YDGE - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YDGE - Uncharacterized N-acetyltransferase YdgE

UniProt:	P96703	Sequences: MAFTLEDMTEEEFEAFRGMSVQNFAKQNITSGTWTEKEAFEKSEQAYENMIPNGRDSSNHYFWNITNDQGERMGWLWLYADPLHPQKEAFIYSFGLYEAFRGKGLAQLALQTLDERARELGAERLALHVFAHNETAVYLYQKMGYAMTNIRMRKQLC	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	157 (130)
Sequences:	3557 (2869)
Seq/√Len:	251.6

ECOLI - PHNO YJGM MNAT YPEA YEDL RIMI YJAB YIAC YAFP
BACSU - YDGE YYCN PAIA YHFO YTMI YHDJ YSNE YQJY RIMI YUAI YWNH YYAR YESJ BLTD YBFA YBBJ SPSD YOBR
HALSA - Q9HQD2 Q9HMI8 Q9HMF0 Q9HSL3 Q9HRK6
SULSO - Y209 Q7LXZ8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
114_D	145_Y	4.486	1.00
76_L	113_L	2.888	1.00
107_Q	142_K	2.798	1.00
73_M	100_F	2.709	1.00
74_G	109_A	2.357	1.00
110_L	143_M	2.208	1.00
116_R	119_E	2.161	1.00
64_N	72_R	2.159	1.00
107_Q	143_M	2.153	1.00
114_D	125_L	2.106	1.00
127_L	140_Y	1.998	1.00
137_V	141_Q	1.930	1.00
66_T	72_R	1.918	1.00
74_G	96_L	1.893	1.00
89_A	117_A	1.873	1.00
112_T	115_E	1.866	1.00
66_T	70_G	1.827	1.00
30_T	97_Y	1.784	1.00
138_Y	141_Q	1.750	1.00
20_S	27_Q	1.728	1.00
67_N	100_F	1.660	1.00
100_F	103_K	1.604	1.00
61_Y	116_R	1.604	1.00
71_E	99_A	1.582	1.00
27_Q	31_S	1.516	1.00
71_E	100_F	1.516	1.00
63_W	112_T	1.486	1.00
44_E	48_E	1.473	1.00
45_Q	48_E	1.470	1.00
111_Q	143_M	1.467	1.00
80_A	122_A	1.466	1.00
67_N	103_K	1.431	1.00
136_A	140_Y	1.422	1.00
71_E	97_Y	1.400	1.00
107_Q	111_Q	1.377	1.00
67_N	73_M	1.374	1.00
127_L	136_A	1.372	1.00
147_M	150_I	1.353	1.00
78_L	117_A	1.296	1.00
63_W	116_R	1.291	1.00
26_K	30_T	1.240	1.00
91_I	110_L	1.237	1.00
129_V	133_N	1.216	1.00
65_I	109_A	1.210	1.00
22_Q	44_E	1.205	1.00
133_N	140_Y	1.188	1.00
117_A	125_L	1.179	1.00
48_E	52_P	1.175	1.00
111_Q	115_E	1.169	1.00
74_G	105_L	1.141	1.00
78_L	113_L	1.127	1.00
97_Y	100_F	1.122	1.00
112_T	116_R	1.120	1.00
88_E	126_A	1.110	1.00
62_F	66_T	1.098	1.00
20_S	24_F	1.082	1.00
65_I	105_L	1.065	1.00
89_A	122_A	1.062	1.00
94_F	127_L	1.056	1.00
110_L	140_Y	1.053	1.00
129_V	140_Y	1.052	1.00
101_R	135_T	1.048	1.00
23_N	26_K	1.034	1.00
141_Q	147_M	1.032	1.00
134_E	138_Y	1.030	1.00
22_Q	26_K	1.026	1.00
28_N	31_S	1.026	1.00
139_L	142_K	1.024	1.00
76_L	91_I	1.024	1.00
104_G	107_Q	1.022	1.00
75_W	95_G	1.020	1.00
88_E	124_R	1.011	1.00
115_E	119_E	0.992	1.00
24_F	27_Q	0.989	1.00
94_F	110_L	0.971	1.00
94_F	140_Y	0.967	1.00
96_L	106_A	0.966	1.00
62_F	77_W	0.959	1.00
43_S	46_A	0.951	1.00
27_Q	30_T	0.950	1.00
28_N	32_G	0.948	1.00
91_I	127_L	0.940	1.00
35_T	38_E	0.930	1.00
21_V	24_F	0.927	1.00
43_S	47_Y	0.925	1.00
79_Y	92_Y	0.923	1.00
135_T	138_Y	0.918	1.00
25_A	29_I	0.914	1.00
129_V	136_A	0.909	1.00
108_L	111_Q	0.899	1.00
137_V	147_M	0.881	1.00
127_L	133_N	0.879	1.00
110_L	139_L	0.870	1.00
115_E	118_R	0.865	0.99
96_L	109_A	0.859	0.99
27_Q	72_R	0.858	0.99
90_F	126_A	0.855	0.99
91_I	145_Y	0.844	0.99
27_Q	97_Y	0.842	0.99
116_R	120_L	0.841	0.99
29_I	33_T	0.839	0.99
18_G	21_V	0.830	0.99
46_A	49_N	0.828	0.99
30_T	98_E	0.825	0.99
19_M	22_Q	0.819	0.99
20_S	23_N	0.802	0.99
133_N	137_V	0.802	0.99
102_G	135_T	0.792	0.99
80_A	120_L	0.789	0.99
26_K	29_I	0.783	0.99
94_F	136_A	0.779	0.99
65_I	96_L	0.777	0.99
96_L	105_L	0.772	0.99
47_Y	50_M	0.770	0.99
36_E	39_A	0.768	0.99
133_N	136_A	0.764	0.99
73_M	105_L	0.764	0.99
91_I	94_F	0.760	0.99
78_L	116_R	0.754	0.99
45_Q	49_N	0.754	0.99
21_V	51_I	0.747	0.99
93_S	130_F	0.738	0.98
91_I	125_L	0.731	0.98
36_E	40_F	0.728	0.98
44_E	47_Y	0.716	0.98
108_L	115_E	0.708	0.98
114_D	143_M	0.706	0.98
136_A	139_L	0.698	0.98
65_I	74_G	0.696	0.98
134_E	141_Q	0.695	0.98
110_L	136_A	0.688	0.97
19_M	23_N	0.688	0.97
18_G	44_E	0.686	0.97
38_E	41_E	0.684	0.97
42_K	47_Y	0.684	0.97
22_Q	25_A	0.682	0.97
77_W	92_Y	0.674	0.97
95_G	130_F	0.667	0.97
94_F	143_M	0.665	0.97
25_A	32_G	0.662	0.97
139_L	143_M	0.661	0.97
22_Q	28_N	0.653	0.97
132_H	137_V	0.650	0.96
94_F	139_L	0.622	0.95
110_L	127_L	0.620	0.95
24_F	32_G	0.613	0.95
126_A	148_T	0.610	0.95
35_T	40_F	0.605	0.95
78_L	89_A	0.601	0.95
60_H	66_T	0.597	0.94
102_G	138_Y	0.596	0.94
35_T	97_Y	0.588	0.94
58_S	67_N	0.584	0.94
87_K	123_E	0.581	0.93
93_S	128_H	0.580	0.93
107_Q	139_L	0.580	0.93
81_D	122_A	0.579	0.93
117_A	122_A	0.575	0.93
52_P	57_S	0.574	0.93
47_Y	51_I	0.571	0.93
57_S	60_H	0.570	0.93
87_K	122_A	0.570	0.93
118_R	141_Q	0.568	0.93
94_F	109_A	0.565	0.93
39_A	45_Q	0.558	0.92
105_L	108_L	0.558	0.92
110_L	145_Y	0.556	0.92
51_I	54_G	0.554	0.92
24_F	31_S	0.554	0.92
141_Q	146_A	0.552	0.92
40_F	128_H	0.549	0.91
130_F	133_N	0.549	0.91
124_R	148_T	0.548	0.91
101_R	136_A	0.545	0.91
19_M	27_Q	0.542	0.91
28_N	75_W	0.540	0.91
102_G	139_L	0.539	0.91
111_Q	142_K	0.536	0.90
80_A	89_A	0.535	0.90
131_A	151_R	0.528	0.90
62_F	75_W	0.527	0.90
24_F	28_N	0.526	0.90
94_F	133_N	0.525	0.90
33_T	78_L	0.522	0.89
40_F	46_A	0.520	0.89
137_V	150_I	0.518	0.89
67_N	71_E	0.515	0.89
73_M	97_Y	0.513	0.88
65_I	68_D	0.512	0.88
131_A	150_I	0.509	0.88
90_F	128_H	0.508	0.88
91_I	113_L	0.505	0.88
68_D	71_E	0.502	0.87
74_G	113_L	0.500	0.87
114_D	139_L	0.500	0.87

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ufhA	3	0.9873	99.9	0.323	Contact Map
1on0A	4	0.9936	99.8	0.335	Contact Map
3fixA	2	0.9554	99.8	0.372	Contact Map
1vkcA	2	0.9236	99.8	0.395	Contact Map
3fynA	2	0.8726	99.8	0.399	Contact Map
2j8mA	2	0.9427	99.8	0.401	Contact Map
1p0hA	1	0.9682	99.7	0.408	Contact Map
1tiqA	1	0.9809	99.7	0.409	Contact Map
1z4eA	2	0.9299	99.7	0.41	Contact Map
3jvnA	2	0.7452	99.7	0.413	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0068 seconds.