CSBB - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

CSBB - Putative glycosyltransferase CsbB

UniProt:	Q45539	Sequences: MKQGLISIIIPSYNEGYNVKLIHESLKKEFKNIHYDYEIFFINDGSVDDTLQQIKDLAATCSRVKYISFSRNFGKEAAILAGFEHVQGEAVIVMDADLQHPTYLLKEFIKGYEEGYDQVIAQRNRKGDSFVRSLLSSMYYKFINKAVEVDLRDGVGDFRLLSRQAVNALLKLSEGNRFSKGLFCWIGFDQKIVFYENVERKNGTSKWSFSSLFNYGMDGVVSFNHKPLRLCFYTGIFILLLSIIYIIATFVKILTNGISVPGYFTIISAVLFLGGVQLLSLGIIGEYIGRIYYETKKRPHYLIKEANIPNKDLPETNELKSMRRLTKMH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	329 (278)
Sequences:	16243 (12914)
Seq/√Len:	774.5

ECOLI - ARNC GTRB YAIP PGAC YIBD WCAA
BACSU - CSBB YKCC YKOT YDAM EPSH GGAA EPSJ CGED TUAG EPSE GGAB
HALSA - Q9HQQ6 Q9HSB1 Q9HQP8 Q9HQP4 Q9HR08 Q9HQP3 Q9HSC8
SULSO - Q97TY0 Q97W52 Q7LXY2 Q97WK7 Q97UK7 Q97YM4 Q97TZ0 Q7LXF7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
16_G	49_D	5.020	1.00
43_N	68_S	4.452	1.00
163_R	167_N	4.120	1.00
49_D	52_Q	3.411	1.00
7_S	88_G	3.401	1.00
116_Y	191_K	3.079	1.00
54_I	66_Y	3.001	1.00
7_S	38_E	2.839	1.00
51_L	68_S	2.689	1.00
90_A	112_Y	2.589	1.00
111_G	114_E	2.582	1.00
38_E	65_K	2.572	1.00
51_L	55_K	2.567	1.00
20_K	56_D	2.559	1.00
12_S	50_T	2.497	1.00
5_L	89_E	2.428	1.00
43_N	46_S	2.413	1.00
42_I	82_G	2.366	1.00
20_K	53_Q	2.335	1.00
20_K	24_E	2.293	1.00
92_I	160_L	2.237	1.00
165_A	188_F	2.235	1.00
111_G	191_K	2.213	1.00
41_F	54_I	2.212	1.00
51_L	66_Y	2.177	1.00
23_H	57_L	2.075	1.00
5_L	87_Q	2.066	1.00
90_A	160_L	2.003	1.00
52_Q	56_D	1.975	1.00
112_Y	160_L	1.949	1.00
117_D	162_S	1.935	1.00
53_Q	56_D	1.933	1.00
107_E	110_K	1.913	1.00
5_L	36_D	1.900	1.00
38_E	88_G	1.884	1.00
111_G	193_V	1.882	1.00
24_E	57_L	1.858	1.00
49_D	53_Q	1.857	1.00
6_I	109_I	1.856	1.00
107_E	195_Y	1.850	1.00
15_E	96_A	1.848	1.00
92_I	105_L	1.839	1.00
168_A	188_F	1.821	1.00
75_K	79_I	1.816	1.00
90_A	109_I	1.814	1.00
69_F	81_A	1.806	1.00
178_F	182_L	1.795	1.00
7_S	86_V	1.776	1.00
14_N	47_V	1.761	1.00
56_D	60_T	1.757	1.00
7_S	40_F	1.755	1.00
144_N	147_V	1.754	1.00
110_K	114_E	1.745	1.00
108_F	160_L	1.693	1.00
168_A	186_I	1.686	1.00
55_K	68_S	1.675	1.00
33_I	106_K	1.650	1.00
21_L	24_E	1.621	1.00
9_I	82_G	1.593	1.00
129_S	132_R	1.591	1.00
23_H	61_C	1.560	1.00
112_Y	162_S	1.554	1.00
117_D	188_F	1.541	1.00
13_Y	72_N	1.535	1.00
24_E	28_K	1.515	1.00
9_I	42_I	1.497	1.00
83_F	91_V	1.489	1.00
33_I	36_D	1.484	1.00
14_N	46_S	1.447	1.00
83_F	166_V	1.443	1.00
24_E	60_T	1.441	1.00
91_V	166_V	1.435	1.00
141_K	144_N	1.431	1.00
79_I	93_V	1.419	1.00
10_I	22_I	1.413	1.00
67_I	85_H	1.406	1.00
27_K	61_C	1.404	1.00
25_S	103_Y	1.379	1.00
12_S	96_A	1.372	1.00
23_H	41_F	1.369	1.00
43_N	51_L	1.364	1.00
81_A	85_H	1.357	1.00
118_Q	190_Q	1.353	1.00
5_L	88_G	1.349	1.00
38_E	87_Q	1.340	1.00
205_S	208_S	1.339	1.00
164_Q	168_A	1.337	1.00
118_Q	183_F	1.304	1.00
103_Y	107_E	1.290	1.00
42_I	78_A	1.276	1.00
125_R	128_D	1.253	1.00
86_V	163_R	1.237	1.00
6_I	105_L	1.237	1.00
16_G	53_Q	1.230	1.00
211_S	214_N	1.228	1.00
25_S	100_H	1.213	1.00
56_D	59_A	1.211	1.00
141_K	145_K	1.203	1.00
122_Q	194_F	1.195	1.00
211_S	215_Y	1.172	1.00
52_Q	55_K	1.170	1.00
40_F	65_K	1.163	1.00
21_L	201_K	1.151	1.00
10_I	96_A	1.123	1.00
130_F	133_S	1.119	1.00
132_R	135_L	1.112	1.00
21_L	25_S	1.108	1.00
8_I	105_L	1.099	1.00
44_D	72_N	1.094	1.00
19_V	53_Q	1.090	1.00
44_D	74_G	1.086	1.00
82_G	86_V	1.080	1.00
162_S	165_A	1.074	1.00
12_S	41_F	1.072	1.00
91_V	163_R	1.064	1.00
84_E	170_L	1.053	1.00
25_S	99_Q	1.052	1.00
65_K	85_H	1.049	1.00
100_H	197_N	1.047	1.00
8_I	92_I	1.041	1.00
224_N	227_P	1.040	1.00
130_F	134_L	1.038	1.00
165_A	183_F	1.034	1.00
81_A	84_E	1.025	1.00
108_F	121_A	1.023	1.00
154_G	159_R	1.016	1.00
193_V	196_E	1.014	1.00
53_Q	57_L	1.002	1.00
100_H	104_L	1.000	1.00
23_H	64_V	0.995	1.00
94_M	100_H	0.995	1.00
22_I	26_L	0.988	1.00
27_K	63_R	0.987	1.00
37_Y	63_R	0.986	1.00
164_Q	167_N	0.984	1.00
168_A	171_K	0.982	1.00
248_A	252_K	0.980	1.00
212_L	215_Y	0.973	1.00
90_A	162_S	0.969	1.00
35_Y	113_E	0.968	1.00
20_K	60_T	0.963	1.00
131_V	135_L	0.962	1.00
109_I	113_E	0.961	1.00
134_L	138_M	0.961	1.00
111_G	119_V	0.947	1.00
67_I	81_A	0.942	1.00
88_G	163_R	0.940	1.00
123_R	157_D	0.931	1.00
75_K	95_D	0.925	1.00
235_G	239_L	0.921	1.00
20_K	57_L	0.915	1.00
110_K	113_E	0.912	1.00
23_H	27_K	0.908	1.00
174_E	177_R	0.907	1.00
239_L	242_S	0.907	1.00
29_E	106_K	0.906	1.00
200_R	203_G	0.903	1.00
104_L	107_E	0.902	1.00
143_I	147_V	0.901	1.00
83_F	93_V	0.895	1.00
104_L	158_F	0.890	1.00
252_K	256_N	0.885	1.00
28_K	102_T	0.880	1.00
139_Y	143_I	0.879	1.00
161_L	183_F	0.878	1.00
25_S	198_V	0.877	1.00
138_M	141_K	0.873	1.00
215_Y	219_G	0.873	1.00
232_F	235_G	0.872	1.00
133_S	136_S	0.868	1.00
40_F	86_V	0.866	1.00
58_A	64_V	0.862	1.00
215_Y	218_D	0.859	1.00
25_S	28_K	0.853	1.00
12_S	15_E	0.849	1.00
217_M	221_V	0.845	1.00
13_Y	47_V	0.837	1.00
216_G	219_G	0.836	1.00
18_N	201_K	0.833	1.00
161_L	166_V	0.832	1.00
21_L	99_Q	0.829	1.00
80_L	84_E	0.828	1.00
25_S	29_E	0.824	1.00
144_N	148_E	0.822	1.00
41_F	64_V	0.821	1.00
132_R	136_S	0.819	1.00
140_Y	143_I	0.814	1.00
65_K	87_Q	0.813	1.00
251_V	255_T	0.809	1.00
275_G	278_L	0.805	1.00
120_I	123_R	0.802	1.00
57_L	61_C	0.802	1.00
262_G	265_T	0.799	1.00
19_V	41_F	0.797	1.00
10_I	41_F	0.796	1.00
10_I	26_L	0.793	1.00
8_I	26_L	0.793	1.00
38_E	86_V	0.792	1.00
106_K	110_K	0.792	1.00
89_E	164_Q	0.790	1.00
218_D	221_V	0.789	1.00
15_E	18_N	0.787	1.00
117_D	164_Q	0.786	1.00
271_L	275_G	0.786	1.00
133_S	137_S	0.781	1.00
271_L	274_G	0.780	1.00
121_A	158_F	0.779	1.00
226_K	229_R	0.777	1.00
281_L	285_G	0.773	1.00
5_L	38_E	0.770	1.00
273_L	277_Q	0.769	1.00
18_N	22_I	0.768	1.00
256_N	259_S	0.765	1.00
231_C	235_G	0.764	1.00
269_A	273_L	0.759	1.00
124_N	127_G	0.747	1.00
14_N	48_D	0.745	1.00
225_H	229_R	0.741	1.00
183_F	188_F	0.741	1.00
39_I	64_V	0.741	1.00
111_G	115_G	0.734	1.00
29_E	33_I	0.734	1.00
12_S	19_V	0.733	1.00
107_E	111_G	0.730	1.00
19_V	50_T	0.728	1.00
7_S	87_Q	0.728	1.00
37_Y	105_L	0.727	1.00
272_F	276_V	0.727	1.00
131_V	134_L	0.726	1.00
7_S	163_R	0.725	1.00
46_S	50_T	0.724	1.00
22_I	96_A	0.722	1.00
58_A	61_C	0.722	1.00
33_I	37_Y	0.720	1.00
22_I	25_S	0.718	1.00
214_N	218_D	0.717	1.00
61_C	64_V	0.713	1.00
178_F	181_G	0.712	1.00
26_L	39_I	0.710	1.00
142_F	146_A	0.709	1.00
98_L	200_R	0.708	1.00
223_F	227_P	0.708	1.00
249_T	252_K	0.702	1.00
135_L	138_M	0.701	1.00
224_N	228_L	0.699	1.00
162_S	188_F	0.698	1.00
253_I	256_N	0.697	1.00
108_F	196_E	0.696	1.00
141_K	147_V	0.695	1.00
55_K	59_A	0.694	1.00
34_H	37_Y	0.692	1.00
86_V	91_V	0.691	1.00
92_I	104_L	0.690	1.00
19_V	54_I	0.689	1.00
112_Y	119_V	0.687	1.00
212_L	216_G	0.687	1.00
142_F	147_V	0.685	1.00
225_H	228_L	0.684	1.00
55_K	58_A	0.683	1.00
141_K	146_A	0.681	1.00
69_F	72_N	0.681	1.00
10_I	94_M	0.677	1.00
222_S	225_H	0.673	1.00
140_Y	144_N	0.669	1.00
10_I	39_I	0.666	1.00
240_L	244_I	0.666	1.00
275_G	285_G	0.665	1.00
9_I	86_V	0.662	1.00
75_K	156_G	0.660	1.00
109_I	160_L	0.660	1.00
274_G	278_L	0.659	1.00
246_I	249_T	0.658	1.00
16_G	48_D	0.653	1.00
98_L	198_V	0.652	1.00
245_Y	249_T	0.652	1.00
276_V	280_S	0.651	1.00
281_L	284_I	0.650	1.00
36_D	63_R	0.650	1.00
54_I	58_A	0.650	1.00
111_G	116_Y	0.649	1.00
222_S	226_K	0.649	1.00
239_L	243_I	0.648	1.00
13_Y	45_G	0.648	1.00
242_S	272_F	0.647	1.00
139_Y	146_A	0.647	1.00
83_F	86_V	0.646	1.00
276_V	279_L	0.642	1.00
261_P	264_F	0.640	1.00
129_S	136_S	0.639	1.00
6_I	35_Y	0.637	1.00
16_G	52_Q	0.636	1.00
191_K	194_F	0.636	1.00
124_N	196_E	0.633	1.00
19_V	57_L	0.632	1.00
213_F	217_M	0.631	1.00
58_A	66_Y	0.627	1.00
268_S	271_L	0.626	1.00
73_F	77_A	0.626	1.00
272_F	279_L	0.625	1.00
108_F	158_F	0.625	1.00
211_S	218_D	0.620	1.00
209_F	212_L	0.616	1.00
70_S	73_F	0.616	1.00
19_V	24_E	0.616	1.00
76_E	80_L	0.615	1.00
27_K	64_V	0.611	1.00
236_I	240_L	0.609	1.00
165_A	168_A	0.607	1.00
256_N	260_V	0.606	1.00
89_E	163_R	0.606	1.00
101_P	104_L	0.606	1.00
209_F	213_F	0.602	1.00
272_F	275_G	0.600	1.00
270_V	273_L	0.599	1.00
116_Y	119_V	0.598	1.00
138_M	147_V	0.598	1.00
266_I	269_A	0.597	1.00
70_S	81_A	0.597	1.00
106_K	109_I	0.596	1.00
222_S	229_R	0.595	1.00
15_E	50_T	0.595	1.00
132_R	137_S	0.594	1.00
5_L	37_Y	0.593	1.00
51_L	54_I	0.593	1.00
93_V	159_R	0.590	1.00
122_Q	192_I	0.590	1.00
117_D	189_D	0.588	1.00
107_E	193_V	0.588	1.00
279_L	282_G	0.586	1.00
8_I	94_M	0.584	1.00
258_I	261_P	0.584	1.00
173_S	178_F	0.583	1.00
14_N	50_T	0.579	1.00
268_S	272_F	0.579	1.00
57_L	60_T	0.578	1.00
26_L	100_H	0.577	1.00
229_R	232_F	0.575	1.00
233_Y	236_I	0.574	1.00
134_L	137_S	0.574	1.00
103_Y	106_K	0.573	1.00
230_L	235_G	0.571	1.00
247_I	251_V	0.571	1.00
143_I	148_E	0.568	1.00
34_H	109_I	0.567	1.00
19_V	96_A	0.566	1.00
277_Q	281_L	0.565	1.00
264_F	268_S	0.565	1.00
18_N	96_A	0.564	1.00
74_G	97_D	0.564	1.00
116_Y	189_D	0.564	1.00
238_I	242_S	0.561	1.00
275_G	279_L	0.560	1.00
131_V	136_S	0.559	1.00
50_T	96_A	0.559	1.00
222_S	227_P	0.558	1.00
44_D	95_D	0.558	1.00
89_E	162_S	0.556	1.00
120_I	190_Q	0.554	1.00
173_S	182_L	0.552	1.00
274_G	277_Q	0.551	1.00
184_C	190_Q	0.550	1.00
105_L	160_L	0.550	1.00
139_Y	144_N	0.548	1.00
15_E	75_K	0.546	1.00
169_L	183_F	0.545	1.00
224_N	229_R	0.545	1.00
11_P	78_A	0.545	1.00
140_Y	148_E	0.544	1.00
129_S	134_L	0.542	1.00
263_Y	267_I	0.542	1.00
55_K	66_Y	0.542	1.00
227_P	230_L	0.540	1.00
174_E	178_F	0.540	1.00
282_G	285_G	0.538	1.00
120_I	192_I	0.538	1.00
255_T	258_I	0.537	1.00
244_I	248_A	0.536	1.00
100_H	158_F	0.536	1.00
139_Y	142_F	0.536	1.00
104_L	108_F	0.535	1.00
143_I	146_A	0.534	1.00
223_F	226_K	0.532	1.00
261_P	265_T	0.531	1.00
145_K	148_E	0.531	1.00
69_F	73_F	0.531	1.00
108_F	112_Y	0.530	1.00
14_N	43_N	0.530	1.00
130_F	135_L	0.530	1.00
119_V	193_V	0.528	1.00
25_S	98_L	0.528	1.00
231_C	234_T	0.528	1.00
40_F	85_H	0.527	1.00
50_T	54_I	0.526	1.00
131_V	137_S	0.522	1.00
13_Y	43_N	0.520	1.00
45_G	72_N	0.520	1.00
266_I	270_V	0.518	1.00
212_L	219_G	0.516	1.00
5_L	35_Y	0.514	1.00
210_S	213_F	0.514	1.00
40_F	82_G	0.513	1.00
80_L	173_S	0.513	1.00
233_Y	237_F	0.512	1.00
92_I	108_F	0.511	1.00
145_K	149_V	0.511	1.00
271_L	279_L	0.510	1.00
17_Y	53_Q	0.510	1.00
141_K	148_E	0.510	1.00
139_Y	147_V	0.508	1.00
269_A	282_G	0.508	1.00
210_S	214_N	0.507	1.00
234_T	238_I	0.506	1.00
142_F	145_K	0.505	1.00
8_I	37_Y	0.505	1.00
179_S	183_F	0.503	1.00
138_M	146_A	0.502	1.00
273_L	276_V	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4p02A	1	0.9605	100	0.45	Contact Map
2z86A	2	0.7325	100	0.478	Contact Map
3bcvA	2	0.5258	100	0.486	Contact Map
2d7iA	1	0.8663	100	0.497	Contact Map
1qg8A	1	0.6383	100	0.502	Contact Map
1xhbA	1	0.9544	100	0.504	Contact Map
3l7iA	4	0.0912	100	0.505	Contact Map
3ckjA	2	0.7538	100	0.519	Contact Map
2bo4A	4	0.8632	100	0.521	Contact Map
4fixA	3	0.9605	100	0.521	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0125 seconds.