GREMLIN Database
YWSB - Cell wall-binding protein YwsB
UniProt: P96729 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 178 (139)
Sequences: 187 (178)
Seq/√Len: 15.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
62_K67_S5.4591.00
64_S67_S3.9031.00
73_L79_L2.6460.95
164_G168_Y2.4970.94
52_V57_L2.4210.93
79_L107_I2.1390.87
59_V73_L2.0580.85
152_G156_D2.0220.84
79_L92_V1.9880.83
60_R89_W1.9240.80
154_D157_W1.8380.77
163_G166_T1.8290.77
90_A107_I1.8160.76
59_V92_V1.8160.76
34_E38_S1.8140.76
101_F105_H1.7930.75
157_W161_D1.7060.72
155_F166_T1.6730.70
156_D159_F1.6600.69
153_F156_D1.6450.69
163_G167_G1.6320.68
89_W100_G1.6290.68
159_F164_G1.5720.65
61_T68_Q1.5510.64
55_E63_P1.5220.63
162_Y166_T1.5170.62
138_T141_S1.5160.62
145_W156_D1.5100.62
147_K157_W1.5020.61
106_Y126_A1.4790.60
148_T157_W1.4760.60
91_K99_T1.4670.60
54_A57_L1.4530.59
74_H77_D1.4350.58
156_D162_Y1.4290.57
147_K154_D1.4080.56
164_G167_G1.3950.56
162_Y165_T1.3810.55
102_V106_Y1.3750.54
145_W154_D1.3640.54
146_S154_D1.3320.52
155_F163_G1.3100.51
156_D166_T1.3040.50
145_W149_N1.2980.50
51_L111_A1.2870.50
161_D166_T1.2860.49
57_L106_Y1.2770.49
154_D159_F1.2490.47
155_F167_G1.2450.47
146_S155_F1.2410.47
57_L88_D1.2400.47
146_S153_F1.2370.47
43_Y118_T1.2150.45
64_S86_N1.1960.44
157_W166_T1.1900.44
145_W148_T1.1890.44
29_H32_Q1.1660.43
57_L103_S1.1560.42
148_T152_G1.1500.42
35_T46_P1.1370.41
103_S106_Y1.1340.41
152_G159_F1.1310.41
70_A90_A1.1290.41
155_F159_F1.1280.41
120_T132_K1.1170.40
62_K90_A1.1160.40
120_T124_T1.1070.40
156_D163_G1.1040.39
137_D141_S1.0970.39
154_D167_G1.0830.38
81_L90_A1.0820.38
85_S92_V1.0750.38
162_Y168_Y1.0440.36
49_S78_S1.0400.36
157_W163_G1.0360.36
146_S156_D1.0270.35
146_S149_N1.0150.35
155_F161_D1.0050.34
114_V124_T1.0040.34
61_T99_T0.9860.33
152_G162_Y0.9760.33
147_K150_K0.9740.33
149_N152_G0.9740.33
42_L77_D0.9700.32
85_S91_K0.9520.32
145_W157_W0.9480.31
155_F158_V0.9460.31
52_V58_N0.9400.31
152_G157_W0.9380.31
155_F162_Y0.9170.30
159_F163_G0.9060.29
70_A100_G0.9050.29
28_I33_P0.8960.29
146_S157_W0.8850.28
37_V43_Y0.8820.28
146_S152_G0.8720.28
77_D91_K0.8650.27
90_A104_T0.8630.27
54_A127_D0.8540.27
115_K119_K0.8540.27
156_D167_G0.8510.27
155_F164_G0.8420.26
157_W167_G0.8350.26
148_T156_D0.8290.26
73_L117_K0.8180.25
102_V107_I0.8100.25
47_I81_L0.7970.25
161_D164_G0.7910.24
54_A79_L0.7890.24
153_F157_W0.7880.24
93_K108_V0.7750.24
136_A140_V0.7710.23
137_D142_F0.7700.23
151_G156_D0.7650.23
48_D77_D0.7590.23
71_D92_V0.7470.23
131_I135_P0.7430.22
145_W152_G0.7390.22
152_G163_G0.7360.22
152_G166_T0.7350.22
149_N156_D0.7350.22
153_F158_V0.7290.22
159_F162_Y0.7280.22
62_K65_A0.7280.22
162_Y167_G0.7270.22
154_D158_V0.7230.22
156_D160_V0.7220.22
134_L140_V0.7220.22
159_F166_T0.7210.22
32_Q58_N0.7080.21
131_I140_V0.6970.21
91_K101_F0.6900.20
86_N92_V0.6890.20
149_N155_F0.6880.20
37_V45_Y0.6870.20
37_V136_A0.6850.20
149_N153_F0.6840.20
147_K153_F0.6820.20
77_D94_Y0.6720.20
65_A68_Q0.6700.20
160_V165_T0.6690.20
31_Q81_L0.6660.19
84_F116_T0.6610.19
36_T101_F0.6490.19
60_R100_G0.6430.19
92_V97_G0.6420.19
50_Y54_A0.6400.19
64_S159_F0.6390.19
163_G168_Y0.6380.19
145_W150_K0.6370.18
135_P139_S0.6330.18
147_K151_G0.6330.18
149_N159_F0.6300.18
133_T144_G0.6270.18
81_L107_I0.6200.18
69_K98_K0.6190.18
40_D81_L0.6180.18
133_T136_A0.6150.18
54_A92_V0.6150.18
73_L77_D0.6150.18
73_L115_K0.6130.18
134_L137_D0.6110.18
58_N68_Q0.6110.18
145_W153_F0.6090.18
83_S91_K0.6040.17
63_P89_W0.6030.17
52_V79_L0.6020.17
75_L98_K0.6020.17
39_I64_S0.5970.17
145_W167_G0.5910.17
133_T149_N0.5860.17
69_K166_T0.5820.17
141_S144_G0.5790.17
66_S84_F0.5740.16
69_K86_N0.5730.16
118_T123_Y0.5710.16
72_T163_G0.5700.16
99_T127_D0.5690.16
73_L101_F0.5670.16
71_D77_D0.5620.16
59_V79_L0.5590.16
86_N90_A0.5580.16
112_T129_K0.5560.16
98_K121_K0.5540.16
146_S162_Y0.5520.16
71_D94_Y0.5520.16
56_A72_T0.5500.16
98_K101_F0.5470.16
114_V123_Y0.5470.16
74_H132_K0.5450.16
150_K153_F0.5410.15
101_F160_V0.5390.15
126_A141_S0.5390.15
111_A139_S0.5350.15
155_F165_T0.5330.15
37_V54_A0.5330.15
67_S85_S0.5330.15
72_T94_Y0.5310.15
31_Q74_H0.5300.15
128_G148_T0.5270.15
92_V100_G0.5240.15
72_T114_V0.5240.15
152_G165_T0.5240.15
86_N135_P0.5230.15
160_V164_G0.5190.15
63_P112_T0.5160.15
150_K157_W0.5040.14
83_S104_T0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2kt8A 1 0.4213 99.4 0.636 Contact Map
2kq8A 1 0.3933 99.4 0.639 Contact Map
2krsA 1 0.4101 99.3 0.65 Contact Map
3npfA 2 0.7528 99.1 0.688 Contact Map
3h41A 1 0.9101 99 0.69 Contact Map
4krtA 1 0.5281 98.9 0.707 Contact Map
2hbwA 1 0.7247 98.6 0.736 Contact Map
3m1uA 2 0.9831 98.2 0.765 Contact Map
1v1cA 1 0.3539 92.8 0.86 Contact Map
1ng2A 2 0.7022 90.9 0.867 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.006 seconds.