FOLC - BACSU - GREMLIN Contacts

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FOLC - Folylpolyglutamate synthase

UniProt:	Q05865	Sequences: MFTAYQDARSWIHGRLKFGVKPGLGRMKQLMARLGHPEKKIRAFHVAGTNGKGSTVAFIRSMLQEAGYTVGTFTSPYIITFNERISVNGIPISDEEWTALVNQMKPHVEALDQTEYGQPTEFEIMTACAFLYFAEFHKVDFVIFETGLGGRFDSTNVVEPLLTVITSIGHDHMNILGNTIEEIAGEKAGIIKEGIPIVTAVTQPEALQVIRHEAERHAAPFQSLHDACVIFNEEALPAGEQFSFKTEEKCYEDIRTSLIGTHQRQNAALSILAAEWLNKENIAHISDEALRSGLVKAAWPGRLELVQEHPPVYLDGAHNEEGVEKLAETMKQRFANSRISVVFSALKDKPYQNMIKRLETIAHAIHFASFDFPRASLAKDLYDASEISNKSWSEDPDDVIKFIESKKGSNEIVLITGSLYFISDIRKRLK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	430 (399)
Sequences:	5307 (4140)
Seq/√Len:	207.3

ECOLI - FOLC
BACSU - FOLC
HALSA - FOLCP

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
178_N	182_E	3.960	1.00
82_N	94_D	3.774	1.00
164_V	273_A	3.702	1.00
213_E	217_H	3.392	1.00
46_V	56_V	3.384	1.00
151_R	186_E	3.341	1.00
62_M	274_A	3.162	1.00
191_I	197_I	3.158	1.00
169_G	321_E	3.097	1.00
304_E	426_R	3.047	1.00
96_E	137_H	2.931	1.00
170_H	173_M	2.889	1.00
181_E	205_E	2.745	1.00
162_L	273_A	2.670	1.00
213_E	216_R	2.568	1.00
395_D	398_D	2.564	1.00
179_T	182_E	2.517	1.00
345_A	354_M	2.479	1.00
92_I	132_Y	2.469	1.00
350_P	353_N	2.442	1.00
65_E	296_K	2.305	1.00
103_Q	135_E	2.305	1.00
93_S	96_E	2.267	1.00
301_G	422_I	2.252	1.00
47_A	146_T	2.238	1.00
31_M	157_V	2.230	1.00
49_T	171_D	2.215	1.00
60_R	64_Q	2.214	1.00
316_G	419_L	2.205	1.00
56_V	72_T	2.188	1.00
80_T	91_P	2.150	1.00
63_L	141_F	2.107	1.00
139_V	142_V	2.020	1.00
103_Q	131_L	2.002	1.00
366_H	393_S	1.962	1.00
340_S	366_H	1.954	1.00
80_T	94_D	1.933	1.00
81_F	125_M	1.898	1.00
131_L	135_E	1.880	1.00
305_L	311_P	1.872	1.00
148_L	175_I	1.830	1.00
61_S	293_G	1.824	1.00
40_K	134_A	1.791	1.00
99_A	135_E	1.775	1.00
341_V	362_A	1.727	1.00
65_E	292_S	1.724	1.00
287_D	291_R	1.709	1.00
56_V	143_I	1.692	1.00
208_Q	212_H	1.692	1.00
73_F	126_T	1.689	1.00
29_Q	33_R	1.681	1.00
165_I	191_I	1.681	1.00
43_A	158_V	1.675	1.00
300_P	304_E	1.636	1.00
393_S	402_F	1.633	1.00
41_I	142_V	1.632	1.00
305_L	313_Y	1.627	1.00
96_E	99_A	1.625	1.00
286_S	289_A	1.624	1.00
340_S	364_A	1.619	1.00
170_H	180_I	1.618	1.00
30_L	119_P	1.615	1.00
27_M	127_A	1.612	1.00
323_V	354_M	1.607	1.00
292_S	296_K	1.595	1.00
32_A	36_H	1.590	1.00
162_L	198_V	1.589	1.00
55_T	166_T	1.574	1.00
351_Y	376_S	1.557	1.00
324_E	357_R	1.553	1.00
348_D	374_R	1.548	1.00
69_T	88_N	1.546	1.00
82_N	91_P	1.545	1.00
364_A	391_S	1.533	1.00
222_Q	276_W	1.519	1.00
79_I	423_S	1.509	1.00
193_E	217_H	1.498	1.00
58_F	297_A	1.495	1.00
369_S	378_A	1.490	1.00
326_L	414_L	1.490	1.00
197_I	219_A	1.486	1.00
338_R	411_E	1.483	1.00
130_F	144_F	1.483	1.00
55_T	164_V	1.480	1.00
355_I	385_S	1.475	1.00
144_F	158_V	1.474	1.00
182_E	185_G	1.472	1.00
207_L	223_S	1.462	1.00
62_M	293_G	1.460	1.00
342_V	403_I	1.449	1.00
212_H	216_R	1.441	1.00
312_V	400_I	1.427	1.00
340_S	406_K	1.412	1.00
59_I	143_I	1.410	1.00
59_I	274_A	1.405	1.00
98_T	102_N	1.393	1.00
325_K	328_E	1.392	1.00
303_L	329_T	1.388	1.00
415_I	425_I	1.378	1.00
303_L	313_Y	1.371	1.00
47_A	190_I	1.369	1.00
191_I	219_A	1.367	1.00
377_L	380_D	1.366	1.00
100_L	132_Y	1.363	1.00
200_A	269_L	1.356	1.00
399_V	403_I	1.344	1.00
25_G	28_K	1.340	1.00
50_N	322_G	1.337	1.00
371_D	424_D	1.332	1.00
30_L	127_A	1.329	1.00
58_F	270_S	1.326	1.00
77_Y	84_R	1.318	1.00
352_Q	384_A	1.318	1.00
167_S	321_E	1.317	1.00
382_Y	386_E	1.315	1.00
13_H	121_E	1.310	1.00
57_A	297_A	1.307	1.00
342_V	413_V	1.299	1.00
339_I	412_I	1.296	1.00
396_P	425_I	1.292	1.00
330_M	414_L	1.292	1.00
320_E	353_N	1.287	1.00
60_R	72_T	1.287	1.00
72_T	86_S	1.286	1.00
29_Q	32_A	1.283	1.00
68_Y	140_D	1.280	1.00
81_F	97_W	1.277	1.00
66_A	289_A	1.277	1.00
100_L	131_L	1.274	1.00
185_G	213_E	1.268	1.00
345_A	351_Y	1.247	1.00
79_I	426_R	1.247	1.00
211_R	215_E	1.241	1.00
188_A	213_E	1.238	1.00
261_T	328_E	1.237	1.00
207_L	211_R	1.233	1.00
57_A	299_W	1.232	1.00
194_G	218_A	1.229	1.00
71_G	133_F	1.219	1.00
255_R	295_V	1.218	1.00
199_T	221_F	1.212	1.00
407_K	413_V	1.209	1.00
152_F	186_E	1.209	1.00
163_T	195_I	1.203	1.00
193_E	218_A	1.202	1.00
214_A	221_F	1.201	1.00
342_V	399_V	1.197	1.00
267_A	294_L	1.184	1.00
164_V	269_L	1.179	1.00
39_K	159_E	1.179	1.00
293_G	297_A	1.176	1.00
167_S	202_T	1.173	1.00
77_Y	121_E	1.168	1.00
173_M	178_N	1.168	1.00
78_I	423_S	1.166	1.00
42_R	161_L	1.162	1.00
129_A	144_F	1.156	1.00
45_H	156_N	1.156	1.00
201_V	265_Q	1.154	1.00
196_P	220_P	1.153	1.00
130_F	158_V	1.149	1.00
198_V	269_L	1.146	1.00
60_R	86_S	1.144	1.00
366_H	406_K	1.140	1.00
260_G	263_Q	1.133	1.00
323_V	327_A	1.132	1.00
199_T	207_L	1.128	1.00
331_K	361_I	1.117	1.00
64_Q	88_N	1.117	1.00
159_E	195_I	1.116	1.00
95_E	99_A	1.114	1.00
211_R	223_S	1.112	1.00
261_T	332_Q	1.106	1.00
391_S	402_F	1.105	1.00
59_I	273_A	1.105	1.00
87_V	139_V	1.102	1.00
165_I	210_I	1.098	1.00
69_T	137_H	1.094	1.00
327_A	357_R	1.093	1.00
368_A	399_V	1.092	1.00
63_L	274_A	1.092	1.00
44_F	141_F	1.091	1.00
387_I	390_K	1.090	1.00
366_H	402_F	1.088	1.00
10_S	13_H	1.088	1.00
321_E	324_E	1.083	1.00
339_I	362_A	1.082	1.00
367_F	390_K	1.082	1.00
68_Y	141_F	1.080	1.00
383_D	386_E	1.080	1.00
223_S	226_D	1.072	1.00
92_I	96_E	1.065	1.00
121_E	125_M	1.058	1.00
198_V	276_W	1.055	1.00
141_F	283_A	1.053	1.00
85_I	132_Y	1.050	1.00
378_A	392_W	1.049	1.00
253_D	256_T	1.048	1.00
312_V	404_E	1.047	1.00
340_S	411_E	1.046	1.00
101_V	128_C	1.045	1.00
289_A	293_G	1.042	1.00
254_I	257_S	1.039	1.00
188_A	210_I	1.034	1.00
96_E	132_Y	1.031	1.00
34_L	131_L	1.029	1.00
54_S	263_Q	1.027	1.00
191_I	214_A	1.026	1.00
191_I	210_I	1.021	1.00
314_L	422_I	1.017	1.00
206_A	210_I	1.013	1.00
97_W	128_C	1.009	1.00
344_S	370_F	1.007	1.00
337_S	410_N	1.002	1.00
104_M	107_H	0.999	1.00
59_I	164_V	0.999	1.00
151_R	185_G	0.998	1.00
160_P	192_K	0.997	1.00
341_V	414_L	0.997	1.00
338_R	364_A	0.995	1.00
60_R	143_I	0.995	1.00
402_F	406_K	0.985	1.00
174_N	348_D	0.985	1.00
169_G	324_E	0.984	1.00
403_I	413_V	0.983	1.00
61_S	297_A	0.982	1.00
73_F	154_S	0.977	1.00
370_F	421_F	0.974	1.00
96_E	135_E	0.971	1.00
402_F	405_S	0.971	1.00
208_Q	211_R	0.968	1.00
358_L	416_T	0.963	1.00
44_F	277_L	0.960	1.00
242_F	267_A	0.960	1.00
223_S	227_A	0.953	0.99
132_Y	137_H	0.952	0.99
338_R	363_H	0.950	0.99
86_S	91_P	0.947	0.99
71_G	139_V	0.946	0.99
347_K	380_D	0.941	0.99
262_H	325_K	0.941	0.99
92_I	97_W	0.936	0.99
66_A	285_I	0.934	0.99
59_I	270_S	0.932	0.99
191_I	217_H	0.931	0.99
272_L	275_E	0.926	0.99
185_G	212_H	0.926	0.99
299_W	419_L	0.925	0.99
151_R	213_E	0.925	0.99
66_A	286_S	0.924	0.99
343_F	355_I	0.923	0.99
400_I	425_I	0.922	0.99
36_H	39_K	0.915	0.99
327_A	331_K	0.913	0.99
62_M	294_L	0.911	0.99
87_V	137_H	0.909	0.99
222_Q	272_L	0.904	0.99
198_V	273_A	0.901	0.99
376_S	380_D	0.900	0.99
63_L	143_I	0.896	0.99
263_Q	266_N	0.894	0.99
323_V	357_R	0.893	0.99
380_D	383_D	0.889	0.99
256_T	267_A	0.889	0.99
100_L	128_C	0.888	0.99
181_E	206_A	0.885	0.99
351_Y	384_A	0.879	0.99
367_F	378_A	0.878	0.99
58_F	267_A	0.877	0.99
199_T	223_S	0.875	0.99
173_M	350_P	0.875	0.99
254_I	291_R	0.874	0.99
305_L	308_E	0.874	0.99
288_E	292_S	0.874	0.99
294_L	297_A	0.872	0.99
58_F	257_S	0.871	0.99
20_V	23_G	0.871	0.99
320_E	324_E	0.870	0.99
206_A	209_V	0.868	0.99
258_L	263_Q	0.868	0.99
278_N	287_D	0.867	0.99
50_N	319_N	0.864	0.99
341_V	416_T	0.863	0.99
167_S	200_A	0.862	0.99
311_P	412_I	0.861	0.99
369_S	375_A	0.856	0.99
154_S	186_E	0.854	0.99
323_V	358_L	0.853	0.99
346_L	420_Y	0.851	0.99
100_L	135_E	0.849	0.99
85_I	92_I	0.843	0.99
55_T	270_S	0.840	0.99
204_P	208_Q	0.839	0.99
31_M	127_A	0.835	0.99
336_N	412_I	0.833	0.99
344_S	368_A	0.831	0.99
146_T	190_I	0.831	0.99
394_E	398_D	0.830	0.99
240_E	244_F	0.828	0.99
60_R	89_G	0.826	0.99
160_P	195_I	0.824	0.98
320_E	350_P	0.822	0.98
43_A	142_V	0.821	0.98
164_V	198_V	0.820	0.98
77_Y	83_E	0.819	0.98
313_Y	412_I	0.819	0.98
41_I	139_V	0.818	0.98
271_I	290_L	0.817	0.98
171_D	319_N	0.814	0.98
55_T	269_L	0.808	0.98
165_I	197_I	0.807	0.98
211_R	221_F	0.806	0.98
141_F	161_L	0.805	0.98
61_S	65_E	0.805	0.98
100_L	103_Q	0.803	0.98
258_L	297_A	0.802	0.98
169_G	320_E	0.800	0.98
188_A	191_I	0.799	0.98
156_N	192_K	0.797	0.98
20_V	120_T	0.797	0.98
58_F	294_L	0.796	0.98
251_Y	254_I	0.796	0.98
341_V	365_I	0.795	0.98
312_V	413_V	0.795	0.98
382_Y	392_W	0.793	0.98
65_E	293_G	0.791	0.98
64_Q	89_G	0.789	0.98
160_P	163_T	0.787	0.98
31_M	38_E	0.785	0.98
225_H	228_C	0.782	0.98
290_L	293_G	0.781	0.98
322_G	325_K	0.777	0.98
57_A	61_S	0.777	0.98
424_D	427_K	0.775	0.98
43_A	144_F	0.773	0.98
45_H	192_K	0.767	0.98
251_Y	275_E	0.765	0.98
376_S	384_A	0.764	0.98
20_V	148_L	0.761	0.97
256_T	294_L	0.761	0.97
23_G	27_M	0.759	0.97
20_V	175_I	0.759	0.97
64_Q	70_V	0.758	0.97
72_T	143_I	0.754	0.97
323_V	326_L	0.753	0.97
180_I	205_E	0.753	0.97
317_A	322_G	0.749	0.97
33_R	107_H	0.748	0.97
62_M	290_L	0.746	0.97
324_E	328_E	0.744	0.97
370_F	375_A	0.744	0.97
34_L	104_M	0.743	0.97
342_V	415_I	0.743	0.97
181_E	209_V	0.742	0.97
262_H	303_L	0.741	0.97
97_W	125_M	0.741	0.97
326_L	416_T	0.739	0.97
199_T	210_I	0.738	0.97
367_F	382_Y	0.738	0.97
11_W	15_R	0.737	0.97
346_L	370_F	0.732	0.97
178_N	181_E	0.732	0.97
364_A	389_N	0.730	0.97
393_S	398_D	0.729	0.97
364_A	406_K	0.728	0.97
82_N	97_W	0.725	0.97
336_N	339_I	0.725	0.97
165_I	189_G	0.724	0.97
343_F	416_T	0.724	0.97
15_R	124_I	0.721	0.97
62_M	66_A	0.721	0.97
163_T	197_I	0.720	0.96
366_H	403_I	0.719	0.96
173_M	182_E	0.717	0.96
372_F	420_Y	0.717	0.96
379_K	392_W	0.716	0.96
228_C	268_A	0.716	0.96
245_K	250_C	0.713	0.96
317_A	414_L	0.712	0.96
340_S	407_K	0.712	0.96
285_I	289_A	0.711	0.96
367_F	392_W	0.710	0.96
45_H	155_T	0.708	0.96
120_T	123_E	0.707	0.96
202_T	206_A	0.707	0.96
81_F	85_I	0.706	0.96
369_S	394_E	0.706	0.96
44_F	274_A	0.701	0.96
337_S	412_I	0.697	0.96
199_T	269_L	0.697	0.96
243_S	253_D	0.696	0.96
22_P	26_R	0.694	0.96
122_F	147_G	0.694	0.96
16_L	21_K	0.694	0.96
292_S	295_V	0.691	0.96
307_Q	311_P	0.690	0.96
27_M	154_S	0.688	0.95
287_D	290_L	0.684	0.95
267_A	297_A	0.684	0.95
244_F	272_L	0.683	0.95
212_H	215_E	0.683	0.95
211_R	226_D	0.682	0.95
306_V	314_L	0.680	0.95
352_Q	356_K	0.680	0.95
21_K	26_R	0.675	0.95
45_H	160_P	0.674	0.95
131_L	134_A	0.674	0.95
362_A	414_L	0.674	0.95
59_I	63_L	0.674	0.95
321_E	325_K	0.673	0.95
31_M	37_P	0.670	0.95
81_F	121_E	0.670	0.95
85_I	133_F	0.669	0.95
92_I	100_L	0.668	0.95
47_A	168_I	0.664	0.95
104_M	128_C	0.664	0.95
23_G	26_R	0.663	0.94
369_S	377_L	0.663	0.94
103_Q	107_H	0.663	0.94
10_S	14_G	0.660	0.94
351_Y	381_L	0.660	0.94
26_R	117_G	0.659	0.94
163_T	190_I	0.657	0.94
380_D	384_A	0.657	0.94
87_V	132_Y	0.656	0.94
353_N	357_R	0.655	0.94
164_V	270_S	0.654	0.94
152_F	185_G	0.653	0.94
326_L	330_M	0.647	0.94
337_S	411_E	0.646	0.94
63_L	70_V	0.646	0.94
11_W	105_K	0.645	0.94
162_L	277_L	0.644	0.94
180_I	206_A	0.643	0.94
334_F	412_I	0.642	0.93
62_M	271_I	0.641	0.93
85_I	125_M	0.640	0.93
379_K	383_D	0.640	0.93
401_K	405_S	0.639	0.93
382_Y	390_K	0.639	0.93
73_F	84_R	0.637	0.93
28_K	159_E	0.635	0.93
408_G	411_E	0.634	0.93
181_E	208_Q	0.634	0.93
314_L	415_I	0.634	0.93
421_F	425_I	0.633	0.93
81_F	84_R	0.632	0.93
102_N	105_K	0.630	0.93
244_F	271_I	0.629	0.93
313_Y	329_T	0.627	0.93
29_Q	114_T	0.626	0.93
73_F	129_A	0.625	0.93
403_I	407_K	0.625	0.93
160_P	196_P	0.625	0.93
42_R	141_F	0.623	0.92
307_Q	310_P	0.622	0.92
300_P	426_R	0.620	0.92
362_A	365_I	0.619	0.92
202_T	265_Q	0.618	0.92
129_A	133_F	0.618	0.92
314_L	426_R	0.618	0.92
102_N	106_P	0.617	0.92
312_V	415_I	0.616	0.92
49_T	169_G	0.615	0.92
401_K	404_E	0.614	0.92
38_E	157_V	0.612	0.92
184_A	208_Q	0.611	0.92
156_N	190_I	0.610	0.92
372_F	375_A	0.610	0.92
237_P	240_E	0.609	0.92
34_L	107_H	0.608	0.92
224_L	265_Q	0.606	0.91
342_V	368_A	0.603	0.91
49_T	319_N	0.602	0.91
30_L	124_I	0.602	0.91
379_K	382_Y	0.602	0.91
188_A	209_V	0.601	0.91
262_H	322_G	0.600	0.91
85_I	129_A	0.596	0.91
94_D	97_W	0.594	0.91
46_V	273_A	0.593	0.90
24_L	27_M	0.591	0.90
174_N	347_K	0.591	0.90
77_Y	125_M	0.589	0.90
340_S	413_V	0.589	0.90
306_V	310_P	0.588	0.90
271_I	275_E	0.588	0.90
173_M	183_I	0.586	0.90
203_Q	206_A	0.583	0.90
291_R	295_V	0.582	0.90
368_A	396_P	0.582	0.90
71_G	85_I	0.581	0.90
353_N	356_K	0.580	0.90
225_H	229_V	0.579	0.89
79_I	427_K	0.579	0.89
11_W	14_G	0.578	0.89
397_D	401_K	0.578	0.89
200_A	265_Q	0.577	0.89
202_T	210_I	0.576	0.89
340_S	403_I	0.576	0.89
198_V	222_Q	0.575	0.89
370_F	420_Y	0.575	0.89
224_L	228_C	0.574	0.89
398_D	401_K	0.572	0.89
346_L	376_S	0.571	0.89
367_F	381_L	0.571	0.89
267_A	293_G	0.570	0.89
386_E	390_K	0.569	0.89
339_I	363_H	0.568	0.89
66_A	290_L	0.564	0.88
195_I	220_P	0.564	0.88
173_M	179_T	0.564	0.88
130_F	157_V	0.563	0.88
69_T	87_V	0.562	0.88
307_Q	404_E	0.562	0.88
18_F	21_K	0.559	0.88
367_F	385_S	0.558	0.88
165_I	190_I	0.556	0.87
46_V	146_T	0.554	0.87
189_G	192_K	0.553	0.87
345_A	376_S	0.553	0.87
63_L	68_Y	0.552	0.87
184_A	209_V	0.551	0.87
191_I	213_E	0.550	0.87
346_L	372_F	0.550	0.87
148_L	186_E	0.549	0.87
217_H	220_P	0.548	0.87
163_T	196_P	0.548	0.87
238_A	241_Q	0.546	0.87
378_A	382_Y	0.544	0.86
85_I	97_W	0.544	0.86
60_R	70_V	0.543	0.86
99_A	103_Q	0.542	0.86
182_E	186_E	0.542	0.86
31_M	36_H	0.541	0.86
303_L	326_L	0.541	0.86
27_M	31_M	0.541	0.86
396_P	421_F	0.541	0.86
167_S	201_V	0.538	0.86
368_A	421_F	0.536	0.86
146_T	186_E	0.536	0.86
180_I	203_Q	0.535	0.85
344_S	378_A	0.535	0.85
274_A	278_N	0.535	0.85
41_I	134_A	0.534	0.85
307_Q	312_V	0.533	0.85
27_M	126_T	0.532	0.85
63_L	277_L	0.532	0.85
197_I	221_F	0.532	0.85
84_R	121_E	0.531	0.85
214_A	219_A	0.531	0.85
390_K	393_S	0.530	0.85
78_I	422_I	0.530	0.85
162_L	276_W	0.529	0.85
59_I	62_M	0.529	0.85
146_T	158_V	0.526	0.84
272_L	276_W	0.525	0.84
170_H	182_E	0.524	0.84
165_I	188_A	0.524	0.84
170_H	175_I	0.522	0.84
195_I	219_A	0.521	0.84
311_P	334_F	0.520	0.84
104_M	131_L	0.520	0.84
45_H	163_T	0.520	0.84
61_S	64_Q	0.520	0.84
15_R	18_F	0.520	0.84
184_A	188_A	0.519	0.84
44_F	59_I	0.519	0.84
343_F	367_F	0.518	0.84
354_M	357_R	0.518	0.84
309_H	409_S	0.518	0.84
341_V	358_L	0.518	0.84
56_V	74_T	0.517	0.83
343_F	385_S	0.517	0.83
191_I	209_V	0.516	0.83
241_Q	253_D	0.515	0.83
330_M	339_I	0.515	0.83
73_F	125_M	0.514	0.83
159_E	163_T	0.513	0.83
288_E	291_R	0.512	0.83
199_T	202_T	0.512	0.83
14_G	18_F	0.511	0.83
58_F	258_L	0.511	0.83
126_T	157_V	0.510	0.83
271_I	294_L	0.510	0.83
69_T	140_D	0.509	0.83
393_S	399_V	0.509	0.83
361_I	414_L	0.508	0.82
69_T	139_V	0.508	0.82
146_T	163_T	0.507	0.82
165_I	186_E	0.506	0.82
122_F	126_T	0.506	0.82
229_V	245_K	0.505	0.82
249_K	275_E	0.505	0.82
205_E	208_Q	0.504	0.82
343_F	354_M	0.503	0.82
83_E	423_S	0.501	0.82
317_A	416_T	0.500	0.81

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2vosA	1	0.9814	100	0.226	Contact Map
1jbwA	1	0.9465	100	0.245	Contact Map
1o5zA	1	0.9465	100	0.263	Contact Map
3nrsA	1	0.914	100	0.311	Contact Map
1w78A	1	0.9465	100	0.329	Contact Map
1e8cA	1	0.893	100	0.505	Contact Map
4bubA	1	0.8767	100	0.506	Contact Map
4c12A	2	0.8884	100	0.522	Contact Map
2wtzA	1	0.8953	100	0.524	Contact Map
3zm6A	1	0.8419	100	0.539	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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