GREMLIN Database
YMXH - Uncharacterized protein YmxH
UniProt: Q04811 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 85 (76)
Sequences: 344 (211)
Seq/√Len: 24.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
31_N38_T5.6481.00
65_Q75_D3.7701.00
13_D16_R3.0091.00
40_L60_P2.3490.98
27_D30_I2.3390.98
6_L76_V1.9060.93
13_D18_E1.8920.93
56_D73_I1.8890.92
10_E43_P1.8690.92
39_A50_L1.8510.92
13_D71_M1.7520.89
11_I73_I1.6400.86
10_E22_V1.6200.85
29_E41_L1.6050.85
36_Q47_W1.5170.81
2_R32_E1.3330.72
6_L75_D1.2930.69
47_W56_D1.2820.69
17_A59_V1.2260.65
7_S10_E1.1980.63
62_H77_P1.1230.58
8_G73_I1.1210.58
15_K75_D1.1130.57
11_I32_E1.0820.55
8_G12_V1.0530.53
24_G42_I1.0490.53
48_F54_G1.0420.52
29_E73_I1.0360.52
7_S12_V1.0200.51
19_R43_P1.0190.51
59_V74_L1.0080.50
28_L55_H0.9980.49
16_R59_V0.9940.49
48_F67_I0.9760.48
7_S64_I0.9750.48
19_R24_G0.9670.47
23_L51_R0.9470.46
39_A66_K0.9410.45
29_E32_E0.9360.45
17_A71_M0.9330.45
33_Q47_W0.9300.44
2_R71_M0.9270.44
6_L46_K0.9130.43
14_I73_I0.9090.43
43_P47_W0.9070.43
55_H77_P0.9050.43
42_I47_W0.9010.42
46_K54_G0.8890.42
13_D58_R0.8890.42
7_S24_G0.8760.41
48_F66_K0.8700.40
11_I23_L0.8660.40
40_L74_L0.8650.40
9_K24_G0.8630.40
40_L58_R0.8620.40
20_L74_L0.8600.40
64_I70_D0.8590.39
71_M74_L0.8490.39
3_L10_E0.8330.38
30_I34_D0.8320.38
6_L63_H0.8140.36
28_L54_G0.8120.36
29_E56_D0.8040.36
34_D39_A0.8020.36
63_H75_D0.7870.35
42_I70_D0.7790.34
4_S61_W0.7640.33
40_L64_I0.7550.33
23_L44_T0.7450.32
33_Q72_I0.7410.32
14_I20_L0.7380.32
7_S75_D0.7380.32
29_E70_D0.7320.31
24_G28_L0.7310.31
23_L58_R0.7100.30
2_R34_D0.7080.30
17_A40_L0.6980.29
4_S71_M0.6940.29
45_V70_D0.6940.29
1_M32_E0.6880.29
19_R75_D0.6870.29
57_I78_E0.6790.28
42_I45_V0.6780.28
7_S71_M0.6740.28
36_Q62_H0.6650.27
59_V69_S0.6620.27
5_E12_V0.6610.27
11_I48_F0.6510.26
46_K49_G0.6490.26
29_E58_R0.6400.26
11_I43_P0.6390.26
22_V53_Q0.6190.25
9_K59_V0.6120.24
36_Q50_L0.6070.24
44_T69_S0.6060.24
24_G41_L0.5970.24
1_M43_P0.5900.23
12_V55_H0.5850.23
12_V62_H0.5810.23
15_K19_R0.5790.23
57_I64_I0.5750.22
37_I64_I0.5740.22
69_S72_I0.5670.22
30_I56_D0.5660.22
65_Q78_E0.5560.22
29_E49_G0.5320.20
67_I77_P0.5280.20
7_S51_R0.5210.20
46_K71_M0.5210.20
27_D70_D0.5200.20
39_A48_F0.5190.20
5_E24_G0.5030.19
3_L32_E0.5010.19
2_R69_S0.5000.19
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1pm3A 2 0.8 99.8 0.437 Contact Map
3htrA 2 0.9294 99.4 0.587 Contact Map
1eysH 1 0.8824 95.7 0.814 Contact Map
2wjnH 1 0.8824 93.5 0.835 Contact Map
1rzhH 1 0.8706 91.3 0.845 Contact Map
4da2A 1 0.9176 16.9 0.916 Contact Map
1a62A 1 1 10.7 0.924 Contact Map
3k44A 1 0.4706 6 0.932 Contact Map
2gj2A 3 0.5176 5.7 0.933 Contact Map
4q8wA 2 0.7882 5.3 0.934 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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