GREMLIN Database
SECE - Protein translocase subunit SecE
UniProt: Q06799 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 59 (55)
Sequences: 170 (111)
Seq/√Len: 14.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
18_S21_K3.0560.98
16_K40_V2.2410.89
15_K56_L2.1830.88
26_T30_I2.1490.87
14_M18_S2.1000.86
10_V14_M2.0780.85
23_K26_T1.7920.75
17_V45_L1.7150.72
51_S55_R1.7080.71
45_L48_T1.6090.67
14_M27_R1.5560.64
34_S37_I1.5280.62
52_Q55_R1.5040.61
8_K41_I1.3990.55
54_I58_V1.3560.53
10_V18_S1.3120.51
33_I52_Q1.2830.49
21_K39_F1.2550.47
54_I57_I1.2540.47
31_T51_S1.1750.43
38_F52_Q1.1550.42
4_M11_G1.1520.42
31_T53_L1.1520.42
9_D31_T1.1420.41
44_A51_S1.1310.41
4_M54_I1.1050.39
26_T34_S1.1030.39
23_K28_Y1.0580.37
30_I34_S1.0550.36
39_F46_L1.0320.35
8_K17_V1.0300.35
5_K18_S1.0080.34
55_R58_V0.9960.33
15_K53_L0.9700.32
12_K15_K0.9530.31
10_V25_L0.9380.31
5_K46_L0.8790.28
5_K8_K0.8760.28
16_K21_K0.8730.28
11_G14_M0.8660.27
48_T55_R0.8660.27
31_T42_F0.8570.27
41_I44_A0.8060.25
37_I56_L0.7990.24
38_F56_L0.7910.24
16_K31_T0.7830.24
7_F43_F0.7670.23
5_K42_F0.7670.23
8_K46_L0.7560.23
8_K55_R0.7550.23
22_G50_I0.7370.22
30_I40_V0.7350.22
39_F54_I0.7340.22
4_M9_D0.7270.22
4_M21_K0.7180.21
4_M39_F0.6950.20
23_K45_L0.6930.20
9_D51_S0.6840.20
15_K22_G0.6750.20
30_I33_I0.6440.19
27_R38_F0.6400.18
11_G58_V0.6310.18
8_K44_A0.6260.18
35_T49_G0.6210.18
35_T55_R0.6130.18
15_K21_K0.5970.17
22_G39_F0.5970.17
7_F34_S0.5960.17
17_V27_R0.5720.16
41_I53_L0.5690.16
13_E49_G0.5390.15
35_T48_T0.5370.15
7_F11_G0.5350.15
13_E50_I0.5260.15
21_K27_R0.5230.15
27_R50_I0.5220.15
35_T51_S0.5160.15
27_R41_I0.5160.15
16_K30_I0.5060.14
21_K26_T0.5010.14
21_K34_S0.5000.14
8_K22_G0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j01B 1 1 99.6 0.393 Contact Map
3dl8C 1 0.5593 99.6 0.394 Contact Map
3dinD 1 0.8644 99.6 0.395 Contact Map
2zjsE 1 0.7797 99.6 0.411 Contact Map
3bo0B 1 1 99.3 0.507 Contact Map
3nymA 2 0.3898 37.7 0.878 Contact Map
1rh5B 1 0.9492 27.7 0.885 Contact Map
2ww9B 1 0.9322 18.8 0.894 Contact Map
4w252 1 1 16.7 0.897 Contact Map
3mp7B 1 0.8305 8.1 0.91 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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