GREMLIN Database
YWQC - Probable capsular polysaccharide biosynthesis protein YwqC
UniProt: P96715 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 248 (218)
Sequences: 4719 (4025)
Seq/√Len: 272.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
45_E169_V3.9691.00
36_S176_N3.5641.00
15_T18_I3.2411.00
124_D130_A3.1721.00
131_A162_V3.1271.00
131_A135_N2.8831.00
32_G180_A2.8591.00
35_I40_L2.6661.00
28_A180_A2.6051.00
199_D203_K2.5711.00
124_D129_T2.4341.00
33_G37_F2.3291.00
29_T181_F2.2561.00
17_R195_L2.2111.00
6_S9_E2.1951.00
45_E123_R2.1721.00
188_S192_A2.1131.00
106_K124_D2.0831.00
140_V143_D2.0091.00
172_K175_L1.9771.00
122_V134_A1.9691.00
33_G177_I1.9531.00
24_V28_A1.9521.00
84_P158_S1.9391.00
135_N160_A1.8731.00
127_A134_A1.8661.00
49_Q158_S1.8171.00
180_A184_G1.8071.00
88_D92_K1.7961.00
134_A138_A1.7831.00
136_T140_V1.7821.00
45_E121_S1.7821.00
28_A32_G1.7761.00
21_I25_T1.7681.00
122_V133_I1.7641.00
43_I123_R1.7111.00
29_T177_I1.6871.00
128_E132_H1.6681.00
93_E136_T1.6351.00
123_R170_S1.6131.00
129_T132_H1.6091.00
84_P161_E1.5881.00
36_S177_I1.5411.00
87_L103_L1.5281.00
91_I96_L1.5121.00
21_I192_A1.5081.00
13_T196_E1.4891.00
28_A184_G1.4831.00
134_A160_A1.4521.00
18_I22_M1.4091.00
41_T125_E1.4041.00
25_T185_L1.3901.00
17_R192_A1.3851.00
36_S180_A1.3711.00
37_F173_P1.3701.00
25_T29_T1.3451.00
107_I122_V1.3371.00
43_I170_S1.3371.00
106_K122_V1.3281.00
87_L104_N1.3261.00
48_T138_A1.3161.00
34_L39_A1.3111.00
78_N82_K1.2951.00
46_N163_S1.2851.00
25_T188_S1.2751.00
204_S207_Q1.2721.00
47_S119_N1.2641.00
191_L195_L1.2591.00
24_V188_S1.2571.00
127_A130_A1.2411.00
163_S169_V1.2401.00
64_F68_Q1.2361.00
123_R169_V1.2301.00
184_G188_S1.2231.00
73_L77_Y1.2201.00
126_N129_T1.2161.00
122_V137_I1.2141.00
35_I39_A1.2031.00
85_A158_S1.1931.00
79_V82_K1.1771.00
46_N160_A1.1751.00
15_T19_L1.1531.00
117_V157_L1.1481.00
25_T28_A1.1331.00
87_L137_I1.1291.00
32_G176_N1.1201.00
36_S40_L1.1151.00
89_E140_V1.1091.00
93_E140_V1.1031.00
36_S173_P1.1011.00
112_E115_S1.0981.00
17_R196_E1.0931.00
49_Q119_N1.0851.00
31_A35_I1.0811.00
16_K196_E1.0801.00
49_Q117_V1.0791.00
8_K12_S1.0791.00
20_L195_L1.0781.00
144_K147_S1.0691.00
89_E93_E1.0671.00
76_T116_Q1.0631.00
84_P104_N1.0591.00
170_S173_P1.0551.00
27_A31_A1.0521.00
25_T181_F1.0501.00
32_G184_G1.0481.00
102_E106_K1.0421.00
5_T10_I1.0421.00
120_I134_A1.0371.00
13_T193_F1.0181.00
51_L76_T1.0101.00
40_L43_I1.0051.00
43_I125_E0.9951.00
131_A160_A0.9941.00
164_E167_S0.9911.00
28_A187_G0.9841.00
43_I169_V0.9771.00
173_P177_I0.9751.00
205_E219_T0.9751.00
110_S119_N0.9741.00
17_R20_L0.9691.00
182_A186_A0.9681.00
89_E92_K0.9641.00
132_H136_T0.9611.00
136_T139_S0.9601.00
59_R62_V0.9601.00
183_A190_G0.9571.00
20_L24_V0.9571.00
205_E209_E0.9551.00
88_D100_S0.9421.00
193_F197_H0.9391.00
128_E131_A0.9371.00
13_T192_A0.9351.00
23_I30_A0.9301.00
146_T152_D0.9201.00
130_A134_A0.9161.00
163_S168_P0.9141.00
81_I86_I0.9091.00
168_P173_P0.9081.00
86_I140_V0.8971.00
14_L193_F0.8971.00
84_P88_D0.8951.00
83_S158_S0.8941.00
107_I137_I0.8911.00
47_S121_S0.8881.00
202_I211_L0.8831.00
130_A133_I0.8821.00
90_V137_I0.8811.00
131_A134_A0.8801.00
48_T156_I0.8751.00
170_S176_N0.8751.00
139_S142_Q0.8721.00
175_L179_I0.8621.00
173_P176_N0.8621.00
142_Q145_I0.8571.00
148_I153_N0.8561.00
32_G36_S0.8521.00
207_Q210_S0.8481.00
88_D161_E0.8471.00
48_T134_A0.8451.00
120_I138_A0.8310.99
194_L198_L0.8250.99
21_I188_S0.8240.99
176_N179_I0.8240.99
91_I103_L0.8220.99
205_E216_V0.8170.99
178_A186_A0.8160.99
138_A142_Q0.8120.99
98_M102_E0.8100.99
85_A159_K0.8090.99
127_A163_S0.8080.99
37_F177_I0.8060.99
216_V219_T0.8060.99
81_I120_I0.8020.99
42_P168_P0.8020.99
90_V94_M0.8000.99
13_T17_R0.7930.99
77_Y80_I0.7910.99
145_I148_I0.7900.99
46_N131_A0.7850.99
149_M152_D0.7830.99
17_R199_D0.7730.99
80_I157_L0.7620.99
50_I120_I0.7610.99
49_Q79_V0.7600.99
75_N111_S0.7510.99
6_S10_I0.7440.99
91_I100_S0.7390.99
63_Q66_D0.7370.99
80_I83_S0.7310.99
127_A131_A0.7310.99
171_P176_N0.7310.99
222_T225_N0.7300.99
42_P173_P0.7290.99
195_L199_D0.7280.99
40_L170_S0.7240.99
77_Y141_F0.7230.99
90_V133_I0.7220.99
35_I176_N0.7180.99
110_S121_S0.7170.99
20_L192_A0.7150.98
149_M153_N0.7140.98
21_I189_I0.7140.98
108_T123_R0.7120.98
138_A156_I0.7060.98
46_N162_V0.7060.98
11_L15_T0.7050.98
99_T102_E0.7050.98
103_L122_V0.7040.98
79_V117_V0.7030.98
79_V112_E0.7030.98
139_S143_D0.7000.98
20_L191_L0.6970.98
220_V223_I0.6920.98
29_T180_A0.6890.98
22_M26_A0.6870.98
24_V191_L0.6870.98
190_G194_L0.6860.98
74_I77_Y0.6730.98
83_S157_L0.6700.98
48_T160_A0.6680.98
66_D69_T0.6670.98
36_S39_A0.6650.98
50_I138_A0.6630.98
182_A190_G0.6610.97
98_M106_K0.6590.97
139_S159_K0.6550.97
81_I138_A0.6500.97
14_L189_I0.6490.97
182_A189_I0.6450.97
144_K148_I0.6440.97
50_I81_I0.6440.97
174_L177_I0.6420.97
29_T36_S0.6420.97
127_A133_I0.6410.97
211_L214_I0.6390.97
46_N130_A0.6360.97
51_L54_Q0.6350.97
76_T115_S0.6330.97
77_Y154_V0.6300.97
128_E162_V0.6300.97
189_I192_A0.6280.97
163_S167_S0.6260.97
10_I13_T0.6230.96
45_E164_E0.6200.96
22_M25_T0.6190.96
100_S104_N0.6180.96
74_I78_N0.6180.96
51_L77_Y0.6170.96
134_A140_V0.6160.96
137_I140_V0.6130.96
85_A89_E0.6120.96
112_E119_N0.6110.96
54_Q70_N0.6110.96
81_I141_F0.6060.96
7_L11_L0.6010.96
213_D216_V0.6010.96
182_A185_L0.6000.96
75_N78_N0.5960.95
19_L30_A0.5940.95
9_E210_S0.5920.95
174_L178_A0.5920.95
175_L178_A0.5920.95
202_I207_Q0.5900.95
156_I160_A0.5860.95
60_K63_Q0.5820.95
59_R63_Q0.5820.95
8_K198_L0.5810.95
19_L23_I0.5790.95
8_K17_R0.5770.95
87_L100_S0.5750.94
206_E209_E0.5740.94
96_L100_S0.5720.94
61_E66_D0.5640.94
185_L188_S0.5630.94
141_F145_I0.5580.94
129_T133_I0.5550.93
120_I124_D0.5540.93
20_L31_A0.5510.93
77_Y86_I0.5510.93
146_T149_M0.5500.93
94_M133_I0.5480.93
29_T184_G0.5440.93
135_N159_K0.5440.93
207_Q211_L0.5420.93
85_A88_D0.5410.92
131_A163_S0.5410.92
72_Q75_N0.5390.92
47_S84_P0.5370.92
29_T33_G0.5350.92
65_N68_Q0.5350.92
181_F184_G0.5350.92
73_L76_T0.5340.92
94_M136_T0.5340.92
16_K19_L0.5330.92
167_S174_L0.5320.92
102_E105_D0.5310.92
91_I94_M0.5290.92
30_A34_L0.5290.92
70_N73_L0.5290.92
206_E210_S0.5290.92
105_D109_V0.5280.92
181_F188_S0.5270.91
209_E213_D0.5260.91
103_L107_I0.5260.91
138_A160_A0.5260.91
40_L171_P0.5250.91
52_V154_V0.5240.91
90_V140_V0.5240.91
197_H200_N0.5230.91
129_T134_A0.5220.91
31_A34_L0.5190.91
115_S118_V0.5160.91
18_I30_A0.5140.90
200_N205_E0.5130.90
40_L176_N0.5130.90
124_D133_I0.5120.90
79_V115_S0.5100.90
68_Q72_Q0.5090.90
45_E163_S0.5080.90
20_L23_I0.5080.90
210_S214_I0.5060.90
146_T153_N0.5050.90
21_I28_A0.5040.90
147_S151_V0.5040.90
68_Q71_L0.5030.89
141_F144_K0.5000.89
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4wl1A 3 0.504 100 0.472 Contact Map
3cioA 2 0.1774 95.9 0.871 Contact Map
3la6A 4 0.1774 94.3 0.883 Contact Map
4jlvA 1 0.1613 93 0.889 Contact Map
4jmpA 1 0.1411 92.5 0.891 Contact Map
4jimA 3 0.2379 40.5 0.931 Contact Map
3b8mA 3 0.6694 24.3 0.939 Contact Map
3b8oA 3 0.5847 20 0.941 Contact Map
2ww9B 1 0.2419 17.4 0.943 Contact Map
4w252 1 0.25 15.6 0.944 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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