GREMLIN Database
YDGF - Uncharacterized transporter YdgF
UniProt: P96704 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 458 (420)
Sequences: 24746 (15965)
Seq/√Len: 779.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
143_L347_A4.3521.00
329_S341_N4.2791.00
389_K393_T3.4431.00
381_G416_L3.2261.00
60_G252_L3.2081.00
332_K341_N3.0751.00
238_K242_K2.9781.00
20_K234_E2.8401.00
233_T239_V2.7231.00
84_V323_D2.7221.00
235_N238_K2.6331.00
100_G320_L2.5941.00
136_L351_L2.5691.00
321_A331_A2.5661.00
25_Q246_N2.5391.00
334_T340_R2.4751.00
329_S332_K2.4461.00
439_T443_F2.4031.00
21_N246_N2.3451.00
289_G293_I2.3051.00
231_G322_K2.3051.00
175_G261_V2.2571.00
384_V415_I2.2001.00
280_Q283_V2.1631.00
344_F348_I2.1531.00
88_Q96_A2.1461.00
232_E315_R2.1191.00
72_E391_R2.1151.00
144_I148_A2.1101.00
318_Y322_K2.1081.00
443_F446_L2.0761.00
140_I351_L2.0661.00
21_N239_V2.0641.00
173_V177_V2.0461.00
24_I233_T2.0411.00
21_N25_Q2.0361.00
151_K155_E2.0201.00
143_L343_L2.0161.00
413_Y417_A2.0101.00
147_L340_R1.9721.00
242_K246_N1.9701.00
270_I284_A1.9491.00
135_G354_V1.9291.00
162_L166_I1.9291.00
433_R436_L1.9081.00
447_I451_K1.9071.00
20_K23_H1.9011.00
69_S384_V1.8961.00
25_Q250_R1.8961.00
15_L333_L1.8911.00
104_W346_S1.8831.00
136_L354_V1.8801.00
324_H328_E1.8781.00
385_I416_L1.8751.00
88_Q93_D1.8671.00
443_F447_I1.8491.00
44_S52_I1.8471.00
330_M345_F1.8221.00
91_L389_K1.8161.00
61_I65_L1.8051.00
91_L385_I1.8041.00
267_P270_I1.7881.00
445_L449_I1.7391.00
280_Q284_A1.7351.00
410_F414_L1.7341.00
87_V99_T1.7231.00
417_A421_F1.7131.00
23_H158_F1.7061.00
245_N249_V1.7001.00
19_L23_H1.6881.00
334_T338_V1.6871.00
140_I347_A1.6661.00
62_I418_F1.6621.00
235_N239_V1.6571.00
51_S209_F1.6551.00
436_L443_F1.6551.00
55_A212_S1.6371.00
92_G95_A1.6351.00
139_L350_I1.6201.00
28_A247_I1.6141.00
146_N307_N1.6071.00
336_R340_R1.5851.00
147_L344_F1.5831.00
433_R447_I1.5731.00
99_T382_I1.5651.00
115_L306_C1.5591.00
437_F441_V1.5441.00
122_T134_P1.5271.00
111_A350_I1.5231.00
166_I170_A1.5191.00
444_I448_V1.5081.00
249_V253_L1.5011.00
436_L439_T1.4711.00
283_V291_A1.4641.00
65_L414_L1.4611.00
317_V342_A1.4391.00
389_K392_K1.4321.00
148_A336_R1.4281.00
229_T311_F1.4271.00
318_Y333_L1.4141.00
274_S280_Q1.4141.00
167_A297_V1.4101.00
115_L139_L1.3911.00
118_V299_L1.3851.00
67_M248_P1.3821.00
15_L318_Y1.3811.00
235_N242_K1.3791.00
87_V382_I1.3791.00
341_N345_F1.3761.00
328_E331_A1.3701.00
395_P398_A1.3701.00
61_I414_L1.3691.00
136_L140_I1.3641.00
91_L95_A1.3641.00
313_T346_S1.3631.00
59_T216_V1.3631.00
441_V445_L1.3491.00
328_E332_K1.3441.00
16_Q337_K1.3421.00
80_Y231_G1.3371.00
143_L344_F1.3351.00
139_L347_A1.3281.00
446_L449_I1.3271.00
165_V169_L1.3261.00
398_A401_N1.3191.00
440_P444_I1.3141.00
432_T436_L1.2991.00
67_M244_I1.2991.00
332_K340_R1.2971.00
23_H154_G1.2971.00
118_V138_A1.2951.00
314_S343_L1.2931.00
385_I389_K1.2891.00
77_N89_D1.2781.00
236_P241_P1.2781.00
394_R397_L1.2731.00
19_L24_I1.2721.00
434_V437_F1.2671.00
90_Y386_C1.2641.00
292_S296_F1.2621.00
66_I384_V1.2481.00
407_L411_T1.2471.00
21_N242_K1.2411.00
85_D89_D1.2381.00
438_V441_V1.2371.00
94_M450_Y1.2361.00
19_L154_G1.2341.00
177_V182_G1.2311.00
421_F425_V1.2311.00
239_V242_K1.2311.00
439_T442_W1.2301.00
432_T439_T1.2261.00
39_L117_A1.2241.00
68_R245_N1.2161.00
431_D434_V1.2161.00
176_L261_V1.2151.00
69_S412_N1.2091.00
253_L257_G1.2081.00
142_L306_C1.2061.00
381_G420_A1.2011.00
395_P401_N1.2011.00
388_M413_Y1.1961.00
32_A251_V1.1961.00
51_S202_F1.1941.00
283_V288_V1.1881.00
276_S280_Q1.1871.00
53_L260_L1.1851.00
22_R26_L1.1831.00
132_W136_L1.1701.00
446_L450_Y1.1671.00
128_G131_Q1.1601.00
397_L401_N1.1581.00
317_V326_A1.1471.00
179_I264_S1.1391.00
172_I257_G1.1361.00
28_A226_V1.1311.00
24_I243_A1.1231.00
176_L180_F1.1201.00
432_T435_S1.1171.00
145_M156_L1.1151.00
180_F183_F1.1101.00
114_D305_A1.1091.00
104_W317_V1.1071.00
76_S401_N1.0981.00
70_L83_F1.0931.00
234_E239_V1.0901.00
97_F101_W1.0871.00
156_L160_F1.0871.00
27_I229_T1.0761.00
442_W446_L1.0751.00
79_N85_D1.0741.00
130_P133_V1.0711.00
407_L410_F1.0701.00
341_N344_F1.0681.00
433_R439_T1.0681.00
431_D435_S1.0681.00
438_V442_W1.0621.00
387_H412_N1.0611.00
431_D436_L1.0571.00
409_P413_Y1.0561.00
441_V444_I1.0551.00
434_V438_V1.0551.00
439_T446_L1.0481.00
392_K395_P1.0471.00
89_D394_R1.0431.00
157_E307_N1.0421.00
181_K184_S1.0391.00
410_F413_Y1.0381.00
45_I52_I1.0371.00
18_G234_E1.0351.00
87_V95_A1.0341.00
133_V137_I1.0341.00
408_Y412_N1.0281.00
436_L444_I1.0281.00
74_L86_F1.0241.00
155_E159_W1.0241.00
392_K409_P1.0221.00
333_L337_K1.0181.00
29_I250_R1.0181.00
197_S200_G1.0161.00
437_F446_L1.0151.00
322_K331_A1.0141.00
137_I141_I1.0131.00
84_V319_S1.0021.00
72_E75_L1.0001.00
416_L420_A0.9981.00
122_T126_L0.9951.00
433_R446_L0.9901.00
119_G134_P0.9871.00
57_M256_I0.9841.00
420_A424_V0.9801.00
348_I352_I0.9801.00
143_L147_L0.9781.00
177_V180_F0.9761.00
433_R437_F0.9731.00
129_V133_V0.9691.00
150_V311_F0.9681.00
448_V451_K0.9651.00
200_G203_P0.9641.00
29_I251_V0.9611.00
268_W271_I0.9581.00
230_A240_I0.9581.00
175_G265_I0.9561.00
436_L440_P0.9541.00
169_L173_V0.9541.00
210_I421_F0.9511.00
170_A174_I0.9491.00
79_N89_D0.9441.00
147_L338_V0.9421.00
381_G419_L0.9381.00
199_G202_F0.9291.00
267_P284_A0.9251.00
140_I144_I0.9241.00
287_I290_A0.9221.00
171_L175_G0.9221.00
224_E228_L0.9201.00
202_F209_F0.9191.00
447_I450_Y0.9171.00
141_I303_A0.9171.00
441_V446_L0.9171.00
26_L158_F0.9161.00
180_F184_S0.9161.00
434_V443_F0.9131.00
286_G290_A0.9101.00
160_F304_S0.9081.00
165_V254_F0.9071.00
384_V416_L0.9071.00
76_S397_L0.9061.00
53_L263_M0.9051.00
381_G385_I0.8961.00
424_V428_L0.8921.00
439_T447_I0.8911.00
182_G185_T0.8901.00
103_Y107_W0.8881.00
81_H85_D0.8831.00
142_L307_N0.8821.00
437_F440_P0.8821.00
65_L411_T0.8811.00
164_K301_S0.8801.00
205_G208_G0.8781.00
310_V347_A0.8751.00
179_I183_F0.8731.00
221_V376_F0.8711.00
198_H201_L0.8691.00
246_N250_R0.8661.00
177_V181_K0.8651.00
442_W445_L0.8611.00
92_G451_K0.8611.00
434_V447_I0.8571.00
22_R158_F0.8561.00
435_S439_T0.8551.00
147_L334_T0.8541.00
172_I176_L0.8541.00
415_I419_L0.8541.00
198_H202_F0.8521.00
134_P137_I0.8491.00
172_I261_V0.8481.00
122_T299_L0.8471.00
274_S277_P0.8461.00
179_I182_G0.8451.00
18_G151_K0.8441.00
33_I36_G0.8441.00
252_L256_I0.8431.00
23_H155_E0.8421.00
171_L282_F0.8391.00
340_R344_F0.8391.00
88_Q323_D0.8381.00
330_M341_N0.8381.00
440_P443_F0.8361.00
436_L446_L0.8361.00
433_R444_I0.8341.00
436_L441_V0.8341.00
199_G203_P0.8321.00
391_R395_P0.8261.00
113_A218_F0.8241.00
421_F424_V0.8231.00
437_F443_F0.8221.00
75_L402_K0.8211.00
437_F444_I0.8201.00
60_G220_F0.8171.00
81_H84_V0.8171.00
101_W326_A0.8171.00
396_E401_N0.8151.00
15_L232_E0.8111.00
206_M209_F0.8081.00
347_A351_L0.8081.00
211_L215_M0.8081.00
436_L447_I0.8071.00
15_L315_R0.8061.00
277_P282_F0.8031.00
433_R440_P0.8031.00
123_Q127_P0.8031.00
288_V292_S0.7991.00
334_T337_K0.7941.00
64_F68_R0.7931.00
437_F445_L0.7901.00
113_A369_T0.7901.00
432_T443_F0.7891.00
272_N277_P0.7881.00
433_R450_Y0.7881.00
155_E158_F0.7861.00
94_M98_I0.7851.00
54_F209_F0.7851.00
388_M392_K0.7851.00
132_W354_V0.7821.00
282_F285_V0.7781.00
57_M61_I0.7751.00
118_V303_A0.7741.00
260_L264_S0.7741.00
92_G96_A0.7731.00
21_N243_A0.7731.00
436_L450_Y0.7721.00
119_G135_G0.7721.00
435_S448_V0.7701.00
326_A330_M0.7681.00
139_L354_V0.7651.00
423_L426_L0.7631.00
371_I375_C0.7621.00
64_F245_N0.7621.00
440_P447_I0.7621.00
434_V439_T0.7611.00
433_R448_V0.7611.00
437_F448_V0.7611.00
225_L312_S0.7601.00
66_I419_L0.7571.00
179_I184_S0.7561.00
419_L422_V0.7541.00
434_V446_L0.7531.00
265_I281_V0.7471.00
431_D447_I0.7461.00
33_I164_K0.7431.00
118_V302_A0.7421.00
221_V380_W0.7421.00
101_W443_F0.7421.00
65_L69_S0.7391.00
116_T368_I0.7381.00
87_V386_C0.7371.00
95_A382_I0.7291.00
144_I147_L0.7291.00
73_L86_F0.7281.00
148_A152_L0.7261.00
18_G150_V0.7261.00
433_R443_F0.7171.00
438_V443_F0.7171.00
388_M412_N0.7161.00
196_W199_G0.7161.00
18_G22_R0.7161.00
132_W135_G0.7151.00
197_S201_L0.7141.00
433_R442_W0.7131.00
73_L387_H0.7121.00
25_Q243_A0.7091.00
273_P277_P0.7071.00
408_Y411_T0.7051.00
147_L336_R0.7031.00
142_L310_V0.7001.00
112_M115_L0.7001.00
277_P281_V0.6971.00
32_A247_I0.6961.00
348_I351_L0.6951.00
68_R411_T0.6941.00
435_S438_V0.6941.00
235_N241_P0.6931.00
44_S48_A0.6921.00
33_I38_F0.6891.00
192_F196_W0.6891.00
409_P412_N0.6801.00
405_L408_Y0.6801.00
197_S202_F0.6791.00
175_G179_I0.6791.00
34_G38_F0.6771.00
443_F450_Y0.6761.00
54_F58_I0.6751.00
387_H391_R0.6731.00
54_F57_M0.6711.00
63_C223_I0.6701.00
119_G122_T0.6691.00
241_P244_I0.6681.00
431_D437_F0.6681.00
439_T450_Y0.6661.00
439_T444_I0.6661.00
276_S279_V0.6641.00
154_G158_F0.6641.00
431_D443_F0.6641.00
433_R438_V0.6641.00
432_T437_F0.6631.00
84_V88_Q0.6631.00
76_S402_K0.6601.00
15_L18_G0.6601.00
330_M342_A0.6601.00
142_L303_A0.6601.00
374_V423_L0.6571.00
181_K185_T0.6571.00
37_L258_A0.6561.00
257_G261_V0.6561.00
315_R318_Y0.6561.00
415_I418_F0.6551.00
30_G161_A0.6551.00
22_R155_E0.6541.00
108_I349_V0.6541.00
146_N343_L0.6541.00
136_L355_T0.6521.00
317_V345_F0.6521.00
434_V444_I0.6511.00
422_V426_L0.6511.00
329_S345_F0.6451.00
176_L257_G0.6441.00
412_N416_L0.6441.00
440_P446_L0.6441.00
196_W201_L0.6441.00
431_D446_L0.6431.00
70_L383_T0.6421.00
314_S342_A0.6411.00
112_M368_I0.6401.00
122_T138_A0.6401.00
118_V122_T0.6391.00
106_C376_F0.6381.00
147_L343_L0.6361.00
68_R406_P0.6351.00
50_P263_M0.6351.00
196_W200_G0.6351.00
435_S442_W0.6351.00
179_I261_V0.6301.00
41_S259_L0.6291.00
90_Y390_Y0.6281.00
310_V314_S0.6281.00
250_R254_F0.6271.00
335_Q340_R0.6271.00
152_L155_E0.6251.00
232_E339_P0.6251.00
246_N249_V0.6221.00
178_M181_K0.6181.00
146_N311_F0.6181.00
405_L411_T0.6151.00
84_V100_G0.6111.00
442_W447_I0.6111.00
121_Y298_V0.6101.00
339_P342_A0.6101.00
202_F205_G0.6061.00
231_G318_Y0.6051.00
240_I244_I0.6011.00
201_L204_N0.6001.00
163_I297_V0.6001.00
56_Y219_A0.6001.00
31_G308_S0.6001.00
236_P239_V0.5991.00
289_G292_S0.5991.00
125_W296_F0.5981.00
69_S415_I0.5971.00
139_L351_L0.5971.00
40_G369_T0.5971.00
67_M223_I0.5961.00
140_I143_L0.5951.00
80_Y318_Y0.5951.00
31_G309_A0.5941.00
413_Y416_L0.5941.00
444_I447_I0.5941.00
392_K396_E0.5941.00
110_I372_S0.5941.00
71_G75_L0.5921.00
394_R401_N0.5921.00
52_I259_L0.5911.00
313_T317_V0.5901.00
208_G211_L0.5901.00
114_D117_A0.5881.00
150_V229_T0.5881.00
321_A330_M0.5881.00
83_F224_E0.5851.00
74_L240_I0.5831.00
221_V224_E0.5831.00
172_I258_A0.5831.00
237_E402_K0.5821.00
110_I113_A0.5821.00
109_S371_I0.5811.00
388_M409_P0.5801.00
65_L415_I0.5801.00
124_Y295_N0.5791.00
296_F300_T0.5781.00
91_L386_C0.5771.00
53_L57_M0.5771.00
278_F282_F0.5761.00
210_I425_V0.5751.00
22_R25_Q0.5751.00
435_S443_F0.5751.00
192_F264_S0.5731.00
58_I213_F0.5691.00
258_A262_I0.5691.00
250_R253_L0.5681.00
391_R408_Y0.5681.00
375_C379_I0.5671.00
390_Y394_R0.5671.00
406_P410_F0.5661.00
110_I114_D0.5661.00
233_T240_I0.5651.00
227_G244_I0.5651.00
72_E406_P0.5651.00
197_S203_P0.5651.00
102_T379_I0.5641.00
149_T152_L0.5641.00
301_S304_S0.5631.00
84_V96_A0.5631.00
115_L119_G0.5621.00
397_L402_K0.5621.00
107_W309_A0.5611.00
74_L227_G0.5611.00
125_W295_N0.5601.00
386_C390_Y0.5591.00
73_L90_Y0.5581.00
59_T217_V0.5561.00
432_T446_L0.5551.00
401_N404_K0.5551.00
436_L442_W0.5541.00
442_W449_I0.5521.00
154_G307_N0.5501.00
432_T450_Y0.5501.00
272_N276_S0.5491.00
153_F311_F0.5491.00
178_M184_S0.5471.00
34_G255_Y0.5471.00
434_V441_V0.5461.00
275_E279_V0.5451.00
228_L312_S0.5421.00
277_P285_V0.5411.00
261_V264_S0.5401.00
83_F228_L0.5401.00
25_Q28_A0.5401.00
174_I178_M0.5391.00
53_L56_Y0.5391.00
184_S264_S0.5391.00
138_A306_C0.5391.00
53_L256_I0.5371.00
90_Y389_K0.5351.00
278_F281_V0.5351.00
124_Y127_P0.5331.00
67_M71_G0.5331.00
43_K366_T0.5321.00
102_T378_Y0.5291.00
121_Y279_V0.5291.00
109_S372_S0.5291.00
329_S333_L0.5281.00
445_L448_V0.5281.00
435_S447_I0.5271.00
440_P449_I0.5241.00
258_A278_F0.5241.00
417_A420_A0.5241.00
273_P276_S0.5231.00
114_D302_A0.5231.00
435_S446_L0.5211.00
141_I145_M0.5211.00
419_L423_L0.5211.00
441_V448_V0.5201.00
238_K241_P0.5191.00
435_S450_Y0.5191.00
143_L310_V0.5191.00
158_F162_L0.5191.00
206_M210_I0.5191.00
366_T369_T0.5181.00
33_I254_F0.5171.00
76_S395_P0.5161.00
191_S200_G0.5151.00
436_L449_I0.5151.00
407_L412_N0.5141.00
315_R333_L0.5131.00
112_M353_G0.5131.00
376_F379_I0.5131.00
433_R441_V0.5101.00
138_A142_L0.5101.00
403_F406_P0.5091.00
444_I450_Y0.5091.00
224_E380_W0.5081.00
59_T220_F0.5081.00
47_F211_L0.5081.00
15_L80_Y0.5081.00
14_T17_R0.5081.00
31_G225_L0.5071.00
377_I419_L0.5071.00
179_I265_I0.5061.00
221_V372_S0.5051.00
432_T441_V0.5051.00
393_T397_L0.5051.00
202_F206_M0.5051.00
431_D439_T0.5041.00
174_I287_I0.5041.00
152_L156_L0.5031.00
167_A293_I0.5031.00
232_E333_L0.5011.00
175_G180_F0.5011.00
388_M416_L0.5011.00
217_V422_V0.5001.00
198_H203_P0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3l1lA 2 0.8996 100 0.3 Contact Map
4djkA 2 0.8952 100 0.352 Contact Map
3giaA 1 0.9105 100 0.354 Contact Map
3dh4A 3 0.9127 99 0.855 Contact Map
2jlnA 1 0.8974 98.9 0.86 Contact Map
2xq2A 2 0.9148 98.8 0.862 Contact Map
4wgvA 2 0.8079 98.1 0.888 Contact Map
2a65A 2 0.917 97.2 0.908 Contact Map
4xp4A 1 0.9323 96.8 0.914 Contact Map
4us3A 1 0.8559 96.7 0.915 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.013 seconds.