SYC - BACSU - GREMLIN Contacts

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SYC - Cysteine--tRNA ligase

UniProt:	Q06752	Sequences: MTITLYNTLTRQKETFVPLEEGKVKMYVCGPTVYNYIHIGNARPAIVYDTVRNYLEYKGYDVQYVSNFTDVDDKLIKAANELGEDVPTISERFIKAYFEDVGALGCRKADLHPRVMENMDAIIEFVDQLVKKGYAYESEGDVYFKTRAFEGYGKLSQQSIDELRSGARIRVGEKKEDALDFALWKAAKEGEISWDSPWGKGRPGWHIECSAMVKKYLGDQIDIHAGGQDLTFPHHENEIAQSEALTGKTFAKYWLHNGYINIDNEKMSKSLGNFVLVHDIIKQHDPQLLRFFMLSVHYRHPINYSEELLENTKSAFSRLKTAYSNLQHRLNSSTNLTEDDDQWLEKVEEHRKAFEEEMDDDFNTANAISVLFDLAKHANYYLQKDHTADHVITAFIEMFDRIVSVLGFSLGEQELLDQEIEDLIEKRNEARRNRDFALSDQIRDQLKSMNIILEDTAQGTRWKRGE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	466 (421)
Sequences:	20262 (11242)
Seq/√Len:	547.9

ECOLI - SYC SYM SYV SYI SYL
BACSU - SYC SYM SYV SYI SYL
HALSA - SYC SYM SYV SYL SYI
SULSO - SYC SYM SYV SYL2 SYL1 SYI

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
55_L	60_Y	5.544	1.00
127_D	131_K	3.938	1.00
58_K	355_E	3.861	1.00
353_A	370_V	3.837	1.00
85_D	88_T	3.387	1.00
145_K	148_A	3.269	1.00
36_Y	96_A	3.177	1.00
283_Q	306_E	3.131	1.00
128_Q	131_K	3.114	1.00
50_T	294_L	3.053	1.00
429_E	433_N	2.931	1.00
265_E	271_L	2.931	1.00
23_K	61_D	2.916	1.00
78_A	81_E	2.915	1.00
132_K	244_A	2.882	1.00
56_E	107_R	2.876	1.00
134_Y	148_A	2.742	1.00
82_L	92_R	2.725	1.00
102_G	108_K	2.696	1.00
145_K	176_E	2.630	1.00
96_A	99_E	2.607	1.00
400_D	404_S	2.554	1.00
352_K	356_E	2.520	1.00
128_Q	132_K	2.495	1.00
397_E	401_R	2.409	1.00
87_P	91_E	2.392	1.00
356_E	361_D	2.371	1.00
58_K	359_D	2.338	1.00
363_N	366_N	2.329	1.00
124_E	128_Q	2.318	1.00
95_K	99_E	2.249	1.00
52_R	56_E	2.219	1.00
84_E	92_R	2.189	1.00
54_Y	58_K	2.184	1.00
176_E	179_L	2.142	1.00
55_L	58_K	2.142	1.00
370_V	373_D	2.142	1.00
125_F	245_L	2.122	1.00
195_D	200_K	2.088	1.00
98_F	102_G	2.045	1.00
222_D	251_A	1.973	1.00
84_E	88_T	1.962	1.00
357_E	366_N	1.938	1.00
346_K	377_H	1.926	1.00
103_A	282_K	1.924	1.00
401_R	408_F	1.915	1.00
279_D	282_K	1.886	1.00
405_V	408_F	1.882	1.00
400_D	405_V	1.873	1.00
48_Y	225_A	1.866	1.00
425_E	429_E	1.861	1.00
52_R	62_V	1.847	1.00
121_A	215_K	1.834	1.00
99_E	103_A	1.804	1.00
91_E	95_K	1.790	1.00
349_E	353_A	1.767	1.00
404_S	407_G	1.730	1.00
278_H	282_K	1.725	1.00
357_E	370_V	1.716	1.00
84_E	89_I	1.700	1.00
392_I	395_F	1.695	1.00
350_H	374_L	1.680	1.00
422_D	426_K	1.674	1.00
129_L	244_A	1.666	1.00
390_H	394_A	1.656	1.00
401_R	405_V	1.651	1.00
401_R	404_S	1.649	1.00
54_Y	355_E	1.602	1.00
428_N	432_R	1.597	1.00
51_V	362_F	1.579	1.00
393_T	397_E	1.575	1.00
346_K	349_E	1.574	1.00
421_E	425_E	1.571	1.00
113_P	116_M	1.549	1.00
95_K	98_F	1.520	1.00
159_S	162_E	1.511	1.00
280_I	289_L	1.508	1.00
391_V	394_A	1.491	1.00
189_E	192_I	1.489	1.00
345_E	349_E	1.479	1.00
306_E	310_E	1.470	1.00
397_E	400_D	1.467	1.00
400_D	403_V	1.465	1.00
45_A	101_V	1.461	1.00
252_K	362_F	1.447	1.00
262_I	305_S	1.441	1.00
191_E	194_W	1.437	1.00
276_L	279_D	1.434	1.00
20_E	23_K	1.420	1.00
355_E	359_D	1.419	1.00
20_E	25_K	1.406	1.00
76_I	80_N	1.404	1.00
400_D	407_G	1.403	1.00
112_H	115_V	1.403	1.00
26_M	52_R	1.396	1.00
422_D	425_E	1.391	1.00
288_L	313_K	1.390	1.00
88_T	92_R	1.386	1.00
184_W	187_A	1.385	1.00
103_A	281_I	1.381	1.00
188_K	191_E	1.365	1.00
410_L	413_Q	1.359	1.00
211_A	214_K	1.355	1.00
205_W	208_E	1.355	1.00
78_A	82_L	1.350	1.00
27_Y	30_G	1.336	1.00
353_A	356_E	1.334	1.00
416_L	419_E	1.331	1.00
358_M	367_A	1.326	1.00
219_D	248_K	1.316	1.00
386_H	389_D	1.314	1.00
214_K	217_L	1.307	1.00
213_V	217_L	1.291	1.00
46_I	293_M	1.283	1.00
191_E	195_D	1.282	1.00
68_F	94_I	1.281	1.00
396_I	399_F	1.279	1.00
351_R	355_E	1.276	1.00
318_R	375_A	1.273	1.00
89_I	93_F	1.268	1.00
77_K	81_E	1.266	1.00
190_G	194_W	1.255	1.00
348_E	351_R	1.250	1.00
68_F	98_F	1.247	1.00
213_V	216_Y	1.246	1.00
208_E	211_A	1.246	1.00
103_A	278_H	1.244	1.00
151_G	154_K	1.243	1.00
394_A	405_V	1.241	1.00
189_E	194_W	1.239	1.00
380_Y	384_K	1.237	1.00
183_L	186_A	1.233	1.00
390_H	393_T	1.233	1.00
393_T	396_I	1.220	1.00
211_A	215_K	1.218	1.00
429_E	432_R	1.218	1.00
307_E	310_E	1.217	1.00
404_S	408_F	1.215	1.00
210_S	214_K	1.214	1.00
147_R	177_D	1.212	1.00
338_E	341_D	1.205	1.00
176_E	180_D	1.203	1.00
346_K	350_H	1.201	1.00
209_C	212_M	1.198	1.00
18_P	21_E	1.198	1.00
340_D	381_Y	1.198	1.00
193_S	196_S	1.197	1.00
190_G	193_S	1.195	1.00
192_I	195_D	1.195	1.00
128_Q	245_L	1.194	1.00
279_D	283_Q	1.191	1.00
186_A	189_E	1.180	1.00
235_H	253_Y	1.180	1.00
99_E	102_G	1.177	1.00
403_V	407_G	1.173	1.00
99_E	278_H	1.170	1.00
402_I	405_V	1.169	1.00
45_A	106_C	1.168	1.00
44_P	257_N	1.166	1.00
391_V	395_F	1.160	1.00
70_D	114_R	1.158	1.00
27_Y	34_Y	1.154	1.00
127_D	130_V	1.150	1.00
54_Y	358_M	1.148	1.00
398_M	402_I	1.139	1.00
180_D	184_W	1.134	1.00
189_E	193_S	1.134	1.00
184_W	188_K	1.123	1.00
92_R	96_A	1.120	1.00
354_F	367_A	1.117	1.00
346_K	376_K	1.114	1.00
418_Q	422_D	1.112	1.00
341_D	345_E	1.104	1.00
347_V	351_R	1.103	1.00
209_C	216_Y	1.103	1.00
262_I	307_E	1.102	1.00
42_A	104_L	1.099	1.00
36_Y	278_H	1.097	1.00
162_E	165_S	1.095	1.00
283_Q	310_E	1.089	1.00
54_Y	359_D	1.089	1.00
52_R	107_R	1.084	1.00
207_I	210_S	1.083	1.00
109_A	112_H	1.077	1.00
22_G	60_Y	1.077	1.00
287_Q	320_K	1.076	1.00
191_E	196_S	1.074	1.00
124_E	127_D	1.065	1.00
337_T	340_D	1.062	1.00
322_A	375_A	1.061	1.00
180_D	183_L	1.060	1.00
351_R	401_R	1.060	1.00
208_E	213_V	1.057	1.00
219_D	222_D	1.055	1.00
399_F	402_I	1.052	1.00
210_S	213_V	1.049	1.00
209_C	213_V	1.049	1.00
350_H	370_V	1.048	1.00
392_I	396_I	1.048	1.00
108_K	111_L	1.047	1.00
30_G	34_Y	1.047	1.00
397_E	405_V	1.043	1.00
108_K	112_H	1.039	1.00
180_D	188_K	1.039	1.00
206_H	209_C	1.037	1.00
354_F	358_M	1.036	1.00
307_E	311_N	1.035	1.00
347_V	374_L	1.034	1.00
394_A	398_M	1.030	1.00
181_F	184_W	1.027	1.00
191_E	197_P	1.024	1.00
118_N	216_Y	1.019	1.00
313_K	317_S	1.015	1.00
212_M	216_Y	1.014	1.00
190_G	196_S	1.014	1.00
29_C	34_Y	1.012	1.00
134_Y	244_A	1.008	1.00
118_N	121_A	1.008	1.00
190_G	195_D	1.008	1.00
292_F	308_L	1.006	1.00
37_I	41_N	1.006	1.00
31_P	34_Y	1.005	1.00
100_D	278_H	1.002	1.00
94_I	98_F	0.999	1.00
98_F	110_D	0.998	1.00
35_N	41_N	0.997	1.00
194_W	197_P	0.995	1.00
51_V	55_L	0.987	1.00
322_A	378_A	0.982	1.00
261_N	303_N	0.982	1.00
394_A	397_E	0.982	1.00
267_M	273_N	0.982	1.00
91_E	114_R	0.981	1.00
98_F	112_H	0.976	1.00
24_V	60_Y	0.976	1.00
423_L	426_K	0.972	1.00
417_D	421_E	0.971	1.00
413_Q	416_L	0.964	1.00
202_R	205_W	0.963	1.00
168_R	171_V	0.959	1.00
391_V	408_F	0.955	1.00
394_A	407_G	0.955	1.00
50_T	358_M	0.954	1.00
425_E	428_N	0.954	1.00
366_N	369_S	0.953	1.00
347_V	401_R	0.943	1.00
398_M	401_R	0.943	1.00
395_F	398_M	0.942	1.00
357_E	367_A	0.939	1.00
211_A	216_Y	0.935	1.00
212_M	215_K	0.934	1.00
353_A	357_E	0.933	1.00
430_A	433_N	0.931	1.00
354_F	371_L	0.931	1.00
82_L	89_I	0.930	1.00
108_K	113_P	0.928	1.00
264_N	303_N	0.927	1.00
75_L	86_V	0.926	1.00
88_T	91_E	0.920	1.00
98_F	108_K	0.919	1.00
419_E	435_D	0.914	1.00
315_A	372_F	0.914	1.00
231_T	255_L	0.907	1.00
120_D	123_I	0.905	1.00
57_Y	404_S	0.903	1.00
129_L	241_Q	0.901	1.00
129_L	132_K	0.900	1.00
176_E	181_F	0.899	1.00
400_D	408_F	0.886	1.00
369_S	373_D	0.885	1.00
182_A	185_K	0.884	1.00
348_E	352_K	0.883	1.00
121_A	124_E	0.879	1.00
180_D	186_A	0.878	1.00
35_N	78_A	0.878	1.00
426_K	430_A	0.877	1.00
344_L	348_E	0.867	1.00
418_Q	421_E	0.867	1.00
390_H	395_F	0.864	1.00
179_L	183_L	0.863	1.00
216_Y	242_S	0.862	1.00
209_C	215_K	0.861	1.00
153_G	156_S	0.858	1.00
192_I	196_S	0.853	1.00
165_S	168_R	0.852	1.00
161_D	168_R	0.851	1.00
395_F	408_F	0.850	1.00
354_F	370_V	0.841	1.00
51_V	223_I	0.839	1.00
202_R	206_H	0.837	1.00
349_E	352_K	0.835	1.00
178_A	181_F	0.833	1.00
344_L	394_A	0.832	1.00
120_D	124_E	0.832	1.00
378_A	395_F	0.825	1.00
144_F	149_F	0.824	1.00
193_S	200_K	0.824	1.00
186_A	190_G	0.822	1.00
415_L	418_Q	0.822	1.00
393_T	405_V	0.822	1.00
193_S	198_W	0.820	1.00
185_K	188_K	0.819	1.00
44_P	256_H	0.819	1.00
267_M	274_F	0.817	1.00
55_L	359_D	0.817	1.00
48_Y	64_Y	0.817	1.00
399_F	408_F	0.812	1.00
193_S	197_P	0.812	1.00
285_D	288_L	0.808	1.00
175_K	178_A	0.808	1.00
93_F	96_A	0.805	1.00
342_Q	346_K	0.804	1.00
262_I	274_F	0.799	1.00
123_I	127_D	0.798	1.00
248_K	251_A	0.797	1.00
167_A	170_R	0.797	1.00
28_V	225_A	0.794	1.00
353_A	366_N	0.791	1.00
249_T	252_K	0.790	1.00
428_N	431_R	0.790	1.00
411_G	414_E	0.787	1.00
183_L	187_A	0.787	1.00
92_R	95_K	0.782	1.00
192_I	197_P	0.782	1.00
194_W	199_G	0.780	1.00
132_K	246_T	0.777	1.00
213_V	221_I	0.775	1.00
412_E	415_L	0.775	1.00
402_I	407_G	0.775	1.00
219_D	242_S	0.774	1.00
310_E	314_S	0.774	1.00
183_L	188_K	0.773	1.00
169_I	172_G	0.773	1.00
403_V	408_F	0.771	1.00
183_L	190_G	0.771	1.00
109_A	115_V	0.769	1.00
397_E	408_F	0.769	1.00
193_S	199_G	0.769	1.00
36_Y	93_F	0.768	1.00
208_E	212_M	0.766	1.00
43_R	302_I	0.765	1.00
177_D	180_D	0.765	1.00
377_H	380_Y	0.764	1.00
396_I	407_G	0.764	1.00
336_L	344_L	0.763	1.00
49_D	53_N	0.763	1.00
281_I	286_P	0.763	1.00
393_T	408_F	0.761	1.00
353_A	373_D	0.757	1.00
396_I	403_V	0.756	1.00
46_I	106_C	0.756	1.00
158_Q	163_L	0.755	1.00
396_I	400_D	0.755	1.00
415_L	419_E	0.753	1.00
189_E	196_S	0.753	1.00
118_N	201_G	0.753	1.00
218_G	222_D	0.752	1.00
419_E	423_L	0.751	1.00
139_E	173_E	0.751	1.00
403_V	406_L	0.748	1.00
115_V	122_I	0.747	1.00
25_K	34_Y	0.744	1.00
427_R	431_R	0.742	1.00
391_V	397_E	0.742	1.00
342_Q	345_E	0.741	1.00
152_Y	155_L	0.741	1.00
37_I	100_D	0.741	1.00
52_R	64_Y	0.740	1.00
357_E	361_D	0.739	1.00
271_L	274_F	0.735	1.00
350_H	354_F	0.734	1.00
291_F	312_T	0.734	1.00
336_L	341_D	0.732	1.00
202_R	210_S	0.732	1.00
75_L	90_S	0.729	1.00
345_E	348_E	0.728	1.00
424_I	428_N	0.727	1.00
51_V	364_T	0.725	1.00
257_N	260_I	0.723	1.00
175_K	182_A	0.723	1.00
430_A	434_R	0.722	1.00
223_I	362_F	0.719	1.00
204_G	207_I	0.718	1.00
223_I	254_W	0.717	1.00
180_D	185_K	0.716	1.00
53_N	107_R	0.712	1.00
25_K	63_Q	0.711	1.00
167_A	171_V	0.709	1.00
391_V	396_I	0.708	1.00
134_Y	186_A	0.708	1.00
36_Y	100_D	0.708	1.00
130_V	135_A	0.707	1.00
166_G	169_I	0.706	1.00
291_F	368_I	0.705	1.00
109_A	117_E	0.702	1.00
319_L	375_A	0.700	1.00
397_E	403_V	0.700	1.00
342_Q	377_H	0.695	1.00
28_V	34_Y	0.694	1.00
176_E	183_L	0.694	1.00
414_E	417_D	0.693	1.00
46_I	294_L	0.693	1.00
82_L	85_D	0.691	1.00
397_E	404_S	0.690	1.00
358_M	406_L	0.689	1.00
325_N	383_Q	0.688	1.00
111_L	117_E	0.688	1.00
181_F	185_K	0.688	1.00
310_E	313_K	0.687	1.00
228_Q	259_Y	0.686	1.00
46_I	50_T	0.686	1.00
412_E	416_L	0.685	1.00
24_V	29_C	0.685	1.00
28_V	48_Y	0.684	1.00
399_F	404_S	0.684	1.00
20_E	61_D	0.683	1.00
397_E	407_G	0.683	1.00
209_C	214_K	0.681	1.00
226_G	235_H	0.681	1.00
61_D	218_G	0.680	1.00
350_H	353_A	0.678	1.00
308_L	311_N	0.678	1.00
41_N	45_A	0.677	1.00
380_Y	383_Q	0.677	1.00
423_L	427_R	0.676	1.00
78_A	89_I	0.675	1.00
175_K	181_F	0.672	1.00
113_P	117_E	0.671	1.00
352_K	355_E	0.669	1.00
392_I	399_F	0.668	1.00
39_I	274_F	0.667	1.00
72_D	76_I	0.666	1.00
105_G	286_P	0.666	1.00
25_K	29_C	0.666	1.00
383_Q	386_H	0.665	1.00
343_W	377_H	0.664	1.00
357_E	363_N	0.663	1.00
264_N	272_G	0.662	1.00
177_D	181_F	0.661	1.00
110_D	113_P	0.660	1.00
190_G	197_P	0.659	1.00
291_F	315_A	0.659	1.00
141_D	175_K	0.657	1.00
177_D	183_L	0.657	1.00
50_T	364_T	0.653	1.00
223_I	252_K	0.653	1.00
211_A	217_L	0.652	1.00
220_Q	252_K	0.651	1.00
24_V	27_Y	0.650	1.00
201_G	206_H	0.649	1.00
42_A	277_V	0.648	1.00
391_V	400_D	0.648	1.00
411_G	415_L	0.647	1.00
263_D	303_N	0.647	1.00
143_Y	157_Q	0.646	1.00
101_V	106_C	0.643	1.00
94_I	114_R	0.643	1.00
100_D	276_L	0.642	1.00
393_T	407_G	0.642	1.00
267_M	275_V	0.641	1.00
29_C	32_T	0.640	1.00
214_K	246_T	0.640	1.00
258_G	261_N	0.640	1.00
182_A	186_A	0.639	1.00
224_H	238_E	0.637	1.00
432_R	436_F	0.637	1.00
391_V	407_G	0.636	1.00
391_V	404_S	0.636	1.00
95_K	102_G	0.636	1.00
431_R	436_F	0.632	1.00
210_S	216_Y	0.632	1.00
420_I	423_L	0.632	1.00
195_D	198_W	0.630	1.00
195_D	199_G	0.629	1.00
47_V	294_L	0.629	1.00
391_V	398_M	0.627	1.00
179_L	182_A	0.624	1.00
51_V	255_L	0.623	1.00
24_V	34_Y	0.622	1.00
82_L	93_F	0.621	1.00
208_E	216_Y	0.619	1.00
181_F	188_K	0.618	1.00
243_E	249_T	0.618	1.00
308_L	312_T	0.617	1.00
292_F	312_T	0.616	1.00
182_A	187_A	0.616	1.00
181_F	186_A	0.615	1.00
410_L	415_L	0.614	1.00
339_D	342_Q	0.613	1.00
437_A	440_D	0.611	1.00
321_T	325_N	0.610	1.00
396_I	405_V	0.609	1.00
192_I	198_W	0.609	1.00
296_V	302_I	0.604	1.00
25_K	222_D	0.602	1.00
25_K	221_I	0.602	1.00
26_M	29_C	0.602	1.00
183_L	189_E	0.602	1.00
393_T	400_D	0.601	1.00
394_A	401_R	0.598	1.00
265_E	272_G	0.596	1.00
228_Q	231_T	0.594	1.00
426_K	429_E	0.594	1.00
192_I	199_G	0.594	1.00
47_V	225_A	0.589	1.00
324_S	327_Q	0.586	1.00
420_I	426_K	0.586	1.00
206_H	211_A	0.586	1.00
205_W	210_S	0.585	1.00
26_M	34_Y	0.585	1.00
279_D	306_E	0.584	1.00
395_F	400_D	0.584	1.00
175_K	180_D	0.584	1.00
19_L	252_K	0.584	1.00
417_D	424_I	0.583	1.00
36_Y	276_L	0.582	0.99
417_D	428_N	0.581	0.99
23_K	63_Q	0.580	0.99
424_I	427_R	0.580	0.99
142_V	151_G	0.579	0.99
178_A	188_K	0.578	0.99
63_Q	111_L	0.577	0.99
189_E	199_G	0.577	0.99
27_Y	32_T	0.576	0.99
262_I	303_N	0.574	0.99
417_D	420_I	0.573	0.99
345_E	414_E	0.573	0.99
209_C	217_L	0.573	0.99
343_W	374_L	0.572	0.99
413_Q	417_D	0.569	0.99
94_I	112_H	0.569	0.99
207_I	211_A	0.569	0.99
398_M	403_V	0.568	0.99
396_I	404_S	0.568	0.99
39_I	267_M	0.567	0.99
147_R	167_A	0.566	0.99
199_G	206_H	0.566	0.99
228_Q	301_P	0.566	0.99
349_E	417_D	0.565	0.99
399_F	403_V	0.564	0.99
79_A	86_V	0.563	0.99
204_G	209_C	0.563	0.99
214_K	219_D	0.561	0.99
206_H	210_S	0.561	0.99
268_S	271_L	0.561	0.99
203_P	206_H	0.560	0.99
175_K	179_L	0.560	0.99
410_L	414_E	0.560	0.99
182_A	188_K	0.557	0.99
132_K	247_G	0.556	0.99
275_V	304_Y	0.556	0.99
304_Y	309_L	0.556	0.99
119_M	123_I	0.556	0.99
206_H	212_M	0.555	0.99
33_V	45_A	0.554	0.99
189_E	197_P	0.553	0.99
111_L	216_Y	0.553	0.99
347_V	398_M	0.552	0.99
191_E	198_W	0.552	0.99
294_L	368_I	0.551	0.99
44_P	48_Y	0.551	0.99
205_W	214_K	0.550	0.99
187_A	190_G	0.549	0.99
311_N	315_A	0.549	0.99
165_S	171_V	0.548	0.99
158_Q	161_D	0.548	0.99
284_H	310_E	0.548	0.99
430_A	435_D	0.546	0.99
325_N	382_L	0.546	0.99
204_G	208_E	0.546	0.99
390_H	405_V	0.545	0.99
416_L	420_I	0.545	0.99
199_G	202_R	0.544	0.99
164_R	167_A	0.544	0.99
366_N	370_V	0.543	0.99
71_V	119_M	0.542	0.99
274_F	277_V	0.542	0.99
185_K	189_E	0.541	0.99
111_L	115_V	0.540	0.99
204_G	210_S	0.540	0.99
56_E	110_D	0.538	0.99
210_S	215_K	0.538	0.99
191_E	199_G	0.537	0.99
327_Q	331_N	0.537	0.99
419_E	422_D	0.537	0.99
161_D	164_R	0.536	0.99
421_E	424_I	0.535	0.99
166_G	171_V	0.533	0.99
30_G	33_V	0.533	0.99
199_G	205_W	0.533	0.99
66_S	112_H	0.532	0.99
341_D	410_L	0.531	0.99
254_W	298_Y	0.530	0.99
436_F	440_D	0.529	0.99
339_D	385_D	0.529	0.99
329_R	333_S	0.528	0.99
434_R	437_A	0.525	0.99
201_G	207_I	0.525	0.99
129_L	135_A	0.525	0.99
189_E	195_D	0.524	0.99
390_H	408_F	0.524	0.99
179_L	186_A	0.524	0.99
200_K	206_H	0.524	0.99
398_M	404_S	0.524	0.99
141_D	173_E	0.523	0.99
77_K	80_N	0.523	0.99
390_H	396_I	0.523	0.99
218_G	221_I	0.522	0.99
187_A	191_E	0.521	0.99
325_N	329_R	0.521	0.99
205_W	209_C	0.520	0.99
390_H	397_E	0.516	0.99
212_M	217_L	0.515	0.99
159_S	164_R	0.514	0.99
391_V	403_V	0.514	0.99
202_R	207_I	0.510	0.99
110_D	116_M	0.508	0.99
24_V	30_G	0.507	0.99
24_V	223_I	0.507	0.99
201_G	204_G	0.507	0.99
120_D	207_I	0.506	0.99
414_E	418_Q	0.506	0.99
208_E	214_K	0.505	0.99
399_F	407_G	0.505	0.99
367_A	370_V	0.505	0.99
206_H	216_Y	0.504	0.99
232_F	236_E	0.503	0.99
356_E	359_D	0.502	0.99
178_A	183_L	0.502	0.99
56_E	62_V	0.502	0.99
186_A	191_E	0.501	0.98
196_S	199_G	0.500	0.98

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3tqoA	1	0.8155	100	0.227	Contact Map
1li5A	1	0.8155	100	0.234	Contact Map
3sp1A	1	0.9056	100	0.261	Contact Map
1gaxA	1	0.9871	100	0.295	Contact Map
1rqgA	2	0.9464	100	0.313	Contact Map
3kflA	1	0.912	100	0.319	Contact Map
3ziuA	1	0.9614	100	0.326	Contact Map
1ffyA	1	0.9807	100	0.337	Contact Map
1ileA	1	0.9785	100	0.345	Contact Map
4py2A	1	0.8948	100	0.348	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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