GREMLIN Database
YNER - Uncharacterized protein YneR
UniProt: Q45063 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 95 (94)
Sequences: 323 (270)
Seq/√Len: 27.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
54_G71_L2.7341.00
14_K60_D2.5830.99
27_F81_V2.5470.99
7_E59_A2.3710.99
13_Y92_F2.2890.98
14_K64_F2.1940.98
38_Q92_F2.1350.98
34_C37_V2.1230.97
58_E61_G2.0870.97
83_Y88_D2.0470.97
29_V32_G2.0230.97
10_L13_Y1.9680.96
66_I74_F1.9420.96
28_F44_G1.9280.95
4_T80_L1.8830.95
8_D85_E1.8810.95
43_L94_Y1.8420.94
6_N80_L1.8010.93
56_T63_T1.7360.92
38_Q73_Y1.7060.91
8_D82_S1.6730.90
55_V74_F1.6700.90
84_S91_V1.6420.90
32_G73_Y1.5780.88
38_Q75_D1.4760.84
10_L60_D1.4410.82
13_Y90_P1.4250.82
67_E77_H1.4200.81
29_V38_Q1.4160.81
6_N82_S1.3770.79
68_E71_L1.3400.77
50_P67_E1.3400.77
52_E68_E1.3280.77
39_K92_F1.3280.77
77_H94_Y1.3010.75
74_F89_E1.1660.67
34_C39_K1.1420.65
11_N14_K1.1160.63
27_F79_L1.1000.62
29_V42_S1.0910.62
64_F67_E1.0560.59
20_E23_D1.0380.58
35_S43_L1.0150.56
11_N15_E1.0080.55
62_I65_F1.0030.55
36_N94_Y0.9870.54
69_S83_Y0.9700.53
17_L92_F0.9560.51
11_N65_F0.9510.51
36_N48_D0.9510.51
30_R73_Y0.9450.51
8_D84_S0.9310.50
65_F69_S0.9290.49
81_V92_F0.9280.49
53_A56_T0.9260.49
15_E88_D0.9130.48
4_T7_E0.8830.46
34_C38_Q0.8690.45
10_L64_F0.8670.45
5_I80_L0.8650.45
19_L22_G0.8570.44
45_V53_A0.8490.43
30_R71_L0.8420.43
34_C44_G0.8370.42
11_N28_F0.8350.42
26_R48_D0.8300.42
46_A57_A0.8270.42
47_K75_D0.8240.41
10_L62_I0.8220.41
3_M22_G0.8210.41
22_G44_G0.8150.41
42_S73_Y0.8140.41
31_Y70_D0.8070.40
7_E84_S0.7760.38
53_A67_E0.7750.38
3_M93_E0.7710.38
29_V73_Y0.7650.37
24_Q65_F0.7600.37
23_D47_K0.7510.36
34_C77_H0.7420.36
16_E62_I0.7360.35
35_S77_H0.7320.35
35_S78_D0.7320.35
20_E52_E0.7280.35
74_F78_D0.7280.35
57_A83_Y0.7220.34
17_L25_V0.7150.34
8_D86_D0.7130.34
13_Y83_Y0.7070.33
10_L14_K0.7050.33
52_E82_S0.7030.33
63_T75_D0.7020.33
64_F83_Y0.6800.31
33_G89_E0.6740.31
39_K60_D0.6550.30
31_Y73_Y0.6540.30
16_E19_L0.6470.29
31_Y37_V0.6450.29
31_Y42_S0.6430.29
55_V78_D0.6400.29
22_G81_V0.6300.28
7_E60_D0.6290.28
51_Q60_D0.6270.28
6_N41_F0.6190.27
18_D88_D0.6180.27
70_D74_F0.6160.27
86_D91_V0.6080.27
66_I94_Y0.6060.27
37_V77_H0.5920.26
40_G64_F0.5910.26
5_I58_E0.5910.26
21_S73_Y0.5890.26
3_M82_S0.5710.25
5_I64_F0.5680.24
24_Q50_P0.5660.24
24_Q63_T0.5650.24
38_Q77_H0.5600.24
60_D64_F0.5590.24
74_F90_P0.5590.24
36_N43_L0.5490.23
20_E36_N0.5480.23
62_I81_V0.5470.23
27_F92_F0.5470.23
58_E78_D0.5440.23
6_N91_V0.5390.23
30_R54_G0.5350.23
11_N20_E0.5340.23
36_N55_V0.5330.23
57_A68_E0.5300.22
32_G89_E0.5270.22
79_L92_F0.5250.22
42_S50_P0.5240.22
84_S87_A0.5240.22
29_V75_D0.5170.22
7_E11_N0.5170.22
26_R50_P0.5150.22
25_V29_V0.5120.21
30_R48_D0.5080.21
26_R40_G0.5020.21
52_E73_Y0.5010.21
56_T81_V0.5000.21
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1r94A 3 0.9368 99.6 0.589 Contact Map
2d2aA 2 0.9368 99.6 0.593 Contact Map
2k4zA 1 0.9368 99.6 0.602 Contact Map
1nwbA 1 0.9368 99.6 0.607 Contact Map
2apnA 1 0.9368 99.5 0.608 Contact Map
1x0gA 4 0.9263 99.5 0.627 Contact Map
2qgoA 1 0.8421 99.1 0.694 Contact Map
2p2eA 1 0.9263 99 0.696 Contact Map
2wtpA 2 0.6632 31.2 0.919 Contact Map
4xwxA 1 0.7158 17.7 0.928 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0054 seconds.