GREMLIN Database
FTSL - Cell division protein FtsL
UniProt: Q07867 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 117 (111)
Sequences: 185 (155)
Seq/√Len: 14.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
76_E80_I3.4880.99
93_P115_I3.3030.99
56_A105_L2.6280.95
103_N114_N2.5920.94
80_I89_D2.4650.93
24_V45_V2.3350.91
86_S89_D2.2650.89
82_D105_L2.1870.87
107_L114_N1.9820.82
82_D93_P1.9200.79
99_I109_D1.8920.78
93_P111_K1.8630.77
93_P97_M1.8590.77
90_L95_R1.8470.77
13_R18_P1.8340.76
56_A59_A1.7800.74
35_K101_K1.7410.72
60_Y107_L1.6510.68
10_K94_Q1.6240.67
22_V25_K1.5700.64
30_I38_L1.5580.63
108_K111_K1.5470.63
19_E23_I1.5210.61
36_V74_S1.5040.60
60_Y76_E1.4670.58
41_F105_L1.4290.56
33_G79_Q1.3650.53
31_T35_K1.3470.52
39_V66_V1.3400.51
67_Q89_D1.3200.50
56_A93_P1.3130.50
53_V79_Q1.3120.50
46_L53_V1.3100.50
81_G99_I1.2990.49
33_G73_I1.2840.48
55_K110_K1.2820.48
99_I115_I1.2620.47
29_S65_E1.2550.47
59_A69_L1.2470.46
95_R112_V1.2150.45
13_R73_I1.2060.44
39_V81_G1.1970.44
93_P99_I1.1950.43
8_P69_L1.1750.42
27_R38_L1.1530.41
82_D85_K1.1520.41
39_V97_M1.1280.40
59_A66_V1.1280.40
33_G86_S1.1230.40
84_E106_N1.1200.39
46_L50_L1.1070.39
78_K82_D1.0820.37
45_V92_K1.0320.35
50_L105_L1.0300.35
60_Y114_N1.0170.34
30_I33_G1.0140.34
53_V101_K1.0130.34
6_Y32_L1.0110.34
90_L94_Q1.0050.33
63_N67_Q1.0020.33
15_A37_L0.9860.33
55_K60_Y0.9740.32
61_Q81_G0.9680.32
43_A79_Q0.9590.31
88_A105_L0.9410.30
6_Y64_I0.9350.30
97_M107_L0.9260.30
55_K76_E0.9220.30
65_E112_V0.9160.29
56_A67_Q0.9140.29
26_K77_N0.9130.29
17_S65_E0.9120.29
47_S72_Q0.9090.29
30_I58_A0.9050.29
7_Q77_N0.9020.29
27_R46_L0.9000.28
26_K105_L0.8990.28
20_K23_I0.8980.28
90_L112_V0.8730.27
30_I97_M0.8730.27
99_I111_K0.8610.27
20_K42_A0.8590.27
56_A78_K0.8570.27
93_P96_I0.8480.26
87_V103_N0.8450.26
56_A111_K0.8360.26
32_L48_V0.8220.25
82_D113_K0.8190.25
13_R102_K0.8130.25
25_K50_L0.8060.24
74_S101_K0.8030.24
36_V71_E0.7760.23
25_K42_A0.7750.23
25_K69_L0.7750.23
33_G89_D0.7690.23
92_K96_I0.7650.23
98_D102_K0.7510.22
68_K84_E0.7490.22
24_V106_N0.7390.22
37_L73_I0.7390.22
53_V60_Y0.7300.21
50_L79_Q0.7120.21
92_K105_L0.7080.21
23_I47_S0.7060.21
78_K105_L0.6960.20
87_V97_M0.6890.20
87_V94_Q0.6870.20
31_T37_L0.6870.20
21_K63_N0.6840.20
51_L93_P0.6830.20
39_V71_E0.6750.19
11_Q15_A0.6730.19
5_A53_V0.6620.19
33_G63_N0.6590.19
13_R96_I0.6570.19
67_Q70_E0.6530.19
17_S72_Q0.6510.19
52_I86_S0.6490.19
19_E112_V0.6480.19
66_V106_N0.6480.19
68_K71_E0.6450.18
109_D115_I0.6380.18
58_A90_L0.6300.18
21_K50_L0.6290.18
26_K70_E0.6210.18
11_Q94_Q0.6140.17
13_R16_I0.6110.17
38_L48_V0.6050.17
32_L46_L0.6030.17
69_L96_I0.6000.17
31_T34_E0.5940.17
14_H71_E0.5940.17
15_A52_I0.5860.17
17_S77_N0.5860.17
85_K105_L0.5850.17
41_F93_P0.5830.16
14_H66_V0.5810.16
60_Y85_K0.5780.16
11_Q84_E0.5780.16
13_R23_I0.5770.16
56_A85_K0.5760.16
37_L65_E0.5750.16
41_F82_D0.5710.16
36_V86_S0.5710.16
88_A92_K0.5660.16
77_N106_N0.5660.16
66_V72_Q0.5630.16
18_P24_V0.5630.16
30_I61_Q0.5620.16
13_R17_S0.5560.16
76_E79_Q0.5560.16
44_A84_E0.5550.16
63_N79_Q0.5510.15
20_K98_D0.5480.15
28_A109_D0.5400.15
27_R103_N0.5370.15
38_L51_L0.5250.15
44_A110_K0.5200.15
7_Q65_E0.5190.15
99_I107_L0.5150.14
12_Q109_D0.5140.14
40_L69_L0.5120.14
80_I91_S0.5110.14
56_A114_N0.5060.14
60_Y113_K0.5030.14
21_K37_L0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4cgkA 3 0.359 33 0.923 Contact Map
4q4gX 1 0 27.3 0.926 Contact Map
3ghgA 2 0.8718 26.8 0.926 Contact Map
1a93B 1 0.2735 25 0.927 Contact Map
3viqB 1 0.453 16.7 0.933 Contact Map
1rz2A 1 0.4872 11.7 0.937 Contact Map
4etpA 1 0.5299 11.5 0.937 Contact Map
3vn0A 2 0.3504 9.9 0.939 Contact Map
1deqA 1 0.8718 9.1 0.94 Contact Map
4dznA 3 0.265 8.8 0.941 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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