GREMLIN Database
YBBK - Uncharacterized protein YbbK
UniProt: Q45584 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 151 (140)
Sequences: 1722 (1297)
Seq/√Len: 109.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
12_E19_H3.4521.00
127_S135_K3.1071.00
103_K144_E2.7641.00
52_A77_V2.4801.00
102_L131_A2.4761.00
14_R20_A2.4131.00
50_E73_S2.3221.00
132_A136_Q2.3051.00
41_L47_T2.2841.00
104_E143_S2.2661.00
50_E72_A2.2631.00
116_N120_S1.9891.00
112_G127_S1.9881.00
83_E87_K1.9631.00
92_A97_A1.9451.00
71_T75_E1.9391.00
102_L134_L1.9191.00
133_L137_A1.9041.00
89_L133_L1.8081.00
29_V34_A1.8081.00
64_N136_Q1.7041.00
28_L32_K1.7011.00
105_N123_K1.6851.00
87_K90_A1.6651.00
28_L31_E1.6331.00
9_G34_A1.6131.00
3_L100_V1.6111.00
68_K76_D1.6041.00
79_E83_E1.6031.00
113_F125_T1.5961.00
9_G36_M1.5741.00
3_L134_L1.5741.00
63_L82_M1.5741.00
3_L92_A1.5081.00
29_V32_K1.4891.00
111_S135_K1.4651.00
133_L136_Q1.4611.00
127_S132_A1.4241.00
6_S11_I1.4191.00
11_I36_M1.4171.00
37_A42_L1.4111.00
100_V139_Y1.3881.00
93_K137_A1.3661.00
43_G84_G1.3631.00
21_A26_R1.3391.00
99_A142_I1.3361.00
27_K31_E1.3210.99
50_E71_T1.3130.99
55_I70_V1.3040.99
114_I126_G1.2940.99
23_E27_K1.2870.99
54_I69_I1.2630.99
100_V130_T1.2590.99
3_L97_A1.2520.99
45_F80_L1.2350.99
89_L137_A1.2290.99
22_S25_I1.2000.99
88_T134_L1.1950.99
27_K30_D1.1860.99
85_A133_L1.1770.99
4_V25_I1.1410.98
81_Y108_S1.1210.98
86_A133_L1.1190.98
99_A140_R1.1070.98
9_G29_V1.0850.98
116_N119_F1.0830.98
57_G67_A1.0780.98
115_Y119_F1.0730.98
63_L66_T1.0490.97
87_K91_Y1.0440.97
14_R19_H1.0400.97
41_L44_G1.0380.97
56_G67_A1.0170.97
90_A93_K1.0170.97
81_Y84_G1.0120.97
65_G69_I0.9820.96
14_R18_S0.9730.96
117_G121_G0.9700.96
63_L67_A0.9690.96
90_A137_A0.9570.96
54_I129_V0.9550.95
111_S143_S0.9500.95
4_V34_A0.9480.95
105_N145_N0.9440.95
112_G146_E0.9380.95
111_S141_V0.9320.95
82_M132_A0.9090.94
75_E80_L0.8880.93
26_R29_V0.8800.93
89_L138_G0.8690.93
53_E117_G0.8590.92
53_E119_F0.8460.92
66_T69_I0.8430.91
116_N121_G0.8190.90
57_G63_L0.8160.90
90_A94_E0.8140.90
104_E111_S0.8100.90
28_L34_A0.8060.90
92_A139_Y0.7960.89
13_C41_L0.7950.89
37_A84_G0.7950.89
71_T77_V0.7850.88
56_G63_L0.7840.88
43_G108_S0.7840.88
41_L94_E0.7820.88
105_N113_F0.7800.88
42_L91_Y0.7800.88
16_N20_A0.7740.88
41_L87_K0.7720.87
20_A144_E0.7690.87
57_G65_G0.7670.87
91_Y95_I0.7630.87
16_N103_K0.7580.86
52_A69_I0.7570.86
108_S130_T0.7560.86
23_E26_R0.7460.86
85_A129_V0.7360.85
104_E112_G0.7360.85
54_I132_A0.7350.85
88_T130_T0.7340.85
2_I99_A0.7300.84
12_E21_A0.7290.84
118_T122_K0.7270.84
113_F145_N0.7240.84
115_Y121_G0.7200.83
2_I32_K0.7180.83
91_Y94_E0.7170.83
42_L88_T0.7160.83
2_I101_I0.7150.83
22_S103_K0.7120.83
45_F77_V0.7120.83
78_T82_M0.7060.82
83_E86_A0.7040.82
97_A101_I0.7000.82
111_S127_S0.6970.81
104_E144_E0.6960.81
2_I34_A0.6880.81
6_S10_G0.6790.80
28_L33_K0.6780.80
9_G13_C0.6720.79
43_G80_L0.6670.79
24_K47_T0.6610.78
104_E145_N0.6530.77
92_A100_V0.6500.77
8_L108_S0.6420.76
45_F81_Y0.6360.75
25_I28_L0.6350.75
10_G19_H0.6340.75
43_G52_A0.6320.75
129_V133_L0.6280.74
82_M86_A0.6230.74
69_I77_V0.6210.73
97_A139_Y0.6180.73
102_L109_C0.6180.73
67_A129_V0.6150.73
85_A88_T0.6130.73
51_P72_A0.6110.72
56_G65_G0.6090.72
131_A141_V0.6040.71
3_L130_T0.6020.71
114_I124_I0.6010.71
97_A100_V0.5950.70
68_K81_Y0.5940.70
102_L143_S0.5930.70
43_G77_V0.5910.70
23_E64_N0.5850.69
142_I146_E0.5840.69
3_L37_A0.5780.68
116_N122_K0.5770.68
2_I142_I0.5760.68
41_L90_A0.5700.67
57_G66_T0.5690.67
35_V96_N0.5630.66
8_L45_F0.5630.66
13_C47_T0.5590.66
13_C142_I0.5590.66
6_S13_C0.5570.65
77_V80_L0.5550.65
20_A47_T0.5500.64
9_G32_K0.5490.64
112_G143_S0.5480.64
39_P88_T0.5470.64
53_E121_G0.5470.64
46_S140_R0.5420.63
52_A81_Y0.5390.63
86_A137_A0.5390.63
2_I33_K0.5380.63
131_A135_K0.5380.63
24_K99_A0.5360.62
86_A90_A0.5360.62
33_K46_S0.5360.62
117_G126_G0.5350.62
11_I41_L0.5350.62
50_E70_V0.5350.62
127_S131_A0.5290.61
2_I28_L0.5290.61
24_K90_A0.5280.61
20_A105_N0.5280.61
4_V36_M0.5240.61
45_F52_A0.5160.59
135_K143_S0.5150.59
85_A130_T0.5150.59
101_I142_I0.5130.59
65_G68_K0.5110.59
4_V22_S0.5110.59
143_S146_E0.5110.59
53_E116_N0.5100.59
51_P120_S0.5070.58
46_S50_E0.5010.57
84_G104_E0.5000.57
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3l8hA 1 0.649 10.2 0.951 Contact Map
4k8kA 2 0.9139 8.4 0.953 Contact Map
2hxvA 2 0.7947 8 0.954 Contact Map
2b3zA 3 0.7417 6.8 0.955 Contact Map
2gmgA 1 0.6556 6.3 0.956 Contact Map
4f02C 1 0.1325 6.2 0.956 Contact Map
3h49A 2 0.9007 4.5 0.959 Contact Map
1n62A 1 0.8013 4.4 0.959 Contact Map
1su3A 4 0.5166 4.4 0.959 Contact Map
1vc4A 2 0.6424 4.4 0.959 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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