GREMLIN Database
RL332 - 50S ribosomal protein L33 2
UniProt: Q06798 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 49 (49)
Sequences: 240 (90)
Seq/√Len: 12.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
14_N38_T5.1651.00
33_K41_S2.7070.94
11_T41_S2.5580.92
32_V35_Y1.9190.74
3_K23_S1.8180.70
35_Y40_N1.7680.68
26_A30_L1.5790.59
20_M25_S1.5360.57
3_K24_A1.5300.56
4_K18_T1.4610.53
5_I30_L1.4570.53
13_G42_H1.4270.51
4_K20_M1.3400.47
19_T30_L1.3140.45
24_A48_T1.2900.44
37_S44_A1.2860.44
23_S49_K1.2280.41
2_R28_E1.2200.40
13_G38_T1.2190.40
29_R46_L1.1870.39
8_A13_G1.1690.38
22_S32_V1.1650.38
2_R8_A1.1420.37
19_T25_S1.1400.36
13_G39_C1.1130.35
22_S30_L1.0730.33
39_C42_H0.9960.30
4_K14_N0.9530.28
8_A35_Y0.9110.26
11_T43_T0.8660.24
33_K44_A0.8630.24
18_T49_K0.8370.23
22_S26_A0.8320.23
20_M49_K0.8300.23
6_T13_G0.8160.23
11_T29_R0.8060.22
30_L40_N0.7980.22
10_K46_L0.7460.20
7_L35_Y0.7450.20
4_K46_L0.7420.20
25_S44_A0.7210.19
24_A27_A0.7070.19
6_T44_A0.6900.18
24_A40_N0.6610.17
1_M23_S0.6570.17
30_L37_S0.6570.17
28_E39_C0.6550.17
3_K18_T0.6430.17
26_A29_R0.6400.17
19_T41_S0.6390.17
18_T26_A0.6360.17
14_N24_A0.6290.16
23_S35_Y0.6270.16
5_I19_T0.6180.16
11_T49_K0.6170.16
14_N39_C0.6090.16
14_N30_L0.6060.16
8_A37_S0.6020.16
21_K26_A0.5950.16
18_T33_K0.5950.16
26_A32_V0.5940.16
4_K29_R0.5760.15
2_R10_K0.5750.15
1_M46_L0.5730.15
32_V46_L0.5630.15
10_K24_A0.5610.15
18_T30_L0.5490.14
33_K48_T0.5430.14
11_T28_E0.5340.14
40_N46_L0.5280.14
6_T32_V0.5230.14
6_T35_Y0.5130.13
6_T20_M0.5100.13
8_A14_N0.5000.13
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1nkw1 1 1 99.8 0.193 Contact Map
4rb66 1 1 99.8 0.201 Contact Map
4tp91 1 1 99.8 0.205 Contact Map
3bbo3 1 1 99.8 0.211 Contact Map
2zjr1 1 1 99.8 0.212 Contact Map
3j7y1 1 0.9592 99.7 0.269 Contact Map
1vw4X 1 0.9592 99.7 0.282 Contact Map
3j21j 1 0.4898 83.6 0.816 Contact Map
1vq83 1 0.4898 83.2 0.817 Contact Map
3j39o 1 0.5102 77 0.828 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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