YBEC - BACSU - GREMLIN Contacts

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YBEC - Probable amino acid-proton symporter YbeC

UniProt:	Q45577	Sequences: MNQLHRRMGTFSLMMVGLGSMIGSGWLFGAWRAAQIAGPAAIISWVIGMVVILFIALSYSELGSMFPEAGGMVKYTQYSHGSFIGFIAGWANWIAIVSVIPVEAVASVQYMSSWPWEWAKWTSGLVKNGTLTGEGLAFASVLLLIYFLLNYWTVNLFSKANSLITIFKIIIPGLTIGALLFVGFHGENFTGGQSIAPNGWASVLTAVATSGIVFAFNGFQSPINMAGEAKNPGKSIPIAVVGSLFVATVIYVLLQIAFIGAVNPSDIAHGWSHLNFNSPFADLAIALNINWLVIVLYADAFVSPSGTGITYTATTSRMIYGMEKNKYMPSIFGKLHPIYGVPRQAMFFNLIVSFIFLFLFRGWGVLAEIISVATLISYITGPITVMTLRRTGKDLYRPLRLKGLNVIAPLGFIFASLVLYWARWPLTGQVLFIILIGLPIYFYYQAKAKWKGFGRNFKAGVWMVFYLLAMMVISYLGSDKFGGLNVIHYGWDMVLIAMVSLVFYVWALKSGYQTEYLKDAKEINSQLLNGQSEAAAGKE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	539 (422)
Sequences:	22601 (14285)
Seq/√Len:	695.4

ECOLI - ANSP PUUP POTE PLAP LYSP PROY AROP YIFK FRLA MMUP GADC GABP PHEP ADIC CYCA YJEM ARCD YBAT YGJI YJEH CADB YCAM
BACSU - YBEC ASPP YHDG ROCC YBXG GABP YFNA STET YTNA HUTM YBGF YDAO YDGF YVBW AAPA ROCE ARCD YECA YCGH GERBB YNDE GERAB
HALSA - Q9HQB3 Q9HSL5 Q9HHU7
SULSO - Q97X49 Q97WS3 Q97Z63 Q97XM0 Q97U05 Q97VA6 Q97VA8 Q97ZB5 Q7LXI7 Q97U33 Q97WD4 Q97Y76 Q97VR4 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
331_I	344_Q	4.364	1.00
147_F	350_L	4.114	1.00
387_T	391_T	3.489	1.00
379_I	412_F	3.157	1.00
49_M	248_T	3.125	1.00
334_K	344_Q	3.096	1.00
234_K	238_I	2.993	1.00
9_G	230_K	2.834	1.00
231_N	234_K	2.793	1.00
336_H	339_Y	2.788	1.00
229_A	235_S	2.665	1.00
73_V	325_N	2.657	1.00
323_E	333_G	2.629	1.00
331_I	334_K	2.586	1.00
179_L	257_A	2.582	1.00
140_S	354_F	2.485	1.00
336_H	343_R	2.482	1.00
89_G	322_M	2.481	1.00
14_M	242_G	2.403	1.00
10_T	242_G	2.386	1.00
291_W	295_V	2.352	1.00
177_G	181_F	2.271	1.00
382_P	411_G	2.222	1.00
227_G	324_K	2.220	1.00
77_Q	85_G	2.208	1.00
61_E	389_R	2.203	1.00
433_I	437_G	2.158	1.00
320_Y	324_K	2.123	1.00
144_L	354_F	2.095	1.00
147_F	346_M	2.095	1.00
148_L	152_W	2.084	1.00
151_Y	343_R	2.081	1.00
10_T	235_S	2.044	1.00
140_S	357_L	2.043	1.00
155_N	159_K	2.039	1.00
347_F	351_I	2.038	1.00
13_L	229_A	2.034	1.00
409_P	413_I	2.022	1.00
282_D	285_I	2.020	1.00
77_Q	82_S	1.980	1.00
263_N	266_D	1.967	1.00
228_E	317_R	1.956	1.00
166_I	170_I	1.953	1.00
238_I	242_G	1.937	1.00
332_F	348_F	1.925	1.00
139_A	357_L	1.888	1.00
80_H	387_T	1.887	1.00
50_V	54_F	1.871	1.00
9_G	12_S	1.863	1.00
58_S	382_P	1.863	1.00
10_T	14_M	1.861	1.00
439_P	443_Y	1.860	1.00
93_W	349_N	1.828	1.00
326_K	330_S	1.822	1.00
144_L	350_L	1.816	1.00
14_M	246_V	1.811	1.00
266_D	286_A	1.798	1.00
406_V	410_L	1.784	1.00
33_A	41_A	1.755	1.00
431_L	435_L	1.744	1.00
80_H	383_I	1.731	1.00
282_D	286_A	1.728	1.00
76_T	88_A	1.712	1.00
88_A	380_T	1.712	1.00
170_I	174_L	1.702	1.00
437_G	440_I	1.699	1.00
446_A	449_K	1.690	1.00
12_S	162_S	1.684	1.00
51_V	414_F	1.678	1.00
387_T	390_R	1.672	1.00
100_I	353_S	1.664	1.00
17_G	243_S	1.652	1.00
231_N	235_S	1.637	1.00
4_L	335_L	1.635	1.00
8_M	12_S	1.622	1.00
54_F	410_L	1.615	1.00
241_V	245_F	1.600	1.00
151_Y	347_F	1.597	1.00
104_A	308_G	1.596	1.00
276_F	282_D	1.594	1.00
5_H	340_G	1.578	1.00
383_I	412_F	1.566	1.00
50_V	410_L	1.561	1.00
143_L	353_S	1.551	1.00
140_S	144_L	1.550	1.00
403_G	407_I	1.546	1.00
339_Y	343_R	1.537	1.00
413_I	417_L	1.533	1.00
111_M	138_F	1.529	1.00
134_E	137_A	1.522	1.00
90_W	437_G	1.521	1.00
344_Q	348_F	1.519	1.00
315_T	349_N	1.500	1.00
245_F	249_V	1.496	1.00
150_N	309_I	1.493	1.00
330_S	333_G	1.491	1.00
133_G	137_A	1.473	1.00
205_T	209_T	1.465	1.00
81_G	84_I	1.447	1.00
147_F	347_F	1.440	1.00
200_W	203_V	1.437	1.00
285_I	293_V	1.423	1.00
404_L	408_A	1.415	1.00
152_W	339_Y	1.415	1.00
443_Y	447_K	1.404	1.00
442_F	446_A	1.401	1.00
107_S	142_L	1.401	1.00
48_G	212_I	1.393	1.00
143_L	350_L	1.382	1.00
330_S	334_K	1.380	1.00
56_A	244_L	1.378	1.00
40_A	203_V	1.376	1.00
444_Y	448_A	1.370	1.00
56_A	240_V	1.367	1.00
176_I	253_L	1.365	1.00
104_A	143_L	1.364	1.00
66_F	78_Y	1.360	1.00
235_S	238_I	1.359	1.00
334_K	343_R	1.358	1.00
58_S	408_A	1.355	1.00
79_S	384_T	1.351	1.00
80_H	84_I	1.350	1.00
169_I	173_G	1.349	1.00
294_I	298_A	1.340	1.00
42_I	256_I	1.335	1.00
202_S	206_A	1.335	1.00
316_S	346_M	1.322	1.00
171_I	299_D	1.318	1.00
12_S	158_S	1.316	1.00
438_L	442_F	1.315	1.00
319_I	345_A	1.315	1.00
383_I	387_T	1.308	1.00
146_Y	308_G	1.306	1.00
249_V	253_L	1.303	1.00
427_T	430_V	1.300	1.00
440_I	443_Y	1.298	1.00
231_N	238_I	1.291	1.00
278_S	282_D	1.287	1.00
225_M	313_A	1.286	1.00
180_L	257_A	1.283	1.00
69_A	227_G	1.278	1.00
199_G	202_S	1.277	1.00
320_Y	335_L	1.270	1.00
390_R	393_K	1.262	1.00
426_L	430_V	1.258	1.00
276_F	279_P	1.257	1.00
440_I	444_Y	1.252	1.00
107_S	301_F	1.250	1.00
432_F	436_I	1.249	1.00
83_F	444_Y	1.239	1.00
136_L	140_S	1.236	1.00
40_A	196_A	1.227	1.00
21_M	247_A	1.225	1.00
285_I	290_N	1.220	1.00
10_T	238_I	1.210	1.00
435_L	439_P	1.208	1.00
405_N	409_P	1.202	1.00
8_M	158_S	1.202	1.00
76_T	380_T	1.197	1.00
55_I	382_P	1.193	1.00
202_S	205_T	1.191	1.00
57_L	241_V	1.190	1.00
344_Q	347_F	1.187	1.00
44_S	206_A	1.183	1.00
386_M	409_P	1.176	1.00
319_I	328_M	1.173	1.00
336_H	341_V	1.169	1.00
16_V	225_M	1.168	1.00
393_K	397_R	1.165	1.00
324_K	333_G	1.162	1.00
28_F	106_A	1.159	1.00
428_G	432_F	1.159	1.00
426_L	429_Q	1.155	1.00
392_G	395_L	1.146	1.00
7_R	230_K	1.143	1.00
181_F	185_H	1.142	1.00
230_K	235_S	1.138	1.00
103_E	307_T	1.126	1.00
160_A	164_I	1.124	1.00
232_P	237_P	1.124	1.00
13_L	239_A	1.122	1.00
385_V	408_A	1.119	1.00
430_V	434_I	1.116	1.00
74_K	78_Y	1.111	1.00
379_I	416_S	1.109	1.00
406_V	409_P	1.108	1.00
76_T	84_I	1.099	1.00
205_T	208_A	1.098	1.00
411_G	415_A	1.097	1.00
201_A	205_T	1.097	1.00
203_V	208_A	1.093	1.00
149_L	160_A	1.092	1.00
175_T	179_L	1.086	1.00
46_V	252_V	1.085	1.00
65_M	395_L	1.081	1.00
444_Y	447_K	1.077	1.00
426_L	433_I	1.077	1.00
8_M	13_L	1.076	1.00
334_K	337_P	1.076	1.00
179_L	261_A	1.075	1.00
417_L	421_W	1.075	1.00
11_F	15_M	1.070	1.00
445_Q	449_K	1.067	1.00
63_G	75_Y	1.059	1.00
78_Y	392_G	1.058	1.00
93_W	319_I	1.058	1.00
59_Y	72_M	1.054	1.00
203_V	207_V	1.053	1.00
68_E	74_K	1.051	1.00
173_G	177_G	1.042	1.00
86_F	90_W	1.041	1.00
263_N	286_A	1.041	1.00
390_R	405_N	1.037	1.00
204_L	207_V	1.034	1.00
17_G	222_P	1.034	1.00
443_Y	446_A	1.028	1.00
187_E	190_T	1.028	1.00
174_L	178_A	1.027	1.00
65_M	397_R	1.025	1.00
18_L	246_V	1.023	1.00
200_W	204_L	1.023	1.00
186_G	190_T	1.013	1.00
351_I	355_I	1.011	1.00
437_G	441_Y	1.006	1.00
412_F	416_S	1.001	1.00
161_N	309_I	1.001	1.00
379_I	415_A	1.001	1.00
399_L	402_K	1.000	1.00
108_V	138_F	0.999	1.00
111_M	115_P	0.994	1.00
427_T	431_L	0.994	1.00
193_Q	196_A	0.982	1.00
11_F	162_S	0.980	1.00
141_V	145_I	0.979	1.00
403_G	408_A	0.977	1.00
335_L	340_G	0.977	1.00
403_G	406_V	0.976	1.00
137_A	141_V	0.975	1.00
408_A	412_F	0.973	1.00
428_G	431_L	0.970	1.00
164_I	306_G	0.969	1.00
429_Q	432_F	0.968	1.00
15_M	162_S	0.967	1.00
432_F	435_L	0.965	1.00
382_P	412_F	0.965	1.00
279_P	283_L	0.964	1.00
154_V	313_A	0.962	1.00
7_R	155_N	0.962	1.00
144_L	148_L	0.959	1.00
416_S	420_Y	0.959	1.00
73_V	321_G	0.958	1.00
184_F	260_G	0.953	1.00
217_N	374_T	0.946	1.00
415_A	418_V	0.940	1.00
394_D	397_R	0.940	1.00
22_I	25_G	0.939	1.00
312_T	350_L	0.938	1.00
392_G	397_R	0.934	1.00
159_K	162_S	0.934	1.00
147_F	151_Y	0.932	1.00
49_M	216_F	0.932	1.00
159_K	163_L	0.928	1.00
242_G	246_V	0.928	1.00
68_E	78_Y	0.925	1.00
176_I	180_L	0.923	1.00
204_L	208_A	0.922	1.00
151_Y	341_V	0.919	1.00
379_I	383_I	0.917	1.00
426_L	437_G	0.915	1.00
12_S	159_K	0.914	1.00
372_V	430_V	0.909	1.00
83_F	438_L	0.908	1.00
290_N	294_I	0.907	1.00
261_A	283_L	0.906	1.00
180_L	184_F	0.904	1.00
420_Y	424_W	0.900	1.00
64_S	398_P	0.897	1.00
386_M	405_N	0.893	1.00
226_A	236_I	0.893	1.00
433_I	440_I	0.892	1.00
143_L	357_L	0.891	1.00
248_T	252_V	0.891	1.00
61_E	64_S	0.889	1.00
343_R	347_F	0.889	1.00
203_V	206_A	0.888	1.00
18_L	247_A	0.888	1.00
111_M	301_F	0.888	1.00
102_V	367_A	0.883	1.00
34_A	41_A	0.883	1.00
145_I	305_S	0.880	1.00
221_S	314_T	0.879	1.00
288_N	292_L	0.877	1.00
220_Q	224_N	0.873	1.00
55_I	415_A	0.868	1.00
169_I	250_I	0.867	1.00
427_T	441_Y	0.865	1.00
77_Q	325_N	0.863	1.00
83_F	87_I	0.863	1.00
275_N	279_P	0.858	1.00
332_F	344_Q	0.853	1.00
278_S	281_A	0.851	1.00
427_T	440_I	0.849	1.00
84_I	380_T	0.846	1.00
404_L	407_I	0.844	1.00
412_F	415_A	0.841	1.00
415_A	419_L	0.841	1.00
54_F	407_I	0.837	1.00
148_L	151_Y	0.831	1.00
431_L	434_I	0.831	1.00
350_L	354_F	0.828	1.00
188_N	192_G	0.827	1.00
289_I	292_L	0.822	1.00
138_F	141_V	0.822	1.00
389_R	393_K	0.820	1.00
70_G	74_K	0.818	1.00
256_I	260_G	0.817	1.00
386_M	408_A	0.816	1.00
107_S	305_S	0.813	1.00
176_I	257_A	0.812	1.00
107_S	304_P	0.811	1.00
436_I	440_I	0.807	1.00
275_N	278_S	0.807	1.00
14_M	239_A	0.805	1.00
10_T	239_A	0.800	1.00
62_L	385_V	0.795	1.00
194_S	197_P	0.794	1.00
319_I	348_F	0.786	1.00
237_P	240_V	0.785	1.00
4_L	320_Y	0.785	1.00
369_I	373_A	0.780	1.00
233_G	398_P	0.780	1.00
112_S	135_G	0.776	1.00
90_W	328_M	0.774	1.00
433_I	436_I	0.772	1.00
108_V	139_A	0.772	1.00
417_L	420_Y	0.767	1.00
186_G	189_F	0.767	1.00
76_T	384_T	0.766	1.00
175_T	284_A	0.765	1.00
11_F	159_K	0.765	1.00
419_L	422_A	0.764	1.00
196_A	203_V	0.763	1.00
395_L	398_P	0.762	1.00
146_Y	309_I	0.761	1.00
26_W	254_L	0.760	1.00
41_A	255_Q	0.759	1.00
393_K	396_Y	0.758	1.00
146_Y	312_T	0.757	1.00
7_R	154_V	0.755	1.00
53_L	57_L	0.755	1.00
189_F	259_I	0.755	1.00
53_L	241_V	0.753	1.00
23_G	27_L	0.751	1.00
386_M	390_R	0.750	1.00
401_L	407_I	0.747	1.00
42_I	259_I	0.747	1.00
97_V	352_V	0.746	1.00
328_M	332_F	0.744	1.00
390_R	394_D	0.744	1.00
291_W	294_I	0.744	1.00
436_I	439_P	0.742	1.00
168_K	303_S	0.742	1.00
431_L	437_G	0.741	1.00
190_T	194_S	0.740	1.00
43_I	46_V	0.735	1.00
158_S	162_S	0.734	1.00
434_I	438_L	0.733	1.00
405_N	408_A	0.728	1.00
439_P	442_F	0.727	1.00
428_G	433_I	0.726	1.00
81_G	445_Q	0.724	1.00
20_S	310_T	0.722	1.00
95_A	374_T	0.721	1.00
39_P	259_I	0.720	1.00
70_G	73_V	0.717	1.00
136_L	357_L	0.716	1.00
438_L	441_Y	0.714	1.00
284_A	287_L	0.714	1.00
384_T	388_L	0.714	1.00
54_F	58_S	0.714	1.00
102_V	214_F	0.711	1.00
332_F	345_A	0.711	1.00
30_A	255_Q	0.706	1.00
58_S	401_L	0.704	1.00
99_V	370_I	0.704	1.00
22_I	168_K	0.704	1.00
140_S	358_F	0.703	1.00
441_Y	445_Q	0.701	1.00
430_V	433_I	0.699	1.00
404_L	409_P	0.699	1.00
99_V	102_V	0.699	1.00
105_V	366_L	0.698	1.00
426_L	431_L	0.697	1.00
52_I	219_F	0.696	1.00
51_V	54_F	0.693	1.00
151_Y	336_H	0.693	1.00
62_L	75_Y	0.692	1.00
418_V	422_A	0.692	1.00
411_G	414_F	0.692	1.00
43_I	203_V	0.692	1.00
92_N	96_I	0.689	1.00
279_P	282_D	0.688	1.00
427_T	444_Y	0.686	1.00
351_I	354_F	0.685	1.00
46_V	50_V	0.685	1.00
113_S	297_Y	0.683	1.00
189_F	260_G	0.682	1.00
152_W	156_L	0.681	1.00
176_I	254_L	0.680	1.00
316_S	345_A	0.679	1.00
22_I	27_L	0.679	1.00
430_V	437_G	0.678	1.00
186_G	260_G	0.675	1.00
242_G	245_F	0.674	1.00
101_P	366_L	0.673	1.00
280_F	284_A	0.670	1.00
142_L	308_G	0.669	1.00
442_F	445_Q	0.667	1.00
136_L	139_A	0.667	1.00
199_G	203_V	0.665	1.00
194_S	198_N	0.665	1.00
19_G	165_T	0.662	1.00
32_R	364_G	0.662	1.00
420_Y	423_R	0.662	1.00
42_I	46_V	0.661	1.00
427_T	433_I	0.661	1.00
167_F	171_I	0.660	1.00
59_Y	381_G	0.659	1.00
151_Y	339_Y	0.659	1.00
98_S	369_I	0.657	1.00
42_I	252_V	0.657	1.00
253_L	257_A	0.656	1.00
54_F	411_G	0.653	1.00
43_I	47_I	0.653	1.00
192_G	196_A	0.652	1.00
114_W	298_A	0.652	1.00
63_G	223_I	0.651	1.00
29_G	367_A	0.651	1.00
433_I	441_Y	0.650	1.00
206_A	209_T	0.650	1.00
180_L	253_L	0.650	1.00
429_Q	433_I	0.650	1.00
73_V	77_Q	0.649	1.00
108_V	135_G	0.648	1.00
217_N	378_Y	0.646	1.00
432_F	439_P	0.645	1.00
108_V	111_M	0.644	1.00
7_R	11_F	0.643	1.00
437_G	444_Y	0.643	1.00
231_N	237_P	0.643	1.00
429_Q	435_L	0.642	1.00
408_A	415_A	0.639	1.00
408_A	411_G	0.638	1.00
337_P	340_G	0.638	1.00
20_S	311_Y	0.638	1.00
132_T	135_G	0.637	1.00
53_L	245_F	0.637	1.00
80_H	384_T	0.637	1.00
44_S	203_V	0.635	1.00
167_F	299_D	0.634	1.00
323_E	332_F	0.634	1.00
355_I	358_F	0.633	1.00
427_T	437_G	0.633	1.00
342_P	345_A	0.632	1.00
40_A	195_I	0.630	1.00
181_F	184_F	0.629	1.00
91_A	377_S	0.629	1.00
445_Q	448_A	0.628	1.00
408_A	425_P	0.628	1.00
101_P	356_F	0.628	1.00
281_A	285_I	0.625	1.00
150_N	346_M	0.625	1.00
199_G	206_A	0.625	1.00
411_G	422_A	0.623	1.00
279_P	284_A	0.623	1.00
49_M	54_F	0.621	1.00
331_I	348_F	0.621	1.00
441_Y	447_K	0.620	1.00
18_L	165_T	0.620	1.00
56_A	219_F	0.618	1.00
435_L	438_L	0.617	1.00
201_A	204_L	0.617	1.00
223_I	240_V	0.615	1.00
427_T	434_I	0.615	1.00
233_G	396_Y	0.614	1.00
79_S	387_T	0.611	1.00
48_G	213_V	0.610	1.00
57_L	407_I	0.609	1.00
441_Y	446_A	0.609	1.00
13_L	225_M	0.609	1.00
312_T	316_S	0.608	1.00
227_G	320_Y	0.607	1.00
21_M	243_S	0.606	1.00
69_A	320_Y	0.606	1.00
65_M	398_P	0.606	1.00
428_G	442_F	0.605	1.00
146_Y	305_S	0.605	1.00
407_I	411_G	0.605	1.00
224_N	314_T	0.604	1.00
317_R	320_Y	0.603	1.00
388_L	392_G	0.601	1.00
284_A	289_I	0.600	1.00
298_A	302_V	0.599	1.00
364_G	367_A	0.599	1.00
430_V	435_L	0.597	1.00
171_I	295_V	0.597	1.00
96_I	311_Y	0.596	1.00
295_V	299_D	0.596	1.00
79_S	388_L	0.596	1.00
246_V	250_I	0.593	1.00
430_V	440_I	0.591	1.00
373_A	377_S	0.591	1.00
114_W	297_Y	0.587	1.00
65_M	393_K	0.585	1.00
437_G	442_F	0.584	1.00
147_F	312_T	0.582	1.00
385_V	389_R	0.581	1.00
30_A	33_A	0.581	1.00
192_G	265_S	0.581	1.00
151_Y	346_M	0.580	1.00
426_L	442_F	0.579	1.00
434_I	437_G	0.578	1.00
280_F	283_L	0.577	1.00
398_P	402_K	0.575	1.00
144_L	147_F	0.574	1.00
111_M	142_L	0.574	1.00
220_Q	378_Y	0.573	1.00
101_P	353_S	0.572	1.00
62_L	79_S	0.571	1.00
433_I	438_L	0.569	1.00
153_T	156_L	0.569	1.00
374_T	377_S	0.569	1.00
276_F	280_F	0.568	1.00
315_T	319_I	0.565	1.00
402_K	406_V	0.564	1.00
103_E	308_G	0.563	1.00
396_Y	400_R	0.563	1.00
440_I	445_Q	0.562	1.00
178_A	289_I	0.562	1.00
33_A	37_A	0.561	1.00
81_G	85_G	0.561	1.00
156_L	159_K	0.561	1.00
426_L	441_Y	0.561	1.00
431_L	440_I	0.560	1.00
409_P	412_F	0.560	1.00
204_L	417_L	0.560	1.00
428_G	437_G	0.560	1.00
45_W	215_A	0.559	1.00
72_M	224_N	0.559	1.00
246_V	253_L	0.557	1.00
170_I	173_G	0.555	1.00
17_G	21_M	0.554	1.00
65_M	392_G	0.554	1.00
72_M	381_G	0.553	1.00
408_A	422_A	0.553	1.00
431_L	446_A	0.551	1.00
428_G	441_Y	0.548	1.00
150_N	313_A	0.548	1.00
444_Y	449_K	0.547	1.00
83_F	441_Y	0.547	1.00
421_W	425_P	0.546	1.00
257_A	260_G	0.546	1.00
48_G	216_F	0.545	1.00
441_Y	444_Y	0.545	1.00
61_E	402_K	0.545	1.00
60_S	64_S	0.545	1.00
72_M	220_Q	0.544	1.00
183_G	260_G	0.541	1.00
6_R	230_K	0.541	1.00
11_F	14_M	0.540	1.00
11_F	166_I	0.540	1.00
62_L	388_L	0.537	1.00
73_V	85_G	0.535	1.00
18_L	21_M	0.535	1.00
97_V	349_N	0.535	1.00
99_V	103_E	0.534	1.00
91_A	376_I	0.533	1.00
36_I	205_T	0.532	1.00
254_L	280_F	0.532	1.00
303_S	306_G	0.532	1.00
73_V	89_G	0.531	1.00
22_I	250_I	0.530	1.00
427_T	432_F	0.530	1.00
97_V	101_P	0.529	1.00
431_L	438_L	0.527	1.00
167_F	302_V	0.527	1.00
32_R	35_Q	0.527	1.00
233_G	238_I	0.527	1.00
432_F	443_Y	0.527	1.00
254_L	258_F	0.524	1.00
294_I	297_Y	0.524	1.00
331_I	335_L	0.523	1.00
143_L	354_F	0.522	1.00
110_Y	300_A	0.522	1.00
14_M	17_G	0.522	1.00
37_A	44_S	0.522	1.00
408_A	419_L	0.522	1.00
336_H	340_G	0.521	1.00
201_A	208_A	0.521	1.00
234_K	237_P	0.521	1.00
156_L	160_A	0.520	1.00
42_I	45_W	0.520	1.00
15_M	165_T	0.520	1.00
145_I	149_L	0.519	1.00
363_W	367_A	0.518	1.00
165_T	168_K	0.517	1.00
9_G	155_N	0.517	1.00
95_A	373_A	0.516	0.99
375_L	415_A	0.516	0.99
192_G	197_P	0.515	0.99
408_A	424_W	0.515	0.99
432_F	437_G	0.514	0.99
57_L	402_K	0.514	0.99
27_L	168_K	0.514	0.99
428_G	435_L	0.512	0.99
98_S	370_I	0.511	0.99
158_S	309_I	0.511	0.99
246_V	249_V	0.507	0.99
379_I	419_L	0.507	0.99
389_R	404_L	0.507	0.99
163_L	167_F	0.507	0.99
112_S	116_W	0.506	0.99
201_A	206_A	0.505	0.99
417_L	424_W	0.505	0.99
104_A	146_Y	0.505	0.99
103_E	304_P	0.504	0.99
142_L	305_S	0.504	0.99
106_A	110_Y	0.504	0.99
36_I	39_P	0.503	0.99
217_N	370_I	0.502	0.99
316_S	349_N	0.501	0.99
8_M	154_V	0.500	0.99
141_V	144_L	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.7737	100	0.375	Contact Map
3giaA	1	0.7941	100	0.407	Contact Map
4djkA	2	0.7811	100	0.43	Contact Map
2jlnA	1	0.7755	99	0.871	Contact Map
3dh4A	3	0.8349	98.6	0.892	Contact Map
2xq2A	2	0.7681	98.5	0.893	Contact Map
4wgvA	2	0.6809	98.2	0.903	Contact Map
4us3A	1	0.7384	96.4	0.929	Contact Map
2a65A	2	0.8089	95.9	0.932	Contact Map
4xp4A	1	0.8275	94.7	0.937	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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