GREMLIN Database
PBPB - Penicillin-binding protein 2B
UniProt: Q07868 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 716 (561)
Sequences: 9990 (7197)
Seq/√Len: 303.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
270_A575_T3.4581.00
458_D463_K3.2651.00
272_V549_I3.2051.00
279_K454_D3.1921.00
446_K475_T3.1411.00
199_E209_R3.1381.00
537_M550_Y3.0991.00
279_K451_Y3.0881.00
486_R539_M3.0601.00
208_E217_S2.9571.00
490_G509_D2.9331.00
69_L239_N2.8721.00
512_G536_F2.7821.00
325_E384_R2.7531.00
435_I550_Y2.7171.00
276_K544_D2.6931.00
252_L270_A2.6911.00
333_K357_P2.6591.00
275_P548_L2.6051.00
241_Y455_H2.5411.00
256_M268_I2.5121.00
387_Q391_K2.5111.00
324_Q481_T2.4941.00
274_D277_T2.4091.00
99_H103_V2.3891.00
340_E345_P2.3831.00
436_Q447_M2.3331.00
449_K471_E2.2961.00
332_E379_K2.2921.00
363_G371_A2.2911.00
361_H491_E2.2631.00
274_D279_K2.2521.00
365_L491_E2.2481.00
71_R245_D2.2331.00
358_T368_S2.2111.00
361_H487_D2.2081.00
362_D366_R2.2071.00
69_L241_Y2.2011.00
329_N332_E2.1781.00
255_S574_P2.1391.00
251_F578_N2.1321.00
258_K574_P2.1301.00
71_R279_K2.1121.00
266_K555_Q2.1031.00
479_A483_K2.1021.00
67_S75_V2.0971.00
362_D365_L2.0641.00
272_V575_T2.0631.00
324_Q478_S2.0631.00
273_V435_I2.0461.00
281_L547_L2.0131.00
573_N577_K2.0131.00
274_D546_E2.0121.00
32_R35_Y2.0101.00
239_N457_V2.0091.00
314_M389_L2.0041.00
547_L579_S1.9901.00
359_T362_D1.9881.00
67_S239_N1.9751.00
145_T148_Q1.9691.00
384_R387_Q1.9641.00
358_T362_D1.9631.00
276_K546_E1.9441.00
317_F437_A1.9241.00
475_T479_A1.9201.00
272_V547_L1.9071.00
355_W368_S1.9071.00
478_S481_T1.9031.00
251_F255_S1.8981.00
248_I579_S1.8901.00
270_A551_V1.8851.00
203_D207_K1.8811.00
202_L240_V1.8651.00
71_R281_L1.8541.00
509_D543_D1.8511.00
321_A388_Y1.8311.00
253_E284_G1.8031.00
248_I281_L1.7991.00
250_T254_D1.7941.00
70_D74_K1.7941.00
365_L495_S1.7871.00
320_A481_T1.7801.00
444_D483_K1.7781.00
511_A539_M1.7661.00
218_D222_W1.7501.00
348_D368_S1.7481.00
491_E495_S1.7401.00
252_L282_A1.7331.00
444_D479_A1.7331.00
444_D486_R1.7321.00
376_A422_A1.7081.00
440_A447_M1.7031.00
439_T548_L1.6951.00
538_G572_F1.6931.00
320_A392_F1.6861.00
121_K125_L1.6861.00
487_D490_G1.6751.00
252_L575_T1.6751.00
572_F576_M1.6711.00
320_A477_I1.6651.00
442_A511_A1.6641.00
75_V78_E1.6641.00
300_Y306_Y1.6531.00
455_H467_Q1.6451.00
438_A489_L1.6411.00
505_I573_N1.6401.00
338_T345_P1.6261.00
184_E195_A1.6101.00
241_Y457_V1.6101.00
553_V571_I1.6031.00
551_V572_F1.5911.00
438_A537_M1.5861.00
316_I441_I1.5851.00
446_K472_S1.5801.00
123_D126_D1.5791.00
257_T286_R1.5761.00
273_V450_P1.5701.00
477_I482_A1.5691.00
374_K379_K1.5651.00
34_A38_I1.5631.00
363_G372_F1.5611.00
199_E210_D1.5511.00
241_Y454_D1.5431.00
490_G494_T1.5281.00
436_Q450_P1.5261.00
431_P550_Y1.5221.00
538_G576_M1.5071.00
320_A485_V1.5071.00
202_L401_D1.5031.00
483_K486_R1.4971.00
519_I554_Q1.4941.00
392_F477_I1.4931.00
493_V512_G1.4931.00
63_A210_D1.4871.00
111_E121_K1.4811.00
120_D123_D1.4681.00
74_K246_Q1.4651.00
100_P103_V1.4611.00
325_E388_Y1.4561.00
493_V510_V1.4561.00
99_H102_H1.4551.00
443_N448_M1.4521.00
272_V579_S1.4431.00
243_T279_K1.4401.00
88_I92_K1.4381.00
280_V452_V1.4351.00
254_D258_K1.4351.00
43_N46_V1.4331.00
328_F360_Y1.4291.00
350_N353_V1.4261.00
540_A580_L1.4151.00
101_Q198_L1.4071.00
460_D463_K1.4061.00
256_M284_G1.4051.00
310_P429_V1.4051.00
254_D578_N1.3981.00
319_L372_F1.3931.00
364_V488_I1.3911.00
339_F374_K1.3901.00
383_D413_K1.3801.00
447_M474_G1.3741.00
89_L102_H1.3721.00
247_K582_Y1.3701.00
376_A385_L1.3631.00
448_M470_P1.3551.00
391_K474_G1.3521.00
328_F332_E1.3481.00
85_L144_I1.3471.00
324_Q391_K1.3441.00
330_A488_I1.3421.00
114_S173_G1.3401.00
274_D281_L1.3341.00
31_G35_Y1.3311.00
273_V548_L1.3171.00
100_P218_D1.3161.00
67_S78_E1.3151.00
113_L117_I1.3131.00
69_L75_V1.3131.00
394_F429_V1.3091.00
248_I282_A1.3071.00
434_Q537_M1.3071.00
141_G148_Q1.3041.00
258_K262_K1.3031.00
340_E343_G1.2971.00
322_A375_L1.2931.00
360_Y371_A1.2751.00
271_A431_P1.2731.00
209_R235_K1.2721.00
334_Y379_K1.2691.00
441_I485_V1.2671.00
125_L129_N1.2671.00
173_G290_D1.2621.00
302_D556_P1.2561.00
494_T504_K1.2561.00
519_I555_Q1.2491.00
492_V500_G1.2481.00
248_I272_V1.2401.00
370_V374_K1.2301.00
451_Y468_N1.2291.00
252_L284_G1.2271.00
112_A115_K1.2241.00
243_T451_Y1.2211.00
493_V536_F1.2181.00
480_S484_K1.2171.00
486_R511_A1.2161.00
89_L173_G1.2121.00
335_K357_P1.2101.00
271_A432_I1.2091.00
179_L244_I1.2031.00
316_I489_L1.2031.00
330_A484_K1.2011.00
273_V439_T1.2011.00
270_A549_I1.2001.00
108_K112_A1.1991.00
386_N390_H1.1891.00
74_K247_K1.1891.00
198_L240_V1.1891.00
283_M303_L1.1801.00
238_D465_I1.1801.00
257_T261_Q1.1781.00
325_E380_L1.1751.00
46_V50_K1.1731.00
457_V464_T1.1691.00
319_L360_Y1.1691.00
414_Y417_D1.1671.00
355_W366_R1.1621.00
89_L177_S1.1571.00
27_F31_G1.1531.00
172_N246_Q1.1491.00
320_A388_Y1.1481.00
271_A435_I1.1471.00
350_N354_G1.1461.00
442_A539_M1.1441.00
500_G503_Y1.1371.00
275_P439_T1.1261.00
35_Y43_N1.1241.00
114_S117_I1.1231.00
313_T434_Q1.1181.00
531_N555_Q1.1171.00
434_Q535_S1.1151.00
358_T366_R1.1131.00
435_I548_L1.1111.00
377_K419_A1.1111.00
578_N581_H1.1091.00
464_T467_Q1.1041.00
227_S230_K1.1041.00
269_M303_L1.1021.00
316_I438_A1.1001.00
549_I576_M1.0991.00
390_H396_Q1.0981.00
317_F389_L1.0961.00
388_Y391_K1.0951.00
112_A116_V1.0951.00
260_A268_I1.0931.00
317_F394_F1.0931.00
273_V436_Q1.0921.00
381_G384_R1.0891.00
257_T265_P1.0861.00
323_M488_I1.0841.00
383_D387_Q1.0831.00
350_N355_W1.0801.00
564_S569_S1.0741.00
324_Q388_Y1.0731.00
580_L583_L1.0731.00
102_H173_G1.0671.00
328_F375_L1.0671.00
123_D127_I1.0541.00
360_Y375_L1.0531.00
551_V571_I1.0521.00
320_A482_A1.0421.00
549_I575_T1.0391.00
24_L28_V1.0381.00
335_K368_S1.0371.00
98_K210_D1.0371.00
547_L583_L1.0351.00
275_P547_L1.0331.00
89_L93_M1.0311.00
121_K124_I1.0271.00
251_F254_D1.0231.00
171_P174_V1.0201.00
107_E125_L1.0191.00
482_A486_R1.0121.00
395_Y433_Q1.0101.00
535_S552_A1.0031.00
32_R36_I1.0031.00
425_Q518_Q1.0011.00
177_S288_S0.9991.00
105_N108_K0.9941.00
327_V379_K0.9931.00
255_S578_N0.9931.00
198_L242_L0.9921.00
534_F564_S0.9901.00
373_A423_Y0.9901.00
453_I456_I0.9901.00
489_L539_M0.9851.00
92_K211_G0.9851.00
269_M431_P0.9841.00
259_V571_I0.9841.00
348_D355_W0.9791.00
101_Q105_N0.9771.00
328_F379_K0.9761.00
534_F562_Q0.9761.00
417_D420_S0.9741.00
335_K348_D0.9741.00
327_V380_L0.9731.00
541_P545_P0.9701.00
246_Q250_T0.9681.00
394_F437_A0.9671.00
122_A126_D0.9641.00
320_A441_I0.9631.00
106_K114_S0.9611.00
546_E583_L0.9601.00
88_I136_E0.9571.00
441_I486_R0.9541.00
364_V489_L0.9531.00
114_S119_L0.9531.00
565_S569_S0.9521.00
388_Y392_F0.9521.00
327_V384_R0.9491.00
255_S258_K0.9481.00
429_V434_Q0.9471.00
355_W358_T0.9461.00
176_A179_L0.9441.00
399_G405_E0.9441.00
388_Y477_I0.9411.00
401_D451_Y0.9411.00
349_H563_S0.9381.00
119_L124_I0.9361.00
252_L272_V0.9321.00
527_D530_D0.9321.00
148_Q151_K0.9301.00
283_M301_N0.9291.00
448_M472_S0.9261.00
322_A328_F0.9231.00
268_I553_V0.9221.00
431_P435_I0.9151.00
267_K302_D0.9151.00
384_R388_Y0.9141.00
442_A548_L0.9141.00
271_A283_M0.9141.00
534_F568_V0.9111.00
398_T405_E0.9101.00
275_P442_A0.9071.00
361_H488_I0.9051.00
455_H464_T0.9031.00
337_G374_K0.9031.00
247_K250_T0.8981.00
260_A286_R0.8981.00
125_L128_L0.8961.00
339_F377_K0.8951.00
68_I79_D0.8941.00
491_E494_T0.8941.00
341_V419_A0.8931.00
483_K487_D0.8821.00
146_Y150_Q0.8811.00
576_M580_L0.8801.00
195_A204_K0.8781.00
72_K245_D0.8781.00
176_A244_I0.8771.00
339_F373_A0.8741.00
434_Q550_Y0.8741.00
35_Y39_T0.8731.00
101_Q218_D0.8721.00
144_I148_Q0.8721.00
283_M452_V0.8711.00
307_A428_A0.8701.00
198_L202_L0.8691.00
333_K359_T0.8671.00
503_Y569_S0.8661.00
117_I121_K0.8651.00
483_K591_S0.8641.00
436_Q449_K0.8621.00
114_S120_D0.8621.00
323_M481_T0.8571.00
358_T371_A0.8551.00
205_Y238_D0.8521.00
84_K165_D0.8491.00
252_L268_I0.8481.00
109_T113_L0.8471.00
486_R489_L0.8471.00
338_T347_K0.8461.00
368_S371_A0.8451.00
64_S236_N0.8451.00
211_G234_P0.8441.00
172_N175_F0.8431.00
406_V430_T0.8411.00
387_Q390_H0.8411.00
481_T485_V0.8411.00
128_L131_D0.8391.00
481_T484_K0.8381.00
149_K153_E0.8381.00
271_A550_Y0.8361.00
130_K139_S0.8351.00
102_H114_S0.8321.00
34_A39_T0.8311.00
141_G150_Q0.8301.00
510_V540_A0.8291.00
73_G454_D0.8291.00
259_V262_K0.8281.00
255_S571_I0.8271.00
109_T112_A0.8271.00
174_V177_S0.8271.00
509_D585_I0.8271.00
256_M270_A0.8261.00
574_P577_K0.8261.00
301_N304_I0.8241.00
321_A380_L0.8241.00
336_S370_V0.8231.00
436_Q439_T0.8221.00
317_F392_F0.8221.00
334_Y374_K0.8211.00
102_H105_N0.8211.00
385_L389_L0.8201.00
394_F434_Q0.8181.00
493_V500_G0.8181.00
85_L160_I0.8181.00
540_A576_M0.8181.00
270_A571_I0.8131.00
87_A160_I0.8121.00
520_A530_D0.8091.00
202_L453_I0.8091.00
205_Y456_I0.8061.00
201_V403_P0.8051.00
110_A114_S0.8051.00
176_A180_I0.8041.00
547_L576_M0.8031.00
277_T448_M0.8021.00
243_T454_D0.8021.00
546_E586_E0.7991.00
147_S151_K0.7981.00
202_L205_Y0.7961.00
184_E194_G0.7951.00
17_I21_C0.7931.00
87_A93_M0.7931.00
209_R212_Y0.7911.00
360_Y488_I0.7901.00
319_L485_V0.7891.00
449_K473_A0.7881.00
307_A406_V0.7870.99
318_T422_A0.7870.99
512_G569_S0.7850.99
553_V568_V0.7840.99
70_D246_Q0.7840.99
549_I572_F0.7840.99
110_A113_L0.7830.99
347_K351_N0.7800.99
238_D456_I0.7790.99
271_A303_L0.7790.99
364_V372_F0.7780.99
248_I575_T0.7770.99
493_V501_Q0.7760.99
176_A253_E0.7740.99
110_A125_L0.7740.99
300_Y305_S0.7710.99
58_K212_Y0.7700.99
139_S142_R0.7640.99
434_Q438_A0.7620.99
380_L384_R0.7610.99
45_E49_T0.7600.99
318_T385_L0.7600.99
150_Q154_K0.7600.99
105_N185_V0.7590.99
116_V167_K0.7580.99
420_S426_A0.7560.99
170_Y178_N0.7530.99
122_A125_L0.7530.99
508_F585_I0.7530.99
321_A325_E0.7520.99
85_L199_E0.7500.99
212_Y232_T0.7500.99
269_M552_A0.7490.99
514_T538_G0.7480.99
500_G536_F0.7440.99
533_I552_A0.7440.99
73_G241_Y0.7430.99
541_P546_E0.7420.99
492_V499_T0.7420.99
337_G356_G0.7410.99
316_I364_V0.7390.99
500_G514_T0.7390.99
317_F434_Q0.7380.99
502_A569_S0.7380.99
563_S566_D0.7370.99
480_S593_S0.7360.99
484_K487_D0.7360.99
444_D482_A0.7360.99
432_I450_P0.7350.99
567_P570_E0.7340.99
534_F565_S0.7330.99
428_A431_P0.7310.99
484_K488_I0.7300.99
501_Q504_K0.7290.99
253_E257_T0.7280.99
346_V420_S0.7270.99
66_G240_V0.7250.99
330_A361_H0.7250.99
107_E117_I0.7240.99
346_V423_Y0.7240.99
334_Y363_G0.7240.99
508_F546_E0.7240.99
400_I452_V0.7210.99
319_L488_I0.7210.99
23_A27_F0.7210.99
430_T433_Q0.7190.99
276_K444_D0.7190.99
105_N109_T0.7180.99
105_N222_W0.7180.99
252_L255_S0.7170.99
280_V283_M0.7170.99
490_G493_V0.7170.99
564_S568_V0.7160.99
495_S501_Q0.7140.99
423_Y518_Q0.7140.99
480_S483_K0.7130.99
564_S570_E0.7130.99
13_R17_I0.7120.99
457_V461_K0.7120.99
313_T537_M0.7120.99
376_A382_Y0.7120.99
576_M579_S0.7120.99
16_A20_I0.7110.99
506_E573_N0.7060.99
240_V456_I0.7050.99
358_T363_G0.7050.99
85_L152_I0.7050.99
33_M36_I0.7040.99
382_Y418_K0.7020.99
107_E110_A0.7010.99
575_T579_S0.6980.99
396_Q433_Q0.6960.99
485_V488_I0.6960.99
84_K163_L0.6950.99
174_V288_S0.6940.99
259_V574_P0.6930.99
553_V567_P0.6900.99
508_F580_L0.6900.99
540_A547_L0.6880.99
280_V400_I0.6880.99
443_N446_K0.6870.99
109_T157_L0.6870.99
372_F422_A0.6850.99
591_S594_D0.6840.99
492_V536_F0.6840.99
361_H365_L0.6840.99
273_V280_V0.6830.99
273_V448_M0.6830.99
273_V550_Y0.6820.99
208_E211_G0.6810.99
533_I554_Q0.6810.99
259_V263_Y0.6800.99
255_S575_T0.6800.99
68_I76_I0.6780.99
183_A225_P0.6770.98
310_P314_M0.6750.98
512_G538_G0.6750.98
440_A476_P0.6740.98
110_A117_I0.6740.98
272_V275_P0.6730.98
536_F572_F0.6720.98
119_L123_D0.6720.98
314_M317_F0.6710.98
109_T114_S0.6700.98
106_K109_T0.6670.98
29_I32_R0.6670.98
534_F567_P0.6660.98
374_K377_K0.6660.98
509_D587_P0.6640.98
244_I452_V0.6620.98
102_H106_K0.6610.98
110_A116_V0.6610.98
318_T376_A0.6610.98
165_D168_R0.6600.98
355_W362_D0.6600.98
346_V373_A0.6600.98
397_K407_S0.6580.98
323_M485_V0.6570.98
107_E111_E0.6560.98
436_Q440_A0.6560.98
263_Y567_P0.6550.98
131_D137_F0.6540.98
458_D465_I0.6520.98
76_I246_Q0.6520.98
510_V536_F0.6510.98
528_G531_N0.6480.98
309_E517_A0.6480.98
402_L452_V0.6480.98
33_M37_Q0.6470.98
311_G517_A0.6470.98
310_P425_Q0.6470.98
323_M329_N0.6460.98
308_Y533_I0.6430.98
543_D588_T0.6410.98
84_K139_S0.6400.98
201_V401_D0.6400.98
21_C25_F0.6400.98
117_I120_D0.6380.98
503_Y512_G0.6370.98
283_M304_I0.6370.98
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134_Q138_G0.6340.98
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514_T572_F0.6310.98
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285_Q303_L0.6290.98
420_S425_Q0.6290.98
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382_Y421_T0.6220.97
209_R232_T0.6210.97
71_R454_D0.6200.97
149_K166_T0.6200.97
532_Y562_Q0.6200.97
350_N368_S0.6180.97
103_V106_K0.6180.97
114_S124_I0.6170.97
214_T230_K0.6170.97
440_A477_I0.6170.97
105_N225_P0.6160.97
88_I177_S0.6130.97
69_L73_G0.6130.97
126_D130_K0.6130.97
289_F292_N0.6130.97
534_F563_S0.6110.97
505_I577_K0.6110.97
469_K472_S0.6080.97
199_E203_D0.6070.97
93_M101_Q0.6070.97
247_K251_F0.6060.97
112_A155_M0.6050.97
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38_I44_G0.6040.97
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20_I24_L0.6030.97
113_L116_V0.6020.97
436_Q448_M0.6020.97
458_D461_K0.6020.97
52_T55_H0.6010.97
381_G418_K0.5990.97
319_L363_G0.5990.97
58_K214_T0.5990.97
184_E196_M0.5980.97
250_T253_E0.5980.97
44_G48_A0.5980.97
328_F334_Y0.5960.97
198_L452_V0.5950.97
425_Q428_A0.5940.97
313_T535_S0.5920.97
347_K354_G0.5910.96
451_Y469_K0.5910.96
398_T430_T0.5910.96
128_L132_A0.5910.96
195_A200_K0.5910.96
86_I161_S0.5900.96
135_V138_G0.5900.96
477_I481_T0.5880.96
325_E328_F0.5870.96
365_L488_I0.5870.96
274_D448_M0.5870.96
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337_G354_G0.5840.96
319_L364_V0.5840.96
339_F370_V0.5830.96
60_T210_D0.5830.96
319_L375_L0.5820.96
446_K470_P0.5820.96
435_I439_T0.5800.96
389_L410_I0.5800.96
67_S79_D0.5800.96
180_I198_L0.5790.96
213_V226_N0.5790.96
344_A420_S0.5780.96
464_T468_N0.5780.96
276_K443_N0.5770.96
580_L585_I0.5770.96
126_D139_S0.5760.96
314_M318_T0.5760.96
48_A52_T0.5760.96
116_V120_D0.5750.96
254_D257_T0.5750.96
354_G370_V0.5740.96
26_F30_L0.5740.96
454_D467_Q0.5740.96
17_I20_I0.5730.96
425_Q517_A0.5730.96
280_V432_I0.5730.96
438_A548_L0.5730.96
98_K101_Q0.5710.96
336_S339_F0.5710.96
134_Q137_F0.5700.96
259_V570_E0.5700.96
447_M450_P0.5700.96
471_E474_G0.5700.96
490_G587_P0.5700.96
360_Y484_K0.5690.96
351_N354_G0.5690.96
416_F419_A0.5690.96
77_A171_P0.5690.96
240_V453_I0.5690.96
196_M289_F0.5680.96
397_K405_E0.5670.96
451_Y454_D0.5660.95
144_I149_K0.5650.95
87_A210_D0.5650.95
441_I477_I0.5650.95
31_G34_A0.5630.95
106_K110_A0.5600.95
508_F577_K0.5600.95
405_E408_S0.5600.95
235_K238_D0.5600.95
281_L454_D0.5570.95
127_I131_D0.5570.95
328_F371_A0.5570.95
43_N47_L0.5550.95
539_M548_L0.5550.95
211_G237_G0.5550.95
308_Y554_Q0.5540.95
179_L283_M0.5530.95
34_A37_Q0.5530.95
321_A385_L0.5530.95
323_M484_K0.5520.95
353_V356_G0.5520.95
332_E371_A0.5510.95
266_K554_Q0.5500.95
276_K448_M0.5500.95
322_A380_L0.5490.95
295_D298_N0.5480.95
157_L160_I0.5470.95
14_G18_L0.5470.95
208_E212_Y0.5470.95
389_L393_N0.5470.95
85_L162_F0.5460.95
318_T389_L0.5460.95
57_K217_S0.5460.95
245_D248_I0.5430.94
316_I485_V0.5430.94
193_S203_D0.5430.94
142_R165_D0.5430.94
107_E113_L0.5420.94
114_S121_K0.5400.94
349_H354_G0.5400.94
177_S289_F0.5390.94
149_K152_I0.5390.94
574_P578_N0.5390.94
271_A548_L0.5380.94
63_A211_G0.5380.94
372_F375_L0.5380.94
119_L127_I0.5360.94
551_V568_V0.5360.94
200_K403_P0.5360.94
165_D169_Y0.5360.94
394_F433_Q0.5350.94
269_M285_Q0.5350.94
201_V205_Y0.5350.94
109_T117_I0.5350.94
294_R298_N0.5340.94
376_A421_T0.5320.94
49_T53_E0.5310.94
503_Y565_S0.5310.94
439_T448_M0.5310.94
205_Y466_Y0.5300.94
540_A545_P0.5300.94
144_I183_A0.5300.94
386_N412_F0.5290.94
429_V437_A0.5290.94
35_Y38_I0.5290.94
349_H355_W0.5280.94
78_E169_Y0.5280.94
80_T143_D0.5270.93
547_L580_L0.5270.93
437_A440_A0.5260.93
553_V565_S0.5260.93
502_A566_D0.5260.93
482_A485_V0.5250.93
393_N447_M0.5230.93
441_I489_L0.5230.93
579_S583_L0.5230.93
175_F253_E0.5230.93
298_N302_D0.5220.93
124_I128_L0.5220.93
392_F440_A0.5220.93
216_E225_P0.5220.93
196_M200_K0.5220.93
174_V253_E0.5210.93
143_D167_K0.5210.93
304_I404_G0.5210.93
309_E533_I0.5170.93
104_V107_E0.5150.93
252_L549_I0.5150.93
258_K261_Q0.5130.93
59_R213_V0.5130.93
510_V572_F0.5110.92
306_Y430_T0.5110.92
72_K247_K0.5110.92
30_L33_M0.5110.92
86_I165_D0.5100.92
451_Y470_P0.5100.92
380_L388_Y0.5090.92
380_L385_L0.5080.92
317_F438_A0.5080.92
110_A121_K0.5080.92
109_T116_V0.5070.92
585_I588_T0.5070.92
186_D195_A0.5070.92
100_P215_Y0.5060.92
185_V198_L0.5060.92
253_E286_R0.5060.92
480_S594_D0.5050.92
137_F140_A0.5040.92
187_E195_A0.5040.92
22_F38_I0.5040.92
316_I437_A0.5030.92
259_V553_V0.5030.92
110_A115_K0.5020.92
510_V573_N0.5020.92
348_D351_N0.5020.92
32_R38_I0.5020.92
506_E509_D0.5010.92
538_G551_V0.5010.92
124_I127_I0.5000.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1qmeA 1 0.75 100 0.228 Contact Map
4ye5A 1 0.7332 100 0.322 Contact Map
4ovdA 2 0.5754 100 0.327 Contact Map
3equA 1 0.595 100 0.333 Contact Map
2wadA 1 0.6955 100 0.338 Contact Map
3ue3A 1 0.5964 100 0.359 Contact Map
4oonA 1 0.4888 100 0.362 Contact Map
4bjpA 2 0.5628 100 0.364 Contact Map
3pbtA 1 0.6872 100 0.366 Contact Map
3udfA 2 0.5796 100 0.367 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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