CSHA - BACSU - GREMLIN Contacts

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CSHA - DEAD-box ATP-dependent RNA helicase CshA

UniProt:	P96614	Sequences: MTITFQDFNLSSDLMKAINRMGFEEATPIQAQTIPLGLSNKDVIGQAQTGTGKTAAFGIPLVEKINPESPNIQAIVIAPTRELAIQVSEELYKIGQDKRAKVLPIYGGQDIGRQIRALKKNPNIIVGTPGRLLDHINRRTIRLNNVNTVVMDEADEMLNMGFIDDIESILSNVPSEHQTLLFSATMPAPIKRIAERFMTEPEHVKVKAKEMTVSNIQQFYLEVQERKKFDTLTRLLDIQSPELAIVFGRTKRRVDELAEALNLRGYAAEGIHGDLTQAKRMVALRKFKEGAIEVLVATDVAARGLDISGVTHVYNFDVPQDPESYVHRIGRTGRAGKTGMAMTFITPREKSMLRAIEQTTKRKMDRMKEPTLDEALEGQQQVTVERLRTTISENNLNFYMTAAAELLEDHDAVTVVAAAIKMATKEPDDTPVRLTDEAPMVSKRYKNQRSSKRRDGQGGGYRGGKGKSNNRSSYDKKRSNDRRSSGDRRQKKSY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	494 (400)
Sequences:	22068 (13222)
Seq/√Len:	661.1

ECOLI - DEAD RECQ RHLE SRMB DBPA RECG RHLB YFJK YEJH RAPA
BACSU - CSHA DBPA RECQ RECG CSHB RECS YPRA YFML COMFA YWQA YQHH
HALSA - HELS Q9HN80 Q9HNB2 RAD25 Q9HMW5 O52003 Q9HQA5 O51997
SULSO - Q981C8 Q97Y93 Q97WW1 HELS HELX Q97X74 Q97YC4 Q980C0 Q97ZF9 Q97WT0 Q97X64 Q97ZF3 Q97ZV2 Q97YQ4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
58_G	91_L	5.637	1.00
61_L	74_A	4.702	1.00
78_A	87_V	3.942	1.00
37_G	180_L	3.920	1.00
127_G	132_L	3.507	1.00
286_K	291_A	3.473	1.00
251_K	274_D	3.439	1.00
29_I	45_G	3.334	1.00
269_E	292_I	3.243	1.00
233_T	264_R	3.042	1.00
41_K	202_E	3.014	1.00
57_F	150_V	2.955	1.00
248_G	254_V	2.903	1.00
285_R	289_E	2.865	1.00
48_Q	51_T	2.743	1.00
258_A	268_A	2.722	1.00
88_S	102_V	2.681	1.00
88_S	92_Y	2.644	1.00
266_Y	294_V	2.601	1.00
353_L	357_E	2.581	1.00
329_I	341_A	2.574	1.00
282_V	286_K	2.514	1.00
135_H	140_T	2.505	1.00
23_F	55_A	2.501	1.00
248_G	257_L	2.474	1.00
269_E	286_K	2.457	1.00
255_D	270_G	2.370	1.00
217_Q	340_M	2.351	1.00
318_V	343_T	2.350	1.00
73_Q	147_N	2.271	1.00
248_G	296_V	2.216	1.00
90_E	93_K	2.208	1.00
164_D	168_S	2.054	1.00
301_A	305_L	2.047	1.00
309_G	337_K	1.993	1.00
213_V	216_I	1.964	1.00
237_D	264_R	1.958	1.00
242_E	311_T	1.956	1.00
163_I	166_I	1.939	1.00
88_S	104_P	1.939	1.00
103_L	122_P	1.927	1.00
254_V	272_H	1.906	1.00
267_A	293_E	1.888	1.00
163_I	167_E	1.883	1.00
253_R	317_D	1.866	1.00
312_H	340_M	1.864	1.00
258_A	270_G	1.854	1.00
218_Q	329_I	1.853	1.00
74_A	148_T	1.851	1.00
91_L	124_I	1.837	1.00
297_A	301_A	1.836	1.00
165_D	168_S	1.833	1.00
156_E	159_N	1.806	1.00
219_F	340_M	1.804	1.00
261_L	296_V	1.794	1.00
45_G	182_F	1.778	1.00
37_G	43_V	1.777	1.00
137_N	168_S	1.747	1.00
231_T	234_R	1.738	1.00
61_L	150_V	1.726	1.00
191_K	203_H	1.722	1.00
269_E	283_A	1.721	1.00
110_D	113_R	1.720	1.00
191_K	195_E	1.715	1.00
91_L	102_V	1.700	1.00
258_A	262_N	1.698	1.00
183_S	186_M	1.693	1.00
232_L	314_Y	1.678	1.00
36_L	202_E	1.667	1.00
73_Q	123_N	1.662	1.00
21_M	93_K	1.645	1.00
218_Q	325_Y	1.633	1.00
61_L	148_T	1.631	1.00
244_A	312_H	1.620	1.00
85_I	281_M	1.614	1.00
276_T	279_K	1.614	1.00
244_A	314_Y	1.612	1.00
38_L	63_E	1.594	1.00
201_P	204_V	1.589	1.00
164_D	167_E	1.573	1.00
64_K	148_T	1.570	1.00
281_M	285_R	1.567	1.00
229_F	260_A	1.546	1.00
254_V	270_G	1.545	1.00
36_L	39_S	1.538	1.00
71_N	145_N	1.530	1.00
91_L	126_V	1.526	1.00
133_L	168_S	1.525	1.00
75_I	146_V	1.515	1.00
257_L	296_V	1.505	1.00
190_I	193_I	1.502	1.00
77_I	132_L	1.494	1.00
57_F	87_V	1.489	1.00
122_P	125_I	1.472	1.00
42_D	181_L	1.468	1.00
315_N	343_T	1.463	1.00
89_E	93_K	1.462	1.00
312_H	342_M	1.448	1.00
57_F	182_F	1.447	1.00
371_T	374_E	1.425	1.00
349_E	353_L	1.414	1.00
188_A	192_R	1.398	1.00
244_A	294_V	1.397	1.00
149_V	170_L	1.392	1.00
225_E	253_R	1.387	1.00
246_V	294_V	1.383	1.00
103_L	125_I	1.378	1.00
235_L	238_I	1.376	1.00
260_A	264_R	1.369	1.00
191_K	194_A	1.369	1.00
233_T	237_D	1.364	1.00
189_P	192_R	1.353	1.00
315_N	329_I	1.350	1.00
84_A	104_P	1.339	1.00
412_A	415_V	1.338	1.00
361_K	364_M	1.333	1.00
235_L	342_M	1.333	1.00
112_G	116_R	1.328	1.00
167_E	196_R	1.327	1.00
232_L	316_F	1.326	1.00
370_P	374_E	1.321	1.00
258_A	296_V	1.316	1.00
35_P	39_S	1.312	1.00
354_R	357_E	1.307	1.00
168_S	172_N	1.307	1.00
187_P	190_I	1.307	1.00
241_P	244_A	1.305	1.00
419_A	422_M	1.300	1.00
216_I	333_G	1.297	1.00
411_D	415_V	1.287	1.00
182_F	185_T	1.273	1.00
36_L	204_V	1.266	1.00
62_V	95_G	1.264	1.00
136_I	172_N	1.264	1.00
275_L	283_A	1.262	1.00
190_I	194_A	1.260	1.00
74_A	150_V	1.259	1.00
357_E	363_K	1.252	1.00
55_A	59_I	1.251	1.00
250_T	253_R	1.226	1.00
103_L	117_A	1.225	1.00
189_P	193_I	1.213	1.00
32_Q	36_L	1.213	1.00
378_G	381_Q	1.209	1.00
155_D	303_R	1.204	1.00
149_V	179_T	1.204	1.00
101_K	123_N	1.204	1.00
243_L	309_G	1.203	1.00
78_A	84_A	1.202	1.00
168_S	171_S	1.199	1.00
279_K	283_A	1.195	1.00
46_Q	205_K	1.181	1.00
61_L	76_V	1.164	1.00
279_K	282_V	1.160	1.00
162_F	166_I	1.155	1.00
167_E	171_S	1.142	1.00
350_K	354_R	1.142	1.00
127_G	141_I	1.142	1.00
259_E	262_N	1.141	1.00
253_R	256_E	1.130	1.00
174_P	177_H	1.121	1.00
360_T	363_K	1.116	1.00
28_P	32_Q	1.109	1.00
66_N	69_S	1.107	1.00
229_F	316_F	1.104	1.00
237_D	266_Y	1.097	1.00
33_T	56_A	1.094	1.00
64_K	147_N	1.093	1.00
85_I	89_E	1.085	1.00
232_L	246_V	1.082	1.00
417_A	420_I	1.081	1.00
284_L	307_I	1.079	1.00
40_N	64_K	1.078	1.00
319_P	325_Y	1.077	1.00
65_I	100_A	1.077	1.00
228_K	317_D	1.074	1.00
133_L	137_N	1.069	1.00
247_F	328_R	1.062	1.00
193_I	197_F	1.060	1.00
255_D	272_H	1.054	1.00
371_T	375_A	1.053	1.00
77_I	161_G	1.046	1.00
282_V	285_R	1.040	1.00
257_L	316_F	1.029	1.00
315_N	328_R	1.028	1.00
379_Q	383_T	1.026	1.00
370_P	373_D	1.018	1.00
355_A	358_Q	1.018	1.00
399_Y	403_A	1.013	1.00
406_L	409_D	1.011	1.00
234_R	238_I	1.007	1.00
62_V	66_N	1.004	1.00
353_L	363_K	1.003	1.00
285_R	288_K	1.000	1.00
359_T	363_K	0.995	1.00
254_V	258_A	0.994	1.00
245_I	297_A	0.993	1.00
262_N	268_A	0.990	1.00
254_V	296_V	0.988	1.00
224_Q	227_K	0.987	1.00
321_D	324_S	0.986	1.00
62_V	65_I	0.983	1.00
313_V	332_T	0.983	1.00
403_A	406_L	0.982	1.00
352_M	355_A	0.982	1.00
182_F	186_M	0.982	1.00
283_A	292_I	0.981	1.00
40_N	178_Q	0.978	1.00
88_S	126_V	0.971	1.00
229_F	257_L	0.970	1.00
416_V	420_I	0.970	1.00
271_I	301_A	0.968	1.00
236_L	244_A	0.966	1.00
419_A	423_A	0.966	1.00
420_I	423_A	0.963	1.00
233_T	260_A	0.958	1.00
89_E	92_Y	0.957	1.00
407_L	411_D	0.957	1.00
215_N	338_T	0.956	1.00
154_A	181_L	0.954	1.00
350_K	353_L	0.950	1.00
275_L	279_K	0.940	1.00
383_T	387_L	0.937	1.00
95_G	98_K	0.935	1.00
83_L	304_G	0.933	1.00
372_L	376_L	0.930	1.00
37_G	60_P	0.926	1.00
357_E	360_T	0.923	1.00
408_E	411_D	0.923	1.00
242_E	338_T	0.922	1.00
235_L	314_Y	0.919	1.00
396_L	399_Y	0.918	1.00
404_A	408_E	0.911	1.00
286_K	292_I	0.904	1.00
401_T	404_A	0.902	1.00
403_A	407_L	0.901	1.00
356_I	360_T	0.901	1.00
77_I	127_G	0.889	1.00
158_L	161_G	0.888	1.00
408_E	412_A	0.887	1.00
243_L	290_G	0.886	1.00
410_H	413_V	0.884	1.00
243_L	310_V	0.883	1.00
165_D	169_I	0.880	1.00
409_D	412_A	0.878	1.00
234_R	237_D	0.878	1.00
42_D	179_T	0.875	1.00
235_L	312_H	0.866	1.00
416_V	419_A	0.865	1.00
399_Y	402_A	0.863	1.00
59_I	63_E	0.861	1.00
192_R	195_E	0.854	1.00
287_F	295_L	0.853	1.00
54_T	87_V	0.852	1.00
406_L	410_H	0.844	1.00
36_L	43_V	0.843	1.00
230_D	233_T	0.840	1.00
59_I	62_V	0.836	1.00
42_D	201_P	0.835	1.00
229_F	233_T	0.833	1.00
355_A	359_T	0.829	1.00
76_V	91_L	0.828	1.00
412_A	416_V	0.828	1.00
233_T	266_Y	0.826	1.00
44_I	186_M	0.825	1.00
229_F	264_R	0.822	1.00
411_D	417_A	0.819	1.00
61_L	91_L	0.819	1.00
380_Q	383_T	0.818	1.00
106_Y	109_Q	0.818	1.00
157_M	160_M	0.817	1.00
369_E	373_D	0.814	1.00
414_T	417_A	0.809	1.00
256_E	260_A	0.809	1.00
380_Q	384_V	0.809	1.00
138_R	145_N	0.808	1.00
405_E	410_H	0.806	1.00
404_A	410_H	0.804	1.00
406_L	415_V	0.803	1.00
414_T	418_A	0.799	1.00
265_G	268_A	0.799	1.00
179_T	182_F	0.797	1.00
193_I	196_R	0.796	1.00
385_E	389_T	0.793	1.00
112_G	115_I	0.789	1.00
28_P	31_A	0.787	1.00
369_E	372_L	0.786	1.00
219_F	222_E	0.783	1.00
394_N	397_N	0.780	1.00
220_Y	345_I	0.780	1.00
413_V	417_A	0.780	1.00
364_M	367_M	0.778	1.00
235_L	344_F	0.778	1.00
418_A	421_K	0.776	1.00
170_L	173_V	0.773	1.00
402_A	405_E	0.773	1.00
388_R	391_I	0.773	1.00
34_I	38_L	0.773	1.00
231_T	344_F	0.771	1.00
41_K	200_E	0.771	1.00
105_I	114_Q	0.770	1.00
111_I	115_I	0.763	1.00
203_H	206_V	0.762	1.00
416_V	422_M	0.761	1.00
150_V	180_L	0.761	1.00
362_R	365_D	0.760	1.00
404_A	407_L	0.758	1.00
401_T	405_E	0.755	1.00
411_D	414_T	0.755	1.00
166_I	170_L	0.753	1.00
394_N	398_F	0.752	1.00
402_A	406_L	0.749	1.00
409_D	413_V	0.749	1.00
368_K	372_L	0.748	1.00
372_L	377_E	0.745	1.00
252_R	256_E	0.744	1.00
114_Q	118_L	0.743	1.00
38_L	64_K	0.741	1.00
415_V	419_A	0.740	1.00
368_K	371_T	0.735	1.00
390_T	393_E	0.734	1.00
353_L	364_M	0.734	1.00
406_L	412_A	0.733	1.00
83_L	86_Q	0.732	1.00
393_E	396_L	0.731	1.00
228_K	232_L	0.729	1.00
412_A	417_A	0.727	1.00
212_T	216_I	0.727	1.00
179_T	184_A	0.727	1.00
205_K	208_A	0.725	1.00
179_T	185_T	0.725	1.00
374_E	377_E	0.723	1.00
319_P	328_R	0.719	1.00
413_V	416_V	0.717	1.00
390_T	394_N	0.717	1.00
33_T	37_G	0.716	1.00
190_I	196_R	0.713	1.00
356_I	361_K	0.712	1.00
143_L	146_V	0.712	1.00
162_F	169_I	0.711	1.00
115_I	140_T	0.711	1.00
417_A	421_K	0.710	1.00
360_T	367_M	0.710	1.00
411_D	419_A	0.708	1.00
86_Q	306_D	0.708	1.00
384_V	388_R	0.707	1.00
65_I	74_A	0.707	1.00
386_R	390_T	0.707	1.00
116_R	120_K	0.705	1.00
391_I	395_N	0.704	1.00
412_A	419_A	0.701	1.00
348_R	351_S	0.701	1.00
359_T	362_R	0.700	1.00
351_S	355_A	0.699	1.00
377_E	380_Q	0.698	1.00
162_F	167_E	0.697	1.00
270_G	275_L	0.695	1.00
192_R	196_R	0.695	1.00
413_V	418_A	0.694	1.00
202_E	205_K	0.693	1.00
56_A	60_P	0.693	1.00
299_D	324_S	0.692	1.00
95_G	102_V	0.690	1.00
111_I	114_Q	0.685	1.00
90_E	94_I	0.684	1.00
229_F	256_E	0.683	1.00
410_H	416_V	0.682	1.00
395_N	399_Y	0.682	1.00
219_F	367_M	0.680	1.00
299_D	328_R	0.680	1.00
109_Q	114_Q	0.680	1.00
373_D	377_E	0.679	1.00
391_I	394_N	0.678	1.00
155_D	327_H	0.678	1.00
111_I	138_R	0.677	1.00
374_E	378_G	0.677	1.00
216_I	225_E	0.676	1.00
61_L	124_I	0.676	1.00
413_V	419_A	0.675	1.00
170_L	174_P	0.673	1.00
418_A	422_M	0.672	1.00
398_F	408_E	0.672	1.00
353_L	356_I	0.671	1.00
219_F	342_M	0.671	1.00
288_K	308_S	0.671	1.00
230_D	234_R	0.671	1.00
416_V	423_A	0.670	1.00
360_T	364_M	0.667	1.00
414_T	419_A	0.667	1.00
406_L	413_V	0.667	1.00
406_L	411_D	0.666	1.00
225_E	346_T	0.664	1.00
223_V	231_T	0.663	1.00
405_E	408_E	0.663	1.00
409_D	417_A	0.663	1.00
45_G	180_L	0.660	1.00
284_L	287_F	0.660	1.00
401_T	408_E	0.659	1.00
246_V	314_Y	0.656	1.00
395_N	400_M	0.654	1.00
357_E	366_R	0.651	1.00
133_L	165_D	0.649	1.00
357_E	361_K	0.648	1.00
184_A	330_G	0.648	1.00
201_P	206_V	0.648	1.00
44_I	181_L	0.646	1.00
47_A	51_T	0.646	1.00
402_A	412_A	0.645	1.00
320_Q	352_M	0.645	1.00
352_M	357_E	0.644	1.00
311_T	337_K	0.644	1.00
243_L	311_T	0.644	1.00
201_P	205_K	0.640	1.00
407_L	410_H	0.640	1.00
57_F	60_P	0.640	1.00
363_K	367_M	0.639	1.00
245_I	295_L	0.639	1.00
408_E	413_V	0.635	1.00
410_H	414_T	0.633	1.00
243_L	287_F	0.632	1.00
406_L	417_A	0.631	1.00
65_I	123_N	0.630	1.00
148_T	178_Q	0.630	1.00
374_E	381_Q	0.630	1.00
32_Q	35_P	0.628	1.00
169_I	173_V	0.628	1.00
113_R	116_R	0.627	1.00
55_A	94_I	0.626	1.00
371_T	376_L	0.626	1.00
48_Q	208_A	0.625	1.00
404_A	411_D	0.624	1.00
408_E	417_A	0.623	1.00
245_I	310_V	0.623	1.00
379_Q	382_V	0.622	1.00
211_M	214_S	0.621	1.00
402_A	407_L	0.620	1.00
283_A	295_L	0.619	1.00
134_D	138_R	0.618	1.00
57_F	78_A	0.618	1.00
109_Q	113_R	0.618	1.00
400_M	403_A	0.618	1.00
411_D	420_I	0.612	1.00
178_Q	185_T	0.611	1.00
388_R	392_S	0.610	1.00
407_L	413_V	0.609	1.00
220_Y	340_M	0.609	1.00
331_R	334_R	0.608	1.00
310_V	332_T	0.607	1.00
357_E	364_M	0.605	1.00
25_E	31_A	0.605	1.00
249_R	320_Q	0.604	1.00
271_I	300_V	0.604	1.00
114_Q	117_A	0.603	1.00
388_R	393_E	0.603	1.00
385_E	388_R	0.602	1.00
281_M	284_L	0.601	1.00
116_R	119_K	0.599	1.00
95_G	100_A	0.599	1.00
399_Y	406_L	0.597	1.00
322_P	354_R	0.597	1.00
395_N	401_T	0.596	1.00
236_L	294_V	0.592	1.00
176_E	185_T	0.592	1.00
170_L	177_H	0.592	1.00
44_I	194_A	0.592	1.00
391_I	396_L	0.591	1.00
418_A	423_A	0.589	1.00
200_E	204_V	0.588	1.00
115_I	135_H	0.588	1.00
372_L	375_A	0.587	1.00
404_A	409_D	0.587	1.00
217_Q	365_D	0.587	1.00
166_I	169_I	0.587	1.00
249_R	317_D	0.586	1.00
156_E	160_M	0.586	1.00
369_E	376_L	0.586	1.00
228_K	235_L	0.585	1.00
409_D	415_V	0.585	1.00
204_V	208_A	0.584	1.00
164_D	171_S	0.583	1.00
384_V	387_L	0.583	1.00
376_L	380_Q	0.582	1.00
135_H	139_R	0.582	1.00
163_I	170_L	0.581	1.00
308_S	337_K	0.581	1.00
387_L	393_E	0.576	1.00
162_F	165_D	0.575	1.00
220_Y	223_V	0.574	1.00
72_I	125_I	0.573	1.00
121_N	146_V	0.572	1.00
64_K	178_Q	0.569	1.00
410_H	415_V	0.568	1.00
397_N	400_M	0.568	1.00
389_T	392_S	0.567	1.00
408_E	418_A	0.565	1.00
351_S	357_E	0.565	1.00
217_Q	338_T	0.564	1.00
370_P	375_A	0.564	1.00
414_T	422_M	0.564	1.00
58_G	62_V	0.562	1.00
66_N	98_K	0.561	1.00
396_L	403_A	0.560	1.00
77_I	151_M	0.560	1.00
394_N	401_T	0.559	1.00
232_L	257_L	0.559	1.00
259_E	263_L	0.559	1.00
403_A	413_V	0.559	1.00
32_Q	204_V	0.558	1.00
407_L	417_A	0.558	1.00
217_Q	367_M	0.558	1.00
35_P	38_L	0.558	1.00
376_L	379_Q	0.557	1.00
236_L	266_Y	0.557	1.00
407_L	414_T	0.557	1.00
376_L	383_T	0.556	1.00
34_I	59_I	0.556	1.00
131_R	134_D	0.556	1.00
373_D	376_L	0.555	1.00
277_Q	281_M	0.555	1.00
356_I	359_T	0.550	1.00
399_Y	404_A	0.550	1.00
390_T	395_N	0.549	1.00
392_S	398_F	0.549	1.00
261_L	294_V	0.549	1.00
189_P	197_F	0.549	1.00
28_P	59_I	0.549	1.00
32_Q	202_E	0.548	1.00
72_I	146_V	0.548	1.00
411_D	416_V	0.547	1.00
408_E	416_V	0.546	1.00
163_I	174_P	0.544	1.00
409_D	416_V	0.544	1.00
412_A	420_I	0.543	1.00
400_M	404_A	0.542	1.00
401_T	411_D	0.540	1.00
353_L	358_Q	0.540	1.00
405_E	423_A	0.539	1.00
389_T	395_N	0.539	1.00
416_V	421_K	0.539	1.00
394_N	399_Y	0.539	1.00
72_I	147_N	0.538	1.00
178_Q	184_A	0.538	1.00
84_A	126_V	0.537	1.00
381_Q	388_R	0.536	1.00
400_M	407_L	0.536	1.00
329_I	343_T	0.533	1.00
224_Q	347_P	0.532	1.00
65_I	73_Q	0.530	1.00
405_E	412_A	0.530	1.00
302_A	324_S	0.530	1.00
392_S	403_A	0.529	0.99
400_M	405_E	0.528	0.99
31_A	35_P	0.527	0.99
33_T	45_G	0.527	0.99
345_I	353_L	0.527	0.99
409_D	414_T	0.527	0.99
417_A	423_A	0.527	0.99
36_L	41_K	0.527	0.99
386_R	389_T	0.526	0.99
189_P	194_A	0.526	0.99
370_P	378_G	0.526	0.99
322_P	359_T	0.526	0.99
363_K	366_R	0.524	0.99
191_K	196_R	0.524	0.99
46_Q	186_M	0.523	0.99
375_A	383_T	0.522	0.99
356_I	363_K	0.522	0.99
212_T	215_N	0.522	0.99
315_N	319_P	0.521	0.99
358_Q	361_K	0.519	0.99
241_P	311_T	0.518	0.99
74_A	124_I	0.517	0.99
409_D	420_I	0.517	0.99
111_I	140_T	0.515	0.99
102_V	126_V	0.515	0.99
290_G	293_E	0.514	0.99
415_V	421_K	0.514	0.99
414_T	420_I	0.514	0.99
413_V	420_I	0.514	0.99
382_V	385_E	0.513	0.99
349_E	352_M	0.512	0.99
113_R	117_A	0.512	0.99
179_T	183_S	0.512	0.99
236_L	261_L	0.511	0.99
222_E	366_R	0.511	0.99
77_I	157_M	0.511	0.99
66_N	73_Q	0.510	0.99
405_E	414_T	0.510	0.99
392_S	402_A	0.509	0.99
391_I	408_E	0.509	0.99
260_A	263_L	0.508	0.99
245_I	313_V	0.507	0.99
377_E	381_Q	0.507	0.99
399_Y	405_E	0.507	0.99
388_R	394_N	0.505	0.99
398_F	402_A	0.503	0.99
399_Y	407_L	0.503	0.99
389_T	393_E	0.501	0.99
407_L	416_V	0.501	0.99
272_H	275_L	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4pxaA	1	0.7611	100	0.29	Contact Map
4nhoA	1	0.749	100	0.295	Contact Map
4c9bA	1	0.7551	100	0.302	Contact Map
4ljyA	1	0.7854	100	0.305	Contact Map
4d25A	1	0.753	100	0.305	Contact Map
2db3A	1	0.751	100	0.308	Contact Map
3eiqA	1	0.7166	100	0.312	Contact Map
1s2mA	1	0.7632	100	0.317	Contact Map
4ct4B	1	0.7591	100	0.321	Contact Map
3fmpB	1	0.413	100	0.322	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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