GREMLIN Database
RNJ1 - Ribonuclease J1
UniProt: Q45493 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 555 (542)
Sequences: 3042 (1842)
Seq/√Len: 79.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
32_E68_K5.9471.00
72_I104_L5.0281.00
70_L83_I4.6551.00
219_F226_I4.4581.00
97_G148_Y4.1321.00
153_K187_E3.8751.00
61_V89_Q3.8051.00
290_A322_N3.5281.00
27_V36_I3.5231.00
288_M293_V3.4571.00
191_C387_M3.3621.00
151_V158_N3.2711.00
9_T159_I3.2231.00
216_H247_Q3.0881.00
280_I288_M3.0201.00
245_A294_T2.9071.00
321_I353_A2.8341.00
138_F149_G2.8281.00
127_I134_A2.7871.00
253_A285_I2.7761.00
416_M422_L2.7271.00
96_G104_L2.7241.00
153_K158_N2.6971.00
400_V404_T2.6461.00
35_L67_I2.5731.00
129_K134_A2.5631.00
414_F422_L2.5481.00
36_I152_V2.5221.00
32_E132_K2.5011.00
63_N66_K2.5001.00
387_M422_L2.4901.00
60_L67_I2.4541.00
123_G126_D2.4211.00
386_F399_H2.3511.00
228_F241_V2.3421.00
36_I73_T2.3361.00
372_E375_K2.3351.00
72_I100_A2.3311.00
242_I252_V2.3161.00
192_L381_I2.3101.00
205_T370_G2.2871.00
10_A28_Q2.2811.00
33_I60_L2.2761.00
57_Y86_L2.2671.00
404_T410_E2.2671.00
31_D66_K2.2641.00
183_E186_K2.2551.00
254_V263_I2.2521.00
71_F150_I2.2421.00
194_S378_L2.2411.00
35_L60_L2.2241.00
162_T377_M2.2141.00
33_I67_I2.2091.00
374_Q402_L2.2081.00
11_V191_C2.1911.00
96_G101_I2.1861.00
186_K382_K2.1741.00
134_A153_K2.1621.00
312_A347_Q2.1391.00
72_I96_G2.1221.00
281_E284_E2.1001.00
70_L92_I2.0911.00
400_V413_C2.0841.00
246_V275_P2.0741.00
219_F294_T2.0421.00
151_V184_I2.0321.00
160_V381_I2.0291.00
36_I150_I1.9641.00
101_I119_L1.9511.00
136_S180_K1.9331.00
274_C279_F1.9241.00
249_G292_K1.9191.00
386_F403_A1.8661.00
137_F150_I1.8501.00
88_R111_H1.8291.00
216_H248_N1.8261.00
401_K404_T1.8021.00
224_G326_T1.7851.00
350_R417_D1.7791.00
421_V435_I1.7701.00
32_E66_K1.7661.00
34_V71_F1.7591.00
504_A534_L1.7381.00
480_I483_G1.7361.00
218_I328_V1.7311.00
12_F421_V1.7031.00
29_F155_P1.6951.00
24_T35_L1.6941.00
241_V294_T1.6901.00
122_I137_F1.6881.00
181_M381_I1.6821.00
167_F176_A1.6741.00
386_F408_I1.6701.00
165_F194_S1.6691.00
140_T147_S1.6511.00
190_L384_K1.6431.00
378_L408_I1.6391.00
194_S399_H1.6291.00
289_P292_K1.6261.00
83_I94_V1.6241.00
467_V538_L1.6191.00
34_V133_T1.6181.00
284_E287_R1.6141.00
71_F135_V1.5951.00
400_V415_I1.5951.00
194_S386_F1.5901.00
160_V192_L1.5861.00
503_D541_K1.5781.00
61_V64_E1.5761.00
425_K428_E1.5731.00
180_K183_E1.5600.99
511_H533_T1.5590.99
421_V433_G1.5390.99
98_K121_I1.5360.99
421_V432_A1.5310.99
8_Q423_A1.5260.99
202_P371_Q1.5190.99
71_F130_F1.5160.99
199_S374_Q1.5160.99
371_Q402_L1.5080.99
28_Q66_K1.4880.99
199_S398_M1.4860.99
135_V150_I1.4850.99
217_D221_K1.4810.99
27_V152_V1.4660.99
285_I293_V1.4650.99
469_V534_L1.4640.99
17_L416_M1.4610.99
70_L86_L1.4590.99
106_N265_I1.4550.99
267_Q276_K1.4530.99
189_V381_I1.4450.99
26_A33_I1.4320.99
34_V135_V1.4260.99
36_I161_H1.4140.99
264_E268_T1.4140.99
178_L182_A1.4130.99
222_V326_T1.4110.99
244_A248_N1.4030.99
69_G130_F1.4020.99
507_L511_H1.3950.99
311_I319_I1.3910.99
34_V68_K1.3790.99
378_L386_F1.3760.99
169_F379_R1.3710.99
472_S482_A1.3700.99
285_I288_M1.3690.99
404_T413_C1.3680.99
509_S513_Q1.3420.98
160_V184_I1.3350.98
136_S153_K1.3330.98
14_L26_A1.3260.98
246_V278_T1.3230.98
243_E273_N1.3170.98
72_I83_I1.3120.98
212_G240_Q1.3070.98
87_L108_L1.3030.98
379_R406_C1.3030.98
530_I533_T1.3020.98
235_I262_A1.3020.98
57_Y90_V1.3000.98
102_G269_L1.2930.98
252_V278_T1.2930.98
101_I121_I1.2870.98
223_D291_N1.2720.98
58_T61_V1.2690.98
154_T157_G1.2690.98
97_G100_A1.2620.98
122_I148_Y1.2560.98
138_F160_V1.2530.98
306_A309_S1.2510.98
196_S399_H1.2430.97
398_M401_K1.2430.97
472_S553_M1.2420.97
511_H529_E1.2400.97
15_G19_E1.2370.97
205_T365_T1.2370.97
283_N318_Q1.2360.97
457_D489_R1.2340.97
8_Q425_K1.2290.97
176_A181_M1.2260.97
76_H368_H1.2220.97
128_V135_V1.2190.97
502_N505_Q1.2170.97
409_P412_N1.2160.97
288_M292_K1.2140.97
79_H390_H1.2090.97
27_V159_I1.2020.97
280_I284_E1.2020.97
83_I92_I1.1980.97
74_H142_H1.1910.97
138_F180_K1.1910.97
26_A60_L1.1900.97
47_L53_V1.1860.97
378_L399_H1.1810.96
140_T181_M1.1780.96
28_Q59_Y1.1760.96
416_M431_V1.1670.96
231_F390_H1.1640.96
500_L538_L1.1630.96
274_C277_N1.1630.96
414_F429_A1.1600.96
280_I293_V1.1600.96
210_R213_E1.1590.96
239_Q243_E1.1570.96
75_G103_L1.1550.96
504_A538_L1.1530.96
158_N187_E1.1510.96
204_F372_E1.1500.96
332_S341_V1.1490.96
11_V193_L1.1470.96
197_T390_H1.1420.96
199_S402_L1.1400.96
17_L418_N1.1360.96
80_I103_L1.1360.96
124_E148_Y1.1320.96
9_T29_F1.1310.96
231_F336_G1.1250.95
179_T182_A1.1240.95
34_V130_F1.1230.95
183_E187_E1.1220.95
218_I356_I1.1190.95
122_I128_V1.1070.95
257_R310_R1.0800.94
470_V551_I1.0790.94
139_R146_D1.0760.94
27_V161_H1.0730.94
79_H164_D1.0710.94
267_Q277_N1.0700.94
508_I530_I1.0670.94
321_I327_V1.0650.94
500_L542_T1.0640.94
106_N261_S1.0630.94
33_I59_Y1.0630.94
29_F132_K1.0620.94
73_T161_H1.0620.94
435_I438_G1.0610.94
191_C424_L1.0570.94
272_I275_P1.0560.94
76_H142_H1.0520.93
71_F128_V1.0480.93
263_I296_L1.0460.93
130_F133_T1.0410.93
254_V279_F1.0320.93
345_I355_V1.0280.93
471_V512_L1.0270.93
377_M381_I1.0260.93
333_P341_V1.0230.92
486_L504_A1.0210.92
253_A280_I1.0210.92
78_D368_H1.0210.92
354_E401_K1.0170.92
501_I504_A1.0170.92
135_V152_V1.0140.92
420_E431_V1.0090.92
147_S163_G1.0090.92
74_H79_H1.0090.92
212_G244_A1.0050.92
458_R465_G1.0040.92
34_V69_G1.0030.92
193_L389_I1.0020.92
515_V520_T0.9990.91
516_M520_T0.9960.91
26_A35_L0.9950.91
140_T176_A0.9940.91
385_F424_L0.9900.91
478_F516_M0.9900.91
58_T436_P0.9830.91
127_I136_S0.9790.91
396_Q415_I0.9790.91
506_E509_S0.9790.91
25_Y389_I0.9780.91
306_A329_F0.9730.90
165_F374_Q0.9720.90
100_A239_Q0.9710.90
30_Q132_K0.9690.90
216_H220_R0.9670.90
40_I52_Y0.9630.90
10_A421_V0.9560.90
222_V226_I0.9530.89
124_E177_N0.9520.89
13_A25_Y0.9500.89
197_T231_F0.9480.89
58_T62_K0.9460.89
534_L548_I0.9440.89
507_L530_I0.9420.89
149_G160_V0.9390.89
528_N532_D0.9360.89
446_G449_D0.9350.89
11_V387_M0.9290.88
136_S151_V0.9260.88
167_F377_M0.9240.88
167_F178_L0.9230.88
28_Q33_I0.9210.88
237_R367_G0.9210.88
238_L263_I0.9190.88
485_D495_R0.9140.87
182_A380_L0.9140.87
528_N531_T0.9080.87
491_F542_T0.9080.87
515_V526_I0.9080.87
70_L94_V0.9060.87
508_I511_H0.9050.87
32_E131_R0.9030.87
72_I101_I0.9030.87
11_V25_Y0.8950.86
19_E418_N0.8930.86
334_I337_N0.8920.86
215_I219_F0.8900.86
112_G117_T0.8890.86
102_G268_T0.8890.86
301_Q337_N0.8870.86
153_K184_I0.8860.86
255_F311_I0.8830.86
78_D197_T0.8810.85
446_G451_G0.8800.85
535_A545_R0.8790.85
20_I197_T0.8790.85
12_F26_A0.8770.85
75_G144_I0.8760.85
255_F319_I0.8750.85
507_L537_F0.8730.85
492_V500_L0.8730.85
74_H368_H0.8670.84
12_F59_Y0.8670.84
216_H244_A0.8670.84
408_I412_N0.8660.84
227_I297_C0.8640.84
64_E67_I0.8630.84
74_H78_D0.8630.84
87_L94_V0.8610.84
140_T149_G0.8610.84
525_E529_E0.8600.84
157_G190_L0.8590.84
385_F414_F0.8540.84
25_Y36_I0.8520.83
280_I285_I0.8470.83
178_L181_M0.8450.83
508_I512_L0.8430.83
309_S313_N0.8410.83
203_E372_E0.8400.83
492_V542_T0.8390.82
138_F184_I0.8380.82
105_R121_I0.8370.82
200_E394_R0.8360.82
79_H197_T0.8350.82
511_H530_I0.8310.82
182_A185_G0.8300.82
444_G448_G0.8300.82
417_D420_E0.8290.82
142_H368_H0.8280.82
22_K333_P0.8270.82
11_V27_V0.8260.82
470_V553_M0.8260.82
309_S344_T0.8250.81
38_A57_Y0.8190.81
221_K469_V0.8170.81
529_E533_T0.8150.81
314_G320_S0.8140.81
24_T57_Y0.8140.81
27_V133_T0.8130.80
160_V189_V0.8130.80
64_E91_N0.8120.80
139_R174_E0.8120.80
480_I516_M0.8120.80
9_T155_P0.8110.80
244_A247_Q0.8110.80
22_K332_S0.8110.80
417_D434_K0.8090.80
453_I456_R0.8080.80
507_L533_T0.8080.80
471_V530_I0.8070.80
159_I193_L0.8070.80
503_D537_F0.8030.80
12_F435_I0.8010.79
32_E69_G0.8000.79
226_I328_V0.7950.79
33_I66_K0.7940.79
71_F131_R0.7940.79
399_H403_A0.7920.79
280_I287_R0.7890.78
423_A432_A0.7850.78
19_E22_K0.7840.78
468_I485_D0.7810.78
204_F376_L0.7800.78
273_N276_K0.7790.78
113_L117_T0.7780.77
96_G119_L0.7770.77
10_A423_A0.7770.77
423_A430_S0.7770.77
495_R532_D0.7760.77
313_N347_Q0.7760.77
192_L386_F0.7760.77
532_D539_Y0.7750.77
347_Q350_R0.7750.77
138_F181_M0.7750.77
384_K412_N0.7730.77
98_K123_G0.7710.77
537_F541_K0.7690.77
178_L377_M0.7690.77
163_G197_T0.7680.77
203_E370_G0.7680.77
506_E510_N0.7670.76
100_A148_Y0.7670.76
98_K271_Y0.7670.76
298_T303_E0.7630.76
194_S408_I0.7620.76
106_N109_E0.7610.76
314_G351_A0.7600.76
162_T192_L0.7580.76
97_G146_D0.7570.76
188_G384_K0.7560.75
219_F248_N0.7540.75
68_K132_K0.7520.75
449_D453_I0.7510.75
311_I316_H0.7500.75
9_T27_V0.7490.75
397_K400_V0.7480.75
492_V495_R0.7470.75
242_I246_V0.7470.75
129_K132_K0.7470.75
539_Y543_K0.7440.74
24_T38_A0.7420.74
274_C278_T0.7370.74
194_S377_M0.7370.74
77_E107_K0.7350.73
444_G447_I0.7350.73
201_N370_G0.7340.73
108_L113_L0.7340.73
76_H79_H0.7340.73
213_E217_D0.7330.73
151_V190_L0.7320.73
164_D390_H0.7320.73
86_L92_I0.7310.73
260_E281_E0.7300.73
79_H142_H0.7290.73
251_K292_K0.7280.73
9_T156_P0.7260.72
258_S301_Q0.7260.72
128_V137_F0.7260.72
35_L86_L0.7250.72
403_A408_I0.7250.72
474_D481_S0.7250.72
326_T354_E0.7250.72
346_N392_E0.7240.72
78_D142_H0.7230.72
453_I549_L0.7220.72
17_L25_Y0.7190.72
86_L90_V0.7160.71
68_K95_Y0.7160.71
550_P553_M0.7150.71
321_I351_A0.7130.71
451_G454_V0.7130.71
185_G189_V0.7130.71
108_L117_T0.7110.71
190_L385_F0.7100.71
488_S492_V0.7050.70
16_G21_G0.7040.70
67_I70_L0.7030.70
76_H366_S0.7030.70
285_I295_I0.7020.70
467_V504_A0.7020.70
240_Q244_A0.7010.70
502_N514_K0.7000.70
375_K406_C0.7000.70
284_E288_M0.6990.70
57_Y61_V0.6980.69
69_G95_Y0.6950.69
246_V252_V0.6950.69
113_L116_Q0.6930.69
243_E246_V0.6930.69
396_Q399_H0.6910.69
87_L90_V0.6880.68
534_L538_L0.6880.68
105_R109_E0.6880.68
156_P427_D0.6870.68
349_Y355_V0.6870.68
15_G21_G0.6860.68
443_D454_V0.6860.68
539_Y542_T0.6850.68
513_Q517_E0.6840.68
197_T336_G0.6830.68
245_A252_V0.6820.68
527_K551_I0.6820.68
527_K531_T0.6800.67
197_T368_H0.6800.67
225_R293_V0.6790.67
399_H408_I0.6770.67
387_M424_L0.6750.67
364_H367_G0.6730.67
532_D547_M0.6710.66
103_L262_A0.6710.66
503_D506_E0.6710.66
444_G461_L0.6710.66
140_T377_M0.6700.66
483_G509_S0.6690.66
38_A70_L0.6680.66
50_I529_E0.6680.66
298_T306_A0.6670.66
346_N458_R0.6670.66
514_K525_E0.6650.66
301_Q334_I0.6640.66
345_I349_Y0.6640.66
491_F544_R0.6630.66
453_I457_D0.6620.65
79_H231_F0.6610.65
42_F78_D0.6610.65
142_H237_R0.6600.65
204_F370_G0.6600.65
372_E376_L0.6600.65
538_L541_K0.6590.65
194_S374_Q0.6590.65
54_I447_I0.6590.65
229_A360_L0.6580.65
200_E398_M0.6570.65
504_A508_I0.6570.65
270_G273_N0.6560.65
91_N118_K0.6560.65
91_N117_T0.6550.65
159_I191_C0.6540.64
225_R290_A0.6530.64
208_E367_G0.6530.64
337_N390_H0.6530.64
290_A293_V0.6530.64
532_D536_P0.6520.64
424_L429_A0.6510.64
215_I244_A0.6510.64
78_D390_H0.6510.64
184_I381_I0.6510.64
536_P540_E0.6500.64
448_G455_L0.6500.64
185_G380_L0.6500.64
204_F373_E0.6480.64
158_N184_I0.6470.64
196_S392_E0.6460.64
214_S361_N0.6450.63
422_L429_A0.6430.63
252_V277_N0.6430.63
387_M416_M0.6420.63
78_D366_S0.6420.63
526_I530_I0.6420.63
57_Y60_L0.6420.63
234_N367_G0.6390.63
218_I363_I0.6390.63
482_A509_S0.6390.63
502_N507_L0.6380.63
485_D498_G0.6370.62
125_D180_K0.6370.62
162_T197_T0.6370.62
334_I390_H0.6360.62
489_R549_L0.6360.62
385_F429_A0.6340.62
501_I505_Q0.6330.62
285_I319_I0.6330.62
531_T550_P0.6320.62
454_V457_D0.6320.62
301_Q336_G0.6320.62
59_Y63_N0.6310.62
495_R498_G0.6310.62
357_H360_L0.6300.62
100_A122_I0.6270.61
246_V277_N0.6250.61
301_Q390_H0.6240.61
181_M184_I0.6240.61
518_R536_P0.6240.61
214_S218_I0.6230.61
122_I135_V0.6230.61
544_R550_P0.6230.61
375_K402_L0.6210.60
33_I63_N0.6210.60
94_V104_L0.6200.60
482_A553_M0.6190.60
232_A390_H0.6190.60
197_T303_E0.6160.60
517_E520_T0.6150.60
29_F133_T0.6150.60
83_I111_H0.6150.60
295_I307_A0.6140.60
15_G23_N0.6140.60
208_E301_Q0.6130.59
60_L63_N0.6120.59
530_I534_L0.6110.59
224_G324_G0.6100.59
100_A338_T0.6080.59
221_K354_E0.6070.59
166_K171_P0.6070.59
19_E438_G0.6070.59
179_T186_K0.6050.58
523_W527_K0.6050.58
330_S364_H0.6050.58
147_S369_G0.6050.58
527_K549_L0.6050.58
17_L389_I0.6040.58
227_I311_I0.6040.58
486_L505_Q0.6030.58
72_I82_G0.6020.58
12_F33_I0.6020.58
488_S491_F0.6010.58
38_A82_G0.6000.58
25_Y193_L0.6000.58
475_M525_E0.5980.58
474_D482_A0.5970.57
123_G128_V0.5970.57
481_S484_P0.5970.57
393_Y397_K0.5970.57
458_R462_S0.5960.57
25_Y378_L0.5960.57
512_L518_R0.5960.57
231_F301_Q0.5960.57
504_A539_Y0.5950.57
34_V152_V0.5940.57
470_V485_D0.5930.57
414_F431_V0.5930.57
217_D220_R0.5930.57
256_G348_L0.5930.57
27_V34_V0.5930.57
192_L378_L0.5920.57
470_V479_K0.5920.57
524_S527_K0.5910.57
14_L435_I0.5900.57
230_T296_L0.5890.56
515_V529_E0.5890.56
508_I533_T0.5880.56
369_G373_E0.5880.56
8_Q26_A0.5880.56
468_I551_I0.5880.56
277_N284_E0.5870.56
87_L92_I0.5870.56
297_C311_I0.5850.56
180_K530_I0.5850.56
234_N240_Q0.5850.56
329_F344_T0.5840.56
15_G18_G0.5840.56
527_K542_T0.5840.56
488_S501_I0.5830.56
376_L379_R0.5830.56
302_G367_G0.5820.56
42_F77_E0.5820.56
197_T301_Q0.5820.56
483_G495_R0.5820.56
147_S358_G0.5820.56
218_I326_T0.5800.55
84_P111_H0.5800.55
61_V90_V0.5790.55
419_G458_R0.5790.55
228_F294_T0.5790.55
295_I319_I0.5790.55
140_T362_D0.5780.55
487_I491_F0.5760.55
513_Q516_M0.5760.55
161_H389_I0.5760.55
522_Q525_E0.5750.55
279_F282_H0.5740.55
21_G390_H0.5740.55
386_F413_C0.5740.55
464_E538_L0.5720.54
538_L542_T0.5710.54
214_S217_D0.5710.54
485_D505_Q0.5700.54
37_D142_H0.5700.54
72_I405_D0.5700.54
54_I442_I0.5680.54
145_P262_A0.5670.54
469_V486_L0.5660.54
38_A86_L0.5660.54
109_E314_G0.5660.54
58_T63_N0.5650.53
539_Y552_I0.5640.53
223_D326_T0.5640.53
301_Q364_H0.5640.53
505_Q533_T0.5640.53
255_F282_H0.5640.53
251_K280_I0.5630.53
229_A363_I0.5630.53
83_I104_L0.5630.53
178_L344_T0.5630.53
470_V550_P0.5630.53
520_T525_E0.5620.53
320_S536_P0.5610.53
124_E139_R0.5600.53
42_F197_T0.5600.53
279_F284_E0.5600.53
512_L520_T0.5590.53
424_L428_E0.5590.53
481_S510_N0.5590.53
20_I42_F0.5590.53
76_H163_G0.5590.53
168_D171_P0.5580.53
507_L510_N0.5580.53
253_A282_H0.5580.53
300_S390_H0.5580.53
55_P82_G0.5570.52
499_D502_N0.5570.52
505_Q509_S0.5570.52
527_K552_I0.5560.52
137_F148_Y0.5560.52
535_A548_I0.5550.52
223_D226_I0.5550.52
471_V481_S0.5540.52
194_S381_I0.5540.52
381_I386_F0.5530.52
169_F204_F0.5530.52
451_G491_F0.5520.52
199_S413_C0.5520.52
18_G417_D0.5510.52
208_E237_R0.5510.52
461_L464_E0.5510.52
384_K426_G0.5500.51
141_T176_A0.5500.51
453_I553_M0.5500.51
476_D516_M0.5500.51
76_H197_T0.5490.51
484_P550_P0.5490.51
188_G250_R0.5480.51
40_I53_V0.5480.51
10_A66_K0.5470.51
97_G122_I0.5460.51
208_E364_H0.5460.51
74_H366_S0.5460.51
151_V160_V0.5460.51
42_F258_S0.5450.51
97_G191_C0.5430.51
448_G451_G0.5430.51
297_C306_A0.5410.50
64_E90_V0.5410.50
385_F428_E0.5410.50
108_L119_L0.5410.50
397_K401_K0.5400.50
470_V487_I0.5400.50
420_E434_K0.5390.50
496_E502_N0.5380.50
371_Q405_D0.5380.50
480_I526_I0.5380.50
453_I523_W0.5380.50
542_T545_R0.5370.50
441_Y455_L0.5360.50
28_Q31_D0.5360.50
335_P367_G0.5350.50
350_R393_Y0.5350.50
321_I348_L0.5340.49
536_P553_M0.5330.49
220_R401_K0.5330.49
474_D479_K0.5310.49
95_Y120_N0.5300.49
102_G265_I0.5300.49
208_E232_A0.5290.49
32_E130_F0.5290.49
51_D448_G0.5280.49
273_N277_N0.5270.49
163_G368_H0.5270.49
486_L534_L0.5270.49
195_D368_H0.5260.48
168_D208_E0.5260.48
299_G303_E0.5260.48
185_G188_G0.5250.48
220_R248_N0.5220.48
507_L541_K0.5220.48
483_G498_G0.5220.48
198_N390_H0.5210.48
233_S301_Q0.5200.48
296_L437_S0.5200.48
443_D457_D0.5190.47
166_K302_G0.5190.47
346_N354_E0.5190.47
231_F334_I0.5190.47
74_H237_R0.5190.47
378_L395_M0.5180.47
479_K513_Q0.5180.47
78_D163_G0.5180.47
481_S506_E0.5160.47
512_L516_M0.5160.47
105_R268_T0.5160.47
97_G338_T0.5150.47
87_L91_N0.5150.47
79_H337_N0.5150.47
532_D542_T0.5130.47
137_F392_E0.5130.47
144_I306_A0.5130.47
44_E534_L0.5120.47
125_D149_G0.5110.46
77_E258_S0.5110.46
540_E545_R0.5110.46
259_M296_L0.5110.46
94_V180_K0.5110.46
335_P364_H0.5100.46
101_I105_R0.5100.46
472_S481_S0.5100.46
56_D60_L0.5100.46
539_Y545_R0.5100.46
461_L470_V0.5090.46
523_W549_L0.5090.46
401_K405_D0.5080.46
53_V504_A0.5080.46
226_I326_T0.5080.46
282_H286_N0.5070.46
226_I294_T0.5070.46
93_P120_N0.5070.46
325_D465_G0.5060.46
122_I125_D0.5060.46
176_A369_G0.5060.46
140_T160_V0.5050.46
495_R501_I0.5050.46
480_I484_P0.5050.46
258_S364_H0.5050.46
527_K547_M0.5050.46
95_Y547_M0.5040.46
253_A319_I0.5040.46
303_E390_H0.5040.46
372_E442_I0.5030.45
500_L507_L0.5020.45
300_S337_N0.5010.45
469_V504_A0.5010.45
524_S553_M0.5000.45
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3zq4A 3 0.991 100 0.212 Contact Map
3bk2A 2 0.9748 100 0.235 Contact Map
2az4A 1 0.6937 100 0.506 Contact Map
3iekA 3 0.6919 100 0.542 Contact Map
2ycbA 2 0.7261 100 0.553 Contact Map
2i7tA 1 0.6649 100 0.556 Contact Map
2xr1A 2 0.7189 100 0.559 Contact Map
3af5A 1 0.7279 100 0.564 Contact Map
2i7xA 1 0.6955 100 0.591 Contact Map
4b87A 1 0.5748 100 0.631 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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