1.508	1.00
585_D	595_T	1.506	1.00
344_R	370_Q	1.477	1.00
398_Y	416_F	1.470	1.00
395_M	420_T	1.469	1.00
387_E	390_T	1.448	1.00
526_L	581_D	1.447	1.00
234_H	238_G	1.442	1.00
455_V	479_L	1.442	1.00
453_Q	485_Y	1.439	1.00
493_I	578_H	1.431	1.00
152_P	162_G	1.431	1.00
248_T	251_L	1.428	1.00
352_R	356_K	1.417	1.00
458_M	497_L	1.411	1.00
49_L	53_I	1.404	1.00
454_I	529_I	1.392	1.00
217_A	240_L	1.387	1.00
451_W	485_Y	1.386	1.00
496_V	578_H	1.382	1.00
538_I	592_T	1.371	1.00
206_I	209_P	1.364	1.00
523_E	528_Y	1.361	1.00
313_G	316_E	1.359	1.00
455_V	459_S	1.357	1.00
387_E	391_P	1.351	1.00
394_T	423_E	1.349	1.00
265_L	269_I	1.347	1.00
584_A	592_T	1.345	1.00
583_W	597_T	1.344	1.00
399_L	417_L	1.344	1.00
307_P	310_S	1.340	1.00
497_L	501_I	1.339	1.00
468_T	514_V	1.334	1.00
547_F	594_I	1.330	1.00
377_R	381_V	1.326	1.00
458_M	518_I	1.323	1.00
92_E	105_S	1.320	1.00
269_I	289_N	1.312	1.00
125_R	129_T	1.288	1.00
96_V	102_V	1.287	1.00
344_R	365_Y	1.285	1.00
461_I	494_T	1.285	1.00
410_K	413_A	1.279	1.00
245_N	248_T	1.272	1.00
278_A	359_G	1.269	1.00
261_E	265_L	1.268	1.00
575_V	598_L	1.267	1.00
288_L	292_A	1.266	1.00
500_I	531_V	1.261	1.00
399_L	424_T	1.260	1.00
500_I	571_A	1.259	1.00
540_K	543_V	1.254	1.00
217_A	243_T	1.252	1.00
117_Q	120_D	1.251	1.00
116_K	120_D	1.245	1.00
387_E	570_I	1.240	1.00
465_F	505_L	1.239	1.00
495_Q	574_M	1.224	1.00
216_Q	229_V	1.219	1.00
9_S	12_F	1.219	1.00
298_V	302_T	1.219	1.00
548_D	551_Y	1.215	1.00
512_G	534_E	1.215	1.00
269_I	287_L	1.215	1.00
251_L	254_A	1.213	1.00
460_L	490_Q	1.204	1.00
506_K	554_D	1.200	1.00
371_E	376_E	1.199	1.00
461_I	501_I	1.195	1.00
497_L	596_F	1.195	1.00
385_S	390_T	1.190	1.00
380_F	383_N	1.189	1.00
423_E	426_R	1.186	1.00
122_I	126_I	1.186	1.00
148_I	151_K	1.179	1.00
459_S	477_R	1.178	1.00
299_S	302_T	1.178	1.00
397_S	401_A	1.169	1.00
117_Q	122_I	1.161	1.00
389_R	427_M	1.159	1.00
547_F	584_A	1.159	1.00
398_Y	419_V	1.158	1.00
554_D	562_G	1.157	1.00
546_V	594_I	1.156	1.00
454_I	527_L	1.153	1.00
254_A	258_T	1.148	1.00
462_I	477_R	1.147	1.00
458_M	516_F	1.143	1.00
275_G	289_N	1.140	1.00
449_R	487_E	1.136	1.00
29_I	33_F	1.133	1.00
384_V	434_L	1.129	1.00
522_E	600_Y	1.129	1.00
518_I	529_I	1.119	1.00
418_M	422_N	1.116	1.00
218_M	239_Q	1.108	1.00
123_F	126_I	1.107	1.00
500_I	594_I	1.105	1.00
390_T	397_S	1.103	1.00
162_G	166_V	1.103	1.00
449_R	578_H	1.093	1.00
434_L	438_S	1.093	1.00
279_T	285_I	1.093	1.00
388_L	391_P	1.090	1.00
542_D	553_V	1.088	1.00
399_L	421_Q	1.088	1.00
139_D	142_S	1.088	1.00
428_I	432_N	1.085	1.00
402_L	417_L	1.083	1.00
383_N	549_R	1.078	1.00
538_I	568_L	1.075	1.00
468_T	505_L	1.074	1.00
288_L	293_L	1.069	1.00
293_L	300_R	1.066	1.00
298_V	336_R	1.062	1.00
500_I	596_F	1.061	1.00
253_D	257_M	1.058	1.00
277_I	289_N	1.057	1.00
165_Y	169_S	1.054	1.00
214_R	239_Q	1.050	1.00
327_Q	333_E	1.050	1.00
57_S	61_E	1.049	1.00
229_V	241_A	1.043	1.00
321_E	325_E	1.042	1.00
458_M	477_R	1.041	1.00
406_A	413_A	1.038	1.00
204_R	208_H	1.038	1.00
213_M	217_A	1.036	1.00
388_L	427_M	1.036	1.00
225_F	251_L	1.030	1.00
496_V	596_F	1.024	1.00
250_E	253_D	1.023	1.00
486_V	598_L	1.022	1.00
119_T	122_I	1.021	1.00
380_F	385_S	1.021	1.00
433_D	564_T	1.020	1.00
259_E	263_R	1.018	1.00
121_L	125_R	1.018	1.00
293_L	299_S	1.015	1.00
218_M	222_K	1.014	1.00
457_F	461_I	1.007	1.00
552_R	561_L	1.007	1.00
514_V	518_I	1.006	1.00
464_R	498_D	1.005	1.00
475_F	514_V	1.004	1.00
583_W	596_F	1.004	1.00
290_S	293_L	1.001	1.00
575_V	582_I	0.996	1.00
381_V	390_T	0.996	1.00
53_I	57_S	0.994	1.00
293_L	303_A	0.993	1.00
386_H	390_T	0.992	1.00
10_I	206_I	0.989	1.00
269_I	276_V	0.988	1.00
116_K	119_T	0.987	1.00
289_N	368_T	0.983	1.00
521_N	528_Y	0.980	1.00
435_L	564_T	0.979	1.00
390_T	394_T	0.979	1.00
260_G	264_K	0.978	1.00
493_I	596_F	0.977	1.00
538_I	543_V	0.975	1.00
255_Q	259_E	0.974	1.00
421_Q	425_E	0.972	1.00
508_S	511_G	0.970	1.00
506_K	552_R	0.970	1.00
229_V	245_N	0.969	1.00
333_E	371_E	0.969	1.00
46_E	50_N	0.968	1.00
258_T	261_E	0.968	1.00
387_E	495_Q	0.967	1.00
383_N	389_R	0.960	1.00
216_Q	244_F	0.959	1.00
349_V	359_G	0.953	1.00
447_F	578_H	0.952	1.00
216_Q	227_R	0.952	1.00
65_K	68_N	0.949	1.00
251_L	255_Q	0.946	1.00
50_N	54_D	0.943	0.99
377_R	383_N	0.943	0.99
45_Y	49_L	0.938	0.99
435_L	439_K	0.933	0.99
261_E	266_A	0.929	0.99
388_L	431_V	0.928	0.99
542_D	551_Y	0.928	0.99
124_K	127_F	0.924	0.99
447_F	492_K	0.924	0.99
382_A	385_S	0.923	0.99
203_A	207_T	0.919	0.99
289_N	366_D	0.919	0.99
521_N	524_E	0.915	0.99
394_T	398_Y	0.909	0.99
102_V	107_K	0.907	0.99
278_A	287_L	0.906	0.99
394_T	419_V	0.906	0.99
278_A	289_N	0.905	0.99
452_I	493_I	0.904	0.99
398_Y	552_R	0.902	0.99
279_T	362_A	0.901	0.99
381_V	393_T	0.900	0.99
457_F	488_I	0.897	0.99
391_P	427_M	0.897	0.99
278_A	361_I	0.894	0.99
84_F	88_D	0.893	0.99
419_V	423_E	0.892	0.99
472_H	510_E	0.889	0.99
149_S	152_P	0.888	0.99
159_E	162_G	0.887	0.99
398_Y	420_T	0.886	0.99
213_M	241_A	0.886	0.99
501_I	516_F	0.882	0.99
386_H	391_P	0.880	0.99
345_V	364_I	0.874	0.99
393_T	396_R	0.873	0.99
217_A	221_A	0.871	0.99
390_T	393_T	0.871	0.99
176_Q	180_I	0.870	0.99
382_A	388_L	0.868	0.99
423_E	435_L	0.866	0.99
319_T	322_D	0.865	0.99
258_T	262_R	0.864	0.99
385_S	389_R	0.864	0.99
396_R	428_I	0.864	0.99
566_L	570_I	0.863	0.99
378_R	382_A	0.862	0.99
41_L	44_S	0.862	0.99
379_E	383_N	0.861	0.99
224_N	227_R	0.860	0.99
79_R	82_N	0.859	0.99
129_T	132_S	0.859	0.99
456_R	490_Q	0.856	0.99
525_E	600_Y	0.856	0.99
459_S	463_D	0.856	0.99
154_M	162_G	0.854	0.99
183_I	186_S	0.854	0.99
530_S	585_D	0.851	0.99
447_F	489_D	0.849	0.99
399_L	403_A	0.846	0.99
383_N	437_L	0.845	0.99
389_R	428_I	0.843	0.99
149_S	154_M	0.843	0.99
92_E	167_V	0.842	0.99
445_Y	492_K	0.840	0.99
377_R	385_S	0.837	0.99
380_F	435_L	0.835	0.99
387_E	430_L	0.834	0.99
545_K	551_Y	0.833	0.99
164_I	169_S	0.833	0.99
420_T	424_T	0.831	0.99
383_N	387_E	0.830	0.99
435_L	438_S	0.829	0.99
483_D	518_I	0.828	0.99
330_M	333_E	0.827	0.99
35_N	38_E	0.826	0.99
414_P	418_M	0.826	0.99
388_L	398_Y	0.822	0.99
53_I	56_L	0.819	0.99
536_I	592_T	0.817	0.99
536_I	561_L	0.816	0.99
269_I	275_G	0.815	0.99
380_F	390_T	0.814	0.99
508_S	552_R	0.813	0.99
63_E	67_D	0.810	0.98
447_F	577_A	0.809	0.98
84_F	87_S	0.806	0.98
31_V	35_N	0.804	0.98
538_I	594_I	0.803	0.98
424_T	427_M	0.801	0.98
521_N	530_S	0.800	0.98
385_S	507_Y	0.798	0.98
472_H	511_G	0.797	0.98
142_S	146_V	0.796	0.98
58_Y	61_E	0.795	0.98
383_N	390_T	0.795	0.98
426_R	430_L	0.794	0.98
506_K	553_V	0.794	0.98
320_F	324_V	0.793	0.98
285_I	288_L	0.793	0.98
178_K	181_N	0.789	0.98
94_S	102_V	0.789	0.98
342_V	367_V	0.783	0.98
33_F	37_V	0.781	0.98
184_L	187_G	0.780	0.98
169_S	172_D	0.778	0.98
407_W	413_A	0.778	0.98
162_G	170_M	0.777	0.98
490_Q	494_T	0.776	0.98
297_N	338_D	0.776	0.98
507_Y	554_D	0.775	0.98
284_A	307_P	0.775	0.98
580_G	599_P	0.774	0.98
380_F	384_V	0.773	0.98
195_T	199_G	0.773	0.98
395_M	424_T	0.773	0.98
495_Q	570_I	0.771	0.98
389_R	435_L	0.769	0.98
396_R	399_L	0.768	0.98
302_T	336_R	0.768	0.98
264_K	268_V	0.767	0.98
77_V	84_F	0.766	0.98
236_E	247_L	0.765	0.98
64_Y	68_N	0.763	0.98
378_R	441_D	0.761	0.98
275_G	292_A	0.760	0.98
323_L	326_Q	0.760	0.98
77_V	104_G	0.759	0.98
586_S	593_T	0.757	0.98
162_G	165_Y	0.756	0.98
51_Q	54_D	0.755	0.98
341_T	366_D	0.754	0.98
379_E	387_E	0.754	0.98
347_F	360_L	0.750	0.97
377_R	390_T	0.749	0.97
549_R	554_D	0.749	0.97
119_T	123_F	0.749	0.97
257_M	261_E	0.748	0.97
506_K	561_L	0.746	0.97
449_R	488_I	0.745	0.97
139_D	146_V	0.745	0.97
162_G	168_A	0.745	0.97
465_F	501_I	0.745	0.97
536_I	586_S	0.742	0.97
185_A	189_G	0.741	0.97
550_F	566_L	0.741	0.97
393_T	397_S	0.741	0.97
214_R	218_M	0.740	0.97
240_L	247_L	0.740	0.97
468_T	475_F	0.738	0.97
389_R	432_N	0.738	0.97
386_H	499_N	0.737	0.97
398_Y	423_E	0.736	0.97
94_S	105_S	0.736	0.97
382_A	391_P	0.736	0.97
147_L	151_K	0.733	0.97
269_I	278_A	0.733	0.97
115_G	119_T	0.733	0.97
275_G	296_L	0.731	0.97
381_V	384_V	0.731	0.97
422_N	460_L	0.729	0.97
439_K	445_Y	0.729	0.97
367_V	371_E	0.727	0.97
437_L	441_D	0.726	0.97
264_K	287_L	0.726	0.97
214_R	243_T	0.726	0.97
385_S	506_K	0.726	0.97
377_R	389_R	0.723	0.97
285_I	292_A	0.723	0.97
501_I	514_V	0.720	0.97
507_Y	536_I	0.720	0.97
384_V	393_T	0.719	0.97
377_R	384_V	0.719	0.97
423_E	434_L	0.719	0.97
508_S	536_I	0.717	0.97
225_F	247_L	0.716	0.97
279_T	308_I	0.716	0.97
139_D	148_I	0.716	0.97
434_L	439_K	0.715	0.97
288_L	303_A	0.715	0.97
283_G	289_N	0.715	0.97
289_N	292_A	0.715	0.97
209_P	235_D	0.714	0.97
146_V	149_S	0.712	0.97
387_E	571_A	0.711	0.97
516_F	531_V	0.710	0.96
218_M	246_H	0.709	0.96
435_L	506_K	0.709	0.96
390_T	570_I	0.708	0.96
220_L	223_G	0.707	0.96
265_L	268_V	0.707	0.96
255_Q	262_R	0.705	0.96
231_K	245_N	0.705	0.96
507_Y	561_L	0.705	0.96
367_V	370_Q	0.704	0.96
286_I	359_G	0.703	0.96
390_T	507_Y	0.700	0.96
182_T	186_S	0.700	0.96
494_T	498_D	0.700	0.96
383_N	388_L	0.698	0.96
377_R	441_D	0.697	0.96
278_A	350_I	0.697	0.96
408_E	413_A	0.696	0.96
150_A	163_A	0.696	0.96
377_R	506_K	0.695	0.96
523_E	597_T	0.694	0.96
389_R	495_Q	0.693	0.96
264_K	278_A	0.693	0.96
341_T	368_T	0.693	0.96
380_F	502_S	0.692	0.96
149_S	153_V	0.691	0.96
538_I	586_S	0.690	0.96
48_S	51_Q	0.690	0.96
507_Y	553_V	0.689	0.96
377_R	552_R	0.689	0.96
473_V	505_L	0.689	0.96
246_H	250_E	0.689	0.96
80_I	83_D	0.688	0.96
57_S	60_I	0.688	0.96
351_Q	357_I	0.688	0.96
77_V	81_L	0.686	0.96
382_A	566_L	0.686	0.96
55_N	59_Y	0.686	0.96
388_L	430_L	0.683	0.96
387_E	393_T	0.682	0.96
499_N	564_T	0.682	0.96
480_P	483_D	0.682	0.96
492_K	496_V	0.679	0.95
148_I	167_V	0.679	0.95
151_K	154_M	0.679	0.95
131_Q	135_R	0.679	0.95
493_I	497_L	0.679	0.95
54_D	58_Y	0.678	0.95
268_V	289_N	0.678	0.95
507_Y	551_Y	0.677	0.95
468_T	473_V	0.677	0.95
382_A	389_R	0.676	0.95
76_D	80_I	0.676	0.95
114_A	117_Q	0.675	0.95
143_K	152_P	0.672	0.95
220_L	225_F	0.672	0.95
219_E	227_R	0.671	0.95
437_L	507_Y	0.670	0.95
312_L	317_N	0.669	0.95
97_D	100_Y	0.669	0.95
92_E	106_S	0.668	0.95
452_I	457_F	0.668	0.95
415_R	463_D	0.668	0.95
60_I	63_E	0.667	0.95
427_M	436_Q	0.666	0.95
502_S	564_T	0.665	0.95
209_P	236_E	0.664	0.95
387_E	427_M	0.664	0.95
163_A	169_S	0.663	0.95
381_V	392_L	0.661	0.95
216_Q	223_G	0.660	0.95
387_E	423_E	0.660	0.95
146_V	167_V	0.659	0.95
484_L	527_L	0.658	0.95
449_R	579_G	0.657	0.95
539_P	553_V	0.657	0.95
389_R	433_D	0.656	0.95
252_E	256_A	0.655	0.95
382_A	390_T	0.655	0.95
484_L	518_I	0.655	0.95
493_I	575_V	0.655	0.95
377_R	380_F	0.654	0.94
121_L	124_K	0.653	0.94
383_N	554_D	0.653	0.94
416_F	549_R	0.652	0.94
393_T	566_L	0.651	0.94
56_L	59_Y	0.651	0.94
405_G	413_A	0.650	0.94
256_A	260_G	0.650	0.94
383_N	572_K	0.649	0.94
486_V	527_L	0.648	0.94
123_F	127_F	0.648	0.94
393_T	423_E	0.647	0.94
424_T	428_I	0.647	0.94
32_Y	36_Q	0.646	0.94
324_V	327_Q	0.646	0.94
150_A	153_V	0.646	0.94
467_M	470_E	0.645	0.94
377_R	507_Y	0.643	0.94
220_L	244_F	0.642	0.94
254_A	257_M	0.641	0.94
437_L	573_E	0.641	0.94
378_R	385_S	0.640	0.94
44_S	48_S	0.640	0.94
51_Q	55_N	0.640	0.94
462_I	466_E	0.637	0.94
244_F	248_T	0.636	0.94
47_Q	50_N	0.635	0.94
307_P	311_L	0.634	0.94
347_F	362_A	0.634	0.94
268_V	278_A	0.633	0.93
382_A	393_T	0.633	0.93
415_R	418_M	0.632	0.93
19_V	22_I	0.632	0.93
79_R	83_D	0.632	0.93
402_L	420_T	0.631	0.93
427_M	434_L	0.631	0.93
458_M	529_I	0.631	0.93
62_Q	66_S	0.630	0.93
382_A	430_L	0.630	0.93
381_V	387_E	0.630	0.93
384_V	394_T	0.629	0.93
523_E	526_L	0.629	0.93
116_K	123_F	0.629	0.93
115_G	118_T	0.629	0.93
27_Q	31_V	0.628	0.93
30_G	34_V	0.627	0.93
377_R	387_E	0.627	0.93
504_A	531_V	0.626	0.93
270_A	290_S	0.625	0.93
386_H	389_R	0.625	0.93
549_R	552_R	0.623	0.93
323_L	360_L	0.623	0.93
380_F	388_L	0.621	0.93
285_I	362_A	0.620	0.93
210_L	237_I	0.620	0.93
236_E	240_L	0.620	0.93
392_L	424_T	0.619	0.93
22_I	25_A	0.619	0.93
397_S	424_T	0.618	0.93
349_V	357_I	0.617	0.93
63_E	66_S	0.615	0.92
78_S	82_N	0.614	0.92
278_A	292_A	0.614	0.92
400_E	421_Q	0.614	0.92
507_Y	549_R	0.614	0.92
392_L	401_A	0.614	0.92
509_P	512_G	0.613	0.92
52_R	57_S	0.612	0.92
396_R	400_E	0.611	0.92
267_S	272_M	0.610	0.92
308_I	314_L	0.609	0.92
393_T	428_I	0.608	0.92
147_L	150_A	0.608	0.92
383_N	427_M	0.608	0.92
279_T	347_F	0.605	0.92
381_V	507_Y	0.605	0.92
314_L	318_Y	0.604	0.92
178_K	182_T	0.603	0.92
390_T	395_M	0.603	0.92
456_R	460_L	0.602	0.92
412_I	416_F	0.601	0.92
152_P	160_V	0.600	0.92
400_E	404_E	0.600	0.92
542_D	545_K	0.600	0.92
435_L	550_F	0.600	0.92
390_T	401_A	0.600	0.92
380_F	389_R	0.597	0.91
385_S	435_L	0.596	0.91
181_N	185_A	0.596	0.91
35_N	39_K	0.596	0.91
34_V	38_E	0.596	0.91
416_F	420_T	0.595	0.91
163_A	166_V	0.595	0.91
467_M	502_S	0.594	0.91
492_K	577_A	0.594	0.91
29_I	32_Y	0.594	0.91
231_K	242_T	0.592	0.91
268_V	271_Y	0.592	0.91
122_I	127_F	0.592	0.91
243_T	247_L	0.590	0.91
542_D	554_D	0.589	0.91
144_I	169_S	0.588	0.91
13_K	234_H	0.587	0.91
309_T	313_G	0.587	0.91
241_A	245_N	0.586	0.91
44_S	47_Q	0.585	0.91
383_N	398_Y	0.584	0.90
275_G	361_I	0.583	0.90
596_F	599_P	0.582	0.90
447_F	574_M	0.582	0.90
313_G	335_E	0.582	0.90
390_T	564_T	0.580	0.90
391_P	570_I	0.579	0.90
336_R	339_E	0.579	0.90
415_R	419_V	0.578	0.90
427_M	435_L	0.578	0.90
437_L	549_R	0.578	0.90
400_E	403_A	0.578	0.90
47_Q	51_Q	0.578	0.90
549_R	553_V	0.577	0.90
389_R	423_E	0.576	0.90
117_Q	126_I	0.576	0.90
383_N	401_A	0.576	0.90
459_S	462_I	0.575	0.90
390_T	435_L	0.575	0.90
308_I	315_Q	0.575	0.90
168_A	171_E	0.575	0.90
434_L	550_F	0.575	0.90
410_K	414_P	0.574	0.90
120_D	123_F	0.573	0.90
52_R	55_N	0.573	0.90
378_R	383_N	0.572	0.90
120_D	124_K	0.572	0.90
499_N	571_A	0.572	0.90
268_V	276_V	0.571	0.89
381_V	389_R	0.570	0.89
377_R	549_R	0.570	0.89
160_V	164_I	0.570	0.89
117_Q	121_L	0.569	0.89
455_V	483_D	0.569	0.89
461_I	465_F	0.569	0.89
230_K	245_N	0.569	0.89
394_T	416_F	0.567	0.89
11_Q	204_R	0.566	0.89
116_K	122_I	0.566	0.89
276_V	289_N	0.566	0.89
387_E	566_L	0.566	0.89
554_D	561_L	0.566	0.89
397_S	402_L	0.565	0.89
213_M	237_I	0.565	0.89
335_E	342_V	0.565	0.89
320_F	323_L	0.565	0.89
255_Q	258_T	0.564	0.89
384_V	388_L	0.564	0.89
13_K	205_T	0.564	0.89
55_N	60_I	0.564	0.89
182_T	185_A	0.564	0.89
210_L	236_E	0.563	0.89
139_D	150_A	0.563	0.89
388_L	424_T	0.563	0.89
81_L	93_I	0.562	0.89
549_R	573_E	0.562	0.89
153_V	160_V	0.562	0.89
42_I	46_E	0.561	0.89
538_I	584_A	0.560	0.89
124_K	128_S	0.559	0.88
389_R	437_L	0.559	0.88
377_R	393_T	0.559	0.88
401_A	435_L	0.559	0.88
543_V	594_I	0.559	0.88
257_M	260_G	0.558	0.88
550_F	569_A	0.558	0.88
206_I	237_I	0.557	0.88
473_V	534_E	0.557	0.88
384_V	549_R	0.555	0.88
85_T	88_D	0.555	0.88
295_L	343_L	0.555	0.88
380_F	552_R	0.554	0.88
52_R	56_L	0.553	0.88
146_V	151_K	0.553	0.88
390_T	566_L	0.552	0.88
394_T	437_L	0.552	0.88
58_Y	62_Q	0.551	0.88
170_M	174_F	0.551	0.88
374_D	377_R	0.550	0.88
462_I	475_F	0.550	0.88
342_V	350_I	0.549	0.88
479_L	483_D	0.548	0.87
430_L	434_L	0.548	0.87
152_P	163_A	0.548	0.87
122_I	130_K	0.548	0.87
177_M	180_I	0.547	0.87
389_R	506_K	0.546	0.87
240_L	244_F	0.546	0.87
377_R	382_A	0.544	0.87
278_A	362_A	0.544	0.87
280_N	305_E	0.543	0.87
277_I	308_I	0.543	0.87
272_M	423_E	0.542	0.87
378_R	384_V	0.542	0.87
94_S	100_Y	0.542	0.87
92_E	102_V	0.541	0.87
342_V	368_T	0.541	0.87
53_I	166_V	0.541	0.87
292_A	296_L	0.539	0.87
141_K	148_I	0.539	0.87
530_S	596_F	0.538	0.87
435_L	489_D	0.538	0.87
389_R	393_T	0.538	0.87
575_V	578_H	0.537	0.86
458_M	479_L	0.536	0.86
38_E	42_I	0.536	0.86
380_F	507_Y	0.536	0.86
327_Q	330_M	0.535	0.86
240_L	269_I	0.535	0.86
378_R	549_R	0.534	0.86
216_Q	247_L	0.534	0.86
101_E	104_G	0.533	0.86
25_A	29_I	0.532	0.86
100_Y	104_G	0.532	0.86
285_I	289_N	0.531	0.86
495_Q	564_T	0.531	0.86
465_F	502_S	0.530	0.86
384_V	390_T	0.530	0.86
102_V	105_S	0.529	0.86
276_V	363_V	0.529	0.86
441_D	507_Y	0.528	0.86
223_G	248_T	0.527	0.85
102_V	106_S	0.527	0.85
380_F	386_H	0.527	0.85
492_K	571_A	0.526	0.85
102_V	108_P	0.526	0.85
162_G	167_V	0.525	0.85
398_Y	402_L	0.524	0.85
389_R	398_Y	0.524	0.85
240_L	251_L	0.524	0.85
396_R	423_E	0.523	0.85
51_Q	59_Y	0.523	0.85
289_N	293_L	0.522	0.85
140_P	144_I	0.522	0.85
540_K	544_E	0.522	0.85
378_R	427_M	0.522	0.85
173_V	177_M	0.522	0.85
348_S	361_I	0.521	0.85
30_G	188_T	0.520	0.85
275_G	279_T	0.520	0.85
40_S	43_S	0.519	0.85
389_R	552_R	0.518	0.84
209_P	240_L	0.517	0.84
209_P	225_F	0.517	0.84
214_R	217_A	0.517	0.84
389_R	507_Y	0.516	0.84
385_S	397_S	0.516	0.84
533_D	591_G	0.516	0.84
502_S	552_R	0.516	0.84
493_I	598_L	0.516	0.84
438_S	570_I	0.516	0.84
329_S	333_E	0.516	0.84
285_I	303_A	0.515	0.84
45_Y	48_S	0.514	0.84
346_N	349_V	0.514	0.84
382_A	495_Q	0.514	0.84
506_K	562_G	0.513	0.84
397_S	495_Q	0.513	0.84
499_N	578_H	0.512	0.84
383_N	393_T	0.512	0.84
383_N	550_F	0.512	0.84
451_W	488_I	0.511	0.84
102_V	117_Q	0.511	0.84
471_Q	510_E	0.511	0.84
268_V	275_G	0.510	0.84
313_G	317_N	0.509	0.83
241_A	279_T	0.509	0.83
383_N	400_E	0.508	0.83
392_L	427_M	0.508	0.83
555_K	562_G	0.507	0.83
426_R	494_T	0.507	0.83
163_A	167_V	0.505	0.83
77_V	80_I	0.505	0.83
374_D	378_R	0.505	0.83
385_S	433_D	0.505	0.83
165_Y	170_M	0.505	0.83
320_F	325_E	0.504	0.83
516_F	529_I	0.504	0.83
378_R	495_Q	0.504	0.83
484_L	600_Y	0.503	0.83
386_H	395_M	0.503	0.83
223_G	247_L	0.502	0.83
455_V	481_D	0.502	0.83
433_D	495_Q	0.501	0.82
562_G	570_I	0.501	0.82
275_G	366_D	0.500	0.82

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.6399	100	0.361	Contact Map
4gczA	2	0.5679	100	0.494	Contact Map
3a0rA	2	0.5254	100	0.495	Contact Map
4r3aA	1	0.5008	100	0.575	Contact Map
4bixA	2	0.3732	100	0.586	Contact Map
4ctiA	2	0.3732	100	0.607	Contact Map
4q20A	2	0.3764	100	0.627	Contact Map
3jz3A	2	0.2635	100	0.627	Contact Map
2c2aA	2	0.3732	100	0.628	Contact Map
4mpcA	2	0.5057	100	0.63	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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