GREMLIN Database
COTY - Spore coat protein Y
UniProt: Q08311 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 162 (144)
Sequences: 133 (99)
Seq/√Len: 8.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
15_C92_C8.6671.00
53_F139_I3.4840.94
57_D60_G3.4180.94
18_V139_I3.0560.89
52_P142_L2.9490.87
87_E97_S2.9460.87
32_C36_C2.4980.77
51_I144_P2.4420.75
18_V60_G2.2810.69
18_V53_F2.2090.67
97_S126_D2.1510.65
89_L94_A2.1500.65
86_V94_A2.1480.65
22_L26_E2.1060.63
122_L142_L2.0140.59
26_E30_E1.7810.50
86_V89_L1.7760.50
39_N144_P1.7320.48
52_P122_L1.6580.45
65_T84_F1.5640.41
54_L62_L1.5370.40
14_V138_A1.5210.39
62_L66_F1.5130.39
98_I144_P1.5090.39
19_E90_C1.4890.38
51_I98_I1.4640.37
2_S5_K1.4460.36
49_D86_V1.4460.36
59_K62_L1.4460.36
6_T125_T1.4420.36
54_L142_L1.4190.35
90_C135_C1.3680.33
18_V57_D1.3640.33
51_I97_S1.3630.33
97_S144_P1.3610.33
52_P67_G1.3530.33
64_S82_I1.3440.32
32_C35_G1.3350.32
24_E97_S1.3280.32
87_E126_D1.3120.31
101_P143_S1.2980.31
97_S127_F1.2920.31
90_C137_C1.2870.30
17_A97_S1.2590.29
80_E139_I1.2500.29
94_A147_V1.2370.29
77_Q134_G1.1960.27
84_F96_L1.1710.26
20_K24_E1.1700.26
81_S98_I1.1690.26
60_G97_S1.1540.26
78_C119_F1.1380.25
28_V35_G1.1120.25
41_L87_E1.1040.24
46_A56_F1.1000.24
35_G98_I1.0870.24
56_F129_I1.0800.24
40_L122_L1.0740.23
20_K81_S1.0640.23
18_V92_C1.0570.23
17_A130_E1.0520.23
36_C93_C1.0490.23
14_V40_L1.0380.22
28_V40_L1.0360.22
35_G40_L1.0330.22
67_G98_I1.0140.22
85_R124_K0.9950.21
43_P65_T0.9920.21
122_L131_V0.9870.21
40_L52_P0.9860.21
16_D58_K0.9850.21
31_Q88_K0.9770.21
112_C139_I0.9730.21
41_L131_V0.9720.21
2_S8_G0.9690.20
12_N100_R0.9680.20
52_P98_I0.9570.20
39_N88_K0.9510.20
134_G139_I0.9430.20
54_L64_S0.9420.20
94_A136_F0.9380.20
51_I67_G0.9350.20
57_D127_F0.9260.19
59_K110_S0.9260.19
24_E65_T0.9150.19
25_Q50_T0.9040.19
65_T128_C0.9020.19
51_I87_E0.8830.18
12_N91_D0.8740.18
19_E104_V0.8720.18
65_T98_I0.8700.18
49_D95_T0.8660.18
42_N129_I0.8650.18
43_P116_D0.8630.18
56_F142_L0.8570.18
111_V145_E0.8540.17
19_E23_A0.8520.17
30_E134_G0.8460.17
39_N49_D0.8310.17
96_L131_V0.8280.17
53_F78_C0.8260.17
67_G144_P0.8260.17
13_C141_C0.8230.17
81_S87_E0.8130.17
48_K67_G0.8050.16
12_N19_E0.8030.16
11_E107_D0.7970.16
101_P140_Q0.7970.16
84_F131_V0.7860.16
79_F105_K0.7820.16
17_A145_E0.7820.16
60_G87_E0.7780.16
67_G97_S0.7740.16
28_V78_C0.7720.16
27_A139_I0.7720.16
126_D140_Q0.7690.16
97_S140_Q0.7680.16
5_K74_D0.7630.15
53_F60_G0.7580.15
61_G66_F0.7560.15
52_P99_L0.7560.15
18_V54_L0.7550.15
20_K147_V0.7520.15
14_V122_L0.7380.15
98_I142_L0.7350.15
17_A138_A0.7300.15
57_D97_S0.7290.15
103_D106_G0.7270.15
28_V51_I0.7260.15
2_S113_H0.7260.15
25_Q63_F0.7250.15
23_A121_G0.7160.14
50_T63_F0.7130.14
83_F112_C0.7110.14
2_S66_F0.7110.14
15_C86_V0.7100.14
79_F124_K0.7070.14
7_H15_C0.6880.14
24_E143_S0.6810.14
64_S110_S0.6770.14
21_I129_I0.6730.14
65_T147_V0.6680.13
60_G127_F0.6640.13
13_C93_C0.6560.13
48_K143_S0.6530.13
81_S118_D0.6520.13
24_E52_P0.6510.13
16_D124_K0.6470.13
82_I114_P0.6470.13
100_R145_E0.6450.13
93_C141_C0.6290.13
41_L50_T0.6280.13
24_E98_I0.6270.13
16_D39_N0.6260.13
54_L122_L0.6230.13
111_V140_Q0.6220.13
56_F125_T0.6200.13
13_C128_C0.6170.13
78_C112_C0.6160.12
58_K77_Q0.6130.12
19_E37_Y0.6120.12
114_P145_E0.6110.12
24_E144_P0.6110.12
82_I101_P0.6070.12
102_V106_G0.6060.12
87_E124_K0.6010.12
58_K128_C0.5950.12
49_D112_C0.5940.12
25_Q85_R0.5910.12
111_V114_P0.5910.12
24_E57_D0.5900.12
60_G147_V0.5890.12
9_R105_K0.5870.12
83_F121_G0.5840.12
21_I25_Q0.5820.12
22_L89_L0.5800.12
7_H11_E0.5760.12
24_E39_N0.5750.12
61_G102_V0.5700.12
20_K39_N0.5650.12
24_E126_D0.5640.12
139_I146_L0.5630.12
49_D94_A0.5610.12
28_V98_I0.5570.11
65_T81_S0.5510.11
12_N134_G0.5500.11
63_F85_R0.5490.11
14_V140_Q0.5460.11
83_F139_I0.5440.11
21_I50_T0.5430.11
55_V136_F0.5420.11
15_C18_V0.5400.11
5_K12_N0.5370.11
39_N51_I0.5370.11
59_K92_C0.5360.11
21_I139_I0.5360.11
97_S143_S0.5350.11
70_G111_V0.5340.11
93_C132_D0.5340.11
40_L142_L0.5330.11
67_G127_F0.5240.11
120_F143_S0.5240.11
69_V91_D0.5240.11
86_V95_T0.5230.11
16_D77_Q0.5210.11
22_L53_F0.5200.11
67_G126_D0.5190.11
31_Q118_D0.5170.11
125_T139_I0.5150.11
50_T85_R0.5150.11
59_K120_F0.5120.11
49_D61_G0.5080.11
93_C137_C0.5080.11
17_A108_T0.5030.11
60_G98_I0.5010.11
94_A133_L0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1rjuV 1 0.2222 2.7 0.97 Contact Map
2l9zA 1 0.2407 2.2 0.971 Contact Map
4ux8A 1 0.1481 2 0.971 Contact Map
1fu9A 1 0.216 1.6 0.973 Contact Map
2v2fA 1 0.0926 1.6 0.973 Contact Map
2h85A 4 0.3765 1.4 0.974 Contact Map
2jysA 1 0.2778 1.3 0.974 Contact Map
4dvkA 1 0.4568 1.2 0.975 Contact Map
2xeuA 2 0.2407 1 0.976 Contact Map
1g92A 1 0.0864 1 0.977 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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