GREMLIN Database
F16PC - Fructose-1,6-bisphosphatase class 3
UniProt: Q45597 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 641 (631)
Sequences: 569 (376)
Seq/√Len: 15.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
417_D421_N7.3411.00
362_Q365_Q6.9751.00
508_E546_N6.8061.00
351_E489_K5.2011.00
65_I82_A5.0601.00
591_E595_T4.3281.00
338_K347_T4.2591.00
587_N591_E4.2521.00
242_A308_I4.0681.00
318_K329_L3.9981.00
350_L353_T3.6971.00
424_T433_A3.5620.99
535_K563_T3.4890.99
341_I488_I3.4840.99
424_T431_P3.4510.99
416_V510_T3.3610.99
371_A375_D3.3490.99
314_S364_D3.3060.99
40_V195_V3.1300.98
43_L209_I3.0680.98
66_R78_I3.0420.98
96_K175_D2.9750.98
29_I130_S2.9450.98
168_I177_L2.8190.97
341_I350_L2.7820.97
329_L332_E2.7690.96
192_H218_S2.7660.96
279_N354_C2.7340.96
140_F176_K2.7310.96
85_V119_L2.7160.96
134_K142_Y2.6570.95
55_R186_Q2.5930.95
238_K378_L2.5260.94
332_E364_D2.4700.93
41_S550_I2.4610.93
349_Q490_E2.4610.93
426_M429_D2.4580.93
478_R497_K2.4520.93
144_T168_I2.4300.93
448_A459_A2.4230.93
395_M449_F2.4040.92
335_D338_K2.3350.91
329_L333_K2.2630.90
142_Y164_I2.2550.89
135_A187_R2.2260.89
330_L333_K2.2010.88
130_S134_K2.1770.88
359_N365_Q2.1770.88
130_S142_Y2.1720.88
522_P525_G2.1380.87
423_E471_Y2.1170.86
214_I393_F2.0870.85
92_L175_D2.0540.84
243_N309_Q2.0370.84
406_G525_G2.0310.84
73_I81_L2.0010.83
508_E512_R2.0000.83
64_K126_K1.9900.82
140_F243_N1.9870.82
242_A305_I1.9860.82
241_L378_L1.9660.82
80_E596_G1.9520.81
29_I134_K1.9400.81
365_Q371_A1.9280.80
25_N142_Y1.9270.80
488_I493_T1.9260.80
303_Q352_N1.9230.80
324_N470_E1.9210.80
417_D423_E1.9120.80
192_H404_Y1.9030.79
346_K492_E1.8990.79
320_R323_F1.8860.79
271_L275_Y1.8770.78
190_V216_Y1.8770.78
241_L374_I1.8710.78
39_F407_N1.8670.78
426_M431_P1.8660.78
38_H56_N1.8650.78
575_S612_R1.8630.78
25_N130_S1.8570.78
192_H219_V1.8540.78
247_I309_Q1.8440.77
401_Y439_D1.8260.76
476_G499_N1.8080.76
480_M486_Y1.8070.76
306_A310_F1.8020.75
309_Q477_K1.8020.75
350_L358_I1.8010.75
170_E632_E1.7970.75
29_I142_Y1.7840.75
206_P256_I1.7790.74
342_T347_T1.7570.74
336_Y360_P1.7540.73
22_E29_I1.7520.73
625_L629_A1.7460.73
414_I438_L1.7430.73
25_N29_I1.7330.72
385_E389_R1.7310.72
244_I381_V1.7170.72
56_N598_D1.7170.72
592_V599_V1.7020.71
25_N134_K1.6970.71
589_K593_L1.6920.71
413_C476_G1.6900.71
107_E111_E1.6830.70
234_Y388_G1.6810.70
41_S207_D1.6440.68
29_I128_T1.6370.68
246_R309_Q1.6260.67
422_M433_A1.6190.67
616_K625_L1.6130.67
318_K332_E1.6130.67
126_K612_R1.6050.66
510_T513_N1.6040.66
84_L178_I1.5880.66
344_N479_A1.5850.65
56_N86_Y1.5820.65
511_C527_I1.5770.65
535_K561_Q1.5710.65
303_Q356_A1.5710.65
245_I257_I1.5700.65
269_L301_I1.5680.65
317_I329_L1.5570.64
382_Q388_G1.5310.63
219_V393_F1.5280.62
516_A525_G1.5030.61
422_M517_E1.5020.61
14_D18_K1.4940.61
336_Y341_I1.4920.61
325_M468_T1.4880.60
309_Q486_Y1.4870.60
159_Q614_K1.4850.60
512_R548_K1.4660.59
320_R395_M1.4590.59
211_E386_K1.4540.58
413_C499_N1.4500.58
229_L247_I1.4400.58
168_I186_Q1.4400.58
10_A333_K1.4330.57
242_A502_Y1.4300.57
511_C549_M1.4300.57
456_D459_A1.4290.57
312_L374_I1.4190.57
243_N477_K1.4190.57
305_I308_I1.4130.56
109_Y174_A1.3990.55
126_K575_S1.3970.55
83_A91_K1.3950.55
271_L593_L1.3850.55
624_L628_V1.3840.55
256_I260_V1.3750.54
441_F462_M1.3680.54
320_R458_L1.3630.53
306_A513_N1.3610.53
502_Y558_K1.3590.53
399_S442_E1.3580.53
27_K616_K1.3490.53
521_N525_G1.3480.53
83_A592_V1.3450.52
237_S460_T1.3410.52
242_A312_L1.3410.52
6_L10_A1.3310.52
199_I221_I1.3270.51
440_V444_F1.3250.51
206_P253_N1.3230.51
205_Q256_I1.3230.51
395_M445_L1.3190.51
577_G601_T1.3120.51
388_G404_Y1.3090.50
60_R572_L1.3090.50
128_T142_Y1.3090.50
125_S156_N1.3090.50
410_I514_I1.3070.50
358_I361_E1.3070.50
15_C338_K1.3000.50
556_F598_D1.2960.50
516_A522_P1.2940.50
72_V118_K1.2920.49
187_R217_H1.2830.49
55_R208_R1.2800.49
209_I502_Y1.2790.49
280_P354_C1.2790.49
271_L373_V1.2780.49
485_R494_H1.2660.48
128_T133_R1.2650.48
43_L156_N1.2650.48
250_R309_Q1.2610.48
43_L195_V1.2570.48
342_T345_G1.2480.47
421_N513_N1.2420.47
297_Q301_I1.2380.46
126_K574_N1.2350.46
170_E624_L1.2350.46
246_R486_Y1.2290.46
520_L525_G1.2290.46
18_K138_A1.2270.46
329_L364_D1.2230.46
319_R457_D1.2190.45
406_G520_L1.2190.45
228_V585_H1.2140.45
312_L366_L1.2120.45
445_L462_M1.2120.45
84_L174_A1.2050.45
521_N524_H1.2010.44
53_V556_F1.2010.44
349_Q489_K1.1980.44
157_K186_Q1.1980.44
131_K134_K1.1950.44
174_A178_I1.1920.44
57_G249_A1.1910.44
395_M448_A1.1890.44
5_Y8_L1.1750.43
239_V312_L1.1750.43
384_S545_A1.1750.43
13_Y161_Y1.1720.43
169_I174_A1.1710.43
207_D260_V1.1690.43
205_Q208_R1.1680.43
131_K142_Y1.1660.42
422_M514_I1.1640.42
318_K326_E1.1630.42
8_L545_A1.1620.42
302_H486_Y1.1610.42
248_C256_I1.1590.42
279_N303_Q1.1540.42
25_N131_K1.1490.42
4_K630_I1.1410.41
128_T134_K1.1390.41
266_R273_E1.1390.41
9_L634_L1.1330.41
509_A513_N1.1290.40
326_E368_E1.1270.40
82_A115_R1.1270.40
506_E544_K1.1270.40
328_R484_E1.1260.40
18_K336_Y1.1260.40
229_L285_K1.1200.40
144_T171_L1.1140.40
232_G240_C1.1130.40
38_H91_K1.1120.40
540_E567_A1.1120.40
38_H598_D1.1100.39
128_T164_I1.1060.39
237_S241_L1.1000.39
65_I119_L1.0990.39
16_E20_V1.0970.39
427_I432_Y1.0960.39
629_A632_E1.0950.39
465_Y469_G1.0940.39
63_E252_D1.0910.38
335_D435_R1.0900.38
308_I487_F1.0880.38
416_V513_N1.0870.38
279_N352_N1.0860.38
336_Y358_I1.0840.38
501_Y529_N1.0830.38
29_I133_R1.0810.38
22_E128_T1.0800.38
166_D519_G1.0790.38
477_K494_H1.0760.38
378_L382_Q1.0720.37
65_I85_V1.0710.37
41_S412_G1.0710.37
249_A254_L1.0670.37
64_K612_R1.0670.37
57_G189_V1.0650.37
556_F599_V1.0640.37
52_H56_N1.0630.37
302_H480_M1.0560.37
537_I561_Q1.0560.37
121_S190_V1.0470.36
361_E365_Q1.0470.36
339_N347_T1.0440.36
400_L509_A1.0430.36
84_L109_Y1.0430.36
140_F175_D1.0420.36
161_Y300_K1.0400.36
40_V43_L1.0400.36
38_H86_Y1.0390.36
247_I486_Y1.0380.36
466_L545_A1.0380.36
51_Q212_E1.0370.36
142_Y191_D1.0370.36
333_K364_D1.0370.36
91_K94_L1.0330.35
548_K593_L1.0310.35
323_F440_V1.0280.35
347_T488_I1.0260.35
13_Y190_V1.0240.35
10_A13_Y1.0240.35
257_I481_T1.0210.35
466_L469_G1.0180.35
590_A597_T1.0150.34
457_D460_T1.0110.34
200_Y256_I1.0090.34
231_I395_M1.0090.34
338_K361_E1.0080.34
362_Q371_A1.0060.34
56_N599_V1.0050.34
205_Q260_V1.0020.34
532_T609_E1.0010.34
516_A521_N1.0010.34
53_V150_K0.9990.34
504_L548_K0.9990.34
51_Q55_R0.9980.34
25_N127_Y0.9970.34
135_A217_H0.9970.34
513_N516_A0.9960.34
134_K164_I0.9960.34
132_L191_D0.9960.34
281_A354_C0.9920.33
238_K374_I0.9890.33
592_V598_D0.9890.33
331_L334_I0.9880.33
590_A594_S0.9820.33
61_V189_V0.9790.33
228_V510_T0.9780.33
422_M513_N0.9760.33
87_Y586_F0.9740.32
247_I477_K0.9710.32
206_P606_V0.9700.32
331_L358_I0.9700.32
279_N301_I0.9680.32
437_L441_F0.9680.32
10_A31_N0.9660.32
337_D375_D0.9660.32
179_T182_A0.9630.32
83_A599_V0.9630.32
246_R482_T0.9620.32
314_S541_D0.9610.32
237_S291_P0.9600.32
244_I599_V0.9580.32
444_F459_A0.9550.31
587_N595_T0.9510.31
200_Y250_R0.9510.31
540_E544_K0.9470.31
284_P299_T0.9460.31
54_L465_Y0.9460.31
228_V442_E0.9420.31
556_F601_T0.9420.31
599_V615_V0.9410.31
96_K105_L0.9400.31
91_K556_F0.9400.31
133_R142_Y0.9380.31
393_F413_C0.9380.31
481_T488_I0.9360.31
279_N356_A0.9360.31
242_A374_I0.9350.31
250_R486_Y0.9340.30
13_Y462_M0.9300.30
127_Y130_S0.9280.30
259_D477_K0.9260.30
13_Y412_G0.9240.30
361_E435_R0.9240.30
310_F331_L0.9210.30
233_A559_A0.9190.30
403_K435_R0.9140.30
243_N247_I0.9130.29
142_Y620_V0.9110.29
53_V596_G0.9110.29
56_N91_K0.9110.29
284_P505_R0.9100.29
340_E347_T0.9080.29
73_I382_Q0.9070.29
29_I131_K0.9010.29
393_F537_I0.8980.29
55_R309_Q0.8940.29
56_N556_F0.8910.28
264_N300_K0.8860.28
28_A627_E0.8850.28
412_G471_Y0.8840.28
41_S476_G0.8830.28
53_V56_N0.8820.28
362_Q491_K0.8820.28
231_I391_M0.8790.28
435_R622_E0.8790.28
407_N528_I0.8770.28
417_D424_T0.8760.28
336_Y350_L0.8750.28
63_E266_R0.8730.28
209_I213_L0.8720.28
29_I164_I0.8710.28
156_N622_E0.8680.27
29_I127_Y0.8670.27
462_M465_Y0.8650.27
166_D189_V0.8650.27
541_D550_I0.8630.27
322_N359_N0.8620.27
20_V31_N0.8620.27
163_E410_I0.8600.27
52_H598_D0.8580.27
309_Q494_H0.8580.27
127_Y131_K0.8560.27
4_K626_Q0.8540.27
257_I347_T0.8520.27
84_L108_W0.8510.27
440_V545_A0.8490.27
438_L545_A0.8490.27
292_E528_I0.8480.27
427_I440_V0.8460.26
13_Y493_T0.8460.26
218_S404_Y0.8450.26
86_Y570_T0.8440.26
528_I617_E0.8440.26
22_E142_Y0.8430.26
38_H83_A0.8430.26
419_N423_E0.8430.26
30_L625_L0.8430.26
294_E343_L0.8420.26
247_I550_I0.8420.26
215_N558_K0.8410.26
254_L498_K0.8410.26
485_R493_T0.8390.26
393_F476_G0.8360.26
423_E499_N0.8360.26
144_T181_L0.8360.26
56_N601_T0.8340.26
210_M391_M0.8330.26
388_G392_N0.8330.26
8_L466_L0.8330.26
587_N597_T0.8290.26
400_L438_L0.8260.26
578_M607_D0.8250.26
28_A132_L0.8250.26
187_R216_Y0.8250.26
210_M514_I0.8240.26
38_H599_V0.8240.26
570_T619_N0.8220.25
410_I549_M0.8210.25
278_D299_T0.8210.25
393_F412_G0.8210.25
298_I545_A0.8170.25
350_L488_I0.8170.25
284_P545_A0.8160.25
200_Y394_M0.8120.25
47_Y307_M0.8100.25
70_S78_I0.8100.25
229_L528_I0.8100.25
269_L297_Q0.8080.25
450_A595_T0.8070.25
327_E470_E0.8050.25
307_M625_L0.8020.25
56_N218_S0.7990.24
361_E433_A0.7980.24
186_Q486_Y0.7980.24
90_D192_H0.7950.24
591_E597_T0.7930.24
480_M494_H0.7930.24
171_L206_P0.7910.24
545_A548_K0.7910.24
264_N380_S0.7900.24
545_A602_V0.7890.24
28_A511_C0.7880.24
550_I578_M0.7860.24
109_Y601_T0.7840.24
10_A210_M0.7840.24
183_Y237_S0.7830.24
280_P448_A0.7830.24
38_H53_V0.7830.24
25_N129_R0.7830.24
349_Q353_T0.7810.24
190_V314_S0.7800.24
25_N164_I0.7800.24
58_S615_V0.7770.24
246_R250_R0.7750.23
83_A356_A0.7740.23
55_R117_I0.7740.23
620_V623_E0.7720.23
145_E320_R0.7720.23
132_L585_H0.7710.23
271_L355_F0.7700.23
8_L438_L0.7690.23
119_L392_N0.7690.23
83_A601_T0.7680.23
127_Y134_K0.7670.23
169_I286_A0.7660.23
117_I200_Y0.7660.23
82_A219_V0.7640.23
104_A503_Y0.7640.23
49_A209_I0.7640.23
214_I219_V0.7630.23
144_T221_I0.7620.23
240_C487_F0.7620.23
38_H570_T0.7620.23
275_Y367_L0.7600.23
177_L528_I0.7580.23
15_C245_I0.7580.23
605_L627_E0.7570.23
98_D594_S0.7570.23
507_D511_C0.7570.23
28_A143_I0.7560.23
412_G441_F0.7550.23
418_E503_Y0.7550.23
196_V520_L0.7490.22
205_Q532_T0.7490.22
392_N450_A0.7480.22
392_N449_F0.7470.22
56_N545_A0.7460.22
508_E635_R0.7450.22
382_Q457_D0.7430.22
263_I570_T0.7420.22
3_S362_Q0.7410.22
139_Q350_L0.7410.22
303_Q357_T0.7390.22
196_V219_V0.7390.22
27_K632_E0.7380.22
407_N526_H0.7380.22
131_K191_D0.7380.22
454_E495_K0.7360.22
148_L545_A0.7350.22
316_I319_R0.7340.22
308_I374_I0.7310.22
134_K620_V0.7300.22
410_I513_N0.7300.22
137_P540_E0.7290.22
263_I615_V0.7280.22
448_A548_K0.7270.22
204_P259_D0.7270.22
108_W217_H0.7260.22
297_Q532_T0.7250.22
200_Y248_C0.7250.22
409_L575_S0.7240.21
67_D576_Y0.7220.21
31_N386_K0.7210.21
184_S244_I0.7200.21
133_R164_I0.7200.21
171_L352_N0.7190.21
317_I624_L0.7180.21
598_D601_T0.7180.21
10_A457_D0.7170.21
307_M436_E0.7140.21
624_L632_E0.7140.21
413_C500_P0.7130.21
5_Y414_I0.7130.21
459_A545_A0.7130.21
247_I494_H0.7110.21
22_E164_I0.7100.21
299_T384_S0.7100.21
393_F582_A0.7080.21
244_I373_V0.7060.21
264_N302_H0.7060.21
296_K300_K0.7050.21
250_R477_K0.7030.21
199_I318_K0.7020.21
476_G529_N0.7020.21
358_I623_E0.7010.21
343_L350_L0.7000.21
512_R523_D0.6990.21
248_C437_L0.6990.21
56_N83_A0.6990.21
165_I184_S0.6980.21
281_A303_Q0.6980.21
29_I129_R0.6970.20
182_A582_A0.6970.20
264_N270_N0.6970.20
574_N620_V0.6970.20
499_N576_Y0.6970.20
516_A520_L0.6950.20
186_Q477_K0.6930.20
86_Y407_N0.6930.20
410_I551_V0.6920.20
47_Y317_I0.6920.20
56_N615_V0.6910.20
503_Y562_S0.6910.20
169_I414_I0.6880.20
450_A456_D0.6880.20
528_I571_L0.6880.20
130_S164_I0.6860.20
186_Q259_D0.6860.20
53_V216_Y0.6850.20
69_F73_I0.6820.20
432_Y440_V0.6820.20
136_L145_E0.6820.20
254_L601_T0.6810.20
29_I620_V0.6790.20
53_V376_K0.6790.20
204_P498_K0.6780.20
505_R551_V0.6770.20
68_I118_K0.6770.20
368_E371_A0.6770.20
167_Q171_L0.6760.20
299_T303_Q0.6750.20
61_V256_I0.6740.20
422_M510_T0.6730.20
78_I150_K0.6730.20
29_I569_Y0.6720.20
412_G476_G0.6720.20
169_I415_P0.6710.20
303_Q339_N0.6710.20
358_I499_N0.6710.20
80_E156_N0.6710.20
135_A620_V0.6700.20
232_G355_F0.6700.20
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495_K611_E0.6530.19
441_F473_S0.6520.19
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279_N487_F0.6510.19
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572_L620_V0.6500.19
318_K435_R0.6500.19
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320_R460_T0.6460.19
300_K596_G0.6460.19
92_L336_Y0.6450.19
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324_N426_M0.6450.19
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253_N407_N0.6430.19
130_S191_D0.6420.19
171_L574_N0.6420.19
200_Y210_M0.6410.19
38_H601_T0.6400.18
271_L585_H0.6390.18
52_H86_Y0.6390.18
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150_K266_R0.6370.18
498_K588_S0.6370.18
39_F409_L0.6370.18
64_K575_S0.6360.18
6_L271_L0.6350.18
61_V278_D0.6340.18
38_H556_F0.6340.18
58_S128_T0.6340.18
433_A500_P0.6330.18
78_I145_E0.6320.18
280_P386_K0.6320.18
95_I104_A0.6320.18
186_Q309_Q0.6310.18
15_C332_E0.6300.18
18_K491_K0.6300.18
106_N433_A0.6300.18
165_I397_K0.6300.18
129_R134_K0.6280.18
43_L628_V0.6270.18
284_P438_L0.6270.18
620_V624_L0.6260.18
298_I438_L0.6250.18
118_K308_I0.6250.18
375_D500_P0.6230.18
12_K412_G0.6220.18
25_N128_T0.6190.18
362_Q546_N0.6190.18
91_K601_T0.6190.18
324_N424_T0.6180.18
308_I528_I0.6180.18
48_Q177_L0.6180.18
27_K245_I0.6180.18
508_E588_S0.6170.18
4_K15_C0.6160.18
85_V512_R0.6160.18
473_S619_N0.6160.18
298_I511_C0.6160.18
140_F615_V0.6150.18
573_Y613_K0.6130.18
18_K68_I0.6130.18
324_N504_L0.6130.18
334_I350_L0.6120.18
352_N464_W0.6120.18
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558_K561_Q0.6090.17
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419_N544_K0.6090.17
470_E494_H0.6090.17
104_A324_N0.6080.17
50_F116_M0.6080.17
407_N570_T0.6080.17
323_F604_R0.6070.17
209_I294_E0.6070.17
28_A149_Y0.6060.17
60_R244_I0.6060.17
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343_L493_T0.6050.17
445_L465_Y0.6050.17
13_Y51_Q0.6050.17
505_R579_Q0.6050.17
303_Q354_C0.6050.17
475_F491_K0.6040.17
229_L240_C0.6030.17
195_V442_E0.6030.17
149_Y154_A0.6030.17
125_S550_I0.6010.17
280_P345_G0.6010.17
113_I521_N0.6010.17
39_F86_Y0.6000.17
40_V53_V0.6000.17
134_K191_D0.5990.17
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525_G587_N0.5940.17
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274_K293_D0.5890.17
234_Y460_T0.5890.17
336_Y368_E0.5890.17
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264_N491_K0.5840.17
103_E345_G0.5820.17
172_G417_D0.5810.17
41_S597_T0.5810.17
53_V577_G0.5790.17
199_I561_Q0.5780.16
187_R403_K0.5780.16
375_D429_D0.5780.16
178_I253_N0.5770.16
192_H349_Q0.5770.16
124_S209_I0.5770.16
60_R149_Y0.5770.16
380_S487_F0.5770.16
271_L308_I0.5760.16
71_G107_E0.5750.16
173_Q257_I0.5740.16
89_E179_T0.5740.16
17_E139_Q0.5740.16
22_E134_K0.5740.16
111_E115_R0.5740.16
169_I394_M0.5740.16
345_G369_E0.5740.16
574_N612_R0.5730.16
38_H87_Y0.5730.16
289_N391_M0.5730.16
23_I632_E0.5730.16
572_L581_V0.5730.16
624_L627_E0.5720.16
466_L602_V0.5710.16
122_Y196_V0.5710.16
408_L520_L0.5710.16
103_E195_V0.5700.16
13_Y114_H0.5690.16
525_G608_K0.5690.16
284_P465_Y0.5690.16
278_D305_I0.5680.16
76_R98_D0.5680.16
570_T573_Y0.5680.16
169_I617_E0.5670.16
104_A182_A0.5660.16
257_I285_K0.5660.16
435_R517_E0.5660.16
487_F543_I0.5650.16
307_M382_Q0.5650.16
74_Y107_E0.5640.16
134_K586_F0.5640.16
208_R532_T0.5640.16
120_V573_Y0.5640.16
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163_E445_L0.5630.16
241_L389_R0.5630.16
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438_L551_V0.5620.16
249_A581_V0.5610.16
157_K336_Y0.5610.16
214_I622_E0.5610.16
347_T374_I0.5610.16
326_E340_E0.5600.16
117_I558_K0.5590.16
387_L466_L0.5590.16
271_L367_L0.5580.16
388_G460_T0.5580.16
64_K574_N0.5580.16
577_G598_D0.5560.16
10_A16_E0.5560.16
85_V314_S0.5560.16
526_H570_T0.5550.16
253_N387_L0.5550.16
439_D516_A0.5540.16
162_S623_E0.5530.16
113_I264_N0.5530.16
135_A248_C0.5530.16
4_K228_V0.5530.16
57_G192_H0.5520.16
511_C545_A0.5510.16
260_V425_M0.5510.16
17_E632_E0.5500.16
475_F494_H0.5500.16
7_D549_M0.5500.16
257_I581_V0.5490.16
66_R272_A0.5490.16
141_A624_L0.5490.16
143_I164_I0.5490.16
112_T308_I0.5490.16
75_D337_D0.5470.16
62_K140_F0.5470.16
558_K612_R0.5470.16
83_A109_Y0.5470.16
249_A309_Q0.5460.16
258_E266_R0.5460.16
477_K486_Y0.5460.16
57_G149_Y0.5440.15
200_Y207_D0.5440.15
241_L441_F0.5430.15
253_N570_T0.5430.15
73_I403_K0.5420.15
526_H548_K0.5420.15
535_K562_S0.5420.15
294_E536_E0.5410.15
609_E613_K0.5410.15
38_H254_L0.5410.15
21_T624_L0.5410.15
593_L598_D0.5410.15
68_I469_G0.5400.15
238_K371_A0.5400.15
323_F463_A0.5400.15
488_I538_E0.5390.15
41_S413_C0.5380.15
594_S597_T0.5370.15
330_L364_D0.5360.15
117_I360_P0.5360.15
86_Y619_N0.5350.15
125_S184_S0.5350.15
121_S174_A0.5340.15
265_L489_K0.5340.15
375_D454_E0.5340.15
219_V476_G0.5340.15
488_I494_H0.5340.15
373_V419_N0.5330.15
427_I430_K0.5330.15
195_V512_R0.5330.15
151_T582_A0.5320.15
528_I591_E0.5320.15
228_V420_G0.5320.15
38_H216_Y0.5310.15
314_S329_L0.5310.15
248_C314_S0.5310.15
475_F543_I0.5300.15
306_A354_C0.5300.15
171_L572_L0.5290.15
212_E298_I0.5280.15
65_I596_G0.5280.15
235_S395_M0.5280.15
315_P403_K0.5280.15
228_V418_E0.5270.15
440_V443_R0.5260.15
206_P255_D0.5260.15
210_M566_I0.5260.15
25_N133_R0.5250.15
239_V540_E0.5250.15
284_P466_L0.5250.15
104_A152_E0.5250.15
281_A352_N0.5230.15
61_V374_I0.5230.15
352_N356_A0.5230.15
27_K119_L0.5230.15
89_E183_Y0.5230.15
520_L574_N0.5220.15
206_P578_M0.5220.15
41_S478_R0.5220.15
219_V448_A0.5220.15
21_T586_F0.5210.15
192_H402_L0.5210.15
175_D549_M0.5210.15
65_I441_F0.5200.15
157_K204_P0.5190.15
410_I628_V0.5190.15
315_P365_Q0.5190.15
350_L633_S0.5180.15
189_V323_F0.5180.15
231_I234_Y0.5170.15
196_V525_G0.5160.15
392_N489_K0.5150.15
400_L474_L0.5140.15
335_D340_E0.5140.15
41_S266_R0.5140.15
136_L257_I0.5130.15
427_I491_K0.5120.15
610_L624_L0.5120.15
341_I429_D0.5120.15
61_V86_Y0.5120.15
27_K151_T0.5110.15
543_I578_M0.5110.15
113_I180_G0.5110.15
525_G623_E0.5110.15
488_I517_E0.5100.14
317_I580_L0.5100.14
35_G190_V0.5100.14
10_A396_K0.5090.14
610_L613_K0.5090.14
592_V615_V0.5080.14
309_Q505_R0.5080.14
252_D265_L0.5080.14
37_E194_H0.5080.14
274_K380_S0.5080.14
175_D343_L0.5070.14
78_I205_Q0.5070.14
444_F462_M0.5060.14
135_A577_G0.5060.14
264_N267_P0.5050.14
13_Y479_A0.5050.14
377_L466_L0.5050.14
98_D622_E0.5050.14
254_L584_K0.5050.14
284_P602_V0.5040.14
200_Y305_I0.5040.14
31_N135_A0.5040.14
149_Y545_A0.5040.14
22_E25_N0.5040.14
200_Y278_D0.5040.14
302_H305_I0.5040.14
564_T567_A0.5030.14
259_D606_V0.5030.14
403_K627_E0.5020.14
55_R441_F0.5020.14
130_S620_V0.5010.14
623_E627_E0.5010.14
214_I345_G0.5010.14
512_R525_G0.5010.14
520_L627_E0.5010.14
181_L600_L0.5000.14
264_N606_V0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2z72A 1 0.4852 98.4 0.969 Contact Map
2dfjA 2 0.3744 97.9 0.973 Contact Map
1fjmA 1 0.4415 97.7 0.975 Contact Map
4il1A 1 0.6256 97.6 0.975 Contact Map
4movA 1 0.4321 97.5 0.976 Contact Map
1auiA 1 0.4758 97.5 0.976 Contact Map
3h63A 1 0.4696 97.2 0.977 Contact Map
3icfA 2 0.4602 97.2 0.977 Contact Map
4ja7A 1 0.6115 97 0.978 Contact Map
3qfmA 2 0.3885 96.8 0.978 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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