RNJ1 - BACSU - GREMLIN Contacts

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RNJ1 - Ribonuclease J1

UniProt:	Q45493	Sequences: MKFVKNDQTAVFALGGLGEIGKNTYAVQFQDEIVLIDAGIKFPEDELLGIDYVIPDYTYLVKNEDKIKGLFITHGHEDHIGGIPYLLRQVNIPVYGGKLAIGLLRNKLEEHGLLRQTKLNIIGEDDIVKFRKTAVSFFRTTHSIPDSYGIVVKTPPGNIVHTGDFKFDFTPVGEPANLTKMAEIGKEGVLCLLSDSTNSENPEFTMSERRVGESIHDIFRKVDGRIIFATFASNIHRLQQVIEAAVQNGRKVAVFGRSMESAIEIGQTLGYINCPKNTFIEHNEINRMPANKVTILCTGSQGEPMAALSRIANGTHRQISINPGDTVVFSSSPIPGNTISVSRTINQLYRAGAEVIHGPLNDIHTSGHGGQEEQKLMLRLIKPKFFMPIHGEYRMQKMHVKLATDCGIPEENCFIMDNGEVLALKGDEASVAGKIPSGSVYIDGSGIGDIGNIVLRDRRILSEEGLVIVVVSIDMDDFKISAGPDLISRGFVYMRESGDLINDAQELISNHLQKVMERKTTQWSEIKNEITDTLAPFLYEKTKRRPMILPIIMEV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	555 (542)
Sequences:	3042 (1842)
Seq/√Len:	79.1

BACSU - RNJ1 RNJ2
HALSA - Q9HS54 RNJ
SULSO - Q7LYL5 Q980D0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
32_E	68_K	5.947	1.00
72_I	104_L	5.028	1.00
70_L	83_I	4.655	1.00
219_F	226_I	4.458	1.00
97_G	148_Y	4.132	1.00
153_K	187_E	3.875	1.00
61_V	89_Q	3.805	1.00
290_A	322_N	3.528	1.00
27_V	36_I	3.523	1.00
288_M	293_V	3.457	1.00
191_C	387_M	3.362	1.00
151_V	158_N	3.271	1.00
9_T	159_I	3.223	1.00
216_H	247_Q	3.088	1.00
280_I	288_M	3.020	1.00
245_A	294_T	2.907	1.00
321_I	353_A	2.834	1.00
138_F	149_G	2.828	1.00
127_I	134_A	2.787	1.00
253_A	285_I	2.776	1.00
416_M	422_L	2.727	1.00
96_G	104_L	2.724	1.00
153_K	158_N	2.697	1.00
400_V	404_T	2.646	1.00
35_L	67_I	2.573	1.00
129_K	134_A	2.563	1.00
414_F	422_L	2.548	1.00
36_I	152_V	2.522	1.00
32_E	132_K	2.501	1.00
63_N	66_K	2.500	1.00
387_M	422_L	2.490	1.00
60_L	67_I	2.454	1.00
123_G	126_D	2.421	1.00
386_F	399_H	2.351	1.00
228_F	241_V	2.342	1.00
36_I	73_T	2.336	1.00
372_E	375_K	2.335	1.00
72_I	100_A	2.331	1.00
242_I	252_V	2.316	1.00
192_L	381_I	2.310	1.00
205_T	370_G	2.287	1.00
10_A	28_Q	2.281	1.00
33_I	60_L	2.276	1.00
57_Y	86_L	2.267	1.00
404_T	410_E	2.267	1.00
31_D	66_K	2.264	1.00
183_E	186_K	2.255	1.00
254_V	263_I	2.252	1.00
71_F	150_I	2.242	1.00
194_S	378_L	2.241	1.00
35_L	60_L	2.224	1.00
162_T	377_M	2.214	1.00
33_I	67_I	2.209	1.00
374_Q	402_L	2.208	1.00
11_V	191_C	2.191	1.00
96_G	101_I	2.186	1.00
186_K	382_K	2.174	1.00
134_A	153_K	2.162	1.00
312_A	347_Q	2.139	1.00
72_I	96_G	2.122	1.00
281_E	284_E	2.100	1.00
70_L	92_I	2.091	1.00
400_V	413_C	2.084	1.00
246_V	275_P	2.074	1.00
219_F	294_T	2.042	1.00
151_V	184_I	2.032	1.00
160_V	381_I	2.029	1.00
36_I	150_I	1.964	1.00
101_I	119_L	1.951	1.00
136_S	180_K	1.933	1.00
274_C	279_F	1.924	1.00
249_G	292_K	1.919	1.00
386_F	403_A	1.866	1.00
137_F	150_I	1.850	1.00
88_R	111_H	1.829	1.00
216_H	248_N	1.826	1.00
401_K	404_T	1.802	1.00
224_G	326_T	1.785	1.00
350_R	417_D	1.779	1.00
421_V	435_I	1.770	1.00
32_E	66_K	1.766	1.00
34_V	71_F	1.759	1.00
504_A	534_L	1.738	1.00
480_I	483_G	1.736	1.00
218_I	328_V	1.731	1.00
12_F	421_V	1.703	1.00
29_F	155_P	1.695	1.00
24_T	35_L	1.694	1.00
241_V	294_T	1.690	1.00
122_I	137_F	1.688	1.00
181_M	381_I	1.682	1.00
167_F	176_A	1.674	1.00
386_F	408_I	1.670	1.00
165_F	194_S	1.669	1.00
140_T	147_S	1.651	1.00
190_L	384_K	1.643	1.00
378_L	408_I	1.639	1.00
194_S	399_H	1.629	1.00
289_P	292_K	1.626	1.00
83_I	94_V	1.624	1.00
467_V	538_L	1.619	1.00
34_V	133_T	1.618	1.00
284_E	287_R	1.614	1.00
71_F	135_V	1.595	1.00
400_V	415_I	1.595	1.00
194_S	386_F	1.590	1.00
160_V	192_L	1.586	1.00
503_D	541_K	1.578	1.00
61_V	64_E	1.576	1.00
425_K	428_E	1.573	1.00
180_K	183_E	1.560	0.99
511_H	533_T	1.559	0.99
421_V	433_G	1.539	0.99
98_K	121_I	1.536	0.99
421_V	432_A	1.531	0.99
8_Q	423_A	1.526	0.99
202_P	371_Q	1.519	0.99
71_F	130_F	1.516	0.99
199_S	374_Q	1.516	0.99
371_Q	402_L	1.508	0.99
28_Q	66_K	1.488	0.99
199_S	398_M	1.486	0.99
135_V	150_I	1.485	0.99
217_D	221_K	1.481	0.99
27_V	152_V	1.466	0.99
285_I	293_V	1.465	0.99
469_V	534_L	1.464	0.99
17_L	416_M	1.461	0.99
70_L	86_L	1.459	0.99
106_N	265_I	1.455	0.99
267_Q	276_K	1.453	0.99
189_V	381_I	1.445	0.99
26_A	33_I	1.432	0.99
34_V	135_V	1.426	0.99
36_I	161_H	1.414	0.99
264_E	268_T	1.414	0.99
178_L	182_A	1.413	0.99
222_V	326_T	1.411	0.99
244_A	248_N	1.403	0.99
69_G	130_F	1.402	0.99
507_L	511_H	1.395	0.99
311_I	319_I	1.391	0.99
34_V	68_K	1.379	0.99
378_L	386_F	1.376	0.99
169_F	379_R	1.371	0.99
472_S	482_A	1.370	0.99
285_I	288_M	1.369	0.99
404_T	413_C	1.368	0.99
509_S	513_Q	1.342	0.98
160_V	184_I	1.335	0.98
136_S	153_K	1.333	0.98
14_L	26_A	1.326	0.98
246_V	278_T	1.323	0.98
243_E	273_N	1.317	0.98
72_I	83_I	1.312	0.98
212_G	240_Q	1.307	0.98
87_L	108_L	1.303	0.98
379_R	406_C	1.303	0.98
530_I	533_T	1.302	0.98
235_I	262_A	1.302	0.98
57_Y	90_V	1.300	0.98
102_G	269_L	1.293	0.98
252_V	278_T	1.293	0.98
101_I	121_I	1.287	0.98
223_D	291_N	1.272	0.98
58_T	61_V	1.269	0.98
154_T	157_G	1.269	0.98
97_G	100_A	1.262	0.98
122_I	148_Y	1.256	0.98
138_F	160_V	1.253	0.98
306_A	309_S	1.251	0.98
196_S	399_H	1.243	0.97
398_M	401_K	1.243	0.97
472_S	553_M	1.242	0.97
511_H	529_E	1.240	0.97
15_G	19_E	1.237	0.97
205_T	365_T	1.237	0.97
283_N	318_Q	1.236	0.97
457_D	489_R	1.234	0.97
8_Q	425_K	1.229	0.97
176_A	181_M	1.226	0.97
76_H	368_H	1.222	0.97
128_V	135_V	1.219	0.97
502_N	505_Q	1.217	0.97
409_P	412_N	1.216	0.97
288_M	292_K	1.214	0.97
79_H	390_H	1.209	0.97
27_V	159_I	1.202	0.97
280_I	284_E	1.202	0.97
83_I	92_I	1.198	0.97
74_H	142_H	1.191	0.97
138_F	180_K	1.191	0.97
26_A	60_L	1.190	0.97
47_L	53_V	1.186	0.97
378_L	399_H	1.181	0.96
140_T	181_M	1.178	0.96
28_Q	59_Y	1.176	0.96
416_M	431_V	1.167	0.96
231_F	390_H	1.164	0.96
500_L	538_L	1.163	0.96
274_C	277_N	1.163	0.96
414_F	429_A	1.160	0.96
280_I	293_V	1.160	0.96
210_R	213_E	1.159	0.96
239_Q	243_E	1.157	0.96
75_G	103_L	1.155	0.96
504_A	538_L	1.153	0.96
158_N	187_E	1.151	0.96
204_F	372_E	1.150	0.96
332_S	341_V	1.149	0.96
11_V	193_L	1.147	0.96
197_T	390_H	1.142	0.96
199_S	402_L	1.140	0.96
17_L	418_N	1.136	0.96
80_I	103_L	1.136	0.96
124_E	148_Y	1.132	0.96
9_T	29_F	1.131	0.96
231_F	336_G	1.125	0.95
179_T	182_A	1.124	0.95
34_V	130_F	1.123	0.95
183_E	187_E	1.122	0.95
218_I	356_I	1.119	0.95
122_I	128_V	1.107	0.95
257_R	310_R	1.080	0.94
470_V	551_I	1.079	0.94
139_R	146_D	1.076	0.94
27_V	161_H	1.073	0.94
79_H	164_D	1.071	0.94
267_Q	277_N	1.070	0.94
508_I	530_I	1.067	0.94
321_I	327_V	1.065	0.94
500_L	542_T	1.064	0.94
106_N	261_S	1.063	0.94
33_I	59_Y	1.063	0.94
29_F	132_K	1.062	0.94
73_T	161_H	1.062	0.94
435_I	438_G	1.061	0.94
191_C	424_L	1.057	0.94
272_I	275_P	1.056	0.94
76_H	142_H	1.052	0.93
71_F	128_V	1.048	0.93
263_I	296_L	1.046	0.93
130_F	133_T	1.041	0.93
254_V	279_F	1.032	0.93
345_I	355_V	1.028	0.93
471_V	512_L	1.027	0.93
377_M	381_I	1.026	0.93
333_P	341_V	1.023	0.92
486_L	504_A	1.021	0.92
253_A	280_I	1.021	0.92
78_D	368_H	1.021	0.92
354_E	401_K	1.017	0.92
501_I	504_A	1.017	0.92
135_V	152_V	1.014	0.92
420_E	431_V	1.009	0.92
147_S	163_G	1.009	0.92
74_H	79_H	1.009	0.92
212_G	244_A	1.005	0.92
458_R	465_G	1.004	0.92
34_V	69_G	1.003	0.92
193_L	389_I	1.002	0.92
515_V	520_T	0.999	0.91
516_M	520_T	0.996	0.91
26_A	35_L	0.995	0.91
140_T	176_A	0.994	0.91
385_F	424_L	0.990	0.91
478_F	516_M	0.990	0.91
58_T	436_P	0.983	0.91
127_I	136_S	0.979	0.91
396_Q	415_I	0.979	0.91
506_E	509_S	0.979	0.91
25_Y	389_I	0.978	0.91
306_A	329_F	0.973	0.90
165_F	374_Q	0.972	0.90
100_A	239_Q	0.971	0.90
30_Q	132_K	0.969	0.90
216_H	220_R	0.967	0.90
40_I	52_Y	0.963	0.90
10_A	421_V	0.956	0.90
222_V	226_I	0.953	0.89
124_E	177_N	0.952	0.89
13_A	25_Y	0.950	0.89
197_T	231_F	0.948	0.89
58_T	62_K	0.946	0.89
534_L	548_I	0.944	0.89
507_L	530_I	0.942	0.89
149_G	160_V	0.939	0.89
528_N	532_D	0.936	0.89
446_G	449_D	0.935	0.89
11_V	387_M	0.929	0.88
136_S	151_V	0.926	0.88
167_F	377_M	0.924	0.88
167_F	178_L	0.923	0.88
28_Q	33_I	0.921	0.88
237_R	367_G	0.921	0.88
238_L	263_I	0.919	0.88
485_D	495_R	0.914	0.87
182_A	380_L	0.914	0.87
528_N	531_T	0.908	0.87
491_F	542_T	0.908	0.87
515_V	526_I	0.908	0.87
70_L	94_V	0.906	0.87
508_I	511_H	0.905	0.87
32_E	131_R	0.903	0.87
72_I	101_I	0.903	0.87
11_V	25_Y	0.895	0.86
19_E	418_N	0.893	0.86
334_I	337_N	0.892	0.86
215_I	219_F	0.890	0.86
112_G	117_T	0.889	0.86
102_G	268_T	0.889	0.86
301_Q	337_N	0.887	0.86
153_K	184_I	0.886	0.86
255_F	311_I	0.883	0.86
78_D	197_T	0.881	0.85
446_G	451_G	0.880	0.85
535_A	545_R	0.879	0.85
20_I	197_T	0.879	0.85
12_F	26_A	0.877	0.85
75_G	144_I	0.876	0.85
255_F	319_I	0.875	0.85
507_L	537_F	0.873	0.85
492_V	500_L	0.873	0.85
74_H	368_H	0.867	0.84
12_F	59_Y	0.867	0.84
216_H	244_A	0.867	0.84
408_I	412_N	0.866	0.84
227_I	297_C	0.864	0.84
64_E	67_I	0.863	0.84
74_H	78_D	0.863	0.84
87_L	94_V	0.861	0.84
140_T	149_G	0.861	0.84
525_E	529_E	0.860	0.84
157_G	190_L	0.859	0.84
385_F	414_F	0.854	0.84
25_Y	36_I	0.852	0.83
280_I	285_I	0.847	0.83
178_L	181_M	0.845	0.83
508_I	512_L	0.843	0.83
309_S	313_N	0.841	0.83
203_E	372_E	0.840	0.83
492_V	542_T	0.839	0.82
138_F	184_I	0.838	0.82
105_R	121_I	0.837	0.82
200_E	394_R	0.836	0.82
79_H	197_T	0.835	0.82
511_H	530_I	0.831	0.82
182_A	185_G	0.830	0.82
444_G	448_G	0.830	0.82
417_D	420_E	0.829	0.82
142_H	368_H	0.828	0.82
22_K	333_P	0.827	0.82
11_V	27_V	0.826	0.82
470_V	553_M	0.826	0.82
309_S	344_T	0.825	0.81
38_A	57_Y	0.819	0.81
221_K	469_V	0.817	0.81
529_E	533_T	0.815	0.81
314_G	320_S	0.814	0.81
24_T	57_Y	0.814	0.81
27_V	133_T	0.813	0.80
160_V	189_V	0.813	0.80
64_E	91_N	0.812	0.80
139_R	174_E	0.812	0.80
480_I	516_M	0.812	0.80
9_T	155_P	0.811	0.80
244_A	247_Q	0.811	0.80
22_K	332_S	0.811	0.80
417_D	434_K	0.809	0.80
453_I	456_R	0.808	0.80
507_L	533_T	0.808	0.80
471_V	530_I	0.807	0.80
159_I	193_L	0.807	0.80
503_D	537_F	0.803	0.80
12_F	435_I	0.801	0.79
32_E	69_G	0.800	0.79
226_I	328_V	0.795	0.79
33_I	66_K	0.794	0.79
71_F	131_R	0.794	0.79
399_H	403_A	0.792	0.79
280_I	287_R	0.789	0.78
423_A	432_A	0.785	0.78
19_E	22_K	0.784	0.78
468_I	485_D	0.781	0.78
204_F	376_L	0.780	0.78
273_N	276_K	0.779	0.78
113_L	117_T	0.778	0.77
96_G	119_L	0.777	0.77
10_A	423_A	0.777	0.77
423_A	430_S	0.777	0.77
495_R	532_D	0.776	0.77
313_N	347_Q	0.776	0.77
192_L	386_F	0.776	0.77
532_D	539_Y	0.775	0.77
347_Q	350_R	0.775	0.77
138_F	181_M	0.775	0.77
384_K	412_N	0.773	0.77
98_K	123_G	0.771	0.77
537_F	541_K	0.769	0.77
178_L	377_M	0.769	0.77
163_G	197_T	0.768	0.77
203_E	370_G	0.768	0.77
506_E	510_N	0.767	0.76
100_A	148_Y	0.767	0.76
98_K	271_Y	0.767	0.76
298_T	303_E	0.763	0.76
194_S	408_I	0.762	0.76
106_N	109_E	0.761	0.76
314_G	351_A	0.760	0.76
162_T	192_L	0.758	0.76
97_G	146_D	0.757	0.76
188_G	384_K	0.756	0.75
219_F	248_N	0.754	0.75
68_K	132_K	0.752	0.75
449_D	453_I	0.751	0.75
311_I	316_H	0.750	0.75
9_T	27_V	0.749	0.75
397_K	400_V	0.748	0.75
492_V	495_R	0.747	0.75
242_I	246_V	0.747	0.75
129_K	132_K	0.747	0.75
539_Y	543_K	0.744	0.74
24_T	38_A	0.742	0.74
274_C	278_T	0.737	0.74
194_S	377_M	0.737	0.74
77_E	107_K	0.735	0.73
444_G	447_I	0.735	0.73
201_N	370_G	0.734	0.73
108_L	113_L	0.734	0.73
76_H	79_H	0.734	0.73
213_E	217_D	0.733	0.73
151_V	190_L	0.732	0.73
164_D	390_H	0.732	0.73
86_L	92_I	0.731	0.73
260_E	281_E	0.730	0.73
79_H	142_H	0.729	0.73
251_K	292_K	0.728	0.73
9_T	156_P	0.726	0.72
258_S	301_Q	0.726	0.72
128_V	137_F	0.726	0.72
35_L	86_L	0.725	0.72
403_A	408_I	0.725	0.72
474_D	481_S	0.725	0.72
326_T	354_E	0.725	0.72
346_N	392_E	0.724	0.72
78_D	142_H	0.723	0.72
453_I	549_L	0.722	0.72
17_L	25_Y	0.719	0.72
86_L	90_V	0.716	0.71
68_K	95_Y	0.716	0.71
550_P	553_M	0.715	0.71
321_I	351_A	0.713	0.71
451_G	454_V	0.713	0.71
185_G	189_V	0.713	0.71
108_L	117_T	0.711	0.71
190_L	385_F	0.710	0.71
488_S	492_V	0.705	0.70
16_G	21_G	0.704	0.70
67_I	70_L	0.703	0.70
76_H	366_S	0.703	0.70
285_I	295_I	0.702	0.70
467_V	504_A	0.702	0.70
240_Q	244_A	0.701	0.70
502_N	514_K	0.700	0.70
375_K	406_C	0.700	0.70
284_E	288_M	0.699	0.70
57_Y	61_V	0.698	0.69
69_G	95_Y	0.695	0.69
246_V	252_V	0.695	0.69
113_L	116_Q	0.693	0.69
243_E	246_V	0.693	0.69
396_Q	399_H	0.691	0.69
87_L	90_V	0.688	0.68
534_L	538_L	0.688	0.68
105_R	109_E	0.688	0.68
156_P	427_D	0.687	0.68
349_Y	355_V	0.687	0.68
15_G	21_G	0.686	0.68
443_D	454_V	0.686	0.68
539_Y	542_T	0.685	0.68
513_Q	517_E	0.684	0.68
197_T	336_G	0.683	0.68
245_A	252_V	0.682	0.68
527_K	551_I	0.682	0.68
527_K	531_T	0.680	0.67
197_T	368_H	0.680	0.67
225_R	293_V	0.679	0.67
399_H	408_I	0.677	0.67
387_M	424_L	0.675	0.67
364_H	367_G	0.673	0.67
532_D	547_M	0.671	0.66
103_L	262_A	0.671	0.66
503_D	506_E	0.671	0.66
444_G	461_L	0.671	0.66
140_T	377_M	0.670	0.66
483_G	509_S	0.669	0.66
38_A	70_L	0.668	0.66
50_I	529_E	0.668	0.66
298_T	306_A	0.667	0.66
346_N	458_R	0.667	0.66
514_K	525_E	0.665	0.66
301_Q	334_I	0.664	0.66
345_I	349_Y	0.664	0.66
491_F	544_R	0.663	0.66
453_I	457_D	0.662	0.65
79_H	231_F	0.661	0.65
42_F	78_D	0.661	0.65
142_H	237_R	0.660	0.65
204_F	370_G	0.660	0.65
372_E	376_L	0.660	0.65
538_L	541_K	0.659	0.65
194_S	374_Q	0.659	0.65
54_I	447_I	0.659	0.65
229_A	360_L	0.658	0.65
200_E	398_M	0.657	0.65
504_A	508_I	0.657	0.65
270_G	273_N	0.656	0.65
91_N	118_K	0.656	0.65
91_N	117_T	0.655	0.65
159_I	191_C	0.654	0.64
225_R	290_A	0.653	0.64
208_E	367_G	0.653	0.64
337_N	390_H	0.653	0.64
290_A	293_V	0.653	0.64
532_D	536_P	0.652	0.64
424_L	429_A	0.651	0.64
215_I	244_A	0.651	0.64
78_D	390_H	0.651	0.64
184_I	381_I	0.651	0.64
536_P	540_E	0.650	0.64
448_G	455_L	0.650	0.64
185_G	380_L	0.650	0.64
204_F	373_E	0.648	0.64
158_N	184_I	0.647	0.64
196_S	392_E	0.646	0.64
214_S	361_N	0.645	0.63
422_L	429_A	0.643	0.63
252_V	277_N	0.643	0.63
387_M	416_M	0.642	0.63
78_D	366_S	0.642	0.63
526_I	530_I	0.642	0.63
57_Y	60_L	0.642	0.63
234_N	367_G	0.639	0.63
218_I	363_I	0.639	0.63
482_A	509_S	0.639	0.63
502_N	507_L	0.638	0.63
485_D	498_G	0.637	0.62
125_D	180_K	0.637	0.62
162_T	197_T	0.637	0.62
334_I	390_H	0.636	0.62
489_R	549_L	0.636	0.62
385_F	429_A	0.634	0.62
501_I	505_Q	0.633	0.62
285_I	319_I	0.633	0.62
531_T	550_P	0.632	0.62
454_V	457_D	0.632	0.62
301_Q	336_G	0.632	0.62
59_Y	63_N	0.631	0.62
495_R	498_G	0.631	0.62
357_H	360_L	0.630	0.62
100_A	122_I	0.627	0.61
246_V	277_N	0.625	0.61
301_Q	390_H	0.624	0.61
181_M	184_I	0.624	0.61
518_R	536_P	0.624	0.61
214_S	218_I	0.623	0.61
122_I	135_V	0.623	0.61
544_R	550_P	0.623	0.61
375_K	402_L	0.621	0.60
33_I	63_N	0.621	0.60
94_V	104_L	0.620	0.60
482_A	553_M	0.619	0.60
232_A	390_H	0.619	0.60
197_T	303_E	0.616	0.60
517_E	520_T	0.615	0.60
29_F	133_T	0.615	0.60
83_I	111_H	0.615	0.60
295_I	307_A	0.614	0.60
15_G	23_N	0.614	0.60
208_E	301_Q	0.613	0.59
60_L	63_N	0.612	0.59
530_I	534_L	0.611	0.59
224_G	324_G	0.610	0.59
100_A	338_T	0.608	0.59
221_K	354_E	0.607	0.59
166_K	171_P	0.607	0.59
19_E	438_G	0.607	0.59
179_T	186_K	0.605	0.58
523_W	527_K	0.605	0.58
330_S	364_H	0.605	0.58
147_S	369_G	0.605	0.58
527_K	549_L	0.605	0.58
17_L	389_I	0.604	0.58
227_I	311_I	0.604	0.58
486_L	505_Q	0.603	0.58
72_I	82_G	0.602	0.58
12_F	33_I	0.602	0.58
488_S	491_F	0.601	0.58
38_A	82_G	0.600	0.58
25_Y	193_L	0.600	0.58
475_M	525_E	0.598	0.58
474_D	482_A	0.597	0.57
123_G	128_V	0.597	0.57
481_S	484_P	0.597	0.57
393_Y	397_K	0.597	0.57
458_R	462_S	0.596	0.57
25_Y	378_L	0.596	0.57
512_L	518_R	0.596	0.57
231_F	301_Q	0.596	0.57
504_A	539_Y	0.595	0.57
34_V	152_V	0.594	0.57
470_V	485_D	0.593	0.57
414_F	431_V	0.593	0.57
217_D	220_R	0.593	0.57
256_G	348_L	0.593	0.57
27_V	34_V	0.593	0.57
192_L	378_L	0.592	0.57
470_V	479_K	0.592	0.57
524_S	527_K	0.591	0.57
14_L	435_I	0.590	0.57
230_T	296_L	0.589	0.56
515_V	529_E	0.589	0.56
508_I	533_T	0.588	0.56
369_G	373_E	0.588	0.56
8_Q	26_A	0.588	0.56
468_I	551_I	0.588	0.56
277_N	284_E	0.587	0.56
87_L	92_I	0.587	0.56
297_C	311_I	0.585	0.56
180_K	530_I	0.585	0.56
234_N	240_Q	0.585	0.56
329_F	344_T	0.584	0.56
15_G	18_G	0.584	0.56
527_K	542_T	0.584	0.56
488_S	501_I	0.583	0.56
376_L	379_R	0.583	0.56
302_G	367_G	0.582	0.56
42_F	77_E	0.582	0.56
197_T	301_Q	0.582	0.56
483_G	495_R	0.582	0.56
147_S	358_G	0.582	0.56
218_I	326_T	0.580	0.55
84_P	111_H	0.580	0.55
61_V	90_V	0.579	0.55
419_G	458_R	0.579	0.55
228_F	294_T	0.579	0.55
295_I	319_I	0.579	0.55
140_T	362_D	0.578	0.55
487_I	491_F	0.576	0.55
513_Q	516_M	0.576	0.55
161_H	389_I	0.576	0.55
522_Q	525_E	0.575	0.55
279_F	282_H	0.574	0.55
21_G	390_H	0.574	0.55
386_F	413_C	0.574	0.55
464_E	538_L	0.572	0.54
538_L	542_T	0.571	0.54
214_S	217_D	0.571	0.54
485_D	505_Q	0.570	0.54
37_D	142_H	0.570	0.54
72_I	405_D	0.570	0.54
54_I	442_I	0.568	0.54
145_P	262_A	0.567	0.54
469_V	486_L	0.566	0.54
38_A	86_L	0.566	0.54
109_E	314_G	0.566	0.54
58_T	63_N	0.565	0.53
539_Y	552_I	0.564	0.53
223_D	326_T	0.564	0.53
301_Q	364_H	0.564	0.53
505_Q	533_T	0.564	0.53
255_F	282_H	0.564	0.53
251_K	280_I	0.563	0.53
229_A	363_I	0.563	0.53
83_I	104_L	0.563	0.53
178_L	344_T	0.563	0.53
470_V	550_P	0.563	0.53
520_T	525_E	0.562	0.53
320_S	536_P	0.561	0.53
124_E	139_R	0.560	0.53
42_F	197_T	0.560	0.53
279_F	284_E	0.560	0.53
512_L	520_T	0.559	0.53
424_L	428_E	0.559	0.53
481_S	510_N	0.559	0.53
20_I	42_F	0.559	0.53
76_H	163_G	0.559	0.53
168_D	171_P	0.558	0.53
507_L	510_N	0.558	0.53
253_A	282_H	0.558	0.53
300_S	390_H	0.558	0.53
55_P	82_G	0.557	0.52
499_D	502_N	0.557	0.52
505_Q	509_S	0.557	0.52
527_K	552_I	0.556	0.52
137_F	148_Y	0.556	0.52
535_A	548_I	0.555	0.52
223_D	226_I	0.555	0.52
471_V	481_S	0.554	0.52
194_S	381_I	0.554	0.52
381_I	386_F	0.553	0.52
169_F	204_F	0.553	0.52
451_G	491_F	0.552	0.52
199_S	413_C	0.552	0.52
18_G	417_D	0.551	0.52
208_E	237_R	0.551	0.52
461_L	464_E	0.551	0.52
384_K	426_G	0.550	0.51
141_T	176_A	0.550	0.51
453_I	553_M	0.550	0.51
476_D	516_M	0.550	0.51
76_H	197_T	0.549	0.51
484_P	550_P	0.549	0.51
188_G	250_R	0.548	0.51
40_I	53_V	0.548	0.51
10_A	66_K	0.547	0.51
97_G	122_I	0.546	0.51
208_E	364_H	0.546	0.51
74_H	366_S	0.546	0.51
151_V	160_V	0.546	0.51
42_F	258_S	0.545	0.51
97_G	191_C	0.543	0.51
448_G	451_G	0.543	0.51
297_C	306_A	0.541	0.50
64_E	90_V	0.541	0.50
385_F	428_E	0.541	0.50
108_L	119_L	0.541	0.50
397_K	401_K	0.540	0.50
470_V	487_I	0.540	0.50
420_E	434_K	0.539	0.50
496_E	502_N	0.538	0.50
371_Q	405_D	0.538	0.50
480_I	526_I	0.538	0.50
453_I	523_W	0.538	0.50
542_T	545_R	0.537	0.50
441_Y	455_L	0.536	0.50
28_Q	31_D	0.536	0.50
335_P	367_G	0.535	0.50
350_R	393_Y	0.535	0.50
321_I	348_L	0.534	0.49
536_P	553_M	0.533	0.49
220_R	401_K	0.533	0.49
474_D	479_K	0.531	0.49
95_Y	120_N	0.530	0.49
102_G	265_I	0.530	0.49
208_E	232_A	0.529	0.49
32_E	130_F	0.529	0.49
51_D	448_G	0.528	0.49
273_N	277_N	0.527	0.49
163_G	368_H	0.527	0.49
486_L	534_L	0.527	0.49
195_D	368_H	0.526	0.48
168_D	208_E	0.526	0.48
299_G	303_E	0.526	0.48
185_G	188_G	0.525	0.48
220_R	248_N	0.522	0.48
507_L	541_K	0.522	0.48
483_G	498_G	0.522	0.48
198_N	390_H	0.521	0.48
233_S	301_Q	0.520	0.48
296_L	437_S	0.520	0.48
443_D	457_D	0.519	0.47
166_K	302_G	0.519	0.47
346_N	354_E	0.519	0.47
231_F	334_I	0.519	0.47
74_H	237_R	0.519	0.47
378_L	395_M	0.518	0.47
479_K	513_Q	0.518	0.47
78_D	163_G	0.518	0.47
481_S	506_E	0.516	0.47
512_L	516_M	0.516	0.47
105_R	268_T	0.516	0.47
97_G	338_T	0.515	0.47
87_L	91_N	0.515	0.47
79_H	337_N	0.515	0.47
532_D	542_T	0.513	0.47
137_F	392_E	0.513	0.47
144_I	306_A	0.513	0.47
44_E	534_L	0.512	0.47
125_D	149_G	0.511	0.46
77_E	258_S	0.511	0.46
540_E	545_R	0.511	0.46
259_M	296_L	0.511	0.46
94_V	180_K	0.511	0.46
335_P	364_H	0.510	0.46
101_I	105_R	0.510	0.46
472_S	481_S	0.510	0.46
56_D	60_L	0.510	0.46
539_Y	545_R	0.510	0.46
461_L	470_V	0.509	0.46
523_W	549_L	0.509	0.46
401_K	405_D	0.508	0.46
53_V	504_A	0.508	0.46
226_I	326_T	0.508	0.46
282_H	286_N	0.507	0.46
226_I	294_T	0.507	0.46
93_P	120_N	0.507	0.46
325_D	465_G	0.506	0.46
122_I	125_D	0.506	0.46
176_A	369_G	0.506	0.46
140_T	160_V	0.505	0.46
495_R	501_I	0.505	0.46
480_I	484_P	0.505	0.46
258_S	364_H	0.505	0.46
527_K	547_M	0.505	0.46
95_Y	547_M	0.504	0.46
253_A	319_I	0.504	0.46
303_E	390_H	0.504	0.46
372_E	442_I	0.503	0.45
500_L	507_L	0.502	0.45
300_S	337_N	0.501	0.45
469_V	504_A	0.501	0.45
524_S	553_M	0.500	0.45

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zq4A	3	0.991	100	0.212	Contact Map
3bk2A	2	0.9748	100	0.235	Contact Map
2az4A	1	0.6937	100	0.506	Contact Map
3iekA	3	0.6919	100	0.542	Contact Map
2ycbA	2	0.7261	100	0.553	Contact Map
2i7tA	1	0.6649	100	0.556	Contact Map
2xr1A	2	0.7189	100	0.559	Contact Map
3af5A	1	0.7279	100	0.564	Contact Map
2i7xA	1	0.6955	100	0.591	Contact Map
4b87A	1	0.5748	100	0.631	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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