MURE - BACSU - GREMLIN Contacts

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MURE - UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase

UniProt:	Q03523	Sequences: MKLTKLLTYLTTEPSVNDSQDPEITSIEMDSREVKKGSLFVCVKGYTVDGHDFAQKAVENGAAAIVAEREVDVNVPVIIVRQSLRALSVLSDAFYGQPTKKLQLIGITGTNGKTSTTHMVDEILKKAGKRTGLIGTMYMKIGDETLPVKNTTPESVTLQKTFKKMNDKHVDTAIMEVSSHALSLGRVHGCDYDIAVFTNLTQDHLDYHKTMDEYRHAKSLLFSQLGGAFNHEHPKRAVLNADDEASAYFEKVTAAHISTYGIKNDADVMAKNISITAQGTSFDLVTNKGTKHITMSLVGQFNVYNVLAAVATCIAAGIPFEIITEAVEELHGVRGRFELVNQQQEFPVIVDYAHTPDSLENVLETCRDMTEGKLFVVVGCGGDRDKTKRPKMAKIAVELADEPIFTSDNPRSEDPRAILRDMEAGVENAYYHSIANREQAIFFAIANAKKGDVVLIAGKGHETYQQIGNETFDFDDAEVAARAIVELNKNKTNS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	494 (399)
Sequences:	16265 (11972)
Seq/√Len:	599.4

ECOLI - MURE MURF MURC MPL MURD
BACSU - MURE MURF MURD MURC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
196_V	312_T	3.462	1.00
260_Y	308_A	2.905	1.00
179_S	182_L	2.698	1.00
376_V	400_A	2.652	1.00
272_N	283_D	2.627	1.00
432_H	443_F	2.535	1.00
196_V	308_A	2.390	1.00
310_V	323_I	2.384	1.00
194_I	312_T	2.372	1.00
103_Q	193_D	2.369	1.00
319_P	322_I	2.365	1.00
402_E	432_H	2.361	1.00
80_V	83_S	2.357	1.00
210_T	213_E	2.333	1.00
434_I	443_F	2.306	1.00
436_N	439_Q	2.275	1.00
126_K	329_E	2.265	1.00
443_F	447_N	2.220	1.00
56_K	60_N	2.187	1.00
271_K	285_V	2.173	1.00
268_V	311_A	2.162	1.00
339_L	347_P	2.155	1.00
402_E	447_N	2.145	1.00
294_T	328_E	2.124	1.00
241_A	266_A	2.122	1.00
123_I	313_C	2.109	1.00
123_I	309_A	2.096	1.00
283_D	292_H	2.094	1.00
58_V	75_V	2.075	1.00
416_R	420_R	2.069	1.00
295_M	306_V	2.064	1.00
41_V	66_V	2.007	1.00
448_A	454_V	2.003	1.00
360_E	364_E	2.001	1.00
382_G	385_D	1.986	1.00
236_R	315_A	1.909	1.00
443_F	446_A	1.898	1.00
126_K	325_E	1.894	1.00
106_G	177_V	1.887	1.00
209_K	213_E	1.878	1.00
126_K	326_A	1.868	1.00
364_E	399_L	1.857	1.00
373_K	452_D	1.854	1.00
215_R	248_Y	1.825	1.00
129_K	171_D	1.825	1.00
106_G	192_Y	1.823	1.00
394_K	398_E	1.800	1.00
193_D	235_K	1.796	1.00
56_K	59_E	1.772	1.00
222_F	237_A	1.763	1.00
404_I	447_N	1.750	1.00
121_D	133_L	1.736	1.00
80_V	84_L	1.715	1.00
122_E	329_E	1.713	1.00
55_Q	59_E	1.710	1.00
120_V	309_A	1.694	1.00
127_A	322_I	1.681	1.00
120_V	312_T	1.680	1.00
270_A	307_L	1.663	1.00
217_A	220_L	1.661	1.00
306_V	327_V	1.641	1.00
105_I	316_A	1.640	1.00
201_T	357_D	1.631	1.00
219_S	252_V	1.629	1.00
375_F	447_N	1.614	1.00
282_F	306_V	1.609	1.00
120_V	313_C	1.609	1.00
262_I	300_Q	1.603	1.00
281_S	292_H	1.593	1.00
339_L	349_I	1.587	1.00
286_T	289_G	1.584	1.00
466_Q	469_N	1.584	1.00
194_I	316_A	1.581	1.00
115_S	302_N	1.571	1.00
269_M	285_V	1.564	1.00
213_E	216_H	1.557	1.00
163_K	167_D	1.556	1.00
111_N	355_T	1.550	1.00
375_F	402_E	1.538	1.00
373_K	402_E	1.537	1.00
404_I	443_F	1.536	1.00
283_D	290_T	1.536	1.00
460_G	465_Q	1.527	1.00
300_Q	364_E	1.517	1.00
384_R	388_K	1.517	1.00
107_I	120_V	1.517	1.00
121_D	125_K	1.516	1.00
417_A	420_R	1.515	1.00
314_I	320_F	1.504	1.00
127_A	318_I	1.499	1.00
241_A	259_T	1.468	1.00
377_V	406_T	1.464	1.00
215_R	245_A	1.462	1.00
285_V	290_T	1.458	1.00
434_I	439_Q	1.453	1.00
195_A	221_L	1.448	1.00
324_T	328_E	1.447	1.00
313_C	323_I	1.444	1.00
419_L	433_S	1.443	1.00
236_R	256_H	1.442	1.00
382_G	461_H	1.441	1.00
270_A	273_I	1.430	1.00
44_K	68_E	1.428	1.00
225_L	235_K	1.407	1.00
346_F	448_A	1.400	1.00
268_V	314_I	1.400	1.00
385_D	388_K	1.397	1.00
348_V	445_I	1.394	1.00
103_Q	172_T	1.391	1.00
119_M	297_L	1.384	1.00
465_Q	469_N	1.383	1.00
281_S	294_T	1.380	1.00
382_G	388_K	1.373	1.00
236_R	258_S	1.369	1.00
122_E	326_A	1.355	1.00
70_E	79_I	1.343	1.00
286_T	314_I	1.339	1.00
48_V	52_D	1.337	1.00
39_L	64_A	1.335	1.00
172_T	316_A	1.322	1.00
274_S	281_S	1.316	1.00
107_I	117_T	1.315	1.00
124_L	316_A	1.310	1.00
364_E	395_I	1.310	1.00
65_I	68_E	1.306	1.00
282_F	303_V	1.300	1.00
296_S	331_H	1.290	1.00
238_V	315_A	1.287	1.00
124_L	174_I	1.283	1.00
105_I	120_V	1.283	1.00
404_I	440_A	1.276	1.00
300_Q	368_D	1.275	1.00
373_K	449_K	1.273	1.00
114_T	333_V	1.271	1.00
104_L	190_C	1.270	1.00
313_C	318_I	1.261	1.00
119_M	330_L	1.260	1.00
437_R	466_Q	1.258	1.00
200_L	215_R	1.256	1.00
342_Q	347_P	1.254	1.00
194_I	315_A	1.253	1.00
202_Q	387_T	1.253	1.00
416_R	433_S	1.250	1.00
68_E	83_S	1.247	1.00
271_K	283_D	1.241	1.00
259_T	267_D	1.239	1.00
258_S	311_A	1.230	1.00
239_L	257_I	1.230	1.00
197_F	200_L	1.228	1.00
375_F	404_I	1.225	1.00
239_L	246_S	1.223	1.00
325_E	329_E	1.220	1.00
360_E	395_I	1.220	1.00
439_Q	442_F	1.217	1.00
361_N	364_E	1.214	1.00
177_V	187_V	1.214	1.00
191_D	235_K	1.204	1.00
103_Q	171_D	1.201	1.00
256_H	315_A	1.195	1.00
359_L	457_A	1.192	1.00
406_T	440_A	1.191	1.00
337_F	349_I	1.190	1.00
442_F	446_A	1.187	1.00
101_K	166_N	1.183	1.00
116_T	198_T	1.182	1.00
322_I	325_E	1.181	1.00
337_F	366_C	1.180	1.00
124_L	172_T	1.172	1.00
89_V	93_A	1.171	1.00
194_I	238_V	1.169	1.00
226_G	234_P	1.166	1.00
240_N	304_Y	1.163	1.00
219_S	249_F	1.158	1.00
382_G	408_D	1.155	1.00
284_L	310_V	1.143	1.00
212_D	216_H	1.142	1.00
239_L	259_T	1.139	1.00
405_F	433_S	1.136	1.00
405_F	419_L	1.128	1.00
402_E	430_Y	1.128	1.00
345_E	450_K	1.120	1.00
97_Q	100_K	1.119	1.00
373_K	401_D	1.118	1.00
245_A	248_Y	1.117	1.00
268_V	286_T	1.115	1.00
54_A	65_I	1.115	1.00
239_L	250_E	1.112	1.00
39_L	66_V	1.105	1.00
291_K	324_T	1.104	1.00
334_R	338_E	1.102	1.00
111_N	357_D	1.100	1.00
216_H	252_V	1.099	1.00
366_C	374_L	1.098	1.00
120_V	196_V	1.097	1.00
197_F	222_F	1.091	1.00
414_D	417_A	1.090	1.00
85_R	89_V	1.071	1.00
90_L	93_A	1.070	1.00
325_E	328_E	1.068	1.00
390_P	421_D	1.066	1.00
132_G	165_M	1.066	1.00
263_K	300_Q	1.060	1.00
130_R	171_D	1.058	1.00
242_D	304_Y	1.056	1.00
318_I	322_I	1.054	1.00
420_R	424_A	1.053	1.00
302_N	305_N	1.046	1.00
321_E	325_E	1.044	1.00
362_V	455_L	1.044	1.00
359_L	378_V	1.044	1.00
262_I	304_Y	1.043	1.00
339_L	342_Q	1.040	1.00
375_F	452_D	1.039	1.00
279_G	294_T	1.037	1.00
458_G	464_Y	1.036	1.00
185_G	217_A	1.035	1.00
248_Y	251_K	1.033	1.00
258_S	315_A	1.033	1.00
438_E	442_F	1.033	1.00
419_L	423_E	1.031	1.00
220_L	223_S	1.031	1.00
198_T	308_A	1.029	1.00
212_D	245_A	1.026	1.00
110_T	203_D	1.021	1.00
391_K	394_K	1.015	1.00
123_I	323_I	1.012	1.00
119_M	306_V	1.007	1.00
416_R	435_A	1.007	1.00
270_A	303_V	1.006	1.00
124_L	318_I	1.004	1.00
179_S	208_H	1.003	1.00
105_I	312_T	1.002	1.00
393_A	422_M	1.002	1.00
261_G	304_Y	1.000	1.00
354_H	359_L	0.999	1.00
420_R	423_E	0.995	1.00
195_A	225_L	0.994	1.00
202_Q	205_L	0.994	1.00
242_D	261_G	0.993	1.00
282_F	293_I	0.992	1.00
185_G	223_S	0.989	1.00
93_A	97_Q	0.989	1.00
312_T	316_A	0.988	1.00
44_K	69_R	0.988	1.00
338_E	350_V	0.986	1.00
211_M	245_A	0.984	1.00
193_D	226_G	0.984	1.00
241_A	247_A	0.982	1.00
57_A	62_A	0.976	1.00
226_G	233_H	0.973	1.00
123_I	326_A	0.968	1.00
108_T	218_K	0.967	1.00
360_E	398_E	0.966	1.00
417_A	421_D	0.964	1.00
262_I	270_A	0.964	1.00
202_Q	211_M	0.958	1.00
122_E	125_K	0.957	1.00
79_I	82_Q	0.953	1.00
185_G	188_H	0.951	1.00
73_V	76_P	0.948	1.00
363_L	399_L	0.945	1.00
390_P	394_K	0.944	1.00
223_S	252_V	0.941	1.00
407_S	435_A	0.939	1.00
423_E	431_Y	0.939	1.00
346_F	451_G	0.938	1.00
89_V	92_D	0.935	1.00
127_A	326_A	0.934	1.00
439_Q	443_F	0.932	1.00
271_K	290_T	0.931	1.00
404_I	434_I	0.928	1.00
48_V	53_F	0.927	1.00
404_I	444_A	0.925	1.00
240_N	243_D	0.924	1.00
444_A	448_A	0.918	1.00
449_K	452_D	0.916	1.00
180_H	207_Y	0.915	1.00
50_G	54_A	0.914	1.00
129_K	172_T	0.911	1.00
357_D	361_N	0.908	1.00
421_D	424_A	0.906	1.00
101_K	163_K	0.906	1.00
45_G	50_G	0.902	1.00
104_L	173_A	0.902	1.00
261_G	264_N	0.901	1.00
88_S	186_R	0.901	1.00
203_D	355_T	0.898	1.00
54_A	58_V	0.898	1.00
213_E	217_A	0.897	1.00
300_Q	304_Y	0.897	1.00
314_I	323_I	0.896	1.00
238_V	311_A	0.893	1.00
197_F	249_F	0.887	1.00
122_E	330_L	0.884	1.00
353_A	457_A	0.882	1.00
276_T	281_S	0.877	1.00
393_A	397_V	0.874	1.00
41_V	87_L	0.874	1.00
216_H	220_L	0.871	1.00
194_I	236_R	0.869	1.00
215_R	219_S	0.869	1.00
349_I	366_C	0.867	1.00
435_A	439_Q	0.866	1.00
41_V	83_S	0.862	1.00
49_D	69_R	0.856	1.00
259_T	266_A	0.851	1.00
293_I	324_T	0.850	1.00
383_D	388_K	0.849	1.00
58_V	65_I	0.848	1.00
335_G	350_V	0.844	1.00
42_C	54_A	0.843	1.00
404_I	432_H	0.838	1.00
376_V	457_A	0.836	1.00
103_Q	316_A	0.835	1.00
40_F	63_A	0.834	1.00
118_H	137_M	0.833	1.00
126_K	322_I	0.833	1.00
415_P	418_I	0.830	1.00
85_R	88_S	0.828	1.00
432_H	447_N	0.826	1.00
423_E	433_S	0.822	1.00
419_L	431_Y	0.821	1.00
342_Q	346_F	0.819	1.00
65_I	75_V	0.815	1.00
422_M	425_G	0.815	1.00
243_D	304_Y	0.809	1.00
244_E	248_Y	0.805	1.00
88_S	92_D	0.804	1.00
395_I	399_L	0.803	1.00
392_M	396_A	0.802	1.00
297_L	330_L	0.802	1.00
418_I	421_D	0.800	1.00
403_P	422_M	0.798	1.00
42_C	67_A	0.796	1.00
225_L	237_A	0.796	1.00
363_L	376_V	0.794	1.00
434_I	440_A	0.789	1.00
67_A	77_V	0.789	1.00
405_F	422_M	0.789	1.00
116_T	309_A	0.785	1.00
201_T	211_M	0.784	1.00
208_H	217_A	0.781	1.00
418_I	422_M	0.781	1.00
247_A	251_K	0.778	1.00
116_T	308_A	0.773	1.00
310_V	314_I	0.772	1.00
51_H	54_A	0.771	1.00
379_G	458_G	0.769	1.00
177_V	192_Y	0.769	1.00
202_Q	357_D	0.761	1.00
372_G	452_D	0.756	1.00
237_A	253_T	0.756	1.00
220_L	224_Q	0.755	1.00
386_K	421_D	0.748	1.00
121_D	131_T	0.746	1.00
276_T	279_G	0.745	1.00
111_N	358_S	0.735	1.00
378_V	422_M	0.734	1.00
347_P	453_V	0.733	1.00
320_F	324_T	0.730	1.00
49_D	52_D	0.730	1.00
396_A	403_P	0.730	1.00
111_N	201_T	0.729	1.00
117_T	133_L	0.727	1.00
241_A	246_S	0.724	1.00
118_H	333_V	0.723	1.00
122_E	126_K	0.722	1.00
275_I	280_T	0.722	1.00
127_A	319_P	0.721	1.00
248_Y	252_V	0.716	1.00
266_A	269_M	0.714	1.00
78_I	82_Q	0.713	1.00
280_T	303_V	0.710	1.00
104_L	175_M	0.710	1.00
84_L	88_S	0.710	1.00
416_R	419_L	0.709	1.00
131_T	170_V	0.709	1.00
92_D	97_Q	0.709	1.00
370_T	453_V	0.707	1.00
247_A	259_T	0.707	1.00
138_Y	145_T	0.707	1.00
219_S	223_S	0.705	1.00
310_V	320_F	0.703	1.00
337_F	365_T	0.701	1.00
212_D	248_Y	0.700	1.00
237_A	255_A	0.694	1.00
291_K	320_F	0.693	1.00
182_L	221_L	0.692	1.00
87_L	90_L	0.691	1.00
392_M	395_I	0.691	1.00
79_I	83_S	0.689	1.00
52_D	69_R	0.689	1.00
240_N	260_Y	0.689	1.00
250_E	259_T	0.688	1.00
297_L	302_N	0.688	1.00
440_A	444_A	0.687	1.00
102_L	166_N	0.683	1.00
191_D	226_G	0.682	1.00
367_R	399_L	0.682	1.00
200_L	211_M	0.681	1.00
377_V	456_I	0.677	1.00
318_I	323_I	0.676	1.00
380_C	462_E	0.675	1.00
241_A	261_G	0.674	1.00
400_A	403_P	0.672	1.00
375_F	448_A	0.671	1.00
335_G	460_G	0.669	1.00
185_G	207_Y	0.665	1.00
405_F	431_Y	0.665	1.00
284_L	307_L	0.663	1.00
185_G	220_L	0.662	1.00
242_D	262_I	0.662	1.00
342_Q	345_E	0.662	1.00
211_M	215_R	0.662	1.00
188_H	224_Q	0.659	1.00
310_V	324_T	0.658	1.00
215_R	249_F	0.657	1.00
51_H	68_E	0.656	1.00
118_H	122_E	0.655	1.00
348_V	454_V	0.655	1.00
44_K	48_V	0.655	1.00
127_A	313_C	0.654	1.00
106_G	221_L	0.653	1.00
323_I	326_A	0.649	1.00
165_M	170_V	0.649	1.00
238_V	312_T	0.648	1.00
51_H	83_S	0.648	1.00
360_E	391_K	0.647	1.00
182_L	217_A	0.647	1.00
353_A	362_V	0.643	1.00
262_I	273_I	0.641	1.00
345_E	451_G	0.641	1.00
58_V	63_A	0.641	1.00
299_G	302_N	0.640	1.00
49_D	53_F	0.638	1.00
82_Q	85_R	0.637	1.00
301_F	361_N	0.636	1.00
289_G	320_F	0.634	1.00
120_V	174_I	0.633	1.00
88_S	93_A	0.633	1.00
401_D	449_K	0.628	1.00
42_C	65_I	0.626	1.00
267_D	287_N	0.625	1.00
377_V	444_A	0.625	1.00
307_L	311_A	0.624	1.00
274_S	292_H	0.624	1.00
233_H	254_A	0.622	1.00
362_V	457_A	0.622	1.00
42_C	51_H	0.621	1.00
303_V	307_L	0.621	1.00
321_E	324_T	0.620	1.00
144_E	168_K	0.619	1.00
406_T	434_I	0.619	1.00
355_T	358_S	0.619	1.00
121_D	132_G	0.618	1.00
131_T	165_M	0.617	1.00
250_E	257_I	0.617	1.00
165_M	173_A	0.614	1.00
91_S	95_Y	0.613	1.00
387_T	390_P	0.613	1.00
389_R	393_A	0.612	1.00
344_Q	450_K	0.611	1.00
405_F	423_E	0.608	1.00
359_L	395_I	0.607	1.00
50_G	53_F	0.607	1.00
43_V	84_L	0.605	1.00
198_T	260_Y	0.605	1.00
293_I	306_V	0.604	1.00
437_R	441_I	0.603	1.00
408_D	414_D	0.603	1.00
205_L	209_K	0.602	1.00
43_V	57_A	0.601	1.00
377_V	454_V	0.600	1.00
366_C	455_L	0.599	1.00
246_S	250_E	0.599	1.00
131_T	174_I	0.599	1.00
107_I	196_V	0.598	1.00
272_N	275_I	0.596	1.00
121_D	174_I	0.596	1.00
197_F	215_R	0.596	1.00
349_I	453_V	0.595	1.00
310_V	327_V	0.595	1.00
118_H	334_R	0.594	1.00
124_L	313_C	0.593	1.00
115_S	330_L	0.593	1.00
375_F	444_A	0.593	1.00
258_S	268_V	0.593	1.00
202_Q	391_K	0.593	1.00
144_E	164_K	0.593	1.00
441_I	445_I	0.592	1.00
88_S	91_S	0.590	1.00
372_G	453_V	0.590	1.00
286_T	320_F	0.589	1.00
282_F	285_V	0.589	1.00
246_S	249_F	0.589	1.00
378_V	405_F	0.589	1.00
247_A	250_E	0.588	1.00
393_A	421_D	0.588	1.00
273_I	282_F	0.587	1.00
395_I	398_E	0.587	1.00
275_I	300_Q	0.586	1.00
253_T	257_I	0.583	1.00
463_T	466_Q	0.583	1.00
407_S	415_P	0.582	1.00
384_R	387_T	0.582	1.00
337_F	362_V	0.581	1.00
356_P	391_K	0.581	1.00
353_A	359_L	0.579	1.00
139_M	142_G	0.577	1.00
273_I	303_V	0.576	1.00
92_D	191_D	0.575	1.00
203_D	218_K	0.573	1.00
105_I	124_L	0.571	1.00
262_I	307_L	0.571	1.00
377_V	440_A	0.570	1.00
388_K	414_D	0.567	1.00
407_S	419_L	0.567	1.00
437_R	464_Y	0.567	1.00
195_A	234_P	0.566	1.00
117_T	174_I	0.564	1.00
205_L	210_T	0.563	1.00
206_D	214_Y	0.563	1.00
406_T	437_R	0.563	1.00
341_N	347_P	0.563	1.00
291_K	321_E	0.562	1.00
85_R	90_L	0.560	1.00
138_Y	142_G	0.560	1.00
216_H	219_S	0.558	1.00
135_G	145_T	0.557	1.00
272_N	292_H	0.557	1.00
132_G	170_V	0.555	0.99
102_L	173_A	0.555	0.99
308_A	312_T	0.555	0.99
438_E	466_Q	0.554	0.99
276_T	294_T	0.553	0.99
123_I	127_A	0.549	0.99
261_G	269_M	0.549	0.99
212_D	215_R	0.549	0.99
186_R	190_C	0.548	0.99
389_R	392_M	0.548	0.99
415_P	419_L	0.545	0.99
87_L	92_D	0.544	0.99
47_T	50_G	0.542	0.99
114_T	137_M	0.542	0.99
264_N	269_M	0.541	0.99
386_K	417_A	0.541	0.99
238_V	258_S	0.540	0.99
118_H	138_Y	0.539	0.99
376_V	396_A	0.538	0.99
94_F	97_Q	0.537	0.99
226_G	235_K	0.535	0.99
376_V	403_P	0.534	0.99
211_M	214_Y	0.531	0.99
45_G	48_V	0.531	0.99
50_G	58_V	0.530	0.99
268_V	287_N	0.530	0.99
394_K	425_G	0.528	0.99
135_G	138_Y	0.528	0.99
40_F	53_F	0.527	0.99
343_Q	346_F	0.525	0.99
246_S	253_T	0.524	0.99
88_S	189_G	0.523	0.99
110_T	201_T	0.522	0.99
265_D	269_M	0.522	0.99
312_T	315_A	0.522	0.99
123_I	318_I	0.521	0.99
300_Q	303_V	0.521	0.99
441_I	456_I	0.520	0.99
54_A	64_A	0.520	0.99
295_M	327_V	0.520	0.99
65_I	77_V	0.519	0.99
359_L	376_V	0.518	0.99
86_A	89_V	0.517	0.99
57_A	61_G	0.517	0.99
44_K	47_T	0.517	0.99
216_H	223_S	0.516	0.99
100_K	191_D	0.515	0.99
187_V	192_Y	0.515	0.99
391_K	395_I	0.514	0.99
344_Q	445_I	0.514	0.99
43_V	47_T	0.513	0.99
55_Q	58_V	0.513	0.99
125_K	130_R	0.512	0.99
107_I	116_T	0.512	0.99
394_K	397_V	0.511	0.99
47_T	52_D	0.509	0.99
181_A	216_H	0.508	0.99
143_D	175_M	0.507	0.99
115_S	119_M	0.506	0.99
415_P	433_S	0.506	0.99
87_L	91_S	0.505	0.99
180_H	206_D	0.505	0.99
322_I	326_A	0.503	0.99
405_F	418_I	0.502	0.99
178_S	181_A	0.501	0.99
367_R	370_T	0.501	0.99
320_F	323_I	0.500	0.99
100_K	103_Q	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4c12A	2	0.9838	100	0.167	Contact Map
4bubA	1	0.9636	100	0.185	Contact Map
2wtzA	1	0.9757	100	0.207	Contact Map
1e8cA	1	0.9717	100	0.218	Contact Map
4qdiA	1	0.8846	100	0.271	Contact Map
4cvkA	1	0.8543	100	0.273	Contact Map
3zm6A	1	0.8826	100	0.284	Contact Map
1gg4A	1	0.8603	100	0.289	Contact Map
3zl8A	1	0.8462	100	0.318	Contact Map
2x5oA	1	0.8441	100	0.41	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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