GREMLIN Database
YDCQ - Ftsk domain-containing protein YdcQ
UniProt: P96634 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 480 (428)
Sequences: 3311 (1886)
Seq/√Len: 91.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
293_S326_I5.4671.00
249_K441_F4.1751.00
104_A440_D3.9721.00
56_Q59_K3.7491.00
105_K205_D3.5161.00
248_I260_I2.9001.00
106_M206_D2.8091.00
299_E303_E2.8011.00
130_S135_T2.7911.00
85_A88_F2.7781.00
63_W66_P2.7671.00
247_I365_V2.7021.00
52_F55_S2.6891.00
303_E321_L2.6671.00
74_C85_A2.6501.00
135_T156_D2.5791.00
71_S78_I2.5491.00
214_L218_K2.5131.00
313_G323_P2.4561.00
73_L88_F2.4521.00
121_R151_I2.4481.00
67_L71_S2.4451.00
395_D405_V2.4441.00
373_A400_M2.4201.00
312_T315_N2.4141.00
326_I362_Y2.4061.00
248_I327_F2.3831.00
54_L58_I2.3341.00
298_M356_L2.3071.00
63_W67_L2.2841.00
155_M164_F2.2211.00
444_S448_A2.2071.00
251_C256_A2.1811.00
67_L74_C2.1611.00
71_S74_C2.1341.00
164_F189_V2.1261.00
230_M388_V2.0941.00
442_M446_K2.0481.00
63_W71_S2.0351.00
126_N139_R2.0191.00
351_K379_G2.0161.00
339_D344_N2.0081.00
47_E50_I2.0001.00
100_R208_V1.9931.00
70_K78_I1.9921.00
222_W420_A1.9881.00
66_P71_S1.9851.00
62_E66_P1.9831.00
204_I208_V1.9771.00
243_F247_I1.9741.00
45_W49_L1.9701.00
127_E131_K1.9501.00
42_F49_L1.9401.00
235_G238_G1.9251.00
66_P78_I1.9231.00
66_P70_K1.9211.00
255_G320_G1.9081.00
115_K119_K1.8891.00
41_M44_F1.8871.00
199_K415_T1.8561.00
249_K435_V1.8471.00
243_F388_V1.8211.00
63_W70_K1.8171.00
66_P74_C1.8121.00
30_A37_F1.8001.00
74_C78_I1.7991.00
439_Y443_S1.7921.00
67_L73_L1.7751.00
222_W227_L1.7681.00
85_A89_L1.7621.00
265_N356_L1.7571.00
123_I127_E1.7441.00
42_F50_I1.7241.00
211_N388_V1.7151.00
328_F331_Y1.7101.00
74_C88_F1.7061.00
67_L70_K1.6901.00
296_G299_E1.6811.00
44_F49_L1.6681.00
123_I126_N1.6391.00
74_C81_G1.6341.00
304_M360_A1.6161.00
122_K142_Y1.5981.00
75_S78_I1.5861.00
62_E73_L1.5841.00
76_V80_V1.5711.00
55_S58_I1.5701.00
99_H444_S1.5631.00
152_R186_E1.5611.00
243_F246_T1.5511.00
66_P73_L1.5391.00
37_F41_M1.5181.00
71_S75_S1.5121.00
125_S171_L1.5111.00
204_I435_V1.5091.00
443_S447_N1.5021.00
37_F43_L1.4931.00
52_F67_L1.4911.00
121_R197_V1.4701.00
35_P39_L1.4701.00
80_V87_Y1.4661.00
254_L257_D1.4651.00
67_L75_S1.4631.00
230_M365_V1.4601.00
119_K123_I1.4380.99
273_E446_K1.4220.99
331_Y350_M1.4190.99
107_I203_S1.4180.99
126_N138_P1.4100.99
30_A33_F1.4050.99
74_C91_F1.3990.99
70_K74_C1.3860.99
444_S447_N1.3850.99
260_I327_F1.3790.99
265_N302_D1.3770.99
64_N71_S1.3710.99
118_V122_K1.3690.99
220_I430_F1.3640.99
280_Y289_C1.3630.99
67_L78_I1.3590.99
33_F40_S1.3480.99
328_F366_L1.3440.99
70_K81_G1.3310.99
70_K87_Y1.3310.99
206_D213_V1.3200.99
43_L47_E1.3110.99
88_F91_F1.3100.99
46_R50_I1.3050.99
353_L357_G1.3040.99
302_D306_Q1.2980.99
39_L43_L1.2860.99
171_L174_G1.2800.99
64_N68_I1.2730.99
31_I38_L1.2700.99
46_R49_L1.2700.99
74_C77_L1.2680.99
251_C325_F1.2570.99
162_N166_D1.2510.98
128_T171_L1.2510.98
73_L87_Y1.2510.98
85_A91_F1.2410.98
40_S44_F1.2400.98
33_F37_F1.2360.98
44_F50_I1.2310.98
42_F47_E1.2310.98
125_S191_F1.2290.98
73_L77_L1.2260.98
73_L85_A1.2250.98
31_I45_W1.2240.98
71_S85_A1.2190.98
67_L88_F1.2150.98
67_L81_G1.2110.98
73_L90_L1.2070.98
90_L94_Y1.2060.98
309_N319_L1.2030.98
38_L45_W1.1990.98
63_W78_I1.1980.98
292_K457_A1.1870.98
30_A44_F1.1800.98
209_A365_V1.1790.98
140_M188_F1.1790.98
58_I70_K1.1780.98
82_S85_A1.1750.98
85_A93_S1.1750.98
74_C90_L1.1660.98
174_G187_G1.1660.98
64_N67_L1.1650.98
31_I35_P1.1640.98
294_V298_M1.1630.98
41_M49_L1.1610.98
88_F93_S1.1570.97
388_V418_G1.1530.97
90_L93_S1.1520.97
69_I73_L1.1470.97
32_I36_V1.1340.97
226_K415_T1.1260.97
77_L93_S1.1190.97
176_F187_G1.1170.97
117_N197_V1.1110.97
87_Y90_L1.1070.97
78_I85_A1.1050.97
64_N70_K1.1010.97
51_H60_N1.1010.97
73_L84_V1.1010.97
331_Y335_M1.0990.97
41_M47_E1.0940.96
73_L91_F1.0930.96
35_P42_F1.0910.96
81_G85_A1.0880.96
41_M45_W1.0760.96
61_F64_N1.0720.96
140_M154_A1.0690.96
293_S362_Y1.0690.96
105_K206_D1.0670.96
33_F41_M1.0610.96
35_P45_W1.0590.96
31_I34_V1.0580.96
93_S96_K1.0530.96
397_G400_M1.0530.96
45_W48_Q1.0520.96
137_F153_I1.0500.95
307_M316_Y1.0420.95
155_M159_R1.0370.95
62_E69_I1.0350.95
68_I84_V1.0340.95
74_C87_Y1.0310.95
179_L182_K1.0260.95
286_I294_V1.0240.95
85_A90_L1.0210.95
62_E70_K1.0200.95
67_L89_L1.0150.95
87_Y94_Y1.0150.95
463_G466_S1.0150.95
455_A459_A1.0110.94
331_Y366_L1.0100.94
147_N431_Y1.0060.94
309_N315_N1.0010.94
104_A437_K0.9990.94
63_W87_Y0.9940.94
74_C89_L0.9930.94
389_S396_T0.9930.94
404_D427_V0.9900.94
106_M203_S0.9890.94
229_H236_T0.9860.94
72_V75_S0.9840.94
201_R415_T0.9780.93
80_V91_F0.9780.93
203_S206_D0.9770.93
258_V325_F0.9760.93
70_K77_L0.9670.93
122_K139_R0.9650.93
62_E67_L0.9650.93
125_S169_K0.9640.93
45_W50_I0.9620.93
445_I448_A0.9580.93
70_K75_S0.9550.93
261_L286_I0.9540.93
455_A458_T0.9490.92
53_D59_K0.9380.92
336_D355_M0.9280.91
70_K92_D0.9250.91
73_L93_S0.9220.91
89_L92_D0.9200.91
37_F50_I0.9190.91
456_Q459_A0.9170.91
71_S84_V0.9160.91
55_S59_K0.9140.91
86_S90_L0.9110.91
293_S353_L0.9060.90
244_M331_Y0.9050.90
118_V144_V0.9020.90
457_A461_A0.9020.90
77_L80_V0.8980.90
373_A397_G0.8950.90
54_L60_N0.8930.90
51_H55_S0.8930.90
118_V142_Y0.8910.90
243_F390_L0.8900.90
74_C86_S0.8890.90
31_I39_L0.8880.90
78_I90_L0.8870.90
37_F49_L0.8860.89
75_S87_Y0.8850.89
295_D299_E0.8820.89
43_L49_L0.8800.89
83_I88_F0.8790.89
456_Q460_V0.8750.89
42_F45_W0.8750.89
270_D442_M0.8750.89
78_I81_G0.8730.89
75_S80_V0.8710.89
440_D443_S0.8670.88
127_E130_S0.8660.88
69_I77_L0.8660.88
259_R293_S0.8640.88
295_D356_L0.8620.88
66_P75_S0.8580.88
39_L47_E0.8570.88
232_I430_F0.8540.88
446_K453_E0.8540.88
37_F44_F0.8530.88
460_V465_V0.8510.88
70_K93_S0.8510.88
147_N199_K0.8490.87
235_G391_G0.8490.87
312_T351_K0.8480.87
67_L85_A0.8480.87
60_N63_W0.8450.87
84_V88_F0.8450.87
66_P69_I0.8440.87
60_N67_L0.8430.87
78_I82_S0.8390.87
63_W74_C0.8330.86
71_S89_L0.8320.86
161_Q182_K0.8310.86
67_L87_Y0.8290.86
66_P80_V0.8260.86
259_R277_K0.8260.86
34_V39_L0.8250.86
68_I73_L0.8250.86
61_F66_P0.8230.86
61_F76_V0.8230.86
30_A40_S0.8220.86
30_A41_M0.8190.85
51_H59_K0.8170.85
97_I448_A0.8170.85
121_R124_F0.8160.85
62_E65_V0.8080.85
55_S66_P0.8080.85
37_F40_S0.8050.84
79_A83_I0.8040.84
45_W51_H0.8020.84
35_P44_F0.7990.84
366_L384_F0.7990.84
87_Y91_F0.7990.84
54_L57_V0.7980.84
78_I87_Y0.7960.84
73_L76_V0.7910.83
34_V38_L0.7890.83
311_K438_G0.7870.83
128_T131_K0.7870.83
52_F58_I0.7860.83
87_Y96_K0.7850.83
68_I87_Y0.7850.83
126_N137_F0.7850.83
64_N73_L0.7840.83
73_L80_V0.7830.83
291_R349_Y0.7820.83
177_C181_D0.7800.83
373_A396_T0.7760.82
61_F65_V0.7750.82
51_H54_L0.7740.82
67_L77_L0.7740.82
65_V87_Y0.7730.82
64_N80_V0.7730.82
71_S82_S0.7730.82
169_K181_D0.7720.82
71_S81_G0.7680.82
70_K90_L0.7670.81
55_S70_K0.7660.81
54_L67_L0.7650.81
63_W68_I0.7650.81
64_N81_G0.7650.81
98_L103_I0.7640.81
66_P87_Y0.7640.81
58_I73_L0.7630.81
84_V91_F0.7620.81
44_F47_E0.7590.81
64_N90_L0.7580.81
75_S88_F0.7570.81
222_W422_V0.7570.81
36_V40_S0.7570.81
31_I41_M0.7560.81
265_N305_K0.7560.81
266_A304_M0.7560.81
55_S67_L0.7540.80
77_L85_A0.7530.80
75_S91_F0.7520.80
183_Q188_F0.7490.80
92_D96_K0.7480.80
445_I457_A0.7480.80
74_C82_S0.7470.80
53_D58_I0.7460.80
48_Q52_F0.7450.80
75_S82_S0.7320.78
117_N120_V0.7310.78
35_P41_M0.7310.78
41_M54_L0.7310.78
87_Y93_S0.7290.78
53_D56_Q0.7290.78
179_L189_V0.7280.78
454_G458_T0.7270.78
161_Q189_V0.7250.78
89_L93_S0.7220.77
119_K142_Y0.7220.77
268_L390_L0.7210.77
66_P76_V0.7200.77
73_L82_S0.7200.77
339_D351_K0.7200.77
71_S88_F0.7190.77
31_I46_R0.7180.77
66_P82_S0.7150.77
70_K73_L0.7150.77
131_K157_M0.7140.77
52_F60_N0.7130.77
92_D95_K0.7120.76
78_I83_I0.7120.76
36_V43_L0.7090.76
59_K63_W0.7080.76
60_N66_P0.7080.76
74_C84_V0.7080.76
235_G393_M0.7070.76
62_E68_I0.7060.76
83_I86_S0.7060.76
59_K64_N0.7040.76
386_F422_V0.7040.76
39_L77_L0.7020.75
318_Y428_L0.7010.75
68_I78_I0.6990.75
38_L41_M0.6980.75
245_L271_L0.6970.75
82_S93_S0.6940.75
138_P154_A0.6910.74
60_N70_K0.6870.74
30_A39_L0.6870.74
62_E86_S0.6870.74
70_K76_V0.6860.74
69_I87_Y0.6860.74
71_S87_Y0.6840.74
447_N450_V0.6790.73
259_R457_A0.6790.73
443_S446_K0.6780.73
31_I37_F0.6780.73
421_N425_G0.6760.73
81_G86_S0.6750.73
282_Q288_M0.6750.73
48_Q51_H0.6750.73
417_R429_E0.6740.72
396_T400_M0.6730.72
54_L59_K0.6720.72
45_W52_F0.6720.72
43_L48_Q0.6700.72
42_F46_R0.6690.72
73_L79_A0.6690.72
76_V92_D0.6650.71
69_I74_C0.6650.71
452_V461_A0.6650.71
459_A463_G0.6640.71
72_V81_G0.6630.71
120_V124_F0.6610.71
283_K337_L0.6590.71
165_L291_R0.6550.70
58_I62_E0.6550.70
30_A43_L0.6530.70
63_W85_A0.6530.70
84_V87_Y0.6530.70
156_D172_E0.6510.70
49_L55_S0.6490.70
73_L81_G0.6490.70
350_M364_L0.6480.69
30_A34_V0.6470.69
67_L76_V0.6460.69
89_L96_K0.6430.69
37_F47_E0.6410.69
67_L84_V0.6410.69
62_E74_C0.6400.69
201_R434_I0.6400.69
84_V90_L0.6390.68
37_F45_W0.6380.68
143_Q188_F0.6380.68
151_I161_Q0.6380.68
40_S49_L0.6370.68
66_P81_G0.6360.68
58_I66_P0.6340.68
61_F70_K0.6330.68
32_I35_P0.6330.68
264_K329_D0.6330.68
165_L189_V0.6310.67
168_G409_Y0.6310.67
173_N182_K0.6300.67
230_M386_F0.6290.67
75_S89_L0.6280.67
39_L44_F0.6260.67
33_F47_E0.6260.67
438_G442_M0.6260.67
449_L453_E0.6250.67
64_N92_D0.6240.67
86_S93_S0.6240.67
66_P90_L0.6200.66
90_L95_K0.6200.66
137_F431_Y0.6190.66
289_C375_Y0.6190.66
418_G430_F0.6190.66
357_G362_Y0.6150.65
351_K354_V0.6150.65
69_I92_D0.6140.65
170_D173_N0.6130.65
266_A431_Y0.6130.65
76_V87_Y0.6120.65
86_S89_L0.6110.65
67_L93_S0.6110.65
82_S94_Y0.6100.65
454_G457_A0.6090.65
116_E120_V0.6080.65
65_V71_S0.6070.64
68_I74_C0.6070.64
65_V77_L0.6040.64
77_L84_V0.6030.64
248_I258_V0.6030.64
147_N304_M0.6020.64
150_Y339_D0.6020.64
54_L73_L0.5970.63
70_K85_A0.5960.63
68_I71_S0.5950.63
182_K189_V0.5950.63
358_R369_Q0.5940.63
66_P84_V0.5940.63
264_K369_Q0.5920.63
50_I60_N0.5910.62
384_F405_V0.5900.62
150_Y216_L0.5890.62
76_V81_G0.5860.62
31_I42_F0.5850.62
353_L373_A0.5830.61
147_N430_F0.5830.61
88_F94_Y0.5820.61
57_V60_N0.5820.61
74_C83_I0.5810.61
424_T428_L0.5810.61
81_G90_L0.5810.61
150_Y180_V0.5790.61
98_L102_K0.5790.61
168_G179_L0.5790.61
421_N424_T0.5780.61
63_W80_V0.5770.61
75_S85_A0.5750.60
62_E90_L0.5750.60
59_K90_L0.5730.60
54_L93_S0.5700.60
57_V82_S0.5700.60
45_W54_L0.5700.60
232_I247_I0.5690.60
64_N75_S0.5690.60
458_T461_A0.5680.59
73_L78_I0.5670.59
328_F364_L0.5660.59
32_I39_L0.5650.59
87_Y92_D0.5640.59
34_V40_S0.5640.59
31_I48_Q0.5620.59
36_V41_M0.5610.58
56_Q71_S0.5600.58
34_V45_W0.5600.58
39_L46_R0.5600.58
43_L58_I0.5570.58
176_F191_F0.5560.58
125_S177_C0.5550.58
67_L91_F0.5540.57
446_K450_V0.5540.57
77_L88_F0.5530.57
54_L91_F0.5530.57
47_E87_Y0.5530.57
31_I43_L0.5520.57
266_A360_A0.5520.57
69_I91_F0.5520.57
104_A203_S0.5510.57
163_R166_D0.5510.57
43_L50_I0.5510.57
265_N304_M0.5500.57
45_W55_S0.5500.57
34_V37_F0.5490.57
54_L61_F0.5490.57
235_G382_D0.5480.57
77_L90_L0.5480.57
73_L86_S0.5470.57
67_L82_S0.5460.56
35_P40_S0.5460.56
31_I44_F0.5450.56
150_Y223_Q0.5450.56
47_E52_F0.5450.56
113_Y117_N0.5440.56
376_L400_M0.5440.56
64_N78_I0.5420.56
39_L42_F0.5410.56
57_V65_V0.5410.56
71_S83_I0.5390.55
388_V420_A0.5390.55
240_K300_R0.5390.55
80_V88_F0.5390.55
34_V43_L0.5390.55
244_M327_F0.5380.55
81_G87_Y0.5370.55
91_F95_K0.5370.55
30_A36_V0.5360.55
265_N281_S0.5350.55
79_A91_F0.5350.55
338_L345_E0.5340.55
77_L81_G0.5340.55
244_M268_L0.5340.55
66_P85_A0.5330.55
71_S86_S0.5330.55
64_N74_C0.5320.54
34_V42_F0.5320.54
330_E358_R0.5320.54
63_W81_G0.5310.54
458_T462_S0.5300.54
116_E463_G0.5290.54
390_L415_T0.5290.54
159_R164_F0.5290.54
99_H102_K0.5280.54
64_N82_S0.5270.54
204_I249_K0.5270.54
41_M50_I0.5270.54
86_S91_F0.5260.54
232_I243_F0.5260.54
33_F45_W0.5230.53
39_L45_W0.5230.53
70_K86_S0.5230.53
39_L82_S0.5220.53
391_G426_S0.5210.53
101_Q205_D0.5200.53
36_V46_R0.5180.53
236_T264_K0.5180.53
56_Q66_P0.5180.53
88_F92_D0.5170.52
43_L46_R0.5170.52
51_H61_F0.5170.52
69_I81_G0.5170.52
454_G459_A0.5160.52
36_V39_L0.5150.52
154_A187_G0.5140.52
83_I90_L0.5130.52
70_K82_S0.5120.52
58_I68_I0.5110.52
68_I72_V0.5110.52
452_V459_A0.5100.51
63_W75_S0.5100.51
88_F95_K0.5100.51
394_S397_G0.5090.51
229_H369_Q0.5090.51
34_V49_L0.5080.51
63_W73_L0.5080.51
48_Q59_K0.5080.51
77_L464_S0.5080.51
459_A462_S0.5070.51
43_L54_L0.5070.51
331_Y426_S0.5070.51
150_Y384_F0.5070.51
68_I96_K0.5060.51
56_Q60_N0.5050.51
38_L93_S0.5050.51
287_L349_Y0.5050.51
85_A92_D0.5050.51
38_L50_I0.5040.51
88_F96_K0.5040.51
62_E71_S0.5030.50
153_I431_Y0.5030.50
64_N89_L0.5030.50
37_F48_Q0.5030.50
33_F43_L0.5030.50
214_L220_I0.5010.50
384_F427_V0.5000.50
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2iusA 1 0.7229 100 0.426 Contact Map
2iutA 2 0.7375 100 0.462 Contact Map
4nh0A 1 0.5583 100 0.717 Contact Map
4lyaA 1 0.5708 100 0.757 Contact Map
4d2iA 3 0.6771 99.9 0.802 Contact Map
4ag6A 2 0.4854 99.8 0.82 Contact Map
1e9rA 3 0.5375 99.6 0.861 Contact Map
2r2aA 1 0.3812 98.8 0.901 Contact Map
1jbkA 1 0.3688 98.4 0.913 Contact Map
2r8rA 1 0.425 98.2 0.919 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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